EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000049883 (Gene tree)
Gene ID: 79810
Gene Symbol: PTCD2
Alias: FLJ12598
Full Name: pentatricopeptide repeat domain 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 48,031 bases
Position: chr5:72,320,367-72,368,397
Accession: 25734
RBP type: canonical RBP
Summary: (Pentatricopeptide Repeat Domain 2) is a Protein Coding gene.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000370013	MRP-S27	PF10037.9	6.4e-12	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000308077	PTCD2-201	2195	-	ENSP00000308948	388 (aa)	-	Q8WV60
ENST00000515198	PTCD2-210	881	-	ENSP00000427524	161 (aa)	-	B7Z8R2
ENST00000380639	PTCD2-202	11151	XM_005248601	ENSP00000370013	388 (aa)	XP_005248658	Q8WV60
ENST00000486995	PTCD2-204	2648	-	ENSP00000425606	74 (aa)	-	D6RJH8
ENST00000536805	PTCD2-211	1911	-	ENSP00000444772	216 (aa)	-	Q8WV60
ENST00000510676	PTCD2-208	1001	XM_005248603	ENSP00000426295	203 (aa)	XP_005248660	D6RGK0
ENST00000460837	PTCD2-203	1266	-	-	- (aa)	-	-
ENST00000493283	PTCD2-205	744	-	-	- (aa)	-	-
ENST00000503315	PTCD2-206	1440	-	ENSP00000425773	143 (aa)	-	D6RIZ0
ENST00000511752	PTCD2-209	569	-	ENSP00000429665	93 (aa)	-	E5RHU2
ENST00000503868	PTCD2-207	1653	-	ENSP00000427349	279 (aa)	-	Q8WV60
ENST00000543322	PTCD2-212	2029	XM_017009867	ENSP00000438810	198 (aa)	XP_016865356	F6S289

Gene Model

Click here to download ENSG00000049883's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000049883	rs62364788	5	72361587	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000049883	rs7714219	5	72359028	G	Pulse pressure	27841878	unit decrease	0.164	EFO_0005763

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000049883's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000049883	PTCD2	96	46.133	ENSAPOG00000020682	ptcd2	97	46.133	Acanthochromis_polyacanthus
ENSG00000049883	PTCD2	100	78.818	ENSAMEG00000007194	PTCD2	99	78.182	Ailuropoda_melanoleuca
ENSG00000049883	PTCD2	100	35.749	ENSACIG00000002053	ptcd2	100	40.974	Amphilophus_citrinellus
ENSG00000049883	PTCD2	100	39.901	ENSAOCG00000006616	ptcd2	93	45.753	Amphiprion_ocellaris
ENSG00000049883	PTCD2	100	39.901	ENSAPEG00000022926	ptcd2	93	45.753	Amphiprion_percula
ENSG00000049883	PTCD2	100	54.187	ENSACAG00000009747	PTCD2	97	55.906	Anolis_carolinensis
ENSG00000049883	PTCD2	100	87.113	ENSANAG00000029353	PTCD2	100	87.113	Aotus_nancymaae
ENSG00000049883	PTCD2	98	42.216	ENSACLG00000027742	ptcd2	95	42.216	Astatotilapia_calliptera
ENSG00000049883	PTCD2	94	40.526	ENSAMXG00000029404	ptcd2	88	44.242	Astyanax_mexicanus
