EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000074356 (Gene tree)
Gene ID: 55421
Gene Symbol: NCBP3
Alias: HSA277841|ELG|C17orf85
Full Name: nuclear cap binding subunit 3
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 44,092 bases
Position: chr17:3,802,160-3,846,251
Accession: 24612
RBP type: canonical RBP
Summary: (Nuclear Cap Binding Subunit 3) is a Protein Coding gene.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000373657	NCBP3	PF10309.9	8.8e-20	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
29703953	Structural analysis of human ARS2 asa platform for co-transcriptional RNA sorting.	Nat Commun	2018 Apr 27	Schulze WM	doi: 10.1038/s41467-018-04142-7.

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000577169	NCBP3-207	645	-	-	- (aa)	-	-
ENST00000576523	NCBP3-206	249	-	ENSP00000466165	80 (aa)	-	K7ELP6
ENST00000574911	NCBP3-204	2701	XM_017024828	ENSP00000467742	36 (aa)	XP_016880317	K7EQA5
ENST00000389005	NCBP3-201	12770	XM_005256717	ENSP00000373657	620 (aa)	XP_005256774	Q53F19
ENST00000575815	NCBP3-205	4096	-	-	- (aa)	-	-
ENST00000572988	NCBP3-202	518	-	-	- (aa)	-	-
ENST00000574379	NCBP3-203	918	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000074356's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000074356	Body Mass Index	7.268e-005	19060910
ENSG00000074356	Insulin-Like Growth Factor Binding Protein 1	9.0310000E-005	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000074356's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000074356	NCBP3	99	57.477	ENSAPOG00000020809	ncbp3	98	58.003	Acanthochromis_polyacanthus
ENSG00000074356	NCBP3	98	89.839	ENSAMEG00000009372	NCBP3	98	90.323	Ailuropoda_melanoleuca
ENSG00000074356	NCBP3	98	54.428	ENSACIG00000024257	ncbp3	98	56.522	Amphilophus_citrinellus
ENSG00000074356	NCBP3	99	56.854	ENSAPEG00000020857	ncbp3	98	57.845	Amphiprion_percula
ENSG00000074356	NCBP3	98	55.000	ENSATEG00000010801	ncbp3	98	56.986	Anabas_testudineus
ENSG00000074356	NCBP3	90	79.167	ENSAPLG00000007373	NCBP3	98	79.893	Anas_platyrhynchos
ENSG00000074356	NCBP3	99	69.726	ENSANAG00000020550	-	97	69.357	Aotus_nancymaae
ENSG00000074356	NCBP3	98	90.774	ENSANAG00000024918	-	98	91.461	Aotus_nancymaae
ENSG00000074356	NCBP3	99	56.897	ENSACLG00000000455	ncbp3	98	57.143	Astatotilapia_calliptera
ENSG00000074356	NCBP3	98	56.785	ENSAMXG00000005968	ncbp3	98	58.382	Astyanax_mexicanus
ENSG00000074356	NCBP3	98	92.904	ENSBTAG00000016621	NCBP3	98	93.069	Bos_taurus
ENSG00000074356	NCBP3	100	95.000	ENSCAFG00000019371	NCBP3	95	92.525	Canis_familiaris
ENSG00000074356	NCBP3	100	95.000	ENSCAFG00020008143	NCBP3	95	92.525	Canis_lupus_dingo
ENSG00000074356	NCBP3	100	93.548	ENSCHIG00000009002	NCBP3	98	93.729	Capra_hircus
