EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000010165 (Gene tree)
Gene ID: 51603
Gene Symbol: EEF1AKNMT
Alias: CGI-01|KIAA0859|DFNB26|METTL13
Full Name: eEF1A lysine and N-terminal methyltransferase
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 32,403 bases
Position: chr1:171,781,621-171,814,023
Accession: 24248
RBP type: canonical RBP
Summary: EEF1AKNMT (EEF1A Lysine And N-Terminal Methyltransferase) is a Protein Coding gene. Diseases associated with EEF1AKNMT include Deafness, Autosomal Recessive 26, Modifier Of and Deafness, Autosomal Recessive 26. An important paralog of this gene is EEF1AKMT4.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000354920	Methyltransf_31	PF13847.6	5.9e-17	1	1
ENSP00000356711	Methyltransf_31	PF13847.6	2.2e-16	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000362019	EEF1AKNMT-202	3022	XM_017001459	ENSP00000355393	613 (aa)	XP_016856948	Q8N6R0
ENST00000478330	EEF1AKNMT-206	580	-	-	- (aa)	-	-
ENST00000367737	EEF1AKNMT-203	2865	-	ENSP00000356711	543 (aa)	-	Q8N6R0
ENST00000485629	EEF1AKNMT-207	759	-	-	- (aa)	-	-
ENST00000476386	EEF1AKNMT-205	283	-	-	- (aa)	-	-
ENST00000466643	EEF1AKNMT-204	841	-	-	- (aa)	-	-
ENST00000361735	EEF1AKNMT-201	3327	XM_017001458	ENSP00000354920	699 (aa)	XP_016856947	Q8N6R0

Gene Model

Click here to download ENSG00000010165's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000010165	Iron	7.7580000E-004	19880490
ENSG00000010165	Hypertension	2.8302867E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000010165	rs34320898	1	171789999	C	Intelligence	29942086	z-score increase	5.949	EFO_0004337

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000010165's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000010165	EEF1AKNMT	100	61.589	ENSAPOG00000019423	mettl13	100	48.942	Acanthochromis_polyacanthus
ENSG00000010165	EEF1AKNMT	100	61.333	ENSACIG00000013889	mettl13	100	49.229	Amphilophus_citrinellus
ENSG00000010165	EEF1AKNMT	99	61.589	ENSAOCG00000002679	mettl13	99	49.438	Amphiprion_ocellaris
ENSG00000010165	EEF1AKNMT	99	61.589	ENSAPEG00000012673	mettl13	99	49.579	Amphiprion_percula
ENSG00000010165	EEF1AKNMT	99	61.333	ENSATEG00000016999	mettl13	99	49.650	Anabas_testudineus
ENSG00000010165	EEF1AKNMT	100	66.613	ENSAPLG00000004413	EEF1AKNMT	99	65.571	Anas_platyrhynchos
ENSG00000010165	EEF1AKNMT	100	67.176	ENSACAG00000012638	EEF1AKNMT	99	64.051	Anolis_carolinensis
ENSG00000010165	EEF1AKNMT	100	98.013	ENSANAG00000022221	EEF1AKNMT	100	96.567	Aotus_nancymaae
ENSG00000010165	EEF1AKNMT	97	61.333	ENSACLG00000013194	mettl13	100	50.140	Astatotilapia_calliptera
ENSG00000010165	EEF1AKNMT	99	62.667	ENSAMXG00000012760	mettl13	99	51.763	Astyanax_mexicanus
ENSG00000010165	EEF1AKNMT	100	96.026	ENSBTAG00000017721	EEF1AKNMT	100	92.857	Bos_taurus
ENSG00000010165	EEF1AKNMT	97	40.260	WBGene00015282	C01B10.8	98	33.573	Caenorhabditis_elegans
ENSG00000010165	EEF1AKNMT	100	96.689	ENSCJAG00000009633	EEF1AKNMT	96	95.136	Callithrix_jacchus
