EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000055044 (Gene tree)
Gene ID: 51602
Gene Symbol: NOP58
Alias: NOP5|HSPC120
Full Name: NOP58 ribonucleoprotein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 37,951 bases
Position: chr2:202,265,716-202,303,666
Accession: 29926
RBP type: canonical RBP
Summary: The protein encoded by this gene is a core component of box C/D small nucleolar ribonucleoproteins. Some box C/D small nucleolar RNAs (snoRNAs), such as U3, U8, and U14, are dependent upon the encoded protein for their synthesis. This protein is SUMOylated, which is necessary for high affinity binding to snoRNAs. [provided by RefSeq, Nov 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000264279	Nop	PF01798.18	1.3e-83	1	1
ENSP00000264279	NOP5NT	PF08156.13	8.4e-23	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
11839271	Archaeal guide RNAs function in rRNA modification in the eukaryotic nucleus.	Curr Biol	2002 Feb 5	Speckmann WA	-
16949610	Assembly of the archaeal box C/D sRNP can occur via alternative pathways and requires temperature-facilitated sRNA remodeling.	J Mol Biol	2006 Oct 6	Gagnon KT	-
20962039	A novel Nop5-sRNA interaction that is required for efficient archaeal box C/D sRNP formation.	RNA	2010 Dec	Ghalei H	doi: 10.1261/rna.2380410

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000472050	NOP58-205	582	-	-	- (aa)	-	-
ENST00000433543	NOP58-203	714	-	ENSP00000388126	187 (aa)	-	H7BZ72
ENST00000478941	NOP58-207	508	-	-	- (aa)	-	-
ENST00000492688	NOP58-209	571	-	-	- (aa)	-	-
ENST00000488403	NOP58-208	871	-	-	- (aa)	-	-
ENST00000426814	NOP58-202	655	-	ENSP00000388905	68 (aa)	-	F8WED0
ENST00000478508	NOP58-206	599	-	-	- (aa)	-	-
ENST00000467734	NOP58-204	638	-	-	- (aa)	-	-
ENST00000264279	NOP58-201	2046	-	ENSP00000264279	529 (aa)	-	Q9Y2X3
ENST00000492740	NOP58-210	793	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000055044's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000055044	rs4470328	2	202299026	?	Mean corpuscular hemoglobin	30595370			EFO_0004527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000055044's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000055044	NOP58	87	49.704	ENSG00000101361	NOP56	91	35.741

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000055044	NOP58	91	81.287	ENSAPOG00000002127	nop58	84	79.295	Acanthochromis_polyacanthus
ENSG00000055044	NOP58	87	45.509	ENSAPOG00000002789	nop56	98	37.381	Acanthochromis_polyacanthus
ENSG00000055044	NOP58	100	94.434	ENSAMEG00000013168	NOP58	100	94.434	Ailuropoda_melanoleuca
ENSG00000055044	NOP58	87	49.102	ENSAMEG00000011299	NOP56	88	37.300	Ailuropoda_melanoleuca
ENSG00000055044	NOP58	87	46.108	ENSACIG00000018402	nop56	85	40.044	Amphilophus_citrinellus
ENSG00000055044	NOP58	91	83.626	ENSACIG00000021773	nop58	95	80.574	Amphilophus_citrinellus
ENSG00000055044	NOP58	91	81.287	ENSAOCG00000002571	nop58	87	78.337	Amphiprion_ocellaris
ENSG00000055044	NOP58	91	81.287	ENSAPEG00000010178	nop58	85	78.337	Amphiprion_percula
ENSG00000055044	NOP58	87	45.509	ENSAPEG00000002707	nop56	88	37.667	Amphiprion_percula
ENSG00000055044	NOP58	87	44.910	ENSATEG00000023695	nop56	87	37.653	Anabas_testudineus
ENSG00000055044	NOP58	91	82.456	ENSATEG00000009794	nop58	85	78.993	Anabas_testudineus
ENSG00000055044	NOP58	91	87.647	ENSAPLG00000008524	NOP58	94	80.132	Anas_platyrhynchos
ENSG00000055044	NOP58	87	91.525	ENSACAG00000005194	NOP58	99	82.270	Anolis_carolinensis
ENSG00000055044	NOP58	87	47.305	ENSACAG00000005783	NOP56	74	43.810	Anolis_carolinensis
ENSG00000055044	NOP58	100	97.566	ENSANAG00000037044	NOP58	99	99.572	Aotus_nancymaae
ENSG00000055044	NOP58	87	46.108	ENSACLG00000012153	nop56	89	39.105	Astatotilapia_calliptera
ENSG00000055044	NOP58	91	83.626	ENSACLG00000024979	nop58	86	80.795	Astatotilapia_calliptera
ENSG00000055044	NOP58	91	83.626	ENSAMXG00000005022	nop58	96	75.591	Astyanax_mexicanus
ENSG00000055044	NOP58	87	46.707	ENSAMXG00000008041	nop56	67	43.902	Astyanax_mexicanus
ENSG00000055044	NOP58	87	49.701	ENSBTAG00000018812	NOP56	68	44.686	Bos_taurus
ENSG00000055044	NOP58	100	94.991	ENSBTAG00000005517	NOP58	100	94.991	Bos_taurus
ENSG00000055044	NOP58	87	41.176	WBGene00010627	K07C5.4	83	40.441	Caenorhabditis_elegans
ENSG00000055044	NOP58	90	63.905	WBGene00020915	nol-5	95	55.889	Caenorhabditis_elegans
ENSG00000055044	NOP58	100	97.368	ENSCJAG00000004985	NOP58	99	98.929	Callithrix_jacchus
