EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000073578 (Gene tree)
Gene ID: 6389
Gene Symbol: SDHA
Alias: FP|SDHF|SDH2
Full Name: succinate dehydrogenase complex flavoprotein subunit A
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 46,594 bases
Position: chr5:218,223-264,816
Accession: 10680
RBP type: non-canonical RBP
Summary: This gene encodes a major catalytic subunit of succinate-ubiquinone oxidoreductase, a complex of the mitochondrial respiratory chain. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. Mutations in this gene have been associated with a form of mitochondrial respiratory chain deficiency known as Leigh Syndrome. A pseudogene has been identified on chromosome 3q29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000509564	SDHA-211	630	-	ENSP00000421911	101 (aa)	-	H0Y8S2
ENST00000510361	SDHA-213	2148	XM_024446143	ENSP00000427703	616 (aa)	XP_024301911	P31040
ENST00000507266	SDHA-207	432	-	-	- (aa)	-	-
ENST00000509082	SDHA-209	434	-	-	- (aa)	-	-
ENST00000512962	SDHA-215	935	-	-	- (aa)	-	-
ENST00000514233	SDHA-217	558	-	-	- (aa)	-	-
ENST00000505555	SDHA-206	2230	-	-	- (aa)	-	-
ENST00000617470	SDHA-220	1952	-	ENSP00000484230	519 (aa)	-	A0A087X1I3
ENST00000509632	SDHA-212	583	-	ENSP00000425077	89 (aa)	-	D6REB7
ENST00000511810	SDHA-214	3001	-	-	- (aa)	-	-
ENST00000515752	SDHA-218	1809	-	-	- (aa)	-	-
ENST00000514027	SDHA-216	2209	-	-	- (aa)	-	-
ENST00000504309	SDHA-204	2067	XM_011514073	ENSP00000426514	583 (aa)	XP_011512375	D6RFM5
ENST00000503674	SDHA-203	2426	-	-	- (aa)	-	-
ENST00000502379	SDHA-202	679	-	-	- (aa)	-	-
ENST00000504824	SDHA-205	1430	-	-	- (aa)	-	-
ENST00000515815	SDHA-219	704	-	ENSP00000422404	126 (aa)	-	H0Y8X1
ENST00000264932	SDHA-201	2390	XM_011514072	ENSP00000264932	664 (aa)	XP_011512374	P31040
ENST00000507522	SDHA-208	644	-	-	- (aa)	-	-
ENST00000509420	SDHA-210	580	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000073578's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00020	Citrate cycle (TCA cycle)	KEGG
hsa00190	Oxidative phosphorylation	KEGG
hsa01100	Metabolic pathways	KEGG
hsa01200	Carbon metabolism	KEGG
hsa04714	Thermogenesis	KEGG
hsa04932	Non-alcoholic fatty liver disease (NAFLD)	KEGG
hsa05010	Alzheimer disease	KEGG
hsa05012	Parkinson disease	KEGG
hsa05016	Huntington disease	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000073578's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000073578	SDHA	93	77.311	WBGene00015391	sdha-1	96	73.034	Caenorhabditis_elegans
ENSG00000073578	SDHA	100	76.879	FBgn0261439	SdhA	100	73.874	Drosophila_melanogaster
ENSG00000073578	SDHA	100	96.701	ENSMUSG00000021577	Sdha	99	96.667	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000104	succinate dehydrogenase activity	21873635.	IBA	Function
