EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000059691 (Gene tree)
Gene ID: 5188
Gene Symbol: GATB
Alias: PET112L|PET112
Full Name: glutamyl-tRNA amidotransferase subunit B
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 90,972 bases
Position: chr4:151,670,052-151,761,023
Accession: 8849
RBP type: canonical RBP
Summary: (Glutamyl-TRNA Amidotransferase Subunit B) is a Protein Coding gene. Among its related pathways are Metabolism and tRNA Aminoacylation. Gene Ontology (GO) annotations related to this gene include ligase activity and translation factor activity, RNA binding.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000426859	GatB_Yqey	PF02637.18	2.5e-45	1	1
ENSP00000263985	GatB_Yqey	PF02637.18	2.8e-45	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000513504	GATB-210	582	-	-	- (aa)	-	-
ENST00000263985	GATB-201	2385	XM_005263063	ENSP00000263985	557 (aa)	-	O75879
ENST00000505211	GATB-203	697	-	-	- (aa)	-	-
ENST00000510720	GATB-207	874	-	ENSP00000425294	132 (aa)	-	H0Y9W6
ENST00000503160	GATB-202	1860	-	ENSP00000421005	136 (aa)	-	H0Y8G7
ENST00000507592	GATB-204	749	-	-	- (aa)	-	-
ENST00000508611	GATB-205	605	-	ENSP00000421105	115 (aa)	-	D6RGY4
ENST00000511538	GATB-208	1345	-	ENSP00000421240	146 (aa)	-	B4E0P2
ENST00000510396	GATB-206	3745	-	-	- (aa)	-	-
ENST00000515884	GATB-214	779	-	ENSP00000423999	141 (aa)	-	H0Y9F2
ENST00000515812	GATB-213	1893	-	ENSP00000426859	516 (aa)	-	D6REA0
ENST00000515564	GATB-212	6552	-	-	- (aa)	-	-
ENST00000512306	GATB-209	1519	-	ENSP00000420831	357 (aa)	-	D6RDU9
ENST00000515490	GATB-211	733	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000059691's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00970	Aminoacyl-tRNA biosynthesis	KEGG
hsa01100	Metabolic pathways	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000059691	Triglycerides	8.5180000E-006	-
ENSG00000059691	Platelet Function Tests	5.8000000E-006	-
ENSG00000059691	Trans Fatty Acids	1E-6	25646338
ENSG00000059691	Trans Fatty Acids	2E-6	25646338

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000059691	rs6840360	4	151682879	A	Intelligence (MTAG)	29326435	[0.015-0.026] unit decrease	0.020500738	EFO_0004337
ENSG00000059691	rs6535809	4	151671781	A	Cognitive performance	30038396	[0.014-0.025] unit increase	0.0196	EFO_0008354
ENSG00000059691	rs6823423	4	151683571	T	Educational attainment (MTAG)	30038396	[0.0052-0.0102] unit increase	0.0077	EFO_0004784
ENSG00000059691	rs6535809	4	151671781	A	Cognitive performance (MTAG)	30038396	[0.013-0.022] unit increase	0.0179	EFO_0008354
ENSG00000059691	rs12647420	4	151686039	?	General cognitive ability	29844566	z-score decrease	5.258	EFO_0004337
ENSG00000059691	rs6535809	4	151671781	A	Intelligence	29942086	z-score increase	7.186	EFO_0004337
ENSG00000059691	rs4696108	4	151685823	T	Intelligence	29942086	z-score increase	6.399	EFO_0004337
ENSG00000059691	rs1355413	4	151712515	?	Educational attainment (years of education)	30595370			EFO_0004784

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000059691's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000059691	GATB	80	77.817	ENSAPOG00000022676	gatb	92	67.396	Acanthochromis_polyacanthus