ENSG00000055044	NOP58	100	96.296	ENSCAFG00000012448	NOP58	100	96.296	Canis_familiaris
ENSG00000055044	NOP58	87	49.102	ENSCAFG00000006651	NOP56	68	44.444	Canis_familiaris
ENSG00000055044	NOP58	100	96.296	ENSCAFG00020002394	-	100	96.296	Canis_lupus_dingo
ENSG00000055044	NOP58	87	49.102	ENSCAFG00020003577	NOP56	68	44.444	Canis_lupus_dingo
ENSG00000055044	NOP58	85	100.000	ENSCAFG00020010952	-	97	100.000	Canis_lupus_dingo
ENSG00000055044	NOP58	97	94.434	ENSCHIG00000025013	NOP58	94	94.434	Capra_hircus
ENSG00000055044	NOP58	87	49.701	ENSCHIG00000023450	NOP56	68	44.686	Capra_hircus
ENSG00000055044	NOP58	100	96.786	ENSTSYG00000006007	NOP58	100	96.786	Carlito_syrichta
ENSG00000055044	NOP58	87	49.102	ENSTSYG00000026366	NOP56	68	44.444	Carlito_syrichta
ENSG00000055044	NOP58	92	86.047	ENSCAPG00000013150	NOP58	100	79.029	Cavia_aperea
ENSG00000055044	NOP58	87	49.102	ENSCPOG00000015315	NOP56	86	39.744	Cavia_porcellus
ENSG00000055044	NOP58	94	92.188	ENSCPOG00000030510	NOP58	100	90.093	Cavia_porcellus
ENSG00000055044	NOP58	100	98.113	ENSCCAG00000021573	NOP58	100	98.113	Cebus_capucinus
ENSG00000055044	NOP58	87	49.102	ENSCATG00000031167	NOP56	68	44.444	Cercocebus_atys
ENSG00000055044	NOP58	100	99.057	ENSCATG00000037684	NOP58	100	99.057	Cercocebus_atys
ENSG00000055044	NOP58	87	49.102	ENSCLAG00000013816	NOP56	68	44.686	Chinchilla_lanigera
ENSG00000055044	NOP58	100	95.693	ENSCLAG00000003819	NOP58	100	95.693	Chinchilla_lanigera
ENSG00000055044	NOP58	92	100.000	ENSCSAG00000010496	NOP58	99	99.786	Chlorocebus_sabaeus
ENSG00000055044	NOP58	87	49.102	ENSCSAG00000010955	NOP56	68	44.444	Chlorocebus_sabaeus
ENSG00000055044	NOP58	82	45.912	ENSCHOG00000001185	NOP56	70	34.524	Choloepus_hoffmanni
ENSG00000055044	NOP58	97	72.374	ENSCHOG00000011655	NOP58	100	72.374	Choloepus_hoffmanni
ENSG00000055044	NOP58	91	87.059	ENSCPBG00000011565	NOP58	87	81.182	Chrysemys_picta_bellii
ENSG00000055044	NOP58	87	47.904	ENSCPBG00000024420	NOP56	64	45.902	Chrysemys_picta_bellii
ENSG00000055044	NOP58	89	45.029	ENSCING00000019946	-	73	41.404	Ciona_intestinalis
ENSG00000055044	NOP58	91	73.529	ENSCING00000005462	-	84	67.401	Ciona_intestinalis
ENSG00000055044	NOP58	86	65.000	ENSCSAVG00000004558	-	100	62.914	Ciona_savignyi
ENSG00000055044	NOP58	100	95.094	ENSCANG00000010294	NOP58	100	95.094	Colobus_angolensis_palliatus
ENSG00000055044	NOP58	87	49.102	ENSCANG00000039026	NOP56	68	44.444	Colobus_angolensis_palliatus
ENSG00000055044	NOP58	100	93.494	ENSCGRG00001017869	Nop58	100	94.186	Cricetulus_griseus_chok1gshd
ENSG00000055044	NOP58	87	49.102	ENSCGRG00001019528	Nop56	68	43.961	Cricetulus_griseus_chok1gshd
ENSG00000055044	NOP58	100	94.371	ENSCGRG00000006262	Nop58	100	94.371	Cricetulus_griseus_crigri
ENSG00000055044	NOP58	87	44.910	ENSCSEG00000007169	nop56	72	43.276	Cynoglossus_semilaevis
ENSG00000055044	NOP58	91	82.941	ENSCSEG00000004382	nop58	89	79.333	Cynoglossus_semilaevis
ENSG00000055044	NOP58	91	80.702	ENSCVAG00000011580	nop58	98	81.327	Cyprinodon_variegatus
ENSG00000055044	NOP58	87	44.910	ENSCVAG00000017690	nop56	97	38.113	Cyprinodon_variegatus
ENSG00000055044	NOP58	91	84.706	ENSDARG00000104353	nop58	100	78.431	Danio_rerio
ENSG00000055044	NOP58	87	47.093	ENSDARG00000012820	nop56	75	56.627	Danio_rerio
ENSG00000055044	NOP58	100	96.053	ENSDNOG00000002285	NOP58	100	96.053	Dasypus_novemcinctus
ENSG00000055044	NOP58	87	48.503	ENSDNOG00000042962	NOP56	66	44.203	Dasypus_novemcinctus
ENSG00000055044	NOP58	91	70.588	FBgn0026196	nop5	87	66.517	Drosophila_melanogaster
ENSG00000055044	NOP58	87	49.102	ENSETEG00000015951	NOP56	67	44.634	Echinops_telfairi
ENSG00000055044	NOP58	84	98.726	ENSETEG00000002057	NOP58	100	81.509	Echinops_telfairi
ENSG00000055044	NOP58	75	80.392	ENSEBUG00000010545	nop58	96	70.498	Eptatretus_burgeri
ENSG00000055044	NOP58	87	43.713	ENSEBUG00000004487	nop56	75	42.651	Eptatretus_burgeri
ENSG00000055044	NOP58	100	96.067	ENSEASG00005002393	NOP58	100	96.067	Equus_asinus_asinus
ENSG00000055044	NOP58	87	49.102	ENSEASG00005012996	NOP56	68	44.444	Equus_asinus_asinus
ENSG00000055044	NOP58	100	96.255	ENSECAG00000024696	NOP58	100	96.255	Equus_caballus
ENSG00000055044	NOP58	87	49.102	ENSECAG00000021299	NOP56	78	44.444	Equus_caballus
ENSG00000055044	NOP58	100	81.853	ENSEEUG00000015752	-	100	81.474	Erinaceus_europaeus
ENSG00000055044	NOP58	87	49.701	ENSEEUG00000001677	NOP56	69	45.169	Erinaceus_europaeus
