EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000067334 (Gene tree)
Gene ID: 30836
Gene Symbol: DNTTIP2
Alias: HSU15552|ERBP|TdIF2
Full Name: deoxynucleotidyltransferase terminal interacting protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 13,636 bases
Position: chr1:93,866,283-93,879,918
Accession: 24013
RBP type: canonical RBP
Summary: This gene is thought to be involved in chromatin remodeling and gene transcription. The encoded nuclear protein binds to and enhances the transcriptional activity of the estrogen receptor alpha, and also interacts with terminal deoxynucleotidyltransferase. The expression profile of this gene is a potential biomarker for chronic obstructive pulmonary disease. [provided by RefSeq, Dec 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000411010	Fcf2	PF08698.11	1.2e-38	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000496672	DNTTIP2-206	811	-	-	- (aa)	-	-
ENST00000496535	DNTTIP2-205	691	-	-	- (aa)	-	-
ENST00000359208	DNTTIP2-201	2199	-	ENSP00000352137	601 (aa)	-	J3KP30
ENST00000528680	DNTTIP2-207	499	-	ENSP00000434261	161 (aa)	-	E9PRB3
ENST00000460191	DNTTIP2-203	3084	-	-	- (aa)	-	-
ENST00000462746	DNTTIP2-204	480	-	-	- (aa)	-	-
ENST00000436063	DNTTIP2-202	5897	-	ENSP00000411010	756 (aa)	-	Q5QJE6

Gene Model

Click here to download ENSG00000067334's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000067334	Blood Pressure	4.2863917E-005	-
ENSG00000067334	Blood Pressure	4.2420877E-005	-
ENSG00000067334	Platelet Function Tests	1.8950700E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000067334's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000067334	DNTTIP2	99	73.533	ENSAMEG00000009682	DNTTIP2	99	72.621	Ailuropoda_melanoleuca
ENSG00000067334	DNTTIP2	99	89.142	ENSANAG00000031890	DNTTIP2	99	88.204	Aotus_nancymaae
ENSG00000067334	DNTTIP2	99	69.634	ENSBTAG00000047679	DNTTIP2	99	69.503	Bos_taurus
ENSG00000067334	DNTTIP2	99	90.214	ENSCJAG00000017896	DNTTIP2	99	89.276	Callithrix_jacchus
ENSG00000067334	DNTTIP2	99	71.765	ENSCAFG00000020128	DNTTIP2	95	71.838	Canis_familiaris
ENSG00000067334	DNTTIP2	51	82.902	ENSCAFG00020015222	-	97	82.642	Canis_lupus_dingo
ENSG00000067334	DNTTIP2	86	73.874	ENSCAFG00020011923	-	98	72.973	Canis_lupus_dingo
ENSG00000067334	DNTTIP2	99	70.557	ENSCHIG00000009770	DNTTIP2	99	70.690	Capra_hircus
ENSG00000067334	DNTTIP2	99	90.629	ENSCCAG00000025785	DNTTIP2	99	90.763	Cebus_capucinus
ENSG00000067334	DNTTIP2	100	96.565	ENSCATG00000036773	-	100	96.565	Cercocebus_atys
ENSG00000067334	DNTTIP2	99	95.576	ENSCSAG00000001480	DNTTIP2	99	95.576	Chlorocebus_sabaeus
ENSG00000067334	DNTTIP2	100	62.805	ENSCHOG00000013790	DNTTIP2	90	62.282	Choloepus_hoffmanni
