EuRBPDB

Description

Ensembl ID: ENSG00000033050 (Gene tree)
Gene ID: 10061
Gene Symbol: ABCF2
Alias: EST133090|ABC28|M-ABC1|HUSSY-18
Full Name: ATP binding cassette subfamily F member 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 19,545 bases
Position: chr7:151,207,830-151,227,374
Accession: 71
RBP type: non-canonical RBP
Summary: This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. ATP-binding cassette proteins transport various molecules across extra- and intracellular membranes. Alterations in this gene may be involved in cancer progression. Related pseudogenes have been identified on chromosomes 3 and 7. [provided by RefSeq, Mar 2019]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000473874	ABCF2-204	648	-	-	- (aa)	-	-
ENST00000468073	ABCF2-203	1031	-	ENSP00000419720	287 (aa)	-	C9JZV3
ENST00000287844	ABCF2-201	3546	XM_017011639	ENSP00000287844	623 (aa)	XP_016867128	Q9UG63
ENST00000477252	ABCF2-205	249	-	-	- (aa)	-	-
ENST00000441774	ABCF2-202	941	-	ENSP00000395785	240 (aa)	-	C9JHK9

Gene Model

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000033050	rs7812088	7	151222743	A	Bone mineral density	22504420	[NR] unit increase	0.05	EFO_0003923
ENSG00000033050	rs1122979	7	151217985	G	IgG glycosylation	23382691	[0.22-0.41] unit increase	0.3134	EFO_0005193
ENSG00000033050	rs1122979	7	151217985	G	IgG glycosylation	23382691	[0.2-0.39] unit increase	0.2982	EFO_0005193
ENSG00000033050	rs1122979	7	151217985	G	IgG glycosylation	23382691	[0.21-0.4] unit increase	0.3046	EFO_0005193
ENSG00000033050	rs1122979	7	151217985	G	IgG glycosylation	23382691	[0.2-0.39] unit increase	0.2945	EFO_0005193
ENSG00000033050	rs1122979	7	151217985	G	IgG glycosylation	23382691	[0.12-0.32] unit decrease	0.2213	EFO_0005193

Protein-Protein Interaction (PPI)

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000033050	ABCF2	97	69.917	FBgn0030672	CG9281	98	69.884	Drosophila_melanogaster
ENSG00000033050	ABCF2	100	98.248	ENSMUSG00000028953	Abcf2	100	98.248	Mus_musculus
ENSG00000033050	ABCF2	92	51.979	YER036C		95	51.979	Saccharomyces_cerevisiae

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005215	transporter activity	9878413.	TAS	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005740	mitochondrial envelope	9878413.	TAS	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0016887	ATPase activity	-	IEA	Function