EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000064932 (Gene tree)
Gene ID: 22904
Gene Symbol: SBNO2
Alias: FLJ00173|Stno|Sno|KIAA0963
Full Name: strawberry notch homolog 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 66,650 bases
Position: chr19:1,107,634-1,174,283
Accession: 29158
RBP type: canonical RBP
Summary: SBNO2 (Strawberry Notch Homolog 2) is a Protein Coding gene. An important paralog of this gene is SBNO1.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000400762	ResIII	PF04851.15	2.7e-05	1	1
ENSP00000468520	ResIII	PF04851.15	2.9e-05	1	1
ENSP00000354733	ResIII	PF04851.15	2.9e-05	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000361757	SBNO2-201	4923	XM_011527804	ENSP00000354733	1366 (aa)	XP_011526106	Q9Y2G9
ENST00000586109	SBNO2-203	465	-	-	- (aa)	-	-
ENST00000590446	SBNO2-208	587	-	-	- (aa)	-	-
ENST00000587024	SBNO2-204	4861	-	ENSP00000468520	1356 (aa)	-	K7ES28
ENST00000590998	SBNO2-209	562	-	ENSP00000468534	128 (aa)	-	K7ENA9
ENST00000587673	SBNO2-206	1209	-	-	- (aa)	-	-
ENST00000438103	SBNO2-202	4537	-	ENSP00000400762	1309 (aa)	-	Q9Y2G9
ENST00000587655	SBNO2-205	914	-	ENSP00000468302	111 (aa)	-	K7ERL2
ENST00000590176	SBNO2-207	561	-	ENSP00000466861	128 (aa)	-	K7ENA9
ENST00000592222	SBNO2-210	2403	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000064932's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000064932	Erythrocyte Indices	2.5570000E-005	-
ENSG00000064932	Cholesterol, LDL	1.0430000E-005	-
ENSG00000064932	Cholesterol	7.6470000E-006	-
ENSG00000064932	Inflammatory Bowel Diseases	5E-17	28067908
ENSG00000064932	Crohn Disease	8E-12	21102463
ENSG00000064932	Crohn Disease	7E-25	26192919
ENSG00000064932	Inflammatory Bowel Diseases	1E-18	26192919
ENSG00000064932	Crohn Disease	8E-22	23128233
ENSG00000064932	Crohn Disease	1E-20	28067908

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000064932	rs35971149	19	1164199	C	High light scatter reticulocyte count	27863252	[0.029-0.044] unit decrease	0.03683046	EFO_0007986
ENSG00000064932	rs35971149	19	1164199	C	High light scatter reticulocyte percentage of red cells	27863252	[0.03-0.046] unit decrease	0.03794556	EFO_0007986
ENSG00000064932	rs35971149	19	1164199	C	Reticulocyte count	27863252	[0.023-0.038] unit decrease	0.0305964	EFO_0007986
ENSG00000064932	rs740495	19	1124836	G	Crohn's disease	21102463	[1.10-1.21]	1.16	EFO_0000384
ENSG00000064932	rs2024092	19	1124032	A	Crohn's disease	26192919	[1.13-1.19]	1.159123	EFO_0000384
ENSG00000064932	rs2024092	19	1124032	A	Inflammatory bowel disease	26192919	[1.09-1.14]	1.1127257	EFO_0003767
ENSG00000064932	rs2024092	19	1124032	A	Crohn's disease	23128233	[1.112-1.201]	1.156	EFO_0000384
ENSG00000064932	rs4807629	19	1170298	A	Heel bone mineral density	28869591	[0.015-0.037] unit increase	0.0260852	EFO_0009270