ENSG00000074356	NCBP3	100	97.097	ENSTSYG00000008184	NCBP3	100	97.097	Carlito_syrichta
ENSG00000074356	NCBP3	89	93.989	ENSCAPG00000016045	NCBP3	95	94.171	Cavia_aperea
ENSG00000074356	NCBP3	98	93.729	ENSCPOG00000015529	NCBP3	98	93.894	Cavia_porcellus
ENSG00000074356	NCBP3	100	98.065	ENSCCAG00000021154	NCBP3	100	98.065	Cebus_capucinus
ENSG00000074356	NCBP3	100	100.000	ENSCATG00000013041	NCBP3	95	98.173	Cercocebus_atys
ENSG00000074356	NCBP3	100	95.323	ENSCLAG00000012229	NCBP3	100	95.323	Chinchilla_lanigera
ENSG00000074356	NCBP3	98	94.234	ENSCSAG00000013543	NCBP3	98	94.563	Chlorocebus_sabaeus
ENSG00000074356	NCBP3	98	90.594	ENSCHOG00000012323	NCBP3	98	91.089	Choloepus_hoffmanni
ENSG00000074356	NCBP3	100	79.133	ENSCPBG00000014824	NCBP3	97	81.455	Chrysemys_picta_bellii
ENSG00000074356	NCBP3	98	88.449	ENSCANG00000033561	NCBP3	100	89.355	Colobus_angolensis_palliatus
ENSG00000074356	NCBP3	98	92.916	ENSCGRG00001018538	Ncbp3	98	93.081	Cricetulus_griseus_chok1gshd
ENSG00000074356	NCBP3	88	93.211	ENSCGRG00000015075	Ncbp3	97	93.394	Cricetulus_griseus_crigri
ENSG00000074356	NCBP3	99	56.347	ENSCSEG00000006375	ncbp3	98	56.804	Cynoglossus_semilaevis
ENSG00000074356	NCBP3	99	50.870	ENSCVAG00000020563	ncbp3	98	51.198	Cyprinodon_variegatus
ENSG00000074356	NCBP3	98	53.546	ENSDARG00000044597	ncbp3	98	55.137	Danio_rerio
ENSG00000074356	NCBP3	100	92.500	ENSDNOG00000006490	NCBP3	95	92.857	Dasypus_novemcinctus
ENSG00000074356	NCBP3	100	93.065	ENSDORG00000010141	Ncbp3	98	93.069	Dipodomys_ordii
ENSG00000074356	NCBP3	100	91.250	ENSEASG00005013399	NCBP3	95	93.854	Equus_asinus_asinus
ENSG00000074356	NCBP3	100	92.500	ENSECAG00000008444	NCBP3	95	94.020	Equus_caballus
ENSG00000074356	NCBP3	98	74.050	ENSEEUG00000008573	NCBP3	96	73.311	Erinaceus_europaeus
ENSG00000074356	NCBP3	100	54.481	ENSELUG00000009182	ncbp3	98	54.928	Esox_lucius
ENSG00000074356	NCBP3	98	93.564	ENSFCAG00000007929	NCBP3	98	93.729	Felis_catus
ENSG00000074356	NCBP3	92	80.944	ENSFALG00000006704	NCBP3	98	81.930	Ficedula_albicollis
ENSG00000074356	NCBP3	98	94.389	ENSFDAG00000013355	NCBP3	98	94.554	Fukomys_damarensis
ENSG00000074356	NCBP3	98	51.807	ENSFHEG00000005607	ncbp3	98	51.520	Fundulus_heteroclitus
ENSG00000074356	NCBP3	72	60.656	ENSGMOG00000001007	ncbp3	77	59.344	Gadus_morhua
ENSG00000074356	NCBP3	100	78.491	ENSGALG00000002653	NCBP3	98	80.000	Gallus_gallus
ENSG00000074356	NCBP3	84	59.007	ENSGAFG00000008912	ncbp3	81	59.150	Gambusia_affinis
ENSG00000074356	NCBP3	99	53.988	ENSGACG00000020902	ncbp3	97	53.810	Gasterosteus_aculeatus
ENSG00000074356	NCBP3	100	79.936	ENSGAGG00000014490	NCBP3	98	79.837	Gopherus_agassizii
ENSG00000074356	NCBP3	99	100.000	ENSGGOG00000007496	NCBP3	100	100.000	Gorilla_gorilla
ENSG00000074356	NCBP3	98	94.224	ENSHGLG00000015839	NCBP3	98	94.389	Heterocephalus_glaber_female