ENSG00000055044	NOP58	91	82.456	ENSELUG00000002860	nop58	91	81.560	Esox_lucius
ENSG00000055044	NOP58	87	49.704	ENSFCAG00000014450	NOP56	68	44.444	Felis_catus
ENSG00000055044	NOP58	100	94.727	ENSFCAG00000014093	NOP58	100	94.727	Felis_catus
ENSG00000055044	NOP58	87	44.910	ENSFALG00000008947	NOP56	87	41.138	Ficedula_albicollis
ENSG00000055044	NOP58	87	93.220	ENSFALG00000004052	NOP58	89	82.340	Ficedula_albicollis
ENSG00000055044	NOP58	96	65.029	ENSFDAG00000013317	-	98	65.226	Fukomys_damarensis
ENSG00000055044	NOP58	100	93.621	ENSFDAG00000010143	-	100	94.747	Fukomys_damarensis
ENSG00000055044	NOP58	87	49.102	ENSFDAG00000007422	NOP56	89	37.611	Fukomys_damarensis
ENSG00000055044	NOP58	91	83.529	ENSFHEG00000008065	nop58	98	81.030	Fundulus_heteroclitus
ENSG00000055044	NOP58	87	44.910	ENSFHEG00000003342	nop56	99	38.380	Fundulus_heteroclitus
ENSG00000055044	NOP58	91	82.456	ENSGMOG00000003570	nop58	85	79.295	Gadus_morhua
ENSG00000055044	NOP58	87	46.108	ENSGMOG00000008776	nop56	76	43.873	Gadus_morhua
ENSG00000055044	NOP58	88	47.024	ENSGALG00000032730	NOP56	57	45.297	Gallus_gallus
ENSG00000055044	NOP58	87	93.220	ENSGALG00000008454	NOP58	86	82.119	Gallus_gallus
ENSG00000055044	NOP58	76	86.538	ENSGAFG00000015066	nop58	93	72.600	Gambusia_affinis
ENSG00000055044	NOP58	87	44.311	ENSGAFG00000021506	nop56	76	42.054	Gambusia_affinis
ENSG00000055044	NOP58	96	37.812	ENSGACG00000008815	nop56	76	42.683	Gasterosteus_aculeatus
ENSG00000055044	NOP58	91	80.702	ENSGACG00000013746	nop58	86	77.533	Gasterosteus_aculeatus
ENSG00000055044	NOP58	87	48.810	ENSGAGG00000004324	NOP56	75	43.812	Gopherus_agassizii
ENSG00000055044	NOP58	91	87.059	ENSGAGG00000024049	NOP58	88	81.457	Gopherus_agassizii
ENSG00000055044	NOP58	87	49.704	ENSGGOG00000002886	NOP56	68	44.444	Gorilla_gorilla
ENSG00000055044	NOP58	94	92.188	ENSGGOG00000014545	-	100	69.159	Gorilla_gorilla
ENSG00000055044	NOP58	87	46.108	ENSHBUG00000021495	nop56	76	43.622	Haplochromis_burtoni
ENSG00000055044	NOP58	91	83.626	ENSHBUG00000021827	nop58	85	80.795	Haplochromis_burtoni
ENSG00000055044	NOP58	92	93.023	ENSHGLG00000000430	-	100	83.365	Heterocephalus_glaber_female
ENSG00000055044	NOP58	90	75.595	ENSHGLG00000019315	-	92	70.588	Heterocephalus_glaber_female
ENSG00000055044	NOP58	90	95.082	ENSHGLG00000015648	-	72	100.000	Heterocephalus_glaber_female
ENSG00000055044	NOP58	100	95.327	ENSHGLG00000011278	-	100	95.327	Heterocephalus_glaber_female
ENSG00000055044	NOP58	90	75.595	ENSHGLG00100001097	-	89	67.770	Heterocephalus_glaber_male
ENSG00000055044	NOP58	94	89.062	ENSHGLG00100009239	-	100	80.377	Heterocephalus_glaber_male
ENSG00000055044	NOP58	100	95.327	ENSHGLG00100007782	-	100	95.327	Heterocephalus_glaber_male
ENSG00000055044	NOP58	90	95.082	ENSHGLG00100011251	-	72	100.000	Heterocephalus_glaber_male
ENSG00000055044	NOP58	91	85.380	ENSHCOG00000012934	nop58	94	74.449	Hippocampus_comes
ENSG00000055044	NOP58	87	44.643	ENSHCOG00000012649	nop56	74	43.032	Hippocampus_comes
ENSG00000055044	NOP58	87	46.707	ENSIPUG00000011024	nop56	89	39.406	Ictalurus_punctatus
ENSG00000055044	NOP58	91	83.041	ENSIPUG00000020953	nop58	82	79.956	Ictalurus_punctatus
ENSG00000055044	NOP58	100	96.415	ENSSTOG00000006155	NOP58	100	96.415	Ictidomys_tridecemlineatus
ENSG00000055044	NOP58	87	49.701	ENSSTOG00000012503	NOP56	68	44.928	Ictidomys_tridecemlineatus
ENSG00000055044	NOP58	100	88.993	ENSJJAG00000018213	Nop58	100	90.299	Jaculus_jaculus
ENSG00000055044	NOP58	91	84.211	ENSKMAG00000000838	nop58	82	80.306	Kryptolebias_marmoratus
ENSG00000055044	NOP58	87	45.509	ENSKMAG00000019440	nop56	72	43.457	Kryptolebias_marmoratus
ENSG00000055044	NOP58	91	82.456	ENSLBEG00000009054	nop58	85	78.775	Labrus_bergylta
ENSG00000055044	NOP58	87	46.108	ENSLBEG00000000743	nop56	98	38.544	Labrus_bergylta
ENSG00000055044	NOP58	91	87.059	ENSLACG00000014882	NOP58	85	83.040	Latimeria_chalumnae
ENSG00000055044	NOP58	87	30.460	ENSLACG00000011293	NOP56	72	36.957	Latimeria_chalumnae
ENSG00000055044	NOP58	91	83.626	ENSLOCG00000010225	nop58	86	81.678	Lepisosteus_oculatus
ENSG00000055044	NOP58	97	94.605	ENSLAFG00000015568	NOP58	100	95.183	Loxodonta_africana
ENSG00000055044	NOP58	87	49.704	ENSLAFG00000001406	NOP56	68	44.146	Loxodonta_africana
ENSG00000055044	NOP58	87	49.102	ENSMFAG00000041293	NOP56	68	44.444	Macaca_fascicularis
ENSG00000055044	NOP58	100	99.434	ENSMFAG00000036935	NOP58	100	99.434	Macaca_fascicularis
