EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000083444 (Gene tree)
Gene ID: 5351
Gene Symbol: PLOD1
Alias: LH1|LLH|PLOD
Full Name: procollagen-lysine,2-oxoglutarate 5-dioxygenase 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 41,338 bases
Position: chr1:11,934,205-11,975,542
Accession: 9081
RBP type: canonical RBP
Summary: Lysyl hydroxylase is a membrane-bound homodimeric protein localized to the cisternae of the endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VI have deficiencies in lysyl hydroxylase activity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000196061	2OG-FeII_Oxy	PF03171.20	9.3e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000196061	PLOD1-201	2940	XM_024447707	ENSP00000196061	727 (aa)	XP_024303475	Q02809
ENST00000429000	PLOD1-203	886	-	ENSP00000405372	283 (aa)	-	Q5JXB7
ENST00000465920	PLOD1-205	871	-	-	- (aa)	-	-
ENST00000481933	PLOD1-207	2339	-	-	- (aa)	-	-
ENST00000358133	PLOD1-202	819	-	-	- (aa)	-	-
ENST00000470133	PLOD1-206	362	-	-	- (aa)	-	-
ENST00000485046	PLOD1-208	991	-	-	- (aa)	-	-
ENST00000449038	PLOD1-204	762	-	ENSP00000414443	225 (aa)	-	Q5JXB8
ENST00000491536	PLOD1-209	639	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000083444's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00310	Lysine degradation	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000083444	Myocardial Infarction	4.0880173E-004	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000083444	rs2273291	1	11965296	A	Moyamoya disease	29273593	[NR]	1.32	Orphanet_2573
ENSG00000083444	rs11121845	1	11968598	T	Plateletcrit	27863252	[0.041-0.056] unit decrease	0.04850045	EFO_0007985
ENSG00000083444	rs11121845	1	11968598	T	Platelet count	27863252	[0.032-0.046] unit decrease	0.03911354	EFO_0004309
ENSG00000083444	rs72641011	1	11963443	A	Diastolic blood pressure x alcohol consumption interaction (2df test)	29912962			EFO_0006336\|EFO_0004329
ENSG00000083444	rs1208984	1	11935119	?	Eosinophil counts	30595370			EFO_0004842

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000083444's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000083444	PLOD1	99	65.975	ENSAPOG00000013081	plod1a	99	65.434	Acanthochromis_polyacanthus
ENSG00000083444	PLOD1	99	60.219	ENSAPOG00000013652	plod3	96	61.418	Acanthochromis_polyacanthus
ENSG00000083444	PLOD1	97	59.034	ENSAMEG00000013650	PLOD2	95	59.034	Ailuropoda_melanoleuca
ENSG00000083444	PLOD1	100	90.437	ENSAMEG00000009887	PLOD1	97	93.069	Ailuropoda_melanoleuca
ENSG00000083444	PLOD1	97	59.375	ENSAMEG00000002732	PLOD3	95	59.375	Ailuropoda_melanoleuca
ENSG00000083444	PLOD1	97	60.765	ENSACIG00000009256	plod3	96	60.765	Amphilophus_citrinellus
ENSG00000083444	PLOD1	94	59.038	ENSACIG00000018677	plod2	99	59.038	Amphilophus_citrinellus
ENSG00000083444	PLOD1	98	60.924	ENSACIG00000007846	plod1a	96	61.560	Amphilophus_citrinellus
ENSG00000083444	PLOD1	97	67.852	ENSAOCG00000018734	plod1a	99	68.389	Amphiprion_ocellaris
ENSG00000083444	PLOD1	99	60.768	ENSAOCG00000009132	plod3	96	61.986	Amphiprion_ocellaris
ENSG00000083444	PLOD1	97	67.283	ENSAPEG00000006235	plod1a	99	67.283	Amphiprion_percula
ENSG00000083444	PLOD1	99	60.631	ENSAPEG00000020103	plod3	96	61.844	Amphiprion_percula
ENSG00000083444	PLOD1	97	68.369	ENSATEG00000022077	plod1a	96	68.369	Anabas_testudineus
ENSG00000083444	PLOD1	99	76.033	ENSAPLG00000011324	PLOD1	97	77.086	Anas_platyrhynchos
ENSG00000083444	PLOD1	97	60.635	ENSAPLG00000011127	PLOD2	99	60.635	Anas_platyrhynchos
ENSG00000083444	PLOD1	97	60.606	ENSACAG00000006657	PLOD2	95	60.606	Anolis_carolinensis
ENSG00000083444	PLOD1	97	61.690	ENSACAG00000003968	PLOD3	96	61.690	Anolis_carolinensis
ENSG00000083444	PLOD1	98	60.423	ENSANAG00000030377	PLOD2	96	60.423	Aotus_nancymaae
ENSG00000083444	PLOD1	97	56.615	ENSANAG00000036204	PLOD3	95	56.615	Aotus_nancymaae
ENSG00000083444	PLOD1	96	96.291	ENSANAG00000026221	PLOD1	100	96.291	Aotus_nancymaae
ENSG00000083444	PLOD1	99	64.503	ENSACLG00000002498	plod1a	96	65.674	Astatotilapia_calliptera
ENSG00000083444	PLOD1	97	58.540	ENSACLG00000027422	plod2	96	58.540	Astatotilapia_calliptera
ENSG00000083444	PLOD1	99	54.195	ENSAMXG00000016685	plod3	97	55.148	Astyanax_mexicanus
ENSG00000083444	PLOD1	99	66.849	ENSAMXG00000014065	plod1a	96	67.943	Astyanax_mexicanus
ENSG00000083444	PLOD1	98	93.961	ENSBTAG00000002052	PLOD1	99	94.017	Bos_taurus
ENSG00000083444	PLOD1	98	60.282	ENSBTAG00000007331	PLOD2	96	60.282	Bos_taurus
ENSG00000083444	PLOD1	97	60.369	ENSBTAG00000000342	PLOD3	93	60.369	Bos_taurus
ENSG00000083444	PLOD1	98	60.423	ENSCJAG00000001578	PLOD2	98	58.978	Callithrix_jacchus
ENSG00000083444	PLOD1	100	96.424	ENSCJAG00000013459	PLOD1	100	96.424	Callithrix_jacchus
ENSG00000083444	PLOD1	97	59.659	ENSCJAG00000016006	PLOD3	95	59.659	Callithrix_jacchus
ENSG00000083444	PLOD1	97	59.577	ENSCAFG00000013860	PLOD3	96	59.577	Canis_familiaris
