EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000047188 (Gene tree)
Gene ID: 64848
Gene Symbol: YTHDC2
Alias: FLJ2194|FLJ10053|DKFZp564A186
Full Name: YTH domain containing 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 81,605 bases
Position: chr5:113,513,683-113,595,287
Accession: 24721
RBP type: canonical RBP
Summary: This gene encodes a member of the DEAH (Asp-Glu-Ala-His) subfamily of proteins, part of the DEAD (Asp-Glu-Ala-Asp) box family of RNA helicases. The encoded protein binds to N6-methyladenosine, a common modified RNA nucleotide that is enriched in the stop codons and 3' UTRs of eukaryotic messenger RNAs. Binding of proteins to this modified nucleotide may regulate mRNA translation and stability. This gene may be associated with susceptibility to pancreatic cancer in human patients, and knockdown of this gene resulted in reduced proliferation in a human liver cancer cell line. [provided by RefSeq, Sep 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000423101	R3H	PF01424.22	1.2e-10	1	1
ENSP00000161863	R3H	PF01424.22	3e-10	1	1
ENSP00000422916	R3H	PF01424.22	4.9e-10	1	1
ENSP00000423101	DEAD	PF00270.29	1.3e-09	1	1
ENSP00000161863	DEAD	PF00270.29	4.6e-09	1	1
ENSP00000161863	YTH	PF04146.15	2e-41	1	1
ENSP00000161863	HA2	PF04408.23	2.4e-18	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
29970596	The m6A reader protein YTHDC2 interacts with the small ribosomal subunit and the 5'-3' exoribonuclease XRN1.	RNA	2018 Oct	Kretschmer J	doi: 10.1261/rna.064238.117

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000161863	YTHDC2-201	6316	XM_011543581	ENSP00000161863	1430 (aa)	XP_011541883	Q9H6S0
ENST00000512600	YTHDC2-205	6708	-	-	- (aa)	-	-
ENST00000506333	YTHDC2-203	784	-	-	- (aa)	-	-
ENST00000503857	YTHDC2-202	2138	-	ENSP00000426644	98 (aa)	-	D6RF50
ENST00000507567	YTHDC2-204	693	-	-	- (aa)	-	-
ENST00000514720	YTHDC2-206	536	-	ENSP00000422916	137 (aa)	-	D6R9T8
ENST00000515883	YTHDC2-207	2629	-	ENSP00000423101	739 (aa)	-	D6RA70

Gene Model

Click here to download ENSG00000047188's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000047188	Body Weights and Measures	4.18538902584586E-5	17903300
ENSG00000047188	Body Weights and Measures	4.38873780244098E-5	17903300
ENSG00000047188	Body Weights and Measures	7.37042521352649E-5	17903300
ENSG00000047188	Body Weights and Measures	6.92057409599212E-5	17903300
ENSG00000047188	Triglycerides	8.45932720099363E-5	17903299
ENSG00000047188	Body Height	6.8990000E-005	-
ENSG00000047188	Body Height	7.2200000E-005	-
ENSG00000047188	Body Height	7.4960000E-005	-
