EuRBPDB

Description

Ensembl ID: ENSG00000084652 (Gene tree)
Gene ID: 200081
Gene Symbol: TXLNA
Alias: DKFZp451J0118
Full Name: taxilin alpha
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 18,600 bases
Position: chr1:32,179,686-32,198,285
Accession: 30685
RBP type: non-canonical RBP
Summary: (Taxilin Alpha) is a Protein Coding gene. Diseases associated with TXLNA include B-Cell Growth Factor and Inclusion Conjunctivitis. Among its related pathways are Cytokine Signaling in Immune system and Innate Immune System. Gene Ontology (GO) annotations related to this gene include cytokine activity and high molecular weight B cell growth factor receptor binding. An important paralog of this gene is TXLNG.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000373610	TXLNA-202	4854	XM_011540931	ENSP00000362712	546 (aa)	XP_011539233	P40222
ENST00000373609	TXLNA-201	5012	XM_017000561	ENSP00000362711	546 (aa)	XP_016856050	P40222

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000084652	TXLNA	100	88.530	ENSMUSG00000053841	Txlna	100	89.226	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005125	cytokine activity	8327514.	NAS	Function
GO:0005515	protein binding	21903422.25416956.26638075.	IPI	Function
GO:0005576	extracellular region	8327514.	NAS	Component
GO:0005737	cytoplasm	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006887	exocytosis	-	IEA	Process
GO:0008283	cell proliferation	8327514.	NAS	Process
GO:0010469	regulation of signaling receptor activity	-	IEA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0019221	cytokine-mediated signaling pathway	-	TAS	Process
GO:0019905	syntaxin binding	-	IEA	Function
GO:0030372	high molecular weight B cell growth factor receptor binding	8327514.	NAS	Function
GO:0042113	B cell activation	-	IEA	Process