GO:0000104	succinate dehydrogenase activity	7550341.	IMP	Function
GO:0005515	protein binding	15961414.19628817.19688755.23747254.24606901.26496610.26749241.28330616.	IPI	Function
GO:0005730	nucleolus	-	IDA	Component
GO:0005739	mitochondrion	7550341.16826196.	IDA	Component
GO:0005743	mitochondrial inner membrane	-	ISS	Component
GO:0005743	mitochondrial inner membrane	-	TAS	Component
GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	21873635.	IBA	Component
GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	-	ISS	Component
GO:0005749	mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)	7550341.	TAS	Component
GO:0006099	tricarboxylic acid cycle	21873635.	IBA	Process
GO:0006099	tricarboxylic acid cycle	-	IEA	Process
GO:0006099	tricarboxylic acid cycle	7550341.	TAS	Process
GO:0006105	succinate metabolic process	7550341.	IDA	Process
GO:0006121	mitochondrial electron transport, succinate to ubiquinone	21873635.	IBA	Process
GO:0007399	nervous system development	16361598.	IMP	Process
GO:0008177	succinate dehydrogenase (ubiquinone) activity	21873635.	IBA	Function
GO:0008177	succinate dehydrogenase (ubiquinone) activity	24781757.	IMP	Function
GO:0009055	electron transfer activity	21873635.	IBA	Function
GO:0022904	respiratory electron transport chain	7550341.	IDA	Process
GO:0045282	plasma membrane succinate dehydrogenase complex	21873635.	IBA	Component
GO:0050660	flavin adenine dinucleotide binding	21873635.	IBA	Function
GO:0055114	oxidation-reduction process	7550341.	IDA	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
28260082	Cancer-associated fibroblasts enhance pancreatic cancer cell invasion by remodeling the metabolic conversion mechanism.	Oncol Rep	2017 Apr	Shan T	doi: 10.3892/or.2017.5479
26259135	Succinate Dehydrogenase (SDH)-Deficient Pancreatic Neuroendocrine Tumor Expands the SDH-Related Tumor Spectrum.	J Clin Endocrinol Metab	2015 Oct	Niemeijer ND	doi: 10.1210/jc.2015-2689
19644226	Regulation of succinate-ubiquinone reductase and fumarate reductase activities in human complex II by phosphorylation of its flavoprotein subunit.	Proc Jpn Acad Ser B Phys Biol Sci	2009	Tomitsuka E	-
23174333	The role of complex II in disease.	Biochim Biophys Acta	2013 May	Hoekstra AS	doi: 10.1016/j.bbabio.2012.11.005
22677546	Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors.	Genes Dev	2012 Jun 15	Xiao M	doi: 10.1101/gad.191056.112
22955521	Loss of expression of SDHA predicts SDHA mutations in gastrointestinal stromal tumors.	Mod Pathol	2013 Feb	Wagner AJ	doi: 10.1038/modpathol.2012.153
27587393	The Assembly Factor SDHAF2 Is Dispensable for Flavination of the Catalytic Subunit of Mitochondrial Complex II in Breast Cancer Cells.	J Biol Chem	2016 Oct 7	Bezawork-Geleta A	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr5	236468	Missense_Mutation	novel	G434D	0.42