ENSG00000083444	PLOD1	98	93.952	ENSCAFG00000016522	PLOD1	100	93.948	Canis_familiaris
ENSG00000083444	PLOD1	97	58.953	ENSCAFG00000008101	PLOD2	95	58.953	Canis_familiaris
ENSG00000083444	PLOD1	97	60.740	ENSCAFG00020011739	PLOD2	97	60.597	Canis_lupus_dingo
ENSG00000083444	PLOD1	97	59.718	ENSCAFG00020013249	PLOD3	96	59.718	Canis_lupus_dingo
ENSG00000083444	PLOD1	98	93.952	ENSCAFG00020009101	PLOD1	100	93.948	Canis_lupus_dingo
ENSG00000083444	PLOD1	97	60.369	ENSCHIG00000015476	PLOD3	93	60.369	Capra_hircus
ENSG00000083444	PLOD1	98	60.563	ENSCHIG00000018266	PLOD2	96	60.882	Capra_hircus
ENSG00000083444	PLOD1	97	94.302	ENSCHIG00000025580	PLOD1	97	94.302	Capra_hircus
ENSG00000083444	PLOD1	92	94.039	ENSTSYG00000035536	PLOD1	100	94.039	Carlito_syrichta
ENSG00000083444	PLOD1	96	60.913	ENSTSYG00000007171	PLOD2	99	60.913	Carlito_syrichta
ENSG00000083444	PLOD1	95	66.228	ENSCAPG00000010686	PLOD2	91	66.228	Cavia_aperea
ENSG00000083444	PLOD1	97	55.446	ENSCPOG00000014514	PLOD2	99	55.728	Cavia_porcellus
ENSG00000083444	PLOD1	98	60.423	ENSCCAG00000025733	PLOD2	96	60.423	Cebus_capucinus
ENSG00000083444	PLOD1	97	59.801	ENSCCAG00000031443	PLOD3	95	59.801	Cebus_capucinus
ENSG00000083444	PLOD1	100	97.111	ENSCCAG00000024821	PLOD1	100	97.111	Cebus_capucinus
ENSG00000083444	PLOD1	98	60.563	ENSCATG00000041420	PLOD2	96	60.563	Cercocebus_atys
ENSG00000083444	PLOD1	97	59.801	ENSCATG00000038394	PLOD3	95	59.801	Cercocebus_atys
ENSG00000083444	PLOD1	99	93.407	ENSCATG00000017580	PLOD1	98	95.056	Cercocebus_atys
ENSG00000083444	PLOD1	97	59.801	ENSCLAG00000006817	PLOD3	95	59.801	Chinchilla_lanigera
ENSG00000083444	PLOD1	98	92.546	ENSCLAG00000013276	PLOD1	100	92.572	Chinchilla_lanigera
ENSG00000083444	PLOD1	97	60.426	ENSCLAG00000008696	PLOD2	95	60.426	Chinchilla_lanigera
ENSG00000083444	PLOD1	97	59.659	ENSCSAG00000018025	PLOD3	95	59.659	Chlorocebus_sabaeus
ENSG00000083444	PLOD1	99	58.056	ENSCSAG00000011365	PLOD2	96	58.824	Chlorocebus_sabaeus
ENSG00000083444	PLOD1	95	62.734	ENSCPBG00000010409	PLOD3	96	62.734	Chrysemys_picta_bellii
ENSG00000083444	PLOD1	98	77.528	ENSCPBG00000021958	PLOD1	97	77.904	Chrysemys_picta_bellii
ENSG00000083444	PLOD1	100	98.349	ENSCANG00000000277	PLOD1	100	98.349	Colobus_angolensis_palliatus
ENSG00000083444	PLOD1	97	59.801	ENSCANG00000042030	PLOD3	95	59.801	Colobus_angolensis_palliatus
ENSG00000083444	PLOD1	98	60.563	ENSCANG00000032726	PLOD2	96	60.563	Colobus_angolensis_palliatus
ENSG00000083444	PLOD1	97	59.091	ENSCGRG00001017088	Plod3	94	59.091	Cricetulus_griseus_chok1gshd
ENSG00000083444	PLOD1	98	60.449	ENSCGRG00001022906	Plod2	95	60.851	Cricetulus_griseus_chok1gshd
ENSG00000083444	PLOD1	96	57.692	ENSCGRG00000009240	Plod3	99	57.692	Cricetulus_griseus_crigri
ENSG00000083444	PLOD1	98	60.449	ENSCGRG00000001261	Plod2	98	60.851	Cricetulus_griseus_crigri
ENSG00000083444	PLOD1	99	65.522	ENSCVAG00000020899	plod1a	96	67.943	Cyprinodon_variegatus
ENSG00000083444	PLOD1	86	61.367	ENSCVAG00000015237	plod3	99	61.367	Cyprinodon_variegatus
ENSG00000083444	PLOD1	99	59.615	ENSDARG00000076317	plod3	98	60.393	Danio_rerio
ENSG00000083444	PLOD1	97	68.369	ENSDARG00000059746	plod1a	96	68.369	Danio_rerio
ENSG00000083444	PLOD1	99	57.793	ENSDARG00000011821	plod2	96	58.723	Danio_rerio
ENSG00000083444	PLOD1	96	92.308	ENSDNOG00000030750	PLOD1	100	91.209	Dasypus_novemcinctus
ENSG00000083444	PLOD1	97	57.260	ENSDNOG00000005149	PLOD2	96	57.260	Dasypus_novemcinctus
ENSG00000083444	PLOD1	97	60.455	ENSDORG00000003217	Plod2	99	60.770	Dipodomys_ordii
ENSG00000083444	PLOD1	97	87.394	ENSDORG00000008737	Plod1	99	87.553	Dipodomys_ordii
ENSG00000083444	PLOD1	98	44.073	FBgn0036147	Plod	98	44.134	Drosophila_melanogaster
ENSG00000083444	PLOD1	98	61.127	ENSEASG00005000164	PLOD2	96	61.127	Equus_asinus_asinus
ENSG00000083444	PLOD1	99	79.542	ENSEASG00005016643	PLOD1	97	81.092	Equus_asinus_asinus
ENSG00000083444	PLOD1	97	60.938	ENSEASG00005016919	PLOD3	95	60.938	Equus_asinus_asinus
ENSG00000083444	PLOD1	97	60.938	ENSECAG00000021913	PLOD3	94	60.938	Equus_caballus
ENSG00000083444	PLOD1	98	93.952	ENSECAG00000022842	PLOD1	100	93.948	Equus_caballus
ENSG00000083444	PLOD1	98	61.127	ENSECAG00000009297	PLOD2	96	61.127	Equus_caballus
ENSG00000083444	PLOD1	85	49.275	ENSEEUG00000015012	PLOD2	83	49.275	Erinaceus_europaeus
ENSG00000083444	PLOD1	98	94.374	ENSFCAG00000000074	PLOD1	100	94.360	Felis_catus
ENSG00000083444	PLOD1	97	60.426	ENSFCAG00000023549	PLOD2	95	60.426	Felis_catus
ENSG00000083444	PLOD1	97	59.091	ENSFCAG00000005798	PLOD3	95	59.091	Felis_catus
ENSG00000083444	PLOD1	97	76.945	ENSFALG00000010022	PLOD1	97	76.945	Ficedula_albicollis
ENSG00000083444	PLOD1	97	61.517	ENSFALG00000007086	PLOD2	94	61.517	Ficedula_albicollis
ENSG00000083444	PLOD1	96	92.011	ENSFDAG00000013861	PLOD1	100	92.011	Fukomys_damarensis
