EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000068654 (Gene tree)
Gene ID: 25885
Gene Symbol: POLR1A
Alias: DKFZP586M0122|FLJ21915|RPO1-4|RPA1
Full Name: RNA polymerase I subunit A
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 85,940 bases
Position: chr2:86,020,216-86,106,155
Accession: 17264
RBP type: canonical RBP
Summary: The protein encoded by this gene is the largest subunit of the RNA polymerase I complex. The encoded protein represents the catalytic subunit of the complex, which transcribes DNA into ribosomal RNA precursors. Defects in this gene are a cause of the Cincinnati type of acrofacial dysostosis. [provided by RefSeq, May 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000386300	RNA_pol_Rpb1_5	PF04998.17	5e-104	1	1
ENSP00000263857	RNA_pol_Rpb1_5	PF04998.17	7.4e-104	1	1
ENSP00000386300	RNA_pol_Rpb1_4	PF05000.17	3.7e-25	1	1
ENSP00000263857	RNA_pol_Rpb1_4	PF05000.17	4e-25	1	1
ENSP00000386300	RNA_pol_Rpb1_2	PF00623.20	1.8e-70	1	1
ENSP00000263857	RNA_pol_Rpb1_2	PF00623.20	1.9e-70	1	1
ENSP00000386300	RNA_pol_Rpb1_3	PF04983.18	9.5e-36	1	1
ENSP00000263857	RNA_pol_Rpb1_3	PF04983.18	1e-35	1	1
ENSP00000386300	RNA_pol_Rpb1_1	PF04997.12	2.9e-22	1	1
ENSP00000263857	RNA_pol_Rpb1_1	PF04997.12	3.3e-22	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
21418567	Heterogeneity in the kinetics of nuclear proteins and trajectories of substructures associated with heterochromatin.	Epigenetics Chromatin	2011 Mar 18	Stixova L	doi: 10.1186/1756-8935-4-5.
29215200	miR-424-5p reduces ribosomal RNA and protein synthesis in muscle wasting.	J Cachexia Sarcopenia Muscle	2018 Apr	Connolly M	doi: 10.1002/jcsm.12266
1846671	Suppressor analysis of temperature-sensitive RNA polymerase I mutations in Saccharomyces cerevisiae: suppression of mutations in a zinc-binding motif by transposed mutant genes.	Mol Cell Biol	1991 Feb	McCusker JH	-
1448093	Cloning and characterization of SRP1, a suppressor of temperature-sensitive RNA polymerase I mutations, in Saccharomyces cerevisiae.	Mol Cell Biol	1992 Dec	Yano R	-
9065685	Identification of the gene coding for the largest subunit of RNA polymerase I (A) of Drosophila melanogaster.	Mol Gen Genet	1997 Feb 20	Knackmuss S	-
20147409	Relocalization of upstream binding factor to viral replication compartments is UL24 independent and follows the onset of herpes simplex virus 1 DNA synthesis.	J Virol	2010 May	Lymberopoulos MH	doi: 10.1128/JVI.02437-09
21399665	The balance between rRNA and ribosomal protein synthesis up- and downregulates the tumour suppressor p53 in mammalian cells.	Oncogene	2011 Jul 21	Donati G	doi: 10.1038/onc.2011.48
28051070	Severe neurodegenerative disease in brothers with homozygous mutation in POLR1A.	Eur J Hum Genet	2017 Feb	Kara B	doi: 10.1038/ejhg.2016.183

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000496892	POLR1A-210	546	-	-	- (aa)	-	-
ENST00000409024	POLR1A-202	560	-	ENSP00000386423	42 (aa)	-	F2Z3I7
ENST00000409681	POLR1A-203	6454	-	ENSP00000386300	1659 (aa)	-	B9ZVN9
