EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000066279 (Gene tree)
Gene ID: 259266
Gene Symbol: ASPM
Alias: Calmbp1|ASP|FLJ10517|FLJ10549|MCPH5
Full Name: abnormal spindle microtubule assembly
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 62,568 bases
Position: chr1:197,084,127-197,146,694
Accession: 19048
RBP type: non-canonical RBP
Summary: This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation, with a preferential role in regulating neurogenesis. Mutations in this gene are associated with microcephaly primary type 5. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000367409	ASPM-203	10887	-	ENSP00000356379	3477 (aa)	-	Q8IZT6
ENST00000367408	ASPM-202	3747	-	ENSP00000356378	1142 (aa)	-	Q5VYL4
ENST00000294732	ASPM-201	6132	-	ENSP00000294732	1892 (aa)	-	Q8IZT6

Gene Model

Click here to download ENSG00000066279's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000066279	Macular Degeneration	3.647555E-9	-
ENSG00000066279	Macular Degeneration	3.647555E-9	-
ENSG00000066279	Macular Degeneration	3.647555E-9	-
ENSG00000066279	Macular Degeneration	3.985953E-9	-
ENSG00000066279	Macular Degeneration	4.569571E-9	-
ENSG00000066279	Macular Degeneration	5.967E-6	-
ENSG00000066279	Macular Degeneration	5.967E-6	-
ENSG00000066279	Macular Degeneration	5.967E-6	-
ENSG00000066279	Macular Degeneration	6.47E-6	-
ENSG00000066279	Macular Degeneration	7.66E-12	-
ENSG00000066279	Macular Degeneration	4.45E-14	-
ENSG00000066279	Macular Degeneration	6.24E-11	20385819
ENSG00000066279	Macular Degeneration	7.455E-13	20385819
ENSG00000066279	Platelet Function Tests	5.8900000E-007	-
ENSG00000066279	Platelet Function Tests	6.2700000E-007	-
ENSG00000066279	Platelet Function Tests	5.3200000E-007	-
ENSG00000066279	Platelet Function Tests	6.0100000E-007	-
ENSG00000066279	Platelet Function Tests	6.5000000E-007	-
ENSG00000066279	Platelet Function Tests	6.0700000E-006	-
ENSG00000066279	Magnesium	3.5860000E-005	-
ENSG00000066279	Blood Coagulation Factors	2E-30	23381943

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000066279	rs10922162	1	197101646	C	End-stage coagulation	23381943	[0.43-0.61] unit increase	0.521	EFO_0004634

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000066279's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001764	neuron migration	-	IEA	Process
GO:0002052	positive regulation of neuroblast proliferation	-	IEA	Process
GO:0005516	calmodulin binding	-	IEA	Function
GO:0005634	nucleus	21044324.	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0005813	centrosome	-	IEA	Component
GO:0007051	spindle organization	21044324.	IMP	Process
GO:0007283	spermatogenesis	-	IEA	Process
GO:0008584	male gonad development	-	IEA	Process
GO:0016324	apical plasma membrane	-	IEA	Component
GO:0021873	forebrain neuroblast division	-	IEA	Process
GO:0021987	cerebral cortex development	-	IEA	Process
GO:0030496	midbody	-	IEA	Component
GO:0036449	microtubule minus-end	21044324.	IDA	Component
GO:0045665	negative regulation of neuron differentiation	-	IEA	Process
GO:0045769	negative regulation of asymmetric cell division	-	IEA	Process
GO:0048477	oogenesis	-	IEA	Process
GO:0048589	developmental growth	-	IEA	Process
GO:0051445	regulation of meiotic cell cycle	-	IEA	Process
GO:0051653	spindle localization	21044324.	IMP	Process
GO:0051661	maintenance of centrosome location	-	IEA	Process
GO:0072687	meiotic spindle	-	IEA	Component
GO:0090263	positive regulation of canonical Wnt signaling pathway	-	IEA	Process
GO:0090306	spindle assembly involved in meiosis	-	IEA	Process
GO:0097150	neuronal stem cell population maintenance	-	IEA	Process
GO:0097431	mitotic spindle pole	15972725.21044324.	IDA	Component

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
17090670	Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target.	Proc Natl Acad Sci U S A	2006 Nov 14	Horvath S	-
27876500	Strong correlation between ASPM gene expression and HCV cirrhosis progression identified by co-expression analysis.	Dig Liver Dis	2017 Jan	Wang F	doi: 10.1016/j.dld.2016.10.017
25796627	Enhancement of tumor initiation and expression of KCNMA1, MORF4L2 and ASPM genes in the adenocarcinoma of lung xenograft after vorinostat treatment.	Oncotarget	2015 Apr 20	Kuo WY	-
24830737	Deregulation of microcephalin and ASPM expression are correlated with epithelial ovarian cancer progression.	PLoS One	2014 May 15	Alsiary R	doi: 10.1371/journal.pone.0097059
30266990	ASPM promotes prostate cancer stemness and progression by augmenting Wnt-Dvl-3-β-catenin signaling.	Oncogene	2019 Feb	Pai VC	doi: 10.1038/s41388-018-0497-4

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr1	197102006	Missense_Mutation	novel	Q2415H	0.61
ACC	chr1	197104102	Frame_Shift_Del	rs199422167	I1717*	0.37
ACC	chr1	197090865	Silent	novel	G3207G	0.36
ACC	chr1	197143987	Silent	novel	L137L	0.34
ACC	chr1	197090894	Missense_Mutation	rs760292134	R3198C	0.32
BLCA	chr1	197091952	Silent	novel	A3133A	0.16
BLCA	chr1	197090278	Silent	novel	L3249L	0.12
BLCA	chr1	197104743	Missense_Mutation	NA	A1503V	0.12
BLCA	chr1	197101195	Missense_Mutation	novel	Q2686E	0.24
BLCA	chr1	197100956	Silent	novel	K2765K	0.15
BLCA	chr1	197102255	Silent	novel	R2332R	0.14
BLCA	chr1	197142667	Missense_Mutation	rs775591782	E529Q	0.24
BLCA	chr1	197103999	Missense_Mutation	rs752671920	Q1751R	0.3
BLCA	chr1	197102216	Missense_Mutation	novel	F2345L	0.13
BLCA	chr1	197103871	Missense_Mutation	novel	Q1794E	0.06
BLCA	chr1	197146212	Missense_Mutation	novel	E76Q	0.17
BLCA	chr1	197143681	Missense_Mutation	NA	P191S	0.82
BLCA	chr1	197104829	Nonsense_Mutation	rs147622433	W1474*	0.58
BLCA	chr1	197088427	Missense_Mutation	novel	E3330D	0.47
BLCA	chr1	197091032	Nonsense_Mutation	rs587783292	R3152*	0.24
BLCA	chr1	197104239	Missense_Mutation	novel	S1671Y	0.42
BLCA	chr1	197103275	Missense_Mutation	NA	I1992M	0.27
BLCA	chr1	197129232	Silent	novel	L905L	0.05
BLCA	chr1	197101382	Missense_Mutation	NA	E2623D	0.52
BLCA	chr1	197143099	Missense_Mutation	NA	E385Q	0.16
BLCA	chr1	197093102	Frame_Shift_Ins	rs749449214	*S3082Ifs42**	0.13
BLCA	chr1	197102859	Missense_Mutation	novel	Q2131P	0.07
BLCA	chr1	197101469	Silent	NA	Q2594Q	0.17
BLCA	chr1	197090072	Missense_Mutation	NA	R3281K	0.27
BLCA	chr1	197094181	Splice_Site	novel	X2996_splice	0.08
BLCA	chr1	197101123	Missense_Mutation	novel	T2710A	0.18
BLCA	chr1	197088216	Intron	novel		0.05
BLCA	chr1	197101789	Missense_Mutation	novel	Q2488E	0.22
BLCA	chr1	197143767	Missense_Mutation	novel	S162C	0.09
BLCA	chr1	197143510	Missense_Mutation	novel	S248P	0.3
BLCA	chr1	197146265	Missense_Mutation	rs772380769	G58E	0.77
BLCA	chr1	197104401	Missense_Mutation	novel	R1617L	0.25
BLCA	chr1	197103437	Silent	NA	R1938R	0.26
BLCA	chr1	197103465	Missense_Mutation	novel	Q1929P	0.18
BRCA	chr1	197102551	Missense_Mutation	novel	Q2234E	0.08
BRCA	chr1	197102782	Missense_Mutation	novel	K2157E	0.06
BRCA	chr1	197143455	Missense_Mutation	novel	V266A	0.08
BRCA	chr1	197143355	Silent	NA	T299T	0.36
BRCA	chr1	197122593	Frame_Shift_Ins	novel	*E1132Cfs32**	0.07
BRCA	chr1	197090876	Missense_Mutation	NA	F3204I	0.17
BRCA	chr1	197102169	Missense_Mutation	NA	S2361F	0.4