BLCA	chr5	236487	Silent	NA	E440E	0.29
BLCA	chr5	224411	Missense_Mutation	novel	G68C	0.4
BLCA	chr5	224412	Missense_Mutation	novel	G68V	0.4
BLCA	chr5	235159	Missense_Mutation	novel	E360D	0.08
BLCA	chr5	235283	Missense_Mutation	NA	V402L	0.25
BLCA	chr5	225551	Missense_Mutation	rs575617625	A149T	0.1
BLCA	chr5	225445	Missense_Mutation	novel	N113K	0.19
BLCA	chr5	240407	Missense_Mutation	NA	M494I	0.25
BLCA	chr5	256422	3'UTR	novel		0.24
BLCA	chr5	256404	Frame_Shift_Del	novel	*I661Ffs21**	0.59
BLCA	chr5	256475	3'UTR	novel		0.2
BLCA	chr5	228306	Missense_Mutation	NA	R248T	0.34
BRCA	chr5	236519	Missense_Mutation	rs370690436	R451H	0.29
BRCA	chr5	230935	Missense_Mutation	rs367721665	T277M	0.13
BRCA	chr5	223563	Missense_Mutation	novel	D49N	0.05
BRCA	chr5	235370	Intron	novel		0.69
CESC	chr5	224387	Missense_Mutation	NA	H60Y	0.12
CESC	chr5	251421	Missense_Mutation	novel	E583K	0.29
CESC	chr5	225911	Missense_Mutation	NA	R162T	0.12
CESC	chr5	236487	Silent	NA	E440E	0.12
CESC	chr5	224460	Missense_Mutation	rs199615452	G84E	0.25
CESC	chr5	225548	Missense_Mutation	rs375576259	A148T	0.38
CESC	chr5	233810	Intron	novel		0.19
CESC	chr5	236564	Missense_Mutation	NA	A466V	0.06
CESC	chr5	251704	Intron	novel		0.37
CESC	chr5	228238	Silent	NA	L225L	0.34
COAD	chr5	233572	Missense_Mutation	rs200526913	A331T	0.46
COAD	chr5	251013	Missense_Mutation	novel	V525M	0.14
COAD	chr5	251004	Missense_Mutation	NA	H522N	0.25
COAD	chr5	235255	Silent	rs1041950	G392G	0.31
COAD	chr5	251596	Intron	novel		0.27
COAD	chr5	225938	Missense_Mutation	rs587782076	R171H	0.41
COAD	chr5	251452	Missense_Mutation	novel	A593V	0.38
COAD	chr5	224432	Nonsense_Mutation	rs781764920	R75*	0.33
COAD	chr5	251031	Missense_Mutation	rs371056571	V531M	0.23
COAD	chr5	230884	Missense_Mutation	NA	G260V	0.28
COAD	chr5	235214	Missense_Mutation	rs749309213	R379C	0.17
COAD	chr5	224366	Missense_Mutation	NA	A53T	0.39
COAD	chr5	235349	Intron	novel		0.3
COAD	chr5	251414	Nonsense_Mutation	NA	Y580*	0.5
COAD	chr5	228269	Missense_Mutation	rs774160524	A236T	0.26
COAD	chr5	233559	Missense_Mutation	novel	F326L	0.05
COAD	chr5	251440	Missense_Mutation	rs763766162	R589Q	0.18
COAD	chr5	228219	Missense_Mutation	rs756877901	Y219C	0.29
COAD	chr5	235312	Silent	rs376530094	G411G	0.1
COAD	chr5	235376	Intron	novel		0.07
ESCA	chr5	256567	3'UTR	novel		0.06
ESCA	chr5	233645	Missense_Mutation	novel	R355K	0.6
GBM	chr5	251526	Intron	novel		0.07
GBM	chr5	235332	Missense_Mutation	novel	K418R	0.69
GBM	chr5	235333	Missense_Mutation	novel	K418N	0.68
GBM	chr5	225887	Missense_Mutation	novel	E154A	0.05
GBM	chr5	224467	Missense_Mutation	novel	N86K	0.28