ENSG00000047188	Body Height	8.7310000E-005	-
ENSG00000047188	Lipoprotein(a)	8.9560000E-005	-
ENSG00000047188	Erythrocyte Indices	1.3110000E-005	-
ENSG00000047188	Erythrocyte Count	2.0630000E-006	-
ENSG00000047188	Platelet Function Tests	9.6900000E-006	-
ENSG00000047188	Platelet Function Tests	3.0200000E-006	-
ENSG00000047188	Platelet Function Tests	2.2702400E-005	-
ENSG00000047188	Platelet Function Tests	2.0620800E-005	-
ENSG00000047188	Platelet Function Tests	2.6103000E-005	-
ENSG00000047188	Platelet Function Tests	4.2897000E-005	-
ENSG00000047188	Language Tests	2.3133000E-005	-
ENSG00000047188	Language Tests	3.8634000E-005	-
ENSG00000047188	Erythrocyte Indices	4.4560000E-005	-
ENSG00000047188	Arterial Pressure	2.8110000E-006	-
ENSG00000047188	Arterial Pressure	5.8670000E-006	-
ENSG00000047188	Death, Sudden, Cardiac	4E-8	21658281
ENSG00000047188	Anemia, Sickle Cell	8E-6	21326311
ENSG00000047188	Fetal Hemoglobin	8E-6	21326311
ENSG00000047188	Sleep	7E-6	27126917
ENSG00000047188	Alzheimer Disease	9E-7	26830138
ENSG00000047188	Age of Onset	9E-7	26830138

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000047188	rs10077431	5	113591989	A	Type 2 diabetes	30054458	[0.031-0.066] unit decrease	0.0487	EFO_0001360
ENSG00000047188	rs56206672	5	113584063	?	Waist-hip ratio	30595370			EFO_0004343

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000047188's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000047188	YTHDC2	53	49.231	ENSG00000163214	DHX57	71	50.769
ENSG00000047188	YTHDC2	53	44.138	ENSG00000132153	DHX30	64	42.105
ENSG00000047188	YTHDC2	55	46.930	ENSG00000067248	DHX29	53	49.282
ENSG00000047188	YTHDC2	56	33.667	ENSG00000067596	DHX8	56	33.667
ENSG00000047188	YTHDC2	57	43.089	ENSG00000174953	DHX36	98	44.538
ENSG00000047188	YTHDC2	55	48.529	ENSG00000135829	DHX9	60	48.529

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000047188	YTHDC2	71	63.039	ENSAPOG00000013442	YTHDC2	96	62.795	Acanthochromis_polyacanthus
ENSG00000047188	YTHDC2	99	100.000	ENSAMEG00000006598	YTHDC2	99	96.552	Ailuropoda_melanoleuca
ENSG00000047188	YTHDC2	97	64.388	ENSACIG00000012809	YTHDC2	99	63.075	Amphilophus_citrinellus
ENSG00000047188	YTHDC2	89	67.098	ENSAOCG00000018480	YTHDC2	98	73.684	Amphiprion_ocellaris
ENSG00000047188	YTHDC2	95	67.037	ENSAPEG00000014873	YTHDC2	96	73.684	Amphiprion_percula
ENSG00000047188	YTHDC2	97	64.034	ENSATEG00000010847	YTHDC2	98	63.506	Anabas_testudineus
ENSG00000047188	YTHDC2	99	93.382	ENSACAG00000007754	YTHDC2	100	89.236	Anolis_carolinensis
ENSG00000047188	YTHDC2	99	100.000	ENSANAG00000022177	YTHDC2	99	95.512	Aotus_nancymaae
