EuRBPDB

Description

Ensembl ID: ENSG00000046651 (Gene tree)
Gene ID: 8481
Gene Symbol: OFD1
Alias: 71-7A|JBTS10|CXorf5|RP23
Full Name: OFD1 centriole and centriolar satellite protein
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 55,980 bases
Position: chrX:13,715,423-13,771,402
Accession: 2567
RBP type: non-canonical RBP
Summary: This gene is located on the X chromosome and encodes a centrosomal protein. A knockout mouse model has been used to study the effect of mutations in this gene. The mouse gene is also located on the X chromosome, however, unlike the human gene it is not subject to X inactivation. Mutations in this gene are associated with oral-facial-digital syndrome type I and Simpson-Golabi-Behmel syndrome type 2. Many pseudogenes have been identified; a single pseudogene is found on chromosome 5 while as many as fifteen have been found on the Y chromosome. [provided by RefSeq, Aug 2016]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000464463	OFD1-205	812	-	-	- (aa)	-	-
ENST00000466534	OFD1-206	534	-	-	- (aa)	-	-
ENST00000490265	OFD1-209	4259	-	-	- (aa)	-	-
ENST00000380567	OFD1-203	3736	XM_011545594	ENSP00000369941	872 (aa)	XP_011543896	A6NF31
ENST00000474705	OFD1-207	496	-	-	- (aa)	-	-
ENST00000380550	OFD1-202	3296	-	ENSP00000369923	972 (aa)	-	O75665
ENST00000485052	OFD1-208	685	-	-	- (aa)	-	-
ENST00000398395	OFD1-204	3307	-	ENSP00000381432	338 (aa)	-	A0A0A0MS89
ENST00000340096	OFD1-201	3611	XM_005274606	ENSP00000344314	1012 (aa)	XP_005274663	O75665

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000086	G2/M transition of mitotic cell cycle	-	TAS	Process
GO:0000278	mitotic cell cycle	-	ISS	Process
GO:0005515	protein binding	17761535.19800048.20835237.21988832.23789104.24089205.24997988.26496610.26638075.	IPI	Function
GO:0005634	nucleus	-	IEA	Component
GO:0005813	centrosome	21399614.	IDA	Component
GO:0005814	centriole	20230748.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005929	cilium	20230748.	IDA	Component
GO:0007099	centriole replication	-	ISS	Process
GO:0010389	regulation of G2/M transition of mitotic cell cycle	-	TAS	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0034451	centriolar satellite	-	ISS	Component
GO:0036064	ciliary basal body	20230748.	IDA	Component
GO:0042802	identical protein binding	17761535.	IPI	Function
GO:0043014	alpha-tubulin binding	-	ISS	Function
GO:0043015	gamma-tubulin binding	-	ISS	Function
GO:0060271	cilium assembly	-	ISS	Process
GO:0060287	epithelial cilium movement involved in determination of left/right asymmetry	-	ISS	Process
GO:0090307	mitotic spindle assembly	-	ISS	Process
GO:0097711	ciliary basal body-plasma membrane docking	-	TAS	Process