BRCA	chr1	197133482	Missense_Mutation	novel	N763D	0.04
BRCA	chr1	197142818	Missense_Mutation	novel	I478M	0.12
BRCA	chr1	197133453	Silent	novel	L772L	0.07
BRCA	chr1	197100440	Missense_Mutation	NA	I2937M	0.15
BRCA	chr1	197103541	In_Frame_Del	novel	T1874_K1903del	0.07
BRCA	chr1	197096101	Missense_Mutation	NA	Q2962E	0.11
BRCA	chr1	197142689	Silent	NA	L521L	0.34
BRCA	chr1	197092018	Silent	NA	F3111F	0.43
BRCA	chr1	197103793	Missense_Mutation	novel	L1820I	0.04
BRCA	chr1	197105055	Missense_Mutation	novel	T1399K	0.09
BRCA	chr1	197102088	Nonsense_Mutation	novel	*A2388Efs3**	0.08
BRCA	chr1	197124918	Silent	novel	H1040H	0.08
BRCA	chr1	197086955	Frame_Shift_Del	NA	*V3395Lfs18**	0.22
BRCA	chr1	197100443	Silent	NA	T2936T	0.31
BRCA	chr1	197101778	Missense_Mutation	rs767778442	F2491L	0.26
BRCA	chr1	197143378	Missense_Mutation	novel	E292K	0.14
BRCA	chr1	197102700	Missense_Mutation	rs200848981	R2184Q	0.3
BRCA	chr1	197091930	Missense_Mutation	rs758168416	V3141I	0.1
BRCA	chr1	197104067	Missense_Mutation	NA	M1728I	0.4
BRCA	chr1	197104829	Nonsense_Mutation	rs147622433	W1474*	0.52
BRCA	chr1	197130046	Missense_Mutation	NA	G833E	0.1
BRCA	chr1	197144101	Splice_Site	NA	X100_splice	0.16
BRCA	chr1	197088232	Intron	novel		0.2
BRCA	chr1	197094107	Missense_Mutation	NA	H3021D	0.15
BRCA	chr1	197100460	Missense_Mutation	NA	E2931Q	0.19
BRCA	chr1	197125186	Missense_Mutation	NA	T981N	0.17
BRCA	chr1	197129190	Missense_Mutation	NA	F919L	0.19
BRCA	chr1	197093195	Missense_Mutation	rs142024644	R3051W	0.38
BRCA	chr1	197101665	Missense_Mutation	NA	R2529K	0.18
BRCA	chr1	197105071	Missense_Mutation	rs759544893	L1394I	0.25
BRCA	chr1	197139844	Missense_Mutation	NA	S650Y	0.14
BRCA	chr1	197117858	Missense_Mutation	NA	Q1332H	0.15
BRCA	chr1	197089945	Silent	NA	L3323L	0.41
BRCA	chr1	197104653	Missense_Mutation	novel	N1533I	0.04
BRCA	chr1	197104654	Missense_Mutation	novel	N1533H	0.04
BRCA	chr1	197143205	Silent	novel	Q349Q	0.09
BRCA	chr1	197133581	Missense_Mutation	NA	L730I	0.25
BRCA	chr1	197104283	Silent	NA	L1656L	0.12
BRCA	chr1	197103266	Silent	novel	K1995K	0.16
BRCA	chr1	197101330	Frame_Shift_Del	novel	*I2640Efs7**	0.2
BRCA	chr1	197142663	Missense_Mutation	novel	K530T	0.24
BRCA	chr1	197133494	Silent	NA	R759R	0.35
CESC	chr1	197102565	Missense_Mutation	rs745714332	R2229T	0.18
CESC	chr1	197100679	Nonsense_Mutation	NA	Q2858*	0.31
CESC	chr1	197104381	Frame_Shift_Ins	novel	*K1624Efs21**	0.11
CESC	chr1	197142341	Missense_Mutation	novel	K637N	0.13
CESC	chr1	197090993	Missense_Mutation	novel	H3165Y	0.22
CESC	chr1	197125161	Nonsense_Mutation	rs199422152	W989*	0.3
CESC	chr1	197103815	Silent	rs760048482	Y1812Y	0.45
CESC	chr1	197090327	Missense_Mutation	NA	R3233Q	0.14
CESC	chr1	197104228	Missense_Mutation	NA	F1675L	0.33
CESC	chr1	197103086	Silent	novel	R2055R	0.39
CESC	chr1	197129211	Silent	NA	L912L	0.1
CESC	chr1	197102114	Silent	NA	Q2379Q	0.12
CESC	chr1	197104714	Frame_Shift_Del	novel	*S1513Pfs3**	0.08
CESC	chr1	197104716	Frame_Shift_Del	novel	*E1512Gfs4**	0.08
CESC	chr1	197090328	Nonsense_Mutation	rs199422194	R3233*	0.35
CESC	chr1	197101182	Missense_Mutation	rs191126815	R2690Q	0.12
CESC	chr1	197128519	Silent	rs779286889	A969A	0.32
CESC	chr1	197128650	Missense_Mutation	novel	L926I	0.33
CESC	chr1	197094166	Missense_Mutation	novel	R3001T	0.16
CESC	chr1	197100946	Missense_Mutation	novel	I2769F	0.4
CESC	chr1	197122237	Silent	novel	R1221R	0.22
CESC	chr1	197102063	Silent	novel	R2396R	0.17
CESC	chr1	197139786	Silent	novel	F669F	0.11
CESC	chr1	197101557	Missense_Mutation	NA	R2565K	0.13
CESC	chr1	197084281	3'UTR	novel		0.09
CESC	chr1	197143341	Missense_Mutation	NA	S304L	0.23
CESC	chr1	197146212	Missense_Mutation	NA	E76K	0.48
CESC	chr1	197135192	Missense_Mutation	novel	E693K	0.43
CESC	chr1	197125189	Missense_Mutation	rs751556744	R980Q	0.18
CHOL	chr1	197146378	Silent	NA	P20P	0.11
COAD	chr1	197139780	Frame_Shift_Del	NA	*K671Nfs3**	0.21
COAD	chr1	197100938	Silent	NA	N2771N	0.54
COAD	chr1	197093252	Missense_Mutation	NA	A3032T	0.67
COAD	chr1	197101355	Missense_Mutation	NA	Q2632H	0.34
COAD	chr1	197117871	Missense_Mutation	NA	R1328I	0.39
COAD	chr1	197104777	Missense_Mutation	NA	V1492I	0.19
COAD	chr1	197103635	Frame_Shift_Ins	NA	*L1872Ffs24**	0.43
COAD	chr1	197101024	Nonsense_Mutation	rs774702591	R2743*	0.08
COAD	chr1	197102256	Missense_Mutation	rs758752317	R2332Q	0.12
COAD	chr1	197104242	Missense_Mutation	novel	V1670A	0.27
COAD	chr1	197130044	Nonsense_Mutation	novel	E834*	0.32
COAD	chr1	197143334	Missense_Mutation	novel	L306F	0.27
COAD	chr1	197117932	Missense_Mutation	novel	A1308S	0.05
COAD	chr1	197103714	Missense_Mutation	novel	S1846Y	0.22
COAD	chr1	197143270	Missense_Mutation	novel	A328T	0.07
COAD	chr1	197104211	Frame_Shift_Ins	novel	*N1680Kfs11**	0.33
COAD	chr1	197090339	Frame_Shift_Ins	novel	*I3229Nfs2**	0.48
COAD	chr1	197101182	Missense_Mutation	rs191126815	R2690Q	0.37
COAD	chr1	197102159	Missense_Mutation	novel	I2364M	0.07
COAD	chr1	197124873	Silent	NA	F1055F	0.29
COAD	chr1	197096021	Silent	novel	F2988F	0.28
COAD	chr1	197084204	3'UTR	novel		0.47
COAD	chr1	197142932	Missense_Mutation	NA	E440D	0.42
COAD	chr1	197090233	Silent	novel	K3264K	0.34
COAD	chr1	197102046	Missense_Mutation	rs755628713	R2402T	0.59
COAD	chr1	197084205	3'UTR	novel		0.32
COAD	chr1	197101393	Frame_Shift_Ins	NA	*Q2620Tfs17**	0.19
COAD	chr1	197102470	Frame_Shift_Del	novel	M2261*	0.44
COAD	chr1	197142439	Frame_Shift_Del	novel	*S605Lfs16**	0.24
COAD	chr1	197084205	3'UTR	novel		0.3
COAD	chr1	197104101	Frame_Shift_Ins	NA	*I1717Nfs24**	0.27
COAD	chr1	197122565	Missense_Mutation	NA	G1141S	0.18
COAD	chr1	197125190	Nonsense_Mutation	rs199422151	R980*	0.08
COAD	chr1	197128497	Missense_Mutation	rs750015604	R977C	0.14
COAD	chr1	197102886	Nonsense_Mutation	novel	*F2122delinsCFCYFLL**	0.14
COAD	chr1	197142892	Missense_Mutation	novel	L454I	0.45
COAD	chr1	197142679	Missense_Mutation	NA	V525L	0.41
COAD	chr1	197104942	Missense_Mutation	rs371861473	R1437C	0.36
COAD	chr1	197102455	Missense_Mutation	rs200800956	A2266T	0.47
COAD	chr1	197104137	Missense_Mutation	novel	A1705V	0.1
COAD	chr1	197125082	Missense_Mutation	novel	L1016V	0.29
COAD	chr1	197124892	Nonsense_Mutation	NA	W1049*	0.26
COAD	chr1	197125135	Missense_Mutation	NA	P998L	0.26
COAD	chr1	197084205	3'UTR	novel		0.19
COAD	chr1	197086915	Missense_Mutation	novel	A3407T	0.16
COAD	chr1	197086868	Silent	novel	K3422K	0.4
COAD	chr1	197122473	Silent	novel	C1171C	0.06
COAD	chr1	197104402	Nonsense_Mutation	rs772050241	R1617*	0.2
COAD	chr1	197142472	Missense_Mutation	NA	T594A	0.19
COAD	chr1	197117875	Nonsense_Mutation	NA	R1327*	0.41
COAD	chr1	197101060	Missense_Mutation	NA	E2731K	0.09
COAD	chr1	197103177	Missense_Mutation	novel	V2025A	0.11
COAD	chr1	197104101	Frame_Shift_Ins	NA	*I1717Nfs24**	0.43
COAD	chr1	197124311	Frame_Shift_Del	novel	*N1062Rfs28**	0.1
COAD	chr1	197102712	Missense_Mutation	NA	V2180E	0.28
COAD	chr1	197102871	Missense_Mutation	NA	F2127S	0.2
COAD	chr1	197117845	Missense_Mutation	NA	M1337L	0.11
COAD	chr1	197142428	Silent	NA	E608E	0.12
COAD	chr1	197143003	Missense_Mutation	NA	N417D	0.1
COAD	chr1	197101162	Missense_Mutation	NA	S2697P	0.37
