EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000084674 (Gene tree)
Gene ID: 338
Gene Symbol: APOB
Alias: N
Full Name: apolipoprotein B
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 44,856 bases
Position: chr2:20,999,218-21,044,073
Accession: 603
RBP type: non-canonical RBP
Summary: This gene product is the main apolipoprotein of chylomicrons and low density lipoproteins. It occurs in plasma as two main isoforms, apoB-48 and apoB-100: the former is synthesized exclusively in the gut and the latter in the liver. The intestinal and the hepatic forms of apoB are encoded by a single gene from a single, very long mRNA. The two isoforms share a common N-terminal sequence. The shorter apoB-48 protein is produced after RNA editing of the apoB-100 transcript at residue 2180 (CAA->UAA), resulting in the creation of a stop codon, and early translation termination. Mutations in this gene or its regulatory region cause hypobetalipoproteinemia, normotriglyceridemic hypobetalipoproteinemia, and hypercholesterolemia due to ligand-defective apoB, diseases affecting plasma cholesterol and apoB levels. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
31080349	Curcumin modulates the apolipoprotein B mRNA editing by coordinating the expression of cytidine deamination to uridine editosome components in primary mouse hepatocytes.	Korean J Physiol Pharmacol	2019 May	He P	doi: 10.4196/kjpp.2019.23.3.181
7782342	apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, is a novel RNA-binding protein.	J Biol Chem	1995 Jun 16	Anant S	-
25585043	Re-editing the paradigm of Cytidine (C) to Uridine (U) RNA editing.	RNA Biol	2014	Fossat N	doi: 10.1080/15476286.2014.996054.
9274872	A cytidine deaminase expressed in the post-infective L3 stage of the filarial nematode, Brugia pahangi, has a novel RNA-binding activity.	Mol Biochem Parasitol	1997 Sep	Anant S	-
7972084	Molecular cloning of cDNA for double-stranded RNA adenosine deaminase, a candidate enzyme for nuclear RNA editing.	Proc Natl Acad Sci U S A	1994 Nov 22	Kim U	-
7782343	Mutagenesis of apobec-1, the catalytic subunit of the mammalian apolipoprotein B mRNA editing enzyme, reveals distinct domains that mediate cytosine nucleoside deaminase, RNA binding, and RNA editing activity.	J Biol Chem	1995 Jun 16	MacGinnitie AJ	-
11870221	The editosome for cytidine to uridine mRNA editing has a native complexity of 27S: identification of intracellular domains containing active and inactive editing factors.	J Cell Sci	2002 Mar 1	Sowden MP	-
11698249	ARCD-1, an apobec-1-related cytidine deaminase, exerts a dominant negative effect on C to U RNA editing.	Am J Physiol Cell Physiol	2001 Dec	Anant S	-
11571303	Mutagenesis of apobec-1 complementation factor reveals distinct domains that modulate RNA binding, protein-protein interaction with apobec-1, and complementation of C to U RNA-editing activity.	J Biol Chem	2001 Dec 7	Blanc V	-
11577082	Novel role for RNA-binding protein CUGBP2 in mammalian RNA editing. CUGBP2 modulates C to U editing of apolipoprotein B mRNA by interacting with apobec-1 and ACF, the apobec-1 complementation factor.	J Biol Chem	2001 Dec 14	Anant S	-
21971522	Translational control mechanisms in metabolic regulation: critical role of RNA binding proteins, microRNAs, and cytoplasmic RNA granules.	Am J Physiol Endocrinol Metab	2011 Dec	Adeli K	doi: 10.1152/ajpendo.00399.2011
20541607	Metabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytes.	Biochim Biophys Acta	2010 Nov	Galloway CA	doi: 10.1016/j.bbadis.2010.06.003
20406809	Apobec-1 complementation factor modulates liver regeneration by post-transcriptional regulation of interleukin-6 mRNA stability.	J Biol Chem	2010 Jun 18	Blanc V	doi: 10.1074/jbc.M110.115147
16920700	ApoB mRNA editing is mediated by a coordinated modulation of multiple apoB mRNA editing enzyme components.	Am J Physiol Gastrointest Liver Physiol	2007 Jan	Chen Z	-
16156669	Insulin-mediated suppression of apolipoprotein B mRNA translation requires the 5' UTR and is characterized by decreased binding of an insulin-sensitive 110-kDa 5' UTR RNA-binding protein.	Biochemistry	2005 Sep 20	Sidiropoulos KG	-
9822632	Secondary structure for the apolipoprotein B mRNA editing site. Au-binding proteins interact with a stem loop.	J Biol Chem	1998 Nov 27	Richardson N	-
9671452	A sequence-specific RNA-binding protein complements apobec-1 To edit apolipoprotein B mRNA.	Mol Cell Biol	1998 Aug	Mehta A	-
9346911	Partial characterization of the auxiliary factors involved in apolipoprotein B mRNA editing through APOBEC-1 affinity chromatography.	J Biol Chem	1997 Oct 31	Yang Y	-
8463271	Extract-specific heterogeneity in high-order complexes containing apolipoprotein B mRNA editing activity and RNA-binding proteins.	J Biol Chem	1993 Apr 5	Harris SG	-
7736571	Evolutionary origins of apoB mRNA editing: catalysis by a cytidine deaminase that has acquired a novel RNA-binding motif at its active site.	Cell	1995 Apr 21	Navaratnam N	-
12896982	A novel nuclear localization signal in the auxiliary domain of apobec-1 complementation factor regulates nucleocytoplasmic import and shuttling.	J Biol Chem	2003 Oct 17	Blanc V	-
12881431	The apolipoprotein B mRNA editing complex performs a multifunctional cycle and suppresses nonsense-mediated decay.	EMBO J	2003 Aug 1	Chester A	-
11863358	An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.	Genomics	2002 Mar	Jarmuz A	-
11134005	Identification of GRY-RBP as an apolipoprotein B RNA-binding protein that interacts with both apobec-1 and apobec-1 complementation factor to modulate C to U editing.	J Biol Chem	2001 Mar 30	Blanc V	-
10669759	Molecular cloning of apobec-1 complementation factor, a novel RNA-binding protein involved in the editing of apolipoprotein B mRNA.	Mol Cell Biol	2000 Mar	Mehta A	-
10688645	An AU-rich sequence element (UUUN[A/U]U) downstream of the edited C in apolipoprotein B mRNA is a high-affinity binding site for Apobec-1: binding of Apobec-1 to this motif in the 3' untranslated region of c-myc increases mRNA stability.	Mol Cell Biol	2000 Mar	Anant S	-
16887808	The anti-HIV-1 editing enzyme APOBEC3G binds HIV-1 RNA and messenger RNAs that shuttle between polysomes and stress granules.	J Biol Chem	2006 Sep 29	Kozak SL	-
16055734	Targeted deletion of the murine apobec-1 complementation factor (acf) gene results in embryonic lethality.	Mol Cell Biol	2005 Aug	Blanc V	-
15157107	Translational control of apolipoprotein B mRNA: regulation via cis elements in the 5' and 3' untranslated regions.	Biochemistry	2004 Jun 1	Pontrelli L	-
14570923	Identification of novel alternative splice variants of APOBEC-1 complementation factor with different capacities to support apolipoprotein B mRNA editing.	J Biol Chem	2004 Jan 2	Sowden MP	-
22923694	Transgenerational epigenetic effects of the Apobec1 cytidine deaminase deficiency on testicular germ cell tumor susceptibility and embryonic viability.	Proc Natl Acad Sci U S A	2012 Oct 9	Nelson VR	doi: 10.1073/pnas.1207169109
17288985	Translational control of apolipoprotein B mRNA via insulin and the protein kinase C signaling cascades: evidence for modulation of RNA-protein interactions at the 5'UTR.	Arch Biochem Biophys	2007 Mar 1	Sidiropoulos KG	-
27665711	The RNA-binding protein vigilin regulates VLDL secretion through modulation of Apob mRNA translation.	Nat Commun	2016 Sep 26	Mobin MB	doi: 10.1038/ncomms12848.
