Protein ID | Domain | Pfam ID | E-value | Domain number | Total number |
---|---|---|---|---|---|
ENSP00000443149 | RIO1 | PF01163.22 | 0.00088 | 1 | 1 |
ENSP00000397422 | RIO1 | PF01163.22 | 0.0012 | 1 | 1 |
Transcript ID | Name | Length | RefSeq ID | Protein ID | Length | RefSeq ID | UniportKB ID |
---|---|---|---|---|---|---|---|
ENST00000523583 | MAPK9-211 | 657 | - | ENSP00000430608 | 103 (aa) | - | E5RJ57 |
ENST00000393362 | MAPK9-204 | 1344 | - | ENSP00000377029 | 124 (aa) | - | D7R528 |
ENST00000393360 | MAPK9-203 | 4326 | XM_017009641 | ENSP00000377028 | 382 (aa) | XP_016865130 | P45984 |
ENST00000343111 | MAPK9-201 | 4369 | - | ENSP00000345524 | 382 (aa) | - | P45984 |
ENST00000452135 | MAPK9-207 | 4815 | XM_005265940 | ENSP00000394560 | 424 (aa) | XP_005265997 | P45984 |
ENST00000539014 | MAPK9-213 | 1668 | XM_017009643 | ENSP00000443149 | 214 (aa) | XP_016865132 | D7R525 |
ENST00000524170 | MAPK9-212 | 538 | - | - | - (aa) | - | - |
ENST00000347470 | MAPK9-202 | 1509 | - | ENSP00000321410 | 339 (aa) | - | J3KNK1 |
ENST00000425491 | MAPK9-206 | 2266 | - | ENSP00000397422 | 242 (aa) | - | P45984 |
ENST00000455781 | MAPK9-208 | 4336 | XM_017009638 | ENSP00000389338 | 424 (aa) | XP_016865127 | P45984 |
ENST00000397072 | MAPK9-205 | 1416 | - | ENSP00000380262 | 124 (aa) | - | D7R528 |
ENST00000523135 | MAPK9-210 | 372 | - | - | - (aa) | - | - |
ENST00000520212 | MAPK9-209 | 2395 | - | - | - (aa) | - | - |
Pathway ID | Pathway Name | Source |
---|---|---|
hsa01522 | Endocrine resistance | KEGG |
hsa04010 | MAPK signaling pathway | KEGG |
hsa04012 | ErbB signaling pathway | KEGG |
hsa04014 | Ras signaling pathway | KEGG |
hsa04024 | cAMP signaling pathway | KEGG |
hsa04068 | FoxO signaling pathway | KEGG |
hsa04071 | Sphingolipid signaling pathway | KEGG |
hsa04137 | Mitophagy - animal | KEGG |
hsa04140 | Autophagy - animal | KEGG |
hsa04141 | Protein processing in endoplasmic reticulum | KEGG |
hsa04210 | Apoptosis | KEGG |
hsa04215 | Apoptosis - multiple species | KEGG |
hsa04217 | Necroptosis | KEGG |
hsa04310 | Wnt signaling pathway | KEGG |
hsa04380 | Osteoclast differentiation | KEGG |
hsa04510 | Focal adhesion | KEGG |
hsa04530 | Tight junction | KEGG |
hsa04620 | Toll-like receptor signaling pathway | KEGG |
hsa04621 | NOD-like receptor signaling pathway | KEGG |
hsa04622 | RIG-I-like receptor signaling pathway | KEGG |
hsa04625 | C-type lectin receptor signaling pathway | KEGG |
hsa04657 | IL-17 signaling pathway | KEGG |
hsa04658 | Th1 and Th2 cell differentiation | KEGG |
hsa04659 | Th17 cell differentiation | KEGG |
hsa04660 | T cell receptor signaling pathway | KEGG |
hsa04664 | Fc epsilon RI signaling pathway | KEGG |
hsa04668 | TNF signaling pathway | KEGG |
hsa04722 | Neurotrophin signaling pathway | KEGG |
hsa04723 | Retrograde endocannabinoid signaling | KEGG |
hsa04728 | Dopaminergic synapse | KEGG |
hsa04750 | Inflammatory mediator regulation of TRP channels | KEGG |
hsa04910 | Insulin signaling pathway | KEGG |
hsa04912 | GnRH signaling pathway | KEGG |
hsa04914 | Progesterone-mediated oocyte maturation | KEGG |
hsa04917 | Prolactin signaling pathway | KEGG |
hsa04920 | Adipocytokine signaling pathway | KEGG |
hsa04926 | Relaxin signaling pathway | KEGG |
hsa04930 | Type II diabetes mellitus | KEGG |
hsa04931 | Insulin resistance | KEGG |
hsa04932 | Non-alcoholic fatty liver disease (NAFLD) | KEGG |
hsa04933 | AGE-RAGE signaling pathway in diabetic complications | KEGG |
hsa05120 | Epithelial cell signaling in Helicobacter pylori infection | KEGG |
hsa05131 | Shigellosis | KEGG |
hsa05132 | Salmonella infection | KEGG |
hsa05133 | Pertussis | KEGG |
hsa05142 | Chagas disease (American trypanosomiasis) | KEGG |
hsa05145 | Toxoplasmosis | KEGG |
hsa05152 | Tuberculosis | KEGG |
hsa05161 | Hepatitis B | KEGG |
hsa05162 | Measles | KEGG |
hsa05166 | Human T-cell leukemia virus 1 infection | KEGG |
