EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000066651 (Gene tree)
Gene ID: 60487
Gene Symbol: TRMT11
Alias: MDS024|dJ187J11.2|TRM11|TRMT11-1|C6orf75
Full Name: tRNA methyltransferase 11 homolog
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 217,388 bases
Position: chr6:125,986,430-126,203,817
Accession: 21080
RBP type: canonical RBP
Summary: (TRNA Methyltransferase 11 Homolog) is a Protein Coding gene. Among its related pathways are Gene Expression and tRNA processing. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and N-methyltransferase activity.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000333934	UPF0020	PF01170.18	5e-11	1	1
ENSP00000357316	UPF0020	PF01170.18	5.1e-11	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000479748	TRMT11-210	2093	-	ENSP00000433724	257 (aa)	-	Q7Z4G4
ENST00000368332	TRMT11-202	1889	-	ENSP00000357316	458 (aa)	-	Q7Z4G4
ENST00000444121	TRMT11-203	617	-	ENSP00000406230	93 (aa)	-	Q5JY01
ENST00000461129	TRMT11-206	758	-	ENSP00000467603	82 (aa)	-	K7EPZ4
ENST00000473273	TRMT11-209	258	-	ENSP00000465275	86 (aa)	-	K7EJQ4
ENST00000334379	TRMT11-201	1565	XM_017011168	ENSP00000333934	463 (aa)	XP_016866657	Q7Z4G4
ENST00000466316	TRMT11-207	729	-	ENSP00000466001	4 (aa)	-	V9GXZ6
ENST00000468097	TRMT11-208	1009	-	ENSP00000467035	230 (aa)	-	K7ENP1
ENST00000648977	TRMT11-212	4437	-	ENSP00000496820	230 (aa)	-	UPI00028408AD
ENST00000489934	TRMT11-211	418	-	-	- (aa)	-	-
ENST00000446681	TRMT11-205	657	-	ENSP00000415724	134 (aa)	-	Q5JY02
ENST00000444229	TRMT11-204	583	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000066651's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000066651	Apolipoproteins B	6.17556487216985E-5	17903299
ENSG00000066651	Apolipoproteins B	6.57952803608122E-5	17903299
ENSG00000066651	Vitamin K	1.18509847636992E-7	17903293
ENSG00000066651	Vitamin K	5.79359220573588E-7	17903293

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000066651	rs141259875	6	126066472	?	Psychosis proneness (hypomanic personality scale and revised physical anhedonia scale)	28525603			EFO_0008337
ENSG00000066651	rs1455740	6	126184256	G	Behavioural changes in frontotemporal lobe dementia	29724592	[1.25-50]	2.4390244	Orphanet_282\|GO_0007610
ENSG00000066651	rs1268119	6	126054435	?	Heel bone mineral density	30048462	[0.012-0.021] unit decrease	0.0161574	EFO_0009270
ENSG00000066651	rs4363059	6	126145459	T	Male-pattern baldness	28196072	NR unit increase	0.0386951	Orphanet_79364
ENSG00000066651	rs1268119	6	126054435	T	Heel bone mineral density	30598549	[0.011-0.019] unit decrease	0.0151304	EFO_0009270