COAD	chr1	197101807	Silent	NA	R2482R	0.32
COAD	chr1	197103085	Missense_Mutation	NA	A2056T	0.3
COAD	chr1	197142356	Missense_Mutation	NA	E632D	0.41
COAD	chr1	197122160	Frame_Shift_Del	novel	*K1247Rfs21**	0.46
COAD	chr1	197101206	Missense_Mutation	rs777169562	R2682Q	0.33
COAD	chr1	197104519	Nonsense_Mutation	NA	R1578*	0.33
COAD	chr1	197103287	Silent	NA	K1988K	0.36
COAD	chr1	197101393	Frame_Shift_Ins	novel	*Q2620Nfs22**	0.15
COAD	chr1	197086957	Missense_Mutation	NA	S3393P	0.32
COAD	chr1	197088230	Intron	novel		0.24
COAD	chr1	197102933	Silent	NA	G2106G	0.36
COAD	chr1	197104596	Missense_Mutation	NA	K1552I	0.3
COAD	chr1	197100629	Missense_Mutation	novel	Q2874H	0.24
COAD	chr1	197101993	Missense_Mutation	NA	S2420P	0.14
COAD	chr1	197102839	Missense_Mutation	NA	T2138A	0.27
COAD	chr1	197104851	Missense_Mutation	NA	S1467F	0.07
COAD	chr1	197146229	Missense_Mutation	novel	P70H	0.1
COAD	chr1	197103623	Frame_Shift_Del	novel	*A1877Lfs2**	0.46
COAD	chr1	197100872	Missense_Mutation	rs376057172	M2793I	0.12
COAD	chr1	197143062	Frame_Shift_Del	NA	L397*	0.27
DLBC	chr1	197100622	Missense_Mutation	novel	K2877Q	0.27
DLBC	chr1	197124267	Missense_Mutation	novel	S1078N	0.27
DLBC	chr1	197100879	Missense_Mutation	NA	G2791V	0.22
ESCA	chr1	197121927	Silent	novel	L1286L	0.3
ESCA	chr1	197101826	Missense_Mutation	novel	K2475N	0.13
ESCA	chr1	197128506	Missense_Mutation	novel	C974G	0.08
ESCA	chr1	197096008	Missense_Mutation	novel	E2993K	0.16
ESCA	chr1	197104102	Frame_Shift_Del	rs199422167	I1717*	0.24
ESCA	chr1	197102193	Missense_Mutation	novel	R2353K	0.35
GBM	chr1	197143444	Missense_Mutation	NA	S270P	0.42
GBM	chr1	197091032	Nonsense_Mutation	rs587783292	R3152*	0.35
GBM	chr1	197093193	Silent	novel	R3051R	0.22
GBM	chr1	197094130	Missense_Mutation	novel	A3013V	0.22
GBM	chr1	197101495	Missense_Mutation	novel	K2586Q	0.52
GBM	chr1	197102797	Missense_Mutation	novel	A2152T	0.38
GBM	chr1	197103217	Nonsense_Mutation	NA	E2012*	0.21
GBM	chr1	197129195	Missense_Mutation	rs142655430	E918K	0.42
GBM	chr1	197129918	Missense_Mutation	novel	D876N	0.49
GBM	chr1	197144092	Silent	novel	E102E	0.34
GBM	chr1	197093202	Silent	NA	V3048V	0.59
GBM	chr1	197090295	Nonsense_Mutation	rs199422195	R3244*	0.1
GBM	chr1	197103009	Missense_Mutation	novel	K2081I	0.07
GBM	chr1	197129296	Missense_Mutation	novel	K884M	0.43
GBM	chr1	197129983	Missense_Mutation	novel	R854H	0.43
GBM	chr1	197139869	Splice_Region	novel	L642L	0.26
GBM	chr1	197132321	Missense_Mutation	novel	L817F	0.04
GBM	chr1	197102678	Silent	novel	T2191T	0.26
GBM	chr1	197091941	Missense_Mutation	NA	A3137D	0.4
GBM	chr1	197102236	Missense_Mutation	NA	T2339P	0.11
HNSC	chr1	197100577	Missense_Mutation	novel	H2892Y	0.48
HNSC	chr1	197122194	Missense_Mutation	novel	H1236N	0.21
HNSC	chr1	197090993	Missense_Mutation	novel	H3165D	0.14
HNSC	chr1	197102273	Missense_Mutation	NA	M2326I	0.4
HNSC	chr1	197102913	Missense_Mutation	novel	I2113N	0.41
HNSC	chr1	197122290	Missense_Mutation	novel	E1204Q	0.26
HNSC	chr1	197125186	Missense_Mutation	rs763886024	T981I	0.14
HNSC	chr1	197146387	Missense_Mutation	novel	E17D	0.23
HNSC	chr1	197102483	Missense_Mutation	novel	R2256S	0.17
HNSC	chr1	197103545	Silent	novel	L1902L	0.54
HNSC	chr1	197146315	Silent	novel	L41L	0.16
HNSC	chr1	197101657	Missense_Mutation	novel	H2532Y	0.13
HNSC	chr1	197142783	Missense_Mutation	novel	R490L	0.14
HNSC	chr1	197100873	Missense_Mutation	novel	M2793T	0.3
HNSC	chr1	197142559	Missense_Mutation	NA	S565T	0.25
HNSC	chr1	197122471	Missense_Mutation	rs201067420	T1172M	0.22
HNSC	chr1	197101750	Nonsense_Mutation	NA	Q2501*	0.27
HNSC	chr1	197142586	Missense_Mutation	rs756904112	K556E	0.45
HNSC	chr1	197101817	Silent	novel	Q2478Q	0.19
HNSC	chr1	197102254	Missense_Mutation	novel	E2333K	0.08
HNSC	chr1	197122508	Missense_Mutation	novel	A1160S	0.28
HNSC	chr1	197101788	Missense_Mutation	novel	Q2488P	0.11
HNSC	chr1	197142541	Missense_Mutation	novel	V571L	0.44
HNSC	chr1	197146385	Missense_Mutation	NA	R18Q	0.2
HNSC	chr1	197142417	Missense_Mutation	NA	S612L	0.23
HNSC	chr1	197125097	Missense_Mutation	rs536317935	I1011V	0.25
HNSC	chr1	197103143	Silent	novel	V2036V	0.46
HNSC	chr1	197103957	Missense_Mutation	novel	R1765T	0.22
HNSC	chr1	197102103	Missense_Mutation	novel	R2383T	0.2
HNSC	chr1	197103851	Missense_Mutation	novel	Q1800H	0.39
HNSC	chr1	197143359	Missense_Mutation	NA	L298P	0.39
HNSC	chr1	197105037	Missense_Mutation	rs143092798	R1405H	0.17
KIRC	chr1	197124146	Missense_Mutation	novel	D1118E	0.21
KIRC	chr1	197121938	Missense_Mutation	NA	K1283E	0.25
KIRC	chr1	197121940	Missense_Mutation	NA	L1282P	0.25
KIRC	chr1	197101820	Silent	rs778768318	L2477L	0.18
KIRC	chr1	197117953	Silent	NA	L1301L	0.18
KIRP	chr1	197103160	Missense_Mutation	NA	Y2031H	0.16
KIRP	chr1	197104843	Frame_Shift_Ins	novel	*I1470Yfs7**	0.82
LAML	chr1	197101336	Missense_Mutation	novel	K2639E	0.07
LAML	chr1	197104715	Missense_Mutation	novel	E1512D	0.04
LAML	chr1	197142891	Frame_Shift_Del	novel	*L454Qfs2**	0.05
LAML	chr1	197142657	Missense_Mutation	novel	I532K	0.05
LGG	chr1	197103085	Missense_Mutation	NA	A2056P	0.31
LGG	chr1	197091004	Missense_Mutation	novel	I3161T	0.07
LGG	chr1	197101585	Missense_Mutation	novel	A2556T	0.43
LGG	chr1	197091991	Missense_Mutation	novel	N3120K	0.07
LGG	chr1	197142637	Frame_Shift_Ins	novel	*E539Rfs16**	0.15
LGG	chr1	197084249	3'UTR	novel		0.56
LGG	chr1	197122471	Missense_Mutation	rs201067420	T1172M	0.31
LGG	chr1	197102456	Silent	rs750759285	A2265A	0.3
LGG	chr1	197103442	Nonsense_Mutation	novel	G1937*	0.07
LGG	chr1	197104381	Missense_Mutation	novel	K1624E	0.1
LGG	chr1	197105158	Nonsense_Mutation	novel	Q1365*	0.47
LGG	chr1	197125123	Missense_Mutation	rs749600804	R1002H	0.15
LGG	chr1	197102816	Frame_Shift_Ins	novel	*I2146Ffs6**	0.07
LGG	chr1	197102818	Missense_Mutation	novel	V2145F	0.05
LIHC	chr1	197101393	Frame_Shift_Ins	NA	*Q2620Tfs17**	0.38
LIHC	chr1	197144067	Missense_Mutation	novel	T111A	0.31
LIHC	chr1	197133395	Missense_Mutation	NA	R792W	0.36
LIHC	chr1	197096018	Silent	novel	Y2989Y	0.39
LIHC	chr1	197103231	Missense_Mutation	NA	Y2007S	0.2
LIHC	chr1	197102785	Missense_Mutation	NA	G2156R	0.33
LIHC	chr1	197146541	5'UTR	novel		0.35
LIHC	chr1	197142424	Missense_Mutation	rs769895394	K610E	0.3
LIHC	chr1	197124886	Missense_Mutation	NA	I1051T	0.08
LIHC	chr1	197139858	Missense_Mutation	NA	F645L	0.39
LUAD	chr1	197122490	Missense_Mutation	NA	T1166S	0.24
LUAD	chr1	197103905	Missense_Mutation	novel	Q1782H	0.14
LUAD	chr1	197101560	Missense_Mutation	NA	Y2564C	0.13
LUAD	chr1	197102159	Silent	novel	I2364I	0.08
LUAD	chr1	197104957	Silent	NA	R1432R	0.16
LUAD	chr1	197133494	Missense_Mutation	rs777867809	R759W	0.46
LUAD	chr1	197104659	Missense_Mutation	rs200681905	R1531L	0.12
LUAD	chr1	197132316	Missense_Mutation	NA	Y819C	0.34
LUAD	chr1	197104015	Missense_Mutation	NA	K1746Q	0.61
LUAD	chr1	197102812	Missense_Mutation	NA	Q2147K	0.38
LUAD	chr1	197143465	Missense_Mutation	novel	S263R	0.15
LUAD	chr1	197104794	Missense_Mutation	rs368020945	Y1486C	0.68
LUAD	chr1	197122505	Missense_Mutation	NA	I1161L	0.46
LUAD	chr1	197102173	Missense_Mutation	novel	A2360S	0.13
LUAD	chr1	197102898	Missense_Mutation	NA	R2118M	0.27
