EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000072364 (Gene tree)
Gene ID: 27125
Gene Symbol: AFF4
Alias: AF5Q31|MCEF
Full Name: AF4/FMR2 family member 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 88,284 bases
Position: chr5:132,875,379-132,963,662
Accession: 17869
RBP type: canonical RBP
Summary: The protein encoded by this gene belongs to the AF4 family of transcription factors involved in leukemia. It is a component of the positive transcription elongation factor b (P-TEFb) complex. A chromosomal translocation involving this gene and MLL gene on chromosome 11 is found in infant acute lymphoblastic leukemia with ins(5;11)(q31;q31q23). [provided by RefSeq, Oct 2011]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000265343	AF-4	PF05110.13	0	1	1
ENSP00000367858	AF-4	PF05110.13	6.7e-253	1	1
ENSP00000395268	AF-4	PF05110.13	2.9e-49	1	1
ENSP00000409069	AF-4	PF05110.13	2.1e-48	1	2
ENSP00000409069	AF-4	PF05110.13	2.1e-48	2	2

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
24985467	A single point mutation in cyclin T1 eliminates binding to Hexim1, Cdk9 and RNA but not to AFF4 and enforces repression of HIV transcription.	Retrovirology	2014 Jul 1	Kuzmina A	doi: 10.1186/1742-4690-11-51.
24727379	Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4.	Cell Cycle	2014	Gu J	doi: 10.4161/cc.28756
27731797	Insights into HIV-1 proviral transcription from integrative structure and dynamics of the Tat:AFF4:P-TEFb:TAR complex.	Elife	2016 Oct 12	Schulze-Gahmen U	doi: 10.7554/eLife.15910.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000378593	AFF4-202	430	-	-	- (aa)	-	-
ENST00000378595	AFF4-203	3348	-	ENSP00000367858	900 (aa)	-	Q9UHB7
ENST00000265343	AFF4-201	9552	XM_005271963	ENSP00000265343	1163 (aa)	XP_005272020	Q9UHB7
ENST00000491831	AFF4-209	1667	-	-	- (aa)	-	-
ENST00000478588	AFF4-208	897	-	-	- (aa)	-	-
ENST00000425658	AFF4-205	513	-	ENSP00000409069	171 (aa)	-	H7C319
ENST00000465484	AFF4-206	1729	-	-	- (aa)	-	-
ENST00000421773	AFF4-204	541	-	ENSP00000395268	148 (aa)	-	C9JCE0
ENST00000477369	AFF4-207	728	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000072364's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000072364	rs56398801	5	132892058	T	Itch intensity from mosquito bite adjusted by bite size	28199695	[0.036-0.079] unit increase	0.0577585	EFO_0008377\|EFO_0008378
ENSG00000072364	rs59383773	5	132908776	?	Itch intensity from mosquito bite	28199695	[0.013-0.029] unit decrease	0.0207481	EFO_0008377
ENSG00000072364	rs56398801	5	132892058	T	Itch intensity from mosquito bite adjusted by bite size	28199695	[0.028-0.067] unit increase	0.0479567	EFO_0008377\|EFO_0008378

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000072364's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000072364	AFF4	61	59.341	ENSG00000144218	AFF3	97	50.000
ENSG00000072364	AFF4	59	35.865	ENSG00000172493	AFF1	72	60.204
ENSG00000072364	AFF4	91	55.224	ENSG00000155966	AFF2	65	54.851

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000072364	AFF4	99	61.738	ENSAPOG00000006096	aff4	99	62.469	Acanthochromis_polyacanthus
ENSG00000072364	AFF4	92	42.105	ENSAMEG00000014934	AFF2	71	54.962	Ailuropoda_melanoleuca
ENSG00000072364	AFF4	100	97.297	ENSAMEG00000017764	AFF4	100	96.735	Ailuropoda_melanoleuca