GBM	chr5	223525	Missense_Mutation	novel	T36N	0.14
GBM	chr5	233603	Missense_Mutation	novel	D341V	0.1
GBM	chr5	235364	Intron	novel		0.19
GBM	chr5	235330	Nonsense_Mutation	novel	Y417*	0.07
HNSC	chr5	251507	Intron	novel		0.4
HNSC	chr5	225997	Missense_Mutation	novel	C191R	0.14
HNSC	chr5	236335	Intron	novel		0.29
HNSC	chr5	251018	Silent	novel	F526F	0.18
HNSC	chr5	233510	Missense_Mutation	rs760542965	G310E	0.38
KICH	chr5	235226	Missense_Mutation	novel	I383F	0.08
KIRC	chr5	233652	Splice_Region	novel		0.17
KIRP	chr5	224471	Missense_Mutation	NA	A88T	0.17
LAML	chr5	224456	Missense_Mutation	novel	A83P	0.04
LGG	chr5	225416	Splice_Region	novel		0.3
LGG	chr5	218356	Translation_Start_Site	rs1061517	M1?	0.36
LGG	chr5	218356	Translation_Start_Site	rs1061517	M1?	0.42
LGG	chr5	251524	Intron	novel		0.11
LIHC	chr5	223567	Missense_Mutation	NA	S50F	0.24
LIHC	chr5	251388	Missense_Mutation	NA	M572L	0.24
LIHC	chr5	240460	Missense_Mutation	NA	R512L	0.43
LUAD	chr5	225973	Missense_Mutation	novel	G183S	0.22
LUAD	chr5	251421	Missense_Mutation	NA	E583Q	0.04
LUAD	chr5	251103	Nonsense_Mutation	novel	G555*	0.36
LUAD	chr5	236433	Silent	NA	L422L	0.15
LUAD	chr5	225497	Missense_Mutation	novel	D131Y	0.23
LUAD	chr5	224428	Silent	novel	G73G	0.04
LUAD	chr5	218270	5'UTR	novel		0.43
LUAD	chr5	256482	3'UTR	novel		0.21
LUAD	chr5	251013	Missense_Mutation	novel	V525M	0.07
LUAD	chr5	236466	Silent	rs144473374	P433P	0.25
LUAD	chr5	235215	Missense_Mutation	novel	R379L	0.09
LUAD	chr5	240392	Silent	NA	G489G	0.21
LUSC	chr5	251098	Missense_Mutation	novel	D553V	0.08
LUSC	chr5	240466	Missense_Mutation	novel	S514I	0.07
LUSC	chr5	218333	5'UTR	novel		0.33
LUSC	chr5	218293	5'UTR	novel		0.67
LUSC	chr5	251373	Missense_Mutation	novel	E567Q	0.13
LUSC	chr5	225526	Missense_Mutation	rs747232441	H140Q	0.08
LUSC	chr5	228159	Intron	novel		0.34
LUSC	chr5	225434	Missense_Mutation	NA	A110S	0.21
LUSC	chr5	233673	Intron	novel		0.04
LUSC	chr5	225967	Missense_Mutation	novel	G181R	0.31
LUSC	chr5	228242	Missense_Mutation	novel	E227Q	0.08
LUSC	chr5	256437	3'UTR	novel		0.09
LUSC	chr5	233728	Intron	novel		0.57
OV	chr5	236539	Silent	novel	L458L	0.23
OV	chr5	223535	Silent	novel	G39G	0.12
OV	chr5	230965	Nonsense_Mutation	novel	C287*	0.12
OV	chr5	230966	Frame_Shift_Ins	novel	*Q288Tfs33**	0.06
OV	chr5	233593	Missense_Mutation	novel	A338P	0.07
PAAD	chr5	228219	Frame_Shift_Ins	novel	*A221Cfs100**	0.08
PAAD	chr5	235169	Missense_Mutation	rs372738835	V364I	0.11
PAAD	chr5	251446	Missense_Mutation	rs367621815	A591V	0.19
PCPG	chr5	256383	Missense_Mutation	novel	D653A	0.06
PRAD	chr5	228204	Missense_Mutation	rs755432673	S214N	0.39
PRAD	chr5	233566	Nonsense_Mutation	NA	R329*	0.42
READ	chr5	251546	Intron	novel		0.18
READ	chr5	225473	Missense_Mutation	NA	F123I	0.47
READ	chr5	228306	Missense_Mutation	NA	R248T	0.25
