EuRBPDB

Description

Ensembl ID: ENSG00000030066 (Gene tree)
Gene ID: 23279
Gene Symbol: NUP160
Alias: KIAA0197|FLJ22583
Full Name: nucleoporin 160
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 70,469 bases
Position: chr11:47,778,087-47,848,555
Accession: 18017
RBP type: non-canonical RBP
Summary: NUP160 is 1 of up to 60 proteins that make up the 120-MD nuclear pore complex, which mediates nucleoplasmic transport.[supplied by OMIM, Apr 2004]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000531016	NUP160-210	634	-	-	- (aa)	-	-
ENST00000526870	NUP160-203	1537	-	ENSP00000431495	224 (aa)	-	Q12769
ENST00000378460	NUP160-201	5376	-	ENSP00000367721	1436 (aa)	-	Q12769
ENST00000532773	NUP160-211	593	-	-	- (aa)	-	-
ENST00000528071	NUP160-206	4138	-	ENSP00000432367	1123 (aa)	-	E9PR16
ENST00000527750	NUP160-205	353	-	-	- (aa)	-	-
ENST00000527126	NUP160-204	527	-	-	- (aa)	-	-
ENST00000530326	NUP160-209	4811	-	ENSP00000433590	1314 (aa)	-	G3V198
ENST00000528501	NUP160-207	1961	-	ENSP00000433964	102 (aa)	-	E9PSI3
ENST00000526569	NUP160-202	533	-	-	- (aa)	-	-
ENST00000529863	NUP160-208	348	-	-	- (aa)	-	-

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000030066	Body Mass Index	8.939e-005	19060910

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000030066	rs11039409	11	47814169	A	Experiencing mood swings	29500382	z score decrease	5.55	EFO_0008475
ENSG00000030066	rs34563280	11	47789945	C	Plateletcrit	27863252	[0.019-0.034] unit increase	0.02640469	EFO_0007985
ENSG00000030066	rs11039409	11	47814169		Depressed affect	29942085	[0.011-0.021] unit increase	0.01574	EFO_0003761\|EFO_0004247
ENSG00000030066	rs3816605	11	47835701	T	Body mass index	30108127	[NR] unit increase	0.02	EFO_0004340
ENSG00000030066	rs7131262	11	47814750	A	Neuroticism	29942085	z score increase	6.063	EFO_0007660
ENSG00000030066	rs548825905	11	47800679	?	Heel bone mineral density	30048462	[0.067-0.119] unit decrease	0.0927925	EFO_0009270
ENSG00000030066	rs79145982	11	47839194	T	Pulse pressure	30578418	[0.16-0.3] mmHg decrease	0.2319	EFO_0005763
ENSG00000030066	rs2290850	11	47786222	C	Neuroticism	30643256	[0.0078-0.0142] unit decrease	0.011033266	EFO_0007660
ENSG00000030066	rs2290850	11	47786222	C	Depressive symptoms	30643256	[0.0049-0.0089] unit decrease	0.006892594	EFO_0007006
ENSG00000030066	rs2290850	11	47786222	C	Life satisfaction	30643256	[0.0062-0.0117] unit decrease	0.008952587	EFO_0007869
ENSG00000030066	rs2290850	11	47786222	C	Positive affect	30643256	[0.0059-0.0108] unit decrease	0.008333924	EFO_0007869

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000030066	NUP160	99	92.204	ENSMUSG00000051329	Nup160	100	92.725	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000776	kinetochore	15146057.	IDA	Component
GO:0005515	protein binding	15146057.25416956.	IPI	Function
GO:0005635	nuclear envelope	-	TAS	Component
GO:0005643	nuclear pore	21873635.	IBA	Component
GO:0005643	nuclear pore	11564755.11684705.17098863.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006110	regulation of glycolytic process	-	TAS	Process
GO:0006406	mRNA export from nucleus	11684705.	IDA	Process
GO:0006406	mRNA export from nucleus	-	TAS	Process
GO:0006409	tRNA export from nucleus	-	TAS	Process
GO:0016032	viral process	-	TAS	Process
GO:0016925	protein sumoylation	-	TAS	Process
GO:0017056	structural constituent of nuclear pore	21873635.	IBA	Function
GO:0017056	structural constituent of nuclear pore	11684705.	IDA	Function
GO:0019083	viral transcription	-	TAS	Process
GO:0031080	nuclear pore outer ring	17360435.	IDA	Component
GO:0031080	nuclear pore outer ring	15146057.17363900.	NAS	Component
GO:0043657	host cell	-	IEA	Component
GO:0060964	regulation of gene silencing by miRNA	-	TAS	Process
GO:0072006	nephron development	30179222.	IMP	Process
GO:0075733	intracellular transport of virus	-	TAS	Process
GO:1900034	regulation of cellular response to heat	-	TAS	Process