ENSG00000067334	DNTTIP2	88	43.094	ENSCPBG00000017394	DNTTIP2	91	43.430	Chrysemys_picta_bellii
ENSG00000067334	DNTTIP2	99	95.174	ENSCANG00000004206	DNTTIP2	99	95.174	Colobus_angolensis_palliatus
ENSG00000067334	DNTTIP2	99	62.891	ENSCGRG00001014053	Dnttip2	99	63.021	Cricetulus_griseus_chok1gshd
ENSG00000067334	DNTTIP2	99	62.891	ENSCGRG00000001002	Dnttip2	99	63.021	Cricetulus_griseus_crigri
ENSG00000067334	DNTTIP2	99	69.935	ENSDNOG00000041868	-	95	69.935	Dasypus_novemcinctus
ENSG00000067334	DNTTIP2	99	63.519	ENSDNOG00000039871	-	99	64.026	Dasypus_novemcinctus
ENSG00000067334	DNTTIP2	98	59.627	ENSETEG00000010714	DNTTIP2	90	55.586	Echinops_telfairi
ENSG00000067334	DNTTIP2	99	66.667	ENSEASG00005015594	DNTTIP2	97	67.224	Equus_asinus_asinus
ENSG00000067334	DNTTIP2	99	67.481	ENSECAG00000022045	DNTTIP2	98	67.224	Equus_caballus
ENSG00000067334	DNTTIP2	90	41.667	ENSFALG00000002291	DNTTIP2	89	41.168	Ficedula_albicollis
ENSG00000067334	DNTTIP2	88	41.436	ENSGAGG00000016254	DNTTIP2	87	41.655	Gopherus_agassizii
ENSG00000067334	DNTTIP2	100	98.942	ENSGGOG00000000575	DNTTIP2	100	98.942	Gorilla_gorilla
ENSG00000067334	DNTTIP2	99	66.885	ENSSTOG00000027499	DNTTIP2	99	67.277	Ictidomys_tridecemlineatus
ENSG00000067334	DNTTIP2	99	64.829	ENSJJAG00000023209	Dnttip2	99	64.829	Jaculus_jaculus
ENSG00000067334	DNTTIP2	96	60.218	ENSLAFG00000004636	DNTTIP2	96	63.302	Loxodonta_africana
ENSG00000067334	DNTTIP2	100	96.697	ENSMFAG00000003472	-	100	96.697	Macaca_fascicularis
ENSG00000067334	DNTTIP2	100	96.697	ENSMMUG00000008435	-	100	96.697	Macaca_mulatta
ENSG00000067334	DNTTIP2	100	96.169	ENSMNEG00000041699	-	100	96.169	Macaca_nemestrina
ENSG00000067334	DNTTIP2	100	96.301	ENSMLEG00000041327	-	100	96.301	Mandrillus_leucophaeus
ENSG00000067334	DNTTIP2	89	40.851	ENSMGAG00000007843	DNTTIP2	98	40.202	Meleagris_gallopavo
ENSG00000067334	DNTTIP2	96	60.533	ENSMAUG00000017681	Dnttip2	100	60.533	Mesocricetus_auratus
ENSG00000067334	DNTTIP2	99	80.053	ENSMICG00000013230	-	99	80.186	Microcebus_murinus
ENSG00000067334	DNTTIP2	99	61.053	ENSMOCG00000020034	Dnttip2	99	61.761	Microtus_ochrogaster
ENSG00000067334	DNTTIP2	91	48.266	ENSMODG00000004761	-	99	46.497	Monodelphis_domestica
ENSG00000067334	DNTTIP2	100	59.016	MGP_CAROLIEiJ_G0025593	Dnttip2	98	58.824	Mus_caroli
ENSG00000067334	DNTTIP2	100	59.823	ENSMUSG00000039756	Dnttip2	99	59.588	Mus_musculus
ENSG00000067334	DNTTIP2	96	56.614	MGP_PahariEiJ_G0027039	Dnttip2	100	57.275	Mus_pahari
ENSG00000067334	DNTTIP2	100	60.153	MGP_SPRETEiJ_G0026544	Dnttip2	99	60.283	Mus_spretus
ENSG00000067334	DNTTIP2	99	71.224	ENSMPUG00000004000	DNTTIP2	99	71.056	Mustela_putorius_furo
ENSG00000067334	DNTTIP2	99	64.369	ENSNGAG00000010947	Dnttip2	99	65.410	Nannospalax_galili