ENSG00000072364	AFF4	61	59.783	ENSAMEG00000015682	-	98	35.890	Ailuropoda_melanoleuca
ENSG00000072364	AFF4	95	44.041	ENSAMEG00000003337	AFF1	78	38.987	Ailuropoda_melanoleuca
ENSG00000072364	AFF4	73	37.448	ENSAMEG00000013204	-	52	39.442	Ailuropoda_melanoleuca
ENSG00000072364	AFF4	58	49.425	ENSACIG00000022732	aff2	50	54.310	Amphilophus_citrinellus
ENSG00000072364	AFF4	89	69.565	ENSACIG00000010592	-	98	66.027	Amphilophus_citrinellus
ENSG00000072364	AFF4	64	55.330	ENSACIG00000010525	aff4	93	53.262	Amphilophus_citrinellus
ENSG00000072364	AFF4	99	62.552	ENSAOCG00000008476	aff4	99	62.198	Amphiprion_ocellaris
ENSG00000072364	AFF4	99	62.552	ENSAPEG00000018275	aff4	99	62.281	Amphiprion_percula
ENSG00000072364	AFF4	99	62.510	ENSATEG00000010963	aff4	99	62.469	Anabas_testudineus
ENSG00000072364	AFF4	57	59.794	ENSAPLG00000003660	-	85	56.827	Anas_platyrhynchos
ENSG00000072364	AFF4	99	38.449	ENSAPLG00000004059	AFF1	99	37.731	Anas_platyrhynchos
ENSG00000072364	AFF4	99	85.897	ENSAPLG00000011166	AFF4	99	86.325	Anas_platyrhynchos
ENSG00000072364	AFF4	99	81.679	ENSACAG00000022605	AFF4	99	82.273	Anolis_carolinensis
ENSG00000072364	AFF4	99	36.907	ENSACAG00000012192	AFF1	99	36.319	Anolis_carolinensis
ENSG00000072364	AFF4	100	98.710	ENSANAG00000037761	AFF4	100	98.710	Aotus_nancymaae
ENSG00000072364	AFF4	98	55.224	ENSANAG00000023509	AFF2	70	54.851	Aotus_nancymaae
ENSG00000072364	AFF4	59	36.212	ENSANAG00000017095	AFF1	81	39.821	Aotus_nancymaae
ENSG00000072364	AFF4	91	72.662	ENSACLG00000011879	aff4	99	60.888	Astatotilapia_calliptera
ENSG00000072364	AFF4	100	59.125	ENSAMXG00000020137	aff4	99	59.144	Astyanax_mexicanus
ENSG00000072364	AFF4	80	45.312	ENSAMXG00000000387	aff2	80	48.734	Astyanax_mexicanus
ENSG00000072364	AFF4	100	96.134	ENSBTAG00000009482	AFF4	100	96.134	Bos_taurus
ENSG00000072364	AFF4	88	55.682	ENSBTAG00000020750	AFF2	58	55.303	Bos_taurus
ENSG00000072364	AFF4	99	37.327	ENSCJAG00000006047	AFF1	81	39.382	Callithrix_jacchus
ENSG00000072364	AFF4	99	100.000	ENSCJAG00000013322	AFF4	100	98.882	Callithrix_jacchus
ENSG00000072364	AFF4	99	98.824	ENSCAFG00000000930	AFF4	100	96.158	Canis_familiaris
ENSG00000072364	AFF4	95	45.596	ENSCAFG00000009476	AFF1	81	38.850	Canis_familiaris
ENSG00000072364	AFF4	100	97.297	ENSCAFG00020000956	AFF4	100	92.096	Canis_lupus_dingo
ENSG00000072364	AFF4	99	98.235	ENSCHIG00000015153	AFF4	100	95.959	Capra_hircus
ENSG00000072364	AFF4	100	98.649	ENSTSYG00000014713	AFF4	100	96.824	Carlito_syrichta
ENSG00000072364	AFF4	98	84.773	ENSCAPG00000013980	AFF4	100	79.038	Cavia_aperea
ENSG00000072364	AFF4	90	46.479	ENSCAPG00000012999	AFF3	54	50.189	Cavia_aperea
ENSG00000072364	AFF4	93	92.335	ENSCPOG00000001814	AFF4	100	90.984	Cavia_porcellus
ENSG00000072364	AFF4	90	46.479	ENSCPOG00000006346	AFF3	64	66.667	Cavia_porcellus
ENSG00000072364	AFF4	99	100.000	ENSCCAG00000030353	AFF4	100	98.710	Cebus_capucinus
ENSG00000072364	AFF4	95	49.704	ENSCCAG00000027623	AFF1	80	36.517	Cebus_capucinus
ENSG00000072364	AFF4	100	100.000	ENSCATG00000044510	AFF4	100	99.312	Cercocebus_atys
ENSG00000072364	AFF4	96	38.159	ENSCATG00000039501	AFF1	80	38.612	Cercocebus_atys
ENSG00000072364	AFF4	85	41.584	ENSCLAG00000017100	AFF3	64	69.697	Chinchilla_lanigera
ENSG00000072364	AFF4	100	94.497	ENSCLAG00000013850	AFF4	100	94.239	Chinchilla_lanigera
ENSG00000072364	AFF4	59	35.994	ENSCSAG00000004333	AFF1	80	38.694	Chlorocebus_sabaeus