ENSG00000066651	rs4363059	6	126145459	?	Balding type 1	30595370			EFO_0007825
ENSG00000066651	rs9491565	6	126138319	G	Male-pattern baldness	30573740	[0.025-0.038] unit increase	0.0317518	EFO_0007825
ENSG00000066651	rs6920788	6	126010842	?	Waist-hip ratio	30595370			EFO_0004343
ENSG00000066651	rs2326201	6	126065257	?	Heel bone mineral density	30595370			EFO_0009270
ENSG00000066651	rs993744	6	126175943	?	Heel bone mineral density	30595370			EFO_0009270

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000066651's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000066651	TRMT11	100	67.910	ENSAPOG00000010741	trmt11	97	67.841	Acanthochromis_polyacanthus
ENSG00000066651	TRMT11	100	97.761	ENSAMEG00000009509	TRMT11	99	96.112	Ailuropoda_melanoleuca
ENSG00000066651	TRMT11	100	67.910	ENSACIG00000020205	trmt11	91	69.544	Amphilophus_citrinellus
ENSG00000066651	TRMT11	100	67.910	ENSAOCG00000020121	trmt11	97	67.834	Amphiprion_ocellaris
ENSG00000066651	TRMT11	100	67.910	ENSAPEG00000017412	trmt11	97	67.834	Amphiprion_percula
ENSG00000066651	TRMT11	100	70.896	ENSATEG00000024365	trmt11	96	70.222	Anabas_testudineus
ENSG00000066651	TRMT11	100	79.570	ENSAPLG00000002183	TRMT11	97	74.393	Anas_platyrhynchos
ENSG00000066651	TRMT11	100	79.851	ENSACAG00000002072	TRMT11	96	75.604	Anolis_carolinensis
ENSG00000066651	TRMT11	100	99.254	ENSANAG00000033565	TRMT11	100	96.976	Aotus_nancymaae
ENSG00000066651	TRMT11	100	70.149	ENSACLG00000019724	trmt11	97	68.212	Astatotilapia_calliptera
ENSG00000066651	TRMT11	100	68.657	ENSAMXG00000020379	trmt11	99	67.452	Astyanax_mexicanus
ENSG00000066651	TRMT11	100	96.269	ENSBTAG00000001957	TRMT11	99	94.537	Bos_taurus
ENSG00000066651	TRMT11	96	32.530	WBGene00022107	Y71F9AL.1	93	36.077	Caenorhabditis_elegans
ENSG00000066651	TRMT11	100	98.507	ENSCJAG00000003686	TRMT11	100	96.437	Callithrix_jacchus
ENSG00000066651	TRMT11	100	97.761	ENSCAFG00000001057	TRMT11	99	96.183	Canis_familiaris
ENSG00000066651	TRMT11	100	97.761	ENSCAFG00020021931	TRMT11	100	95.680	Canis_lupus_dingo
ENSG00000066651	TRMT11	100	95.522	ENSCHIG00000020274	TRMT11	100	94.600	Capra_hircus
ENSG00000066651	TRMT11	96	91.406	ENSTSYG00000004430	TRMT11	100	86.609	Carlito_syrichta
ENSG00000066651	TRMT11	100	88.060	ENSCAPG00000013532	TRMT11	96	85.779	Cavia_aperea
ENSG00000066651	TRMT11	100	90.929	ENSCPOG00000009124	TRMT11	100	90.929	Cavia_porcellus
ENSG00000066651	TRMT11	100	100.000	ENSCCAG00000018903	TRMT11	100	97.192	Cebus_capucinus
ENSG00000066651	TRMT11	100	100.000	ENSCATG00000039002	TRMT11	100	97.624	Cercocebus_atys
ENSG00000066651	TRMT11	100	92.009	ENSCLAG00000015746	TRMT11	100	92.009	Chinchilla_lanigera