ENST00000486964	POLR1A-208	1427	-	-	- (aa)	-	-
ENST00000471427	POLR1A-206	290	-	-	- (aa)	-	-
ENST00000483538	POLR1A-207	593	-	-	- (aa)	-	-
ENST00000462078	POLR1A-205	469	-	-	- (aa)	-	-
ENST00000263857	POLR1A-201	12749	-	ENSP00000263857	1720 (aa)	-	O95602
ENST00000424089	POLR1A-204	576	-	ENSP00000397321	42 (aa)	-	F2Z3I7
ENST00000492034	POLR1A-209	588	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000068654's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03020	RNA polymerase	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000068654	Breast Neoplasms	2.1070000E-004	17529973
ENSG00000068654	Breast Neoplasms	5.6140000E-005	17529973

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000068654	rs3770081	2	86053802	G	Facial emotion recognition (sad faces)	28608620	z score decrease	4.77	EFO_0008329
ENSG00000068654	rs193149448	2	86074514	?	Smoking status	30595370			EFO_0006527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000068654's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000068654	POLR1A	65	32.902	ENSG00000148606	POLR3A	94	38.916

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000068654	POLR1A	71	67.929	ENSAPOG00000017945	polr1a	99	67.929	Acanthochromis_polyacanthus
ENSG00000068654	POLR1A	100	90.872	ENSAMEG00000005807	POLR1A	100	92.008	Ailuropoda_melanoleuca
ENSG00000068654	POLR1A	100	63.889	ENSACIG00000022147	polr1a	100	64.066	Amphilophus_citrinellus
ENSG00000068654	POLR1A	100	65.831	ENSAOCG00000017336	polr1a	100	67.958	Amphiprion_ocellaris
ENSG00000068654	POLR1A	100	65.714	ENSAPEG00000016105	polr1a	100	65.933	Amphiprion_percula
ENSG00000068654	POLR1A	100	66.031	ENSATEG00000016773	polr1a	100	65.954	Anabas_testudineus
ENSG00000068654	POLR1A	86	72.967	ENSAPLG00000013871	POLR1A	99	72.967	Anas_platyrhynchos
ENSG00000068654	POLR1A	99	69.942	ENSACAG00000012141	POLR1A	99	69.469	Anolis_carolinensis
ENSG00000068654	POLR1A	100	94.477	ENSANAG00000033927	POLR1A	100	94.186	Aotus_nancymaae
ENSG00000068654	POLR1A	100	62.154	ENSACLG00000020541	polr1a	100	61.760	Astatotilapia_calliptera
ENSG00000068654	POLR1A	60	72.000	ENSAMXG00000011559	-	83	58.333	Astyanax_mexicanus
ENSG00000068654	POLR1A	100	90.180	ENSBTAG00000006481	POLR1A	100	90.180	Bos_taurus
ENSG00000068654	POLR1A	99	38.715	WBGene00012999	rpoa-1	98	38.457	Caenorhabditis_elegans
ENSG00000068654	POLR1A	100	94.302	ENSCJAG00000019547	POLR1A	100	94.302	Callithrix_jacchus
ENSG00000068654	POLR1A	100	90.656	ENSCAFG00000007613	POLR1A	100	90.587	Canis_familiaris
ENSG00000068654	POLR1A	100	90.451	ENSCAFG00020014752	POLR1A	100	90.382	Canis_lupus_dingo
ENSG00000068654	POLR1A	100	88.123	ENSCHIG00000018204	POLR1A	99	89.126	Capra_hircus
ENSG00000068654	POLR1A	100	90.238	ENSTSYG00000002761	POLR1A	100	89.773	Carlito_syrichta
ENSG00000068654	POLR1A	97	83.840	ENSCAPG00000010132	POLR1A	100	83.931	Cavia_aperea
ENSG00000068654	POLR1A	100	88.269	ENSCPOG00000012350	POLR1A	100	88.560	Cavia_porcellus
ENSG00000068654	POLR1A	100	94.884	ENSCCAG00000019839	POLR1A	100	94.884	Cebus_capucinus