READ	chr5	228257	Missense_Mutation	NA	R232C	0.21
READ	chr5	235374	Intron	novel		0.41
SARC	chr5	251395	Missense_Mutation	novel	C574S	0.39
SARC	chr5	224427	Missense_Mutation	novel	G73D	0.04
SKCM	chr5	225520	Silent	NA	A138A	0.38
SKCM	chr5	225988	Missense_Mutation	rs553257776	R188W	0.47
SKCM	chr5	223541	Silent	novel	K41K	0.84
SKCM	chr5	235291	Silent	NA	P404P	0.37
SKCM	chr5	236422	Splice_Region	novel		0.25
SKCM	chr5	251004	Missense_Mutation	NA	H522Y	0.05
SKCM	chr5	233653	Splice_Region	novel		0.07
SKCM	chr5	225891	Missense_Mutation	NA	N155K	0.14
SKCM	chr5	256423	3'UTR	novel		0.53
SKCM	chr5	256335	Missense_Mutation	novel	V637A	0.05
SKCM	chr5	233646	Splice_Site	novel	X355_splice	0.34
SKCM	chr5	225422	Missense_Mutation	novel	G106R	0.14
SKCM	chr5	225423	Missense_Mutation	novel	G106E	0.14
SKCM	chr5	230961	Missense_Mutation	novel	P286S	0.24
SKCM	chr5	233515	Missense_Mutation	novel	R312C	0.36
SKCM	chr5	226022	Missense_Mutation	novel	S199L	0.38
SKCM	chr5	233583	Silent	rs144252500	A334A	0.44
STAD	chr5	240451	Missense_Mutation	rs397514541	S509L	0.23
STAD	chr5	230882	Silent	rs140243793	Y259Y	0.26
STAD	chr5	233554	Missense_Mutation	NA	R325G	0.36
STAD	chr5	230955	Missense_Mutation	novel	G284C	0.17
STAD	chr5	233595	Silent	rs201341132	A338A	0.28
STAD	chr5	240386	Silent	rs187540602	N487N	0.29
STAD	chr5	235147	Silent	novel	G356G	0.42
STAD	chr5	235295	Missense_Mutation	NA	V406M	0.17
STAD	chr5	235386	Intron	novel		0.1
STAD	chr5	235168	Silent	rs368488126	H363H	0.36
STAD	chr5	230886	Missense_Mutation	rs143484394	R261C	0.25
STAD	chr5	218371	Missense_Mutation	novel	G6S	0.15
STAD	chr5	256376	Missense_Mutation	rs375396913	E651K	0.19
STAD	chr5	230883	Missense_Mutation	novel	G260R	0.14
STAD	chr5	251100	Missense_Mutation	rs9809219	R554W	0.35
STAD	chr5	240446	Silent	NA	R507R	0.09
STAD	chr5	225941	Missense_Mutation	NA	A172V	0.07
UCEC	chr5	228085	Intron	novel		0.32
UCEC	chr5	235431	Intron	novel		0.39
UCEC	chr5	233734	Intron	novel		0.18
UCEC	chr5	235267	Silent	rs778667374	T396T	0.44
UCEC	chr5	225535	Silent	NA	T143T	0.46
UCEC	chr5	233530	Missense_Mutation	novel	I317V	0.37
UCEC	chr5	235274	Missense_Mutation	novel	P399S	0.23
UCEC	chr5	233796	Intron	novel		0.67
UCEC	chr5	235376	Intron	novel		0.45
UCEC	chr5	225903	Silent	rs771741537	P159P	0.2
UCEC	chr5	228269	Missense_Mutation	rs774160524	A236T	0.13
UCEC	chr5	235169	Missense_Mutation	rs372738835	V364I	0.24
UCEC	chr5	235272	Missense_Mutation	novel	E398G	0.1
UCEC	chr5	240360	Missense_Mutation	NA	D479N	0.16
UCEC	chr5	240451	Missense_Mutation	rs397514541	S509L	0.28
UCEC	chr5	251096	Silent	NA	F552F	0.13
UCEC	chr5	235297	Silent	novel	V406V	0.25
UCEC	chr5	225454	Missense_Mutation	novel	E116D	0.09
UCEC	chr5	227924	Intron	novel		0.69