ENSG00000066651	TRMT11	100	98.925	ENSCSAG00000016335	TRMT11	100	97.408	Chlorocebus_sabaeus
ENSG00000066651	TRMT11	100	84.946	ENSCPBG00000018528	TRMT11	95	79.956	Chrysemys_picta_bellii
ENSG00000066651	TRMT11	100	43.165	ENSCING00000017363	-	98	45.987	Ciona_intestinalis
ENSG00000066651	TRMT11	100	100.000	ENSCANG00000036944	TRMT11	100	96.112	Colobus_angolensis_palliatus
ENSG00000066651	TRMT11	100	95.699	ENSCGRG00001017153	Trmt11	100	92.441	Cricetulus_griseus_chok1gshd
ENSG00000066651	TRMT11	100	95.699	ENSCGRG00000008525	Trmt11	97	92.938	Cricetulus_griseus_crigri
ENSG00000066651	TRMT11	100	69.403	ENSCSEG00000009069	trmt11	98	67.457	Cynoglossus_semilaevis
ENSG00000066651	TRMT11	100	67.910	ENSCVAG00000020822	trmt11	96	67.778	Cyprinodon_variegatus
ENSG00000066651	TRMT11	100	70.149	ENSDARG00000040033	trmt11	99	69.110	Danio_rerio
ENSG00000066651	TRMT11	100	92.657	ENSDNOG00000002737	TRMT11	100	92.657	Dasypus_novemcinctus
ENSG00000066651	TRMT11	100	95.522	ENSDORG00000011192	Trmt11	100	93.089	Dipodomys_ordii
ENSG00000066651	TRMT11	98	40.998	FBgn0037250	CG1074	93	40.998	Drosophila_melanogaster
ENSG00000066651	TRMT11	100	87.313	ENSETEG00000007352	-	71	90.361	Echinops_telfairi
ENSG00000066651	TRMT11	99	57.918	ENSEBUG00000014368	trmt11	95	57.918	Eptatretus_burgeri
ENSG00000066651	TRMT11	100	93.284	ENSEASG00005009411	TRMT11	100	92.441	Equus_asinus_asinus
ENSG00000066651	TRMT11	100	93.284	ENSECAG00000017788	TRMT11	100	92.689	Equus_caballus
ENSG00000066651	TRMT11	90	89.189	ENSEEUG00000002249	-	74	91.026	Erinaceus_europaeus
ENSG00000066651	TRMT11	100	70.149	ENSELUG00000005252	trmt11	91	66.953	Esox_lucius
ENSG00000066651	TRMT11	100	95.522	ENSFCAG00000027670	TRMT11	100	95.248	Felis_catus
ENSG00000066651	TRMT11	100	79.104	ENSFALG00000011486	TRMT11	100	76.078	Ficedula_albicollis
ENSG00000066651	TRMT11	100	94.030	ENSFDAG00000006745	TRMT11	100	92.657	Fukomys_damarensis
ENSG00000066651	TRMT11	100	67.164	ENSFHEG00000003504	trmt11	97	61.830	Fundulus_heteroclitus
ENSG00000066651	TRMT11	100	65.672	ENSGMOG00000006618	trmt11	96	66.075	Gadus_morhua
ENSG00000066651	TRMT11	100	78.358	ENSGALG00000014831	TRMT11	99	76.623	Gallus_gallus
ENSG00000066651	TRMT11	100	67.910	ENSGAFG00000000144	trmt11	96	67.952	Gambusia_affinis
ENSG00000066651	TRMT11	100	70.149	ENSGACG00000006060	trmt11	98	67.028	Gasterosteus_aculeatus
ENSG00000066651	TRMT11	100	79.570	ENSGAGG00000005813	TRMT11	96	78.556	Gopherus_agassizii
ENSG00000066651	TRMT11	100	100.000	ENSGGOG00000017016	TRMT11	100	99.568	Gorilla_gorilla
ENSG00000066651	TRMT11	100	70.149	ENSHBUG00000012185	trmt11	97	68.212	Haplochromis_burtoni
ENSG00000066651	TRMT11	100	93.284	ENSHGLG00000014007	TRMT11	100	93.089	Heterocephalus_glaber_female