ENSG00000068654	POLR1A	100	97.849	ENSCATG00000029786	POLR1A	100	97.849	Cercocebus_atys
ENSG00000068654	POLR1A	100	88.754	ENSCLAG00000005187	POLR1A	97	91.795	Chinchilla_lanigera
ENSG00000068654	POLR1A	100	97.616	ENSCSAG00000016251	POLR1A	100	97.616	Chlorocebus_sabaeus
ENSG00000068654	POLR1A	60	88.000	ENSCHOG00000003766	-	84	95.294	Choloepus_hoffmanni
ENSG00000068654	POLR1A	99	74.707	ENSCPBG00000001115	POLR1A	99	74.768	Chrysemys_picta_bellii
ENSG00000068654	POLR1A	99	48.221	ENSCSAVG00000007184	-	99	47.898	Ciona_savignyi
ENSG00000068654	POLR1A	100	94.480	ENSCANG00000031785	POLR1A	100	94.480	Colobus_angolensis_palliatus
ENSG00000068654	POLR1A	96	89.825	ENSCGRG00001006651	Polr1a	100	89.825	Cricetulus_griseus_chok1gshd
ENSG00000068654	POLR1A	60	85.742	ENSCGRG00000010834	Polr1a	100	87.053	Cricetulus_griseus_crigri
ENSG00000068654	POLR1A	60	88.000	ENSCGRG00000007004	-	97	84.286	Cricetulus_griseus_crigri
ENSG00000068654	POLR1A	100	62.507	ENSCSEG00000020190	polr1a	100	62.448	Cynoglossus_semilaevis
ENSG00000068654	POLR1A	100	64.713	ENSCVAG00000020941	polr1a	100	64.764	Cyprinodon_variegatus
ENSG00000068654	POLR1A	100	67.034	ENSDARG00000098375	polr1a	100	67.077	Danio_rerio
ENSG00000068654	POLR1A	100	82.957	ENSDNOG00000010829	POLR1A	100	83.014	Dasypus_novemcinctus
ENSG00000068654	POLR1A	100	87.507	ENSDORG00000008298	Polr1a	100	87.912	Dipodomys_ordii
ENSG00000068654	POLR1A	83	44.118	FBgn0019938	RpI1	99	43.442	Drosophila_melanogaster
ENSG00000068654	POLR1A	72	96.875	ENSETEG00000000412	-	72	96.875	Echinops_telfairi
ENSG00000068654	POLR1A	89	47.671	ENSEBUG00000005667	-	99	65.891	Eptatretus_burgeri
ENSG00000068654	POLR1A	100	92.151	ENSEASG00005001625	POLR1A	100	92.151	Equus_asinus_asinus
ENSG00000068654	POLR1A	100	92.151	ENSECAG00000036306	-	100	93.347	Equus_caballus
ENSG00000068654	POLR1A	100	92.151	ENSECAG00000030510	-	100	93.347	Equus_caballus
ENSG00000068654	POLR1A	100	92.151	ENSECAG00000010092	POLR1A	100	93.347	Equus_caballus
ENSG00000068654	POLR1A	81	95.745	ENSEEUG00000000676	POLR1A	85	95.556	Erinaceus_europaeus
ENSG00000068654	POLR1A	100	66.918	ENSELUG00000012769	polr1a	99	66.725	Esox_lucius
ENSG00000068654	POLR1A	100	91.919	ENSFCAG00000008966	POLR1A	100	91.570	Felis_catus
ENSG00000068654	POLR1A	99	71.002	ENSFALG00000010082	POLR1A	99	71.011	Ficedula_albicollis
ENSG00000068654	POLR1A	100	88.560	ENSFDAG00000013726	POLR1A	100	88.095	Fukomys_damarensis
ENSG00000068654	POLR1A	100	61.927	ENSFHEG00000005996	polr1a	100	62.781	Fundulus_heteroclitus
ENSG00000068654	POLR1A	100	60.372	ENSGMOG00000002230	polr1a	100	60.105	Gadus_morhua
ENSG00000068654	POLR1A	90	69.571	ENSGALG00000038160	-	99	69.571	Gallus_gallus
ENSG00000068654	POLR1A	100	64.986	ENSGAFG00000015266	polr1a	100	65.046	Gambusia_affinis
ENSG00000068654	POLR1A	100	64.974	ENSGACG00000018791	polr1a	100	64.974	Gasterosteus_aculeatus
ENSG00000068654	POLR1A	57	72.000	ENSGAGG00000020105	-	76	64.486	Gopherus_agassizii
ENSG00000068654	POLR1A	89	75.442	ENSGAGG00000004984	-	96	81.163	Gopherus_agassizii
ENSG00000068654	POLR1A	100	99.360	ENSGGOG00000001788	POLR1A	100	99.360	Gorilla_gorilla