ENSG00000064932	rs4807629	19	1170298	A	Heel bone mineral density	28869591	[0.025-0.04] unit increase	0.0323465	EFO_0009270
ENSG00000064932	rs4807629	19	1170298	A	Heel bone mineral density	28869591	[0.024-0.044] unit increase	0.0337472	EFO_0009270
ENSG00000064932	rs12462901	19	1166411	?	Tonsillectomy	28928442	[0.024-0.06] unit increase	0.0421	EFO_0007924
ENSG00000064932	rs55688536	19	1123177	?	White blood cell count	29403010	[0.024-0.05] unit decrease novel	0.03693	EFO_0004308
ENSG00000064932	rs35971149	19	1164199	C	Reticulocyte fraction of red cells	27863252	[0.025-0.041] unit decrease	0.03316492	EFO_0007986
ENSG00000064932	rs35971149	19	1164199	C	Immature fraction of reticulocytes	27863252	[0.025-0.04] unit decrease	0.03214381	EFO_0007986
ENSG00000064932	rs2024092	19	1124032	?	Crohn's disease	28067908			EFO_0000384
ENSG00000064932	rs2024092	19	1124032	?	Inflammatory bowel disease	28067908			EFO_0003767
ENSG00000064932	rs150434627	19	1166042	?	Heel bone mineral density	30048462	[0.035-0.05] unit increase	0.0427938	EFO_0009270
ENSG00000064932	rs11668064	19	1169067	?	Heel bone mineral density	30048462	[0.031-0.04] unit increase	0.0356519	EFO_0009270
ENSG00000064932	rs4807629	19	1170298	?	Heel bone mineral density	30048462	[0.031-0.04] unit increase	0.035301	EFO_0009270
ENSG00000064932	rs11668064	19	1169067	A	Heel bone mineral density	30598549	[0.03-0.038] unit increase	0.0343142	EFO_0009270
ENSG00000064932	rs2074919	19	1127982	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000064932	rs879983	19	1132638	?	White blood cell count	30595370			EFO_0004308
ENSG00000064932	rs57813069	19	1167158	?	Heel bone mineral density	30595370			EFO_0009270
ENSG00000064932	rs1433130	19	1172571	?	Red blood cell count	30595370			EFO_0004305
ENSG00000064932	rs7249065	19	1112944	G	Systemic lupus erythematosus	28714469	[1.16-1.45]	1.3	EFO_0002690
ENSG00000064932	rs117830785	19	1173894	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000064932's network

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000064932	SBNO2	87	69.384	ENSAPOG00000003185	si:ch73-63e15.2	87	67.892	Acanthochromis_polyacanthus
ENSG00000064932	SBNO2	88	68.547	ENSAOCG00000016581	si:ch73-63e15.2	95	68.902	Amphiprion_ocellaris
ENSG00000064932	SBNO2	88	68.803	ENSAPEG00000008862	si:ch73-63e15.2	76	68.664	Amphiprion_percula
ENSG00000064932	SBNO2	88	68.632	ENSATEG00000023838	si:ch73-63e15.2	94	70.466	Anabas_testudineus
ENSG00000064932	SBNO2	97	71.889	ENSAPLG00000007158	SBNO2	100	71.045	Anas_platyrhynchos
ENSG00000064932	SBNO2	100	92.167	ENSANAG00000026685	SBNO2	100	91.874	Aotus_nancymaae
ENSG00000064932	SBNO2	87	68.750	ENSACLG00000005090	si:ch73-63e15.2	77	64.776	Astatotilapia_calliptera