15947549	Proteomic analysis of differentially expressed proteins between metastatic and non-metastatic human colorectal carcinoma cell lines.	Eur J Gastroenterol Hepatol	2005 Jul	Ying-Tao Z	-
2216773	A 40 kilodalton rat liver nuclear protein binds specifically to apolipoprotein B mRNA around the RNA editing site.	Nucleic Acids Res	1990 Oct 11	Lau PP	-
8999813	Cloning of an Apobec-1-binding protein that also interacts with apolipoprotein B mRNA and evidence for its involvement in RNA editing.	J Biol Chem	1997 Jan 17	Lau PP	-
8086446	Only cytidines 5' of the apolipoprotein B mRNA mooring sequence are edited.	Biochim Biophys Acta	1994 Sep 13	Backus JW	-
17848425	ISIS 301012 gene therapy for hypercholesterolemia: sense, antisense, or nonsense?	Ann Pharmacother	2007 Oct	Ito MK	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000233242	APOB-201	14121	-	ENSP00000233242	4563 (aa)	-	P04114
ENST00000399256	APOB-202	3128	-	ENSP00000382200	828 (aa)	-	A8MUN2

Gene Model

Click here to download ENSG00000084674's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04975	Fat digestion and absorption	KEGG
hsa04977	Vitamin digestion and absorption	KEGG
hsa04979	Cholesterol metabolism	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000084674	Cholesterol, HDL	3.395e-006	19060910
ENSG00000084674	Cholesterol, HDL	4.78e-006	19060910
ENSG00000084674	Cholesterol, LDL	2.986e-011	19060910
ENSG00000084674	Cholesterol, LDL	2.283e-007	19060910
ENSG00000084674	Cholesterol, LDL	2.603e-007	19060910
ENSG00000084674	Cholesterol, LDL	9.044e-005	19060910
ENSG00000084674	Cholesterol, LDL	1.124e-006	19060910
ENSG00000084674	Cholesterol, LDL	2.031e-007	19060910
ENSG00000084674	Cholesterol, LDL	2.177e-006	19060910
ENSG00000084674	Cholesterol, LDL	9.327e-008	19060910
ENSG00000084674	Triglycerides	2.012e-008	19060910
ENSG00000084674	Triglycerides	3.363e-008	19060910
ENSG00000084674	Cholesterol, LDL	3.3030000E-005	-
ENSG00000084674	Testosterone	4.8330000E-005	-
ENSG00000084674	Testosterone	4.4650000E-005	-
ENSG00000084674	Testosterone	2.5690000E-005	-
ENSG00000084674	oxidized low density lipoprotein	1.0510000E-011	-
ENSG00000084674	oxidized low density lipoprotein	3.8280000E-008	-
ENSG00000084674	oxidized low density lipoprotein	7.9440000E-008	-
ENSG00000084674	oxidized low density lipoprotein	5.5500000E-030	-
ENSG00000084674	oxidized low density lipoprotein	6.1670000E-031	-
ENSG00000084674	oxidized low density lipoprotein	2.2740000E-012	-
ENSG00000084674	oxidized low density lipoprotein	1.0620000E-005	-
ENSG00000084674	oxidized low density lipoprotein	8.8510000E-006	-
ENSG00000084674	oxidized low density lipoprotein	7.7140000E-026	-
ENSG00000084674	Metabolic Syndrome X	1E-10	22399527
ENSG00000084674	Cholesterol, LDL	1E-9	18262040
ENSG00000084674	Cholesterol, LDL	2E-63	25961943
ENSG00000084674	Atrial Fibrillation	5E-21	27790247
ENSG00000084674	Blood Pressure	5E-21	27790247
ENSG00000084674	Cholesterol	5E-21	27790247
ENSG00000084674	Coronary Disease	5E-21	27790247
ENSG00000084674	Diabetes Mellitus	5E-21	27790247
ENSG00000084674	Electrocardiography	5E-21	27790247
ENSG00000084674	Glucose	5E-21	27790247
ENSG00000084674	Heart Failure	5E-21	27790247
ENSG00000084674	Hematocrit	5E-21	27790247
ENSG00000084674	Cholesterol, HDL	5E-21	27790247
ENSG00000084674	Mortality	5E-21	27790247
ENSG00000084674	Neoplasms	5E-21	27790247
ENSG00000084674	Triglycerides	5E-21	27790247
ENSG00000084674	Body Mass Index	5E-21	27790247
ENSG00000084674	Stroke	5E-21	27790247
ENSG00000084674	Triglycerides	7E-7	17463246
ENSG00000084674	Cholesterol, LDL	5E-29	19060906
ENSG00000084674	Cholesterol	7E-6	26582766
ENSG00000084674	1-Alkyl-2-acetylglycerophosphocholine Esterase	2E-7	23118302
ENSG00000084674	Cholesterol	3E-139	24097068
ENSG00000084674	Lipids	5E-42	19936222
ENSG00000084674	Lipids	4E-10	19936222
ENSG00000084674	Lipids	6E-25	19936222
ENSG00000084674	Lipids	2E-17	19936222
ENSG00000084674	Cholesterol, LDL	6E-22	18193043
ENSG00000084674	Triglycerides	2E-8	19060910
ENSG00000084674	Cholesterol	5E-54	25961943
ENSG00000084674	Cholesterol, LDL	4E-114	20686565
ENSG00000084674	Lipoproteins	6E-19	27005778
ENSG00000084674	Metabolism	6E-19	27005778
ENSG00000084674	Hydroxymethylglutaryl CoA Reductases	8E-6	20339536
ENSG00000084674	Lipids	2E-9	19936222
ENSG00000084674	Lipids	4E-64	19936222
ENSG00000084674	Lipids	9E-56	19936222
ENSG00000084674	Cholesterol, LDL	3E-6	26582766
ENSG00000084674	Cholesterol, HDL	1E-30	20686565
ENSG00000084674	Triglycerides	2E-7	18193044
ENSG00000084674	Lipids	4E-8	23726366
ENSG00000084674	Blood Pressure	3E-25	27790247
ENSG00000084674	Cholesterol	3E-25	27790247
ENSG00000084674	Electrocardiography	3E-25	27790247
ENSG00000084674	Glucose	3E-25	27790247
ENSG00000084674	Hematocrit	3E-25	27790247
ENSG00000084674	Cholesterol, HDL	3E-25	27790247
ENSG00000084674	Triglycerides	3E-25	27790247
ENSG00000084674	Body Mass Index	3E-25	27790247
ENSG00000084674	Cholesterol, LDL	1E-182	24097068
ENSG00000084674	Cholesterol, LDL	4E-17	19060911
ENSG00000084674	Cholesterol	9E-23	19060911
ENSG00000084674	Cholesterol, LDL	3E-11	19060910
ENSG00000084674	Vascular Calcification	1E-13	22916037
ENSG00000084674	Cholesterol, LDL	1E-21	18193044
ENSG00000084674	Cholesterol, LDL	3E-47	23247145
ENSG00000084674	Cholesterol	4E-96	20686565
ENSG00000084674	Triglycerides	1E-45	20686565
ENSG00000084674	Cholesterol, LDL	8E-15	21943158
ENSG00000084674	Cholesterol, LDL	2E-20	20864672
ENSG00000084674	Cholesterol, HDL	7E-21	25961943

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000084674	rs1367117	2	21041028	A	LDL cholesterol	24097068	[NR] unit increase	0.119	EFO_0004611
ENSG00000084674	rs693	2	21009323	A	LDL cholesterol	18193044	[0.10-0.14] unit increase	0.12	EFO_0004611
ENSG00000084674	rs2678379	2	21003688	A	HDL cholesterol	25961943	[0.051-0.079] s.d. increase	0.065	EFO_0004612
ENSG00000084674	rs6413458	2	21008720	T	Lipoprotein-associated phospholipase A2 activity and mass	23118302	[0.0088-0.0708] ng/ml decrease	0.0398	EFO_0004746
ENSG00000084674	rs676210	2	21008652	G	LDL (oxidized)	23247145	U/L increase	10.5	EFO_0004611
ENSG00000084674	rs12713956	2	21018633	G	LDL cholesterol	23726366	[NR] unit decrease	4.86	EFO_0004529
ENSG00000084674	rs1367117	2	21041028	?	Lipid metabolism phenotypes	19936222	[NR] unit increase	3.916	EFO_0004529