LUAD	chr1	197143779	Missense_Mutation	novel	K158R	0.09
LUAD	chr1	197133540	Silent	NA	P743P	0.1
LUAD	chr1	197103238	Silent	novel	R2005R	0.21
LUAD	chr1	197125051	Missense_Mutation	novel	E1026V	0.18
LUAD	chr1	197146487	5'UTR	novel		0.12
LUAD	chr1	197100971	Frame_Shift_Ins	novel	*N2760Kfs12**	0.17
LUAD	chr1	197101511	Silent	novel	T2580T	0.16
LUAD	chr1	197100956	Missense_Mutation	NA	K2765N	0.43
LUAD	chr1	197101711	Missense_Mutation	NA	Y2514N	0.27
LUAD	chr1	197096093	Missense_Mutation	rs201285805	W2964C	0.52
LUAD	chr1	197143533	Missense_Mutation	NA	S240F	0.16
LUAD	chr1	197133522	Silent	NA	E749E	0.35
LUAD	chr1	197102848	Missense_Mutation	novel	S2135G	0.08
LUAD	chr1	197117893	Missense_Mutation	rs758919365	V1321F	0.16
LUAD	chr1	197093084	Missense_Mutation	NA	A3088T	0.52
LUAD	chr1	197135234	Missense_Mutation	NA	R679G	0.29
LUAD	chr1	197093157	Silent	NA	I3063I	0.3
LUAD	chr1	197102294	Silent	rs561930237	Q2319Q	0.05
LUAD	chr1	197105179	Missense_Mutation	NA	W1358G	0.18
LUAD	chr1	197103512	Silent	NA	A1913A	0.15
LUAD	chr1	197093195	Silent	rs142024644	R3051R	0.25
LUAD	chr1	197102036	Missense_Mutation	novel	K2405N	0.51
LUAD	chr1	197093109	Missense_Mutation	rs535630513	F3079L	0.05
LUAD	chr1	197146482	5'UTR	novel		0.1
LUAD	chr1	197088275	Frame_Shift_Del	novel	*K3381Rfs32**	0.54
LUAD	chr1	197088276	Nonsense_Mutation	novel	K3381*	0.54
LUAD	chr1	197135096	Missense_Mutation	NA	V725L	0.2
LUAD	chr1	197102074	Missense_Mutation	NA	A2393S	0.35
LUAD	chr1	197101664	Missense_Mutation	novel	R2529S	0.41
LUAD	chr1	197084405	Missense_Mutation	novel	L3451F	0.13
LUAD	chr1	197142965	Nonsense_Mutation	NA	W429*	0.15
LUAD	chr1	197122510	Missense_Mutation	novel	D1159V	0.27
LUAD	chr1	197146341	Missense_Mutation	novel	A33S	0.13
LUAD	chr1	197096091	Missense_Mutation	rs754886176	Y2965C	0.22
LUAD	chr1	197128533	Missense_Mutation	novel	V965F	0.15
LUAD	chr1	197122468	Missense_Mutation	NA	Q1173P	0.24
LUAD	chr1	197103521	Missense_Mutation	novel	M1910I	0.53
LUAD	chr1	197100448	Missense_Mutation	NA	S2935G	0.22
LUAD	chr1	197146217	Missense_Mutation	novel	V74A	0.11
LUAD	chr1	197100936	Missense_Mutation	NA	Q2772R	0.11
LUAD	chr1	197146500	5'UTR	novel		0.21
LUAD	chr1	197103885	Missense_Mutation	NA	K1789T	0.34
LUAD	chr1	197096125	Missense_Mutation	novel	K2954E	0.27
LUAD	chr1	197103237	Missense_Mutation	novel	R2005M	0.22
LUAD	chr1	197088344	Missense_Mutation	novel	G3358D	0.95
LUAD	chr1	197101656	Missense_Mutation	NA	H2532L	0.3
LUAD	chr1	197132342	Silent	novel	Q810Q	0.13
LUAD	chr1	197146269	Missense_Mutation	novel	L57M	0.24
LUAD	chr1	197102467	Missense_Mutation	NA	M2262L	0.06
LUAD	chr1	197142460	Missense_Mutation	NA	E598Q	0.06
LUAD	chr1	197144000	Missense_Mutation	NA	Q133R	0.19
LUAD	chr1	197132324	Silent	rs565764186	L816L	0.34
LUAD	chr1	197103666	Missense_Mutation	novel	K1862R	0.15
LUAD	chr1	197101699	Missense_Mutation	novel	R2518G	0.13
LUAD	chr1	197124296	Missense_Mutation	novel	E1068D	0.13
LUAD	chr1	197100849	Missense_Mutation	NA	S2801F	0.12
LUAD	chr1	197090365	Missense_Mutation	NA	W3220C	0.14
LUAD	chr1	197143435	Nonsense_Mutation	NA	E273*	0.12
LUAD	chr1	197093218	Missense_Mutation	novel	Y3043F	0.06
LUAD	chr1	197128515	Missense_Mutation	NA	D971Y	0.43
LUAD	chr1	197101645	Missense_Mutation	NA	V2536F	0.06
LUAD	chr1	197104532	Silent	NA	R1573R	0.25
LUAD	chr1	197095998	Missense_Mutation	novel	R2996L	0.19
LUAD	chr1	197101386	Missense_Mutation	NA	Q2622L	0.44
LUAD	chr1	197142394	Missense_Mutation	NA	V620L	0.23
LUAD	chr1	197100725	Silent	novel	R2842R	0.1
LUAD	chr1	197100879	Missense_Mutation	NA	G2791V	0.26
LUAD	chr1	197101350	Missense_Mutation	novel	H2634R	0.36
LUAD	chr1	197101992	Missense_Mutation	rs762895326	S2420L	0.1
LUAD	chr1	197142859	Missense_Mutation	novel	I465V	0.21
LUAD	chr1	197090266	Silent	novel	T3253T	0.14
LUAD	chr1	197104946	Silent	novel	K1435K	0.06
LUAD	chr1	197102195	Missense_Mutation	NA	M2352I	0.06
LUAD	chr1	197146203	Missense_Mutation	novel	I79F	0.12
LUAD	chr1	197104353	Missense_Mutation	NA	R1633P	0.12
LUAD	chr1	197086803	Missense_Mutation	rs751974149	R3444I	0.13
LUAD	chr1	197096109	Missense_Mutation	NA	C2959F	0.3
LUAD	chr1	197103073	Missense_Mutation	NA	K2060E	0.08
LUAD	chr1	197100846	Missense_Mutation	NA	G2802V	0.29
LUSC	chr1	197104547	Silent	NA	S1568S	0.25
LUSC	chr1	197124916	Missense_Mutation	novel	R1041K	0.14
LUSC	chr1	197103392	Silent	novel	V1953V	0.22
LUSC	chr1	197086916	Silent	NA	T3406T	0.21
LUSC	chr1	197117789	Splice_Region	NA	Q1355Q	0.15
LUSC	chr1	197100509	Silent	NA	I2914I	0.07
LUSC	chr1	197143545	Missense_Mutation	rs764828729	C236F	0.55
LUSC	chr1	197103019	Nonsense_Mutation	rs199422168	R2078*	0.1
LUSC	chr1	197090295	Silent	novel	R3244R	0.13
LUSC	chr1	197090298	Frame_Shift_Del	novel	*R3241Sfs22**	0.13
LUSC	chr1	197103482	Silent	NA	A1923A	0.76
LUSC	chr1	197121966	Nonsense_Mutation	novel	*I1273Mfs10**	0.25
LUSC	chr1	197143397	Missense_Mutation	NA	N285K	0.17
LUSC	chr1	197090240	Missense_Mutation	novel	T3262R	0.09
LUSC	chr1	197143568	Silent	NA	F228F	0.28
LUSC	chr1	197122288	Missense_Mutation	NA	E1204D	0.35
LUSC	chr1	197103236	Missense_Mutation	NA	R2005S	0.26
LUSC	chr1	197101350	Missense_Mutation	novel	H2634L	0.49
LUSC	chr1	197105037	Missense_Mutation	rs143092798	R1405L	0.21
LUSC	chr1	197101653	Missense_Mutation	NA	S2533F	0.21
LUSC	chr1	197102875	Missense_Mutation	NA	M2126L	0.2
LUSC	chr1	197143426	Missense_Mutation	NA	V276L	0.19
LUSC	chr1	197104502	Missense_Mutation	novel	K1583N	0.5
LUSC	chr1	197146185	Frame_Shift_Del	novel	*A85Rfs34**	0.38
LUSC	chr1	197146186	Silent	novel	A84A	0.37
LUSC	chr1	197142991	Missense_Mutation	novel	Q421E	0.2
LUSC	chr1	197143143	Missense_Mutation	novel	S370C	0.22
LUSC	chr1	197103649	Missense_Mutation	novel	R1868G	0.1
LUSC	chr1	197143147	Missense_Mutation	novel	D369Y	0.29
LUSC	chr1	197088232	Intron	novel		0.33
LUSC	chr1	197142784	Missense_Mutation	novel	R490S	0.2
LUSC	chr1	197129915	Missense_Mutation	novel	G877C	0.53
LUSC	chr1	197103163	Missense_Mutation	novel	A2030P	0.04
LUSC	chr1	197104752	Frame_Shift_Ins	novel	*C1500Lfs9**	0.14
LUSC	chr1	197100999	Missense_Mutation	novel	G2751V	0.29
LUSC	chr1	197142372	Missense_Mutation	novel	R627P	0.33
LUSC	chr1	197090238	Missense_Mutation	NA	Y3263N	0.21
LUSC	chr1	197129932	Missense_Mutation	NA	P871L	0.27
LUSC	chr1	197129933	Missense_Mutation	NA	P871S	0.27
LUSC	chr1	197143752	Missense_Mutation	novel	R167K	0.32
LUSC	chr1	197102580	Missense_Mutation	NA	W2224S	0.22
LUSC	chr1	197101513	Missense_Mutation	novel	T2580S	0.45
LUSC	chr1	197102283	Missense_Mutation	novel	R2323K	0.42
LUSC	chr1	197101157	Missense_Mutation	NA	F2698L	0.68
LUSC	chr1	197089979	Missense_Mutation	novel	C3312F	0.25
LUSC	chr1	197100789	Frame_Shift_Ins	novel	*I2821Nfs7**	0.09
LUSC	chr1	197104591	Missense_Mutation	novel	H1554D	0.11
LUSC	chr1	197102409	Missense_Mutation	novel	R2281T	0.18
LUSC	chr1	197104064	Silent	novel	R1729R	0.51
LUSC	chr1	197104065	Missense_Mutation	NA	R1729L	0.51
LUSC	chr1	197102633	Missense_Mutation	novel	Q2206H	0.25
LUSC	chr1	197103450	Missense_Mutation	NA	W1934L	0.2
LUSC	chr1	197093225	Missense_Mutation	novel	R3041G	0.28
LUSC	chr1	197122009	Missense_Mutation	novel	R1259M	0.2
LUSC	chr1	197100758	Silent	novel	R2831R	0.11