ENSG00000066651	TRMT11	100	93.284	ENSHGLG00100007509	TRMT11	100	93.089	Heterocephalus_glaber_male
ENSG00000066651	TRMT11	98	70.229	ENSHCOG00000019331	trmt11	92	65.044	Hippocampus_comes
ENSG00000066651	TRMT11	100	67.910	ENSIPUG00000017606	trmt11	97	69.432	Ictalurus_punctatus
ENSG00000066651	TRMT11	100	95.032	ENSSTOG00000006671	TRMT11	100	95.032	Ictidomys_tridecemlineatus
ENSG00000066651	TRMT11	100	94.776	ENSJJAG00000017244	-	100	93.305	Jaculus_jaculus
ENSG00000066651	TRMT11	100	68.657	ENSKMAG00000021188	trmt11	96	68.000	Kryptolebias_marmoratus
ENSG00000066651	TRMT11	100	70.896	ENSLBEG00000007644	trmt11	97	67.826	Labrus_bergylta
ENSG00000066651	TRMT11	100	76.119	ENSLACG00000010156	TRMT11	99	73.060	Latimeria_chalumnae
ENSG00000066651	TRMT11	100	72.388	ENSLOCG00000016519	trmt11	98	72.174	Lepisosteus_oculatus
ENSG00000066651	TRMT11	100	94.776	ENSLAFG00000003414	TRMT11	100	93.737	Loxodonta_africana
ENSG00000066651	TRMT11	100	100.000	ENSMFAG00000039916	TRMT11	100	97.624	Macaca_fascicularis
ENSG00000066651	TRMT11	100	100.000	ENSMMUG00000004293	TRMT11	100	97.624	Macaca_mulatta
ENSG00000066651	TRMT11	100	100.000	ENSMNEG00000040840	TRMT11	100	97.624	Macaca_nemestrina
ENSG00000066651	TRMT11	100	100.000	ENSMLEG00000007788	TRMT11	100	97.408	Mandrillus_leucophaeus
ENSG00000066651	TRMT11	100	70.149	ENSMAMG00000024066	trmt11	97	68.490	Mastacembelus_armatus
ENSG00000066651	TRMT11	100	70.149	ENSMZEG00005001961	trmt11	97	68.212	Maylandia_zebra
ENSG00000066651	TRMT11	100	79.851	ENSMGAG00000013262	TRMT11	100	74.675	Meleagris_gallopavo
ENSG00000066651	TRMT11	100	95.699	ENSMAUG00000018053	Trmt11	100	92.657	Mesocricetus_auratus
ENSG00000066651	TRMT11	100	96.269	ENSMICG00000029227	TRMT11	100	95.248	Microcebus_murinus
ENSG00000066651	TRMT11	100	95.699	ENSMOCG00000008176	Trmt11	100	93.089	Microtus_ochrogaster
ENSG00000066651	TRMT11	100	68.657	ENSMMOG00000007742	trmt11	96	67.177	Mola_mola
ENSG00000066651	TRMT11	100	91.045	ENSMODG00000017679	TRMT11	100	87.905	Monodelphis_domestica
ENSG00000066651	TRMT11	100	69.403	ENSMALG00000020514	trmt11	87	68.640	Monopterus_albus
ENSG00000066651	TRMT11	100	93.284	MGP_CAROLIEiJ_G0015212	Trmt11	100	91.793	Mus_caroli
ENSG00000066651	TRMT11	100	92.537	ENSMUSG00000019792	Trmt11	100	91.577	Mus_musculus
ENSG00000066651	TRMT11	100	93.284	MGP_PahariEiJ_G0023834	Trmt11	100	90.497	Mus_pahari
ENSG00000066651	TRMT11	100	92.537	MGP_SPRETEiJ_G0016021	Trmt11	97	90.588	Mus_spretus
ENSG00000066651	TRMT11	100	97.015	ENSMPUG00000014547	TRMT11	78	94.816	Mustela_putorius_furo
ENSG00000066651	TRMT11	100	96.269	ENSMLUG00000008157	TRMT11	99	92.938	Myotis_lucifugus