hsa05167 | Kaposi sarcoma-associated herpesvirus infection | KEGG |
hsa05169 | Epstein-Barr virus infection | KEGG |
hsa05170 | Human immunodeficiency virus 1 infection | KEGG |
hsa05200 | Pathways in cancer | KEGG |
hsa05210 | Colorectal cancer | KEGG |
hsa05212 | Pancreatic cancer | KEGG |
hsa05231 | Choline metabolism in cancer | KEGG |
hsa05418 | Fluid shear stress and atherosclerosis | KEGG |
ensgID | SNP | Chromosome | Position | SNP-risk | Trait | PubmedID | 95% CI | Or or BEAT | EFO ID |
---|---|---|---|---|---|---|---|---|---|
ENSG00000050748 | rs13185784 | 5 | 180267068 | G | TRAIL levels | 27989323 | [0.049-0.12] SD units decrease | 0.0846 | EFO_0008300 |
Ensembl ID | Gene Symbol | Coverage | Identiy | Ortholog | Gene Symbol | Coverage | Identiy | Species |
---|---|---|---|---|---|---|---|---|
ENSG00000050748 | MAPK9 | 100 | 99.587 | ENSANAG00000024448 | MAPK9 | 100 | 99.587 | Aotus_nancymaae |
ENSG00000050748 | MAPK9 | 100 | 99.587 | ENSCJAG00000010293 | MAPK9 | 100 | 99.587 | Callithrix_jacchus |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSTSYG00000012099 | MAPK9 | 92 | 98.565 | Carlito_syrichta |
ENSG00000050748 | MAPK9 | 100 | 99.029 | ENSCCAG00000038038 | MAPK9 | 100 | 98.598 | Cebus_capucinus |
ENSG00000050748 | MAPK9 | 100 | 99.587 | ENSCATG00000033689 | MAPK9 | 100 | 99.587 | Cercocebus_atys |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSCANG00000028624 | MAPK9 | 100 | 100.000 | Colobus_angolensis_palliatus |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSFCAG00000025302 | MAPK9 | 99 | 98.122 | Felis_catus |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSGGOG00000016519 | MAPK9 | 100 | 100.000 | Gorilla_gorilla |
ENSG00000050748 | MAPK9 | 100 | 99.587 | ENSMFAG00000042461 | MAPK9 | 100 | 99.587 | Macaca_fascicularis |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSMLEG00000027658 | MAPK9 | 100 | 100.000 | Mandrillus_leucophaeus |
ENSG00000050748 | MAPK9 | 100 | 98.131 | ENSMICG00000015900 | MAPK9 | 100 | 98.131 | Microcebus_murinus |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSNLEG00000001965 | MAPK9 | 100 | 100.000 | Nomascus_leucogenys |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSODEG00000006074 | - | 99 | 100.000 | Octodon_degus |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSPPAG00000038007 | MAPK9 | 100 | 100.000 | Pan_paniscus |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSPPRG00000018998 | MAPK9 | 99 | 98.122 | Panthera_pardus |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSPTIG00000021236 | MAPK9 | 99 | 98.122 | Panthera_tigris_altaica |
ENSG00000050748 | MAPK9 | 100 | 100.000 | ENSPTRG00000017633 | MAPK9 | 100 | 100.000 | Pan_troglodytes |
ENSG00000050748 | MAPK9 | 100 | 99.587 | ENSPANG00000013251 | MAPK9 | 100 | 99.587 | Papio_anubis |
ENSG00000050748 | MAPK9 | 99 | 94.211 | ENSPCOG00000005660 | MAPK9 | 100 | 94.211 | Propithecus_coquereli |
ENSG00000050748 | MAPK9 | 83 | 99.005 | ENSRBIG00000027197 | MAPK9 | 100 | 100.000 | Rhinopithecus_bieti |
ENSG00000050748 | MAPK9 | 83 | 99.005 | ENSRROG00000027518 | MAPK9 | 100 | 100.000 | Rhinopithecus_roxellana |
ENSG00000050748 | MAPK9 | 100 | 99.587 | ENSSBOG00000019251 | MAPK9 | 100 | 99.587 | Saimiri_boliviensis_boliviensis |
Go ID | Go_term | PubmedID | Evidence | Category |
---|---|---|---|---|
GO:0004705 | JUN kinase activity | 8654373. | IDA | Function |
GO:0004707 | MAP kinase activity | 21873635. | IBA | Function |
GO:0004712 | protein serine/threonine/tyrosine kinase activity | - | IEA | Function |
GO:0005515 | protein binding | 10376527.15158451.16189514.16288922.19060904.20871632.21988832.25241761.25416956.28089251. | IPI | Function |
GO:0005524 | ATP binding | - | IEA | Function |
GO:0005634 | nucleus | 21873635. | IBA | Component |
GO:0005654 | nucleoplasm | - | TAS | Component |
GO:0005737 | cytoplasm | 21873635. | IBA | Component |