ENSG00000010165	EEF1AKNMT	87	92.951	ENSCAFG00000014885	-	100	92.951	Canis_familiaris
ENSG00000010165	EEF1AKNMT	100	95.364	ENSCAFG00000029162	-	100	93.571	Canis_familiaris
ENSG00000010165	EEF1AKNMT	100	95.364	ENSCAFG00020021213	EEF1AKNMT	100	93.714	Canis_lupus_dingo
ENSG00000010165	EEF1AKNMT	100	96.026	ENSCHIG00000021452	EEF1AKNMT	100	92.857	Capra_hircus
ENSG00000010165	EEF1AKNMT	100	92.715	ENSTSYG00000012467	EEF1AKNMT	100	92.143	Carlito_syrichta
ENSG00000010165	EEF1AKNMT	91	94.059	ENSCAPG00000017409	EEF1AKNMT	94	84.769	Cavia_aperea
ENSG00000010165	EEF1AKNMT	100	94.702	ENSCPOG00000004377	EEF1AKNMT	100	92.286	Cavia_porcellus
ENSG00000010165	EEF1AKNMT	100	98.013	ENSCCAG00000022211	EEF1AKNMT	100	96.567	Cebus_capucinus
ENSG00000010165	EEF1AKNMT	100	99.338	ENSCATG00000021485	EEF1AKNMT	100	98.283	Cercocebus_atys
ENSG00000010165	EEF1AKNMT	100	95.364	ENSCLAG00000014345	EEF1AKNMT	100	92.704	Chinchilla_lanigera
ENSG00000010165	EEF1AKNMT	100	99.338	ENSCSAG00000011646	EEF1AKNMT	100	98.283	Chlorocebus_sabaeus
ENSG00000010165	EEF1AKNMT	100	94.040	ENSCHOG00000004871	EEF1AKNMT	100	93.143	Choloepus_hoffmanni
ENSG00000010165	EEF1AKNMT	84	72.427	ENSCPBG00000017017	EEF1AKNMT	89	72.948	Chrysemys_picta_bellii
ENSG00000010165	EEF1AKNMT	91	54.248	ENSCING00000024131	-	93	43.741	Ciona_intestinalis
ENSG00000010165	EEF1AKNMT	91	52.980	ENSCSAVG00000002978	-	98	47.107	Ciona_savignyi
ENSG00000010165	EEF1AKNMT	100	99.338	ENSCANG00000001873	EEF1AKNMT	100	97.997	Colobus_angolensis_palliatus
ENSG00000010165	EEF1AKNMT	100	92.715	ENSCGRG00001014417	Mettl13	100	91.000	Cricetulus_griseus_chok1gshd
ENSG00000010165	EEF1AKNMT	100	92.715	ENSCGRG00000009062	Mettl13	100	91.000	Cricetulus_griseus_crigri
ENSG00000010165	EEF1AKNMT	99	62.252	ENSCSEG00000004233	mettl13	99	50.424	Cynoglossus_semilaevis
ENSG00000010165	EEF1AKNMT	80	60.265	ENSCVAG00000003860	mettl13	96	46.921	Cyprinodon_variegatus
ENSG00000010165	EEF1AKNMT	100	66.667	ENSDARG00000010905	mettl13	99	57.190	Danio_rerio
ENSG00000010165	EEF1AKNMT	99	89.333	ENSDORG00000011976	Mettl13	99	85.735	Dipodomys_ordii
ENSG00000010165	EEF1AKNMT	97	56.579	FBgn0032873	CG2614	96	42.775	Drosophila_melanogaster
ENSG00000010165	EEF1AKNMT	100	93.377	ENSETEG00000015471	-	100	89.429	Echinops_telfairi
ENSG00000010165	EEF1AKNMT	71	91.406	ENSETEG00000003655	-	68	89.202	Echinops_telfairi
ENSG00000010165	EEF1AKNMT	86	43.056	ENSEBUG00000011508	mettl13	87	38.710	Eptatretus_burgeri
ENSG00000010165	EEF1AKNMT	100	96.689	ENSEASG00005018330	EEF1AKNMT	100	94.286	Equus_asinus_asinus
ENSG00000010165	EEF1AKNMT	98	96.689	ENSECAG00000018565	EEF1AKNMT	97	94.178	Equus_caballus
ENSG00000010165	EEF1AKNMT	100	76.873	ENSEEUG00000000985	EEF1AKNMT	100	77.350	Erinaceus_europaeus
ENSG00000010165	EEF1AKNMT	96	63.333	ENSELUG00000000238	mettl13	96	51.744	Esox_lucius
ENSG00000010165	EEF1AKNMT	100	96.689	ENSFCAG00000025669	EEF1AKNMT	100	94.000	Felis_catus