ENSG00000064932	SBNO2	88	69.157	ENSAMXG00000015881	si:ch73-63e15.2	84	68.696	Astyanax_mexicanus
ENSG00000064932	SBNO2	90	66.364	ENSAMXG00000018868	sbno2a	97	69.392	Astyanax_mexicanus
ENSG00000064932	SBNO2	98	86.708	ENSBTAG00000020780	SBNO2	100	86.084	Bos_taurus
ENSG00000064932	SBNO2	99	85.403	ENSCAFG00000019543	SBNO2	100	86.057	Canis_familiaris
ENSG00000064932	SBNO2	92	87.912	ENSCAFG00020017115	SBNO2	98	87.912	Canis_lupus_dingo
ENSG00000064932	SBNO2	97	87.696	ENSCHIG00000026127	SBNO2	100	85.188	Capra_hircus
ENSG00000064932	SBNO2	86	86.549	ENSCAPG00000005731	SBNO2	99	83.993	Cavia_aperea
ENSG00000064932	SBNO2	97	83.071	ENSCPOG00000007477	SBNO2	99	81.061	Cavia_porcellus
ENSG00000064932	SBNO2	100	92.055	ENSCCAG00000037518	SBNO2	100	91.979	Cebus_capucinus
ENSG00000064932	SBNO2	100	100.000	ENSCATG00000037046	SBNO2	100	98.316	Cercocebus_atys
ENSG00000064932	SBNO2	88	88.783	ENSCLAG00000010178	SBNO2	100	88.956	Chinchilla_lanigera
ENSG00000064932	SBNO2	100	99.219	ENSCSAG00000012317	SBNO2	100	98.097	Chlorocebus_sabaeus
ENSG00000064932	SBNO2	97	71.116	ENSCPBG00000008920	SBNO2	99	68.987	Chrysemys_picta_bellii
ENSG00000064932	SBNO2	100	100.000	ENSCANG00000036745	SBNO2	98	97.890	Colobus_angolensis_palliatus
ENSG00000064932	SBNO2	99	79.825	ENSCGRG00001023960	Sbno2	100	80.659	Cricetulus_griseus_chok1gshd
ENSG00000064932	SBNO2	97	83.542	ENSCGRG00000011984	Sbno2	100	81.845	Cricetulus_griseus_crigri
ENSG00000064932	SBNO2	87	66.346	ENSCSEG00000006856	si:ch73-63e15.2	90	70.194	Cynoglossus_semilaevis
ENSG00000064932	SBNO2	88	68.089	ENSCVAG00000005663	si:ch73-63e15.2	77	67.549	Cyprinodon_variegatus
ENSG00000064932	SBNO2	90	63.352	ENSDARG00000098801	sbno2a	90	62.758	Danio_rerio
ENSG00000064932	SBNO2	88	67.808	ENSDARG00000016188	SBNO2	82	67.324	Danio_rerio
ENSG00000064932	SBNO2	99	86.038	ENSDORG00000002916	Sbno2	100	85.223	Dipodomys_ordii
ENSG00000064932	SBNO2	99	85.627	ENSEASG00005021621	SBNO2	100	85.889	Equus_asinus_asinus
ENSG00000064932	SBNO2	99	85.627	ENSECAG00000011827	SBNO2	100	85.812	Equus_caballus
ENSG00000064932	SBNO2	87	69.660	ENSELUG00000020457	si:ch73-63e15.2	78	69.418	Esox_lucius
ENSG00000064932	SBNO2	90	74.771	ENSFALG00000013988	SBNO2	97	69.858	Ficedula_albicollis
ENSG00000064932	SBNO2	99	79.355	ENSFDAG00000015186	SBNO2	100	79.562	Fukomys_damarensis
ENSG00000064932	SBNO2	88	68.061	ENSFHEG00000022262	si:ch73-63e15.2	76	67.521	Fundulus_heteroclitus
ENSG00000064932	SBNO2	91	66.667	ENSGMOG00000007542	si:ch73-63e15.2	94	68.827	Gadus_morhua
ENSG00000064932	SBNO2	98	70.096	ENSGALG00000037522	SBNO2	92	68.881	Gallus_gallus
ENSG00000064932	SBNO2	89	67.489	ENSGAFG00000004860	si:ch73-63e15.2	91	67.551	Gambusia_affinis
ENSG00000064932	SBNO2	87	69.251	ENSGACG00000013190	si:ch73-63e15.2	94	69.686	Gasterosteus_aculeatus