ENSG00000084674	rs1367117	2	21041028	?	Lipid metabolism phenotypes	19936222	[NR] unit increase	4.027	EFO_0004529
ENSG00000084674	rs676210	2	21008652	?	Lipid metabolism phenotypes	19936222	[NR] unit decrease	0.047	EFO_0004529
ENSG00000084674	rs673548	2	21014672	?	Lipid metabolism phenotypes	19936222	[NR] unit decrease	0.041	EFO_0004529
ENSG00000084674	rs676210	2	21008652	?	Lipid metabolism phenotypes	19936222	[NR] unit decrease	4.219	EFO_0004529
ENSG00000084674	rs673548	2	21014672	?	Lipid metabolism phenotypes	19936222	[NR] unit decrease	6.624	EFO_0004529
ENSG00000084674	rs676210	2	21008652	?	Lipid metabolism phenotypes	19936222	[NR] unit decrease	6.384	EFO_0004529
ENSG00000084674	rs673548	2	21014672	?	Metabolite levels	22916037			EFO_0004723
ENSG00000084674	rs673548	2	21014672	A	Metabolic traits	19060910	[0.05-0.11] mmol/l decrease	0.08	EFO_0004530
ENSG00000084674	rs520354	2	21036740	G	Blood protein levels	28240269	[0.22-0.38] unit increase	0.3033	EFO_0004615
ENSG00000084674	rs693	2	21009323	A	LDL cholesterol levels	17463246	(% variance) increase	1	EFO_0004611
ENSG00000084674	rs57825321	2	21024193	?	Total cholesterol levels	29403010	[0.061-0.085] unit decrease novel	0.07307	EFO_0004574
ENSG00000084674	rs57825321	2	21024193	?	Low density lipoprotein cholesterol levels	29403010	[0.079-0.112] unit decrease novel	0.09537	EFO_0004611
ENSG00000084674	rs1367117	2	21041028	?	Low density lipoprotein cholesterol levels	29403010	[0.043-0.081] unit increase novel	0.06198	EFO_0004611
ENSG00000084674	rs10199768	2	21021128	T	Cardiovascular disease risk factors	21943158	[0.083-0.137] mmol/l increase	0.11	EFO_0004611
ENSG00000084674	rs1042034	2	21002409	C	HDL cholesterol	20686565	[0.72-1.08] mg/dL increase	0.9	EFO_0004612
ENSG00000084674	rs1367117	2	21041028	A	LDL cholesterol	20686565	[3.68-4.42] mg/dL increase	4.05	EFO_0004611
ENSG00000084674	rs1042034	2	21002409	C	Triglycerides	20686565	[5.11-6.87] mg/dL decrease	5.99	EFO_0004530
ENSG00000084674	rs673548	2	21014672	G	Metabolic syndrome	22399527	[NR] mmol/l decrease	0.11	EFO_0000195
ENSG00000084674	rs693	2	21009323	A	Triglycerides	18193044	[0.04-0.12] unit increase	0.08	EFO_0004530
ENSG00000084674	rs693	2	21009323	G	LDL cholesterol	19060911	[NR] s.d. decrease	0.1	EFO_0004611
ENSG00000084674	rs693	2	21009323	A	LDL cholesterol	19060910	[0.09-0.16] mmol/l increase	0.12	EFO_0004611
ENSG00000084674	rs1367117	2	21041028	A	LDL cholesterol levels	28334899	[0.11-0.13] unit increase (EA Beta value)	0.119	EFO_0004611
ENSG00000084674	rs1367117	2	21041028	A	Total cholesterol levels	28334899	[0.092-0.107] unit increase (EA Beta values)	0.0995	EFO_0004574
ENSG00000084674	rs679899	2	21028042	G	Blood protein levels	30072576	[NR] unit decrease	0.23186418	EFO_0007937
ENSG00000084674	rs679899	2	21028042	G	Blood protein levels	30072576	[NR] unit decrease	0.18513301	EFO_0007937
ENSG00000084674	rs679899	2	21028042	G	Blood protein levels	30072576	[NR] unit decrease	0.1736701	EFO_0007937
ENSG00000084674	rs679899	2	21028042	G	Blood protein levels	30072576	[0.2-0.29] unit decrease	0.246	EFO_0007937
ENSG00000084674	rs1042034	2	21002409	C	Low density lipoprotein cholesterol levels	29507422	unit decrease	0.054	EFO_0004611
ENSG00000084674	rs1042034	2	21002409	C	Low density lipoprotein cholesterol levels	29507422	unit decrease	0.039	EFO_0004611
ENSG00000084674	rs2678379	2	21003688	A	Low density lipoprotein cholesterol levels	29507422	unit decrease	0.052	EFO_0004611
ENSG00000084674	rs2678379	2	21003688	A	Low density lipoprotein cholesterol levels	29507422	unit decrease	0.037	EFO_0004611
ENSG00000084674	rs676210	2	21008652	G	Low density lipoprotein cholesterol levels	29507422	unit increase	0.052	EFO_0004611
ENSG00000084674	rs676210	2	21008652	G	Low density lipoprotein cholesterol levels	29507422	unit increase	0.038	EFO_0004611
ENSG00000084674	rs1041968	2	21009932	G	Low density lipoprotein cholesterol levels	29507422	unit decrease	0.102	EFO_0004611
ENSG00000084674	rs1041968	2	21009932	G	Low density lipoprotein cholesterol levels	29507422	unit decrease	0.095	EFO_0004611
ENSG00000084674	rs1041968	2	21009932	G	Low density lipoprotein cholesterol levels	29507422	unit decrease	0.101	EFO_0004611
ENSG00000084674	rs533617	2	21011100	T	Low density lipoprotein cholesterol levels	29507422	unit increase	0.151	EFO_0004611
ENSG00000084674	rs533617	2	21011100	T	Low density lipoprotein cholesterol levels	29507422	unit increase	0.151	EFO_0004611
ENSG00000084674	rs673548	2	21014672	G	Low density lipoprotein cholesterol levels	29507422	unit increase	0.053	EFO_0004611
ENSG00000084674	rs673548	2	21014672	G	Low density lipoprotein cholesterol levels	29507422	unit increase	0.037	EFO_0004611
ENSG00000084674	rs1367117	2	21041028	G	Low density lipoprotein cholesterol levels	29507422	unit decrease	0.12	EFO_0004611
ENSG00000084674	rs1367117	2	21041028	G	Low density lipoprotein cholesterol levels	29507422	unit decrease	0.126	EFO_0004611
ENSG00000084674	rs1367117	2	21041028	G	Low density lipoprotein cholesterol levels	29507422	unit decrease	0.12	EFO_0004611
ENSG00000084674	rs1042034	2	21002409	C	High density lipoprotein cholesterol levels	29507422	unit increase	0.069	EFO_0004612
ENSG00000084674	rs1042034	2	21002409	C	High density lipoprotein cholesterol levels	29507422	unit increase	0.074	EFO_0004612
ENSG00000084674	rs1042034	2	21002409	C	High density lipoprotein cholesterol levels	29507422	unit increase	0.066	EFO_0004612
ENSG00000084674	rs2678379	2	21003688	A	High density lipoprotein cholesterol levels	29507422	unit increase	0.07	EFO_0004612
ENSG00000084674	rs2678379	2	21003688	A	High density lipoprotein cholesterol levels	29507422	unit increase	0.074	EFO_0004612
ENSG00000084674	rs2678379	2	21003688	A	High density lipoprotein cholesterol levels	29507422	unit increase	0.066	EFO_0004612
ENSG00000084674	rs676210	2	21008652	G	High density lipoprotein cholesterol levels	29507422	unit decrease	0.069	EFO_0004612
ENSG00000084674	rs676210	2	21008652	G	High density lipoprotein cholesterol levels	29507422	unit decrease	0.076	EFO_0004612
ENSG00000084674	rs676210	2	21008652	G	High density lipoprotein cholesterol levels	29507422	unit decrease	0.066	EFO_0004612
ENSG00000084674	rs1041968	2	21009932	G	High density lipoprotein cholesterol levels	29507422	unit increase	0.03	EFO_0004612