ENSG00000067334	DNTTIP2	100	98.148	ENSNLEG00000010816	DNTTIP2	100	98.148	Nomascus_leucogenys
ENSG00000067334	DNTTIP2	80	44.228	ENSMEUG00000002009	-	81	44.553	Notamacropus_eugenii
ENSG00000067334	DNTTIP2	100	56.522	ENSOPRG00000007058	-	80	63.758	Ochotona_princeps
ENSG00000067334	DNTTIP2	99	69.634	ENSOCUG00000008212	DNTTIP2	99	68.750	Oryctolagus_cuniculus
ENSG00000067334	DNTTIP2	99	76.802	ENSOGAG00000027537	DNTTIP2	99	76.802	Otolemur_garnettii
ENSG00000067334	DNTTIP2	99	69.701	ENSOARG00000016999	DNTTIP2	95	69.571	Ovis_aries
ENSG00000067334	DNTTIP2	100	99.471	ENSPPAG00000044098	DNTTIP2	100	99.471	Pan_paniscus
ENSG00000067334	DNTTIP2	100	99.735	ENSPTRG00000000972	DNTTIP2	100	99.735	Pan_troglodytes
ENSG00000067334	DNTTIP2	100	96.433	ENSPANG00000013362	-	100	96.433	Papio_anubis
ENSG00000067334	DNTTIP2	88	43.273	ENSPSIG00000008273	DNTTIP2	88	43.646	Pelodiscus_sinensis
ENSG00000067334	DNTTIP2	99	62.516	ENSPEMG00000021990	Dnttip2	99	63.220	Peromyscus_maniculatus_bairdii
ENSG00000067334	DNTTIP2	78	76.046	ENSPCIG00000006776	-	87	76.046	Phascolarctos_cinereus
ENSG00000067334	DNTTIP2	100	60.976	ENSPCAG00000015069	DNTTIP2	90	52.316	Procavia_capensis
ENSG00000067334	DNTTIP2	99	80.692	ENSPCOG00000027395	DNTTIP2	99	80.692	Propithecus_coquereli
ENSG00000067334	DNTTIP2	96	73.333	ENSPVAG00000010151	DNTTIP2	90	73.197	Pteropus_vampyrus
ENSG00000067334	DNTTIP2	99	59.663	ENSRNOG00000025025	Dnttip2	99	59.792	Rattus_norvegicus
ENSG00000067334	DNTTIP2	100	92.734	ENSRBIG00000029381	-	99	93.784	Rhinopithecus_bieti
ENSG00000067334	DNTTIP2	100	95.905	ENSRROG00000026979	-	100	95.905	Rhinopithecus_roxellana
ENSG00000067334	DNTTIP2	99	89.424	ENSSBOG00000030305	DNTTIP2	99	89.023	Saimiri_boliviensis_boliviensis
ENSG00000067334	DNTTIP2	89	47.254	ENSSHAG00000004392	-	99	46.154	Sarcophilus_harrisii
ENSG00000067334	DNTTIP2	96	57.547	ENSSARG00000001821	DNTTIP2	91	57.085	Sorex_araneus
ENSG00000067334	DNTTIP2	89	40.103	ENSSPUG00000002461	DNTTIP2	89	40.541	Sphenodon_punctatus
ENSG00000067334	DNTTIP2	99	71.466	ENSSSCG00000006892	DNTTIP2	99	71.466	Sus_scrofa
ENSG00000067334	DNTTIP2	100	63.415	ENSTBEG00000006708	-	67	90.643	Tupaia_belangeri
ENSG00000067334	DNTTIP2	96	73.270	ENSTTRG00000004204	DNTTIP2	90	73.541	Tursiops_truncatus
ENSG00000067334	DNTTIP2	99	73.238	ENSUAMG00000027591	DNTTIP2	95	74.282	Ursus_americanus
ENSG00000067334	DNTTIP2	88	75.146	ENSUMAG00000010202	DNTTIP2	98	75.292	Ursus_maritimus
ENSG00000067334	DNTTIP2	77	93.567	ENSVPAG00000004324	DNTTIP2	74	93.567	Vicugna_pacos
ENSG00000067334	DNTTIP2	99	69.987	ENSVVUG00000021840	DNTTIP2	95	70.077	Vulpes_vulpes

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005730	nucleolus	-	IDA	Component