EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000065883 (Gene tree)
Gene ID: 8621
Gene Symbol: CDK13
Alias: CHED|CDC2L|KIAA1791|CDC2L5
Full Name: cyclin dependent kinase 13
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 149,935 bases
Position: chr7:39,949,646-40,099,580
Accession: 1733
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Alternatively spliced transcript variants have been described.[provided by RefSeq, Dec 2009]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000484589	CDK13-205	5166	-	ENSP00000494206	456 (aa)	-	A0A2R8YD28
ENST00000642592	CDK13-209	1047	-	ENSP00000494207	143 (aa)	-	A0A2R8YEB7
ENST00000643868	CDK13-213	1901	-	ENSP00000495083	279 (aa)	-	A0A2R8YFE7
ENST00000642213	CDK13-208	1053	-	-	- (aa)	-	-
ENST00000611390	CDK13-206	2222	-	ENSP00000484610	418 (aa)	-	A0A087X209
ENST00000478563	CDK13-204	904	-	-	- (aa)	-	-
ENST00000642626	CDK13-210	1150	-	ENSP00000493853	288 (aa)	-	A0A2R8YCQ1
ENST00000646437	CDK13-220	772	-	ENSP00000496618	257 (aa)	-	A0A2R8Y7Y0
ENST00000642660	CDK13-211	948	-	-	- (aa)	-	-
ENST00000643915	CDK13-214	3276	-	ENSP00000496187	915 (aa)	-	A0A2R8YF61
ENST00000340829	CDK13-202	5455	XM_017012751	ENSP00000340557	1452 (aa)	XP_016868240	Q14004
ENST00000643859	CDK13-212	3838	-	ENSP00000496440	1099 (aa)	-	A0A2R8Y7W5
ENST00000647453	CDK13-221	2998	-	-	- (aa)	-	-
ENST00000647518	CDK13-222	4190	-	-	- (aa)	-	-
ENST00000613626	CDK13-207	3099	-	ENSP00000480835	324 (aa)	-	Q9BVE2
ENST00000645826	CDK13-218	2250	-	-	- (aa)	-	-
ENST00000465643	CDK13-203	2394	-	-	- (aa)	-	-
ENST00000646039	CDK13-219	4466	-	ENSP00000494168	1308 (aa)	-	A0A2R8Y4Z0
ENST00000181839	CDK13-201	10135	XM_017012750	ENSP00000181839	1512 (aa)	XP_016868239	Q14004
ENST00000644561	CDK13-216	2576	-	-	- (aa)	-	-
ENST00000644221	CDK13-215	4511	-	-	- (aa)	-	-
ENST00000645470	CDK13-217	900	-	ENSP00000495036	239 (aa)	-	A0A2R8Y644

Gene Model

Click here to download ENSG00000065883's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000065883	Platelet Function Tests	4.3500000E-006	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000065883's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000065883	CDK13	100	99.163	ENSMUSG00000041297	Cdk13	100	98.276	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000307	cyclin-dependent protein kinase holoenzyme complex	21873635.	IBA	Component
GO:0000380	alternative mRNA splicing, via spliceosome	-	ISS	Process
GO:0000380	alternative mRNA splicing, via spliceosome	16721827.	TAS	Process
GO:0000790	nuclear chromatin	21873635.	IBA	Component
GO:0002945	cyclin K-CDK13 complex	22012619.	IPI	Component
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0004672	protein kinase activity	1731328.	TAS	Function
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	21873635.	IBA	Function
GO:0005515	protein binding	16721827.26748711.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005576	extracellular region	-	TAS	Component