ENSG00000068654	POLR1A	92	64.617	ENSHBUG00000020021	polr1a	93	75.897	Haplochromis_burtoni
ENSG00000068654	POLR1A	100	88.502	ENSHGLG00000006334	POLR1A	100	88.792	Heterocephalus_glaber_female
ENSG00000068654	POLR1A	100	88.246	ENSHGLG00100006614	POLR1A	100	88.535	Heterocephalus_glaber_male
ENSG00000068654	POLR1A	100	62.587	ENSHCOG00000003345	polr1a	100	62.543	Hippocampus_comes
ENSG00000068654	POLR1A	100	66.140	ENSIPUG00000013174	polr1a	100	66.005	Ictalurus_punctatus
ENSG00000068654	POLR1A	99	87.202	ENSSTOG00000012580	POLR1A	99	87.376	Ictidomys_tridecemlineatus
ENSG00000068654	POLR1A	100	87.014	ENSJJAG00000013113	Polr1a	100	87.246	Jaculus_jaculus
ENSG00000068654	POLR1A	100	65.679	ENSKMAG00000007399	polr1a	100	65.316	Kryptolebias_marmoratus
ENSG00000068654	POLR1A	95	68.392	ENSLBEG00000015401	polr1a	99	68.128	Labrus_bergylta
ENSG00000068654	POLR1A	55	76.931	ENSLACG00000003218	polr1a	100	76.931	Latimeria_chalumnae
ENSG00000068654	POLR1A	100	70.411	ENSLOCG00000010881	polr1a	100	70.116	Lepisosteus_oculatus
ENSG00000068654	POLR1A	100	89.699	ENSLAFG00000014948	POLR1A	100	89.757	Loxodonta_africana
ENSG00000068654	POLR1A	100	97.791	ENSMFAG00000046097	POLR1A	100	97.791	Macaca_fascicularis
ENSG00000068654	POLR1A	100	97.674	ENSMMUG00000015815	POLR1A	100	97.674	Macaca_mulatta
ENSG00000068654	POLR1A	100	97.733	ENSMNEG00000043313	POLR1A	100	97.733	Macaca_nemestrina
ENSG00000068654	POLR1A	100	97.093	ENSMLEG00000042428	POLR1A	100	97.093	Mandrillus_leucophaeus
ENSG00000068654	POLR1A	100	66.198	ENSMAMG00000016565	polr1a	100	66.512	Mastacembelus_armatus
ENSG00000068654	POLR1A	100	65.933	ENSMZEG00005004915	polr1a	100	65.665	Maylandia_zebra
ENSG00000068654	POLR1A	99	69.217	ENSMGAG00000013111	POLR1A	99	69.217	Meleagris_gallopavo
ENSG00000068654	POLR1A	92	87.366	ENSMAUG00000008497	Polr1a	100	87.176	Mesocricetus_auratus
ENSG00000068654	POLR1A	100	92.388	ENSMICG00000000757	POLR1A	97	95.385	Microcebus_murinus
ENSG00000068654	POLR1A	93	94.574	ENSMOCG00000000122	Polr1a	100	87.377	Microtus_ochrogaster
ENSG00000068654	POLR1A	100	65.349	ENSMMOG00000010216	polr1a	100	65.291	Mola_mola
ENSG00000068654	POLR1A	100	75.476	ENSMODG00000009335	POLR1A	100	75.058	Monodelphis_domestica
ENSG00000068654	POLR1A	97	76.410	ENSMALG00000013363	polr1a	100	66.030	Monopterus_albus
ENSG00000068654	POLR1A	100	85.929	MGP_CAROLIEiJ_G0028494	Polr1a	100	85.524	Mus_caroli
ENSG00000068654	POLR1A	100	86.277	ENSMUSG00000049553	Polr1a	100	85.871	Mus_musculus
ENSG00000068654	POLR1A	100	86.335	MGP_PahariEiJ_G0022230	Polr1a	100	85.987	Mus_pahari
ENSG00000068654	POLR1A	100	84.633	MGP_SPRETEiJ_G0029499	Polr1a	95	92.821	Mus_spretus
ENSG00000068654	POLR1A	100	90.523	ENSMPUG00000009135	POLR1A	100	90.465	Mustela_putorius_furo
ENSG00000068654	POLR1A	100	89.589	ENSMLUG00000015723	POLR1A	97	96.410	Myotis_lucifugus
ENSG00000068654	POLR1A	100	87.905	ENSNGAG00000017907	Polr1a	100	88.194	Nannospalax_galili
ENSG00000068654	POLR1A	100	65.459	ENSNBRG00000000519	polr1a	100	65.780	Neolamprologus_brichardi