ENSG00000047188	YTHDC2	97	64.286	ENSACLG00000019069	YTHDC2	94	72.932	Astatotilapia_calliptera
ENSG00000047188	YTHDC2	98	74.000	ENSAMXG00000008735	YTHDC2	98	73.786	Astyanax_mexicanus
ENSG00000047188	YTHDC2	99	100.000	ENSBTAG00000014099	YTHDC2	100	96.928	Bos_taurus
ENSG00000047188	YTHDC2	100	95.594	ENSCJAG00000016598	YTHDC2	100	95.594	Callithrix_jacchus
ENSG00000047188	YTHDC2	99	100.000	ENSCAFG00000000224	YTHDC2	99	98.096	Canis_familiaris
ENSG00000047188	YTHDC2	99	100.000	ENSCAFG00020003668	YTHDC2	100	96.364	Canis_lupus_dingo
ENSG00000047188	YTHDC2	99	100.000	ENSCHIG00000026651	YTHDC2	100	96.783	Capra_hircus
ENSG00000047188	YTHDC2	99	100.000	ENSTSYG00000009634	YTHDC2	99	97.254	Carlito_syrichta
ENSG00000047188	YTHDC2	99	70.370	ENSCAPG00000015691	YTHDC2	93	73.459	Cavia_aperea
ENSG00000047188	YTHDC2	99	100.000	ENSCPOG00000000272	YTHDC2	100	96.245	Cavia_porcellus
ENSG00000047188	YTHDC2	100	99.054	ENSCCAG00000037613	YTHDC2	100	98.323	Cebus_capucinus
ENSG00000047188	YTHDC2	100	99.459	ENSCATG00000031670	YTHDC2	100	99.231	Cercocebus_atys
ENSG00000047188	YTHDC2	99	100.000	ENSCLAG00000014076	YTHDC2	100	95.291	Chinchilla_lanigera
ENSG00000047188	YTHDC2	100	99.459	ENSCSAG00000014899	YTHDC2	100	99.161	Chlorocebus_sabaeus
ENSG00000047188	YTHDC2	98	97.015	ENSCHOG00000013323	YTHDC2	91	95.213	Choloepus_hoffmanni
ENSG00000047188	YTHDC2	99	92.647	ENSCPBG00000013876	YTHDC2	100	92.517	Chrysemys_picta_bellii
ENSG00000047188	YTHDC2	99	100.000	ENSCANG00000025759	YTHDC2	100	98.673	Colobus_angolensis_palliatus
ENSG00000047188	YTHDC2	99	99.265	ENSCGRG00001021338	Ythdc2	100	96.930	Cricetulus_griseus_chok1gshd
ENSG00000047188	YTHDC2	100	95.822	ENSCGRG00000010336	Ythdc2	100	95.673	Cricetulus_griseus_crigri
ENSG00000047188	YTHDC2	95	49.858	ENSCSEG00000017911	YTHDC2	97	52.397	Cynoglossus_semilaevis
ENSG00000047188	YTHDC2	97	61.103	ENSCVAG00000021377	YTHDC2	98	60.935	Cyprinodon_variegatus
ENSG00000047188	YTHDC2	97	61.985	ENSDARG00000103525	YTHDC2	98	62.174	Danio_rerio
ENSG00000047188	YTHDC2	99	99.265	ENSDNOG00000012198	YTHDC2	100	94.413	Dasypus_novemcinctus
ENSG00000047188	YTHDC2	99	96.324	ENSDORG00000007057	Ythdc2	96	92.498	Dipodomys_ordii
ENSG00000047188	YTHDC2	75	42.581	FBgn0030833	CG8915	83	34.637	Drosophila_melanogaster
ENSG00000047188	YTHDC2	98	100.000	ENSETEG00000013681	YTHDC2	83	97.297	Echinops_telfairi
ENSG00000047188	YTHDC2	87	55.433	ENSEBUG00000014315	-	86	55.341	Eptatretus_burgeri
ENSG00000047188	YTHDC2	99	100.000	ENSEASG00005015135	YTHDC2	100	97.213	Equus_asinus_asinus
ENSG00000047188	YTHDC2	99	100.000	ENSECAG00000020630	YTHDC2	100	97.213	Equus_caballus
