EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000013523 (Gene tree)
Gene ID: 23357
Gene Symbol: ANGEL1
Alias: Ccr4e|KIAA0759
Full Name: angel homolog 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 42,296 bases
Position: chr14:76,786,178-76,828,473
Accession: 19961
RBP type: canonical RBP
Summary: (Angel Homolog 1) is a Protein Coding gene. An important paralog of this gene is ANGEL2.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000251089	Exo_endo_phos	PF03372.23	3.7e-45	1	1
ENSP00000451534	Exo_endo_phos	PF03372.23	2e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000557179	ANGEL1-205	1427	-	ENSP00000451534	235 (aa)	-	G3V414
ENST00000556298	ANGEL1-204	727	-	ENSP00000451568	129 (aa)	-	G3V437
ENST00000557497	ANGEL1-206	577	-	ENSP00000498076	131 (aa)	-	-
ENST00000554941	ANGEL1-202	694	-	-	- (aa)	-	-
ENST00000251089	ANGEL1-201	5176	XM_017021115	ENSP00000251089	670 (aa)	XP_016876604	Q9UNK9
ENST00000555079	ANGEL1-203	553	-	ENSP00000452287	67 (aa)	-	G3V5C4

Gene Model

Click here to download ENSG00000013523's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000013523	Fibrinogen	6.22803643169883E-5	17903294
ENSG00000013523	Fibrinogen	1.73907581706195E-5	17903294

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000013523	rs7152947	14	76825750	A	Venlafaxine response in generalised anxiety disorder (remitters vs non-remitters after 12 weeks)	28437668		5.88	EFO_0006328\|EFO_1001892

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000013523's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000013523	ANGEL1	89	35.577	ENSG00000174606	ANGEL2	100	46.905

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000013523	ANGEL1	89	42.130	ENSAPOG00000010431	angel1	66	46.471	Acanthochromis_polyacanthus
ENSG00000013523	ANGEL1	99	89.836	ENSAMEG00000018359	ANGEL1	100	89.836	Ailuropoda_melanoleuca
ENSG00000013523	ANGEL1	89	41.429	ENSACIG00000008392	angel1	66	47.598	Amphilophus_citrinellus
ENSG00000013523	ANGEL1	89	42.991	ENSAOCG00000003735	angel1	67	45.318	Amphiprion_ocellaris
ENSG00000013523	ANGEL1	88	43.056	ENSATEG00000001862	angel1	63	46.531	Anabas_testudineus
ENSG00000013523	ANGEL1	100	59.701	ENSAPLG00000012908	ANGEL1	99	60.352	Anas_platyrhynchos
ENSG00000013523	ANGEL1	99	58.971	ENSACAG00000017113	ANGEL1	99	58.971	Anolis_carolinensis
ENSG00000013523	ANGEL1	100	93.284	ENSANAG00000023393	ANGEL1	100	93.731	Aotus_nancymaae
ENSG00000013523	ANGEL1	89	45.498	ENSACLG00000024873	angel1	73	47.421	Astatotilapia_calliptera
ENSG00000013523	ANGEL1	97	41.772	ENSAMXG00000030578	angel1	58	49.244	Astyanax_mexicanus
ENSG00000013523	ANGEL1	100	89.866	ENSBTAG00000019454	ANGEL1	100	89.866	Bos_taurus
ENSG00000013523	ANGEL1	100	95.522	ENSCJAG00000020726	ANGEL1	100	94.179	Callithrix_jacchus
ENSG00000013523	ANGEL1	100	91.045	ENSCAFG00000017147	ANGEL1	97	92.604	Canis_familiaris
