EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000084073 (Gene tree)
Gene ID: 10269
Gene Symbol: ZMPSTE24
Alias: FACE-1|Ste24p|STE24|HGPS|PRO1
Full Name: zinc metallopeptidase STE24
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 36,135 bases
Position: chr1:40,258,050-40,294,184
Accession: 12877
RBP type: non-canonical RBP
Summary: This gene encodes a member of the peptidase M48A family. The encoded protein is a zinc metalloproteinase involved in the two step post-translational proteolytic cleavage of carboxy terminal residues of farnesylated prelamin A to form mature lamin A. Mutations in this gene have been associated with mandibuloacral dysplasia and restrictive dermopathy. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000372759	ZMPSTE24-201	3108	-	ENSP00000361845	475 (aa)	-	O75844
ENST00000474142	ZMPSTE24-203	530	-	-	- (aa)	-	-
ENST00000472583	ZMPSTE24-202	537	-	-	- (aa)	-	-
ENST00000479131	ZMPSTE24-204	561	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000084073's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa00900	Terpenoid backbone biosynthesis	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000084073's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001889	liver development	-	IEA	Process
GO:0001942	hair follicle development	-	IEA	Process
GO:0003007	heart morphogenesis	-	IEA	Process
GO:0003229	ventricular cardiac muscle tissue development	-	IEA	Process
GO:0003231	cardiac ventricle development	-	IEA	Process
GO:0003417	growth plate cartilage development	-	IEA	Process
GO:0003690	double-stranded DNA binding	-	IEA	Function
GO:0004222	metalloendopeptidase activity	21873635.	IBA	Function
GO:0005515	protein binding	23539603.28169297.	IPI	Function
GO:0005637	nuclear inner membrane	-	IEA	Component
GO:0006281	DNA repair	-	IEA	Process
GO:0006508	proteolysis	10373325.	TAS	Process
GO:0006925	inflammatory cell apoptotic process	-	IEA	Process
GO:0006998	nuclear envelope organization	-	IEA	Process
GO:0007628	adult walking behavior	-	IEA	Process
GO:0008235	metalloexopeptidase activity	10373325.	TAS	Function
GO:0008340	determination of adult lifespan	-	IEA	Process
GO:0008360	regulation of cell shape	-	IEA	Process
GO:0010506	regulation of autophagy	-	IEA	Process
GO:0010906	regulation of glucose metabolic process	-	IEA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0019216	regulation of lipid metabolic process	-	IEA	Process
GO:0030176	integral component of endoplasmic reticulum membrane	21873635.	IBA	Component
GO:0030282	bone mineralization	-	IEA	Process
GO:0030327	prenylated protein catabolic process	-	IEA	Process
GO:0030500	regulation of bone mineralization	-	IEA	Process
GO:0032006	regulation of TOR signaling	-	IEA	Process
GO:0032350	regulation of hormone metabolic process	-	IEA	Process
GO:0032991	protein-containing complex	28246125.	IDA	Component
GO:0035264	multicellular organism growth	-	IEA	Process
GO:0040014	regulation of multicellular organism growth	-	IEA	Process
GO:0043007	maintenance of rDNA	-	IEA	Process
GO:0043516	regulation of DNA damage response, signal transduction by p53 class mediator	-	IEA	Process
GO:0043979	histone H2B-K5 acetylation	-	IEA	Process
GO:0044029	hypomethylation of CpG island	-	IEA	Process
GO:0044255	cellular lipid metabolic process	-	IEA	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0048145	regulation of fibroblast proliferation	-	IEA	Process
GO:0048538	thymus development	-	IEA	Process
GO:0048739	cardiac muscle fiber development	-	IEA	Process
GO:0050688	regulation of defense response to virus	28246125.	IDA	Process
GO:0050905	neuromuscular process	-	IEA	Process
GO:0060307	regulation of ventricular cardiac muscle cell membrane repolarization	-	IEA	Process
GO:0060993	kidney morphogenesis	-	IEA	Process
GO:0061337	cardiac conduction	-	IEA	Process
GO:0061762	CAMKK-AMPK signaling cascade	-	IEA	Process
GO:0070062	extracellular exosome	19056867.	HDA	Component
GO:0070302	regulation of stress-activated protein kinase signaling cascade	-	IEA	Process
GO:0071480	cellular response to gamma radiation	-	IEA	Process
GO:0071586	CAAX-box protein processing	21873635.	IBA	Process
GO:0072423	response to DNA damage checkpoint signaling	-	IEA	Process
GO:1903025	regulation of RNA polymerase II regulatory region sequence-specific DNA binding	-	IEA	Process
GO:1903463	regulation of mitotic cell cycle DNA replication	-	IEA	Process
GO:1903799	negative regulation of production of miRNAs involved in gene silencing by miRNA	-	IEA	Process
GO:1990036	calcium ion import into sarcoplasmic reticulum	-	IEA	Process
GO:1990164	histone H2A phosphorylation	-	IEA	Process
GO:2000618	regulation of histone H4-K16 acetylation	-	IEA	Process
GO:2000730	regulation of termination of RNA polymerase I transcription	-	IEA	Process
GO:2000772	regulation of cellular senescence	-	IEA	Process