GO:0005615	extracellular space	22664934.	HDA	Component
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005694	chromosome	21873635.	IBA	Component
GO:0005794	Golgi apparatus	-	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006368	transcription elongation from RNA polymerase II promoter	21873635.	IBA	Process
GO:0006468	protein phosphorylation	21873635.	IBA	Process
GO:0007088	regulation of mitotic nuclear division	1731328.	TAS	Process
GO:0007275	multicellular organism development	1731328.	TAS	Process
GO:0008024	cyclin/CDK positive transcription elongation factor complex	21873635.	IBA	Component
GO:0008134	transcription factor binding	21873635.	IBA	Function
GO:0008284	positive regulation of cell proliferation	1731328.	TAS	Process
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	21873635.	IBA	Function
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	20952539.	IDA	Function
GO:0016032	viral process	-	IEA	Process
GO:0016607	nuclear speck	16721827.	IDA	Component
GO:0019901	protein kinase binding	-	IEA	Function
GO:0019908	nuclear cyclin-dependent protein kinase holoenzyme complex	-	ISS	Component
GO:0030097	hemopoiesis	1731328.	IMP	Process
GO:0030332	cyclin binding	21873635.	IBA	Function
GO:0030332	cyclin binding	22012619.	IPI	Function
GO:0032968	positive regulation of transcription elongation from RNA polymerase II promoter	21873635.	IBA	Process
GO:0043312	neutrophil degranulation	-	TAS	Process
GO:0044212	transcription regulatory region DNA binding	21873635.	IBA	Function
GO:0045944	positive regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	21873635.	IBA	Process
GO:0070816	phosphorylation of RNA polymerase II C-terminal domain	20952539.	IDA	Process
GO:1904813	ficolin-1-rich granule lumen	-	TAS	Component
GO:2000737	negative regulation of stem cell differentiation	-	IEA	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
26886422	CDK13, a Kinase Involved in Pre-mRNA Splicing, Is a Component of the Perinucleolar Compartment.	PLoS One	2016 Feb 17	Even Y	doi: 10.1371/journal.pone.0149184
25216700	Protein deep sequencing applied to biobank samples from patients with pancreatic cancer.	J Cancer Res Clin Oncol	2015 Feb	Ansari D	doi: 10.1007/s00432-014-1817-x
22912832	Frequent amplification of CENPF, GMNN and CDK13 genes in hepatocellular carcinomas.	PLoS One	2012	Kim HE	doi: 10.1371/journal.pone.0043223
29996118	CDK13 RNA Over-Editing Mediated by ADAR1 Associates with Poor Prognosis of Hepatocellular Carcinoma Patients.	Cell Physiol Biochem	2018	Dong X	doi: 10.1159/000491656

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr7	40045856	Missense_Mutation	novel	E792K	0.41
BLCA	chr7	39988168	Frame_Shift_Del	novel	*K594Ifs21**	0.07
BLCA	chr7	39951640	Missense_Mutation	novel	Q333H	0.32
BLCA	chr7	40045929	Nonsense_Mutation	novel	S816*	0.39
BLCA	chr7	40062858	Nonsense_Mutation	novel	W878*	0.38
BLCA	chr7	39987799	Missense_Mutation	novel	A471E	0.09
BLCA	chr7	40095028	3'UTR	novel		0.12