ENSG00000049883	PTCD2	100	81.313	ENSBTAG00000014675	PTCD2	100	81.510	Bos_taurus
ENSG00000049883	PTCD2	100	87.629	ENSCJAG00000016364	PTCD2	100	87.629	Callithrix_jacchus
ENSG00000049883	PTCD2	100	79.310	ENSCAFG00000007982	PTCD2	90	76.883	Canis_familiaris
ENSG00000049883	PTCD2	100	79.310	ENSCAFG00020019147	PTCD2	97	78.613	Canis_lupus_dingo
ENSG00000049883	PTCD2	100	82.266	ENSCHIG00000017118	PTCD2	100	82.552	Capra_hircus
ENSG00000049883	PTCD2	100	77.340	ENSCPOG00000040168	PTCD2	100	74.935	Cavia_porcellus
ENSG00000049883	PTCD2	100	87.113	ENSCCAG00000029389	-	100	87.113	Cebus_capucinus
ENSG00000049883	PTCD2	98	86.709	ENSCCAG00000021996	-	98	81.505	Cebus_capucinus
ENSG00000049883	PTCD2	100	91.414	ENSCATG00000019069	PTCD2	100	91.123	Cercocebus_atys
ENSG00000049883	PTCD2	100	76.847	ENSCLAG00000000072	PTCD2	100	74.674	Chinchilla_lanigera
ENSG00000049883	PTCD2	100	92.611	ENSCSAG00000015623	PTCD2	100	91.906	Chlorocebus_sabaeus
ENSG00000049883	PTCD2	68	95.652	ENSCHOG00000010634	PTCD2	100	60.632	Choloepus_hoffmanni
ENSG00000049883	PTCD2	100	54.337	ENSCPBG00000000216	PTCD2	100	54.337	Chrysemys_picta_bellii
ENSG00000049883	PTCD2	100	90.722	ENSCANG00000035636	PTCD2	100	90.722	Colobus_angolensis_palliatus
ENSG00000049883	PTCD2	100	77.340	ENSCGRG00001015289	Ptcd2	84	74.352	Cricetulus_griseus_chok1gshd
ENSG00000049883	PTCD2	100	77.340	ENSCGRG00000006193	Ptcd2	84	74.352	Cricetulus_griseus_crigri
ENSG00000049883	PTCD2	100	41.379	ENSCVAG00000001285	ptcd2	89	45.402	Cyprinodon_variegatus
ENSG00000049883	PTCD2	96	44.118	ENSDARG00000035391	ptcd2	97	44.118	Danio_rerio
ENSG00000049883	PTCD2	100	77.340	ENSDNOG00000008719	PTCD2	100	77.546	Dasypus_novemcinctus
ENSG00000049883	PTCD2	100	79.310	ENSDORG00000004921	Ptcd2	100	78.295	Dipodomys_ordii
ENSG00000049883	PTCD2	99	70.361	ENSETEG00000016542	PTCD2	99	70.361	Echinops_telfairi
ENSG00000049883	PTCD2	100	81.281	ENSEASG00005018038	PTCD2	100	79.634	Equus_asinus_asinus
ENSG00000049883	PTCD2	100	81.773	ENSECAG00000007022	PTCD2	99	79.688	Equus_caballus
ENSG00000049883	PTCD2	99	73.177	ENSEEUG00000014031	PTCD2	99	73.177	Erinaceus_europaeus
ENSG00000049883	PTCD2	100	47.549	ENSELUG00000003584	ptcd2	91	50.997	Esox_lucius
ENSG00000049883	PTCD2	100	82.759	ENSFCAG00000045432	PTCD2	83	73.902	Felis_catus
ENSG00000049883	PTCD2	100	45.813	ENSFALG00000010299	PTCD2	99	51.376	Ficedula_albicollis
ENSG00000049883	PTCD2	100	80.296	ENSFDAG00000018461	PTCD2	100	77.807	Fukomys_damarensis
ENSG00000049883	PTCD2	100	47.783	ENSGMOG00000003637	ptcd2	91	50.997	Gadus_morhua