ENSG00000084674	rs1041968	2	21009932	G	High density lipoprotein cholesterol levels	29507422	unit increase	0.031	EFO_0004612
ENSG00000084674	rs533617	2	21011100	T	High density lipoprotein cholesterol levels	29507422	unit decrease	0.087	EFO_0004612
ENSG00000084674	rs533617	2	21011100	T	High density lipoprotein cholesterol levels	29507422	unit decrease	0.087	EFO_0004612
ENSG00000084674	rs673548	2	21014672	G	High density lipoprotein cholesterol levels	29507422	unit decrease	0.069	EFO_0004612
ENSG00000084674	rs673548	2	21014672	G	High density lipoprotein cholesterol levels	29507422	unit decrease	0.074	EFO_0004612
ENSG00000084674	rs673548	2	21014672	G	High density lipoprotein cholesterol levels	29507422	unit decrease	0.065	EFO_0004612
ENSG00000084674	rs1367117	2	21041028	G	High density lipoprotein cholesterol levels	29507422	unit increase	0.018	EFO_0004612
ENSG00000084674	rs1042034	2	21002409	C	Total cholesterol levels	29507422	unit decrease	0.048	EFO_0004574
ENSG00000084674	rs1042034	2	21002409	C	Total cholesterol levels	29507422	unit decrease	0.035	EFO_0004574
ENSG00000084674	rs2678379	2	21003688	A	Total cholesterol levels	29507422	unit decrease	0.047	EFO_0004574
ENSG00000084674	rs2678379	2	21003688	A	Total cholesterol levels	29507422	unit decrease	0.034	EFO_0004574
ENSG00000084674	rs676210	2	21008652	G	Total cholesterol levels	29507422	unit increase	0.047	EFO_0004574
ENSG00000084674	rs676210	2	21008652	G	Total cholesterol levels	29507422	unit increase	0.034	EFO_0004574
ENSG00000084674	rs1041968	2	21009932	G	Total cholesterol levels	29507422	unit decrease	0.094	EFO_0004574
ENSG00000084674	rs1041968	2	21009932	G	Total cholesterol levels	29507422	unit decrease	0.085	EFO_0004574
ENSG00000084674	rs1041968	2	21009932	G	Total cholesterol levels	29507422	unit decrease	0.094	EFO_0004574
ENSG00000084674	rs533617	2	21011100	T	Total cholesterol levels	29507422	unit increase	0.133	EFO_0004574
ENSG00000084674	rs533617	2	21011100	T	Total cholesterol levels	29507422	unit increase	0.133	EFO_0004574
ENSG00000084674	rs673548	2	21014672	G	Total cholesterol levels	29507422	unit increase	0.048	EFO_0004574
ENSG00000084674	rs673548	2	21014672	G	Total cholesterol levels	29507422	unit increase	0.034	EFO_0004574
ENSG00000084674	rs1367117	2	21041028	G	Total cholesterol levels	29507422	unit decrease	0.109	EFO_0004574
ENSG00000084674	rs1367117	2	21041028	G	Total cholesterol levels	29507422	unit decrease	0.11	EFO_0004574
ENSG00000084674	rs1367117	2	21041028	G	Total cholesterol levels	29507422	unit decrease	0.109	EFO_0004574
ENSG00000084674	rs1042034	2	21002409	C	Triglycerides	29507422	unit decrease	0.087	EFO_0004530
ENSG00000084674	rs1042034	2	21002409	C	Triglycerides	29507422	unit decrease	0.079	EFO_0004530
ENSG00000084674	rs1042034	2	21002409	C	Triglycerides	29507422	unit decrease	0.081	EFO_0004530
ENSG00000084674	rs2678379	2	21003688	A	Triglycerides	29507422	unit decrease	0.087	EFO_0004530
ENSG00000084674	rs2678379	2	21003688	A	Triglycerides	29507422	unit decrease	0.081	EFO_0004530
ENSG00000084674	rs2678379	2	21003688	A	Triglycerides	29507422	unit decrease	0.08	EFO_0004530
ENSG00000084674	rs676210	2	21008652	G	Triglycerides	29507422	unit increase	0.087	EFO_0004530
ENSG00000084674	rs676210	2	21008652	G	Triglycerides	29507422	unit increase	0.08	EFO_0004530
ENSG00000084674	rs676210	2	21008652	G	Triglycerides	29507422	unit increase	0.081	EFO_0004530
ENSG00000084674	rs1041968	2	21009932	G	Triglycerides	29507422	unit decrease	0.051	EFO_0004530
ENSG00000084674	rs1041968	2	21009932	G	Triglycerides	29507422	unit decrease	0.052	EFO_0004530
ENSG00000084674	rs533617	2	21011100	T	Triglycerides	29507422	unit increase	0.109	EFO_0004530
ENSG00000084674	rs533617	2	21011100	T	Triglycerides	29507422	unit increase	0.108	EFO_0004530
ENSG00000084674	rs673548	2	21014672	G	Triglycerides	29507422	unit increase	0.086	EFO_0004530
ENSG00000084674	rs673548	2	21014672	G	Triglycerides	29507422	unit increase	0.078	EFO_0004530
ENSG00000084674	rs673548	2	21014672	G	Triglycerides	29507422	unit increase	0.079	EFO_0004530
ENSG00000084674	rs1367117	2	21041028	G	Triglycerides	29507422	unit decrease	0.034	EFO_0004530
ENSG00000084674	rs1367117	2	21041028	G	Triglycerides	29507422	unit decrease	0.034	EFO_0004530
ENSG00000084674	rs1042034	2	21002409	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000084674	rs1367117	2	21041028	?	Cardiovascular disease	30595370			EFO_0000319
ENSG00000084674	rs13306194	2	21029662	A	Total cholesterol levels	30718733	[2.41-5.97] unit decrease	4.1917	EFO_0004574

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000084674's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001523	retinoid metabolic process	-	TAS	Process
GO:0001701	in utero embryonic development	-	IEA	Process
GO:0002224	toll-like receptor signaling pathway	-	TAS	Process
GO:0005102	signaling receptor binding	27477018.	IPI	Function
GO:0005515	protein binding	8245722.16203724.21911577.22580899.24447298.25108285.26224785.27138255.	IPI	Function
GO:0005543	phospholipid binding	7126555.	IDA	Function
GO:0005576	extracellular region	27068509.	HDA	Component
GO:0005576	extracellular region	-	TAS	Component
GO:0005615	extracellular space	22261194.	ISS	Component
GO:0005737	cytoplasm	22580899.	IDA	Component
GO:0005769	early endosome	-	TAS	Component
GO:0005788	endoplasmic reticulum lumen	-	TAS	Component
GO:0005789	endoplasmic reticulum membrane	-	TAS	Component
GO:0005790	smooth endoplasmic reticulum	-	TAS	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	-	TAS	Component
GO:0006642	triglyceride mobilization	-	IEA	Process
GO:0006898	receptor-mediated endocytosis	-	TAS	Process
GO:0007283	spermatogenesis	-	IEA	Process
GO:0007399	nervous system development	-	IEA	Process
GO:0008201	heparin binding	16233946.	IDA	Function
GO:0008203	cholesterol metabolic process	2563166.	IMP	Process
GO:0009566	fertilization	-	IEA	Process
GO:0009615	response to virus	16548883.	IEP	Process
GO:0009743	response to carbohydrate	-	IEA	Process
GO:0009791	post-embryonic development	-	IEA	Process
GO:0010008	endosome membrane	-	TAS	Component
GO:0010269	response to selenium ion	-	IEA	Process
GO:0010628	positive regulation of gene expression	-	IEA	Process
GO:0010744	positive regulation of macrophage derived foam cell differentiation	17244792.18322245.19114110.	IDA	Process