ENSG00000055044	NOP58	100	99.434	ENSMMUG00000000582	NOP58	100	99.434	Macaca_mulatta
ENSG00000055044	NOP58	87	49.102	ENSMMUG00000013888	NOP56	68	44.444	Macaca_mulatta
ENSG00000055044	NOP58	100	99.434	ENSMNEG00000012760	NOP58	100	99.434	Macaca_nemestrina
ENSG00000055044	NOP58	87	49.102	ENSMNEG00000033186	NOP56	68	44.444	Macaca_nemestrina
ENSG00000055044	NOP58	100	99.434	ENSMLEG00000038485	NOP58	100	99.434	Mandrillus_leucophaeus
ENSG00000055044	NOP58	87	49.102	ENSMLEG00000020816	NOP56	68	44.444	Mandrillus_leucophaeus
ENSG00000055044	NOP58	91	83.626	ENSMAMG00000009967	nop58	85	79.167	Mastacembelus_armatus
ENSG00000055044	NOP58	91	83.626	ENSMZEG00005000668	nop58	86	80.795	Maylandia_zebra
ENSG00000055044	NOP58	87	46.108	ENSMZEG00005026863	nop56	89	39.105	Maylandia_zebra
ENSG00000055044	NOP58	91	87.647	ENSMGAG00000008189	NOP58	82	80.574	Meleagris_gallopavo
ENSG00000055044	NOP58	87	47.904	ENSMGAG00000007493	-	96	46.847	Meleagris_gallopavo
ENSG00000055044	NOP58	87	49.102	ENSMAUG00000021793	Nop56	68	43.961	Mesocricetus_auratus
ENSG00000055044	NOP58	100	94.041	ENSMAUG00000009734	Nop58	100	93.669	Mesocricetus_auratus
ENSG00000055044	NOP58	100	97.543	ENSMICG00000003539	-	99	98.929	Microcebus_murinus
ENSG00000055044	NOP58	94	82.812	ENSMICG00000028354	-	95	72.300	Microcebus_murinus
ENSG00000055044	NOP58	87	49.102	ENSMICG00000016553	NOP56	85	44.686	Microcebus_murinus
ENSG00000055044	NOP58	100	94.063	ENSMOCG00000007756	Nop58	100	94.063	Microtus_ochrogaster
ENSG00000055044	NOP58	91	83.529	ENSMMOG00000004350	nop58	95	80.425	Mola_mola
ENSG00000055044	NOP58	87	45.562	ENSMMOG00000012293	nop56	74	43.223	Mola_mola
ENSG00000055044	NOP58	91	92.353	ENSMODG00000016294	NOP58	99	81.818	Monodelphis_domestica
ENSG00000055044	NOP58	87	47.305	ENSMODG00000005184	NOP56	75	42.998	Monodelphis_domestica
ENSG00000055044	NOP58	96	39.695	ENSMALG00000001868	nop56	99	37.996	Monopterus_albus
ENSG00000055044	NOP58	91	83.626	ENSMALG00000013001	nop58	86	78.556	Monopterus_albus
ENSG00000055044	NOP58	100	96.791	MGP_CAROLIEiJ_G0014181	Nop58	97	100.000	Mus_caroli
ENSG00000055044	NOP58	87	48.503	MGP_CAROLIEiJ_G0024295	Nop56	94	43.220	Mus_caroli
ENSG00000055044	NOP58	87	48.503	ENSMUSG00000027405	Nop56	93	43.220	Mus_musculus
ENSG00000055044	NOP58	100	96.257	ENSMUSG00000026020	Nop58	97	100.000	Mus_musculus
ENSG00000055044	NOP58	87	48.503	MGP_PahariEiJ_G0025740	Nop56	94	43.220	Mus_pahari
ENSG00000055044	NOP58	100	96.791	MGP_PahariEiJ_G0027419	Nop58	97	100.000	Mus_pahari
ENSG00000055044	NOP58	87	48.503	MGP_SPRETEiJ_G0025215	Nop56	94	43.220	Mus_spretus
ENSG00000055044	NOP58	100	96.257	MGP_SPRETEiJ_G0014988	Nop58	97	100.000	Mus_spretus
ENSG00000055044	NOP58	100	95.547	ENSMPUG00000000351	NOP58	100	95.547	Mustela_putorius_furo
ENSG00000055044	NOP58	87	50.299	ENSMLUG00000027085	NOP56	92	38.698	Myotis_lucifugus
ENSG00000055044	NOP58	100	92.007	ENSMLUG00000006896	NOP58	100	94.424	Myotis_lucifugus
ENSG00000055044	NOP58	100	95.896	ENSNGAG00000016443	Nop58	100	95.896	Nannospalax_galili
ENSG00000055044	NOP58	91	83.041	ENSNBRG00000002165	nop58	95	72.406	Neolamprologus_brichardi
ENSG00000055044	NOP58	87	45.509	ENSNBRG00000018384	nop56	89	38.330	Neolamprologus_brichardi
ENSG00000055044	NOP58	87	49.102	ENSNLEG00000009178	NOP56	68	44.444	Nomascus_leucogenys
ENSG00000055044	NOP58	100	99.057	ENSNLEG00000007000	NOP58	100	99.057	Nomascus_leucogenys
ENSG00000055044	NOP58	63	97.674	ENSMEUG00000000706	-	52	97.674	Notamacropus_eugenii
ENSG00000055044	NOP58	87	49.405	ENSMEUG00000002202	NOP56	77	43.873	Notamacropus_eugenii
ENSG00000055044	NOP58	87	49.704	ENSOPRG00000007520	NOP56	68	44.444	Ochotona_princeps
ENSG00000055044	NOP58	99	96.591	ENSOPRG00000000129	NOP58	99	96.591	Ochotona_princeps
ENSG00000055044	NOP58	94	92.188	ENSODEG00000010151	NOP58	100	85.421	Octodon_degus
ENSG00000055044	NOP58	91	82.456	ENSONIG00000013196	nop58	84	79.912	Oreochromis_niloticus
ENSG00000055044	NOP58	90	87.574	ENSOANG00000002420	NOP58	84	83.526	Ornithorhynchus_anatinus
ENSG00000055044	NOP58	87	40.571	ENSOANG00000000505	NOP56	75	39.903	Ornithorhynchus_anatinus
ENSG00000055044	NOP58	100	93.208	ENSOCUG00000003631	NOP58	100	92.264	Oryctolagus_cuniculus
ENSG00000055044	NOP58	87	50.296	ENSOCUG00000014960	NOP56	83	40.557	Oryctolagus_cuniculus
ENSG00000055044	NOP58	87	47.619	ENSORLG00000008833	nop56	70	44.010	Oryzias_latipes
ENSG00000055044	NOP58	91	81.871	ENSORLG00000003162	nop58	85	79.249	Oryzias_latipes