ENSG00000083444	PLOD1	97	60.227	ENSFDAG00000007784	PLOD3	95	60.227	Fukomys_damarensis
ENSG00000083444	PLOD1	89	58.234	ENSFDAG00000011434	PLOD2	100	58.234	Fukomys_damarensis
ENSG00000083444	PLOD1	73	64.561	ENSFHEG00000019833	plod3	79	64.561	Fundulus_heteroclitus
ENSG00000083444	PLOD1	100	63.847	ENSFHEG00000021014	plod1a	99	66.261	Fundulus_heteroclitus
ENSG00000083444	PLOD1	96	66.619	ENSGMOG00000003290	plod1a	100	66.619	Gadus_morhua
ENSG00000083444	PLOD1	98	61.290	ENSGALG00000006783	PLOD2	99	59.375	Gallus_gallus
ENSG00000083444	PLOD1	97	77.793	ENSGALG00000004531	PLOD1	97	77.793	Gallus_gallus
ENSG00000083444	PLOD1	99	66.211	ENSGAFG00000014860	plod1a	97	67.606	Gambusia_affinis
ENSG00000083444	PLOD1	99	58.459	ENSGAFG00000020388	plod3	99	64.738	Gambusia_affinis
ENSG00000083444	PLOD1	97	67.376	ENSGACG00000013243	plod1a	96	67.376	Gasterosteus_aculeatus
ENSG00000083444	PLOD1	98	77.560	ENSGAGG00000016382	PLOD1	97	72.727	Gopherus_agassizii
ENSG00000083444	PLOD1	97	59.517	ENSGGOG00000016700	PLOD3	95	59.517	Gorilla_gorilla
ENSG00000083444	PLOD1	100	99.450	ENSGGOG00000013645	PLOD1	100	99.450	Gorilla_gorilla
ENSG00000083444	PLOD1	98	60.563	ENSGGOG00000014284	PLOD2	96	60.563	Gorilla_gorilla
ENSG00000083444	PLOD1	97	60.795	ENSHBUG00000020042	plod1a	99	60.795	Haplochromis_burtoni
ENSG00000083444	PLOD1	97	58.540	ENSHBUG00000015944	plod2	99	59.905	Haplochromis_burtoni
ENSG00000083444	PLOD1	97	60.000	ENSHGLG00000019219	PLOD2	95	60.000	Heterocephalus_glaber_female
ENSG00000083444	PLOD1	98	59.972	ENSHGLG00000016800	PLOD3	95	60.227	Heterocephalus_glaber_female
ENSG00000083444	PLOD1	98	92.837	ENSHGLG00000011999	PLOD1	98	92.948	Heterocephalus_glaber_female
ENSG00000083444	PLOD1	98	59.972	ENSHGLG00100008805	PLOD3	95	60.227	Heterocephalus_glaber_male
ENSG00000083444	PLOD1	98	92.697	ENSHGLG00100012433	PLOD1	98	92.807	Heterocephalus_glaber_male
ENSG00000083444	PLOD1	97	59.858	ENSHGLG00100003295	PLOD2	95	59.858	Heterocephalus_glaber_male
ENSG00000083444	PLOD1	99	59.122	ENSHCOG00000009023	plod3	91	60.284	Hippocampus_comes
ENSG00000083444	PLOD1	100	58.242	ENSIPUG00000001033	plod2	96	59.291	Ictalurus_punctatus
ENSG00000083444	PLOD1	97	60.455	ENSSTOG00000025550	PLOD2	95	60.455	Ictidomys_tridecemlineatus
ENSG00000083444	PLOD1	97	59.801	ENSSTOG00000022109	PLOD3	95	59.801	Ictidomys_tridecemlineatus
ENSG00000083444	PLOD1	97	93.608	ENSSTOG00000009927	PLOD1	96	93.608	Ictidomys_tridecemlineatus
ENSG00000083444	PLOD1	96	60.684	ENSJJAG00000017235	Plod3	94	60.684	Jaculus_jaculus
ENSG00000083444	PLOD1	98	92.264	ENSJJAG00000013988	Plod1	100	92.297	Jaculus_jaculus
ENSG00000083444	PLOD1	97	60.597	ENSJJAG00000013305	Plod2	98	60.511	Jaculus_jaculus
ENSG00000083444	PLOD1	99	68.088	ENSLBEG00000015540	plod1a	98	69.757	Labrus_bergylta
ENSG00000083444	PLOD1	98	62.151	ENSLOCG00000014098	plod3	96	62.482	Lepisosteus_oculatus
ENSG00000083444	PLOD1	97	60.055	ENSLOCG00000007750	plod2	92	60.055	Lepisosteus_oculatus
ENSG00000083444	PLOD1	100	92.572	ENSLAFG00000000373	PLOD1	100	92.572	Loxodonta_africana
ENSG00000083444	PLOD1	97	59.659	ENSLAFG00000021710	PLOD3	95	59.659	Loxodonta_africana
ENSG00000083444	PLOD1	97	61.735	ENSLAFG00000001931	PLOD2	99	61.735	Loxodonta_africana
ENSG00000083444	PLOD1	98	60.563	ENSMFAG00000038516	PLOD2	98	58.934	Macaca_fascicularis
ENSG00000083444	PLOD1	100	98.074	ENSMFAG00000037610	PLOD1	99	95.592	Macaca_fascicularis
ENSG00000083444	PLOD1	97	59.801	ENSMFAG00000033241	PLOD3	95	59.801	Macaca_fascicularis
ENSG00000083444	PLOD1	97	59.801	ENSMMUG00000006949	PLOD3	95	59.801	Macaca_mulatta
ENSG00000083444	PLOD1	94	58.807	ENSMMUG00000011577	PLOD2	99	58.807	Macaca_mulatta
ENSG00000083444	PLOD1	100	98.074	ENSMMUG00000032249	PLOD1	86	98.074	Macaca_mulatta
ENSG00000083444	PLOD1	97	59.801	ENSMNEG00000036923	PLOD3	95	59.801	Macaca_nemestrina
ENSG00000083444	PLOD1	100	98.074	ENSMNEG00000038691	PLOD1	100	98.074	Macaca_nemestrina
ENSG00000083444	PLOD1	98	60.423	ENSMNEG00000029275	PLOD2	98	58.790	Macaca_nemestrina
ENSG00000083444	PLOD1	98	60.423	ENSMLEG00000032487	PLOD2	96	60.423	Mandrillus_leucophaeus
ENSG00000083444	PLOD1	97	59.801	ENSMLEG00000036735	PLOD3	95	59.801	Mandrillus_leucophaeus
ENSG00000083444	PLOD1	99	67.218	ENSMAMG00000014686	plod1a	96	68.652	Mastacembelus_armatus
ENSG00000083444	PLOD1	99	64.641	ENSMZEG00005006985	plod1a	96	65.816	Maylandia_zebra
ENSG00000083444	PLOD1	77	52.415	ENSMZEG00005019823	plod2	100	55.405	Maylandia_zebra
ENSG00000083444	PLOD1	97	60.284	ENSMZEG00005017645	plod2	96	60.284	Maylandia_zebra
ENSG00000083444	PLOD1	97	61.506	ENSMGAG00000006583	PLOD2	95	61.506	Meleagris_gallopavo
ENSG00000083444	PLOD1	98	77.279	ENSMGAG00000006085	PLOD1	97	77.715	Meleagris_gallopavo
ENSG00000083444	PLOD1	66	71.000	ENSMAUG00000014281	Plod3	100	71.000	Mesocricetus_auratus
ENSG00000083444	PLOD1	97	60.567	ENSMAUG00000003215	Plod2	95	60.567	Mesocricetus_auratus
