EuRBPDB

Description

Ensembl ID: ENSG00000071462 (Gene tree)
Gene ID: 114049
Gene Symbol: BUD23
Alias: MGC19709|MGC2022|MGC5140|PP3381|WBMT|MERM1|WBSCR22
Full Name: BUD23 rRNA methyltransferase and ribosome maturation factor
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 22,137 bases
Position: chr7:73,683,025-73,705,161
Accession: 16405
RBP type: non-canonical RBP
Summary: This gene encodes a protein containing a nuclear localization signal and an S-adenosyl-L-methionine binding motif typical of methyltransferases, suggesting that the encoded protein may act on DNA methylation. This gene is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternatively spliced transcript variants have been found. [provided by RefSeq, Feb 2011]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000423497	BUD23-204	1219	-	ENSP00000401191	298 (aa)	-	O43709
ENST00000478670	BUD23-216	572	-	-	- (aa)	-	-
ENST00000453316	BUD23-212	452	-	ENSP00000394852	65 (aa)	-	H7C0G4
ENST00000463307	BUD23-213	1815	-	-	- (aa)	-	-
ENST00000496153	BUD23-218	505	-	-	- (aa)	-	-
ENST00000471215	BUD23-215	3886	-	-	- (aa)	-	-
ENST00000421744	BUD23-203	895	-	ENSP00000404981	100 (aa)	-	F8WD87
ENST00000428163	BUD23-205	577	-	ENSP00000390048	140 (aa)	-	F8WD67
ENST00000421304	BUD23-202	538	-	ENSP00000391761	89 (aa)	-	F8VZ18
ENST00000441822	BUD23-210	632	-	ENSP00000392039	193 (aa)	-	F2Z3D9
ENST00000430446	BUD23-207	738	-	ENSP00000415387	39 (aa)	-	H7C439
ENST00000436944	BUD23-209	2496	-	ENSP00000391410	123 (aa)	-	B3KR83
ENST00000265758	BUD23-201	1230	XM_006715847	ENSP00000265758	281 (aa)	XP_006715910	O43709
ENST00000432522	BUD23-208	1074	-	ENSP00000390136	140 (aa)	-	E9PCQ7
ENST00000430270	BUD23-206	1260	-	ENSP00000398314	67 (aa)	-	F8W1Y1
ENST00000487006	BUD23-217	631	-	-	- (aa)	-	-
ENST00000464615	BUD23-214	458	-	-	- (aa)	-	-
ENST00000442099	BUD23-211	691	-	ENSP00000398732	128 (aa)	-	H7C170

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	25851604.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	21873635.	IBA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0006325	chromatin organization	-	IEA	Process
GO:0008168	methyltransferase activity	11124703.	NAS	Function
GO:0016435	rRNA (guanine) methyltransferase activity	21873635.	IBA	Function
GO:0016435	rRNA (guanine) methyltransferase activity	25851604.	IMP	Function
GO:0031167	rRNA methylation	-	TAS	Process
GO:0046982	protein heterodimerization activity	25851604.	IDA	Function
GO:0048471	perinuclear region of cytoplasm	25851604.	IDA	Component
GO:0070476	rRNA (guanine-N7)-methylation	21873635.	IBA	Process
GO:0070476	rRNA (guanine-N7)-methylation	25851604.	IMP	Process
GO:2000234	positive regulation of rRNA processing	25851604.	IMP	Process