ENSG00000010165	EEF1AKNMT	94	69.102	ENSFALG00000007811	EEF1AKNMT	90	69.102	Ficedula_albicollis
ENSG00000010165	EEF1AKNMT	100	92.053	ENSFDAG00000017108	EEF1AKNMT	100	91.857	Fukomys_damarensis
ENSG00000010165	EEF1AKNMT	96	60.265	ENSFHEG00000000968	mettl13	96	46.852	Fundulus_heteroclitus
ENSG00000010165	EEF1AKNMT	91	60.667	ENSGMOG00000012344	mettl13	93	51.054	Gadus_morhua
ENSG00000010165	EEF1AKNMT	100	67.430	ENSGALG00000003206	EEF1AKNMT	100	65.714	Gallus_gallus
ENSG00000010165	EEF1AKNMT	95	60.959	ENSGAFG00000006873	mettl13	84	61.842	Gambusia_affinis
ENSG00000010165	EEF1AKNMT	99	58.940	ENSGACG00000014705	mettl13	99	49.298	Gasterosteus_aculeatus
ENSG00000010165	EEF1AKNMT	100	72.801	ENSGAGG00000018083	EEF1AKNMT	100	73.228	Gopherus_agassizii
ENSG00000010165	EEF1AKNMT	87	99.506	ENSGGOG00000004671	-	98	99.344	Gorilla_gorilla
ENSG00000010165	EEF1AKNMT	100	99.674	ENSGGOG00000027207	-	100	99.571	Gorilla_gorilla
ENSG00000010165	EEF1AKNMT	97	61.333	ENSHBUG00000017712	mettl13	97	50.727	Haplochromis_burtoni
ENSG00000010165	EEF1AKNMT	100	92.053	ENSHGLG00000011737	METTL13	100	91.857	Heterocephalus_glaber_female
ENSG00000010165	EEF1AKNMT	100	92.053	ENSHGLG00100001495	METTL13	100	91.857	Heterocephalus_glaber_male
ENSG00000010165	EEF1AKNMT	100	58.667	ENSHCOG00000017290	mettl13	100	48.506	Hippocampus_comes
ENSG00000010165	EEF1AKNMT	99	63.333	ENSIPUG00000012806	mettl13	99	52.260	Ictalurus_punctatus
ENSG00000010165	EEF1AKNMT	100	95.364	ENSSTOG00000003852	EEF1AKNMT	100	93.286	Ictidomys_tridecemlineatus
ENSG00000010165	EEF1AKNMT	100	92.020	ENSJJAG00000020197	Mettl13	100	91.714	Jaculus_jaculus
ENSG00000010165	EEF1AKNMT	96	61.333	ENSKMAG00000003207	mettl13	96	51.391	Kryptolebias_marmoratus
ENSG00000010165	EEF1AKNMT	99	58.000	ENSLBEG00000008944	mettl13	99	48.315	Labrus_bergylta
ENSG00000010165	EEF1AKNMT	99	73.510	ENSLACG00000011875	EEF1AKNMT	99	65.951	Latimeria_chalumnae
ENSG00000010165	EEF1AKNMT	65	53.680	ENSLOCG00000010429	mettl13	94	55.991	Lepisosteus_oculatus
ENSG00000010165	EEF1AKNMT	100	93.377	ENSLAFG00000008601	EEF1AKNMT	100	91.571	Loxodonta_africana
ENSG00000010165	EEF1AKNMT	100	99.338	ENSMFAG00000045158	EEF1AKNMT	100	98.283	Macaca_fascicularis
ENSG00000010165	EEF1AKNMT	100	99.338	ENSMMUG00000007266	EEF1AKNMT	100	97.997	Macaca_mulatta
ENSG00000010165	EEF1AKNMT	100	99.338	ENSMNEG00000035859	EEF1AKNMT	100	98.283	Macaca_nemestrina
ENSG00000010165	EEF1AKNMT	100	99.338	ENSMLEG00000029475	EEF1AKNMT	100	98.426	Mandrillus_leucophaeus
ENSG00000010165	EEF1AKNMT	91	61.333	ENSMAMG00000016683	mettl13	92	51.891	Mastacembelus_armatus
ENSG00000010165	EEF1AKNMT	97	61.333	ENSMZEG00005019629	mettl13	100	50.140	Maylandia_zebra
ENSG00000010165	EEF1AKNMT	100	68.515	ENSMGAG00000004201	EEF1AKNMT	100	68.429	Meleagris_gallopavo
ENSG00000010165	EEF1AKNMT	100	94.040	ENSMAUG00000021447	Mettl13	100	91.286	Mesocricetus_auratus
ENSG00000010165	EEF1AKNMT	100	97.351	ENSMICG00000037588	EEF1AKNMT	100	94.714	Microcebus_murinus