ENSG00000059691	GATB	99	86.941	ENSAMEG00000018434	GATB	99	86.941	Ailuropoda_melanoleuca
ENSG00000059691	GATB	78	65.675	ENSACIG00000015827	gatb	100	65.675	Amphilophus_citrinellus
ENSG00000059691	GATB	78	79.137	ENSAOCG00000009635	gatb	95	68.008	Amphiprion_ocellaris
ENSG00000059691	GATB	89	65.524	ENSAPEG00000023666	gatb	93	65.524	Amphiprion_percula
ENSG00000059691	GATB	93	65.511	ENSATEG00000011821	gatb	97	65.708	Anabas_testudineus
ENSG00000059691	GATB	89	75.101	ENSAPLG00000003933	GATB	99	75.101	Anas_platyrhynchos
ENSG00000059691	GATB	95	74.269	ENSACAG00000002772	GATB	100	69.107	Anolis_carolinensis
ENSG00000059691	GATB	98	95.105	ENSANAG00000020953	GATB	100	92.280	Aotus_nancymaae
ENSG00000059691	GATB	82	65.646	ENSACLG00000026091	gatb	91	66.444	Astatotilapia_calliptera
ENSG00000059691	GATB	78	76.534	ENSAMXG00000021662	gatb	89	62.725	Astyanax_mexicanus
ENSG00000059691	GATB	98	86.713	ENSBTAG00000013914	GATB	99	85.612	Bos_taurus
ENSG00000059691	GATB	98	96.503	ENSCJAG00000002147	GATB	99	92.986	Callithrix_jacchus
ENSG00000059691	GATB	99	85.791	ENSCAFG00000008088	GATB	99	85.791	Canis_familiaris
ENSG00000059691	GATB	99	85.432	ENSCAFG00020026686	GATB	98	86.837	Canis_lupus_dingo
ENSG00000059691	GATB	99	85.432	ENSCHIG00000020111	GATB	99	85.432	Capra_hircus
ENSG00000059691	GATB	99	89.928	ENSTSYG00000009976	GATB	99	89.928	Carlito_syrichta
ENSG00000059691	GATB	99	77.148	ENSCAPG00000010977	GATB	99	77.148	Cavia_aperea
ENSG00000059691	GATB	99	82.278	ENSCPOG00000005023	GATB	99	82.278	Cavia_porcellus
ENSG00000059691	GATB	97	93.431	ENSCCAG00000021445	GATB	95	92.781	Cebus_capucinus
ENSG00000059691	GATB	99	95.863	ENSCATG00000034281	GATB	99	95.863	Cercocebus_atys
ENSG00000059691	GATB	95	89.922	ENSCLAG00000005772	GATB	99	86.170	Chinchilla_lanigera
ENSG00000059691	GATB	99	94.784	ENSCSAG00000003318	GATB	99	94.784	Chlorocebus_sabaeus
ENSG00000059691	GATB	98	86.014	ENSCHOG00000008476	GATB	99	84.532	Choloepus_hoffmanni
ENSG00000059691	GATB	99	70.179	ENSCPBG00000025824	GATB	99	70.179	Chrysemys_picta_bellii
ENSG00000059691	GATB	99	95.324	ENSCANG00000029227	GATB	99	95.324	Colobus_angolensis_palliatus
ENSG00000059691	GATB	100	84.381	ENSCGRG00001024051	GATB	99	86.170	Cricetulus_griseus_chok1gshd
ENSG00000059691	GATB	100	84.381	ENSCGRG00000012974	GATB	99	86.170	Cricetulus_griseus_crigri
ENSG00000059691	GATB	80	77.113	ENSCSEG00000004009	gatb	100	62.929	Cynoglossus_semilaevis
ENSG00000059691	GATB	89	67.404	ENSCVAG00000017180	gatb	99	67.404	Cyprinodon_variegatus
ENSG00000059691	GATB	78	79.061	ENSDARG00000037309	gatb	90	66.061	Danio_rerio
ENSG00000059691	GATB	99	84.229	ENSDNOG00000012683	GATB	100	84.229	Dasypus_novemcinctus
ENSG00000059691	GATB	99	83.935	ENSDORG00000010241	Gatb	99	83.935	Dipodomys_ordii
ENSG00000059691	GATB	78	59.353	FBgn0039153	GatB	95	44.980	Drosophila_melanogaster
ENSG00000059691	GATB	81	88.785	ENSETEG00000002356	GATB	99	63.129	Echinops_telfairi
ENSG00000059691	GATB	81	42.991	ENSEBUG00000005611	-	95	42.000	Eptatretus_burgeri
ENSG00000059691	GATB	99	88.669	ENSEASG00005015868	GATB	99	88.669	Equus_asinus_asinus
ENSG00000059691	GATB	99	86.691	ENSECAG00000003539	GATB	99	86.691	Equus_caballus