ENSG00000013523	ANGEL1	100	92.687	ENSCAFG00020001638	ANGEL1	100	92.687	Canis_lupus_dingo
ENSG00000013523	ANGEL1	100	92.090	ENSCHIG00000016482	ANGEL1	100	92.090	Capra_hircus
ENSG00000013523	ANGEL1	100	88.507	ENSTSYG00000011919	ANGEL1	100	88.507	Carlito_syrichta
ENSG00000013523	ANGEL1	90	70.755	ENSCAPG00000017618	ANGEL1	92	78.125	Cavia_aperea
ENSG00000013523	ANGEL1	100	89.552	ENSCPOG00000011475	ANGEL1	100	89.552	Cavia_porcellus
ENSG00000013523	ANGEL1	100	95.522	ENSCCAG00000035390	ANGEL1	100	95.075	Cebus_capucinus
ENSG00000013523	ANGEL1	100	96.269	ENSCATG00000041296	ANGEL1	100	96.269	Cercocebus_atys
ENSG00000013523	ANGEL1	100	89.552	ENSCLAG00000012161	ANGEL1	100	89.552	Chinchilla_lanigera
ENSG00000013523	ANGEL1	100	95.522	ENSCSAG00000011939	ANGEL1	95	96.148	Chlorocebus_sabaeus
ENSG00000013523	ANGEL1	100	86.567	ENSCHOG00000006847	ANGEL1	100	93.157	Choloepus_hoffmanni
ENSG00000013523	ANGEL1	99	61.821	ENSCPBG00000026277	ANGEL1	93	61.821	Chrysemys_picta_bellii
ENSG00000013523	ANGEL1	100	96.418	ENSCANG00000042848	ANGEL1	100	96.418	Colobus_angolensis_palliatus
ENSG00000013523	ANGEL1	100	90.896	ENSCGRG00001002965	Angel1	100	90.896	Cricetulus_griseus_chok1gshd
ENSG00000013523	ANGEL1	99	89.593	ENSCGRG00000005245	Angel1	99	89.593	Cricetulus_griseus_crigri
ENSG00000013523	ANGEL1	62	48.700	ENSCSEG00000000707	angel1	60	48.700	Cynoglossus_semilaevis
ENSG00000013523	ANGEL1	88	44.712	ENSCVAG00000022214	angel1	67	49.533	Cyprinodon_variegatus
ENSG00000013523	ANGEL1	99	39.143	ENSDARG00000077567	angel1	99	39.286	Danio_rerio
ENSG00000013523	ANGEL1	100	90.597	ENSDNOG00000008557	ANGEL1	100	90.597	Dasypus_novemcinctus
ENSG00000013523	ANGEL1	100	89.552	ENSDORG00000007719	Angel1	100	88.823	Dipodomys_ordii
ENSG00000013523	ANGEL1	90	63.981	ENSETEG00000015911	ANGEL1	80	71.136	Echinops_telfairi
ENSG00000013523	ANGEL1	65	46.021	ENSEBUG00000015994	angel1	76	44.637	Eptatretus_burgeri
ENSG00000013523	ANGEL1	100	91.642	ENSEASG00005020021	ANGEL1	100	91.642	Equus_asinus_asinus
ENSG00000013523	ANGEL1	100	92.537	ENSECAG00000023551	ANGEL1	100	91.186	Equus_caballus
ENSG00000013523	ANGEL1	97	39.496	ENSELUG00000006883	angel1	65	48.276	Esox_lucius
ENSG00000013523	ANGEL1	100	91.493	ENSFCAG00000011721	ANGEL1	100	91.493	Felis_catus
ENSG00000013523	ANGEL1	100	58.209	ENSFALG00000006446	ANGEL1	96	63.636	Ficedula_albicollis
ENSG00000013523	ANGEL1	97	88.563	ENSFDAG00000002450	ANGEL1	99	88.563	Fukomys_damarensis
ENSG00000013523	ANGEL1	95	40.870	ENSFHEG00000017936	angel1	62	47.732	Fundulus_heteroclitus
ENSG00000013523	ANGEL1	95	40.851	ENSGMOG00000015390	angel1	100	47.771	Gadus_morhua
ENSG00000013523	ANGEL1	99	61.347	ENSGALG00000010372	ANGEL1	98	61.347	Gallus_gallus
ENSG00000013523	ANGEL1	88	44.286	ENSGAFG00000017078	angel1	67	47.390	Gambusia_affinis