ENSG00000064932	SBNO2	98	70.977	ENSGAGG00000008348	SBNO2	86	77.491	Gopherus_agassizii
ENSG00000064932	SBNO2	87	68.636	ENSHBUG00000010742	si:ch73-63e15.2	76	68.458	Haplochromis_burtoni
ENSG00000064932	SBNO2	99	85.631	ENSHGLG00000008739	SBNO2	100	85.432	Heterocephalus_glaber_female
ENSG00000064932	SBNO2	88	89.301	ENSHGLG00100005269	SBNO2	100	89.474	Heterocephalus_glaber_male
ENSG00000064932	SBNO2	89	66.810	ENSHCOG00000000884	si:ch73-63e15.2	86	67.324	Hippocampus_comes
ENSG00000064932	SBNO2	87	67.331	ENSIPUG00000019672	sbno2	93	69.958	Ictalurus_punctatus
ENSG00000064932	SBNO2	87	69.520	ENSIPUG00000000537	si:ch73-63e15.2	84	68.326	Ictalurus_punctatus
ENSG00000064932	SBNO2	99	85.965	ENSSTOG00000025832	SBNO2	100	85.892	Ictidomys_tridecemlineatus
ENSG00000064932	SBNO2	99	81.158	ENSJJAG00000017397	Sbno2	99	80.629	Jaculus_jaculus
ENSG00000064932	SBNO2	88	68.713	ENSKMAG00000005541	si:ch73-63e15.2	77	68.174	Kryptolebias_marmoratus
ENSG00000064932	SBNO2	88	67.811	ENSLBEG00000025016	si:ch73-63e15.2	95	70.386	Labrus_bergylta
ENSG00000064932	SBNO2	50	72.239	ENSLACG00000012598	SBNO2	96	75.430	Latimeria_chalumnae
ENSG00000064932	SBNO2	97	65.469	ENSLOCG00000004643	si:ch73-63e15.2	84	69.896	Lepisosteus_oculatus
ENSG00000064932	SBNO2	96	80.754	ENSLAFG00000008824	SBNO2	99	80.173	Loxodonta_africana
ENSG00000064932	SBNO2	100	100.000	ENSMFAG00000040030	SBNO2	100	93.928	Macaca_fascicularis
ENSG00000064932	SBNO2	100	100.000	ENSMMUG00000010886	SBNO2	100	98.170	Macaca_mulatta
ENSG00000064932	SBNO2	100	100.000	ENSMNEG00000039927	SBNO2	100	98.097	Macaca_nemestrina
ENSG00000064932	SBNO2	100	100.000	ENSMLEG00000038556	SBNO2	98	98.774	Mandrillus_leucophaeus
ENSG00000064932	SBNO2	88	68.349	ENSMAMG00000018758	si:ch73-63e15.2	75	68.065	Mastacembelus_armatus
ENSG00000064932	SBNO2	87	68.636	ENSMZEG00005010682	si:ch73-63e15.2	77	64.668	Maylandia_zebra
ENSG00000064932	SBNO2	99	72.637	ENSMGAG00000003801	SBNO2	99	71.721	Meleagris_gallopavo
ENSG00000064932	SBNO2	97	84.235	ENSMAUG00000008034	Sbno2	100	82.491	Mesocricetus_auratus
ENSG00000064932	SBNO2	99	88.668	ENSMICG00000013071	SBNO2	100	88.668	Microcebus_murinus
ENSG00000064932	SBNO2	97	84.289	ENSMOCG00000010504	Sbno2	100	81.918	Microtus_ochrogaster
ENSG00000064932	SBNO2	97	74.392	ENSMODG00000005382	SBNO2	99	71.589	Monodelphis_domestica
ENSG00000064932	SBNO2	73	64.780	ENSMALG00000021831	si:ch73-63e15.2	97	64.854	Monopterus_albus
ENSG00000064932	SBNO2	97	83.818	ENSMUSG00000035673	Sbno2	100	83.535	Mus_musculus
ENSG00000064932	SBNO2	97	84.041	MGP_PahariEiJ_G0030976	Sbno2	100	81.538	Mus_pahari
ENSG00000064932	SBNO2	97	84.041	MGP_SPRETEiJ_G0016381	Sbno2	100	81.465	Mus_spretus
ENSG00000064932	SBNO2	100	67.153	ENSMPUG00000008747	SBNO2	100	87.097	Mustela_putorius_furo