ENSG00000055044	NOP58	87	47.619	ENSORLG00020008608	nop56	70	44.010	Oryzias_latipes_hni
ENSG00000055044	NOP58	91	81.871	ENSORLG00020021117	nop58	85	79.249	Oryzias_latipes_hni
ENSG00000055044	NOP58	87	47.619	ENSORLG00015004262	nop56	70	44.010	Oryzias_latipes_hsok
ENSG00000055044	NOP58	91	81.871	ENSORLG00015020890	nop58	85	79.249	Oryzias_latipes_hsok
ENSG00000055044	NOP58	87	47.619	ENSOMEG00000002458	nop56	71	44.010	Oryzias_melastigma
ENSG00000055044	NOP58	91	72.515	ENSOMEG00000000641	nop58	95	75.650	Oryzias_melastigma
ENSG00000055044	NOP58	87	49.102	ENSOGAG00000004681	NOP56	65	44.819	Otolemur_garnettii
ENSG00000055044	NOP58	100	97.543	ENSOGAG00000003906	NOP58	100	97.543	Otolemur_garnettii
ENSG00000055044	NOP58	87	49.701	ENSOARG00000006470	NOP56	68	44.258	Ovis_aries
ENSG00000055044	NOP58	99	95.140	ENSOARG00000017569	NOP58	100	95.140	Ovis_aries
ENSG00000055044	NOP58	97	99.805	ENSPPAG00000036626	NOP58	100	99.611	Pan_paniscus
ENSG00000055044	NOP58	87	49.704	ENSPPAG00000027513	NOP56	68	44.444	Pan_paniscus
ENSG00000055044	NOP58	100	96.998	ENSPPRG00000013837	NOP58	100	96.998	Panthera_pardus
ENSG00000055044	NOP58	87	49.704	ENSPPRG00000004623	NOP56	68	44.444	Panthera_pardus
ENSG00000055044	NOP58	100	95.564	ENSPTIG00000013131	NOP58	100	95.564	Panthera_tigris_altaica
ENSG00000055044	NOP58	87	49.704	ENSPTIG00000012828	NOP56	63	45.745	Panthera_tigris_altaica
ENSG00000055044	NOP58	100	99.433	ENSPTRG00000012818	NOP58	100	99.433	Pan_troglodytes
ENSG00000055044	NOP58	87	49.704	ENSPTRG00000013179	NOP56	68	44.444	Pan_troglodytes
ENSG00000055044	NOP58	97	95.192	ENSPANG00000005211	NOP58	97	95.192	Papio_anubis
ENSG00000055044	NOP58	87	49.102	ENSPANG00000023584	NOP56	68	44.444	Papio_anubis
ENSG00000055044	NOP58	87	46.707	ENSPKIG00000017104	nop56	75	44.010	Paramormyrops_kingsleyae
ENSG00000055044	NOP58	87	34.940	ENSPKIG00000016095	-	80	34.615	Paramormyrops_kingsleyae
ENSG00000055044	NOP58	91	84.211	ENSPKIG00000003585	nop58	86	80.525	Paramormyrops_kingsleyae
ENSG00000055044	NOP58	87	47.904	ENSPSIG00000006680	NOP56	73	47.411	Pelodiscus_sinensis
ENSG00000055044	NOP58	91	87.059	ENSPSIG00000011773	NOP58	85	79.431	Pelodiscus_sinensis
ENSG00000055044	NOP58	87	45.509	ENSPMGG00000013259	nop56	80	43.112	Periophthalmus_magnuspinnatus
ENSG00000055044	NOP58	91	82.353	ENSPMGG00000015380	nop58	89	79.956	Periophthalmus_magnuspinnatus
ENSG00000055044	NOP58	92	98.256	ENSPEMG00000023262	-	99	86.252	Peromyscus_maniculatus_bairdii
ENSG00000055044	NOP58	100	93.889	ENSPEMG00000021263	-	100	93.889	Peromyscus_maniculatus_bairdii
ENSG00000055044	NOP58	99	38.776	ENSPMAG00000003197	nop56	75	44.039	Petromyzon_marinus
ENSG00000055044	NOP58	91	91.765	ENSPCIG00000008839	NOP58	99	81.921	Phascolarctos_cinereus
ENSG00000055044	NOP58	87	48.810	ENSPCIG00000005997	NOP56	75	43.627	Phascolarctos_cinereus
ENSG00000055044	NOP58	91	82.456	ENSPFOG00000004114	nop58	96	77.197	Poecilia_formosa
ENSG00000055044	NOP58	87	44.910	ENSPFOG00000009713	nop56	76	42.543	Poecilia_formosa
ENSG00000055044	NOP58	91	82.456	ENSPLAG00000004466	nop58	94	81.087	Poecilia_latipinna
ENSG00000055044	NOP58	87	44.910	ENSPLAG00000012463	nop56	76	42.543	Poecilia_latipinna
ENSG00000055044	NOP58	91	82.456	ENSPMEG00000007061	nop58	94	81.087	Poecilia_mexicana
ENSG00000055044	NOP58	87	44.910	ENSPMEG00000015210	nop56	76	42.543	Poecilia_mexicana
ENSG00000055044	NOP58	91	81.871	ENSPREG00000014125	nop58	93	80.896	Poecilia_reticulata
ENSG00000055044	NOP58	87	44.311	ENSPREG00000021077	nop56	76	42.543	Poecilia_reticulata
ENSG00000055044	NOP58	87	49.704	ENSPPYG00000010838	NOP56	90	37.390	Pongo_abelii
ENSG00000055044	NOP58	92	100.000	ENSPPYG00000013084	NOP58	100	80.189	Pongo_abelii
ENSG00000055044	NOP58	87	49.701	ENSPCAG00000012869	NOP56	64	45.641	Procavia_capensis
ENSG00000055044	NOP58	100	85.472	ENSPCAG00000006910	NOP58	99	85.472	Procavia_capensis
ENSG00000055044	NOP58	87	49.102	ENSPCOG00000024681	NOP56	67	44.444	Propithecus_coquereli
ENSG00000055044	NOP58	94	92.188	ENSPCOG00000006096	-	86	99.010	Propithecus_coquereli
ENSG00000055044	NOP58	94	92.188	ENSPVAG00000002307	NOP58	100	81.285	Pteropus_vampyrus
ENSG00000055044	NOP58	87	49.102	ENSPVAG00000017030	NOP56	83	39.563	Pteropus_vampyrus
ENSG00000055044	NOP58	91	83.626	ENSPNYG00000019200	nop58	85	80.795	Pundamilia_nyererei
ENSG00000055044	NOP58	87	46.108	ENSPNYG00000003860	nop56	71	44.010	Pundamilia_nyererei