GO:0010884	positive regulation of lipid storage	18322245.	IDA	Process
GO:0010886	positive regulation of cholesterol storage	19114110.	IDA	Process
GO:0017127	cholesterol transporter activity	15797858.	IMP	Function
GO:0019433	triglyceride catabolic process	-	IEA	Process
GO:0030301	cholesterol transport	2563166.	IMP	Process
GO:0030317	flagellated sperm motility	-	IEA	Process
GO:0030669	clathrin-coated endocytic vesicle membrane	-	TAS	Component
GO:0031904	endosome lumen	-	TAS	Component
GO:0032355	response to estradiol	-	IEA	Process
GO:0032496	response to lipopolysaccharide	-	IEA	Process
GO:0033344	cholesterol efflux	-	IEA	Process
GO:0034359	mature chylomicron	4363408.	IDA	Component
GO:0034360	chylomicron remnant	6099394.	TAS	Component
GO:0034361	very-low-density lipoprotein particle	4363408.15308631.	IDA	Component
GO:0034361	very-low-density lipoprotein particle	27477018.	TAS	Component
GO:0034362	low-density lipoprotein particle	4363408.	IDA	Component
GO:0034362	low-density lipoprotein particle	27477018.	TAS	Component
GO:0034363	intermediate-density lipoprotein particle	1917954.	IDA	Component
GO:0034364	high-density lipoprotein particle	-	IEA	Component
GO:0034371	chylomicron remodeling	-	TAS	Process
GO:0034374	low-density lipoprotein particle remodeling	15797858.	IMP	Process
GO:0034374	low-density lipoprotein particle remodeling	-	TAS	Process
GO:0034378	chylomicron assembly	-	TAS	Process
GO:0034379	very-low-density lipoprotein particle assembly	15308631.	IC	Process
GO:0034379	very-low-density lipoprotein particle assembly	-	TAS	Process
GO:0034382	chylomicron remnant clearance	-	TAS	Process
GO:0034383	low-density lipoprotein particle clearance	2563166.15797858.	IMP	Process
GO:0034383	low-density lipoprotein particle clearance	-	TAS	Process
GO:0034447	very-low-density lipoprotein particle clearance	-	TAS	Process
GO:0035473	lipase binding	9685400.	IPI	Function
GO:0042158	lipoprotein biosynthetic process	-	IEA	Process
GO:0042159	lipoprotein catabolic process	-	IEA	Process
GO:0042627	chylomicron	4363408.8245722.	IDA	Component
GO:0042632	cholesterol homeostasis	2563166.	IMP	Process
GO:0042953	lipoprotein transport	-	IEA	Process
GO:0043025	neuronal cell body	22897442.	IDA	Component
GO:0043202	lysosomal lumen	-	TAS	Component
GO:0043231	intracellular membrane-bounded organelle	-	IDA	Component
GO:0043687	post-translational protein modification	-	TAS	Process
GO:0044267	cellular protein metabolic process	-	TAS	Process
GO:0045540	regulation of cholesterol biosynthetic process	-	IEA	Process
GO:0048844	artery morphogenesis	-	IEA	Process
GO:0050750	low-density lipoprotein particle receptor binding	2563166.15797858.	IMP	Function
GO:0050900	leukocyte migration	-	TAS	Process
GO:0061024	membrane organization	-	TAS	Process
GO:0070062	extracellular exosome	23533145.	HDA	Component
GO:0070971	endoplasmic reticulum exit site	27138255.	IDA	Component
GO:0071356	cellular response to tumor necrosis factor	-	IEA	Process
GO:0071379	cellular response to prostaglandin stimulus	-	IEA	Process
GO:0071682	endocytic vesicle lumen	-	TAS	Component

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
23631828	Identification of potential bladder cancer markers in urine by abundant-protein depletion coupled with quantitative proteomics.	J Proteomics	2013 Jun 24	Chen CL	doi: 10.1016/j.jprot.2013.04.024
18296645	Polymorphisms of genes in the lipid metabolism pathway and risk of biliary tract cancers and stones: a population-based case-control study in Shanghai, China.	Cancer Epidemiol Biomarkers Prev	2008 Mar	Andreotti G	doi: 10.1158/1055-9965.EPI-07-2704
23637837	Roles of ApoB-100 gene polymorphisms and the risks of gallstones and gallbladder cancer: a meta-analysis.	PLoS One	2013 Apr 18	Gong Y	doi: 10.1371/journal.pone.0061456
14618390	Apolipoprotein B-100 XbaI gene polymorphism in gallbladder cancer.	Hum Genet	2004 Feb	Singh MK	-
23444115	Associations of polymorphisms of rs693 and rs1042031 in apolipoprotein B gene with risk of breast cancer in Chinese.	Jpn J Clin Oncol	2013 Apr	Liu X	doi: 10.1093/jjco/hyt018
17696941	Haplotype analysis of signal peptide (insertion/deletion) and XbaI polymorphisms of the APOB gene in gallbladder cancer.	Liver Int	2007 Sep	Pandey SN	-

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chr2	21008376	Missense_Mutation	novel	S2831Y	0.44
ACC	chr2	21010374	Missense_Mutation	novel	I2165N	0.41
ACC	chr2	21001987	Frame_Shift_Del	novel	*S4479Afs9**	0.37
ACC	chr2	21005546	Silent	novel	L3774L	0.23
ACC	chr2	21010652	Silent	novel	P2072P	0.09
BLCA	chr2	21007554	Missense_Mutation	novel	G3105A	0.23
BLCA	chr2	21006142	Missense_Mutation	novel	L3576I	0.86
BLCA	chr2	21012356	Silent	novel	S1504S	0.27
BLCA	chr2	21035705	Missense_Mutation	NA	R233C	0.42
BLCA	chr2	21010964	Silent	NA	V1968V	0.36
BLCA	chr2	21005149	Missense_Mutation	NA	D3907N	0.25
BLCA	chr2	21009895	Missense_Mutation	novel	I2325F	0.16
BLCA	chr2	21002801	Silent	NA	K4207K	0.15
BLCA	chr2	21015532	Nonsense_Mutation	novel	E1116*	0.29
BLCA	chr2	21005822	Missense_Mutation	novel	K3682N	0.14
BLCA	chr2	21002308	Missense_Mutation	novel	Q4372E	0.08
BLCA	chr2	21012310	Silent	novel	L1520L	0.23
BLCA	chr2	21001935	Missense_Mutation	NA	R4496T	0.22
BLCA	chr2	21005206	Missense_Mutation	novel	E3888Q	0.07
BLCA	chr2	21006944	Silent	rs370661042	H3308H	0.38
BLCA	chr2	21026940	Missense_Mutation	novel	E698Q	0.17
BLCA	chr2	21007329	Missense_Mutation	novel	N3180S	0.44
BLCA	chr2	21006850	Missense_Mutation	novel	D3340H	0.16
BLCA	chr2	21016645	Silent	rs547789079	A1042A	0.21
BLCA	chr2	21007891	Missense_Mutation	novel	D2993H	0.35
BLCA	chr2	21011939	Silent	novel	A1643A	0.43
BLCA	chr2	21016518	Missense_Mutation	NA	E1085K	0.3
BLCA	chr2	21027830	Missense_Mutation	NA	E689K	0.26
BLCA	chr2	21005345	Silent	NA	N3841N	0.3
BLCA	chr2	21006394	Missense_Mutation	NA	I3492F	0.18
BLCA	chr2	21003180	Missense_Mutation	novel	L4081H	0.1
BLCA	chr2	21008476	Missense_Mutation	novel	E2798Q	0.06
BLCA	chr2	21023675	Silent	novel	R818R	0.26
BLCA	chr2	21025092	Silent	novel	E759E	0.28
BLCA	chr2	21026793	Missense_Mutation	rs756379920	E747Q	0.25
BLCA	chr2	21011978	Missense_Mutation	novel	I1630M	0.45
BLCA	chr2	21019746	Silent	novel	Y992Y	0.23
BLCA	chr2	21006913	Missense_Mutation	novel	D3319N	0.1
BLCA	chr2	21010261	Missense_Mutation	NA	D2203H	0.28
BLCA	chr2	21010353	Missense_Mutation	novel	S2172Y	0.26