ENSG00000013523	ANGEL1	89	38.028	ENSGACG00000007487	angel1	99	46.495	Gasterosteus_aculeatus
ENSG00000013523	ANGEL1	89	69.524	ENSGAGG00000020478	ANGEL1	91	61.086	Gopherus_agassizii
ENSG00000013523	ANGEL1	100	98.507	ENSGGOG00000017040	ANGEL1	100	96.856	Gorilla_gorilla
ENSG00000013523	ANGEL1	89	44.811	ENSHBUG00000018316	angel1	64	47.129	Haplochromis_burtoni
ENSG00000013523	ANGEL1	100	88.209	ENSHGLG00000019080	ANGEL1	100	88.209	Heterocephalus_glaber_female
ENSG00000013523	ANGEL1	100	88.060	ENSHGLG00100002743	ANGEL1	100	88.060	Heterocephalus_glaber_male
ENSG00000013523	ANGEL1	89	43.836	ENSHCOG00000015296	angel1	77	43.594	Hippocampus_comes
ENSG00000013523	ANGEL1	97	41.453	ENSIPUG00000008142	angel1	59	48.052	Ictalurus_punctatus
ENSG00000013523	ANGEL1	100	92.537	ENSSTOG00000011127	ANGEL1	100	92.747	Ictidomys_tridecemlineatus
ENSG00000013523	ANGEL1	100	88.507	ENSJJAG00000024403	Angel1	100	88.507	Jaculus_jaculus
ENSG00000013523	ANGEL1	89	43.779	ENSKMAG00000002129	angel1	67	47.461	Kryptolebias_marmoratus
ENSG00000013523	ANGEL1	89	42.593	ENSLBEG00000000168	angel1	61	46.653	Labrus_bergylta
ENSG00000013523	ANGEL1	91	53.738	ENSLACG00000014598	ANGEL1	100	54.941	Latimeria_chalumnae
ENSG00000013523	ANGEL1	92	50.000	ENSLOCG00000010649	angel1	99	53.119	Lepisosteus_oculatus
ENSG00000013523	ANGEL1	100	89.851	ENSLAFG00000012241	ANGEL1	100	89.851	Loxodonta_africana
ENSG00000013523	ANGEL1	100	96.269	ENSMFAG00000045195	ANGEL1	100	96.269	Macaca_fascicularis
ENSG00000013523	ANGEL1	100	95.821	ENSMMUG00000018551	ANGEL1	100	95.821	Macaca_mulatta
ENSG00000013523	ANGEL1	100	96.119	ENSMNEG00000032987	ANGEL1	100	96.119	Macaca_nemestrina
ENSG00000013523	ANGEL1	100	96.269	ENSMLEG00000036323	ANGEL1	100	96.269	Mandrillus_leucophaeus
ENSG00000013523	ANGEL1	98	40.928	ENSMAMG00000006257	angel1	73	46.586	Mastacembelus_armatus
ENSG00000013523	ANGEL1	89	45.498	ENSMZEG00005008711	angel1	64	47.421	Maylandia_zebra
ENSG00000013523	ANGEL1	99	59.853	ENSMGAG00000012816	ANGEL1	99	59.853	Meleagris_gallopavo
ENSG00000013523	ANGEL1	100	91.194	ENSMAUG00000015525	Angel1	100	91.194	Mesocricetus_auratus
ENSG00000013523	ANGEL1	100	94.030	ENSMICG00000003631	ANGEL1	100	92.996	Microcebus_murinus
ENSG00000013523	ANGEL1	100	90.299	ENSMOCG00000022911	Angel1	100	90.299	Microtus_ochrogaster
ENSG00000013523	ANGEL1	100	73.485	ENSMODG00000005548	ANGEL1	94	80.936	Monodelphis_domestica
ENSG00000013523	ANGEL1	89	43.458	ENSMALG00000015492	angel1	68	48.203	Monopterus_albus
ENSG00000013523	ANGEL1	100	90.746	MGP_CAROLIEiJ_G0017978	Angel1	100	90.746	Mus_caroli
ENSG00000013523	ANGEL1	100	90.597	ENSMUSG00000021257	Angel1	100	90.597	Mus_musculus
ENSG00000013523	ANGEL1	100	90.448	MGP_PahariEiJ_G0029737	Angel1	100	90.448	Mus_pahari
ENSG00000013523	ANGEL1	100	90.746	MGP_SPRETEiJ_G0018824	Angel1	100	90.746	Mus_spretus