ENSG00000072364	AFF4	100	99.324	ENSCSAG00000013682	AFF4	100	98.968	Chlorocebus_sabaeus
ENSG00000072364	AFF4	63	59.722	ENSCHOG00000000041	AFF1	65	59.722	Choloepus_hoffmanni
ENSG00000072364	AFF4	100	96.622	ENSCHOG00000003138	AFF4	91	96.418	Choloepus_hoffmanni
ENSG00000072364	AFF4	99	41.700	ENSCPBG00000020831	AFF2	71	37.581	Chrysemys_picta_bellii
ENSG00000072364	AFF4	53	91.765	ENSCPBG00000016541	-	96	91.765	Chrysemys_picta_bellii
ENSG00000072364	AFF4	91	85.507	ENSCPBG00000016549	-	99	86.798	Chrysemys_picta_bellii
ENSG00000072364	AFF4	99	41.000	ENSCPBG00000005382	AFF1	99	38.462	Chrysemys_picta_bellii
ENSG00000072364	AFF4	96	37.688	ENSCANG00000037514	AFF1	77	40.125	Colobus_angolensis_palliatus
ENSG00000072364	AFF4	100	99.324	ENSCANG00000030350	AFF4	100	98.968	Colobus_angolensis_palliatus
ENSG00000072364	AFF4	100	92.453	ENSCGRG00001016680	Aff4	100	93.053	Cricetulus_griseus_chok1gshd
ENSG00000072364	AFF4	100	91.424	ENSCGRG00000008529	Aff4	100	92.024	Cricetulus_griseus_crigri
ENSG00000072364	AFF4	63	54.255	ENSCGRG00000003408	Aff3	64	65.152	Cricetulus_griseus_crigri
ENSG00000072364	AFF4	99	60.753	ENSCSEG00000017002	aff4	99	60.717	Cynoglossus_semilaevis
ENSG00000072364	AFF4	99	57.322	ENSCVAG00000005218	aff4	99	57.275	Cyprinodon_variegatus
ENSG00000072364	AFF4	99	56.757	ENSDARG00000001857	aff4	99	55.574	Danio_rerio
ENSG00000072364	AFF4	59	35.894	ENSDNOG00000048783	-	99	40.000	Dasypus_novemcinctus
ENSG00000072364	AFF4	100	96.220	ENSDNOG00000016669	AFF4	100	96.220	Dasypus_novemcinctus
ENSG00000072364	AFF4	82	97.541	ENSDORG00000023279	-	100	97.541	Dipodomys_ordii
ENSG00000072364	AFF4	92	54.478	ENSDORG00000015215	Aff2	69	54.104	Dipodomys_ordii
ENSG00000072364	AFF4	99	32.171	ENSDORG00000007294	Aff3	64	68.182	Dipodomys_ordii
ENSG00000072364	AFF4	80	38.085	ENSDORG00000013881	Aff1	81	38.067	Dipodomys_ordii
ENSG00000072364	AFF4	91	94.815	ENSETEG00000000128	AFF4	76	98.462	Echinops_telfairi
ENSG00000072364	AFF4	53	38.272	ENSETEG00000014905	AFF1	70	39.578	Echinops_telfairi
ENSG00000072364	AFF4	98	39.602	ENSEBUG00000012097	aff4	65	55.172	Eptatretus_burgeri
ENSG00000072364	AFF4	100	97.297	ENSEASG00005018361	AFF4	100	96.220	Equus_asinus_asinus
ENSG00000072364	AFF4	100	97.297	ENSECAG00000011969	AFF4	100	96.392	Equus_caballus
ENSG00000072364	AFF4	88	100.000	ENSEEUG00000011214	AFF4	94	100.000	Erinaceus_europaeus
ENSG00000072364	AFF4	86	77.432	ENSELUG00000023871	aff4	91	78.599	Esox_lucius
ENSG00000072364	AFF4	100	97.297	ENSFCAG00000012425	AFF4	100	97.079	Felis_catus
ENSG00000072364	AFF4	95	43.455	ENSFCAG00000029806	AFF1	78	38.438	Felis_catus
ENSG00000072364	AFF4	90	54.962	ENSFCAG00000004117	AFF2	70	54.962	Felis_catus
ENSG00000072364	AFF4	99	36.068	ENSFALG00000005554	AFF1	78	36.901	Ficedula_albicollis
ENSG00000072364	AFF4	99	81.090	ENSFALG00000008916	AFF4	94	84.908	Ficedula_albicollis
ENSG00000072364	AFF4	100	94.067	ENSFDAG00000005342	AFF4	100	93.723	Fukomys_damarensis
ENSG00000072364	AFF4	98	40.523	ENSFDAG00000011981	AFF2	57	53.875	Fukomys_damarensis
ENSG00000072364	AFF4	99	56.669	ENSFHEG00000004526	aff4	99	55.666	Fundulus_heteroclitus
ENSG00000072364	AFF4	91	65.753	ENSGMOG00000008803	aff4	89	60.526	Gadus_morhua
ENSG00000072364	AFF4	99	42.105	ENSGALG00000009168	AFF2	67	38.937	Gallus_gallus
ENSG00000072364	AFF4	86	57.831	ENSGALG00000043935	AFF1	63	57.831	Gallus_gallus