BLCA	chr2	21035660	Missense_Mutation	novel	T248S	0.29
BLCA	chr2	21015246	Missense_Mutation	novel	E1175Q	0.09
BLCA	chr2	21010633	Missense_Mutation	NA	E2079K	0.21
BLCA	chr2	21010424	Missense_Mutation	novel	K2148N	0.06
BLCA	chr2	21019754	Missense_Mutation	rs139434026	A990T	0.39
BLCA	chr2	21016474	Missense_Mutation	novel	K1099N	0.44
BLCA	chr2	21006444	Missense_Mutation	novel	G3475A	0.34
BLCA	chr2	21037967	Frame_Shift_Ins	rs780123326	*L177Vfs30**	0.45
BLCA	chr2	21006384	Missense_Mutation	novel	S3495C	0.14
BLCA	chr2	21025086	Silent	novel	L761L	0.12
BLCA	chr2	21015166	Silent	novel	P1201P	0.47
BRCA	chr2	21001963	Frame_Shift_Del	NA	I4487*	0.48
BRCA	chr2	21013388	Missense_Mutation	NA	L1330M	0.19
BRCA	chr2	21013378	Missense_Mutation	NA	R1333Q	0.35
BRCA	chr2	21010384	Missense_Mutation	NA	D2162Y	0.34
BRCA	chr2	21001975	Missense_Mutation	novel	A4483T	0.17
BRCA	chr2	21006870	Missense_Mutation	NA	A3333V	0.44
BRCA	chr2	21023527	Missense_Mutation	NA	N868D	0.16
BRCA	chr2	21019871	Missense_Mutation	NA	E951Q	0.21
BRCA	chr2	21038102	Silent	NA	L131L	0.23
BRCA	chr2	21009547	Missense_Mutation	rs765524771	D2441N	0.23
BRCA	chr2	21008869	Missense_Mutation	NA	E2667Q	0.21
BRCA	chr2	21003275	Silent	NA	D4049D	0.34
BRCA	chr2	21012220	Missense_Mutation	NA	L1550M	0.47
BRCA	chr2	21011253	Missense_Mutation	NA	I1872N	0.19
BRCA	chr2	21009268	Nonsense_Mutation	rs145143533	R2534*	0.43
BRCA	chr2	21016645	Silent	rs547789079	A1042A	0.08
BRCA	chr2	21010134	Missense_Mutation	novel	T2245S	0.12
BRCA	chr2	21013209	Silent	NA	Y1389Y	0.28
BRCA	chr2	21008476	Missense_Mutation	novel	E2798Q	0.43
BRCA	chr2	21032407	Silent	novel	A433A	0.38
BRCA	chr2	21002399	Silent	novel	I4341I	0.18
BRCA	chr2	21008733	Missense_Mutation	rs368283618	R2712H	0.03
BRCA	chr2	21019001	Nonsense_Mutation	NA	Q1038*	0.48
BRCA	chr2	21016529	Frame_Shift_Del	novel	I1076*	0.07
BRCA	chr2	21022869	Missense_Mutation	NA	I926M	0.27
BRCA	chr2	21028459	Missense_Mutation	NA	M566T	0.33
BRCA	chr2	21028460	Missense_Mutation	NA	M566L	0.32
BRCA	chr2	21015439	Missense_Mutation	novel	L1147I	0.18
BRCA	chr2	21008984	Silent	NA	S2628S	0.44
BRCA	chr2	21005869	In_Frame_Del	NA	E3666del	0.17
BRCA	chr2	21007645	Missense_Mutation	NA	A3075T	0.18
BRCA	chr2	21016563	Missense_Mutation	NA	D1070H	0.2
BRCA	chr2	21005978	Missense_Mutation	rs768105768	K3630N	0.64
BRCA	chr2	21008678	Missense_Mutation	novel	D2730E	0.1
BRCA	chr2	21012034	Missense_Mutation	NA	F1612L	0.24
BRCA	chr2	21008329	Missense_Mutation	NA	G2847R	0.4
BRCA	chr2	21002896	Missense_Mutation	NA	V4176I	0.19
BRCA	chr2	21025098	Silent	NA	S757S	0.23
BRCA	chr2	21009709	Frame_Shift_Del	novel	*I2386Rfs4**	0.26
BRCA	chr2	21009398	Silent	NA	T2490T	0.35
BRCA	chr2	21010771	Missense_Mutation	rs747111881	P2033S	0.14
BRCA	chr2	21006450	Missense_Mutation	NA	A3473V	0.3
BRCA	chr2	21009386	Missense_Mutation	NA	N2494K	0.21
BRCA	chr2	21007129	Missense_Mutation	NA	Q3247E	0.29
BRCA	chr2	21013376	Missense_Mutation	NA	E1334Q	0.31
BRCA	chr2	21005181	Missense_Mutation	rs759708973	A3896V	0.18
BRCA	chr2	21006772	Missense_Mutation	NA	L3366I	0.35
BRCA	chr2	21007948	Missense_Mutation	NA	L2974V	0.15
BRCA	chr2	21015202	Missense_Mutation	NA	M1189I	0.15
BRCA	chr2	21011006	Silent	novel	L1954L	0.04
BRCA	chr2	21005474	Frame_Shift_Ins	novel	*K3799Lfs12**	0.13
BRCA	chr2	21009586	In_Frame_Ins	novel	L2427_K2428insFF	0.17
BRCA	chr2	21009588	Frame_Shift_Ins	novel	*L2427Wfs8**	0.15
BRCA	chr2	21011033	Frame_Shift_Ins	novel	*D1945Efs23**	0.08
BRCA	chr2	21011205	In_Frame_Del	novel	D1888del	0.11
BRCA	chr2	21025103	Missense_Mutation	NA	L756F	0.39
BRCA	chr2	21026944	Silent	novel	G696G	0.21
BRCA	chr2	21005266	Nonsense_Mutation	novel	K3868*	0.1
BRCA	chr2	21009526	Missense_Mutation	NA	Q2448E	0.17
BRCA	chr2	21010963	Missense_Mutation	novel	S1969G	0.09
BRCA	chr2	21001876	Missense_Mutation	NA	E4516K	0.12
BRCA	chr2	21011865	Missense_Mutation	novel	E1668G	0.08
BRCA	chr2	21010523	Silent	NA	L2115L	0.22
BRCA	chr2	21008143	Missense_Mutation	rs200824333	E2909K	0.09
BRCA	chr2	21006635	Missense_Mutation	rs771372599	N3411K	0.44
BRCA	chr2	21008391	Missense_Mutation	NA	E2826G	0.33
BRCA	chr2	21010227	Missense_Mutation	novel	E2214V	0.08
CESC	chr2	21013272	Missense_Mutation	novel	N1368K	0.06
CESC	chr2	21005760	Missense_Mutation	novel	R3703H	0.31
CESC	chr2	21008834	Silent	NA	Q2678Q	0.16
CESC	chr2	21005464	Missense_Mutation	NA	Q3802E	0.24
CESC	chr2	21018995	Missense_Mutation	NA	E1040K	0.31
CESC	chr2	21023650	Missense_Mutation	NA	L827V	0.2
CESC	chr2	21008130	Missense_Mutation	NA	L2913R	0.15
CESC	chr2	21009867	Missense_Mutation	NA	I2334S	0.15
CESC	chr2	21010207	Missense_Mutation	NA	N2221H	0.41
CESC	chr2	21007427	Silent	novel	L3147L	0.21
CESC	chr2	21006961	Missense_Mutation	NA	E3303K	0.4
CESC	chr2	21024990	Silent	rs768889458	Q793Q	0.32
CESC	chr2	21023527	Missense_Mutation	NA	N868D	0.22
CESC	chr2	21015192	Frame_Shift_Ins	novel	*F1193Nfs30**	0.1
CESC	chr2	21015193	Missense_Mutation	novel	N1192K	0.1
CESC	chr2	21002491	Missense_Mutation	novel	E4311Q	0.08
CESC	chr2	21038024	Silent	NA	K157K	0.46
CESC	chr2	21010747	Missense_Mutation	NA	E2041Q	0.31
CESC	chr2	21007993	Silent	novel	L2959L	0.42
CESC	chr2	21008200	Missense_Mutation	novel	F2890V	0.4
CESC	chr2	21010031	Silent	rs747345046	Q2279Q	0.2
CESC	chr2	21001631	3'UTR	novel		0.41
CESC	chr2	21007148	Silent	rs111899014	D3240D	0.1
CESC	chr2	21008780	Silent	rs760919952	L2696L	0.09
CESC	chr2	21005923	Missense_Mutation	rs754128155	E3649K	0.13
CESC	chr2	21029690	Missense_Mutation	NA	M522I	0.16
CESC	chr2	21006092	Silent	novel	S3592S	0.08
CESC	chr2	21001549	3'UTR	novel		0.28
CESC	chr2	21007233	Missense_Mutation	NA	R3212T	0.19
CESC	chr2	21011770	Missense_Mutation	NA	D1700N	0.24
CESC	chr2	21026802	Missense_Mutation	NA	D744N	0.56
CESC	chr2	21003038	Silent	NA	V4128V	0.43
CESC	chr2	21033394	Missense_Mutation	novel	Q343H	0.43
CHOL	chr2	21002661	Frame_Shift_Del	novel	*P4254Lfs4**	0.23
CHOL	chr2	21012298	Missense_Mutation	novel	S1524P	0.45
CHOL	chr2	21023650	Missense_Mutation	novel	L827I	0.12
COAD	chr2	21002993	Silent	novel	E4143E	0.28
COAD	chr2	21025124	Missense_Mutation	novel	D749Y	0.25
COAD	chr2	21007397	Silent	NA	G3157G	0.4
COAD	chr2	21002624	Silent	NA	I4266I	0.29
COAD	chr2	21005764	Missense_Mutation	NA	L3702I	0.43
COAD	chr2	21007391	Missense_Mutation	NA	K3159N	0.4
COAD	chr2	21007522	Nonsense_Mutation	NA	G3116*	0.32
COAD	chr2	21009898	Missense_Mutation	NA	L2324I	0.33