ENSG00000064932	SBNO2	97	82.075	ENSNGAG00000004308	Sbno2	100	79.912	Nannospalax_galili
ENSG00000064932	SBNO2	84	67.296	ENSNBRG00000022968	si:ch73-63e15.2	96	72.292	Neolamprologus_brichardi
ENSG00000064932	SBNO2	100	97.656	ENSNLEG00000001305	SBNO2	100	98.743	Nomascus_leucogenys
ENSG00000064932	SBNO2	76	75.556	ENSMEUG00000013511	-	78	75.132	Notamacropus_eugenii
ENSG00000064932	SBNO2	94	84.253	ENSOPRG00000017238	SBNO2	100	84.253	Ochotona_princeps
ENSG00000064932	SBNO2	97	83.752	ENSODEG00000011822	SBNO2	99	82.934	Octodon_degus
ENSG00000064932	SBNO2	87	68.810	ENSONIG00000002490	si:ch73-63e15.2	92	67.692	Oreochromis_niloticus
ENSG00000064932	SBNO2	88	67.468	ENSORLG00000000913	si:ch73-63e15.2	78	66.525	Oryzias_latipes
ENSG00000064932	SBNO2	88	67.466	ENSORLG00020010978	si:ch73-63e15.2	78	66.525	Oryzias_latipes_hni
ENSG00000064932	SBNO2	88	67.637	ENSORLG00015000202	si:ch73-63e15.2	78	66.695	Oryzias_latipes_hsok
ENSG00000064932	SBNO2	88	67.698	ENSOMEG00000000359	si:ch73-63e15.2	79	63.737	Oryzias_melastigma
ENSG00000064932	SBNO2	99	79.549	ENSOARG00000011130	SBNO2	100	79.158	Ovis_aries
ENSG00000064932	SBNO2	100	100.000	ENSPPAG00000032482	SBNO2	100	95.712	Pan_paniscus
ENSG00000064932	SBNO2	100	99.389	ENSPTRG00000010185	SBNO2	100	99.389	Pan_troglodytes
ENSG00000064932	SBNO2	100	99.219	ENSPANG00000009658	SBNO2	100	95.428	Papio_anubis
ENSG00000064932	SBNO2	80	70.370	ENSPKIG00000009707	-	83	70.686	Paramormyrops_kingsleyae
ENSG00000064932	SBNO2	88	67.728	ENSPKIG00000024201	si:ch73-63e15.2	83	68.439	Paramormyrops_kingsleyae
ENSG00000064932	SBNO2	74	79.898	ENSPSIG00000002852	SBNO2	100	79.695	Pelodiscus_sinensis
ENSG00000064932	SBNO2	88	67.040	ENSPMGG00000014375	si:ch73-63e15.2	87	67.403	Periophthalmus_magnuspinnatus
ENSG00000064932	SBNO2	97	82.011	ENSPEMG00000024122	Sbno2	100	79.722	Peromyscus_maniculatus_bairdii
ENSG00000064932	SBNO2	97	75.973	ENSPCIG00000011264	SBNO2	99	73.197	Phascolarctos_cinereus
ENSG00000064932	SBNO2	87	68.788	ENSPFOG00000004096	si:ch73-63e15.2	99	68.783	Poecilia_formosa
ENSG00000064932	SBNO2	88	67.836	ENSPLAG00000014653	si:ch73-63e15.2	77	67.723	Poecilia_latipinna
ENSG00000064932	SBNO2	88	67.665	ENSPMEG00000002129	si:ch73-63e15.2	88	71.016	Poecilia_mexicana
ENSG00000064932	SBNO2	87	68.229	ENSPREG00000006755	si:ch73-63e15.2	72	68.017	Poecilia_reticulata
ENSG00000064932	SBNO2	93	81.663	ENSPCAG00000012256	SBNO2	99	76.929	Procavia_capensis
ENSG00000064932	SBNO2	99	80.581	ENSPCOG00000015216	SBNO2	100	81.269	Propithecus_coquereli
ENSG00000064932	SBNO2	89	68.027	ENSPNYG00000019926	si:ch73-63e15.2	77	67.915	Pundamilia_nyererei
ENSG00000064932	SBNO2	88	69.031	ENSPNAG00000020260	si:ch73-63e15.2	83	69.013	Pygocentrus_nattereri
ENSG00000064932	SBNO2	89	65.950	ENSPNAG00000026609	sbno2a	86	69.344	Pygocentrus_nattereri