ENSG00000072364	AFF4	99	84.157	ENSGALG00000030147	AFF4	100	85.000	Gallus_gallus
ENSG00000072364	AFF4	99	57.741	ENSGAFG00000005288	aff4	99	58.908	Gambusia_affinis
ENSG00000072364	AFF4	94	66.216	ENSGACG00000020734	aff4	100	61.102	Gasterosteus_aculeatus
ENSG00000072364	AFF4	61	53.763	ENSGAGG00000024556	-	91	37.059	Gopherus_agassizii
ENSG00000072364	AFF4	99	85.934	ENSGAGG00000020214	AFF4	100	86.189	Gopherus_agassizii
ENSG00000072364	AFF4	66	54.082	ENSGAGG00000025416	-	97	42.037	Gopherus_agassizii
ENSG00000072364	AFF4	61	39.750	ENSGAGG00000016287	-	96	40.617	Gopherus_agassizii
ENSG00000072364	AFF4	64	53.608	ENSGAGG00000003871	-	92	36.963	Gopherus_agassizii
ENSG00000072364	AFF4	100	100.000	ENSGGOG00000011786	AFF4	100	99.914	Gorilla_gorilla
ENSG00000072364	AFF4	91	72.662	ENSHBUG00000021987	aff4	99	60.804	Haplochromis_burtoni
ENSG00000072364	AFF4	99	97.647	ENSHGLG00000006661	AFF4	100	94.497	Heterocephalus_glaber_female
ENSG00000072364	AFF4	92	43.275	ENSHGLG00000000634	AFF2	69	54.851	Heterocephalus_glaber_female
ENSG00000072364	AFF4	99	97.647	ENSHGLG00100018576	AFF4	100	94.319	Heterocephalus_glaber_male
ENSG00000072364	AFF4	54	55.224	ENSHGLG00100010140	AFF2	80	54.851	Heterocephalus_glaber_male
ENSG00000072364	AFF4	91	40.107	ENSHGLG00100016607	AFF1	78	35.331	Heterocephalus_glaber_male
ENSG00000072364	AFF4	99	60.972	ENSHCOG00000016280	aff4	99	62.028	Hippocampus_comes
ENSG00000072364	AFF4	95	64.865	ENSIPUG00000011689	aff4	100	56.235	Ictalurus_punctatus
ENSG00000072364	AFF4	51	56.000	ENSSTOG00000006530	AFF1	77	39.918	Ictidomys_tridecemlineatus
ENSG00000072364	AFF4	100	97.973	ENSSTOG00000026695	AFF4	100	99.180	Ictidomys_tridecemlineatus
ENSG00000072364	AFF4	99	36.805	ENSSTOG00000012140	AFF3	60	68.182	Ictidomys_tridecemlineatus
ENSG00000072364	AFF4	95	37.838	ENSJJAG00000022877	Aff1	70	37.415	Jaculus_jaculus
ENSG00000072364	AFF4	99	37.275	ENSJJAG00000013155	Aff3	64	69.697	Jaculus_jaculus
ENSG00000072364	AFF4	99	91.660	ENSJJAG00000000912	Aff4	99	91.574	Jaculus_jaculus
ENSG00000072364	AFF4	99	60.050	ENSKMAG00000010443	aff4	99	58.853	Kryptolebias_marmoratus
ENSG00000072364	AFF4	99	61.782	ENSLBEG00000017778	aff4	99	62.052	Labrus_bergylta
ENSG00000072364	AFF4	99	42.217	ENSLACG00000007303	AFF1	99	40.347	Latimeria_chalumnae
ENSG00000072364	AFF4	100	75.827	ENSLACG00000008849	AFF4	100	75.148	Latimeria_chalumnae
ENSG00000072364	AFF4	55	54.982	ENSLACG00000010860	aff2	80	55.019	Latimeria_chalumnae
ENSG00000072364	AFF4	99	68.519	ENSLOCG00000010610	aff4	99	69.613	Lepisosteus_oculatus
ENSG00000072364	AFF4	91	56.204	ENSLOCG00000015403	aff2	88	56.985	Lepisosteus_oculatus
ENSG00000072364	AFF4	92	55.224	ENSLAFG00000018691	AFF2	87	48.299	Loxodonta_africana
ENSG00000072364	AFF4	51	36.820	ENSLAFG00000015880	-	96	35.656	Loxodonta_africana
ENSG00000072364	AFF4	100	96.131	ENSLAFG00000010555	AFF4	100	96.131	Loxodonta_africana
ENSG00000072364	AFF4	96	37.531	ENSMFAG00000037700	AFF1	80	38.514	Macaca_fascicularis
ENSG00000072364	AFF4	100	100.000	ENSMFAG00000034615	AFF4	100	99.226	Macaca_fascicularis
ENSG00000072364	AFF4	61	59.341	ENSMMUG00000037520	-	80	59.341	Macaca_mulatta
ENSG00000072364	AFF4	100	100.000	ENSMMUG00000015640	AFF4	100	99.226	Macaca_mulatta
ENSG00000072364	AFF4	99	38.350	ENSMMUG00000014076	AFF1	65	55.200	Macaca_mulatta