COAD	chr2	21012387	Missense_Mutation	NA	S1494L	0.29
COAD	chr2	21028030	Missense_Mutation	NA	S622Y	0.36
COAD	chr2	21042470	Missense_Mutation	NA	A43V	0.4
COAD	chr2	21011188	Missense_Mutation	novel	N1894D	0.08
COAD	chr2	21007104	Missense_Mutation	novel	V3255D	0.25
COAD	chr2	21015258	Missense_Mutation	NA	E1171K	0.36
COAD	chr2	21008405	Silent	NA	P2821P	0.49
COAD	chr2	21001528	3'UTR	novel		0.15
COAD	chr2	21032374	Silent	NA	A444A	0.26
COAD	chr2	21006808	Missense_Mutation	novel	A3354S	0.08
COAD	chr2	21005181	Missense_Mutation	rs759708973	A3896V	0.23
COAD	chr2	21007562	Missense_Mutation	NA	F3102L	0.29
COAD	chr2	21012458	Missense_Mutation	novel	H1470Q	0.27
COAD	chr2	21012617	Silent	rs72653082	T1417T	0.3
COAD	chr2	21006359	Silent	rs769351301	S3503S	0.31
COAD	chr2	21022925	Missense_Mutation	rs761179789	E908K	0.17
COAD	chr2	21012618	Missense_Mutation	rs200321839	T1417M	0.23
COAD	chr2	21010151	Missense_Mutation	novel	N2239K	0.2
COAD	chr2	21005307	Missense_Mutation	novel	T3854I	0.08
COAD	chr2	21015197	Missense_Mutation	novel	S1191F	0.05
COAD	chr2	21004558	Splice_Region	rs564171124		0.27
COAD	chr2	21038060	Silent	rs576323709	P145P	0.36
COAD	chr2	21008955	Missense_Mutation	novel	N2638T	0.47
COAD	chr2	21012206	Silent	NA	I1554I	0.18
COAD	chr2	21009174	Missense_Mutation	novel	A2565E	0.04
COAD	chr2	21006678	Missense_Mutation	novel	T3397I	0.21
COAD	chr2	21002749	Missense_Mutation	NA	G4225R	0.32
COAD	chr2	21007852	Missense_Mutation	NA	G3006C	0.33
COAD	chr2	21008074	Frame_Shift_Del	novel	*A2932Pfs19**	0.36
COAD	chr2	21019062	Silent	rs558838327	S1017S	0.45
COAD	chr2	21001800	Frame_Shift_Del	NA	*K4541Sfs8**	0.17
COAD	chr2	21010772	Silent	rs768573736	E2032E	0.17
COAD	chr2	21011106	Frame_Shift_Del	novel	*G1921Efs13**	0.19
COAD	chr2	21011468	Silent	NA	D1800D	0.15
COAD	chr2	21029702	Silent	novel	K518K	0.21
COAD	chr2	21007352	Silent	NA	S3172S	0.23
COAD	chr2	21029993	Missense_Mutation	NA	G459W	0.25
COAD	chr2	21007808	Silent	novel	R3020R	0.29
COAD	chr2	21010326	Missense_Mutation	novel	F2181C	0.24
COAD	chr2	21012403	Missense_Mutation	novel	Q1489K	0.27
COAD	chr2	21004331	Missense_Mutation	rs140424976	V4009M	0.17
COAD	chr2	21008623	Missense_Mutation	novel	T2749A	0.11
COAD	chr2	21030014	Missense_Mutation	novel	Y452N	0.11
COAD	chr2	21005924	Silent	rs370314131	V3648V	0.16
COAD	chr2	21013460	Missense_Mutation	novel	S1306P	0.23
COAD	chr2	21010731	Missense_Mutation	novel	V2046A	0.16
COAD	chr2	21002681	Missense_Mutation	NA	Q4247H	0.4
COAD	chr2	21012518	Missense_Mutation	NA	K1450N	0.36
COAD	chr2	21016642	Missense_Mutation	NA	K1043N	0.08
COAD	chr2	21010358	Missense_Mutation	novel	K2170N	0.44
COAD	chr2	21006365	Missense_Mutation	NA	K3501N	0.11
COAD	chr2	21010190	Silent	NA	I2226I	0.08
COAD	chr2	21012517	Missense_Mutation	NA	G1451C	0.07
COAD	chr2	21015526	Missense_Mutation	novel	R1118G	0.11
COAD	chr2	21002268	Missense_Mutation	rs533755016	R4385H	0.33
COAD	chr2	21003033	Missense_Mutation	novel	F4130C	0.21
COAD	chr2	21007807	Missense_Mutation	novel	H3021N	0.17
COAD	chr2	21007462	Missense_Mutation	rs72653102	R3136C	0.34
COAD	chr2	21011805	Missense_Mutation	novel	G1688V	0.32
COAD	chr2	21002546	Silent	NA	T4292T	0.33
COAD	chr2	21015204	Frame_Shift_Del	NA	M1189*	0.34
COAD	chr2	21005924	Silent	rs370314131	V3648V	0.39
COAD	chr2	21001895	Nonsense_Mutation	NA	Y4509*	0.14
COAD	chr2	21002453	Silent	NA	T4323T	0.31
COAD	chr2	21002457	Missense_Mutation	rs533551460	F4322C	0.13
COAD	chr2	21002724	Missense_Mutation	rs377125320	S4233L	0.1
COAD	chr2	21002931	Missense_Mutation	novel	F4164S	0.1
COAD	chr2	21005327	Silent	NA	I3847I	0.11
COAD	chr2	21006360	Missense_Mutation	rs375284245	S3503L	0.11
COAD	chr2	21007385	Missense_Mutation	novel	F3161L	0.24
COAD	chr2	21009808	Missense_Mutation	NA	I2354L	0.1
COAD	chr2	21010717	Nonsense_Mutation	novel	E2051*	0.07
COAD	chr2	21012176	Missense_Mutation	NA	E1564D	0.08
COAD	chr2	21027844	Nonsense_Mutation	NA	S684*	0.15
COAD	chr2	21033432	Nonsense_Mutation	NA	E331*	0.16
COAD	chr2	21024931	Splice_Site	NA	X812_splice	0.36
COAD	chr2	21011744	Silent	novel	L1708L	0.26
COAD	chr2	21004566	Silent	novel	G3966G	0.31
COAD	chr2	21007510	Nonsense_Mutation	novel	E3120*	0.25
COAD	chr2	21019785	Silent	rs145649470	G979G	0.32
COAD	chr2	21001800	Frame_Shift_Del	NA	*K4541Sfs8**	0.34
COAD	chr2	21010424	Frame_Shift_Ins	NA	*Y2149Vfs2**	0.37
COAD	chr2	21038010	Missense_Mutation	novel	S162Y	0.06
COAD	chr2	21009833	Silent	rs368113811	I2345I	0.23
COAD	chr2	21027831	Missense_Mutation	rs774188993	I688M	0.13
COAD	chr2	21003017	Silent	novel	S4135S	0.3
COAD	chr2	21016458	Missense_Mutation	rs375294575	A1105T	0.46
COAD	chr2	21009111	Missense_Mutation	novel	T2586I	0.04
COAD	chr2	21010424	Frame_Shift_Ins	NA	*Y2149Vfs2**	0.21
COAD	chr2	21002723	Silent	rs56675344	S4233S	0.29
COAD	chr2	21005261	Silent	NA	F3869F	0.09
COAD	chr2	21006600	Missense_Mutation	rs761983757	V3423A	0.16
COAD	chr2	21007142	Silent	NA	L3242L	0.19
COAD	chr2	21008571	Missense_Mutation	NA	S2766Y	0.15
COAD	chr2	21011008	Missense_Mutation	novel	L1954I	0.07
COAD	chr2	21011939	Silent	rs200623857	A1643A	0.15
COAD	chr2	21032422	Missense_Mutation	NA	E428D	0.27
COAD	chr2	21010227	Missense_Mutation	novel	E2214G	0.23
COAD	chr2	21028483	Missense_Mutation	rs766083346	R558Q	0.4
COAD	chr2	21005271	Frame_Shift_Ins	novel	*S3866Yfs21**	0.06
COAD	chr2	21022971	Silent	rs759072451	P892P	0.43
DLBC	chr2	21016570	Silent	rs200281277	P1067P	0.09
ESCA	chr2	21010349	Missense_Mutation	NA	Q2173H	0.29
ESCA	chr2	21009798	Nonsense_Mutation	novel	L2357*	0.23
ESCA	chr2	21037257	Splice_Site	NA	X180_splice	0.51
ESCA	chr2	21029783	Splice_Region	novel	V491V	0.22
ESCA	chr2	21003242	Missense_Mutation	novel	E4060D	0.55
ESCA	chr2	21009310	Nonsense_Mutation	rs746483297	R2520*	0.3
ESCA	chr2	21007929	Missense_Mutation	novel	S2980C	0.12
ESCA	chr2	21008495	Silent	novel	A2791A	0.3
ESCA	chr2	21007235	Frame_Shift_Ins	NA	*N3211Kfs14**	0.27
ESCA	chr2	21004411	Missense_Mutation	rs747463777	A3982V	0.43
ESCA	chr2	21011749	Missense_Mutation	novel	E1707K	0.4
ESCA	chr2	21006805	Missense_Mutation	rs776374541	E3355K	0.07
ESCA	chr2	21006807	Missense_Mutation	rs61742331	A3354G	0.13
ESCA	chr2	21009991	Missense_Mutation	novel	D2293N	0.15
ESCA	chr2	21006645	Missense_Mutation	novel	G3408V	0.44
ESCA	chr2	21007058	Silent	rs138010392	F3270F	0.23
ESCA	chr2	21012569	Silent	rs376103623	S1433S	0.4
ESCA	chr2	21009031	Missense_Mutation	NA	Q2613K	0.09