ENSG00000047188	YTHDC2	94	90.698	ENSEEUG00000008580	YTHDC2	86	94.225	Erinaceus_europaeus
ENSG00000047188	YTHDC2	100	76.248	ENSELUG00000015902	YTHDC2	99	73.311	Esox_lucius
ENSG00000047188	YTHDC2	99	100.000	ENSFCAG00000031967	YTHDC2	100	97.133	Felis_catus
ENSG00000047188	YTHDC2	98	82.836	ENSFALG00000000040	-	99	82.590	Ficedula_albicollis
ENSG00000047188	YTHDC2	91	83.257	ENSFALG00000002623	-	99	83.257	Ficedula_albicollis
ENSG00000047188	YTHDC2	99	100.000	ENSFDAG00000008701	YTHDC2	100	95.991	Fukomys_damarensis
ENSG00000047188	YTHDC2	99	60.879	ENSFHEG00000009312	YTHDC2	98	61.621	Fundulus_heteroclitus
ENSG00000047188	YTHDC2	96	81.997	ENSGALG00000000189	YTHDC2	99	81.577	Gallus_gallus
ENSG00000047188	YTHDC2	85	68.354	ENSGAFG00000008158	YTHDC2	92	68.354	Gambusia_affinis
ENSG00000047188	YTHDC2	65	69.014	ENSGACG00000018569	YTHDC2	99	73.951	Gasterosteus_aculeatus
ENSG00000047188	YTHDC2	98	93.284	ENSGAGG00000010063	YTHDC2	100	93.489	Gopherus_agassizii
ENSG00000047188	YTHDC2	100	99.459	ENSGGOG00000014407	YTHDC2	100	99.441	Gorilla_gorilla
ENSG00000047188	YTHDC2	97	62.432	ENSHBUG00000007492	YTHDC2	95	64.167	Haplochromis_burtoni
ENSG00000047188	YTHDC2	99	98.529	ENSHGLG00000019014	YTHDC2	100	95.328	Heterocephalus_glaber_female
ENSG00000047188	YTHDC2	99	98.529	ENSHGLG00100008192	YTHDC2	100	95.328	Heterocephalus_glaber_male
ENSG00000047188	YTHDC2	89	67.857	ENSHCOG00000014281	YTHDC2	94	69.925	Hippocampus_comes
ENSG00000047188	YTHDC2	97	74.965	ENSIPUG00000019561	ythdc2	96	72.948	Ictalurus_punctatus
ENSG00000047188	YTHDC2	100	94.993	ENSSTOG00000013239	YTHDC2	100	94.993	Ictidomys_tridecemlineatus
ENSG00000047188	YTHDC2	99	97.794	ENSJJAG00000017908	Ythdc2	100	92.436	Jaculus_jaculus
ENSG00000047188	YTHDC2	97	63.029	ENSKMAG00000015969	YTHDC2	94	69.925	Kryptolebias_marmoratus
ENSG00000047188	YTHDC2	98	63.585	ENSLBEG00000027926	YTHDC2	98	61.472	Labrus_bergylta
ENSG00000047188	YTHDC2	99	85.915	ENSLACG00000010991	YTHDC2	99	85.774	Latimeria_chalumnae
ENSG00000047188	YTHDC2	99	76.277	ENSLOCG00000009001	YTHDC2	98	77.182	Lepisosteus_oculatus
ENSG00000047188	YTHDC2	99	99.265	ENSLAFG00000003538	YTHDC2	100	97.253	Loxodonta_africana
ENSG00000047188	YTHDC2	100	99.459	ENSMNEG00000040900	YTHDC2	100	99.301	Macaca_nemestrina
ENSG00000047188	YTHDC2	100	99.459	ENSMLEG00000043185	YTHDC2	100	99.301	Mandrillus_leucophaeus
ENSG00000047188	YTHDC2	97	65.100	ENSMAMG00000019193	YTHDC2	98	65.236	Mastacembelus_armatus
ENSG00000047188	YTHDC2	90	72.727	ENSMZEG00005009153	YTHDC2	97	71.223	Maylandia_zebra