ENSG00000059691	GATB	98	79.720	ENSEEUG00000002311	GATB	85	74.615	Erinaceus_europaeus
ENSG00000059691	GATB	80	75.704	ENSELUG00000013584	gatb	96	64.980	Esox_lucius
ENSG00000059691	GATB	99	86.151	ENSFCAG00000003207	GATB	99	86.151	Felis_catus
ENSG00000059691	GATB	80	72.707	ENSFALG00000002209	GATB	99	72.707	Ficedula_albicollis
ENSG00000059691	GATB	98	86.713	ENSFDAG00000006426	GATB	99	86.809	Fukomys_damarensis
ENSG00000059691	GATB	78	78.058	ENSFHEG00000008643	GATB	91	66.801	Fundulus_heteroclitus
ENSG00000059691	GATB	88	65.854	ENSGMOG00000001575	gatb	100	65.854	Gadus_morhua
ENSG00000059691	GATB	98	70.128	ENSGALG00000010097	GATB	99	70.128	Gallus_gallus
ENSG00000059691	GATB	92	65.039	ENSGAFG00000014422	gatb	94	64.329	Gambusia_affinis
ENSG00000059691	GATB	88	66.327	ENSGACG00000017143	gatb	99	66.327	Gasterosteus_aculeatus
ENSG00000059691	GATB	99	70.088	ENSGAGG00000007826	GATB	99	70.088	Gopherus_agassizii
ENSG00000059691	GATB	100	99.641	ENSGGOG00000011099	GATB	100	99.641	Gorilla_gorilla
ENSG00000059691	GATB	80	77.544	ENSHBUG00000009656	gatb	90	68.081	Haplochromis_burtoni
ENSG00000059691	GATB	96	88.235	ENSHGLG00000001316	GATB	100	86.229	Heterocephalus_glaber_female
ENSG00000059691	GATB	96	88.235	ENSHGLG00100004289	GATB	99	86.170	Heterocephalus_glaber_male
ENSG00000059691	GATB	78	76.534	ENSHCOG00000006270	gatb	90	65.191	Hippocampus_comes
ENSG00000059691	GATB	78	78.700	ENSIPUG00000013560	gatb	90	65.524	Ictalurus_punctatus
ENSG00000059691	GATB	100	85.099	ENSSTOG00000005689	GATB	100	85.099	Ictidomys_tridecemlineatus
ENSG00000059691	GATB	99	82.914	ENSJJAG00000016979	Gatb	99	84.894	Jaculus_jaculus
ENSG00000059691	GATB	80	78.169	ENSKMAG00000004727	gatb	92	67.793	Kryptolebias_marmoratus
ENSG00000059691	GATB	89	72.152	ENSLBEG00000019511	gatb	95	64.486	Labrus_bergylta
ENSG00000059691	GATB	89	63.968	ENSLACG00000004352	GATB	97	64.372	Latimeria_chalumnae
ENSG00000059691	GATB	69	81.915	ENSLOCG00000008564	gatb	89	61.044	Lepisosteus_oculatus
ENSG00000059691	GATB	99	85.791	ENSLAFG00000022607	GATB	99	85.791	Loxodonta_africana
ENSG00000059691	GATB	99	95.504	ENSMMUG00000011048	GATB	99	95.504	Macaca_mulatta
ENSG00000059691	GATB	99	95.324	ENSMNEG00000040147	GATB	99	95.324	Macaca_nemestrina
ENSG00000059691	GATB	99	95.144	ENSMLEG00000042135	GATB	99	95.144	Mandrillus_leucophaeus
ENSG00000059691	GATB	84	73.913	ENSMAMG00000013256	gatb	92	66.600	Mastacembelus_armatus
ENSG00000059691	GATB	90	67.659	ENSMZEG00005008495	gatb	92	67.659	Maylandia_zebra
ENSG00000059691	GATB	89	75.911	ENSMGAG00000004276	GATB	98	75.911	Meleagris_gallopavo
ENSG00000059691	GATB	100	84.381	ENSMAUG00000019099	Gatb	99	85.532	Mesocricetus_auratus
ENSG00000059691	GATB	99	88.669	ENSMICG00000004311	GATB	99	88.669	Microcebus_murinus
ENSG00000059691	GATB	100	84.919	ENSMOCG00000017566	Gatb	99	86.596	Microtus_ochrogaster
ENSG00000059691	GATB	95	60.327	ENSMMOG00000005376	gatb	91	60.327	Mola_mola
ENSG00000059691	GATB	99	75.850	ENSMODG00000001031	GATB	99	75.850	Monodelphis_domestica
ENSG00000059691	GATB	80	76.761	ENSMALG00000003418	gatb	90	68.913	Monopterus_albus
ENSG00000059691	GATB	100	84.381	MGP_CAROLIEiJ_G0025120	Gatb	99	85.987	Mus_caroli