BLCA	chr7	40063090	Nonsense_Mutation	novel	E924*	0.35
BLCA	chr7	40093008	Silent	rs778552078	S1153S	0.53
BLCA	chr7	40094433	Missense_Mutation	NA	S1331C	0.59
BLCA	chr7	40094198	Nonsense_Mutation	novel	R1253*	0.3
BLCA	chr7	40063041	Silent	novel	L907L	0.09
BLCA	chr7	39951638	Missense_Mutation	novel	Q333E	0.36
BLCA	chr7	39987800	Silent	rs779234602	A471A	0.31
BLCA	chr7	39988160	Frame_Shift_Del	novel	*K594Tfs20**	0.38
BLCA	chr7	39987705	Missense_Mutation	novel	P440S	0.45
BLCA	chr7	39987856	Missense_Mutation	novel	S490L	0.45
BLCA	chr7	40045929	Missense_Mutation	novel	S816L	0.27
BRCA	chr7	40094247	Missense_Mutation	novel	P1269L	0.29
BRCA	chr7	39988252	Missense_Mutation	NA	A622V	0.48
BRCA	chr7	40094258	Frame_Shift_Ins	novel	*E1273Vfs25**	0.08
BRCA	chr7	40078090	Missense_Mutation	NA	Y956H	0.34
BRCA	chr7	39999363	Missense_Mutation	NA	I682K	0.18
BRCA	chr7	40094157	Missense_Mutation	novel	D1239G	0.07
BRCA	chr7	39987629	Silent	rs202080779	P414P	0.22
BRCA	chr7	40092538	Intron	novel		0.67
BRCA	chr7	39988125	Missense_Mutation	NA	L580V	0.11
BRCA	chr7	40046004	Missense_Mutation	NA	S841F	0.3
BRCA	chr7	39999477	Missense_Mutation	novel	Y720C	0.48
BRCA	chr7	40094633	Nonsense_Mutation	novel	*E1398Vfs3**	0.07
BRCA	chr7	40093203	Silent	novel	L1218L	0.31
CESC	chr7	40078739	Missense_Mutation	NA	D973N	0.6
CESC	chr7	40094772	Missense_Mutation	NA	S1444F	0.18
CESC	chr7	40093034	Missense_Mutation	NA	S1162F	0.17
CESC	chr7	40092655	Intron	novel		0.59
CESC	chr7	40093039	Nonsense_Mutation	novel	Q1164*	0.36
CESC	chr7	40062911	Missense_Mutation	novel	D896Y	0.08
CESC	chr7	40045984	Silent	novel	L834L	0.29
CESC	chr7	40092753	Intron	novel		0.25
CESC	chr7	39999374	Missense_Mutation	NA	R686C	0.27
CESC	chr7	40002018	Missense_Mutation	novel	F780L	0.39
CESC	chr7	40078065	Missense_Mutation	novel	F947L	0.05
COAD	chr7	40094199	Missense_Mutation	rs150957134	R1253Q	0.09
COAD	chr7	40094966	Missense_Mutation	novel	G1509R	0.18
COAD	chr7	40045938	Missense_Mutation	NA	R819T	0.23
COAD	chr7	40094272	Silent	novel	Y1277Y	0.34
COAD	chr7	40094186	Missense_Mutation	NA	P1249A	0.23
COAD	chr7	40045942	Missense_Mutation	novel	Q820H	0.24
COAD	chr7	40062924	Missense_Mutation	NA	C900Y	0.39
COAD	chr7	40093178	Missense_Mutation	rs781777435	S1210L	0.64
COAD	chr7	40001877	Frame_Shift_Del	rs780713745	*V736Yfs32**	0.2
COAD	chr7	40063048	Frame_Shift_Del	NA	*K911Nfs13**	0.17
COAD	chr7	39951118	Frame_Shift_Del	NA	*A162Pfs174**	0.41
COAD	chr7	40001887	Missense_Mutation	novel	R737C	0.15
COAD	chr7	40088322	Missense_Mutation	novel	V1076M	0.13
COAD	chr7	39997626	Missense_Mutation	NA	K668N	0.18
COAD	chr7	40092830	Missense_Mutation	novel	I1094N	0.19
COAD	chr7	40092925	Missense_Mutation	novel	L1126I	0.07
COAD	chr7	40093167	Silent	NA	R1206R	0.16
COAD	chr7	40045975	Missense_Mutation	NA	K831N	0.46
COAD	chr7	40095000	3'UTR	novel		0.27
COAD	chr7	40062864	Missense_Mutation	rs761752355	R880H	0.25
DLBC	chr7	39951642	Missense_Mutation	novel	S334I	0.07
DLBC	chr7	39951004	Silent	novel	F121F	0.2