ENSG00000010165	EEF1AKNMT	100	92.715	ENSMOCG00000011261	Mettl13	100	91.000	Microtus_ochrogaster
ENSG00000010165	EEF1AKNMT	100	61.333	ENSMMOG00000003239	mettl13	100	48.596	Mola_mola
ENSG00000010165	EEF1AKNMT	100	89.404	ENSMODG00000003886	EEF1AKNMT	100	84.692	Monodelphis_domestica
ENSG00000010165	EEF1AKNMT	96	62.252	ENSMALG00000007161	mettl13	97	50.798	Monopterus_albus
ENSG00000010165	EEF1AKNMT	100	90.728	MGP_CAROLIEiJ_G0014771	Mettl13	100	90.143	Mus_caroli
ENSG00000010165	EEF1AKNMT	100	90.728	ENSMUSG00000026694	Mettl13	100	89.857	Mus_musculus
ENSG00000010165	EEF1AKNMT	100	92.053	MGP_PahariEiJ_G0028008	Mettl13	100	90.714	Mus_pahari
ENSG00000010165	EEF1AKNMT	100	90.728	MGP_SPRETEiJ_G0015578	Mettl13	100	89.714	Mus_spretus
ENSG00000010165	EEF1AKNMT	100	92.020	ENSMPUG00000015625	EEF1AKNMT	98	92.154	Mustela_putorius_furo
ENSG00000010165	EEF1AKNMT	100	96.689	ENSMLUG00000012259	EEF1AKNMT	100	93.429	Myotis_lucifugus
ENSG00000010165	EEF1AKNMT	100	93.377	ENSNGAG00000017426	Mettl13	100	92.143	Nannospalax_galili
ENSG00000010165	EEF1AKNMT	100	60.667	ENSNBRG00000023713	mettl13	100	49.719	Neolamprologus_brichardi
ENSG00000010165	EEF1AKNMT	100	99.338	ENSNLEG00000015209	EEF1AKNMT	100	98.283	Nomascus_leucogenys
ENSG00000010165	EEF1AKNMT	100	92.053	ENSODEG00000013057	EEF1AKNMT	100	91.559	Octodon_degus
ENSG00000010165	EEF1AKNMT	97	61.333	ENSONIG00000002768	mettl13	100	49.860	Oreochromis_niloticus
ENSG00000010165	EEF1AKNMT	90	84.158	ENSOANG00000000905	EEF1AKNMT	100	73.394	Ornithorhynchus_anatinus
ENSG00000010165	EEF1AKNMT	100	97.351	ENSOCUG00000008257	EEF1AKNMT	100	94.429	Oryctolagus_cuniculus
ENSG00000010165	EEF1AKNMT	91	59.740	ENSORLG00000022310	mettl13	93	51.372	Oryzias_latipes
ENSG00000010165	EEF1AKNMT	91	59.740	ENSORLG00020008764	mettl13	93	51.220	Oryzias_latipes_hni
ENSG00000010165	EEF1AKNMT	91	59.740	ENSORLG00015004926	mettl13	93	51.524	Oryzias_latipes_hsok
ENSG00000010165	EEF1AKNMT	91	60.667	ENSOMEG00000023355	mettl13	77	51.067	Oryzias_melastigma
ENSG00000010165	EEF1AKNMT	100	97.351	ENSOGAG00000011755	EEF1AKNMT	100	93.714	Otolemur_garnettii
ENSG00000010165	EEF1AKNMT	100	96.026	ENSOARG00000013736	EEF1AKNMT	100	92.857	Ovis_aries
ENSG00000010165	EEF1AKNMT	100	99.674	ENSPPAG00000039457	EEF1AKNMT	100	99.571	Pan_paniscus
ENSG00000010165	EEF1AKNMT	100	96.689	ENSPPRG00000006545	EEF1AKNMT	100	94.143	Panthera_pardus
ENSG00000010165	EEF1AKNMT	100	99.837	ENSPTRG00000001682	EEF1AKNMT	100	99.714	Pan_troglodytes
ENSG00000010165	EEF1AKNMT	100	98.675	ENSPANG00000013789	EEF1AKNMT	100	98.426	Papio_anubis
ENSG00000010165	EEF1AKNMT	85	62.000	ENSPKIG00000009076	mettl13	92	52.782	Paramormyrops_kingsleyae
ENSG00000010165	EEF1AKNMT	57	69.577	ENSPSIG00000007651	EEF1AKNMT	88	71.875	Pelodiscus_sinensis
ENSG00000010165	EEF1AKNMT	99	60.265	ENSPMGG00000013233	mettl13	99	49.575	Periophthalmus_magnuspinnatus
ENSG00000010165	EEF1AKNMT	100	94.040	ENSPEMG00000019591	Mettl13	100	91.155	Peromyscus_maniculatus_bairdii