LUSC	chr1	197090960	Missense_Mutation	NA	E3176Q	0.27
LUSC	chr1	197103564	Missense_Mutation	NA	R1896K	0.2
LUSC	chr1	197103851	Silent	novel	Q1800Q	0.26
LUSC	chr1	197102963	Silent	NA	T2096T	0.28
LUSC	chr1	197142385	Missense_Mutation	rs145625555	P623T	0.23
LUSC	chr1	197146263	Missense_Mutation	novel	A59S	0.56
LUSC	chr1	197103149	Missense_Mutation	NA	M2034I	0.12
LUSC	chr1	197104694	Silent	novel	K1519K	0.41
LUSC	chr1	197100650	Missense_Mutation	NA	Q2867H	0.71
LUSC	chr1	197101542	Missense_Mutation	novel	Y2570F	0.33
LUSC	chr1	197101560	Missense_Mutation	novel	Y2564F	0.07
LUSC	chr1	197142628	Missense_Mutation	rs779017532	H542Y	0.14
MESO	chr1	197128602	Missense_Mutation	rs546095187	R942C	0.07
MESO	chr1	197143457	Frame_Shift_Ins	novel	*N265Kfs8**	0.07
OV	chr1	197104095	Missense_Mutation	NA	A1719V	0.16
OV	chr1	197105126	Silent	novel	I1375I	0.05
OV	chr1	197103537	Missense_Mutation	novel	Q1905R	0.08
OV	chr1	197102919	Missense_Mutation	NA	R2111K	0.29
OV	chr1	197133497	Frame_Shift_Del	novel	*S752Lfs5**	0.13
OV	chr1	197101526	Silent	NA	K2575K	0.1
OV	chr1	197101947	Missense_Mutation	rs749703843	I2435T	0.07
OV	chr1	197102864	Missense_Mutation	novel	M2129I	0.36
OV	chr1	197146140	Splice_Site	NA	X99_splice	0.1
OV	chr1	197102017	Missense_Mutation	novel	T2412A	0.16
OV	chr1	197101614	Missense_Mutation	novel	A2546V	0.07
OV	chr1	197128519	Silent	rs779286889	A969A	0.45
OV	chr1	197092023	Missense_Mutation	novel	H3110D	0.34
PAAD	chr1	197103156	Missense_Mutation	rs149033840	R2032H	0.21
PAAD	chr1	197103029	Silent	NA	Q2074Q	0.03
PAAD	chr1	197143693	Silent	novel	R187R	0.39
PAAD	chr1	197100499	Missense_Mutation	novel	A2918S	0.15
PAAD	chr1	197101987	Silent	novel	L2422L	0.15
PAAD	chr1	197103301	Missense_Mutation	novel	H1984N	0.21
PAAD	chr1	197103403	Missense_Mutation	novel	A1950S	0.26
PAAD	chr1	197103793	Silent	novel	L1820L	0.06
PAAD	chr1	197104883	Nonsense_Mutation	novel	W1456*	0.14
PAAD	chr1	197122007	Missense_Mutation	novel	L1260I	0.07
PAAD	chr1	197128535	Missense_Mutation	novel	A964V	0.16
PAAD	chr1	197142703	Missense_Mutation	novel	A517T	0.16
PAAD	chr1	197101255	Missense_Mutation	novel	T2666A	0.31
PAAD	chr1	197102252	Silent	novel	E2333E	0.17
PCPG	chr1	197100682	Frame_Shift_Del	novel	*V2857Ffs81**	0.08
PRAD	chr1	197135235	Silent	NA	P678P	0.11
PRAD	chr1	197091978	Nonsense_Mutation	novel	Q3125*	0.28
PRAD	chr1	197104223	Missense_Mutation	novel	L1676F	0.09
PRAD	chr1	197122001	Missense_Mutation	novel	D1262N	0.45
READ	chr1	197100743	Missense_Mutation	NA	Q2836H	0.29
READ	chr1	197103217	Nonsense_Mutation	NA	E2012*	0.22
READ	chr1	197103009	Missense_Mutation	NA	K2081R	0.41
READ	chr1	197142572	Silent	rs751204699	N560N	0.4
READ	chr1	197125190	Nonsense_Mutation	rs199422151	R980*	0.54
READ	chr1	197101725	Missense_Mutation	NA	L2509P	0.32
READ	chr1	197143461	Missense_Mutation	rs769866190	A264V	0.28
READ	chr1	197101023	Missense_Mutation	rs202193200	R2743Q	0.43
READ	chr1	197124883	Missense_Mutation	rs550484483	A1052V	0.36
READ	chr1	197142584	Missense_Mutation	NA	K556N	0.46
READ	chr1	197104519	Nonsense_Mutation	NA	R1578*	0.24
READ	chr1	197088371	Missense_Mutation	novel	L3349R	0.26
READ	chr1	197091032	Nonsense_Mutation	rs587783292	R3152*	0.41
SARC	chr1	197102000	Missense_Mutation	novel	R2417S	0.69
SKCM	chr1	197102438	Silent	NA	R2271R	0.34
SKCM	chr1	197104519	Nonsense_Mutation	NA	R1578*	0.43
SKCM	chr1	197146265	Missense_Mutation	novel	G58V	0.37
SKCM	chr1	197146266	Nonsense_Mutation	novel	G58*	0.37
SKCM	chr1	197128602	Missense_Mutation	rs546095187	R942C	0.18
SKCM	chr1	197103280	Missense_Mutation	novel	K1991E	0.46
SKCM	chr1	197090295	Nonsense_Mutation	rs199422195	R3244*	0.19
SKCM	chr1	197105149	Frame_Shift_Del	novel	L1368*	0.77
SKCM	chr1	197104519	Nonsense_Mutation	NA	R1578*	0.2
SKCM	chr1	197133578	Missense_Mutation	NA	L731F	0.19
SKCM	chr1	197092032	Nonsense_Mutation	rs199422187	R3107*	0.75
SKCM	chr1	197101023	Missense_Mutation	rs202193200	R2743Q	0.2
SKCM	chr1	197102941	Missense_Mutation	NA	Y2104H	0.52
SKCM	chr1	197103409	Missense_Mutation	rs375852743	R1948C	0.45
SKCM	chr1	197103410	Silent	novel	L1947L	0.45
SKCM	chr1	197121921	Silent	NA	R1288R	0.54
SKCM	chr1	197103740	Silent	novel	G1837G	0.34
SKCM	chr1	197103857	Silent	novel	F1798F	0.38
SKCM	chr1	197130041	Missense_Mutation	NA	L835I	0.43
SKCM	chr1	197104024	Missense_Mutation	rs201956605	L1743F	0.49
SKCM	chr1	197104756	Missense_Mutation	rs756067585	R1499W	0.17
SKCM	chr1	197143000	Missense_Mutation	NA	E418K	0.5
SKCM	chr1	197103981	Missense_Mutation	NA	S1757L	0.59
SKCM	chr1	197101588	Missense_Mutation	NA	K2555E	0.13
SKCM	chr1	197104986	Missense_Mutation	NA	S1422L	0.16
SKCM	chr1	197133379	Missense_Mutation	rs750028073	R797Q	0.41
SKCM	chr1	197104184	Silent	NA	V1689V	0.19
SKCM	chr1	197142836	Missense_Mutation	NA	F472L	0.32
SKCM	chr1	197101927	Nonsense_Mutation	rs769364943	R2442*	0.32
SKCM	chr1	197104114	Missense_Mutation	rs143911853	R1713C	0.3
SKCM	chr1	197103759	Missense_Mutation	NA	I1831N	0.31
SKCM	chr1	197129238	Silent	rs761223478	S903S	0.51
SKCM	chr1	197135237	Missense_Mutation	NA	P678S	0.26
SKCM	chr1	197102842	Missense_Mutation	novel	H2137Y	0.15
SKCM	chr1	197122290	Nonsense_Mutation	novel	E1204*	0.17
SKCM	chr1	197094092	Missense_Mutation	novel	M3026L	0.15
SKCM	chr1	197102289	Missense_Mutation	NA	S2321L	0.55
SKCM	chr1	197128557	Missense_Mutation	NA	P957S	0.25
SKCM	chr1	197124883	Missense_Mutation	rs550484483	A1052V	0.21
SKCM	chr1	197100495	Missense_Mutation	NA	R2919K	0.49
SKCM	chr1	197103695	In_Frame_Ins	novel	Q1849_I1852dup	0.42
SKCM	chr1	197146505	5'UTR	novel		0.4
SKCM	chr1	197129317	Missense_Mutation	NA	G877V	0.56
SKCM	chr1	197090894	Missense_Mutation	rs760292134	R3198C	0.16
SKCM	chr1	197105057	Silent	NA	V1398V	0.21
SKCM	chr1	197122248	Missense_Mutation	NA	H1218D	0.1
SKCM	chr1	197143413	Missense_Mutation	rs772696379	S280F	0.23
SKCM	chr1	197146280	Missense_Mutation	novel	G53E	0.13
SKCM	chr1	197146281	Missense_Mutation	novel	G53R	0.13
SKCM	chr1	197104703	Silent	NA	T1516T	0.15
SKCM	chr1	197143030	Nonsense_Mutation	NA	Q408*	0.31
SKCM	chr1	197104490	Silent	NA	I1587I	0.13
SKCM	chr1	197142445	Missense_Mutation	NA	H603Y	0.15
SKCM	chr1	197102326	Missense_Mutation	NA	L2309F	0.08
SKCM	chr1	197102362	Missense_Mutation	rs759104234	R2297W	0.24
SKCM	chr1	197104833	Missense_Mutation	NA	S1473L	0.27
SKCM	chr1	197100713	Silent	novel	F2846F	0.14
SKCM	chr1	197096028	Frame_Shift_Del	novel	*G2986Vfs7**	0.1
SKCM	chr1	197117825	Silent	rs138508558	L1343L	0.22
SKCM	chr1	197128627	Silent	NA	F933F	0.49
SKCM	chr1	197100891	Missense_Mutation	rs111685217	V2787A	0.23
SKCM	chr1	197102846	Silent	novel	S2135S	0.35
SKCM	chr1	197093212	Missense_Mutation	rs771829922	G3045E	0.31
SKCM	chr1	197093213	Missense_Mutation	novel	G3045R	0.32
SKCM	chr1	197090895	Silent	novel	L3197L	0.39
SKCM	chr1	197102741	Frame_Shift_Del	novel	*V2172Sfs9**	0.47
SKCM	chr1	197101316	Silent	NA	L2645L	0.27
SKCM	chr1	197103857	Silent	novel	F1798F	0.13
STAD	chr1	197128591	Silent	NA	G945G	0.14
STAD	chr1	197143095	Missense_Mutation	NA	S386L	0.12
STAD	chr1	197100607	Missense_Mutation	rs201732387	Y2882H	0.2
STAD	chr1	197129185	Splice_Site	NA	X920_splice	0.15