ENSG00000013523	ANGEL1	100	89.313	ENSMPUG00000009009	ANGEL1	95	91.371	Mustela_putorius_furo
ENSG00000013523	ANGEL1	100	90.356	ENSMLUG00000008935	ANGEL1	100	90.356	Myotis_lucifugus
ENSG00000013523	ANGEL1	100	89.552	ENSNGAG00000017628	Angel1	100	89.552	Nannospalax_galili
ENSG00000013523	ANGEL1	61	46.635	ENSNBRG00000003668	angel1	60	46.635	Neolamprologus_brichardi
ENSG00000013523	ANGEL1	100	97.015	ENSNLEG00000016631	ANGEL1	100	97.015	Nomascus_leucogenys
ENSG00000013523	ANGEL1	97	80.586	ENSMEUG00000015224	ANGEL1	100	80.586	Notamacropus_eugenii
ENSG00000013523	ANGEL1	100	82.609	ENSOPRG00000013802	ANGEL1	89	92.527	Ochotona_princeps
ENSG00000013523	ANGEL1	100	89.552	ENSODEG00000012416	ANGEL1	100	88.955	Octodon_degus
ENSG00000013523	ANGEL1	89	45.327	ENSONIG00000012018	angel1	97	49.676	Oreochromis_niloticus
ENSG00000013523	ANGEL1	97	68.702	ENSOANG00000010589	ANGEL1	97	68.702	Ornithorhynchus_anatinus
ENSG00000013523	ANGEL1	100	89.552	ENSOCUG00000009531	ANGEL1	100	89.104	Oryctolagus_cuniculus
ENSG00000013523	ANGEL1	89	44.976	ENSORLG00000016639	angel1	69	47.399	Oryzias_latipes
ENSG00000013523	ANGEL1	89	44.976	ENSORLG00020005780	angel1	71	47.249	Oryzias_latipes_hni
ENSG00000013523	ANGEL1	89	44.762	ENSORLG00015005540	angel1	71	46.768	Oryzias_latipes_hsok
ENSG00000013523	ANGEL1	89	45.755	ENSOMEG00000020430	angel1	68	49.378	Oryzias_melastigma
ENSG00000013523	ANGEL1	100	92.697	ENSOGAG00000000180	ANGEL1	100	92.697	Otolemur_garnettii
ENSG00000013523	ANGEL1	100	88.060	ENSOARG00000002192	ANGEL1	95	87.827	Ovis_aries
ENSG00000013523	ANGEL1	100	100.000	ENSPPAG00000029410	ANGEL1	100	97.305	Pan_paniscus
ENSG00000013523	ANGEL1	100	91.493	ENSPPRG00000005702	ANGEL1	100	91.493	Panthera_pardus
ENSG00000013523	ANGEL1	100	88.060	ENSPTIG00000014991	ANGEL1	99	89.426	Panthera_tigris_altaica
ENSG00000013523	ANGEL1	100	100.000	ENSPTRG00000006569	ANGEL1	100	99.403	Pan_troglodytes
ENSG00000013523	ANGEL1	100	95.522	ENSPANG00000023844	ANGEL1	100	92.985	Papio_anubis
ENSG00000013523	ANGEL1	99	41.079	ENSPKIG00000003362	angel1	99	41.079	Paramormyrops_kingsleyae
ENSG00000013523	ANGEL1	89	66.190	ENSPSIG00000018028	ANGEL1	99	62.478	Pelodiscus_sinensis
ENSG00000013523	ANGEL1	89	34.272	ENSPMGG00000019074	angel1	83	44.598	Periophthalmus_magnuspinnatus
ENSG00000013523	ANGEL1	100	90.746	ENSPEMG00000021771	Angel1	100	90.746	Peromyscus_maniculatus_bairdii
ENSG00000013523	ANGEL1	100	80.775	ENSPCIG00000026915	ANGEL1	100	80.775	Phascolarctos_cinereus
ENSG00000013523	ANGEL1	88	46.190	ENSPFOG00000014241	angel1	71	47.708	Poecilia_formosa
ENSG00000013523	ANGEL1	88	45.714	ENSPLAG00000013616	angel1	67	47.500	Poecilia_latipinna
ENSG00000013523	ANGEL1	88	46.190	ENSPMEG00000011478	angel1	65	47.500	Poecilia_mexicana
ENSG00000013523	ANGEL1	88	45.238	ENSPREG00000019202	angel1	65	47.379	Poecilia_reticulata
ENSG00000013523	ANGEL1	100	98.507	ENSPPYG00000006014	ANGEL1	100	97.612	Pongo_abelii