ENSG00000049883	PTCD2	100	47.783	ENSGALG00000038260	PTCD2	92	51.143	Gallus_gallus
ENSG00000049883	PTCD2	100	57.398	ENSGAGG00000021952	PTCD2	100	57.398	Gopherus_agassizii
ENSG00000049883	PTCD2	100	100.000	ENSGGOG00000010695	PTCD2	100	99.742	Gorilla_gorilla
ENSG00000049883	PTCD2	98	42.480	ENSHBUG00000009191	ptcd2	95	42.480	Haplochromis_burtoni
ENSG00000049883	PTCD2	100	78.325	ENSHGLG00000001234	PTCD2	100	75.718	Heterocephalus_glaber_female
ENSG00000049883	PTCD2	100	78.325	ENSHGLG00100015419	PTCD2	100	75.718	Heterocephalus_glaber_male
ENSG00000049883	PTCD2	97	45.889	ENSHCOG00000001703	ptcd2	95	45.889	Hippocampus_comes
ENSG00000049883	PTCD2	94	39.791	ENSIPUG00000006080	ptcd2	90	44.509	Ictalurus_punctatus
ENSG00000049883	PTCD2	100	83.417	ENSSTOG00000006596	PTCD2	99	80.628	Ictidomys_tridecemlineatus
ENSG00000049883	PTCD2	100	81.773	ENSJJAG00000024388	Ptcd2	100	78.329	Jaculus_jaculus
ENSG00000049883	PTCD2	100	41.379	ENSKMAG00000009329	ptcd2	97	42.246	Kryptolebias_marmoratus
ENSG00000049883	PTCD2	100	43.842	ENSLBEG00000024871	ptcd2	88	45.954	Labrus_bergylta
ENSG00000049883	PTCD2	100	49.020	ENSLOCG00000011122	ptcd2	94	54.670	Lepisosteus_oculatus
ENSG00000049883	PTCD2	95	73.856	ENSLAFG00000004115	PTCD2	100	77.814	Loxodonta_africana
ENSG00000049883	PTCD2	100	91.626	ENSMFAG00000031516	PTCD2	100	90.979	Macaca_fascicularis
ENSG00000049883	PTCD2	100	92.118	ENSMNEG00000007537	PTCD2	100	91.123	Macaca_nemestrina
ENSG00000049883	PTCD2	100	91.414	ENSMLEG00000031093	PTCD2	100	90.979	Mandrillus_leucophaeus
ENSG00000049883	PTCD2	100	42.857	ENSMAMG00000018529	ptcd2	91	47.989	Mastacembelus_armatus
ENSG00000049883	PTCD2	98	42.216	ENSMZEG00005003625	ptcd2	95	42.216	Maylandia_zebra
ENSG00000049883	PTCD2	100	48.276	ENSMGAG00000005033	PTCD2	100	51.724	Meleagris_gallopavo
ENSG00000049883	PTCD2	95	69.935	ENSMAUG00000020253	Ptcd2	100	58.225	Mesocricetus_auratus
ENSG00000049883	PTCD2	100	81.818	ENSMICG00000004535	PTCD2	99	81.137	Microcebus_murinus
ENSG00000049883	PTCD2	100	73.399	ENSMOCG00000019985	Ptcd2	100	73.368	Microtus_ochrogaster
ENSG00000049883	PTCD2	99	57.031	ENSMODG00000001695	PTCD2	100	57.031	Monodelphis_domestica
ENSG00000049883	PTCD2	100	44.828	ENSMALG00000022372	ptcd2	91	49.138	Monopterus_albus
ENSG00000049883	PTCD2	100	75.369	MGP_CAROLIEiJ_G0018829	Ptcd2	100	74.151	Mus_caroli
ENSG00000049883	PTCD2	100	73.399	ENSMUSG00000021650	Ptcd2	100	73.368	Mus_musculus
ENSG00000049883	PTCD2	100	78.325	MGP_PahariEiJ_G0015904	Ptcd2	100	76.240	Mus_pahari
ENSG00000049883	PTCD2	100	74.384	MGP_SPRETEiJ_G0019711	Ptcd2	100	73.890	Mus_spretus
