EuRBPDB

Description

Ensembl ID: ENSG00000008869 (Gene tree)
Gene ID: 54497
Gene Symbol: HEATR5B
Alias: KIAA1414|DKFZp686P15184
Full Name: HEAT repeat containing 5B
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 115,993 bases
Position: chr2:36,968,383-37,084,375
Accession: 29273
RBP type: non-canonical RBP
Summary: (HEAT Repeat Containing 5B) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include binding. An important paralog of this gene is HEATR5A.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000467978	HEATR5B-203	611	-	-	- (aa)	-	-
ENST00000478810	HEATR5B-205	750	-	-	- (aa)	-	-
ENST00000425467	HEATR5B-202	433	-	ENSP00000408222	115 (aa)	-	H7C2X3
ENST00000233099	HEATR5B-201	6905	XM_006712034	ENSP00000233099	2071 (aa)	XP_006712097	Q9P2D3
ENST00000471051	HEATR5B-204	836	-	-	- (aa)	-	-

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000008869	Electrocardiography	1E-9	27659466
ENSG00000008869	Electrocardiography	2E-9	27577874
ENSG00000008869	Electrocardiography	2E-9	27577874

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000008869	rs17020136	2	37020872	?	QRS duration	27659466			EFO_0005054\|EFO_0005055
ENSG00000008869	rs17020136	2	37020872	T	QRS duration	27577874	[NR] millisecond decrease	0.51	EFO_0005055
ENSG00000008869	rs17020136	2	37020872	T	QRS duration	27577874	[0.32-0.64] millisecond decrease	0.48	EFO_0005055
ENSG00000008869	rs17020136	2	37020872	C	QRS duration	30012220	[0.25-0.43] ms increase	0.338887	EFO_0005055
ENSG00000008869	rs17038861	2	37006122	?	White blood cell count	30595370			EFO_0004308
ENSG00000008869	rs13408514	2	36975863	C	Systolic blood pressure	30578418	[0.14-0.28] mmHg decrease	0.2062	EFO_0006335
ENSG00000008869	rs17020136	2	37020872	C	QRS duration	30012220	[0.26-0.53] ms increase	0.392939	EFO_0005055

Protein-Protein Interaction (PPI)

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	30126976.	IPI	Function
GO:0005829	cytosol	-	IEA	Component
GO:0006897	endocytosis	21873635.	IBA	Process
GO:0008104	protein localization	21873635.	IBA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0030139	endocytic vesicle	21873635.	IBA	Component
GO:0042147	retrograde transport, endosome to Golgi	21873635.	IBA	Process