GO:0005739 | mitochondrion | - | IEA | Component |
GO:0005829 | cytosol | - | TAS | Component |
GO:0006468 | protein phosphorylation | 22441692. | IMP | Process |
GO:0007254 | JNK cascade | 8654373. | IDA | Process |
GO:0007254 | JNK cascade | - | TAS | Process |
GO:0007258 | JUN phosphorylation | - | IEA | Process |
GO:0008134 | transcription factor binding | 10376527. | IDA | Function |
GO:0009612 | response to mechanical stimulus | 21873635. | IBA | Process |
GO:0010468 | regulation of gene expression | 21873635. | IBA | Process |
GO:0010628 | positive regulation of gene expression | 18262097. | IMP | Process |
GO:0010744 | positive regulation of macrophage derived foam cell differentiation | 18262097. | IMP | Process |
GO:0018105 | peptidyl-serine phosphorylation | 21856198. | IDA | Process |
GO:0031398 | positive regulation of protein ubiquitination | - | IEA | Process |
GO:0034614 | cellular response to reactive oxygen species | 26514923. | IMP | Process |
GO:0035556 | intracellular signal transduction | 21873635. | IBA | Process |
GO:0038095 | Fc-epsilon receptor signaling pathway | - | TAS | Process |
GO:0042752 | regulation of circadian rhythm | - | ISS | Process |
GO:0043005 | neuron projection | 21873635. | IBA | Component |
GO:0043065 | positive regulation of apoptotic process | 21873635. | IBA | Process |
GO:0048511 | rhythmic process | - | IEA | Process |
GO:0048666 | neuron development | 21873635. | IBA | Process |
GO:0051090 | regulation of DNA-binding transcription factor activity | - | TAS | Process |
GO:0061833 | protein localization to tricellular tight junction | - | IEA | Process |
GO:0071276 | cellular response to cadmium ion | 26514923. | IMP | Process |
GO:0071310 | cellular response to organic substance | 21873635. | IBA | Process |
GO:0071803 | positive regulation of podosome assembly | - | IEA | Process |
GO:1901485 | positive regulation of transcription factor catabolic process | - | IEA | Process |
GO:2001235 | positive regulation of apoptotic signaling pathway | - | IEA | Process |
Cancer | Chr | Position | Mutation Type | dbSNP | Protein-change | Allele Freq | RBD |
---|---|---|---|---|---|---|---|
BLCA | |||||||
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COAD | |||||||
ESCA | |||||||
ESCA | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
GBM | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
HNSC | |||||||
LAML | |||||||
LAML | |||||||
LGG | |||||||
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LIHC | |||||||
LIHC | |||||||
LIHC | |||||||
LUAD | |||||||
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LUAD | |||||||
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LUAD | |||||||
LUSC | |||||||
LUSC | |||||||
OV | |||||||
OV | |||||||
PAAD | |||||||
PAAD | |||||||
READ | |||||||
READ | |||||||
READ | |||||||
READ | |||||||
SARC | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
SKCM | |||||||
STAD | |||||||
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UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
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UCEC | |||||||
UCEC | |||||||
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UCEC | |||||||
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UCEC | |||||||
UCEC | |||||||
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UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
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UCEC | |||||||
UCEC | |||||||
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UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCEC | |||||||
UCS |
Cancer | Type | Freq | Q-value |
---|---|---|---|
KIRC | |||
KIRP | |||
KIRP | |||
LUAD | |||
LUSC | |||
MESO | |||
PRAD | |||
SKCM | |||
THCA |
Cancer | P-value | Q-value |
---|---|---|
KIRC | ||
ACC | ||
UCS | ||
HNSC | ||
SKCM | ||
LUSC | ||
ESCA | ||
COAD | ||
READ | ||
LIHC | ||
LGG | ||
THCA |