ESCA	chr7	39987991	Missense_Mutation	novel	D535G	0.41
ESCA	chr7	40088266	Missense_Mutation	novel	N1057T	0.09
ESCA	chr7	39951513	Missense_Mutation	novel	S291L	0.56
ESCA	chr7	40078820	Missense_Mutation	novel	D1000Y	0.08
ESCA	chr7	39987820	Missense_Mutation	novel	K478T	0.38
ESCA	chr7	39987788	Silent	rs137937704	A467A	0.11
GBM	chr7	40078040	Missense_Mutation	NA	P939L	0.28
GBM	chr7	39987605	Silent	novel	S406S	0.05
GBM	chr7	39999458	Missense_Mutation	NA	G714S	0.27
GBM	chr7	40092867	Missense_Mutation	novel	N1106K	0.07
GBM	chr7	39987700	Missense_Mutation	novel	I438S	0.42
GBM	chr7	40062902	Missense_Mutation	novel	P893A	0.04
GBM	chr7	39987669	Missense_Mutation	novel	L428V	0.08
GBM	chr7	40088133	Silent	novel	L1013L	0.11
GBM	chr7	40094438	Missense_Mutation	novel	S1333P	0.21
GBM	chr7	39987762	Missense_Mutation	novel	A459S	0.09
GBM	chr7	40094312	Silent	novel	L1291L	0.04
GBM	chr7	40094314	Silent	novel	L1291L	0.03
GBM	chr7	39997499	Missense_Mutation	novel	R626Q	0.22
GBM	chr7	40093008	Silent	rs778552078	S1153S	0.07
GBM	chr7	40094718	Missense_Mutation	NA	R1426I	0.24
GBM	chr7	40088132	Silent	novel	P1012P	0.13
GBM	chr7	40088184	Nonsense_Mutation	NA	Q1030*	0.23
HNSC	chr7	40094981	3'UTR	novel		0.34
HNSC	chr7	39987687	Missense_Mutation	rs371566821	R434C	0.45
HNSC	chr7	39999416	Missense_Mutation	rs760367885	R700C	0.27
HNSC	chr7	40094411	Nonsense_Mutation	novel	Q1324*	0.35
HNSC	chr7	39988254	Missense_Mutation	novel	D623N	0.24
HNSC	chr7	40001995	Missense_Mutation	novel	D773H	0.16
HNSC	chr7	40094677	Silent	rs752706166	L1412L	0.27
HNSC	chr7	39988228	Missense_Mutation	novel	P614L	0.19
HNSC	chr7	40088131	Missense_Mutation	novel	P1012L	0.2
KICH	chr7	40093220	Missense_Mutation	novel	P1224R	0.29
KIRC	chr7	40094826	Missense_Mutation	NA	Y1462C	0.51
KIRC	chr7	39951767	Missense_Mutation	NA	Y376H	0.33
KIRC	chr7	40094572	Missense_Mutation	NA	L1377F	0.34
KIRC	chr7	39988148	Frame_Shift_Ins	novel	*T588Nfs31**	0.11
KIRC	chr7	40046009	Missense_Mutation	NA	I843F	0.2
KIRP	chr7	40088208	Missense_Mutation	NA	S1038P	0.47
KIRP	chr7	40078102	Frame_Shift_Del	novel	L960*	0.48
LAML	chr7	40094831	Missense_Mutation	novel	G1464C	0.09
LAML	chr7	39988229	Silent	novel	P614P	0.14
LGG	chr7	40094967	In_Frame_Ins	novel	G1509_L1510insK	0.07
LGG	chr7	40063045	Missense_Mutation	NA	T909A	0.16
LGG	chr7	39987800	Silent	rs779234602	A471A	0.62
LIHC	chr7	40045954	Silent	NA	G824G	0.47
LIHC	chr7	40062833	Missense_Mutation	novel	Y870N	0.13
LIHC	chr7	40094165	Missense_Mutation	novel	I1242L	0.37
LIHC	chr7	40094395	Silent	novel	E1318E	0.25
LIHC	chr7	39987809	Silent	NA	A474A	0.4
LUAD	chr7	40092766	Intron	novel		0.14
LUAD	chr7	39987716	Silent	novel	L443L	0.39
LUAD	chr7	40088268	Missense_Mutation	NA	T1058A	0.1
LUAD	chr7	39999486	Frame_Shift_Del	novel	*D724Ifs8**	0.28
LUAD	chr7	40063036	Nonsense_Mutation	NA	E906*	0.32
LUAD	chr7	39997572	Silent	NA	P650P	0.35
LUAD	chr7	40094519	Missense_Mutation	NA	A1360P	0.28
LUAD	chr7	40047828	Missense_Mutation	NA	I851L	0.24