ENSG00000059691	GATB	100	85.458	ENSMUSG00000028085	Gatb	99	87.021	Mus_musculus
ENSG00000059691	GATB	100	84.919	MGP_PahariEiJ_G0026563	Gatb	99	85.957	Mus_pahari
ENSG00000059691	GATB	100	85.099	MGP_SPRETEiJ_G0026062	Gatb	100	85.099	Mus_spretus
ENSG00000059691	GATB	99	86.511	ENSMPUG00000007394	GATB	99	86.511	Mustela_putorius_furo
ENSG00000059691	GATB	99	86.871	ENSMLUG00000008194	GATB	99	86.871	Myotis_lucifugus
ENSG00000059691	GATB	99	86.691	ENSNGAG00000002152	Gatb	99	87.660	Nannospalax_galili
ENSG00000059691	GATB	78	65.831	ENSNBRG00000005947	gatb	100	65.831	Neolamprologus_brichardi
ENSG00000059691	GATB	100	96.409	ENSNLEG00000005836	GATB	100	96.409	Nomascus_leucogenys
ENSG00000059691	GATB	89	78.990	ENSMEUG00000001479	GATB	99	79.150	Notamacropus_eugenii
ENSG00000059691	GATB	100	84.436	ENSOPRG00000011496	GATB	99	84.436	Ochotona_princeps
ENSG00000059691	GATB	96	88.235	ENSODEG00000005429	GATB	99	86.383	Octodon_degus
ENSG00000059691	GATB	80	77.895	ENSONIG00000010059	gatb	92	67.460	Oreochromis_niloticus
ENSG00000059691	GATB	81	76.636	ENSOANG00000005282	GATB	99	78.161	Ornithorhynchus_anatinus
ENSG00000059691	GATB	99	84.353	ENSOCUG00000016875	GATB	99	84.353	Oryctolagus_cuniculus
ENSG00000059691	GATB	88	66.053	ENSORLG00000007740	gatb	99	65.517	Oryzias_latipes
ENSG00000059691	GATB	82	75.000	ENSORLG00020016385	gatb	91	66.800	Oryzias_latipes_hni
ENSG00000059691	GATB	89	66.466	ENSOMEG00000003089	gatb	91	66.466	Oryzias_melastigma
ENSG00000059691	GATB	99	85.971	ENSOGAG00000014181	GATB	99	85.971	Otolemur_garnettii
ENSG00000059691	GATB	98	86.014	ENSOARG00000004355	GATB	99	84.615	Ovis_aries
ENSG00000059691	GATB	100	99.820	ENSPPAG00000041690	GATB	100	99.820	Pan_paniscus
ENSG00000059691	GATB	99	85.791	ENSPPRG00000004993	GATB	99	85.791	Panthera_pardus
ENSG00000059691	GATB	99	86.331	ENSPTIG00000021433	GATB	99	86.331	Panthera_tigris_altaica
ENSG00000059691	GATB	98	99.301	ENSPTRG00000016513	GATB	100	95.520	Pan_troglodytes
ENSG00000059691	GATB	99	95.534	ENSPANG00000024036	GATB	99	95.534	Papio_anubis
ENSG00000059691	GATB	88	70.347	ENSPKIG00000017076	gatb	96	67.742	Paramormyrops_kingsleyae
ENSG00000059691	GATB	98	70.092	ENSPSIG00000017832	GATB	98	70.092	Pelodiscus_sinensis
ENSG00000059691	GATB	88	61.790	ENSPMGG00000016497	gatb	89	61.790	Periophthalmus_magnuspinnatus
ENSG00000059691	GATB	100	84.919	ENSPEMG00000011096	Gatb	99	86.170	Peromyscus_maniculatus_bairdii
ENSG00000059691	GATB	99	76.036	ENSPCIG00000015213	GATB	99	76.036	Phascolarctos_cinereus
ENSG00000059691	GATB	89	66.600	ENSPFOG00000009933	gatb	91	66.600	Poecilia_formosa
ENSG00000059691	GATB	89	67.203	ENSPLAG00000015569	gatb	94	64.990	Poecilia_latipinna
ENSG00000059691	GATB	89	66.197	ENSPMEG00000006100	gatb	94	64.386	Poecilia_mexicana
ENSG00000059691	GATB	89	66.197	ENSPREG00000000128	gatb	94	64.458	Poecilia_reticulata
ENSG00000059691	GATB	100	97.846	ENSPPYG00000015121	GATB	100	97.846	Pongo_abelii
ENSG00000059691	GATB	96	80.147	ENSPCAG00000005950	GATB	100	65.350	Procavia_capensis
ENSG00000059691	GATB	97	90.018	ENSPCOG00000021777	GATB	99	89.600	Propithecus_coquereli
ENSG00000059691	GATB	99	87.590	ENSPVAG00000006891	GATB	99	87.590	Pteropus_vampyrus