ENSG00000064932	SBNO2	97	84.591	ENSRNOG00000013987	Sbno2	98	84.355	Rattus_norvegicus
ENSG00000064932	SBNO2	100	92.188	ENSRBIG00000009740	SBNO2	94	88.445	Rhinopithecus_bieti
ENSG00000064932	SBNO2	100	99.219	ENSRROG00000044671	SBNO2	99	98.778	Rhinopithecus_roxellana
ENSG00000064932	SBNO2	100	92.899	ENSSBOG00000023562	SBNO2	100	92.899	Saimiri_boliviensis_boliviensis
ENSG00000064932	SBNO2	88	78.988	ENSSHAG00000010241	SBNO2	100	78.712	Sarcophilus_harrisii
ENSG00000064932	SBNO2	88	66.323	ENSSFOG00015005861	si:ch73-63e15.2	93	66.295	Scleropages_formosus
ENSG00000064932	SBNO2	88	67.750	ENSSMAG00000012489	si:ch73-63e15.2	74	67.637	Scophthalmus_maximus
ENSG00000064932	SBNO2	88	68.664	ENSSDUG00000003527	si:ch73-63e15.2	74	68.552	Seriola_dumerili
ENSG00000064932	SBNO2	88	68.579	ENSSLDG00000004623	si:ch73-63e15.2	74	68.466	Seriola_lalandi_dorsalis
ENSG00000064932	SBNO2	88	69.119	ENSSPAG00000017717	si:ch73-63e15.2	76	69.007	Stegastes_partitus
ENSG00000064932	SBNO2	97	87.011	ENSSSCG00000030042	SBNO2	98	86.459	Sus_scrofa
ENSG00000064932	SBNO2	85	68.901	ENSTRUG00000018193	si:ch73-63e15.2	86	69.161	Takifugu_rubripes
ENSG00000064932	SBNO2	87	89.118	ENSUAMG00000006568	SBNO2	99	87.871	Ursus_americanus
ENSG00000064932	SBNO2	99	82.820	ENSVVUG00000022823	SBNO2	90	88.141	Vulpes_vulpes
ENSG00000064932	SBNO2	79	70.327	ENSXETG00000021579	sbno2	97	69.419	Xenopus_tropicalis
ENSG00000064932	SBNO2	73	69.866	ENSXCOG00000009209	si:ch73-63e15.2	89	71.522	Xiphophorus_couchianus
ENSG00000064932	SBNO2	88	67.579	ENSXMAG00000012091	si:ch73-63e15.2	83	71.053	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0002281	macrophage activation involved in immune response	21873635.	IBA	Process
GO:0002281	macrophage activation involved in immune response	18025162.	IMP	Process
GO:0005575	cellular_component	-	ND	Component
GO:0005634	nucleus	21873635.	IBA	Component
GO:0030282	bone mineralization	-	IEA	Process
GO:0030316	osteoclast differentiation	21873635.	IBA	Process
GO:0045892	negative regulation of transcription, DNA-templated	21873635.	IBA	Process
GO:0045892	negative regulation of transcription, DNA-templated	18025162.	IMP	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0050727	regulation of inflammatory response	21873635.	IBA	Process
GO:0050727	regulation of inflammatory response	18025162.	IMP	Process
GO:0061430	bone trabecula morphogenesis	-	IEA	Process
GO:0071222	cellular response to lipopolysaccharide	-	ISS	Process
GO:0071348	cellular response to interleukin-11	-	ISS	Process
GO:0071354	cellular response to interleukin-6	21873635.	IBA	Process
GO:0071354	cellular response to interleukin-6	25903009.	IDA	Process
GO:0072675	osteoclast fusion	-	IEA	Process
GO:1990830	cellular response to leukemia inhibitory factor	-	ISS	Process