ENSG00000047188	YTHDC2	98	70.542	ENSMGAG00000006674	YTHDC2	100	75.329	Meleagris_gallopavo
ENSG00000047188	YTHDC2	99	99.265	ENSMAUG00000016179	Ythdc2	100	96.119	Mesocricetus_auratus
ENSG00000047188	YTHDC2	99	100.000	ENSMICG00000004030	YTHDC2	100	97.356	Microcebus_murinus
ENSG00000047188	YTHDC2	99	98.529	ENSMOCG00000011740	Ythdc2	100	96.725	Microtus_ochrogaster
ENSG00000047188	YTHDC2	99	58.824	ENSMMOG00000011758	YTHDC2	93	63.251	Mola_mola
ENSG00000047188	YTHDC2	99	99.265	ENSMODG00000015671	YTHDC2	100	95.301	Monodelphis_domestica
ENSG00000047188	YTHDC2	96	64.888	ENSMALG00000002782	YTHDC2	93	67.097	Monopterus_albus
ENSG00000047188	YTHDC2	99	99.265	MGP_CAROLIEiJ_G0022248	Ythdc2	100	96.055	Mus_caroli
ENSG00000047188	YTHDC2	99	99.265	ENSMUSG00000034653	Ythdc2	100	96.055	Mus_musculus
ENSG00000047188	YTHDC2	99	99.265	MGP_PahariEiJ_G0018981	Ythdc2	100	95.983	Mus_pahari
ENSG00000047188	YTHDC2	99	99.265	MGP_SPRETEiJ_G0023159	Ythdc2	100	96.255	Mus_spretus
ENSG00000047188	YTHDC2	99	100.000	ENSMPUG00000000755	YTHDC2	99	97.076	Mustela_putorius_furo
ENSG00000047188	YTHDC2	99	99.265	ENSMLUG00000006106	YTHDC2	100	95.073	Myotis_lucifugus
ENSG00000047188	YTHDC2	99	99.265	ENSNGAG00000017798	Ythdc2	100	96.294	Nannospalax_galili
ENSG00000047188	YTHDC2	99	62.466	ENSNBRG00000000762	YTHDC2	95	60.681	Neolamprologus_brichardi
ENSG00000047188	YTHDC2	99	100.000	ENSNLEG00000011648	YTHDC2	100	98.671	Nomascus_leucogenys
ENSG00000047188	YTHDC2	83	95.429	ENSMEUG00000004414	YTHDC2	83	95.429	Notamacropus_eugenii
ENSG00000047188	YTHDC2	87	96.250	ENSOPRG00000000462	YTHDC2	77	100.000	Ochotona_princeps
ENSG00000047188	YTHDC2	99	100.000	ENSODEG00000007804	YTHDC2	100	95.673	Octodon_degus
ENSG00000047188	YTHDC2	97	64.693	ENSONIG00000011601	YTHDC2	99	64.475	Oreochromis_niloticus
ENSG00000047188	YTHDC2	99	68.345	ENSOANG00000011143	-	96	71.429	Ornithorhynchus_anatinus
ENSG00000047188	YTHDC2	98	100.000	ENSOCUG00000012096	YTHDC2	100	97.220	Oryctolagus_cuniculus
ENSG00000047188	YTHDC2	96	51.662	ENSORLG00000019098	YTHDC2	90	73.892	Oryzias_latipes
ENSG00000047188	YTHDC2	97	55.484	ENSORLG00015000390	YTHDC2	83	56.186	Oryzias_latipes_hsok
ENSG00000047188	YTHDC2	97	57.031	ENSOMEG00000014221	YTHDC2	98	57.163	Oryzias_melastigma
ENSG00000047188	YTHDC2	99	100.000	ENSOGAG00000001618	YTHDC2	100	97.423	Otolemur_garnettii
ENSG00000047188	YTHDC2	99	100.000	ENSOARG00000016223	YTHDC2	100	93.759	Ovis_aries
ENSG00000047188	YTHDC2	100	99.650	ENSPPAG00000018854	YTHDC2	100	99.650	Pan_paniscus
ENSG00000047188	YTHDC2	99	100.000	ENSPPRG00000001595	YTHDC2	100	97.133	Panthera_pardus