ENSG00000068654	POLR1A	100	96.181	ENSNLEG00000002264	POLR1A	100	96.181	Nomascus_leucogenys
ENSG00000068654	POLR1A	78	92.126	ENSMEUG00000011665	-	75	92.126	Notamacropus_eugenii
ENSG00000068654	POLR1A	99	82.598	ENSOPRG00000008269	POLR1A	100	82.540	Ochotona_princeps
ENSG00000068654	POLR1A	100	89.199	ENSODEG00000003542	POLR1A	100	89.024	Octodon_degus
ENSG00000068654	POLR1A	100	66.068	ENSONIG00000015895	polr1a	100	66.184	Oreochromis_niloticus
ENSG00000068654	POLR1A	100	90.703	ENSOCUG00000010138	POLR1A	100	90.703	Oryctolagus_cuniculus
ENSG00000068654	POLR1A	100	65.152	ENSORLG00000008753	polr1a	99	65.210	Oryzias_latipes
ENSG00000068654	POLR1A	100	63.811	ENSORLG00020020726	polr1a	99	63.578	Oryzias_latipes_hni
ENSG00000068654	POLR1A	96	74.468	ENSORLG00015016071	polr1a	99	74.444	Oryzias_latipes_hsok
ENSG00000068654	POLR1A	60	72.000	ENSOMEG00000019264	-	100	52.885	Oryzias_melastigma
ENSG00000068654	POLR1A	100	91.047	ENSOGAG00000004031	POLR1A	97	95.385	Otolemur_garnettii
ENSG00000068654	POLR1A	100	89.611	ENSOARG00000020601	POLR1A	100	89.669	Ovis_aries
ENSG00000068654	POLR1A	100	99.128	ENSPPAG00000042450	POLR1A	100	99.128	Pan_paniscus
ENSG00000068654	POLR1A	100	91.919	ENSPPRG00000006702	POLR1A	100	91.570	Panthera_pardus
ENSG00000068654	POLR1A	100	91.367	ENSPTIG00000018783	POLR1A	100	91.020	Panthera_tigris_altaica
ENSG00000068654	POLR1A	100	98.953	ENSPTRG00000012147	POLR1A	100	98.953	Pan_troglodytes
ENSG00000068654	POLR1A	100	97.733	ENSPANG00000025908	POLR1A	100	97.733	Papio_anubis
ENSG00000068654	POLR1A	94	76.389	ENSPKIG00000005468	polr1a	99	76.389	Paramormyrops_kingsleyae
ENSG00000068654	POLR1A	63	70.126	ENSPSIG00000009321	-	99	71.769	Pelodiscus_sinensis
ENSG00000068654	POLR1A	56	68.342	ENSPMGG00000009718	polr1a	95	68.342	Periophthalmus_magnuspinnatus
ENSG00000068654	POLR1A	100	87.898	ENSPEMG00000022224	Polr1a	100	88.130	Peromyscus_maniculatus_bairdii
ENSG00000068654	POLR1A	95	79.101	ENSPCIG00000004222	POLR1A	99	78.480	Phascolarctos_cinereus
ENSG00000068654	POLR1A	100	65.701	ENSPFOG00000005025	polr1a	100	65.643	Poecilia_formosa
ENSG00000068654	POLR1A	100	65.759	ENSPLAG00000021389	polr1a	100	65.701	Poecilia_latipinna
ENSG00000068654	POLR1A	100	63.905	ENSPMEG00000006463	polr1a	100	64.157	Poecilia_mexicana
ENSG00000068654	POLR1A	100	65.585	ENSPREG00000002389	polr1a	100	65.489	Poecilia_reticulata
ENSG00000068654	POLR1A	100	97.674	ENSPPYG00000012217	POLR1A	100	97.674	Pongo_abelii
ENSG00000068654	POLR1A	92	96.000	ENSPCAG00000011582	POLR1A	92	96.000	Procavia_capensis
ENSG00000068654	POLR1A	100	92.214	ENSPCOG00000026987	POLR1A	97	95.897	Propithecus_coquereli
ENSG00000068654	POLR1A	95	92.647	ENSPVAG00000012674	POLR1A	95	91.873	Pteropus_vampyrus
ENSG00000068654	POLR1A	100	65.933	ENSPNYG00000000026	polr1a	100	65.665	Pundamilia_nyererei
ENSG00000068654	POLR1A	100	67.244	ENSPNAG00000019223	polr1a	99	67.551	Pygocentrus_nattereri
ENSG00000068654	POLR1A	100	87.666	ENSRNOG00000009545	Polr1a	100	87.377	Rattus_norvegicus
ENSG00000068654	POLR1A	100	97.035	ENSRBIG00000028335	POLR1A	100	97.035	Rhinopithecus_bieti