STAD	chr1	197104102	Frame_Shift_Del	rs199422167	I1717*	0.71
STAD	chr1	197122493	Missense_Mutation	novel	T1165A	0.17
STAD	chr1	197124908	Frame_Shift_Del	novel	*T1044Lfs8**	0.12
STAD	chr1	197124199	Missense_Mutation	NA	R1101G	0.15
STAD	chr1	197139813	Silent	rs151087446	I660I	0.21
STAD	chr1	197103325	Missense_Mutation	NA	I1976F	0.05
STAD	chr1	197102577	Missense_Mutation	NA	A2225E	0.38
STAD	chr1	197091935	Missense_Mutation	novel	K3139R	0.38
STAD	chr1	197100819	Missense_Mutation	NA	Y2811C	0.25
STAD	chr1	197142428	Silent	NA	E608E	0.26
STAD	chr1	197104102	Frame_Shift_Del	rs199422167	I1717*	0.37
STAD	chr1	197101024	Nonsense_Mutation	rs774702591	R2743*	0.31
STAD	chr1	197100980	Missense_Mutation	NA	K2757N	0.54
STAD	chr1	197090208	Silent	NA	L3273L	0.33
STAD	chr1	197122177	Missense_Mutation	novel	N1241K	0.22
STAD	chr1	197104102	Frame_Shift_Del	rs199422167	I1717*	0.32
STAD	chr1	197130000	Silent	NA	A848A	0.18
STAD	chr1	197088406	Silent	NA	Y3337Y	0.44
STAD	chr1	197100672	Missense_Mutation	NA	K2860T	0.24
STAD	chr1	197143157	Missense_Mutation	rs375572921	I365M	0.51
STAD	chr1	197104638	Missense_Mutation	novel	R1538Q	0.13
STAD	chr1	197143447	Missense_Mutation	novel	V269I	0.36
STAD	chr1	197103642	Frame_Shift_Ins	novel	*H1870Pfs7**	0.09
STAD	chr1	197084301	3'UTR	novel		0.1
STAD	chr1	197102763	Missense_Mutation	NA	Y2163C	0.08
STAD	chr1	197124227	Silent	NA	D1091D	0.07
STAD	chr1	197124925	Missense_Mutation	NA	D1038G	0.05
STAD	chr1	197128497	Missense_Mutation	rs750015604	R977C	0.22
STAD	chr1	197129961	Missense_Mutation	NA	I861M	0.05
STAD	chr1	197142739	Missense_Mutation	NA	T505A	0.06
STAD	chr1	197090909	Missense_Mutation	rs140679756	R3193C	0.25
STAD	chr1	197104212	Frame_Shift_Del	novel	*N1680Mfs4**	0.34
STAD	chr1	197090054	Missense_Mutation	NA	C3287Y	0.59
STAD	chr1	197143515	Frame_Shift_Del	novel	*R242Pfs14**	0.22
STAD	chr1	197102113	Missense_Mutation	NA	H2380Y	0.43
STAD	chr1	197102359	Missense_Mutation	NA	A2298T	0.25
STAD	chr1	197094139	Missense_Mutation	NA	K3010I	0.6
STAD	chr1	197103401	Silent	rs537962201	A1950A	0.3
STAD	chr1	197103266	Frame_Shift_Del	novel	*A1996Lfs4**	0.27
STAD	chr1	197100636	Missense_Mutation	rs142176273	T2872M	0.21
STAD	chr1	197102395	Frame_Shift_Ins	novel	*K2286Sfs7**	0.16
STAD	chr1	197100546	Missense_Mutation	NA	Q2902R	0.66
STAD	chr1	197104102	Frame_Shift_Del	rs199422167	I1717*	0.25
STAD	chr1	197104966	Missense_Mutation	NA	S1429P	0.21
STAD	chr1	197124307	Nonsense_Mutation	NA	Q1065*	0.35
STAD	chr1	197090030	Missense_Mutation	novel	A3295G	0.33
STAD	chr1	197103990	Missense_Mutation	rs759380732	A1754V	0.07
STAD	chr1	197103061	Missense_Mutation	novel	A2064T	0.05
STAD	chr1	197132309	Silent	NA	P821P	0.47
STAD	chr1	197146304	Missense_Mutation	NA	C45Y	0.12
STAD	chr1	197142583	Missense_Mutation	NA	S557C	0.09
STAD	chr1	197125072	Missense_Mutation	rs780791970	R1019Q	0.14
STAD	chr1	197105100	Frame_Shift_Ins	novel	*I1384Nfs8**	0.23
STAD	chr1	197104052	Missense_Mutation	novel	I1733M	0.11
STAD	chr1	197101653	Missense_Mutation	NA	S2533C	0.3
STAD	chr1	197128601	Missense_Mutation	rs760611432	R942H	0.17
STAD	chr1	197100980	Frame_Shift_Del	novel	*K2757Nfs2**	0.1
STAD	chr1	197101942	Frame_Shift_Ins	novel	*V2437Cfs14**	0.33
STAD	chr1	197103896	Silent	NA	Y1785Y	0.05
STAD	chr1	197122581	Frame_Shift_Del	novel	*T1135Sfs24**	0.21
STAD	chr1	197101097	Missense_Mutation	rs150872657	I2718M	0.24
STAD	chr1	197101187	Missense_Mutation	novel	M2688I	0.32
STAD	chr1	197101631	Silent	rs147160053	A2540A	0.3
STAD	chr1	197128667	Splice_Site	novel	X921_splice	0.67
TGCT	chr1	197146190	Missense_Mutation	novel	P83Q	0.2
THCA	chr1	197121971	Frame_Shift_Ins	novel	*L1272Ifs16**	0.16
THCA	chr1	197090907	Silent	NA	R3193R	0.16
THCA	chr1	197143601	In_Frame_Ins	novel	N217_K218insSFLI	0.05
UCEC	chr1	197100732	Missense_Mutation	NA	A2840D	0.16
UCEC	chr1	197090380	Nonsense_Mutation	NA	W3215*	0.4
UCEC	chr1	197096032	Missense_Mutation	NA	Q2985K	0.32
UCEC	chr1	197102088	Frame_Shift_Ins	novel	*A2388Vfs6**	0.05
UCEC	chr1	197142407	Missense_Mutation	NA	K615N	0.29
UCEC	chr1	197084386	Nonsense_Mutation	novel	E3458*	0.06
UCEC	chr1	197102166	Missense_Mutation	NA	V2362A	0.27
UCEC	chr1	197133347	Splice_Region	rs763738706		0.34
UCEC	chr1	197090944	Missense_Mutation	novel	R3181Q	0.21
UCEC	chr1	197093088	Silent	novel	L3086L	0.26
UCEC	chr1	197104519	Nonsense_Mutation	NA	R1578*	0.28
UCEC	chr1	197104756	Missense_Mutation	rs756067585	R1499W	0.11
UCEC	chr1	197105082	Missense_Mutation	novel	Y1390C	0.08
UCEC	chr1	197117856	Missense_Mutation	novel	R1333I	0.41
UCEC	chr1	197133392	Missense_Mutation	rs779018406	R793W	0.26
UCEC	chr1	197142948	Missense_Mutation	rs150684410	S435L	0.33
UCEC	chr1	197104756	Missense_Mutation	rs756067585	R1499W	0.35
UCEC	chr1	197096010	Missense_Mutation	novel	L2992P	0.23
UCEC	chr1	197100886	Missense_Mutation	novel	S2789R	0.52
UCEC	chr1	197101636	Missense_Mutation	novel	A2539T	0.42
UCEC	chr1	197128487	Splice_Region	novel		0.44
UCEC	chr1	197143643	Silent	rs587783255	G203G	0.5
UCEC	chr1	197093241	Silent	novel	L3035L	0.15
UCEC	chr1	197122485	Missense_Mutation	novel	Q1167H	0.73
UCEC	chr1	197144093	Missense_Mutation	novel	E102V	0.69
UCEC	chr1	197100859	Missense_Mutation	NA	Y2798H	0.45
UCEC	chr1	197104220	Silent	NA	S1677S	0.23
UCEC	chr1	197101707	Missense_Mutation	rs751584273	R2515Q	0.32
UCEC	chr1	197103156	Missense_Mutation	rs149033840	R2032H	0.38
UCEC	chr1	197103019	Nonsense_Mutation	rs199422168	R2078*	0.26
UCEC	chr1	197133493	Missense_Mutation	rs375901171	R759Q	0.36
UCEC	chr1	197143722	Missense_Mutation	novel	K177T	0.56
UCEC	chr1	197084198	3'UTR	novel		0.35
UCEC	chr1	197091909	Nonsense_Mutation	novel	Q3148*	0.35
UCEC	chr1	197103671	Silent	rs149111545	A1860A	0.41
UCEC	chr1	197121967	Missense_Mutation	novel	I1273T	0.46
UCEC	chr1	197124883	Missense_Mutation	rs550484483	A1052V	0.43
UCEC	chr1	197103258	Missense_Mutation	novel	L1998R	0.1
UCEC	chr1	197104756	Missense_Mutation	rs756067585	R1499W	0.27
UCEC	chr1	197142506	Missense_Mutation	novel	E582D	0.24
UCEC	chr1	197143495	Missense_Mutation	novel	S253P	0.35
UCEC	chr1	197117875	Nonsense_Mutation	NA	R1327*	0.26
UCEC	chr1	197125123	Missense_Mutation	rs749600804	R1002H	0.18
UCEC	chr1	197086842	Missense_Mutation	NA	F3431C	0.31
UCEC	chr1	197102946	Missense_Mutation	NA	S2102Y	0.25
UCEC	chr1	197103949	Missense_Mutation	rs770335356	R1768W	0.22
UCEC	chr1	197086860	Missense_Mutation	NA	S3425F	0.09
UCEC	chr1	197089974	Missense_Mutation	NA	E3314K	0.14
UCEC	chr1	197103016	Missense_Mutation	NA	G2079C	0.23
UCEC	chr1	197103440	Silent	NA	G1937G	0.13
UCEC	chr1	197124303	Nonsense_Mutation	NA	L1066*	0.26
UCEC	chr1	197129941	Missense_Mutation	NA	P868H	0.24
UCEC	chr1	197102168	Silent	rs755647301	S2361S	0.18
UCEC	chr1	197102757	Missense_Mutation	novel	T2165I	0.36
UCEC	chr1	197092032	Nonsense_Mutation	rs199422187	R3107*	0.31
UCEC	chr1	197102088	Frame_Shift_Ins	novel	*A2388Vfs6**	0.15
UCEC	chr1	197142942	Missense_Mutation	rs551198579	R437H	0.1
UCEC	chr1	197143524	Missense_Mutation	rs201143810	R243Q	0.11
UCEC	chr1	197102241	Missense_Mutation	NA	A2337V	0.29
UCEC	chr1	197086808	Silent	novel	V3442V	0.2
UCEC	chr1	197090229	Missense_Mutation	novel	L3266I	0.16