ENSG00000072364	AFF4	96	38.238	ENSMNEG00000031536	AFF1	80	38.514	Macaca_nemestrina
ENSG00000072364	AFF4	100	100.000	ENSMNEG00000033381	AFF4	100	99.226	Macaca_nemestrina
ENSG00000072364	AFF4	100	100.000	ENSMLEG00000028953	AFF4	100	93.723	Mandrillus_leucophaeus
ENSG00000072364	AFF4	59	35.994	ENSMLEG00000039099	AFF1	80	38.710	Mandrillus_leucophaeus
ENSG00000072364	AFF4	94	69.178	ENSMAMG00000021453	aff4	99	62.895	Mastacembelus_armatus
ENSG00000072364	AFF4	91	72.662	ENSMZEG00005003218	aff4	99	60.888	Maylandia_zebra
ENSG00000072364	AFF4	55	50.000	ENSMZEG00005005467	-	92	34.247	Maylandia_zebra
ENSG00000072364	AFF4	99	93.567	ENSMGAG00000009144	AFF4	100	86.496	Meleagris_gallopavo
ENSG00000072364	AFF4	54	53.455	ENSMGAG00000008246	-	95	42.027	Meleagris_gallopavo
ENSG00000072364	AFF4	61	52.747	ENSMGAG00000008263	-	96	35.959	Meleagris_gallopavo
ENSG00000072364	AFF4	99	37.480	ENSMGAG00000007646	AFF1	98	35.155	Meleagris_gallopavo
ENSG00000072364	AFF4	87	89.497	ENSMAUG00000013669	Aff4	100	89.497	Mesocricetus_auratus
ENSG00000072364	AFF4	92	55.072	ENSMICG00000011580	AFF2	71	55.147	Microcebus_murinus
ENSG00000072364	AFF4	99	96.599	ENSMICG00000030374	-	88	94.463	Microcebus_murinus
ENSG00000072364	AFF4	99	98.824	ENSMICG00000002753	-	100	96.303	Microcebus_murinus
ENSG00000072364	AFF4	100	93.643	ENSMOCG00000003884	Aff4	100	93.643	Microtus_ochrogaster
ENSG00000072364	AFF4	99	57.479	ENSMMOG00000013763	aff4	71	51.680	Mola_mola
ENSG00000072364	AFF4	69	45.370	ENSMMOG00000010019	aff2	53	53.543	Mola_mola
ENSG00000072364	AFF4	98	37.811	ENSMODG00000020745	AFF1	75	37.551	Monodelphis_domestica
ENSG00000072364	AFF4	100	88.481	ENSMODG00000013842	AFF4	100	89.164	Monodelphis_domestica
ENSG00000072364	AFF4	99	60.199	ENSMALG00000017690	aff4	99	61.635	Monopterus_albus
ENSG00000072364	AFF4	92	44.444	MGP_CAROLIEiJ_G0033123	Aff2	73	54.851	Mus_caroli
ENSG00000072364	AFF4	100	91.838	MGP_CAROLIEiJ_G0016331	Aff4	100	94.262	Mus_caroli
ENSG00000072364	AFF4	96	38.523	MGP_CAROLIEiJ_G0014063	Aff3	59	50.190	Mus_caroli
ENSG00000072364	AFF4	100	91.931	ENSMUSG00000049470	Aff4	99	96.203	Mus_musculus
ENSG00000072364	AFF4	96	38.523	ENSMUSG00000037138	Aff3	54	65.152	Mus_musculus
ENSG00000072364	AFF4	92	43.860	ENSMUSG00000031189	Aff2	88	53.875	Mus_musculus
ENSG00000072364	AFF4	98	54.851	MGP_PahariEiJ_G0031666	Aff2	88	54.478	Mus_pahari
ENSG00000072364	AFF4	100	91.760	MGP_PahariEiJ_G0017466	Aff4	100	95.082	Mus_pahari
ENSG00000072364	AFF4	100	92.017	MGP_SPRETEiJ_G0017175	Aff4	100	96.203	Mus_spretus
ENSG00000072364	AFF4	92	44.444	MGP_SPRETEiJ_G0034278	Aff2	88	53.875	Mus_spretus
ENSG00000072364	AFF4	100	94.773	ENSMPUG00000010316	AFF4	99	96.607	Mustela_putorius_furo
ENSG00000072364	AFF4	86	49.242	ENSMLUG00000015255	AFF3	59	39.934	Myotis_lucifugus
ENSG00000072364	AFF4	98	54.167	ENSMLUG00000010364	AFF2	89	53.558	Myotis_lucifugus
ENSG00000072364	AFF4	95	44.041	ENSMLUG00000000293	AFF1	81	38.224	Myotis_lucifugus
ENSG00000072364	AFF4	100	95.619	ENSMLUG00000015081	AFF4	100	95.619	Myotis_lucifugus
ENSG00000072364	AFF4	99	36.635	ENSNGAG00000002408	Aff3	54	68.182	Nannospalax_galili
ENSG00000072364	AFF4	100	92.354	ENSNGAG00000019867	Aff4	100	91.838	Nannospalax_galili
ENSG00000072364	AFF4	89	71.852	ENSNBRG00000006285	-	97	65.193	Neolamprologus_brichardi
ENSG00000072364	AFF4	100	99.398	ENSNLEG00000012874	AFF4	100	99.398	Nomascus_leucogenys