ENSG00000083444	PLOD1	97	58.014	ENSMICG00000033937	-	95	58.014	Microcebus_murinus
ENSG00000083444	PLOD1	98	60.423	ENSMICG00000049252	PLOD2	96	60.423	Microcebus_murinus
ENSG00000083444	PLOD1	100	94.360	ENSMICG00000002720	PLOD1	100	94.360	Microcebus_murinus
ENSG00000083444	PLOD1	100	91.884	ENSMOCG00000012299	Plod1	100	91.884	Microtus_ochrogaster
ENSG00000083444	PLOD1	97	60.511	ENSMOCG00000001131	Plod3	95	60.511	Microtus_ochrogaster
ENSG00000083444	PLOD1	99	59.315	ENSMOCG00000014848	Plod2	96	60.028	Microtus_ochrogaster
ENSG00000083444	PLOD1	97	67.994	ENSMMOG00000013171	plod1a	99	67.994	Mola_mola
ENSG00000083444	PLOD1	97	58.741	ENSMMOG00000011128	plod3	94	58.741	Mola_mola
ENSG00000083444	PLOD1	98	85.914	ENSMODG00000010880	PLOD1	97	85.915	Monodelphis_domestica
ENSG00000083444	PLOD1	97	59.212	ENSMODG00000005017	PLOD3	99	59.212	Monodelphis_domestica
ENSG00000083444	PLOD1	99	61.012	ENSMODG00000021246	PLOD2	95	61.986	Monodelphis_domestica
ENSG00000083444	PLOD1	97	68.369	ENSMALG00000016161	plod1a	99	68.279	Monopterus_albus
ENSG00000083444	PLOD1	98	91.445	MGP_CAROLIEiJ_G0026786	Plod1	98	91.831	Mus_caroli
ENSG00000083444	PLOD1	99	60.137	ENSMUSG00000032374	Plod2	95	60.993	Mus_musculus
ENSG00000083444	PLOD1	97	59.718	ENSMUSG00000004846	Plod3	96	59.718	Mus_musculus
ENSG00000083444	PLOD1	98	91.445	ENSMUSG00000019055	Plod1	98	91.831	Mus_musculus
ENSG00000083444	PLOD1	98	91.152	MGP_PahariEiJ_G0029134	Plod1	98	91.408	Mus_pahari
ENSG00000083444	PLOD1	99	60.274	MGP_PahariEiJ_G0015394	Plod2	95	61.135	Mus_pahari
ENSG00000083444	PLOD1	97	60.141	MGP_PahariEiJ_G0024447	Plod3	95	60.141	Mus_pahari
ENSG00000083444	PLOD1	97	59.859	MGP_SPRETEiJ_G0028866	Plod3	96	59.859	Mus_spretus
ENSG00000083444	PLOD1	99	60.468	MGP_SPRETEiJ_G0033668	Plod2	95	61.135	Mus_spretus
ENSG00000083444	PLOD1	98	91.304	MGP_SPRETEiJ_G0027779	Plod1	98	91.690	Mus_spretus
ENSG00000083444	PLOD1	97	59.116	ENSMPUG00000011826	PLOD2	95	59.116	Mustela_putorius_furo
ENSG00000083444	PLOD1	87	59.683	ENSMPUG00000015891	PLOD3	91	59.683	Mustela_putorius_furo
ENSG00000083444	PLOD1	97	94.160	ENSMPUG00000016393	PLOD1	91	94.160	Mustela_putorius_furo
ENSG00000083444	PLOD1	97	93.162	ENSMLUG00000007292	PLOD1	94	93.162	Myotis_lucifugus
ENSG00000083444	PLOD1	97	59.155	ENSNGAG00000018568	Plod3	96	59.155	Nannospalax_galili
ENSG00000083444	PLOD1	50	92.329	ENSNGAG00000008701	-	100	92.329	Nannospalax_galili
ENSG00000083444	PLOD1	97	60.455	ENSNGAG00000000687	Plod2	99	60.171	Nannospalax_galili
ENSG00000083444	PLOD1	99	64.374	ENSNBRG00000005025	plod1a	96	65.674	Neolamprologus_brichardi
ENSG00000083444	PLOD1	97	59.886	ENSNBRG00000017408	plod2	99	59.886	Neolamprologus_brichardi
ENSG00000083444	PLOD1	93	58.667	ENSNLEG00000008234	PLOD3	94	58.667	Nomascus_leucogenys
ENSG00000083444	PLOD1	99	59.726	ENSNLEG00000005034	PLOD2	96	60.423	Nomascus_leucogenys
ENSG00000083444	PLOD1	90	61.441	ENSMEUG00000012969	PLOD2	86	61.441	Notamacropus_eugenii
ENSG00000083444	PLOD1	84	79.775	ENSMEUG00000015654	PLOD3	82	79.775	Notamacropus_eugenii
ENSG00000083444	PLOD1	96	85.755	ENSMEUG00000008093	PLOD1	100	85.755	Notamacropus_eugenii
ENSG00000083444	PLOD1	81	52.764	ENSOPRG00000006945	PLOD2	77	52.764	Ochotona_princeps
ENSG00000083444	PLOD1	96	91.441	ENSOPRG00000006783	PLOD1	100	91.441	Ochotona_princeps
ENSG00000083444	PLOD1	97	60.227	ENSODEG00000016528	PLOD3	94	60.227	Octodon_degus
ENSG00000083444	PLOD1	99	59.482	ENSODEG00000009443	PLOD2	96	60.597	Octodon_degus
ENSG00000083444	PLOD1	98	89.045	ENSODEG00000013340	PLOD1	98	88.592	Octodon_degus
ENSG00000083444	PLOD1	97	57.989	ENSONIG00000005883	plod2	96	57.989	Oreochromis_niloticus
ENSG00000083444	PLOD1	98	65.132	ENSONIG00000017978	-	97	65.957	Oreochromis_niloticus
ENSG00000083444	PLOD1	56	84.275	ENSOANG00000004585	-	95	84.275	Ornithorhynchus_anatinus
ENSG00000083444	PLOD1	75	57.102	ENSOCUG00000021812	PLOD3	92	57.102	Oryctolagus_cuniculus
ENSG00000083444	PLOD1	97	92.735	ENSOCUG00000007960	PLOD1	91	92.735	Oryctolagus_cuniculus
ENSG00000083444	PLOD1	98	57.221	ENSOCUG00000001461	PLOD2	95	57.873	Oryctolagus_cuniculus
ENSG00000083444	PLOD1	50	65.565	ENSORLG00000029631	plod3	99	65.565	Oryzias_latipes
ENSG00000083444	PLOD1	100	66.255	ENSORLG00000018904	plod1a	97	67.092	Oryzias_latipes
ENSG00000083444	PLOD1	99	60.110	ENSORLG00015001924	plod3	98	63.231	Oryzias_latipes_hsok
ENSG00000083444	PLOD1	100	66.118	ENSOMEG00000022732	plod1a	97	67.234	Oryzias_melastigma
ENSG00000083444	PLOD1	99	60.357	ENSOMEG00000006893	plod3	96	61.418	Oryzias_melastigma
ENSG00000083444	PLOD1	97	54.834	ENSOGAG00000009905	PLOD2	100	54.834	Otolemur_garnettii
ENSG00000083444	PLOD1	97	59.659	ENSOGAG00000031724	PLOD3	94	59.659	Otolemur_garnettii
ENSG00000083444	PLOD1	98	90.616	ENSOGAG00000005351	PLOD1	100	90.685	Otolemur_garnettii
ENSG00000083444	PLOD1	97	59.887	ENSOARG00000015057	PLOD3	94	59.887	Ovis_aries