ENSG00000055044	NOP58	87	46.707	ENSPNAG00000023364	nop56	79	44.146	Pygocentrus_nattereri
ENSG00000055044	NOP58	91	83.041	ENSPNAG00000022346	nop58	86	77.007	Pygocentrus_nattereri
ENSG00000055044	NOP58	100	94.757	ENSRNOG00000016486	Nop58	100	94.757	Rattus_norvegicus
ENSG00000055044	NOP58	87	49.102	ENSRNOG00000007128	Nop56	69	43.961	Rattus_norvegicus
ENSG00000055044	NOP58	94	92.188	ENSRBIG00000043924	NOP58	100	81.509	Rhinopithecus_bieti
ENSG00000055044	NOP58	87	49.102	ENSRBIG00000030689	NOP56	78	44.444	Rhinopithecus_bieti
ENSG00000055044	NOP58	87	49.102	ENSRROG00000020071	NOP56	68	44.444	Rhinopithecus_roxellana
ENSG00000055044	NOP58	100	99.434	ENSRROG00000038002	NOP58	100	99.434	Rhinopithecus_roxellana
ENSG00000055044	NOP58	87	44.643	YLR197W	NOP56	91	40.340	Saccharomyces_cerevisiae
ENSG00000055044	NOP58	90	60.355	YOR310C	NOP58	90	49.458	Saccharomyces_cerevisiae
ENSG00000055044	NOP58	100	93.045	ENSSBOG00000020494	NOP58	100	93.045	Saimiri_boliviensis_boliviensis
ENSG00000055044	NOP58	87	48.503	ENSSHAG00000017162	NOP56	75	43.243	Sarcophilus_harrisii
ENSG00000055044	NOP58	91	92.353	ENSSHAG00000011398	NOP58	83	86.907	Sarcophilus_harrisii
ENSG00000055044	NOP58	87	43.713	ENSSFOG00015010930	nop56	72	44.472	Scleropages_formosus
ENSG00000055044	NOP58	91	83.041	ENSSFOG00015017870	nop58	85	80.744	Scleropages_formosus
ENSG00000055044	NOP58	87	46.154	ENSSMAG00000009454	nop56	96	37.593	Scophthalmus_maximus
ENSG00000055044	NOP58	91	81.287	ENSSMAG00000000270	nop58	100	72.316	Scophthalmus_maximus
ENSG00000055044	NOP58	91	81.287	ENSSDUG00000008035	nop58	94	80.615	Seriola_dumerili
ENSG00000055044	NOP58	87	46.108	ENSSDUG00000022526	nop56	91	38.654	Seriola_dumerili
ENSG00000055044	NOP58	91	81.287	ENSSLDG00000020773	nop58	94	78.855	Seriola_lalandi_dorsalis
ENSG00000055044	NOP58	87	46.108	ENSSLDG00000018177	nop56	96	37.613	Seriola_lalandi_dorsalis
ENSG00000055044	NOP58	100	92.060	ENSSARG00000013004	NOP58	100	92.060	Sorex_araneus
ENSG00000055044	NOP58	91	87.647	ENSSPUG00000003921	NOP58	88	82.243	Sphenodon_punctatus
ENSG00000055044	NOP58	87	49.405	ENSSPUG00000001535	NOP56	74	44.417	Sphenodon_punctatus
ENSG00000055044	NOP58	87	45.509	ENSSPAG00000018480	nop56	82	40.275	Stegastes_partitus
ENSG00000055044	NOP58	91	81.871	ENSSPAG00000022513	nop58	90	75.717	Stegastes_partitus
ENSG00000055044	NOP58	87	49.102	ENSSSCG00000027676	NOP56	68	44.444	Sus_scrofa
ENSG00000055044	NOP58	100	95.531	ENSSSCG00000022225	NOP58	100	95.531	Sus_scrofa
ENSG00000055044	NOP58	87	93.220	ENSTGUG00000010124	NOP58	86	82.119	Taeniopygia_guttata
ENSG00000055044	NOP58	87	47.024	ENSTRUG00000015355	nop56	80	43.622	Takifugu_rubripes
ENSG00000055044	NOP58	91	84.118	ENSTRUG00000005053	nop58	94	81.560	Takifugu_rubripes
ENSG00000055044	NOP58	87	47.337	ENSTNIG00000010675	nop56	72	43.171	Tetraodon_nigroviridis
ENSG00000055044	NOP58	92	99.419	ENSTBEG00000006153	NOP58	100	85.991	Tupaia_belangeri
ENSG00000055044	NOP58	68	49.242	ENSTBEG00000011249	NOP56	68	40.821	Tupaia_belangeri
ENSG00000055044	NOP58	87	49.102	ENSTTRG00000003451	NOP56	91	38.949	Tursiops_truncatus
ENSG00000055044	NOP58	100	96.975	ENSTTRG00000006018	NOP58	100	96.975	Tursiops_truncatus
ENSG00000055044	NOP58	87	49.102	ENSUAMG00000006010	NOP56	62	44.444	Ursus_americanus
ENSG00000055044	NOP58	98	96.176	ENSUAMG00000025100	NOP58	97	100.000	Ursus_americanus
ENSG00000055044	NOP58	100	96.111	ENSUMAG00000021875	NOP58	100	96.111	Ursus_maritimus
ENSG00000055044	NOP58	87	49.102	ENSUMAG00000002172	NOP56	62	45.745	Ursus_maritimus
ENSG00000055044	NOP58	94	92.188	ENSVPAG00000006715	NOP58	100	84.528	Vicugna_pacos
ENSG00000055044	NOP58	87	49.102	ENSVVUG00000025634	NOP56	68	44.444	Vulpes_vulpes
ENSG00000055044	NOP58	100	95.933	ENSVVUG00000018258	NOP58	100	95.933	Vulpes_vulpes
ENSG00000055044	NOP58	91	87.647	ENSXETG00000022073	nop58	99	74.812	Xenopus_tropicalis
ENSG00000055044	NOP58	83	45.912	ENSXETG00000014962	nop56	95	40.049	Xenopus_tropicalis
ENSG00000055044	NOP58	87	44.311	ENSXCOG00000009216	nop56	86	41.837	Xiphophorus_couchianus
ENSG00000055044	NOP58	91	82.456	ENSXCOG00000020520	nop58	94	81.087	Xiphophorus_couchianus
ENSG00000055044	NOP58	87	44.311	ENSXMAG00000001317	nop56	76	42.298	Xiphophorus_maculatus
ENSG00000055044	NOP58	91	82.456	ENSXMAG00000013666	nop58	93	81.087	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001094	TFIID-class transcription factor complex binding	17636026.	IPI	Function
GO:0001650	fibrillar center	-	IDA	Component