ENSG00000072364	AFF4	99	78.000	ENSMEUG00000006620	-	77	88.713	Notamacropus_eugenii
ENSG00000072364	AFF4	77	100.000	ENSOPRG00000014519	AFF4	77	100.000	Ochotona_princeps
ENSG00000072364	AFF4	92	37.129	ENSOPRG00000010133	AFF2	66	48.611	Ochotona_princeps
ENSG00000072364	AFF4	86	35.991	ENSOPRG00000017154	-	51	39.185	Ochotona_princeps
ENSG00000072364	AFF4	100	93.981	ENSODEG00000008137	AFF4	100	94.067	Octodon_degus
ENSG00000072364	AFF4	92	42.105	ENSODEG00000009737	AFF2	52	30.447	Octodon_degus
ENSG00000072364	AFF4	90	70.803	ENSONIG00000008446	aff4	99	61.455	Oreochromis_niloticus
ENSG00000072364	AFF4	82	48.125	ENSOANG00000001095	-	86	57.678	Ornithorhynchus_anatinus
ENSG00000072364	AFF4	99	86.916	ENSOANG00000007428	AFF4	95	87.511	Ornithorhynchus_anatinus
ENSG00000072364	AFF4	100	95.365	ENSOCUG00000013635	AFF4	100	95.365	Oryctolagus_cuniculus
ENSG00000072364	AFF4	51	37.288	ENSOCUG00000002105	AFF1	77	38.408	Oryctolagus_cuniculus
ENSG00000072364	AFF4	99	58.983	ENSORLG00000001361	aff4	99	59.762	Oryzias_latipes
ENSG00000072364	AFF4	99	59.068	ENSORLG00020020601	aff4	99	59.847	Oryzias_latipes_hni
ENSG00000072364	AFF4	99	59.237	ENSORLG00015004684	aff4	99	60.017	Oryzias_latipes_hsok
ENSG00000072364	AFF4	99	58.883	ENSOMEG00000005078	aff4	99	59.372	Oryzias_melastigma
ENSG00000072364	AFF4	98	39.091	ENSOGAG00000016333	AFF2	51	36.726	Otolemur_garnettii
ENSG00000072364	AFF4	99	96.599	ENSOGAG00000028482	AFF4	100	94.931	Otolemur_garnettii
ENSG00000072364	AFF4	88	55.682	ENSOARG00000009528	AFF2	56	55.303	Ovis_aries
ENSG00000072364	AFF4	100	95.959	ENSOARG00000013406	AFF4	100	95.959	Ovis_aries
ENSG00000072364	AFF4	100	100.000	ENSPPAG00000043255	AFF4	100	99.828	Pan_paniscus
ENSG00000072364	AFF4	99	37.236	ENSPPAG00000029196	AFF1	50	40.320	Pan_paniscus
ENSG00000072364	AFF4	100	97.297	ENSPPRG00000016213	AFF4	100	97.079	Panthera_pardus
ENSG00000072364	AFF4	90	54.962	ENSPPRG00000019488	AFF2	70	54.962	Panthera_pardus
ENSG00000072364	AFF4	95	43.850	ENSPPRG00000023590	AFF1	77	38.987	Panthera_pardus
ENSG00000072364	AFF4	95	43.850	ENSPTIG00000011838	AFF1	73	52.381	Panthera_tigris_altaica
ENSG00000072364	AFF4	100	97.297	ENSPTIG00000016209	AFF4	100	97.079	Panthera_tigris_altaica
ENSG00000072364	AFF4	100	100.000	ENSPTRG00000046486	-	100	99.828	Pan_troglodytes
ENSG00000072364	AFF4	91	55.224	ENSPTRG00000022353	AFF2	65	54.851	Pan_troglodytes
ENSG00000072364	AFF4	100	100.000	ENSPTRG00000017228	AFF4	100	99.828	Pan_troglodytes
ENSG00000072364	AFF4	99	37.236	ENSPTRG00000016255	AFF1	54	58.571	Pan_troglodytes
ENSG00000072364	AFF4	100	100.000	ENSPANG00000007039	AFF4	100	99.226	Papio_anubis
ENSG00000072364	AFF4	97	36.794	ENSPANG00000016722	AFF1	79	36.419	Papio_anubis
ENSG00000072364	AFF4	99	59.272	ENSPKIG00000024325	AFF4	99	58.256	Paramormyrops_kingsleyae
ENSG00000072364	AFF4	99	61.298	ENSPKIG00000024249	AFF4	99	58.972	Paramormyrops_kingsleyae
ENSG00000072364	AFF4	92	46.073	ENSPSIG00000010309	AFF2	97	39.247	Pelodiscus_sinensis
ENSG00000072364	AFF4	99	84.058	ENSPSIG00000013003	AFF4	100	84.314	Pelodiscus_sinensis
ENSG00000072364	AFF4	61	57.778	ENSPMGG00000006477	aff4	99	59.478	Periophthalmus_magnuspinnatus
ENSG00000072364	AFF4	51	50.000	ENSPMGG00000003738	AFF2	54	48.800	Periophthalmus_magnuspinnatus
ENSG00000072364	AFF4	89	63.043	ENSPMGG00000006483	-	98	61.878	Periophthalmus_magnuspinnatus