ENSG00000083444	PLOD1	98	58.824	ENSOARG00000005685	PLOD2	87	58.824	Ovis_aries
ENSG00000083444	PLOD1	97	94.160	ENSOARG00000017960	PLOD1	100	94.160	Ovis_aries
ENSG00000083444	PLOD1	98	60.563	ENSPPAG00000039540	PLOD2	96	60.563	Pan_paniscus
ENSG00000083444	PLOD1	100	99.312	ENSPPAG00000034724	PLOD1	100	99.312	Pan_paniscus
ENSG00000083444	PLOD1	97	59.801	ENSPPAG00000038349	PLOD3	95	59.801	Pan_paniscus
ENSG00000083444	PLOD1	97	60.993	ENSPPRG00000012277	PLOD2	95	60.993	Panthera_pardus
ENSG00000083444	PLOD1	98	93.812	ENSPPRG00000007588	PLOD1	100	93.810	Panthera_pardus
ENSG00000083444	PLOD1	96	94.009	ENSPTIG00000020156	PLOD1	96	94.009	Panthera_tigris_altaica
ENSG00000083444	PLOD1	97	61.024	ENSPTIG00000018891	PLOD2	99	58.949	Panthera_tigris_altaica
ENSG00000083444	PLOD1	100	99.037	ENSPTRG00000000158	PLOD1	100	99.037	Pan_troglodytes
ENSG00000083444	PLOD1	97	59.801	ENSPTRG00000019524	PLOD3	95	59.801	Pan_troglodytes
ENSG00000083444	PLOD1	97	59.801	ENSPTRG00000051360	-	95	59.801	Pan_troglodytes
ENSG00000083444	PLOD1	98	60.563	ENSPTRG00000015494	PLOD2	96	60.563	Pan_troglodytes
ENSG00000083444	PLOD1	97	59.801	ENSPANG00000021830	PLOD3	95	59.801	Papio_anubis
ENSG00000083444	PLOD1	98	60.563	ENSPANG00000020900	PLOD2	98	58.934	Papio_anubis
ENSG00000083444	PLOD1	99	93.352	ENSPANG00000009766	PLOD1	99	93.352	Papio_anubis
ENSG00000083444	PLOD1	99	68.377	ENSPKIG00000013959	plod1a	96	69.362	Paramormyrops_kingsleyae
ENSG00000083444	PLOD1	99	57.909	ENSPKIG00000009566	plod2	99	60.322	Paramormyrops_kingsleyae
ENSG00000083444	PLOD1	98	78.011	ENSPSIG00000011107	PLOD1	97	78.501	Pelodiscus_sinensis
ENSG00000083444	PLOD1	100	91.747	ENSPEMG00000000181	Plod1	100	91.747	Peromyscus_maniculatus_bairdii
ENSG00000083444	PLOD1	97	60.085	ENSPEMG00000000016	Plod3	95	60.085	Peromyscus_maniculatus_bairdii
ENSG00000083444	PLOD1	96	58.726	ENSPEMG00000023460	Plod2	99	58.726	Peromyscus_maniculatus_bairdii
ENSG00000083444	PLOD1	99	59.504	ENSPMAG00000003203	-	96	60.369	Petromyzon_marinus
ENSG00000083444	PLOD1	97	62.411	ENSPCIG00000018522	PLOD2	95	62.411	Phascolarctos_cinereus
ENSG00000083444	PLOD1	97	59.296	ENSPCIG00000019207	PLOD3	93	59.296	Phascolarctos_cinereus
ENSG00000083444	PLOD1	98	86.192	ENSPCIG00000030260	PLOD1	97	86.197	Phascolarctos_cinereus
ENSG00000083444	PLOD1	99	66.301	ENSPFOG00000017414	plod1a	96	68.085	Poecilia_formosa
ENSG00000083444	PLOD1	99	58.597	ENSPLAG00000004494	plod3	96	59.574	Poecilia_latipinna
ENSG00000083444	PLOD1	99	66.712	ENSPLAG00000018953	plod1a	99	68.541	Poecilia_latipinna
ENSG00000083444	PLOD1	99	58.597	ENSPMEG00000001542	plod3	96	59.574	Poecilia_mexicana
ENSG00000083444	PLOD1	99	66.164	ENSPMEG00000021855	plod1a	96	67.943	Poecilia_mexicana
ENSG00000083444	PLOD1	99	65.887	ENSPREG00000008836	plod1a	95	67.618	Poecilia_reticulata
ENSG00000083444	PLOD1	50	62.857	ENSPPYG00000029800	-	100	62.857	Pongo_abelii
ENSG00000083444	PLOD1	100	99.037	ENSPPYG00000001874	PLOD1	100	99.037	Pongo_abelii
ENSG00000083444	PLOD1	97	59.801	ENSPPYG00000017444	PLOD3	95	59.801	Pongo_abelii
ENSG00000083444	PLOD1	97	59.375	ENSPCOG00000015483	PLOD3	95	59.375	Propithecus_coquereli
ENSG00000083444	PLOD1	100	94.911	ENSPCOG00000013522	PLOD1	100	94.911	Propithecus_coquereli
ENSG00000083444	PLOD1	96	56.553	ENSPVAG00000001241	PLOD3	99	56.553	Pteropus_vampyrus
ENSG00000083444	PLOD1	97	61.997	ENSPNYG00000000578	plod1a	99	61.997	Pundamilia_nyererei
ENSG00000083444	PLOD1	94	59.913	ENSPNYG00000006024	plod2	99	59.913	Pundamilia_nyererei
ENSG00000083444	PLOD1	98	68.671	ENSPNAG00000004781	plod1a	96	69.078	Pygocentrus_nattereri
ENSG00000083444	PLOD1	99	59.341	ENSPNAG00000021984	plod3	98	59.916	Pygocentrus_nattereri
ENSG00000083444	PLOD1	98	91.549	ENSRNOG00000007763	Plod1	98	91.690	Rattus_norvegicus
ENSG00000083444	PLOD1	99	60.055	ENSRNOG00000030183	Plod2	95	60.709	Rattus_norvegicus
ENSG00000083444	PLOD1	98	60.423	ENSRBIG00000042963	PLOD2	100	58.832	Rhinopithecus_bieti
ENSG00000083444	PLOD1	100	91.609	ENSRBIG00000035926	PLOD1	100	91.609	Rhinopithecus_bieti
ENSG00000083444	PLOD1	98	58.687	ENSRROG00000031649	PLOD2	96	58.687	Rhinopithecus_roxellana
ENSG00000083444	PLOD1	97	59.801	ENSRROG00000038379	PLOD3	95	59.801	Rhinopithecus_roxellana
ENSG00000083444	PLOD1	98	60.563	ENSSBOG00000030460	PLOD2	99	59.809	Saimiri_boliviensis_boliviensis
ENSG00000083444	PLOD1	97	59.943	ENSSBOG00000020136	PLOD3	95	59.943	Saimiri_boliviensis_boliviensis
ENSG00000083444	PLOD1	96	78.317	ENSSBOG00000021276	PLOD1	98	78.310	Saimiri_boliviensis_boliviensis
ENSG00000083444	PLOD1	96	85.957	ENSSHAG00000007375	PLOD1	95	85.977	Sarcophilus_harrisii
ENSG00000083444	PLOD1	97	62.411	ENSSHAG00000017470	PLOD2	98	60.606	Sarcophilus_harrisii
ENSG00000083444	PLOD1	98	58.989	ENSSHAG00000001739	PLOD3	94	59.155	Sarcophilus_harrisii
ENSG00000083444	PLOD1	100	59.781	ENSSFOG00015022468	plod3	96	60.709	Scleropages_formosus