ENSG00000066651	TRMT11	100	95.699	ENSNGAG00000023826	Trmt11	97	94.524	Nannospalax_galili
ENSG00000066651	TRMT11	100	70.149	ENSNBRG00000010249	trmt11	97	63.333	Neolamprologus_brichardi
ENSG00000066651	TRMT11	100	100.000	ENSNLEG00000014080	TRMT11	100	98.704	Nomascus_leucogenys
ENSG00000066651	TRMT11	100	92.537	ENSMEUG00000008692	TRMT11	100	89.448	Notamacropus_eugenii
ENSG00000066651	TRMT11	100	90.299	ENSODEG00000005552	TRMT11	99	90.260	Octodon_degus
ENSG00000066651	TRMT11	100	69.403	ENSONIG00000007218	trmt11	97	68.212	Oreochromis_niloticus
ENSG00000066651	TRMT11	100	89.552	ENSOANG00000002151	TRMT11	99	82.289	Ornithorhynchus_anatinus
ENSG00000066651	TRMT11	100	97.015	ENSOCUG00000011783	TRMT11	100	94.384	Oryctolagus_cuniculus
ENSG00000066651	TRMT11	100	68.657	ENSORLG00000005779	trmt11	98	66.883	Oryzias_latipes
ENSG00000066651	TRMT11	100	68.657	ENSORLG00020019974	trmt11	98	66.883	Oryzias_latipes_hni
ENSG00000066651	TRMT11	100	69.403	ENSORLG00015004293	trmt11	95	70.290	Oryzias_latipes_hsok
ENSG00000066651	TRMT11	100	69.403	ENSOMEG00000016205	trmt11	97	67.819	Oryzias_melastigma
ENSG00000066651	TRMT11	100	97.015	ENSOGAG00000008764	TRMT11	100	95.464	Otolemur_garnettii
ENSG00000066651	TRMT11	100	95.522	ENSOARG00000007813	TRMT11	99	94.600	Ovis_aries
ENSG00000066651	TRMT11	100	100.000	ENSPPAG00000029635	TRMT11	100	100.000	Pan_paniscus
ENSG00000066651	TRMT11	100	95.522	ENSPPRG00000010751	TRMT11	100	95.248	Panthera_pardus
ENSG00000066651	TRMT11	100	95.522	ENSPTIG00000014927	TRMT11	100	95.248	Panthera_tigris_altaica
ENSG00000066651	TRMT11	100	100.000	ENSPTRG00000018577	TRMT11	100	99.784	Pan_troglodytes
ENSG00000066651	TRMT11	100	100.000	ENSPANG00000022840	TRMT11	100	97.624	Papio_anubis
ENSG00000066651	TRMT11	100	67.910	ENSPKIG00000012868	trmt11	99	68.683	Paramormyrops_kingsleyae
ENSG00000066651	TRMT11	100	81.720	ENSPSIG00000011395	TRMT11	98	79.167	Pelodiscus_sinensis
ENSG00000066651	TRMT11	100	96.269	ENSPEMG00000019414	-	100	93.521	Peromyscus_maniculatus_bairdii
ENSG00000066651	TRMT11	100	57.463	ENSPMAG00000007834	trmt11	99	61.928	Petromyzon_marinus
ENSG00000066651	TRMT11	95	91.339	ENSPCIG00000023970	TRMT11	94	87.817	Phascolarctos_cinereus
ENSG00000066651	TRMT11	100	69.403	ENSPFOG00000018545	trmt11	97	68.282	Poecilia_formosa
ENSG00000066651	TRMT11	100	69.403	ENSPLAG00000015864	trmt11	97	68.062	Poecilia_latipinna
ENSG00000066651	TRMT11	100	68.657	ENSPMEG00000003760	trmt11	97	68.062	Poecilia_mexicana
ENSG00000066651	TRMT11	100	68.657	ENSPREG00000012923	trmt11	97	67.396	Poecilia_reticulata
ENSG00000066651	TRMT11	100	100.000	ENSPPYG00000016990	TRMT11	100	99.352	Pongo_abelii
