EuRBPDB

Description

Ensembl ID: ENSG00000033178 (Gene tree)
Gene ID: 55236
Gene Symbol: UBA6
Alias: FLJ10808|UBE1L2
Full Name: ubiquitin like modifier activating enzyme 6
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 88,528 bases
Position: chr4:67,612,652-67,701,179
Accession: 25581
RBP type: non-canonical RBP
Summary: Modification of proteins with ubiquitin (UBB; MIM 191339) or ubiquitin-like proteins controls many signaling networks and requires a ubiquitin-activating enzyme (E1), a ubiquitin conjugating enzyme (E2), and a ubiquitin protein ligase (E3). UBE1L2 is an E1 enzyme that initiates the activation and conjugation of ubiquitin-like proteins (Jin et al., 2007 [PubMed 17597759]).[supplied by OMIM, Mar 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000514261	UBA6-206	623	-	ENSP00000425091	88 (aa)	-	H0Y9U5
ENST00000506571	UBA6-205	385	-	-	- (aa)	-	-
ENST00000322244	UBA6-201	9564	XM_017008359	ENSP00000313454	1052 (aa)	XP_016863848	A0AVT1
ENST00000429659	UBA6-203	2387	-	-	- (aa)	-	-
ENST00000420827	UBA6-202	1664	-	ENSP00000399234	389 (aa)	-	A0AVT1
ENST00000505673	UBA6-204	812	-	ENSP00000421984	271 (aa)	-	H0Y8S8

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa04120	Ubiquitin mediated proteolysis	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000033178	Blood Pressure	1.2010000E-005	-
ENSG00000033178	Forced Expiratory Volume	7.8380000E-006	-

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0004839	ubiquitin activating enzyme activity	21873635.	IBA	Function
GO:0005515	protein binding	17889673.25416956.25422469.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006511	ubiquitin-dependent protein catabolic process	21873635.	IBA	Process
GO:0006511	ubiquitin-dependent protein catabolic process	17889673.	IMP	Process
GO:0007612	learning	-	IEA	Process
GO:0007626	locomotory behavior	-	IEA	Process
GO:0016567	protein ubiquitination	-	IEA	Process
GO:0016567	protein ubiquitination	17889673.	IMP	Process
GO:0016567	protein ubiquitination	-	TAS	Process
GO:0019780	FAT10 activating enzyme activity	17889673.	IMP	Function
GO:0021764	amygdala development	-	IEA	Process
GO:0021766	hippocampus development	-	IEA	Process
GO:0032446	protein modification by small protein conjugation	21873635.	IBA	Process
GO:0060996	dendritic spine development	-	IEA	Process