ENSG00000049883	PTCD2	100	80.296	ENSMPUG00000014401	PTCD2	100	79.112	Mustela_putorius_furo
ENSG00000049883	PTCD2	100	77.833	ENSMLUG00000007374	PTCD2	99	78.756	Myotis_lucifugus
ENSG00000049883	PTCD2	100	77.833	ENSNGAG00000005027	Ptcd2	100	74.413	Nannospalax_galili
ENSG00000049883	PTCD2	98	42.480	ENSNBRG00000008174	ptcd2	96	42.480	Neolamprologus_brichardi
ENSG00000049883	PTCD2	99	39.303	ENSNBRG00000000092	-	100	43.030	Neolamprologus_brichardi
ENSG00000049883	PTCD2	100	97.260	ENSNLEG00000004516	PTCD2	100	96.134	Nomascus_leucogenys
ENSG00000049883	PTCD2	99	45.995	ENSMEUG00000014012	-	99	45.995	Notamacropus_eugenii
ENSG00000049883	PTCD2	100	74.384	ENSOPRG00000007290	PTCD2	99	74.160	Ochotona_princeps
ENSG00000049883	PTCD2	100	77.340	ENSODEG00000016417	PTCD2	100	77.023	Octodon_degus
ENSG00000049883	PTCD2	93	44.966	ENSONIG00000011269	ptcd2	91	44.062	Oreochromis_niloticus
ENSG00000049883	PTCD2	100	80.303	ENSOCUG00000007970	PTCD2	100	78.851	Oryctolagus_cuniculus
ENSG00000049883	PTCD2	100	42.365	ENSORLG00000003851	ptcd2	92	45.604	Oryzias_latipes
ENSG00000049883	PTCD2	100	41.379	ENSORLG00020009823	ptcd2	94	45.055	Oryzias_latipes_hni
ENSG00000049883	PTCD2	100	41.872	ENSORLG00015016777	ptcd2	99	46.243	Oryzias_latipes_hsok
ENSG00000049883	PTCD2	100	40.394	ENSOMEG00000012396	ptcd2	87	44.199	Oryzias_melastigma
ENSG00000049883	PTCD2	100	77.778	ENSOGAG00000008390	PTCD2	99	76.486	Otolemur_garnettii
ENSG00000049883	PTCD2	100	81.773	ENSOARG00000005087	PTCD2	99	82.171	Ovis_aries
ENSG00000049883	PTCD2	100	100.000	ENSPPAG00000028480	PTCD2	100	99.485	Pan_paniscus
ENSG00000049883	PTCD2	100	99.227	ENSPTRG00000016968	PTCD2	100	99.227	Pan_troglodytes
ENSG00000049883	PTCD2	100	92.118	ENSPANG00000006611	PTCD2	89	91.884	Papio_anubis
ENSG00000049883	PTCD2	99	44.059	ENSPKIG00000019896	ptcd2	92	47.025	Paramormyrops_kingsleyae
ENSG00000049883	PTCD2	86	56.322	ENSPSIG00000014559	PTCD2	95	61.238	Pelodiscus_sinensis
ENSG00000049883	PTCD2	99	73.506	ENSPEMG00000000884	Ptcd2	100	73.506	Peromyscus_maniculatus_bairdii
ENSG00000049883	PTCD2	99	60.156	ENSPCIG00000029047	PTCD2	100	60.156	Phascolarctos_cinereus
ENSG00000049883	PTCD2	100	39.394	ENSPLAG00000010456	ptcd2	91	44.253	Poecilia_latipinna
ENSG00000049883	PTCD2	100	39.394	ENSPREG00000021797	ptcd2	88	44.253	Poecilia_reticulata
ENSG00000049883	PTCD2	100	93.596	ENSPPYG00000015543	PTCD2	90	92.754	Pongo_abelii
ENSG00000049883	PTCD2	73	81.203	ENSPCAG00000006806	PTCD2	99	67.628	Procavia_capensis
ENSG00000049883	PTCD2	99	76.943	ENSPVAG00000010935	PTCD2	99	76.943	Pteropus_vampyrus