LUSC	chr7	39999466	Silent	rs151007323	Y716Y	0.26
LUSC	chr7	39997571	Missense_Mutation	NA	P650L	0.14
LUSC	chr7	40063057	Missense_Mutation	rs368244089	I913V	0.27
LUSC	chr7	40047873	Nonsense_Mutation	novel	E866*	0.21
LUSC	chr7	40002013	Missense_Mutation	novel	D779Y	0.64
LUSC	chr7	40078770	Missense_Mutation	NA	P983R	0.13
LUSC	chr7	40094873	Missense_Mutation	novel	G1478R	0.1
LUSC	chr7	39988142	Silent	novel	K585K	0.67
LUSC	chr7	40063072	Missense_Mutation	NA	Q918E	0.41
LUSC	chr7	40094601	Missense_Mutation	NA	S1387F	0.42
LUSC	chr7	40094364	Missense_Mutation	novel	Q1308R	0.16
LUSC	chr7	40094512	Silent	NA	S1357S	0.34
LUSC	chr7	39987721	Missense_Mutation	novel	L445Q	0.47
LUSC	chr7	40078820	Missense_Mutation	novel	D1000Y	0.66
OV	chr7	40088332	Splice_Site	NA	X1079_splice	0.55
OV	chr7	40092538	Intron	novel		1
OV	chr7	40092723	Intron	novel		0.06
OV	chr7	40088244	Missense_Mutation	NA	G1050C	0.25
OV	chr7	39987716	Frame_Shift_Ins	novel	*T444Yfs5**	0.19
OV	chr7	40062877	Silent	NA	L884L	0.15
OV	chr7	40078120	Missense_Mutation	novel	F966I	0.07
OV	chr7	40078094	Missense_Mutation	NA	R957P	0.34
OV	chr7	40062848	Missense_Mutation	NA	I875V	0.07
PAAD	chr7	39951840	Missense_Mutation	novel	S400I	0.15
PRAD	chr7	40046027	Splice_Site	NA	X848_splice	0.23
PRAD	chr7	39951741	Frame_Shift_Del	novel	*S369Afs75**	0.12
PRAD	chr7	40062832	Silent	rs145734382	P869P	0.09
PRAD	chr7	39999416	Missense_Mutation	NA	R700G	0.28
PRAD	chr7	40093129	Missense_Mutation	NA	Q1194E	0.16
PRAD	chr7	40094206	Silent	novel	L1255L	0.35
READ	chr7	40094535	Missense_Mutation	NA	R1365Q	0.29
READ	chr7	40092717	Intron	novel		0.06
READ	chr7	40094949	Missense_Mutation	novel	G1503A	0.11
READ	chr7	40094542	Missense_Mutation	novel	S1367R	0.2
READ	chr7	40094381	Missense_Mutation	NA	D1314Y	0.19
READ	chr7	39997626	Missense_Mutation	NA	K668N	0.31
SARC	chr7	40095128	3'UTR	novel		0.13
SARC	chr7	40088172	Nonsense_Mutation	novel	R1026*	0.39
SARC	chr7	40094429	Missense_Mutation	rs527978475	V1330M	0.18
SKCM	chr7	40047856	Missense_Mutation	NA	R860Q	0.44
SKCM	chr7	40001977	Missense_Mutation	NA	M767L	0.16
SKCM	chr7	40062830	Missense_Mutation	NA	P869S	0.28
SKCM	chr7	39997555	Missense_Mutation	NA	L645F	0.13
SKCM	chr7	39987615	Nonsense_Mutation	rs760503314	R410*	0.53
SKCM	chr7	39951766	Silent	novel	S375S	0.16
SKCM	chr7	40001914	Missense_Mutation	NA	P746T	0.37
SKCM	chr7	40045897	Silent	NA	G805G	0.97
SKCM	chr7	39997579	Missense_Mutation	NA	P653S	0.4
SKCM	chr7	39987886	Missense_Mutation	NA	T500M	0.41
SKCM	chr7	40046010	Missense_Mutation	NA	I843N	0.15
SKCM	chr7	40094418	Missense_Mutation	NA	G1326E	0.27
SKCM	chr7	40094480	Missense_Mutation	NA	A1347P	0.42
SKCM	chr7	40094183	Missense_Mutation	novel	E1248K	0.46
SKCM	chr7	40001955	Silent	NA	L759L	0.28
STAD	chr7	40094597	Missense_Mutation	NA	H1386D	0.19
STAD	chr7	40093233	Silent	NA	V1228V	0.16
STAD	chr7	39951819	Missense_Mutation	NA	R393H	0.08
STAD	chr7	39987630	Missense_Mutation	NA	Y415H	0.1
STAD	chr7	40092938	Missense_Mutation	novel	N1130I	0.13