ENSG00000083444	PLOD1	99	60.274	ENSSFOG00015014512	plod2	94	61.966	Scleropages_formosus
ENSG00000083444	PLOD1	99	60.606	ENSSFOG00015017276	plod3	96	61.354	Scleropages_formosus
ENSG00000083444	PLOD1	90	69.466	ENSSFOG00015010374	plod1a	99	69.466	Scleropages_formosus
ENSG00000083444	PLOD1	99	65.522	ENSSMAG00000011129	plod1a	96	66.809	Scophthalmus_maximus
ENSG00000083444	PLOD1	98	67.507	ENSSDUG00000002187	plod1a	96	68.227	Seriola_dumerili
ENSG00000083444	PLOD1	99	60.357	ENSSDUG00000002200	plod3	96	61.418	Seriola_dumerili
ENSG00000083444	PLOD1	97	66.435	ENSSLDG00000016960	plod1a	90	66.435	Seriola_lalandi_dorsalis
ENSG00000083444	PLOD1	71	47.573	ENSSLDG00000007569	plod3	100	43.774	Seriola_lalandi_dorsalis
ENSG00000083444	PLOD1	72	55.556	ENSSARG00000003690	PLOD2	72	47.896	Sorex_araneus
ENSG00000083444	PLOD1	97	60.795	ENSSSCG00000028879	PLOD3	95	60.795	Sus_scrofa
ENSG00000083444	PLOD1	97	60.851	ENSSSCG00000011689	PLOD2	100	59.132	Sus_scrofa
ENSG00000083444	PLOD1	98	93.680	ENSSSCG00000003433	PLOD1	98	93.935	Sus_scrofa
ENSG00000083444	PLOD1	97	63.404	ENSTGUG00000008767	PLOD2	99	63.404	Taeniopygia_guttata
ENSG00000083444	PLOD1	100	75.479	ENSTGUG00000002406	-	97	76.803	Taeniopygia_guttata
ENSG00000083444	PLOD1	99	66.160	ENSTRUG00000008466	plod1	97	67.660	Takifugu_rubripes
ENSG00000083444	PLOD1	70	60.429	ENSTBEG00000014615	PLOD3	100	60.429	Tupaia_belangeri
ENSG00000083444	PLOD1	91	68.844	ENSTBEG00000015790	PLOD2	92	68.844	Tupaia_belangeri
ENSG00000083444	PLOD1	52	96.471	ENSTBEG00000003672	-	52	96.471	Tupaia_belangeri
ENSG00000083444	PLOD1	98	92.556	ENSTTRG00000003503	PLOD1	98	92.807	Tursiops_truncatus
ENSG00000083444	PLOD1	97	59.801	ENSTTRG00000004781	PLOD3	95	59.801	Tursiops_truncatus
ENSG00000083444	PLOD1	99	56.731	ENSUAMG00000013690	PLOD3	97	57.546	Ursus_americanus
ENSG00000083444	PLOD1	97	57.610	ENSUAMG00000020858	PLOD2	97	57.610	Ursus_americanus
ENSG00000083444	PLOD1	98	94.233	ENSUAMG00000010387	PLOD1	100	94.223	Ursus_americanus
ENSG00000083444	PLOD1	99	92.244	ENSUMAG00000022265	PLOD1	98	92.978	Ursus_maritimus
ENSG00000083444	PLOD1	94	58.807	ENSUMAG00000012593	PLOD2	99	58.807	Ursus_maritimus
ENSG00000083444	PLOD1	70	51.946	ENSVPAG00000001811	-	69	51.946	Vicugna_pacos
ENSG00000083444	PLOD1	97	60.882	ENSVVUG00000008510	PLOD2	99	60.882	Vulpes_vulpes
ENSG00000083444	PLOD1	98	92.448	ENSVVUG00000028568	PLOD1	95	93.732	Vulpes_vulpes
ENSG00000083444	PLOD1	97	59.718	ENSVVUG00000023620	PLOD3	96	59.718	Vulpes_vulpes
ENSG00000083444	PLOD1	80	66.494	ENSXCOG00000002023	plod1a	97	66.209	Xiphophorus_couchianus
ENSG00000083444	PLOD1	99	65.663	ENSXMAG00000004495	plod1a	97	67.042	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001666	response to hypoxia	15174142.	IEP	Process
GO:0005506	iron ion binding	-	IEA	Function
GO:0005789	endoplasmic reticulum membrane	-	TAS	Component
GO:0006464	cellular protein modification process	1577494.	NAS	Process
GO:0006493	protein O-linked glycosylation	10934207.	IDA	Process
GO:0008475	procollagen-lysine 5-dioxygenase activity	21873635.	IBA	Function
GO:0008475	procollagen-lysine 5-dioxygenase activity	9724729.10934207.	IDA	Function
GO:0008475	procollagen-lysine 5-dioxygenase activity	8621606.	IMP	Function
GO:0008475	procollagen-lysine 5-dioxygenase activity	9582318.	ISS	Function
GO:0008544	epidermis development	8449506.	IMP	Process
GO:0008544	epidermis development	1577494.	TAS	Process
GO:0017185	peptidyl-lysine hydroxylation	21873635.	IBA	Process
GO:0017185	peptidyl-lysine hydroxylation	8621606.9724729.10934207.	IDA	Process
GO:0017185	peptidyl-lysine hydroxylation	9582318.	ISS	Process
GO:0030199	collagen fibril organization	21873635.	IBA	Process
GO:0030867	rough endoplasmic reticulum membrane	-	IEA	Component
GO:0031418	L-ascorbic acid binding	-	IEA	Function
GO:0032963	collagen metabolic process	21873635.	IBA	Process
GO:0033823	procollagen glucosyltransferase activity	10934207.	IDA	Function
GO:0042803	protein homodimerization activity	1577494.	TAS	Function
GO:0046947	hydroxylysine biosynthetic process	21873635.	IBA	Process
GO:0046947	hydroxylysine biosynthetic process	9724729.10934207.	IDA	Process
GO:0046947	hydroxylysine biosynthetic process	9582318.	ISS	Process
GO:0046947	hydroxylysine biosynthetic process	1577494.	TAS	Process
GO:0055114	oxidation-reduction process	1577494.	TAS	Process
GO:0070062	extracellular exosome	19056867.	HDA	Component
GO:1902494	catalytic complex	-	IEA	Component

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr1	11949889	Silent	novel	V95V	0.13
BLCA	chr1	11957889	Silent	novel	F263F	0.16
BLCA	chr1	11957896	Missense_Mutation	novel	G266S	0.41
BLCA	chr1	11960727	Missense_Mutation	NA	E353K	0.61
BLCA	chr1	11957177	Intron	novel		0.35
BLCA	chr1	11957163	Intron	novel		0.29
BRCA	chr1	11957002	Silent	rs567164584	N243N	0.13