ENSG00000066651	TRMT11	100	94.600	ENSPCOG00000018890	TRMT11	100	94.600	Propithecus_coquereli
ENSG00000066651	TRMT11	100	70.149	ENSPNYG00000011467	trmt11	97	68.433	Pundamilia_nyererei
ENSG00000066651	TRMT11	100	70.149	ENSPNAG00000001816	trmt11	98	69.114	Pygocentrus_nattereri
ENSG00000066651	TRMT11	100	95.522	ENSRNOG00000014240	Trmt11	99	91.577	Rattus_norvegicus
ENSG00000066651	TRMT11	100	100.000	ENSRBIG00000029483	TRMT11	99	96.087	Rhinopithecus_bieti
ENSG00000066651	TRMT11	100	100.000	ENSRROG00000041258	TRMT11	100	97.408	Rhinopithecus_roxellana
ENSG00000066651	TRMT11	100	32.609	YOL124C	-	99	34.821	Saccharomyces_cerevisiae
ENSG00000066651	TRMT11	100	99.254	ENSSBOG00000026579	TRMT11	100	96.976	Saimiri_boliviensis_boliviensis
ENSG00000066651	TRMT11	100	91.791	ENSSHAG00000016956	TRMT11	100	88.750	Sarcophilus_harrisii
ENSG00000066651	TRMT11	100	69.403	ENSSFOG00015009471	trmt11	98	68.467	Scleropages_formosus
ENSG00000066651	TRMT11	100	69.403	ENSSMAG00000006405	trmt11	97	67.778	Scophthalmus_maximus
ENSG00000066651	TRMT11	100	70.149	ENSSDUG00000012463	trmt11	89	68.282	Seriola_dumerili
ENSG00000066651	TRMT11	100	70.149	ENSSLDG00000014435	trmt11	97	68.282	Seriola_lalandi_dorsalis
ENSG00000066651	TRMT11	100	76.344	ENSSPUG00000003588	TRMT11	99	73.753	Sphenodon_punctatus
ENSG00000066651	TRMT11	100	68.657	ENSSPAG00000021676	trmt11	97	65.974	Stegastes_partitus
ENSG00000066651	TRMT11	100	94.776	ENSSSCG00000004220	TRMT11	88	94.050	Sus_scrofa
ENSG00000066651	TRMT11	100	79.104	ENSTGUG00000011774	TRMT11	100	75.431	Taeniopygia_guttata
ENSG00000066651	TRMT11	100	68.657	ENSTRUG00000004275	trmt11	98	65.659	Takifugu_rubripes
ENSG00000066651	TRMT11	100	70.149	ENSTNIG00000019098	trmt11	97	66.522	Tetraodon_nigroviridis
ENSG00000066651	TRMT11	100	97.015	ENSTTRG00000015658	TRMT11	100	87.284	Tursiops_truncatus
ENSG00000066651	TRMT11	100	97.761	ENSUAMG00000008507	TRMT11	92	95.812	Ursus_americanus
ENSG00000066651	TRMT11	100	97.761	ENSUMAG00000001192	TRMT11	100	96.112	Ursus_maritimus
ENSG00000066651	TRMT11	100	96.774	ENSVPAG00000010506	TRMT11	100	95.204	Vicugna_pacos
ENSG00000066651	TRMT11	100	97.761	ENSVVUG00000000810	TRMT11	100	95.680	Vulpes_vulpes
ENSG00000066651	TRMT11	100	71.949	ENSXETG00000011700	trmt11	97	71.949	Xenopus_tropicalis
ENSG00000066651	TRMT11	98	60.793	ENSXCOG00000016281	trmt11	97	60.793	Xiphophorus_couchianus
ENSG00000066651	TRMT11	100	66.418	ENSXMAG00000008688	trmt11	97	65.859	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000049	tRNA binding	-	IEA	Function
GO:0004809	tRNA (guanine-N2-)-methyltransferase activity	15899842.	EXP	Function
GO:0030488	tRNA methylation	-	IEA	Process