ENSG00000074356	NCBP3	98	94.224	ENSHGLG00100007256	NCBP3	98	94.389	Heterocephalus_glaber_male
ENSG00000074356	NCBP3	99	52.471	ENSHCOG00000004161	ncbp3	98	53.125	Hippocampus_comes
ENSG00000074356	NCBP3	98	57.827	ENSIPUG00000024397	ncbp3	98	60.095	Ictalurus_punctatus
ENSG00000074356	NCBP3	72	100.000	ENSSTOG00000002101	NCBP3	100	96.725	Ictidomys_tridecemlineatus
ENSG00000074356	NCBP3	98	83.059	ENSJJAG00000000634	Ncbp3	98	82.730	Jaculus_jaculus
ENSG00000074356	NCBP3	98	52.562	ENSKMAG00000001932	ncbp3	98	53.744	Kryptolebias_marmoratus
ENSG00000074356	NCBP3	98	51.887	ENSLBEG00000006036	ncbp3	98	53.365	Labrus_bergylta
ENSG00000074356	NCBP3	98	51.603	ENSLBEG00000001558	-	98	52.256	Labrus_bergylta
ENSG00000074356	NCBP3	98	61.075	ENSLACG00000018791	NCBP3	98	60.390	Latimeria_chalumnae
ENSG00000074356	NCBP3	98	62.100	ENSLOCG00000006706	ncbp3	98	62.080	Lepisosteus_oculatus
ENSG00000074356	NCBP3	98	94.224	ENSLAFG00000002067	NCBP3	98	94.554	Loxodonta_africana
ENSG00000074356	NCBP3	100	98.548	ENSMFAG00000024176	NCBP3	100	98.548	Macaca_fascicularis
ENSG00000074356	NCBP3	100	98.548	ENSMMUG00000008556	NCBP3	100	98.548	Macaca_mulatta
ENSG00000074356	NCBP3	100	98.750	ENSMNEG00000041374	NCBP3	95	97.674	Macaca_nemestrina
ENSG00000074356	NCBP3	90	98.927	ENSMLEG00000034703	NCBP3	100	98.927	Mandrillus_leucophaeus
ENSG00000074356	NCBP3	99	52.983	ENSMAMG00000022461	ncbp3	98	53.324	Mastacembelus_armatus
ENSG00000074356	NCBP3	99	56.583	ENSMZEG00005027802	ncbp3	98	56.349	Maylandia_zebra
ENSG00000074356	NCBP3	94	79.181	ENSMGAG00000004685	NCBP3	98	81.294	Meleagris_gallopavo
ENSG00000074356	NCBP3	98	90.429	ENSMICG00000015798	NCBP3	98	90.594	Microcebus_murinus
ENSG00000074356	NCBP3	98	92.447	ENSMOCG00000016446	Ncbp3	98	92.611	Microtus_ochrogaster
ENSG00000074356	NCBP3	98	54.905	ENSMMOG00000012577	ncbp3	98	56.082	Mola_mola
ENSG00000074356	NCBP3	81	69.697	ENSMALG00000009173	ncbp3	98	53.385	Monopterus_albus
ENSG00000074356	NCBP3	98	93.564	MGP_CAROLIEiJ_G0016684	Ncbp3	98	93.729	Mus_caroli
ENSG00000074356	NCBP3	98	93.894	ENSMUSG00000020783	Ncbp3	98	94.059	Mus_musculus
ENSG00000074356	NCBP3	98	93.729	MGP_PahariEiJ_G0017817	Ncbp3	98	93.894	Mus_pahari
ENSG00000074356	NCBP3	98	93.894	MGP_SPRETEiJ_G0017521	Ncbp3	98	94.059	Mus_spretus
ENSG00000074356	NCBP3	100	95.000	ENSMPUG00000012357	NCBP3	95	93.355	Mustela_putorius_furo
ENSG00000074356	NCBP3	98	91.749	ENSMLUG00000017060	NCBP3	98	92.574	Myotis_lucifugus
ENSG00000074356	NCBP3	98	93.069	ENSNGAG00000020321	Ncbp3	98	93.234	Nannospalax_galili
ENSG00000074356	NCBP3	85	56.322	ENSNBRG00000017354	ncbp3	97	56.176	Neolamprologus_brichardi
ENSG00000074356	NCBP3	100	92.742	ENSNLEG00000017279	NCBP3	100	92.742	Nomascus_leucogenys