ENSG00000072364	AFF4	100	93.729	ENSPEMG00000007995	Aff4	100	93.729	Peromyscus_maniculatus_bairdii
ENSG00000072364	AFF4	99	36.174	ENSPEMG00000014802	Aff3	64	65.152	Peromyscus_maniculatus_bairdii
ENSG00000072364	AFF4	89	38.710	ENSPMAG00000007807	aff4	99	38.613	Petromyzon_marinus
ENSG00000072364	AFF4	100	88.642	ENSPCIG00000000197	AFF4	100	88.728	Phascolarctos_cinereus
ENSG00000072364	AFF4	99	59.144	ENSPFOG00000007079	aff4	99	59.294	Poecilia_formosa
ENSG00000072364	AFF4	99	59.228	ENSPLAG00000001837	aff4	99	59.714	Poecilia_latipinna
ENSG00000072364	AFF4	99	59.596	ENSPMEG00000005613	aff4	99	59.580	Poecilia_mexicana
ENSG00000072364	AFF4	99	59.262	ENSPREG00000005287	aff4	99	59.412	Poecilia_reticulata
ENSG00000072364	AFF4	100	100.000	ENSPPYG00000015775	AFF4	100	99.742	Pongo_abelii
ENSG00000072364	AFF4	58	51.894	ENSPCAG00000015472	AFF2	53	51.493	Procavia_capensis
ENSG00000072364	AFF4	64	55.000	ENSPCAG00000005658	AFF1	53	55.000	Procavia_capensis
ENSG00000072364	AFF4	94	92.899	ENSPCAG00000003995	AFF4	94	92.899	Procavia_capensis
ENSG00000072364	AFF4	91	55.224	ENSPCOG00000013963	AFF2	82	54.851	Propithecus_coquereli
ENSG00000072364	AFF4	100	95.701	ENSPCOG00000023876	AFF4	100	95.701	Propithecus_coquereli
ENSG00000072364	AFF4	76	45.378	ENSPVAG00000006065	AFF2	53	45.378	Pteropus_vampyrus
ENSG00000072364	AFF4	100	96.223	ENSPVAG00000015204	AFF4	100	96.223	Pteropus_vampyrus
ENSG00000072364	AFF4	91	72.662	ENSPNYG00000014804	aff4	99	60.804	Pundamilia_nyererei
ENSG00000072364	AFF4	100	59.278	ENSPNAG00000004777	aff4	100	59.197	Pygocentrus_nattereri
ENSG00000072364	AFF4	100	92.440	ENSRNOG00000006965	Aff4	100	92.440	Rattus_norvegicus
ENSG00000072364	AFF4	94	43.229	ENSRNOG00000002232	Aff1	53	38.880	Rattus_norvegicus
ENSG00000072364	AFF4	94	51.190	ENSRBIG00000032242	AFF1	80	39.222	Rhinopithecus_bieti
ENSG00000072364	AFF4	100	100.000	ENSRBIG00000029376	AFF4	100	96.647	Rhinopithecus_bieti
ENSG00000072364	AFF4	94	44.560	ENSRROG00000045716	AFF1	80	39.321	Rhinopithecus_roxellana
ENSG00000072364	AFF4	100	100.000	ENSRROG00000033812	AFF4	100	99.140	Rhinopithecus_roxellana
ENSG00000072364	AFF4	100	98.796	ENSSBOG00000021562	AFF4	100	98.796	Saimiri_boliviensis_boliviensis
ENSG00000072364	AFF4	61	59.783	ENSSHAG00000014244	-	91	37.716	Sarcophilus_harrisii
ENSG00000072364	AFF4	99	47.753	ENSSHAG00000009556	AFF2	94	38.529	Sarcophilus_harrisii
ENSG00000072364	AFF4	99	95.906	ENSSHAG00000013198	AFF4	100	88.642	Sarcophilus_harrisii
ENSG00000072364	AFF4	86	55.042	ENSSFOG00015009105	-	95	55.042	Scleropages_formosus
ENSG00000072364	AFF4	61	61.806	ENSSFOG00015000846	AFF4	100	59.272	Scleropages_formosus
ENSG00000072364	AFF4	85	67.969	ENSSFOG00015000839	-	100	62.035	Scleropages_formosus
ENSG00000072364	AFF4	99	63.336	ENSSFOG00015018646	aff4	99	63.929	Scleropages_formosus
ENSG00000072364	AFF4	94	68.966	ENSSMAG00000004734	aff4	99	62.781	Scophthalmus_maximus
ENSG00000072364	AFF4	99	61.060	ENSSDUG00000019498	aff4	99	62.437	Seriola_dumerili
ENSG00000072364	AFF4	99	61.226	ENSSLDG00000007683	aff4	99	62.437	Seriola_lalandi_dorsalis
ENSG00000072364	AFF4	83	95.935	ENSSARG00000011190	AFF4	77	86.076	Sorex_araneus
ENSG00000072364	AFF4	99	36.683	ENSSPUG00000001574	AFF1	99	36.838	Sphenodon_punctatus
ENSG00000072364	AFF4	99	81.491	ENSSPUG00000012215	AFF4	100	81.748	Sphenodon_punctatus