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	17636026.21522132.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	16687569.	IDA	Component
GO:0005730	nucleolus	10925205.	TAS	Component
GO:0005732	small nucleolar ribonucleoprotein complex	17636026.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006364	rRNA processing	10925205.	TAS	Process
GO:0015030	Cajal body	16687569.	IDA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0030515	snoRNA binding	21873635.	IBA	Function
GO:0030515	snoRNA binding	17636026.	IDA	Function
GO:0031428	box C/D snoRNP complex	21873635.	IBA	Component
GO:0031428	box C/D snoRNP complex	17636026.	NAS	Component
GO:0032040	small-subunit processome	21873635.	IBA	Component
GO:0048254	snoRNA localization	17636026.	IMP	Process
GO:0051117	ATPase binding	17636026.	IPI	Function
GO:0070761	pre-snoRNP complex	17636026.	IDA	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr2	202287678	Missense_Mutation	NA	L151F	0.25
BLCA	chr2	202287678	Missense_Mutation	NA	L151F	0.3
BLCA	chr2	202295677	Missense_Mutation	novel	S304F	0.14
BLCA	chr2	202295722	Frame_Shift_Del	novel	*G320Qfs6**	0.47
BLCA	chr2	202282446	Missense_Mutation	novel	D91N	0.16
BLCA	chr2	202300257	Missense_Mutation	NA	S431C	0.1
BRCA	chr2	202275134	Missense_Mutation	NA	Q23E	0.19	Nop
BRCA	chr2	202284395	Missense_Mutation	NA	M116I	0.27
BRCA	chr2	202291333	Intron	novel		0.14
BRCA	chr2	202297494	Missense_Mutation	NA	R396T	0.31
BRCA	chr2	202292829	Missense_Mutation	novel	R278L	0.08
BRCA	chr2	202297405	Silent	NA	T366T	0.26
BRCA	chr2	202303540	3'UTR	novel		0.46
BRCA	chr2	202300285	Frame_Shift_Ins	novel	*R443Tfs8**	0.07
CESC	chr2	202282403	Silent	NA	L76L	0.29
CESC	chr2	202295685	Missense_Mutation	NA	N307H	0.57
CESC	chr2	202284353	Silent	NA	L102L	0.3
CESC	chr2	202290450	Silent	NA	Q209Q	0.23
CESC	chr2	202287687	Silent	rs771516762	S154S	0.41
CESC	chr2	202303536	3'UTR	novel		0.48
CESC	chr2	202291410	Intron	rs183313920		0.41
CESC	chr2	202291175	Nonsense_Mutation	NA	E229*	0.18
COAD	chr2	202297386	Missense_Mutation	NA	R360Q	0.11
COAD	chr2	202292792	Nonsense_Mutation	NA	E266*	0.47
COAD	chr2	202297407	Missense_Mutation	NA	V367G	0.34
COAD	chr2	202265957	Nonsense_Mutation	novel	E6*	0.33	Nop
COAD	chr2	202303470	3'UTR	novel		0.31
COAD	chr2	202265957	Nonsense_Mutation	novel	E6*	0.43	Nop
COAD	chr2	202303403	Silent	novel	K519K	0.26
COAD	chr2	202290386	Missense_Mutation	NA	G188D	0.34
COAD	chr2	202284406	Missense_Mutation	rs755969953	R120H	0.09
COAD	chr2	202303049	Missense_Mutation	NA	A511T	0.1
COAD	chr2	202265933	5'UTR	novel		0.6
ESCA	chr2	202287671	Missense_Mutation	novel	Y149C	0.36
ESCA	chr2	202284366	Missense_Mutation	novel	I107F	0.27
GBM	chr2	202284405	Missense_Mutation	rs750188563	R120C	0.32
GBM	chr2	202284585	Intron	novel		0.29
GBM	chr2	202295768	Silent	novel	D334D	0.08
HNSC	chr2	202290387	Silent	novel	G188G	0.13
HNSC	chr2	202292828	Nonsense_Mutation	rs747894497	R278*	0.07
HNSC	chr2	202303405	Missense_Mutation	novel	K520R	0.15
KIRC	chr2	202303577	3'UTR	novel		0.45
KIRP	chr2	202291367	Intron	novel		0.4
KIRP	chr2	202300281	Missense_Mutation	novel	C439S	0.32
KIRP	chr2	202290423	Silent	NA	D200D	0.39
LAML	chr2	202297510	Silent	novel	R401R	0.04
LGG	chr2	202297886	Frame_Shift_Del	rs768783326	*E417Kfs3**	0.1
LGG	chr2	202300325	Missense_Mutation	novel	I454V	0.08
LIHC	chr2	202303503	3'UTR	novel		0.63
LUAD	chr2	202291205	Missense_Mutation	novel	E239K	0.21
LUAD	chr2	202284473	Missense_Mutation	novel	L142F	0.21
LUAD	chr2	202287668	Frame_Shift_Ins	novel	*R150Ifs3**	0.07
LUSC	chr2	202276475	Intron	novel		0.13
LUSC	chr2	202275173	Missense_Mutation	novel	E36K	0.35	Nop
LUSC	chr2	202302926	Missense_Mutation	NA	E470K	0.5
LUSC	chr2	202276461	Intron	novel		0.11
LUSC	chr2	202297378	Splice_Site	novel	X358_splice	0.09
LUSC	chr2	202282394	Missense_Mutation	novel	K73N	0.24
LUSC	chr2	202297390	Missense_Mutation	novel	M361I	0.27
LUSC	chr2	202276493	Intron	rs756190041		0.1
OV	chr2	202276435	Intron	novel		0.29
PCPG	chr2	202291198	Silent	novel	A236A	0.46
PRAD	chr2	202295712	Missense_Mutation	rs150533873	V316I	0.43
READ	chr2	202282375	Missense_Mutation	novel	K67T	0.26
READ	chr2	202284387	Nonsense_Mutation	NA	E114*	0.23
READ	chr2	202291345	Intron	novel		0.27
SKCM	chr2	202293087	Intron	novel		0.29
SKCM	chr2	202284368	Silent	NA	I107I	0.41
SKCM	chr2	202284465	Missense_Mutation	novel	L140F	0.39
SKCM	chr2	202293063	Intron	novel		0.16