ENSG00000074356	NCBP3	67	81.967	ENSMEUG00000015701	-	76	81.967	Notamacropus_eugenii
ENSG00000074356	NCBP3	98	90.759	ENSOPRG00000016925	NCBP3	98	90.924	Ochotona_princeps
ENSG00000074356	NCBP3	98	94.719	ENSODEG00000016617	NCBP3	98	94.884	Octodon_degus
ENSG00000074356	NCBP3	99	51.143	ENSONIG00000007434	ncbp3	98	53.052	Oreochromis_niloticus
ENSG00000074356	NCBP3	100	78.080	ENSOANG00000010109	NCBP3	98	78.723	Ornithorhynchus_anatinus
ENSG00000074356	NCBP3	100	95.000	ENSOCUG00000008045	NCBP3	95	93.023	Oryctolagus_cuniculus
ENSG00000074356	NCBP3	98	53.566	ENSORLG00000013703	ncbp3	98	54.091	Oryzias_latipes
ENSG00000074356	NCBP3	98	53.707	ENSORLG00020011764	ncbp3	98	53.647	Oryzias_latipes_hni
ENSG00000074356	NCBP3	98	53.625	ENSORLG00015018733	ncbp3	98	54.173	Oryzias_latipes_hsok
ENSG00000074356	NCBP3	98	55.945	ENSOMEG00000017858	ncbp3	98	55.573	Oryzias_melastigma
ENSG00000074356	NCBP3	100	96.613	ENSOGAG00000008803	NCBP3	100	96.613	Otolemur_garnettii
ENSG00000074356	NCBP3	82	92.292	ENSOARG00000017750	NCBP3	97	92.886	Ovis_aries
ENSG00000074356	NCBP3	100	99.677	ENSPPAG00000030530	NCBP3	100	99.677	Pan_paniscus
ENSG00000074356	NCBP3	98	93.894	ENSPPRG00000022474	NCBP3	98	94.059	Panthera_pardus
ENSG00000074356	NCBP3	90	92.806	ENSPTIG00000009607	NCBP3	90	92.986	Panthera_tigris_altaica
ENSG00000074356	NCBP3	100	99.678	ENSPTRG00000008578	NCBP3	100	99.678	Pan_troglodytes
ENSG00000074356	NCBP3	100	98.871	ENSPANG00000024364	NCBP3	100	98.871	Papio_anubis
ENSG00000074356	NCBP3	98	51.796	ENSPKIG00000008466	ncbp3	98	53.631	Paramormyrops_kingsleyae
ENSG00000074356	NCBP3	72	96.154	ENSPSIG00000013732	NCBP3	96	77.344	Pelodiscus_sinensis
ENSG00000074356	NCBP3	99	51.045	ENSPMGG00000003344	ncbp3	98	52.067	Periophthalmus_magnuspinnatus
ENSG00000074356	NCBP3	98	92.586	ENSPEMG00000007746	Ncbp3	98	92.751	Peromyscus_maniculatus_bairdii
ENSG00000074356	NCBP3	100	78.459	ENSPCIG00000008605	NCBP3	98	78.435	Phascolarctos_cinereus
ENSG00000074356	NCBP3	88	53.409	ENSPFOG00000000721	ncbp3	96	55.960	Poecilia_formosa
ENSG00000074356	NCBP3	98	55.075	ENSPLAG00000015399	ncbp3	98	55.539	Poecilia_latipinna
ENSG00000074356	NCBP3	98	53.314	ENSPMEG00000000896	ncbp3	98	55.772	Poecilia_mexicana
ENSG00000074356	NCBP3	98	54.573	ENSPREG00000001681	ncbp3	98	56.241	Poecilia_reticulata
ENSG00000074356	NCBP3	100	100.000	ENSPPYG00000007823	NCBP3	95	99.169	Pongo_abelii
ENSG00000074356	NCBP3	100	88.226	ENSPCAG00000012614	NCBP3	98	88.614	Procavia_capensis
ENSG00000074356	NCBP3	100	96.129	ENSPCOG00000016793	NCBP3	100	96.129	Propithecus_coquereli
ENSG00000074356	NCBP3	96	87.291	ENSPVAG00000012746	NCBP3	98	87.458	Pteropus_vampyrus
ENSG00000074356	NCBP3	99	51.802	ENSPNYG00000022677	ncbp3	98	52.824	Pundamilia_nyererei
ENSG00000074356	NCBP3	98	56.305	ENSPNAG00000003219	ncbp3	98	58.480	Pygocentrus_nattereri