UCEC	chr1	197100693	Missense_Mutation	rs148245202	R2853Q	0.18
UCEC	chr1	197129983	Missense_Mutation	novel	R854H	0.18
UCEC	chr1	197143226	Missense_Mutation	novel	M342I	0.22
UCEC	chr1	197090004	Nonsense_Mutation	rs587783295	R3304*	0.22
UCEC	chr1	197086860	Missense_Mutation	novel	S3425Y	0.53
UCEC	chr1	197102400	Missense_Mutation	rs371321801	S2284F	0.32
UCEC	chr1	197102064	Missense_Mutation	NA	R2396M	0.39
UCEC	chr1	197102928	Missense_Mutation	NA	R2108K	0.13
UCEC	chr1	197104354	Missense_Mutation	rs200202166	R1633C	0.12
UCEC	chr1	197117858	Silent	NA	Q1332Q	0.32
UCEC	chr1	197142415	Missense_Mutation	NA	A613T	0.26
UCEC	chr1	197143524	Missense_Mutation	rs201143810	R243Q	0.34
UCEC	chr1	197142520	Missense_Mutation	rs60950503	D578N	0.46
UCEC	chr1	197125118	Nonsense_Mutation	NA	Q1004*	0.22
UCEC	chr1	197143000	Missense_Mutation	NA	E418K	0.16
UCEC	chr1	197103660	Frame_Shift_Ins	novel	*L1864Qfs5**	0.1
UCEC	chr1	197122593	Frame_Shift_Ins	novel	*E1132Cfs32**	0.05
UCEC	chr1	197105115	Missense_Mutation	NA	S1379F	0.21
UCEC	chr1	197102986	Nonsense_Mutation	novel	E2089*	0.14
UCEC	chr1	197143527	Missense_Mutation	rs374323328	R242H	0.25
UCEC	chr1	197086865	Missense_Mutation	novel	K3423N	0.27
UCEC	chr1	197090270	Missense_Mutation	novel	R3252I	0.33
UCEC	chr1	197101293	Missense_Mutation	novel	S2653F	0.44
UCEC	chr1	197102853	Missense_Mutation	novel	R2133I	0.48
UCEC	chr1	197139813	Silent	rs151087446	I660I	0.34
UCEC	chr1	197090270	Missense_Mutation	novel	R3252I	0.46
UCEC	chr1	197101475	Silent	novel	K2592K	0.19
UCEC	chr1	197102565	Missense_Mutation	novel	R2229I	0.46
UCEC	chr1	197128656	Nonsense_Mutation	novel	E924*	0.46
UCEC	chr1	197129195	Missense_Mutation	rs142655430	E918K	0.55
UCEC	chr1	197143143	Missense_Mutation	novel	S370Y	0.43
UCEC	chr1	197088350	Missense_Mutation	novel	K3356R	0.07
UCEC	chr1	197101650	Missense_Mutation	novel	A2534V	0.14
UCEC	chr1	197103323	Silent	novel	I1976I	0.24
UCEC	chr1	197104593	Missense_Mutation	novel	A1553V	0.18
UCEC	chr1	197124883	Missense_Mutation	rs550484483	A1052V	0.18
UCEC	chr1	197125133	Missense_Mutation	novel	A999T	0.11
UCEC	chr1	197143979	Missense_Mutation	novel	A140V	0.21
UCEC	chr1	197101905	Missense_Mutation	rs373426629	H2449R	0.27
UCEC	chr1	197090328	Nonsense_Mutation	rs199422194	R3233*	0.34
UCEC	chr1	197093102	Frame_Shift_Ins	rs749449214	*S3082Ifs42**	0.33
UCEC	chr1	197101950	Missense_Mutation	novel	T2434I	0.42
UCEC	chr1	197103288	Missense_Mutation	novel	K1988M	0.26
UCEC	chr1	197103429	Missense_Mutation	novel	C1941Y	0.49
UCEC	chr1	197103782	Missense_Mutation	novel	Q1823H	0.46
UCEC	chr1	197104387	Frame_Shift_Ins	novel	*A1622Cfs23**	0.6
UCEC	chr1	197104824	Missense_Mutation	novel	R1476K	0.44
UCEC	chr1	197105076	Missense_Mutation	rs765050426	R1392Q	0.34
UCEC	chr1	197129303	Missense_Mutation	novel	L882V	0.36
UCEC	chr1	197103683	Silent	NA	R1856R	0.28
UCEC	chr1	197091037	Missense_Mutation	NA	W3150L	0.41
UCEC	chr1	197143277	Silent	NA	S325S	0.33
UCEC	chr1	197124169	Nonsense_Mutation	novel	E1111*	0.1
UCEC	chr1	197143448	Missense_Mutation	novel	K268N	0.33
UCEC	chr1	197084127	3'Flank	novel		0.57
UCEC	chr1	197096145	Missense_Mutation	novel	R2947K	0.57
UCEC	chr1	197101207	Nonsense_Mutation	novel	R2682*	0.32
UCEC	chr1	197102455	Missense_Mutation	rs200800956	A2266T	0.53
UCEC	chr1	197104333	Nonsense_Mutation	novel	Q1640*	0.39
UCEC	chr1	197104940	Silent	novel	R1437R	0.34
UCEC	chr1	197130024	Silent	novel	D840D	0.39
UCEC	chr1	197139852	Silent	novel	T647T	0.07
UCEC	chr1	197088427	Silent	novel	E3330E	0.52
UCEC	chr1	197101581	Missense_Mutation	novel	S2557Y	0.58
UCEC	chr1	197092032	Nonsense_Mutation	rs199422187	R3107*	0.36
UCEC	chr1	197103636	Frame_Shift_Del	NA	L1872*	0.36
UCEC	chr1	197093089	Missense_Mutation	novel	L3086P	0.08
UCEC	chr1	197104280	Silent	rs369031263	T1657T	0.2
UCEC	chr1	197101118	Missense_Mutation	novel	K2711N	0.5
UCEC	chr1	197139811	Missense_Mutation	novel	A661V	0.09
UCEC	chr1	197084257	3'UTR	novel		0.24
UCEC	chr1	197139770	Frame_Shift_Del	novel	*T675Qfs33**	0.46
UCEC	chr1	197102656	Missense_Mutation	novel	N2199H	0.4
UCEC	chr1	197103019	Nonsense_Mutation	rs199422168	R2078*	0.17
UCEC	chr1	197104065	Missense_Mutation	rs768999000	R1729Q	0.5
UCEC	chr1	197117960	Missense_Mutation	novel	I1298M	0.61
UCEC	chr1	197142837	Missense_Mutation	novel	F472C	0.44
UCEC	chr1	197086964	Silent	NA	R3390R	0.25
UCEC	chr1	197122471	Missense_Mutation	rs201067420	T1172M	0.3
UCEC	chr1	197090003	Missense_Mutation	rs149859034	R3304Q	0.29
UCEC	chr1	197091021	Silent	novel	L3155L	0.07
UCEC	chr1	197100581	Missense_Mutation	novel	Q2890H	0.27
UCEC	chr1	197100690	Missense_Mutation	novel	R2854I	0.13
UCEC	chr1	197103019	Nonsense_Mutation	rs199422168	R2078*	0.41
UCEC	chr1	197103732	Missense_Mutation	novel	K1840T	0.29
UCEC	chr1	197103922	Missense_Mutation	novel	A1777T	0.19
UCEC	chr1	197121973	Missense_Mutation	rs762167214	R1271Q	0.2
UCEC	chr1	197129195	Missense_Mutation	rs142655430	E918K	0.18
UCEC	chr1	197132298	Missense_Mutation	rs766198125	R825Q	0.22
UCEC	chr1	197133379	Missense_Mutation	rs750028073	R797Q	0.35
UCEC	chr1	197139844	Missense_Mutation	NA	S650Y	0.44
UCEC	chr1	197144038	Silent	novel	E120E	0.3
UCEC	chr1	197143201	Missense_Mutation	rs200881457	V351M	0.41
UCEC	chr1	197090909	Missense_Mutation	rs140679756	R3193C	0.3
UCEC	chr1	197093238	Silent	rs770908469	I3036I	0.25
UCEC	chr1	197146204	Silent	NA	K78K	0.12
UCEC	chr1	197090944	Missense_Mutation	novel	R3181Q	0.3
UCEC	chr1	197101889	Missense_Mutation	novel	F2454L	0.29
UCEC	chr1	197103949	Missense_Mutation	rs770335356	R1768W	0.4
UCEC	chr1	197104408	Missense_Mutation	novel	H1615N	0.36
UCEC	chr1	197104870	Missense_Mutation	novel	Q1461E	0.36
UCEC	chr1	197117956	Missense_Mutation	novel	Q1300K	0.28
UCEC	chr1	197122425	Missense_Mutation	novel	D1187E	0.16
UCEC	chr1	197092055	Missense_Mutation	novel	F3099C	0.41
UCEC	chr1	197093254	Missense_Mutation	rs775344657	R3031Q	0.36
UCEC	chr1	197101023	Missense_Mutation	rs202193200	R2743Q	0.29
UCEC	chr1	197103019	Nonsense_Mutation	rs199422168	R2078*	0.33
UCEC	chr1	197129258	Missense_Mutation	novel	L897I	0.28
UCEC	chr1	197084237	3'UTR	novel		0.24
UCEC	chr1	197089992	Missense_Mutation	rs772982246	R3308C	0.43
UCEC	chr1	197090217	Missense_Mutation	novel	L3270I	0.46
UCEC	chr1	197101258	Missense_Mutation	rs201881549	R2665C	0.45
UCEC	chr1	197128654	Missense_Mutation	novel	E924D	0.55
UCEC	chr1	197133473	Missense_Mutation	NA	R766C	0.56
UCEC	chr1	197142631	Missense_Mutation	novel	F541V	0.45
UCEC	chr1	197143404	Missense_Mutation	novel	S283Y	0.53
UCEC	chr1	197144094	Nonsense_Mutation	NA	E102*	0.29
UCEC	chr1	197101261	Missense_Mutation	novel	V2664L	0.4
UCEC	chr1	197088322	Silent	NA	G3365G	0.35
UCEC	chr1	197102326	Missense_Mutation	NA	L2309F	0.27
UCEC	chr1	197104131	Missense_Mutation	novel	F1707C	0.5
UCEC	chr1	197093195	Missense_Mutation	rs142024644	R3051W	0.34
UCEC	chr1	197102868	Missense_Mutation	NA	K2128I	0.24
UCEC	chr1	197104519	Nonsense_Mutation	NA	R1578*	0.29
UCEC	chr1	197104756	Missense_Mutation	rs756067585	R1499W	0.27
UCEC	chr1	197104758	Missense_Mutation	novel	F1498C	0.08
UCEC	chr1	197105115	Missense_Mutation	NA	S1379Y	0.17