ENSG00000072364	AFF4	67	63.106	ENSSPAG00000012370	aff4	99	63.106	Stegastes_partitus
ENSG00000072364	AFF4	89	68.841	ENSSPAG00000012349	-	98	66.391	Stegastes_partitus
ENSG00000072364	AFF4	99	98.830	ENSSSCG00000014291	AFF4	100	96.048	Sus_scrofa
ENSG00000072364	AFF4	88	55.303	ENSSSCG00000012730	AFF2	59	54.924	Sus_scrofa
ENSG00000072364	AFF4	99	36.520	ENSTGUG00000002726	AFF1	99	35.987	Taeniopygia_guttata
ENSG00000072364	AFF4	92	41.919	ENSTGUG00000004690	AFF2	82	37.887	Taeniopygia_guttata
ENSG00000072364	AFF4	57	61.798	ENSTGUG00000010070	-	84	34.516	Taeniopygia_guttata
ENSG00000072364	AFF4	99	84.147	ENSTGUG00000000187	AFF4	100	83.548	Taeniopygia_guttata
ENSG00000072364	AFF4	99	61.564	ENSTRUG00000008087	aff4	99	61.218	Takifugu_rubripes
ENSG00000072364	AFF4	70	34.292	ENSTNIG00000007537	-	54	45.211	Tetraodon_nigroviridis
ENSG00000072364	AFF4	99	60.756	ENSTNIG00000018201	aff4	99	60.537	Tetraodon_nigroviridis
ENSG00000072364	AFF4	92	33.333	ENSTBEG00000010934	AFF2	70	49.802	Tupaia_belangeri
ENSG00000072364	AFF4	87	93.798	ENSTBEG00000012172	AFF4	76	85.787	Tupaia_belangeri
ENSG00000072364	AFF4	95	45.596	ENSTTRG00000005595	AFF1	78	40.125	Tursiops_truncatus
ENSG00000072364	AFF4	100	94.845	ENSTTRG00000014729	AFF4	100	94.845	Tursiops_truncatus
ENSG00000072364	AFF4	100	97.297	ENSUAMG00000025984	AFF4	100	96.735	Ursus_americanus
ENSG00000072364	AFF4	71	37.374	ENSUMAG00000025433	AFF1	51	58.333	Ursus_maritimus
ENSG00000072364	AFF4	100	97.297	ENSUMAG00000017952	AFF4	100	90.714	Ursus_maritimus
ENSG00000072364	AFF4	73	35.071	ENSUMAG00000007823	-	57	40.319	Ursus_maritimus
ENSG00000072364	AFF4	100	95.615	ENSVPAG00000007247	AFF4	100	95.615	Vicugna_pacos
ENSG00000072364	AFF4	60	35.655	ENSVPAG00000004007	AFF1	81	37.688	Vicugna_pacos
ENSG00000072364	AFF4	95	45.596	ENSVVUG00000009263	AFF1	81	38.988	Vulpes_vulpes
ENSG00000072364	AFF4	99	98.824	ENSVVUG00000024524	AFF4	100	96.647	Vulpes_vulpes
ENSG00000072364	AFF4	55	45.627	ENSXETG00000030016	AFF3	99	47.638	Xenopus_tropicalis
ENSG00000072364	AFF4	99	38.532	ENSXETG00000019630	aff2	68	56.818	Xenopus_tropicalis
ENSG00000072364	AFF4	99	73.457	ENSXETG00000004169	aff4	66	77.070	Xenopus_tropicalis
ENSG00000072364	AFF4	63	53.753	ENSXCOG00000006385	aff4	97	54.021	Xiphophorus_couchianus
ENSG00000072364	AFF4	89	63.830	ENSXCOG00000006382	-	99	61.749	Xiphophorus_couchianus
ENSG00000072364	AFF4	71	33.698	ENSXMAG00000004657	-	60	43.846	Xiphophorus_maculatus
ENSG00000072364	AFF4	99	58.878	ENSXMAG00000001642	aff4	99	59.278	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001650	fibrillar center	-	IDA	Component
GO:0003690	double-stranded DNA binding	21873635.	IBA	Function
GO:0003700	DNA-binding transcription factor activity	21873635.	IBA	Function
GO:0005515	protein binding	20153263.21729782.22190034.25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006355	regulation of transcription, DNA-templated	-	IEA	Process
GO:0006366	transcription by RNA polymerase II	-	TAS	Process
GO:0006368	transcription elongation from RNA polymerase II promoter	-	TAS	Process
GO:0007286	spermatid development	-	IEA	Process
GO:0008023	transcription elongation factor complex	21873635.	IBA	Component
GO:0008023	transcription elongation factor complex	22195968.	IDA	Component
GO:0032783	ELL-EAF complex	21873635.	IBA	Component
GO:0035327	transcriptionally active chromatin	-	ISS	Component