ENSG00000068654	POLR1A	100	96.977	ENSRROG00000031473	POLR1A	100	96.977	Rhinopithecus_roxellana
ENSG00000068654	POLR1A	99	36.949	YOR341W	RPA190	99	37.187	Saccharomyces_cerevisiae
ENSG00000068654	POLR1A	100	94.012	ENSSBOG00000030262	POLR1A	100	94.012	Saimiri_boliviensis_boliviensis
ENSG00000068654	POLR1A	100	73.948	ENSSHAG00000014739	POLR1A	100	72.962	Sarcophilus_harrisii
ENSG00000068654	POLR1A	100	67.514	ENSSFOG00015019716	polr1a	100	67.400	Scleropages_formosus
ENSG00000068654	POLR1A	100	66.358	ENSSMAG00000014342	polr1a	100	66.165	Scophthalmus_maximus
ENSG00000068654	POLR1A	100	66.821	ENSSDUG00000014631	polr1a	100	66.821	Seriola_dumerili
ENSG00000068654	POLR1A	100	64.988	ENSSLDG00000024095	polr1a	100	64.986	Seriola_lalandi_dorsalis
ENSG00000068654	POLR1A	78	96.809	ENSSARG00000003136	-	76	96.809	Sorex_araneus
ENSG00000068654	POLR1A	95	77.949	ENSSPUG00000004215	POLR1A	98	78.462	Sphenodon_punctatus
ENSG00000068654	POLR1A	66	71.995	ENSSPAG00000016341	polr1a	94	71.995	Stegastes_partitus
ENSG00000068654	POLR1A	86	91.030	ENSSSCG00000008226	POLR1A	99	91.005	Sus_scrofa
ENSG00000068654	POLR1A	99	69.953	ENSTGUG00000010704	POLR1A	100	69.953	Taeniopygia_guttata
ENSG00000068654	POLR1A	100	64.327	ENSTRUG00000002210	polr1a	99	64.403	Takifugu_rubripes
ENSG00000068654	POLR1A	100	60.552	ENSTNIG00000010116	polr1a	100	60.529	Tetraodon_nigroviridis
ENSG00000068654	POLR1A	74	96.460	ENSTBEG00000008646	POLR1A	74	96.460	Tupaia_belangeri
ENSG00000068654	POLR1A	97	94.359	ENSTTRG00000008597	POLR1A	97	94.359	Tursiops_truncatus
ENSG00000068654	POLR1A	69	91.462	ENSUAMG00000012158	-	94	90.871	Ursus_americanus
ENSG00000068654	POLR1A	60	92.000	ENSUAMG00000000099	-	98	78.417	Ursus_americanus
ENSG00000068654	POLR1A	100	90.233	ENSUMAG00000006700	POLR1A	100	90.058	Ursus_maritimus
ENSG00000068654	POLR1A	100	90.482	ENSVVUG00000001245	POLR1A	100	90.413	Vulpes_vulpes
ENSG00000068654	POLR1A	100	67.326	ENSXETG00000001952	polr1a	100	69.468	Xenopus_tropicalis
ENSG00000068654	POLR1A	100	65.703	ENSXMAG00000004032	polr1a	100	65.761	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001054	RNA polymerase I activity	21873635.	IBA	Function
GO:0001054	RNA polymerase I activity	23782956.	IMP	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003682	chromatin binding	26089203.	IDA	Function
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	21873635.	IBA	Function
GO:0005515	protein binding	16514417.19214185.21555369.25416956.26089203.26496610.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005736	RNA polymerase I complex	21873635.	IBA	Component
GO:0006361	transcription initiation from RNA polymerase I promoter	-	TAS	Process
GO:0006362	transcription elongation from RNA polymerase I promoter	-	TAS	Process
GO:0006363	termination of RNA polymerase I transcription	-	TAS	Process
GO:0008270	zinc ion binding	-	IEA	Function
GO:0045815	positive regulation of gene expression, epigenetic	-	TAS	Process
GO:1904750	negative regulation of protein localization to nucleolus	23782956.	IMP	Process