ENSG00000049883	PTCD2	98	42.216	ENSPNYG00000003122	ptcd2	95	42.216	Pundamilia_nyererei
ENSG00000049883	PTCD2	100	43.781	ENSPNAG00000021490	ptcd2	97	47.215	Pygocentrus_nattereri
ENSG00000049883	PTCD2	100	76.847	ENSRNOG00000028403	Ptcd2	100	73.629	Rattus_norvegicus
ENSG00000049883	PTCD2	100	90.640	ENSRBIG00000032929	PTCD2	100	85.052	Rhinopithecus_bieti
ENSG00000049883	PTCD2	100	90.640	ENSRROG00000000080	PTCD2	100	91.123	Rhinopithecus_roxellana
ENSG00000049883	PTCD2	99	85.901	ENSSBOG00000018911	PTCD2	100	85.901	Saimiri_boliviensis_boliviensis
ENSG00000049883	PTCD2	99	59.115	ENSSHAG00000003833	PTCD2	99	59.115	Sarcophilus_harrisii
ENSG00000049883	PTCD2	94	44.211	ENSSFOG00015015415	ptcd2	86	47.147	Scleropages_formosus
ENSG00000049883	PTCD2	100	36.453	ENSSMAG00000010350	ptcd2	90	44.380	Scophthalmus_maximus
ENSG00000049883	PTCD2	100	42.857	ENSSDUG00000008142	ptcd2	90	47.397	Seriola_dumerili
ENSG00000049883	PTCD2	100	43.350	ENSSLDG00000015284	ptcd2	95	47.671	Seriola_lalandi_dorsalis
ENSG00000049883	PTCD2	96	78.065	ENSSARG00000004983	PTCD2	99	70.323	Sorex_araneus
ENSG00000049883	PTCD2	99	51.429	ENSSPUG00000000176	PTCD2	96	51.429	Sphenodon_punctatus
ENSG00000049883	PTCD2	96	44.000	ENSSPAG00000008591	ptcd2	96	44.000	Stegastes_partitus
ENSG00000049883	PTCD2	100	82.828	ENSSSCG00000016975	PTCD2	90	82.338	Sus_scrofa
ENSG00000049883	PTCD2	100	46.798	ENSTGUG00000005705	PTCD2	99	51.304	Taeniopygia_guttata
ENSG00000049883	PTCD2	99	78.497	ENSTBEG00000016559	PTCD2	99	78.497	Tupaia_belangeri
ENSG00000049883	PTCD2	100	81.773	ENSTTRG00000011851	PTCD2	99	82.429	Tursiops_truncatus
ENSG00000049883	PTCD2	100	79.803	ENSUAMG00000007583	PTCD2	90	78.182	Ursus_americanus
ENSG00000049883	PTCD2	100	79.803	ENSUMAG00000007666	PTCD2	100	77.807	Ursus_maritimus
ENSG00000049883	PTCD2	100	81.281	ENSVPAG00000009597	PTCD2	99	81.137	Vicugna_pacos
ENSG00000049883	PTCD2	100	78.818	ENSVVUG00000007299	-	100	77.023	Vulpes_vulpes
ENSG00000049883	PTCD2	100	46.734	ENSXETG00000031652	PTCD2	92	52.707	Xenopus_tropicalis
ENSG00000049883	PTCD2	100	38.889	ENSXMAG00000005940	ptcd2	82	43.966	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001822	kidney development	-	IEA	Process
GO:0001889	liver development	-	IEA	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005739	mitochondrion	18729827.	IDA	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0007005	mitochondrion organization	-	IEA	Process
GO:0048747	muscle fiber development	-	IEA	Process
GO:0050684	regulation of mRNA processing	-	ISS	Process
GO:0055010	ventricular cardiac muscle tissue morphogenesis	-	IEA	Process