ENSG00000059691	GATB	90	67.659	ENSPNYG00000013884	gatb	92	67.659	Pundamilia_nyererei
ENSG00000059691	GATB	76	77.656	ENSPNAG00000020150	gatb	89	65.517	Pygocentrus_nattereri
ENSG00000059691	GATB	100	83.483	ENSRNOG00000037655	Gatb	100	83.483	Rattus_norvegicus
ENSG00000059691	GATB	99	95.340	ENSRBIG00000006453	GATB	99	95.340	Rhinopithecus_bieti
ENSG00000059691	GATB	99	95.324	ENSRROG00000041575	GATB	99	95.324	Rhinopithecus_roxellana
ENSG00000059691	GATB	78	36.713	YBL080C	-	85	31.211	Saccharomyces_cerevisiae
ENSG00000059691	GATB	99	92.266	ENSSBOG00000022495	GATB	99	92.266	Saimiri_boliviensis_boliviensis
ENSG00000059691	GATB	99	74.731	ENSSHAG00000011763	GATB	99	74.731	Sarcophilus_harrisii
ENSG00000059691	GATB	96	66.045	ENSSFOG00015015565	gatb	97	65.922	Scleropages_formosus
ENSG00000059691	GATB	82	75.601	ENSSMAG00000003609	gatb	73	65.524	Scophthalmus_maximus
ENSG00000059691	GATB	82	76.632	ENSSDUG00000019847	gatb	92	66.929	Seriola_dumerili
ENSG00000059691	GATB	89	67.879	ENSSLDG00000010253	gatb	95	67.879	Seriola_lalandi_dorsalis
ENSG00000059691	GATB	98	81.119	ENSSARG00000003212	GATB	76	71.642	Sorex_araneus
ENSG00000059691	GATB	97	68.663	ENSSPUG00000014453	GATB	96	74.239	Sphenodon_punctatus
ENSG00000059691	GATB	89	68.612	ENSSPAG00000014465	gatb	99	68.612	Stegastes_partitus
ENSG00000059691	GATB	99	84.532	ENSSSCG00000009015	GATB	99	85.550	Sus_scrofa
ENSG00000059691	GATB	89	75.304	ENSTGUG00000004986	GATB	99	75.304	Taeniopygia_guttata
ENSG00000059691	GATB	73	78.544	ENSTRUG00000015238	gatb	92	61.265	Takifugu_rubripes
ENSG00000059691	GATB	81	57.407	ENSTNIG00000003378	gatb	99	63.415	Tetraodon_nigroviridis
ENSG00000059691	GATB	81	87.037	ENSTBEG00000009804	GATB	88	63.761	Tupaia_belangeri
ENSG00000059691	GATB	99	84.892	ENSTTRG00000010679	GATB	99	84.892	Tursiops_truncatus
ENSG00000059691	GATB	99	87.770	ENSUAMG00000021441	GATB	99	87.770	Ursus_americanus
ENSG00000059691	GATB	99	87.410	ENSUMAG00000016157	GATB	99	87.410	Ursus_maritimus
ENSG00000059691	GATB	94	77.313	ENSVPAG00000010844	GATB	80	77.313	Vicugna_pacos
ENSG00000059691	GATB	99	86.151	ENSVVUG00000025083	GATB	99	86.151	Vulpes_vulpes
ENSG00000059691	GATB	87	70.842	ENSXETG00000034167	GATB	98	70.648	Xenopus_tropicalis
ENSG00000059691	GATB	96	61.296	ENSXMAG00000008071	gatb	90	78.344	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005524	ATP binding	-	IEA	Function
GO:0005739	mitochondrion	21873635.	IBA	Component
GO:0005739	mitochondrion	19805282.	IDA	Component
GO:0006412	translation	9878253.	TAS	Process
GO:0008135	translation factor activity, RNA binding	9878253.	TAS	Function
GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex	21873635.	IBA	Component
GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex	19805282.	IDA	Component
GO:0032543	mitochondrial translation	21873635.	IBA	Process
GO:0032543	mitochondrial translation	19805282.	IMP	Process
GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	21873635.	IBA	Function
GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity	19805282.	IDA	Function
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	21873635.	IBA	Process
GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation	19805282.	IDA	Process