ENSG00000010165	EEF1AKNMT	100	89.404	ENSPCIG00000029847	EEF1AKNMT	87	84.286	Phascolarctos_cinereus
ENSG00000010165	EEF1AKNMT	96	61.589	ENSPFOG00000014838	mettl13	96	50.512	Poecilia_formosa
ENSG00000010165	EEF1AKNMT	91	61.589	ENSPLAG00000014327	mettl13	93	51.372	Poecilia_latipinna
ENSG00000010165	EEF1AKNMT	96	61.589	ENSPMEG00000002612	mettl13	96	50.512	Poecilia_mexicana
ENSG00000010165	EEF1AKNMT	91	60.265	ENSPREG00000000863	mettl13	93	50.915	Poecilia_reticulata
ENSG00000010165	EEF1AKNMT	100	99.338	ENSPPYG00000000509	EEF1AKNMT	100	98.999	Pongo_abelii
ENSG00000010165	EEF1AKNMT	94	96.026	ENSPCAG00000005276	EEF1AKNMT	100	90.827	Procavia_capensis
ENSG00000010165	EEF1AKNMT	100	96.689	ENSPCOG00000016474	EEF1AKNMT	100	94.714	Propithecus_coquereli
ENSG00000010165	EEF1AKNMT	100	61.333	ENSPNYG00000008414	mettl13	100	50.000	Pundamilia_nyererei
ENSG00000010165	EEF1AKNMT	100	64.667	ENSPNAG00000007903	mettl13	100	51.899	Pygocentrus_nattereri
ENSG00000010165	EEF1AKNMT	100	98.675	ENSRROG00000038013	EEF1AKNMT	100	98.140	Rhinopithecus_roxellana
ENSG00000010165	EEF1AKNMT	100	97.351	ENSSBOG00000028175	EEF1AKNMT	100	96.280	Saimiri_boliviensis_boliviensis
ENSG00000010165	EEF1AKNMT	100	87.417	ENSSHAG00000017290	EEF1AKNMT	100	83.143	Sarcophilus_harrisii
ENSG00000010165	EEF1AKNMT	94	62.667	ENSSFOG00015002093	mettl13	100	52.833	Scleropages_formosus
ENSG00000010165	EEF1AKNMT	97	60.000	ENSSMAG00000017192	mettl13	97	51.799	Scophthalmus_maximus
ENSG00000010165	EEF1AKNMT	91	62.000	ENSSDUG00000016028	mettl13	92	53.881	Seriola_dumerili
ENSG00000010165	EEF1AKNMT	91	62.000	ENSSLDG00000018397	mettl13	95	60.819	Seriola_lalandi_dorsalis
ENSG00000010165	EEF1AKNMT	91	61.589	ENSSPAG00000014359	mettl13	93	52.496	Stegastes_partitus
ENSG00000010165	EEF1AKNMT	100	96.689	ENSSSCG00000015483	EEF1AKNMT	100	96.711	Sus_scrofa
ENSG00000010165	EEF1AKNMT	100	67.763	ENSTGUG00000017274	EEF1AKNMT	100	66.904	Taeniopygia_guttata
ENSG00000010165	EEF1AKNMT	99	62.000	ENSTRUG00000016505	mettl13	100	48.873	Takifugu_rubripes
ENSG00000010165	EEF1AKNMT	94	61.333	ENSTNIG00000002653	mettl13	96	50.808	Tetraodon_nigroviridis
ENSG00000010165	EEF1AKNMT	100	94.702	ENSTTRG00000005192	EEF1AKNMT	100	88.429	Tursiops_truncatus
ENSG00000010165	EEF1AKNMT	100	95.364	ENSUAMG00000002862	EEF1AKNMT	100	92.561	Ursus_americanus
ENSG00000010165	EEF1AKNMT	100	95.364	ENSUMAG00000017931	EEF1AKNMT	100	94.714	Ursus_maritimus
ENSG00000010165	EEF1AKNMT	100	93.648	ENSVVUG00000014638	EEF1AKNMT	100	93.429	Vulpes_vulpes
ENSG00000010165	EEF1AKNMT	100	66.000	ENSXETG00000010438	eef1aknmt	100	60.801	Xenopus_tropicalis
ENSG00000010165	EEF1AKNMT	95	61.589	ENSXCOG00000008785	mettl13	95	50.815	Xiphophorus_couchianus
ENSG00000010165	EEF1AKNMT	95	61.589	ENSXMAG00000011288	mettl13	95	50.815	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	21516116.25416956.29408807.	IPI	Function
GO:0008168	methyltransferase activity	-	IEA	Function
GO:0032259	methylation	-	IEA	Process