ENSG00000047188	YTHDC2	98	100.000	ENSPTIG00000021801	YTHDC2	96	97.220	Panthera_tigris_altaica
ENSG00000047188	YTHDC2	100	99.594	ENSPTRG00000017143	YTHDC2	100	99.580	Pan_troglodytes
ENSG00000047188	YTHDC2	100	99.188	ENSPANG00000024470	YTHDC2	99	96.970	Papio_anubis
ENSG00000047188	YTHDC2	97	71.931	ENSPKIG00000016010	YTHDC2	98	72.026	Paramormyrops_kingsleyae
ENSG00000047188	YTHDC2	98	92.537	ENSPSIG00000014798	YTHDC2	100	93.563	Pelodiscus_sinensis
ENSG00000047188	YTHDC2	96	62.098	ENSPMGG00000020677	YTHDC2	97	62.764	Periophthalmus_magnuspinnatus
ENSG00000047188	YTHDC2	99	99.265	ENSPEMG00000018062	Ythdc2	100	96.253	Peromyscus_maniculatus_bairdii
ENSG00000047188	YTHDC2	99	62.509	ENSPMAG00000003218	-	98	62.849	Petromyzon_marinus
ENSG00000047188	YTHDC2	99	98.529	ENSPCIG00000004342	YTHDC2	100	95.455	Phascolarctos_cinereus
ENSG00000047188	YTHDC2	97	63.423	ENSPFOG00000003895	YTHDC2	91	71.429	Poecilia_formosa
ENSG00000047188	YTHDC2	97	62.278	ENSPLAG00000007558	YTHDC2	98	62.464	Poecilia_latipinna
ENSG00000047188	YTHDC2	97	62.912	ENSPMEG00000015205	YTHDC2	99	62.555	Poecilia_mexicana
ENSG00000047188	YTHDC2	97	62.185	ENSPREG00000012096	YTHDC2	95	69.065	Poecilia_reticulata
ENSG00000047188	YTHDC2	100	99.459	ENSPPYG00000015691	YTHDC2	100	98.322	Pongo_abelii
ENSG00000047188	YTHDC2	91	92.529	ENSPCAG00000007733	YTHDC2	90	92.529	Procavia_capensis
ENSG00000047188	YTHDC2	99	99.265	ENSPCOG00000017526	YTHDC2	100	88.555	Propithecus_coquereli
ENSG00000047188	YTHDC2	99	100.000	ENSPVAG00000012364	YTHDC2	93	97.585	Pteropus_vampyrus
ENSG00000047188	YTHDC2	97	64.286	ENSPNYG00000006908	YTHDC2	96	63.100	Pundamilia_nyererei
ENSG00000047188	YTHDC2	98	75.248	ENSPNAG00000010128	YTHDC2	98	75.862	Pygocentrus_nattereri
ENSG00000047188	YTHDC2	99	99.265	ENSRNOG00000039241	Ythdc2	98	93.780	Rattus_norvegicus
ENSG00000047188	YTHDC2	99	100.000	ENSRBIG00000040291	YTHDC2	100	96.047	Rhinopithecus_bieti
ENSG00000047188	YTHDC2	100	99.594	ENSRROG00000039477	YTHDC2	100	99.161	Rhinopithecus_roxellana
ENSG00000047188	YTHDC2	100	99.053	ENSSBOG00000023829	YTHDC2	100	98.531	Saimiri_boliviensis_boliviensis
ENSG00000047188	YTHDC2	99	99.265	ENSSHAG00000003101	YTHDC2	99	96.330	Sarcophilus_harrisii
ENSG00000047188	YTHDC2	98	68.263	ENSSFOG00015003572	ythdc2	98	68.364	Scleropages_formosus
ENSG00000047188	YTHDC2	95	53.638	ENSSMAG00000011225	YTHDC2	97	54.253	Scophthalmus_maximus
ENSG00000047188	YTHDC2	99	66.304	ENSSDUG00000021389	YTHDC2	99	63.802	Seriola_dumerili
ENSG00000047188	YTHDC2	96	67.507	ENSSLDG00000022840	YTHDC2	83	69.323	Seriola_lalandi_dorsalis
ENSG00000047188	YTHDC2	84	98.058	ENSSARG00000000924	YTHDC2	89	96.622	Sorex_araneus