SKCM	chr2	202293065	Intron	novel		0.19
SKCM	chr2	202284500	Intron	novel		0.16
SKCM	chr2	202284413	Silent	novel	Q122Q	0.39
SKCM	chr2	202295758	Missense_Mutation	NA	S331F	0.58
SKCM	chr2	202284405	Missense_Mutation	rs750188563	R120C	0.21
SKCM	chr2	202277978	Nonsense_Mutation	NA	Q51*	0.34	Nop
SKCM	chr2	202295800	Missense_Mutation	novel	S345L	0.3
SKCM	chr2	202300279	Silent	NA	T438T	0.25
SKCM	chr2	202265814	5'UTR	novel		0.58
SKCM	chr2	202292890	Silent	NA	L298L	0.24
STAD	chr2	202292798	Nonsense_Mutation	rs763440974	R268*	0.24
STAD	chr2	202291350	Intron	novel		0.12
STAD	chr2	202291391	Intron	novel		0.38
STAD	chr2	202275112	Splice_Site	novel	X16_splice	0.23
STAD	chr2	202275153	Missense_Mutation	novel	W29L	0.08	Nop
STAD	chr2	202295683	Missense_Mutation	NA	L306S	0.07
STAD	chr2	202303410	Frame_Shift_Del	NA	*K524Rfs22**	0.27
STAD	chr2	202303410	Frame_Shift_Del	NA	*K524Rfs22**	0.31
STAD	chr2	202303410	Frame_Shift_Del	NA	*K524Rfs22**	0.25
STAD	chr2	202303410	Frame_Shift_Del	NA	*K524Rfs22**	0.32
THCA	chr2	202300349	Frame_Shift_Ins	novel	*A462Vfs8**	0.12
UCEC	chr2	202287671	Missense_Mutation	NA	Y149S	0.2
UCEC	chr2	202300293	Missense_Mutation	rs541358227	R443H	0.45
UCEC	chr2	202292854	Silent	novel	V286V	0.46
UCEC	chr2	202276502	Intron	novel		0.44
UCEC	chr2	202265965	Silent	novel	S8S	0.39
UCEC	chr2	202292828	Nonsense_Mutation	rs747894497	R278*	0.05
UCEC	chr2	202276498	Intron	novel		0.43
UCEC	chr2	202295692	Missense_Mutation	NA	A309V	0.33
UCEC	chr2	202290451	Nonsense_Mutation	novel	K210*	0.28
UCEC	chr2	202276433	Intron	rs371977864		0.45
UCEC	chr2	202293072	Intron	novel		0.13
UCEC	chr2	202303018	Silent	novel	P500P	0.4
UCEC	chr2	202276485	Intron	novel		0.47
UCEC	chr2	202284601	Intron	novel		0.33
UCEC	chr2	202293108	Intron	novel		0.44
UCEC	chr2	202295791	Missense_Mutation	novel	Y342C	0.2
UCEC	chr2	202303541	3'UTR	novel		0.45
UCEC	chr2	202303049	Missense_Mutation	NA	A511T	0.4
UCEC	chr2	202303649	3'UTR	novel		0.38
UCEC	chr2	202275130	Silent	novel	K21K	0.35
UCEC	chr2	202303410	Frame_Shift_Del	NA	*K524Rfs22**	0.31
UCEC	chr2	202265931	5'UTR	rs371185656		0.33
UCEC	chr2	202292799	Missense_Mutation	novel	R268Q	0.16
UCEC	chr2	202303427	Silent	rs142267123	N527N	0.32
UCEC	chr2	202303410	Frame_Shift_Del	NA	*K524Rfs22**	0.46
UCEC	chr2	202284631	Intron	novel		0.33
UCEC	chr2	202287718	Missense_Mutation	novel	A165T	0.32
UCEC	chr2	202292828	Nonsense_Mutation	rs747894497	R278*	0.39
UCEC	chr2	202303054	Silent	novel	I512I	0.31
UCEC	chr2	202275127	Missense_Mutation	novel	K20N	0.42	Nop
UCEC	chr2	202292788	Silent	novel	I264I	0.3
UCEC	chr2	202303574	3'UTR	novel		0.7
UCEC	chr2	202303642	3'UTR	novel		0.39
UCEC	chr2	202300292	Missense_Mutation	rs759580885	R443C	0.18
UCEC	chr2	202303642	3'UTR	novel		0.11
UCEC	chr2	202303609	3'UTR	novel		0.07
UCEC	chr2	202265822	5'UTR	novel		0.08
UCEC	chr2	202265871	5'UTR	novel		0.6
UCEC	chr2	202282461	Missense_Mutation	NA	G96W	0.1
UCEC	chr2	202303410	Frame_Shift_Del	NA	*K524Rfs22**	0.2
UCEC	chr2	202284586	Intron	novel		0.48
UCEC	chr2	202303410	Frame_Shift_Del	NA	*K524Rfs22**	0.47
UCEC	chr2	202303483	3'UTR	novel		0.47
UCEC	chr2	202303618	3'UTR	novel		0.29
UCEC	chr2	202291187	Nonsense_Mutation	novel	E233*	0.05
UCEC	chr2	202292783	Nonsense_Mutation	NA	E263*	0.36
UCEC	chr2	202295696	Silent	NA	K310K	0.28
UCEC	chr2	202303040	Missense_Mutation	rs34523815	T508A	0.3
UCEC	chr2	202284358	Missense_Mutation	novel	L104P	0.22
UCEC	chr2	202303646	3'UTR	novel		0.43
UCEC	chr2	202290413	Missense_Mutation	novel	I197N	0.28
UCEC	chr2	202297418	Missense_Mutation	NA	R371C	0.32
UCS	chr2	202303465	3'UTR	novel		0.33

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
PAAD	AMP	0.0707	0.1091
PAAD	DEL	0.0272	0.2014

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00011	Kaplan-Meier Survival Analysis
STAD	0.048	Kaplan-Meier Survival Analysis
MESO	0.038	Kaplan-Meier Survival Analysis
ACC	0.0001	Kaplan-Meier Survival Analysis
UCS	0.05	Kaplan-Meier Survival Analysis
HNSC	0.021	Kaplan-Meier Survival Analysis
PRAD	0.024	Kaplan-Meier Survival Analysis
BRCA	0.038	Kaplan-Meier Survival Analysis
ESCA	0.016	Kaplan-Meier Survival Analysis
KIRP	0.00031	Kaplan-Meier Survival Analysis
PAAD	0.016	Kaplan-Meier Survival Analysis
UCEC	0.006	Kaplan-Meier Survival Analysis
LIHC	0.0001	Kaplan-Meier Survival Analysis
LUAD	0.03	Kaplan-Meier Survival Analysis
UVM	0.013	Kaplan-Meier Survival Analysis
OV	0.0021	Kaplan-Meier Survival Analysis