BRCA	chr1	11970739	Missense_Mutation	NA	E609Q	0.58
BRCA	chr1	11970785	Missense_Mutation	rs760314787	T624M	0.23
BRCA	chr1	11970727	Nonsense_Mutation	novel	Q605*	0.21
BRCA	chr1	11974738	Missense_Mutation	rs377406897	T705M	0.36	2OG-FeII_Oxy
CESC	chr1	11949847	Silent	rs371574381	L81L	0.24
CESC	chr1	11967016	Silent	novel	I560I	0.14
CESC	chr1	11949791	Missense_Mutation	NA	D63N	0.3
CESC	chr1	11949775	Splice_Region	novel	A57A	0.39
CESC	chr1	11954863	Missense_Mutation	rs199990859	R205C	0.37
CESC	chr1	11948013	Silent	rs11553679	T38T	0.36
CESC	chr1	11944579	Intron	NA		0.14
CESC	chr1	11972693	Intron	novel		0.38
CHOL	chr1	11957858	Missense_Mutation	novel	L253P	0.3
COAD	chr1	11964257	Missense_Mutation	novel	A429T	0.11
COAD	chr1	11957876	Missense_Mutation	rs144226170	R259H	0.19
COAD	chr1	11949826	Silent	NA	G74G	0.33
COAD	chr1	11963581	Missense_Mutation	NA	A383S	0.39
COAD	chr1	11965506	Silent	NA	R499R	0.33
COAD	chr1	11956949	Missense_Mutation	NA	V226M	0.09
COAD	chr1	11964297	Missense_Mutation	rs199567720	R442H	0.13
COAD	chr1	11958596	Silent	NA	L308L	0.43
COAD	chr1	11972940	Silent	NA	H657H	0.3
COAD	chr1	11949890	Missense_Mutation	rs763494719	I96V	0.3
COAD	chr1	11964219	Missense_Mutation	rs138586136	S416L	0.13
COAD	chr1	11970700	Missense_Mutation	rs149654030	V596M	0.21
COAD	chr1	11963555	Missense_Mutation	NA	S374N	0.33
COAD	chr1	11954579	Intron	novel		0.35
COAD	chr1	11970817	Splice_Site	NA	X634_splice	0.42
ESCA	chr1	11948013	Silent	rs11553679	T38T	0.26
ESCA	chr1	11949817	Silent	rs769238622	S71S	0.15
ESCA	chr1	11952662	Missense_Mutation	novel	A169V	0.39
ESCA	chr1	11957002	Silent	rs567164584	N243N	0.33
GBM	chr1	11974745	Silent	novel	Y707Y	0.14
GBM	chr1	11944612	Intron	novel		0.32
GBM	chr1	11963599	Missense_Mutation	rs373520363	E389K	0.43
GBM	chr1	11972919	Missense_Mutation	novel	Q650H	0.42	2OG-FeII_Oxy
GBM	chr1	11949814	Silent	novel	T70T	0.1
HNSC	chr1	11956951	Silent	rs371007185	V226V	0.32
HNSC	chr1	11952694	Missense_Mutation	NA	Q180E	0.16
HNSC	chr1	11964670	Nonsense_Mutation	novel	S452*	0.43
HNSC	chr1	11957850	Missense_Mutation	novel	L250F	0.17
HNSC	chr1	11970801	Silent	novel	P629P	0.47
KIRC	chr1	11949869	Missense_Mutation	novel	A89P	0.08
KIRC	chr1	11949870	Frame_Shift_Ins	novel	*D90Lfs15**	0.08
KIRP	chr1	11934748	5'Flank	novel		0.36
KIRP	chr1	11970773	Missense_Mutation	novel	I620S	0.18
LAML	chr1	11960762	Frame_Shift_Del	novel	*G365Afs23**	0.12
LAML	chr1	11964753	Missense_Mutation	NA	D480N	0.37
LAML	chr1	11974786	Missense_Mutation	rs149161535	A721V	0.06	2OG-FeII_Oxy
LGG	chr1	11974702	Missense_Mutation	NA	R693M	0.09	2OG-FeII_Oxy
LGG	chr1	11956986	Missense_Mutation	novel	V238A	0.1
LGG	chr1	11965509	Silent	novel	H500H	0.44
LGG	chr1	11974785	Missense_Mutation	novel	A721T	0.44	2OG-FeII_Oxy
LIHC	chr1	11963585	Missense_Mutation	NA	D384A	0.26
LUAD	chr1	11956925	Missense_Mutation	rs372534520	V218L	0.12
LUAD	chr1	11965563	Missense_Mutation	novel	N518K	0.13
LUAD	chr1	11965489	Missense_Mutation	rs144007935	M494V	0.1
LUAD	chr1	11947995	Silent	novel	T32T	0.42
LUAD	chr1	11949814	Silent	novel	T70T	0.25
LUAD	chr1	11957144	Intron	novel		0.19
LUAD	chr1	11964240	Missense_Mutation	NA	S423I	0.19
LUAD	chr1	11960721	Missense_Mutation	novel	G351C	0.55
LUAD	chr1	11950464	Missense_Mutation	novel	R137K	0.09
LUSC	chr1	11956916	Splice_Site	novel	X215_splice	0.19
LUSC	chr1	11956983	Missense_Mutation	rs748111731	P237L	0.16
LUSC	chr1	11958540	Missense_Mutation	novel	V290F	0.13
LUSC	chr1	11974680	Missense_Mutation	novel	N686Y	0.27	2OG-FeII_Oxy
LUSC	chr1	11958607	Missense_Mutation	novel	H312P	0.16
LUSC	chr1	11949795	Missense_Mutation	novel	W64L	0.32
LUSC	chr1	11957880	Silent	NA	F260F	0.22
LUSC	chr1	11964686	Silent	NA	I457I	0.43
LUSC	chr1	11967069	Missense_Mutation	NA	Q578L	0.31
LUSC	chr1	11970709	Missense_Mutation	NA	I599V	0.49
LUSC	chr1	11966993	Missense_Mutation	NA	P553A	0.35
OV	chr1	11970814	Missense_Mutation	novel	R634W	0.27
OV	chr1	11949893	Missense_Mutation	novel	L97F	0.05
OV	chr1	11949895	Silent	novel	L97L	0.05
OV	chr1	11972995	Missense_Mutation	NA	E676Q	0.49	2OG-FeII_Oxy
OV	chr1	11974741	Missense_Mutation	novel	H706P	0.06	2OG-FeII_Oxy
OV	chr1	11958611	Nonsense_Mutation	novel	Y313*	0.18
OV	chr1	11970714	Missense_Mutation	novel	D600E	0.1
OV	chr1	11964223	Silent	NA	N417N	0.74
OV	chr1	11958605	Silent	NA	L311L	0.94
OV	chr1	11970739	Nonsense_Mutation	novel	E609*	0.59
OV	chr1	11956925	Missense_Mutation	rs372534520	V218M	0.44
PAAD	chr1	11944642	Intron	rs568319180		0.19
PAAD	chr1	11972896	Missense_Mutation	rs149425237	V643I	0.1	2OG-FeII_Oxy
PRAD	chr1	11957913	Silent	rs373471550	D271D	0.46
PRAD	chr1	11957874	Silent	rs753994916	P258P	0.38
PRAD	chr1	11960752	Missense_Mutation	novel	A361G	0.34
READ	chr1	11974825	3'UTR	novel		0.16
SKCM	chr1	11974805	Silent	rs140741046	P727P	0.59
SKCM	chr1	11974796	Silent	NA	F724F	0.4
