EuRBPDB

Description

Ensembl ID: ENSG00000014123 (Gene tree)
Gene ID: 23376
Gene Symbol: UFL1
Alias: NLBP|Maxer|RCAD|KIAA0776
Full Name: UFM1 specific ligase 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 33,682 bases
Position: chr6:96,521,595-96,555,276
Accession: 23039
RBP type: non-canonical RBP
Summary: (UFM1 Specific Ligase 1) is a Protein Coding gene. Diseases associated with UFL1 include Renal Cysts And Diabetes Syndrome. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. Gene Ontology (GO) annotations related to this gene include ligase activity and UFM1 transferase activity.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000461673	UFL1-202	458	-	-	- (aa)	-	-
ENST00000369278	UFL1-201	4224	-	ENSP00000358283	794 (aa)	-	O94874

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000014123	UFL1	100	90.554	ENSMUSG00000040359	Ufl1	100	90.554	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001649	osteoblast differentiation	16210410.	HDA	Process
GO:0005515	protein binding	20018847.20164180.20228063.25219498.	IPI	Function
GO:0005737	cytoplasm	20164180.	IDA	Component
GO:0005783	endoplasmic reticulum	20018847.20531390.	IDA	Component
GO:0005789	endoplasmic reticulum membrane	20531390.	IDA	Component
GO:0005829	cytosol	-	IEA	Component
GO:0008284	positive regulation of cell proliferation	20531390.	IMP	Process
GO:0016020	membrane	16210410.	HDA	Component
GO:0031397	negative regulation of protein ubiquitination	20164180.	IDA	Process
GO:0032088	negative regulation of NF-kappaB transcription factor activity	20164180.20228063.	IMP	Process
GO:0032434	regulation of proteasomal ubiquitin-dependent protein catabolic process	20228063.	IMP	Process
GO:0032880	regulation of protein localization	20531390.	IMP	Process
GO:0032991	protein-containing complex	20531390.	IDA	Component
GO:0033146	regulation of intracellular estrogen receptor signaling pathway	25219498.	IDA	Process
GO:0034976	response to endoplasmic reticulum stress	23152784.	IDA	Process
GO:0043005	neuron projection	-	IEA	Component
GO:0043066	negative regulation of apoptotic process	-	IEA	Process
GO:0060252	positive regulation of glial cell proliferation	-	IEA	Process
GO:0071568	UFM1 transferase activity	20018847.	IDA	Function
GO:0071569	protein ufmylation	20018847.	IDA	Process
GO:0071569	protein ufmylation	23152784.	IMP	Process
GO:1902065	response to L-glutamate	-	IEA	Process
GO:1990592	protein K69-linked ufmylation	25219498.	IDA	Process