UCEC	chr1	197117916	Missense_Mutation	NA	R1313I	0.16
UCEC	chr1	197101151	Silent	novel	R2700R	0.16
UCEC	chr1	197121956	Missense_Mutation	novel	W1277G	0.21
UCEC	chr1	197124882	Silent	rs143680877	A1052A	0.09
UCEC	chr1	197142338	Missense_Mutation	novel	K638N	0.11
UCEC	chr1	197142647	Missense_Mutation	novel	Q535H	0.09
UCEC	chr1	197143160	Missense_Mutation	novel	K364N	0.16
UCEC	chr1	197093234	Missense_Mutation	novel	A3038S	0.24
UCEC	chr1	197100632	Nonsense_Mutation	novel	W2873*	0.44
UCEC	chr1	197102172	Missense_Mutation	novel	A2360V	0.21
UCEC	chr1	197102951	Silent	novel	I2100I	0.26
UCEC	chr1	197105037	Missense_Mutation	rs143092798	R1405H	0.25
UCEC	chr1	197122514	Missense_Mutation	novel	F1158I	0.21
UCEC	chr1	197139794	Silent	novel	L667L	0.33
UCEC	chr1	197143404	Missense_Mutation	rs199422128	S283F	0.24
UCEC	chr1	197104852	Missense_Mutation	novel	S1467P	0.11
UCEC	chr1	197102811	Missense_Mutation	novel	Q2147R	0.33
UCEC	chr1	197143554	Missense_Mutation	rs758801375	G233D	0.13
UCEC	chr1	197084342	Silent	rs150108952	T3472T	0.07
UCEC	chr1	197089991	Missense_Mutation	rs201362977	R3308H	0.17
UCEC	chr1	197100830	Missense_Mutation	novel	Q2807H	0.05
UCEC	chr1	197101619	Missense_Mutation	NA	M2544I	0.18
UCEC	chr1	197101995	Missense_Mutation	novel	R2419I	0.05
UCEC	chr1	197103947	Silent	rs770431814	R1768R	0.17
UCEC	chr1	197103948	Missense_Mutation	rs781557550	R1768Q	0.07
UCEC	chr1	197142784	Missense_Mutation	rs779965746	R490C	0.18
UCEC	chr1	197144094	Nonsense_Mutation	NA	E102*	0.12
UCEC	chr1	197104353	Missense_Mutation	rs181624297	R1633H	0.43
UCEC	chr1	197101734	Missense_Mutation	novel	A2506D	0.37
UCEC	chr1	197135221	Missense_Mutation	novel	P683Q	0.08
UCEC	chr1	197084205	3'UTR	novel		0.32
UCEC	chr1	197102632	Missense_Mutation	novel	T2207P	0.19
UCEC	chr1	197102089	Missense_Mutation	novel	A2388S	0.18
UCEC	chr1	197091025	Missense_Mutation	NA	R3154I	0.46
UCEC	chr1	197091983	Missense_Mutation	NA	R3123I	0.42
UCEC	chr1	197100784	Missense_Mutation	NA	K2823Q	0.5
UCEC	chr1	197103648	Missense_Mutation	rs761106315	R1868I	0.37
UCEC	chr1	197129195	Missense_Mutation	rs142655430	E918K	0.42
UCEC	chr1	197130044	Missense_Mutation	NA	E834K	0.43
UCEC	chr1	197132298	Missense_Mutation	rs766198125	R825Q	0.55
UCEC	chr1	197135171	Missense_Mutation	NA	E700K	0.55
UCEC	chr1	197139824	Missense_Mutation	NA	K657Q	0.47
UCEC	chr1	197101152	Missense_Mutation	rs757182094	R2700Q	0.82
UCEC	chr1	197091032	Nonsense_Mutation	rs587783292	R3152*	0.31
UCEC	chr1	197104747	Missense_Mutation	NA	Q1502K	0.14
UCEC	chr1	197100830	Missense_Mutation	novel	Q2807H	0.42
UCEC	chr1	197088235	Intron	novel		0.35
UCEC	chr1	197102777	Missense_Mutation	novel	M2158I	0.28
UCEC	chr1	197104212	Frame_Shift_Del	novel	*N1680Mfs4**	0.25
UCEC	chr1	197088305	Missense_Mutation	NA	K3371T	0.35
UCEC	chr1	197100687	Missense_Mutation	novel	R2855K	0.43
UCEC	chr1	197100915	Missense_Mutation	NA	R2779I	0.23
UCEC	chr1	197102468	In_Frame_Ins	novel	M2261delinsIDW	0.09
UCEC	chr1	197103208	Missense_Mutation	NA	H2015N	0.32
UCEC	chr1	197103648	Missense_Mutation	rs761106315	R1868I	0.42
UCEC	chr1	197104324	Missense_Mutation	novel	Y1643N	0.15
UCEC	chr1	197142886	Nonsense_Mutation	rs199422141	E456*	0.36
UCEC	chr1	197086860	Missense_Mutation	novel	S3425Y	0.3
UCEC	chr1	197102569	Nonsense_Mutation	novel	E2228*	0.32
UCEC	chr1	197104855	Missense_Mutation	novel	N1466H	0.27
UCEC	chr1	197084423	Splice_Site	novel	X3444_splice	0.13
UCEC	chr1	197102088	Nonsense_Mutation	novel	*A2388Efs3**	0.08
UCEC	chr1	197103634	Nonsense_Mutation	novel	*L1872_K1873insLHMHSIVLYDTRTHFL**	0.07
UCEC	chr1	197096068	Nonsense_Mutation	NA	E2973*	0.26
UCEC	chr1	197143983	Missense_Mutation	NA	N139H	0.23
UCEC	chr1	197101183	Missense_Mutation	rs41302133	R2690W	0.53
UCEC	chr1	197101344	Missense_Mutation	novel	K2636R	0.19
UCEC	chr1	197102038	Missense_Mutation	novel	K2405Q	0.16
UCEC	chr1	197102700	Missense_Mutation	rs200848981	R2184Q	0.36
UCEC	chr1	197103410	Silent	novel	L1947L	0.28
UCEC	chr1	197103867	Missense_Mutation	novel	R1795M	0.46
UCEC	chr1	197105106	Missense_Mutation	novel	R1382I	0.24
UCEC	chr1	197124148	Missense_Mutation	novel	D1118N	0.11
UCEC	chr1	197129271	Silent	novel	L892L	0.25
UCEC	chr1	197132299	Nonsense_Mutation	rs753550302	R825*	0.46
UCEC	chr1	197143225	Missense_Mutation	NA	F343L	0.15
UCEC	chr1	197143786	Missense_Mutation	novel	K156Q	0.35
UCEC	chr1	197144012	Missense_Mutation	novel	V129A	0.15
UCEC	chr1	197086860	Missense_Mutation	novel	S3425Y	0.12
UCEC	chr1	197104000	Nonsense_Mutation	novel	Q1751*	0.26
UCEC	chr1	197122446	Silent	NA	N1180N	0.13
UCEC	chr1	197090048	Missense_Mutation	novel	N3289T	0.09
UCEC	chr1	197090387	Missense_Mutation	NA	A3213V	0.19
UCEC	chr1	197090945	Nonsense_Mutation	rs754689827	R3181*	0.22
UCEC	chr1	197091996	Missense_Mutation	NA	L3119M	0.17
UCEC	chr1	197103951	Missense_Mutation	novel	A1767D	0.04
UCEC	chr1	197124142	Missense_Mutation	novel	V1120I	0.05
UCEC	chr1	197124909	Missense_Mutation	novel	K1043N	0.04
UCEC	chr1	197143626	Missense_Mutation	NA	N209T	0.18
UCEC	chr1	197101602	Frame_Shift_Del	novel	L2550*	0.35
UCEC	chr1	197088239	Intron	novel		0.13
UCEC	chr1	197086865	Missense_Mutation	novel	K3423N	0.46
UCEC	chr1	197101221	Missense_Mutation	novel	R2677K	0.31
UCEC	chr1	197101522	Missense_Mutation	novel	Q2577K	0.38
UCEC	chr1	197124200	Missense_Mutation	novel	K1100N	0.41
UCEC	chr1	197142753	Missense_Mutation	novel	R500K	0.36
UCEC	chr1	197143172	Missense_Mutation	novel	E360D	0.49
UCEC	chr1	197143524	Missense_Mutation	rs201143810	R243Q	0.57
UCEC	chr1	197086860	Missense_Mutation	novel	S3425Y	0.33
UCEC	chr1	197103288	Missense_Mutation	novel	K1988T	0.31
UCEC	chr1	197103665	Missense_Mutation	novel	K1862N	0.5
UCEC	chr1	197132347	Missense_Mutation	rs751289232	R809C	0.3
UCEC	chr1	197143112	Missense_Mutation	novel	Q380H	0.19
UCS	chr1	197090995	Missense_Mutation	novel	Y3164F	0.13
UCS	chr1	197104756	Missense_Mutation	rs756067585	R1499W	0.32
UCS	chr1	197129984	Missense_Mutation	rs771828613	R854C	0.36
UCS	chr1	197142554	Silent	rs372072744	S566S	0.28
UCS	chr1	197102256	Missense_Mutation	novel	R2332L	0.47
UVM	chr1	197142406	Missense_Mutation	novel	K616Q	0.53
UVM	chr1	197142407	Silent	novel	K615K	0.52

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	DEL	0.0809	0.033566
DLBC	DEL	0.0417	0.0017831
KIRC	AMP	0.0852	0.059566
PAAD	AMP	0.212	0.085665
READ	AMP	0.2667	0.14328
TGCT	AMP	0.3467	0.088103
THCA	AMP	0.0481	0.075436

Survival Analysis

Cancer	P-value	Q-value
THYM	0.0035	Kaplan-Meier Survival Analysis
KIRC	0.0001	Kaplan-Meier Survival Analysis
SARC	0.012	Kaplan-Meier Survival Analysis
MESO	0.00015	Kaplan-Meier Survival Analysis
UCS	0.0095	Kaplan-Meier Survival Analysis
LUSC	0.038	Kaplan-Meier Survival Analysis
KIRP	0.00013	Kaplan-Meier Survival Analysis
PAAD	0.00014	Kaplan-Meier Survival Analysis
PCPG	0.024	Kaplan-Meier Survival Analysis
KICH	0.0053	Kaplan-Meier Survival Analysis
UCEC	0.00031	Kaplan-Meier Survival Analysis
LIHC	0.00015	Kaplan-Meier Survival Analysis
CHOL	0.021	Kaplan-Meier Survival Analysis
LUAD	0.0001	Kaplan-Meier Survival Analysis
UVM	0.032	Kaplan-Meier Survival Analysis
OV	0.038	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742