STAD	chr7	40093191	Silent	rs201950690	A1214A	0.26
STAD	chr7	40093176	Silent	NA	G1209G	0.21
STAD	chr7	40092679	Intron	novel		0.32
STAD	chr7	40093007	Missense_Mutation	NA	S1153L	0.31
STAD	chr7	40094393	Nonsense_Mutation	NA	E1318*	0.44
STAD	chr7	39951810	Missense_Mutation	novel	S390N	0.29
STAD	chr7	40094866	Silent	rs763973066	L1475L	0.13
STAD	chr7	40078759	Silent	NA	L979L	0.33
STAD	chr7	40094761	Silent	NA	S1440S	0.14
STAD	chr7	40078735	Silent	rs149612730	A971A	0.25
STAD	chr7	40094837	Missense_Mutation	NA	L1466V	0.07
STAD	chr7	40063048	Frame_Shift_Del	NA	*K911Nfs13**	0.23
STAD	chr7	40092790	Missense_Mutation	NA	T1081A	0.17
STAD	chr7	40094850	Missense_Mutation	rs776784082	P1470L	0.37
STAD	chr7	39997588	Missense_Mutation	NA	P656S	0.21
STAD	chr7	40092958	Missense_Mutation	NA	A1137T	0.22
STAD	chr7	40093185	Silent	NA	H1212H	0.19
STAD	chr7	40093220	Missense_Mutation	NA	P1224H	0.13
STAD	chr7	40001877	Frame_Shift_Del	rs780713745	*V736Yfs32**	0.31
STAD	chr7	40094638	Frame_Shift_Ins	novel	*P1401Sfs20**	0.17
THCA	chr7	39988213	Missense_Mutation	rs200341630	P609L	0.34
UCEC	chr7	39988093	Missense_Mutation	NA	K569T	0.34
UCEC	chr7	40001863	Nonsense_Mutation	novel	E729*	0.23
UCEC	chr7	40095286	3'UTR	novel		0.45
UCEC	chr7	40088183	Silent	NA	K1029K	0.4
UCEC	chr7	39999375	Missense_Mutation	novel	R686H	0.43
UCEC	chr7	40094391	Missense_Mutation	NA	R1317I	0.34
UCEC	chr7	39988136	Silent	novel	K583K	0.38
UCEC	chr7	40045942	Missense_Mutation	novel	Q820H	0.42
UCEC	chr7	40078096	Nonsense_Mutation	novel	R958*	0.32
UCEC	chr7	40092967	Frame_Shift_Ins	novel	*Q1142Tfs28**	0.33
UCEC	chr7	39987724	Missense_Mutation	novel	K446R	0.44
UCEC	chr7	40094422	Silent	novel	D1327D	0.48
UCEC	chr7	40093008	Silent	rs778552078	S1153S	0.49
UCEC	chr7	40078739	Missense_Mutation	NA	D973N	0.45
UCEC	chr7	40094461	Silent	novel	G1340G	0.3
UCEC	chr7	40095313	3'UTR	novel		0.44
UCEC	chr7	40063090	Nonsense_Mutation	novel	E924*	0.22
UCEC	chr7	40078017	Silent	NA	G931G	0.2
UCEC	chr7	40078070	Missense_Mutation	NA	T949I	0.32
UCEC	chr7	40062828	Missense_Mutation	novel	R868Q	0.09
UCEC	chr7	40094199	Missense_Mutation	rs150957134	R1253Q	0.14
UCEC	chr7	40092821	Missense_Mutation	novel	E1091G	0.15
UCEC	chr7	40094574	Missense_Mutation	novel	D1378G	0.22
UCEC	chr7	40088220	Missense_Mutation	NA	A1042S	0.13
UCEC	chr7	40092721	Intron	novel		0.4
UCEC	chr7	40093008	Silent	rs778552078	S1153S	0.33
UCEC	chr7	40094192	Missense_Mutation	rs142580514	R1251W	0.52
UCEC	chr7	40094378	Missense_Mutation	NA	D1313N	0.41
UCEC	chr7	40095127	3'UTR	novel		0.34
UCEC	chr7	40095009	3'UTR	novel		0.09
UCEC	chr7	40095010	3'UTR	novel		0.09
UCEC	chr7	39987742	Missense_Mutation	novel	E452G	0.32
UCEC	chr7	40045975	Missense_Mutation	NA	K831N	0.47
UCEC	chr7	40095415	3'UTR	novel		0.33
UCEC	chr7	39988213	Missense_Mutation	novel	P609Q	0.27
UCEC	chr7	39988007	Silent	novel	K540K	0.14
UCEC	chr7	39987629	Silent	rs202080779	P414P	0.44
UCEC	chr7	40094647	Silent	NA	S1402S	0.4
UCEC	chr7	40095180	3'UTR	novel		0.4