UCEC	chr5	233787	Intron	novel		0.15
UCEC	chr5	235438	Intron	novel		0.39
UCEC	chr5	251013	Missense_Mutation	novel	V525M	0.2
UCEC	chr5	230906	Silent	rs543630901	T267T	0.12
UCEC	chr5	228093	Intron	novel		0.36
UCEC	chr5	228217	Silent	novel	E218E	0.32
UCEC	chr5	251424	Missense_Mutation	NA	A584T	0.18
UCEC	chr5	225505	Frame_Shift_Del	novel	*D135Tfs8**	0.47
UCEC	chr5	225533	Missense_Mutation	novel	T143A	0.38
UCEC	chr5	230970	Missense_Mutation	novel	D289Y	0.45
UCEC	chr5	235401	Intron	novel		0.48
UCEC	chr5	228258	Missense_Mutation	NA	R232H	0.38
UCEC	chr5	233811	Intron	novel		0.35
UCEC	chr5	251486	Intron	novel		0.27
UCEC	chr5	228178	Splice_Region	novel		0.32
UCEC	chr5	235408	Intron	novel		0.38
UCEC	chr5	240387	Missense_Mutation	rs369100772	A488T	0.19
UCEC	chr5	251097	Missense_Mutation	rs769882609	D553N	0.18
UCEC	chr5	227976	Intron	novel		0.54
UCEC	chr5	251649	Intron	novel		0.24
UCEC	chr5	235163	Missense_Mutation	novel	D362Y	0.35
UCEC	chr5	233618	Missense_Mutation	novel	S346F	0.39
UCEC	chr5	256594	3'UTR	novel		0.36
UCEC	chr5	235255	Silent	rs1041950	G392G	0.19
UCEC	chr5	236523	Silent	rs748496836	L452L	0.47
UCEC	chr5	235152	Missense_Mutation	novel	G358D	0.09
UCEC	chr5	256360	Silent	NA	I645I	0.29
UCEC	chr5	225482	Missense_Mutation	NA	T126P	0.23
UCEC	chr5	228249	Missense_Mutation	NA	G229E	0.14
UCEC	chr5	233566	Nonsense_Mutation	NA	R329*	0.48
UCEC	chr5	228294	Missense_Mutation	novel	I244T	0.47
UCEC	chr5	233489	Missense_Mutation	NA	A303V	0.15
UCEC	chr5	233516	Missense_Mutation	novel	R312H	0.45
UCEC	chr5	233796	Intron	novel		0.29
UCEC	chr5	233693	Intron	novel		0.35
UCEC	chr5	225562	Missense_Mutation	novel	E152D	0.06
UCEC	chr5	235431	Intron	novel		0.27
UCS	chr5	240416	Missense_Mutation	novel	D497E	0.06
UCS	chr5	251339	Splice_Region	novel	G555G	0.33

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
BLCA	AMP	0.4632	7.3103e-07
BRCA	AMP	0.3148	0.12333
CESC	AMP	0.4508	2.0057e-06
ESCA	AMP	0.4946	0.00042289
HNSC	AMP	0.3985	6.6095e-05
KIRP	DEL	0.0208	0.09673
LGG	DEL	0.078	0.0003285
LUSC	AMP	0.7226	3.3442e-18
OV	AMP	0.4905	3.6333e-11
SARC	DEL	0.1089	0.054392
SKCM	DEL	0.1281	0.011094
STAD	AMP	0.2426	0.0018322
TGCT	DEL	0.5667	0.098913
THCA	DEL	0	0.23456
UCEC	AMP	0.1429	4.6983e-05

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00086	Kaplan-Meier Survival Analysis
STAD	0.0088	Kaplan-Meier Survival Analysis
ACC	0.0046	Kaplan-Meier Survival Analysis
HNSC	0.033	Kaplan-Meier Survival Analysis
BRCA	0.0064	Kaplan-Meier Survival Analysis
KIRP	0.0001	Kaplan-Meier Survival Analysis
LAML	0.0001	Kaplan-Meier Survival Analysis
KICH	0.017	Kaplan-Meier Survival Analysis
LGG	0.00015	Kaplan-Meier Survival Analysis
LUAD	0.047	Kaplan-Meier Survival Analysis
UVM	0.00015	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742