ENSG00000013523	ANGEL1	100	83.582	ENSPCAG00000005781	ANGEL1	68	92.053	Procavia_capensis
ENSG00000013523	ANGEL1	100	92.537	ENSPCOG00000016541	ANGEL1	99	92.687	Propithecus_coquereli
ENSG00000013523	ANGEL1	100	88.060	ENSPVAG00000011762	ANGEL1	100	91.135	Pteropus_vampyrus
ENSG00000013523	ANGEL1	89	45.283	ENSPNYG00000021751	angel1	64	47.327	Pundamilia_nyererei
ENSG00000013523	ANGEL1	97	43.668	ENSPNAG00000010007	angel1	61	50.766	Pygocentrus_nattereri
ENSG00000013523	ANGEL1	100	90.448	ENSRNOG00000010567	Angel1	100	90.448	Rattus_norvegicus
ENSG00000013523	ANGEL1	100	96.418	ENSRBIG00000027844	ANGEL1	100	96.418	Rhinopithecus_bieti
ENSG00000013523	ANGEL1	100	96.418	ENSRROG00000037388	ANGEL1	100	96.474	Rhinopithecus_roxellana
ENSG00000013523	ANGEL1	100	95.522	ENSSBOG00000007093	ANGEL1	100	95.192	Saimiri_boliviensis_boliviensis
ENSG00000013523	ANGEL1	99	80.030	ENSSHAG00000012214	ANGEL1	99	80.030	Sarcophilus_harrisii
ENSG00000013523	ANGEL1	89	42.991	ENSSMAG00000005086	angel1	63	45.726	Scophthalmus_maximus
ENSG00000013523	ANGEL1	89	42.523	ENSSLDG00000021499	angel1	60	47.000	Seriola_lalandi_dorsalis
ENSG00000013523	ANGEL1	100	78.295	ENSSARG00000014273	ANGEL1	100	86.555	Sorex_araneus
ENSG00000013523	ANGEL1	99	58.850	ENSSPUG00000014165	ANGEL1	99	58.850	Sphenodon_punctatus
ENSG00000013523	ANGEL1	87	42.384	ENSSPAG00000009116	angel1	76	42.384	Stegastes_partitus
ENSG00000013523	ANGEL1	100	91.940	ENSSSCG00000002390	ANGEL1	100	91.940	Sus_scrofa
ENSG00000013523	ANGEL1	99	60.534	ENSTGUG00000012264	ANGEL1	99	60.534	Taeniopygia_guttata
ENSG00000013523	ANGEL1	90	46.364	ENSTRUG00000015473	angel1	64	48.602	Takifugu_rubripes
ENSG00000013523	ANGEL1	89	36.058	ENSTNIG00000017422	angel1	99	44.495	Tetraodon_nigroviridis
ENSG00000013523	ANGEL1	100	88.060	ENSTBEG00000011007	ANGEL1	100	84.568	Tupaia_belangeri
ENSG00000013523	ANGEL1	99	91.330	ENSTTRG00000013227	ANGEL1	99	91.330	Tursiops_truncatus
ENSG00000013523	ANGEL1	100	92.537	ENSUAMG00000011796	ANGEL1	100	92.537	Ursus_americanus
ENSG00000013523	ANGEL1	100	88.060	ENSUMAG00000007496	ANGEL1	100	92.949	Ursus_maritimus
ENSG00000013523	ANGEL1	100	88.060	ENSVPAG00000009546	ANGEL1	100	84.989	Vicugna_pacos
ENSG00000013523	ANGEL1	100	90.840	ENSVVUG00000003153	ANGEL1	95	92.296	Vulpes_vulpes
ENSG00000013523	ANGEL1	88	44.286	ENSXMAG00000014605	angel1	65	47.799	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005634	nucleus	23814182.	IDA	Component
GO:0005783	endoplasmic reticulum	23814182.	IDA	Component
GO:0005801	cis-Golgi network	23814182.	IDA	Component
GO:0005829	cytosol	23814182.	IDA	Component
GO:0008190	eukaryotic initiation factor 4E binding	23814182.	IDA	Function
GO:0019904	protein domain specific binding	23814182.	IDA	Function
GO:0048471	perinuclear region of cytoplasm	23814182.	IDA	Component