ENSG00000047188	YTHDC2	100	88.934	ENSSPUG00000015912	-	100	88.799	Sphenodon_punctatus
ENSG00000047188	YTHDC2	97	64.378	ENSSPAG00000014889	YTHDC2	98	64.178	Stegastes_partitus
ENSG00000047188	YTHDC2	99	100.000	ENSSSCG00000014211	YTHDC2	100	97.552	Sus_scrofa
ENSG00000047188	YTHDC2	93	81.777	ENSTGUG00000003755	-	100	81.777	Taeniopygia_guttata
ENSG00000047188	YTHDC2	70	80.140	ENSTGUG00000014992	-	97	80.761	Taeniopygia_guttata
ENSG00000047188	YTHDC2	98	57.891	ENSTRUG00000006717	YTHDC2	95	68.182	Takifugu_rubripes
ENSG00000047188	YTHDC2	93	59.023	ENSTNIG00000003707	YTHDC2	99	58.797	Tetraodon_nigroviridis
ENSG00000047188	YTHDC2	85	92.387	ENSTBEG00000006872	YTHDC2	88	92.387	Tupaia_belangeri
ENSG00000047188	YTHDC2	99	95.588	ENSTTRG00000003116	YTHDC2	85	95.270	Tursiops_truncatus
ENSG00000047188	YTHDC2	99	100.000	ENSUAMG00000003688	YTHDC2	99	98.242	Ursus_americanus
ENSG00000047188	YTHDC2	99	100.000	ENSUMAG00000023877	YTHDC2	100	97.384	Ursus_maritimus
ENSG00000047188	YTHDC2	98	87.473	ENSVPAG00000007516	YTHDC2	100	87.133	Vicugna_pacos
ENSG00000047188	YTHDC2	99	100.000	ENSVVUG00000000281	YTHDC2	100	97.492	Vulpes_vulpes
ENSG00000047188	YTHDC2	100	78.666	ENSXETG00000021517	ythdc2	100	77.623	Xenopus_tropicalis
ENSG00000047188	YTHDC2	96	63.099	ENSXCOG00000016406	YTHDC2	96	71.429	Xiphophorus_couchianus
ENSG00000047188	YTHDC2	97	62.295	ENSXMAG00000007618	YTHDC2	98	62.482	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0005515	protein binding	21903422.26742488.29033321.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005783	endoplasmic reticulum	21559518.	IDA	Component
GO:0005783	endoplasmic reticulum	21559518.	IDA	Component
GO:0007286	spermatid development	-	ISS	Process
GO:0008186	RNA-dependent ATPase activity	21559518.	IDA	Function
GO:0034458	3'-5' RNA helicase activity	29033321.	IDA	Function
GO:0034459	ATP-dependent 3'-5' RNA helicase activity	21873635.	IBA	Function
GO:0034612	response to tumor necrosis factor	21559518.	IDA	Process
GO:0035770	ribonucleoprotein granule	-	ISS	Component
GO:0044829	positive regulation by host of viral genome replication	21559518.	IMP	Process
GO:0048599	oocyte development	-	ISS	Process
GO:0051321	meiotic cell cycle	-	IEA	Process
GO:0051729	germline cell cycle switching, mitotic to meiotic cell cycle	-	ISS	Process
GO:0070063	RNA polymerase binding	21559518.	IPI	Function
GO:0070555	response to interleukin-1	21559518.	IDA	Process
GO:1990247	N6-methyladenosine-containing RNA binding	21873635.	IBA	Function
GO:1990247	N6-methyladenosine-containing RNA binding	26318451.28809393.29033321.	IDA	Function