SKCM	chr1	11948064	Silent	NA	I55I	0.11
SKCM	chr1	11957097	Intron	novel		0.32
SKCM	chr1	11944619	Intron	NA		0.38
SKCM	chr1	11952735	Splice_Region	novel	R193R	0.55
SKCM	chr1	11952736	Splice_Site	novel	X193_splice	0.55
SKCM	chr1	11965494	Silent	novel	F495F	0.22
SKCM	chr1	11948049	Silent	novel	F50F	0.12
SKCM	chr1	11972895	Silent	rs763454814	V642V	0.6
SKCM	chr1	11958635	Silent	NA	F321F	0.18
SKCM	chr1	11964231	Missense_Mutation	novel	G420E	0.29
SKCM	chr1	11960664	Nonsense_Mutation	novel	Q332*	0.41
SKCM	chr1	11957096	Intron	novel		0.15
SKCM	chr1	11967011	Missense_Mutation	rs576500420	P559S	0.2
SKCM	chr1	11957872	Missense_Mutation	NA	P258S	0.17
SKCM	chr1	11957182	Intron	novel		0.46
SKCM	chr1	11965551	Silent	NA	T514T	0.15
SKCM	chr1	11950430	Missense_Mutation	NA	F126L	0.08
SKCM	chr1	11950441	Silent	NA	E129E	0.15
SKCM	chr1	11967011	Missense_Mutation	rs576500420	P559S	0.5
SKCM	chr1	11974784	Silent	rs140513387	I720I	0.27
SKCM	chr1	11974665	Missense_Mutation	novel	R681W	0.43	2OG-FeII_Oxy
STAD	chr1	11965569	In_Frame_Del	novel	W521_P527del	0.11
STAD	chr1	11965564	Missense_Mutation	rs750991056	D519N	0.16
STAD	chr1	11958612	Missense_Mutation	novel	P314S	0.24
STAD	chr1	11964234	Missense_Mutation	NA	A421V	0.36
STAD	chr1	11950364	Missense_Mutation	rs141809154	V104M	0.28
STAD	chr1	11964753	Missense_Mutation	NA	D480N	0.35
STAD	chr1	11958556	Missense_Mutation	NA	E295G	0.11
STAD	chr1	11970693	Silent	rs758425988	Y593Y	0.24
STAD	chr1	11970801	Silent	novel	P629P	0.33
STAD	chr1	11974668	Missense_Mutation	NA	F682L	0.11	2OG-FeII_Oxy
STAD	chr1	11948026	Missense_Mutation	rs778603432	R43C	0.04
STAD	chr1	11964293	Missense_Mutation	rs11553676	R441W	0.27
THCA	chr1	11957144	Intron	novel		0.04
THYM	chr1	11958554	Silent	rs747668784	I294I	0.15
UCEC	chr1	11966307	Silent	novel	L547L	0.42
UCEC	chr1	11970683	Missense_Mutation	novel	Q590R	0.15
UCEC	chr1	11964677	Silent	novel	I454I	0.32
UCEC	chr1	11944618	Intron	rs534978828		0.41
UCEC	chr1	11949772	Splice_Site	NA	X57_splice	0.25
UCEC	chr1	11957924	Missense_Mutation	NA	R275H	0.38
UCEC	chr1	11966296	Missense_Mutation	NA	A544T	0.3
UCEC	chr1	11966995	Silent	rs778242162	P553P	0.14
UCEC	chr1	11967034	Silent	NA	C566C	0.42
UCEC	chr1	11970677	Missense_Mutation	rs755346019	R588H	0.54
UCEC	chr1	11974784	Silent	rs140513387	I720I	0.13
UCEC	chr1	11958641	Silent	novel	H323H	0.2
UCEC	chr1	11970733	Missense_Mutation	rs757393804	G607S	0.54
UCEC	chr1	11958554	Silent	rs747668784	I294I	0.33
UCEC	chr1	11964179	Missense_Mutation	rs773517731	V403I	0.3
UCEC	chr1	11974806	Nonstop_Mutation	novel	728Qext111	0.39
UCEC	chr1	11949774	Missense_Mutation	novel	A57V	0.36
UCEC	chr1	11958627	Nonsense_Mutation	rs121913550	R319*	0.3
UCEC	chr1	11964234	Missense_Mutation	NA	A421V	0.33
UCEC	chr1	11966315	Missense_Mutation	rs748526375	T550M	0.29
UCEC	chr1	11952689	Missense_Mutation	novel	S178N	0.35
UCEC	chr1	11963552	Missense_Mutation	novel	R373H	0.46
UCEC	chr1	11949906	Missense_Mutation	novel	S101I	0.45
UCEC	chr1	11960766	Missense_Mutation	rs367592901	A366T	0.5
UCEC	chr1	11950493	Missense_Mutation	novel	D147N	0.29
UCEC	chr1	11965564	Missense_Mutation	rs750991056	D519N	0.25
UCEC	chr1	11967039	Missense_Mutation	novel	E568A	0.41
UCEC	chr1	11970762	Silent	novel	L616L	0.39
UCEC	chr1	11970677	Missense_Mutation	rs755346019	R588H	0.31
UCEC	chr1	11948013	Silent	rs11553679	T38T	0.12
UCEC	chr1	11957115	Intron	novel		0.3
UCEC	chr1	11952641	Missense_Mutation	novel	P162H	0.33
UCEC	chr1	11970799	Missense_Mutation	novel	P629S	0.31
UCEC	chr1	11974931	3'UTR	novel		0.29
UCEC	chr1	11952712	Missense_Mutation	novel	I186F	0.21
UCEC	chr1	11948069	Splice_Site	novel	X56_splice	0.49
UCEC	chr1	11949868	Silent	novel	H88H	0.54

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	DEL	0.1153	0.00029523
CHOL	DEL	0.8056	3.3987e-23
DLBC	DEL	0.0833	0.011841
HNSC	DEL	0.1379	7.0766e-07
KIRC	DEL	0.1439	2.3538e-09
KIRP	DEL	0.1736	1.462e-09
LUAD	DEL	0.1434	0.0024765
LUSC	DEL	0.3613	2.5882e-07
MESO	DEL	0.3333	2.434e-07
READ	DEL	0.3879	2.1758e-10
TGCT	DEL	0.18	0.00046313
UCS	DEL	0.2857	0.0051125

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0066	Kaplan-Meier Survival Analysis
SARC	0.00081	Kaplan-Meier Survival Analysis
MESO	0.00029	Kaplan-Meier Survival Analysis
ACC	0.0015	Kaplan-Meier Survival Analysis
UCS	0.019	Kaplan-Meier Survival Analysis
HNSC	0.012	Kaplan-Meier Survival Analysis
KIRP	0.003	Kaplan-Meier Survival Analysis
COAD	0.017	Kaplan-Meier Survival Analysis
PAAD	0.0068	Kaplan-Meier Survival Analysis
PCPG	0.0068	Kaplan-Meier Survival Analysis
BLCA	0.00014	Kaplan-Meier Survival Analysis
CESC	0.00062	Kaplan-Meier Survival Analysis
LAML	0.0011	Kaplan-Meier Survival Analysis
KICH	0.024	Kaplan-Meier Survival Analysis
GBM	0.0093	Kaplan-Meier Survival Analysis
LIHC	0.002	Kaplan-Meier Survival Analysis
LUAD	0.021	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742