ENSG00000074356	NCBP3	98	93.234	ENSRNOG00000018550	Ncbp3	98	93.234	Rattus_norvegicus
ENSG00000074356	NCBP3	100	98.548	ENSRBIG00000033247	NCBP3	100	98.548	Rhinopithecus_bieti
ENSG00000074356	NCBP3	100	100.000	ENSRROG00000043833	NCBP3	100	98.548	Rhinopithecus_roxellana
ENSG00000074356	NCBP3	100	97.903	ENSSBOG00000023178	NCBP3	100	97.903	Saimiri_boliviensis_boliviensis
ENSG00000074356	NCBP3	72	96.154	ENSSHAG00000003466	NCBP3	97	77.419	Sarcophilus_harrisii
ENSG00000074356	NCBP3	100	58.480	ENSSFOG00015005808	ncbp3	98	58.595	Scleropages_formosus
ENSG00000074356	NCBP3	98	50.000	ENSSMAG00000010917	ncbp3	98	50.933	Scophthalmus_maximus
ENSG00000074356	NCBP3	99	56.744	ENSSDUG00000023402	ncbp3	98	57.686	Seriola_dumerili
ENSG00000074356	NCBP3	99	45.958	ENSSLDG00000000742	ncbp3	98	46.412	Seriola_lalandi_dorsalis
ENSG00000074356	NCBP3	98	84.488	ENSSARG00000006634	NCBP3	98	84.323	Sorex_araneus
ENSG00000074356	NCBP3	100	76.619	ENSSPUG00000002240	NCBP3	98	75.444	Sphenodon_punctatus
ENSG00000074356	NCBP3	99	53.258	ENSSPAG00000011223	ncbp3	98	55.172	Stegastes_partitus
ENSG00000074356	NCBP3	98	94.059	ENSSSCG00000017870	NCBP3	98	94.059	Sus_scrofa
ENSG00000074356	NCBP3	98	79.214	ENSTGUG00000005396	NCBP3	98	81.445	Taeniopygia_guttata
ENSG00000074356	NCBP3	99	53.427	ENSTRUG00000003769	ncbp3	98	55.189	Takifugu_rubripes
ENSG00000074356	NCBP3	99	53.467	ENSTNIG00000004776	ncbp3	98	54.658	Tetraodon_nigroviridis
ENSG00000074356	NCBP3	98	89.109	ENSTBEG00000006308	NCBP3	98	89.439	Tupaia_belangeri
ENSG00000074356	NCBP3	98	87.789	ENSTTRG00000005845	NCBP3	98	88.284	Tursiops_truncatus
ENSG00000074356	NCBP3	98	90.675	ENSUAMG00000014043	NCBP3	98	90.836	Ursus_americanus
ENSG00000074356	NCBP3	100	95.000	ENSUMAG00000007519	NCBP3	96	93.028	Ursus_maritimus
ENSG00000074356	NCBP3	100	95.000	ENSVVUG00000026079	NCBP3	95	89.203	Vulpes_vulpes
ENSG00000074356	NCBP3	100	62.166	ENSXETG00000012965	ncbp3	98	63.124	Xenopus_tropicalis
ENSG00000074356	NCBP3	99	51.142	ENSXCOG00000018393	ncbp3	99	52.761	Xiphophorus_couchianus
ENSG00000074356	NCBP3	98	52.782	ENSXMAG00000006849	ncbp3	98	55.789	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000340	RNA 7-methylguanosine cap binding	26382858.	IMP	Function
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003729	mRNA binding	26382858.	IDA	Function
GO:0005515	protein binding	22365833.26382858.	IPI	Function
GO:0005634	nucleus	26382858.	IDA	Component
GO:0005737	cytoplasm	26382858.	IDA	Component
GO:0006370	7-methylguanosine mRNA capping	-	IEA	Process
GO:0016607	nuclear speck	-	IDA	Component
GO:0034518	RNA cap binding complex	26382858.	TAS	Component
GO:0051028	mRNA transport	-	IEA	Process
GO:0051607	defense response to virus	26382858.	IMP	Process