UCEC	chr7	40094228	Missense_Mutation	rs781231247	E1263K	0.52
UCEC	chr7	40094949	Nonsense_Mutation	novel	*G1503_R1504insKL**	0.12
UCEC	chr7	40095135	3'UTR	rs532268529		0.93
UCEC	chr7	39997530	Missense_Mutation	novel	K636N	0.18
UCEC	chr7	40092996	Missense_Mutation	novel	Q1149H	0.26
UCEC	chr7	39987973	Missense_Mutation	novel	G529D	0.39
UCEC	chr7	40094696	Missense_Mutation	novel	F1419L	0.12
UCEC	chr7	40069383	Intron	novel		0.38
UCEC	chr7	40095123	3'UTR	novel		0.1
UCEC	chr7	39999375	Missense_Mutation	novel	R686H	0.28
UCEC	chr7	40063036	Missense_Mutation	novel	E906K	0.37
UCEC	chr7	40092786	Splice_Region	rs140965963	V1079V	0.43
UCEC	chr7	39987928	Missense_Mutation	novel	D514G	0.28
UCEC	chr7	40078064	Missense_Mutation	novel	F947S	0.38
UCEC	chr7	40094809	Missense_Mutation	novel	K1456N	0.37
UCEC	chr7	40095181	3'UTR	novel		0.3
UCEC	chr7	40045975	Missense_Mutation	NA	K831N	0.43
UCEC	chr7	40094454	Missense_Mutation	novel	N1338S	0.36
UCEC	chr7	39987649	Missense_Mutation	NA	R421K	0.29
UCEC	chr7	40045896	Missense_Mutation	novel	G805V	0.13
UCEC	chr7	40092979	Missense_Mutation	novel	D1144Y	0.45
UCEC	chr7	39999417	Missense_Mutation	NA	R700H	0.28
UCEC	chr7	40063055	Missense_Mutation	novel	P912H	0.4
UCEC	chr7	40078762	Silent	novel	A980A	0.32
UCEC	chr7	40094567	In_Frame_Ins	novel	S1376delinsYGNP	0.07
UCEC	chr7	40094949	Nonsense_Mutation	novel	*R1504Kfs2**	0.09
UCEC	chr7	40088220	Frame_Shift_Ins	novel	*R1044Qfs10**	0.24
UCEC	chr7	40093120	Missense_Mutation	novel	I1191L	0.58
UCEC	chr7	40095007	3'UTR	novel		0.23
UCEC	chr7	40001933	Missense_Mutation	NA	E752G	0.47
UCEC	chr7	40093007	Missense_Mutation	NA	S1153L	0.45
UCEC	chr7	40094389	Missense_Mutation	NA	K1316N	0.43
UCEC	chr7	40094535	Missense_Mutation	NA	R1365Q	0.39
UCEC	chr7	40095136	3'UTR	novel		0.42
UCEC	chr7	40095001	3'UTR	novel		0.15
UCEC	chr7	40063090	Nonsense_Mutation	novel	E924*	0.16
UCEC	chr7	39997594	Nonsense_Mutation	novel	G658*	0.19
UCEC	chr7	39999443	Missense_Mutation	novel	G709R	0.19
UCEC	chr7	40095085	3'UTR	novel		0.23
UCEC	chr7	40095196	3'UTR	novel		0.2
UCEC	chr7	40093097	Missense_Mutation	novel	F1183C	0.16
UCEC	chr7	39951787	Silent	novel	V382V	0.49
UCEC	chr7	40002033	Splice_Site	novel	X785_splice	0.64
UCEC	chr7	40078840	Missense_Mutation	novel	M1006I	0.23
UCEC	chr7	39997550	Missense_Mutation	NA	R643Q	0.1
UCEC	chr7	40001877	Frame_Shift_Del	rs780713745	*V736Yfs32**	0.3
UCEC	chr7	40001887	Missense_Mutation	novel	R737C	0.27
UCEC	chr7	40078735	Silent	rs149612730	A971A	0.33

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
THCA	DEL	0	0.27619

Survival Analysis

Cancer	P-value	Q-value
COAD	0.04	Kaplan-Meier Survival Analysis
PAAD	0.022	Kaplan-Meier Survival Analysis
LAML	0.03	Kaplan-Meier Survival Analysis
KICH	0.021	Kaplan-Meier Survival Analysis
LIHC	0.023	Kaplan-Meier Survival Analysis
LGG	0.0001	Kaplan-Meier Survival Analysis
CHOL	0.01	Kaplan-Meier Survival Analysis
UVM	0.03	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742