ESCA	chr2	21034852	Missense_Mutation	novel	D290N	0.23
ESCA	chr2	21008838	Missense_Mutation	novel	D2677A	0.36
ESCA	chr2	21006100	Missense_Mutation	novel	E3590Q	0.28
ESCA	chr2	21015464	Silent	rs140456702	L1138L	0.18
ESCA	chr2	21011801	Silent	novel	R1689R	0.19
GBM	chr2	21005840	Silent	NA	I3676I	0.33
GBM	chr2	21004640	Missense_Mutation	NA	A3942T	0.29
GBM	chr2	21002529	Missense_Mutation	novel	N4298I	0.05
GBM	chr2	21008621	Silent	novel	T2749T	0.06
GBM	chr2	21011009	Missense_Mutation	novel	H1953Q	0.13
GBM	chr2	21007461	Missense_Mutation	rs199590149	R3136H	0.19
GBM	chr2	21002891	Silent	NA	R4177R	0.37
GBM	chr2	21008616	Missense_Mutation	novel	E2751A	0.05
GBM	chr2	21010456	Missense_Mutation	novel	A2138S	0.12
GBM	chr2	21032353	Splice_Site	novel	X451_splice	0.22
GBM	chr2	21027980	Missense_Mutation	novel	L639I	0.33
GBM	chr2	21004650	Missense_Mutation	novel	D3938E	0.1
GBM	chr2	21007229	Missense_Mutation	novel	N3213K	0.35
GBM	chr2	21028034	Nonsense_Mutation	novel	E621*	0.25
GBM	chr2	21033408	Nonsense_Mutation	NA	E339*	0.27
GBM	chr2	21006468	Nonsense_Mutation	novel	S3467*	0.07
GBM	chr2	21006214	Missense_Mutation	novel	G3552R	0.19
GBM	chr2	21022921	Missense_Mutation	rs776209966	S909L	0.14
GBM	chr2	21010834	Nonsense_Mutation	rs147863759	R2012*	0.38
GBM	chr2	21008849	In_Frame_Ins	novel	I2673_R2674insCPTIFQDILKSH	0.12
GBM	chr2	21006971	Silent	novel	L3299L	0.21
GBM	chr2	21007761	Missense_Mutation	novel	S3036F	0.29
GBM	chr2	21010437	Missense_Mutation	novel	A2144V	0.3
GBM	chr2	21013402	Missense_Mutation	NA	S1325Y	0.05
GBM	chr2	21015200	Missense_Mutation	novel	T1190N	0.24
GBM	chr2	21043516	Missense_Mutation	novel	P40S	0.28
GBM	chr2	21008311	Nonsense_Mutation	novel	K2853*	0.32
GBM	chr2	21007826	Missense_Mutation	novel	K3014N	0.07
GBM	chr2	21026898	Missense_Mutation	NA	P712S	0.36
GBM	chr2	21033423	Missense_Mutation	novel	K334E	0.08
GBM	chr2	21006249	Missense_Mutation	novel	D3540G	0.1
GBM	chr2	21006615	Missense_Mutation	rs765298217	T3418K	0.15
GBM	chr2	21009466	Silent	novel	L2468L	0.34
GBM	chr2	21006614	Silent	rs781639766	T3418T	0.3
GBM	chr2	21015198	Missense_Mutation	novel	S1191P	0.17
GBM	chr2	21009430	Missense_Mutation	novel	Y2480N	0.07
GBM	chr2	21002182	Missense_Mutation	novel	L4414V	0.11
GBM	chr2	21016459	Silent	rs780454824	V1104V	0.36
GBM	chr2	21002723	Silent	rs56675344	S4233S	0.23
GBM	chr2	21012346	Missense_Mutation	NA	D1508N	0.05
GBM	chr2	21010585	Missense_Mutation	rs200874264	V2095I	0.39
GBM	chr2	21005745	Missense_Mutation	novel	F3708Y	0.1
GBM	chr2	21011257	Missense_Mutation	novel	D1871Y	0.03
GBM	chr2	21004305	Silent	rs12713501	D4017D	0.26
GBM	chr2	21009051	Missense_Mutation	NA	A2606V	0.33
GBM	chr2	21034869	Missense_Mutation	novel	Q284L	0.08
HNSC	chr2	21009052	Missense_Mutation	novel	A2606T	0.28
HNSC	chr2	21019732	Missense_Mutation	novel	G997A	0.44
HNSC	chr2	21009444	Missense_Mutation	novel	A2475D	0.21
HNSC	chr2	21015537	Missense_Mutation	rs754723900	T1114I	0.19
HNSC	chr2	21019744	Missense_Mutation	rs762080553	Y993C	0.23
HNSC	chr2	21008230	Nonsense_Mutation	rs760198312	Q2880*	0.09
HNSC	chr2	21011281	Missense_Mutation	novel	E1863Q	0.25
HNSC	chr2	21010186	Missense_Mutation	novel	D2228N	0.06
HNSC	chr2	21011516	Silent	novel	V1784V	0.14
HNSC	chr2	21023037	Silent	novel	Q870Q	0.17
HNSC	chr2	21005946	Missense_Mutation	novel	S3641Y	0.35
HNSC	chr2	21008930	Silent	novel	S2646S	0.15
HNSC	chr2	21011264	Silent	novel	L1868L	0.25
HNSC	chr2	21032558	Missense_Mutation	NA	V383A	0.34
HNSC	chr2	21008665	Missense_Mutation	novel	D2735H	0.16
HNSC	chr2	21008532	Missense_Mutation	novel	N2779I	0.39
HNSC	chr2	21012072	Missense_Mutation	rs746414462	R1599H	0.19
HNSC	chr2	21002923	Missense_Mutation	novel	L4167F	0.09
HNSC	chr2	21007287	Missense_Mutation	novel	C3194F	0.32
HNSC	chr2	21008947	Frame_Shift_Del	novel	*I2641Sfs26**	0.14
HNSC	chr2	21006288	Missense_Mutation	novel	R3527P	0.36
HNSC	chr2	21032374	Silent	NA	A444A	0.07
HNSC	chr2	21008512	Missense_Mutation	rs373774326	E2786K	0.16
HNSC	chr2	21002013	Missense_Mutation	novel	S4470F	0.14
HNSC	chr2	21001817	Silent	novel	I4535I	0.37
HNSC	chr2	21010650	Missense_Mutation	novel	F2073S	0.36
HNSC	chr2	21008456	Silent	novel	L2804L	0.21
HNSC	chr2	21023587	Missense_Mutation	novel	I848L	0.33
HNSC	chr2	21016485	Missense_Mutation	novel	I1096V	0.12
HNSC	chr2	21006109	Missense_Mutation	novel	A3587T	0.15
HNSC	chr2	21013532	Missense_Mutation	rs781366272	D1282N	0.39
HNSC	chr2	21008855	Missense_Mutation	novel	K2671N	0.12
HNSC	chr2	21009505	Nonsense_Mutation	novel	Q2455*	0.17
HNSC	chr2	21010586	Silent	rs753672830	N2094N	0.19
HNSC	chr2	21012343	Missense_Mutation	NA	P1509S	0.05
HNSC	chr2	21024993	Silent	novel	L792L	0.2
HNSC	chr2	21007497	Missense_Mutation	novel	D3124G	0.17
HNSC	chr2	21009758	Silent	rs755657242	L2370L	0.18
HNSC	chr2	21003325	Missense_Mutation	novel	D4033N	0.27
HNSC	chr2	21010723	Missense_Mutation	novel	P2049S	0.07
HNSC	chr2	21008328	Missense_Mutation	novel	G2847V	0.18
HNSC	chr2	21007170	Missense_Mutation	novel	Y3233C	0.4
HNSC	chr2	21012613	Missense_Mutation	novel	T1419S	0.14
HNSC	chr2	21003241	Missense_Mutation	novel	E4061K	0.26
HNSC	chr2	21008734	Missense_Mutation	novel	R2712S	0.3
HNSC	chr2	21008735	Missense_Mutation	novel	F2711L	0.3
HNSC	chr2	21029910	Silent	novel	Y486Y	0.36
HNSC	chr2	21013418	Missense_Mutation	novel	A1320P	0.07
HNSC	chr2	21011860	Nonsense_Mutation	novel	E1670*	0.22
HNSC	chr2	21001763	Missense_Mutation	novel	K4553N	0.14
HNSC	chr2	21005843	Silent	novel	I3675I	0.38
HNSC	chr2	21022845	Missense_Mutation	novel	K934N	0.24
HNSC	chr2	21010665	Missense_Mutation	NA	S2068Y	0.24
HNSC	chr2	21008811	Missense_Mutation	novel	W2686L	0.07
HNSC	chr2	21012097	Missense_Mutation	novel	F1591I	0.12
HNSC	chr2	21019783	Missense_Mutation	novel	A980V	0.47
HNSC	chr2	21008005	Missense_Mutation	novel	T2955A	0.31
HNSC	chr2	21012354	Missense_Mutation	novel	C1505F	0.17
HNSC	chr2	21042373	Silent	NA	R75R	0.17
HNSC	chr2	21010615	Nonsense_Mutation	rs121918386	R2085*	0.09
KIRC	chr2	21006364	Missense_Mutation	rs751352552	G3502C	0.44
KIRC	chr2	21010484	Silent	NA	S2128S	0.27
KIRC	chr2	21002902	Missense_Mutation	NA	G4174S	0.26
KIRC	chr2	21006144	Frame_Shift_Del	novel	*G3575Afs48**	0.18
KIRC	chr2	21025009	Missense_Mutation	NA	A787V	0.19
KIRC	chr2	21002804	Silent	NA	G4206G	0.53
KIRP	chr2	21028445	Nonsense_Mutation	NA	Q571*	0.39
KIRP	chr2	21037976	Silent	NA	A173A	0.57
KIRP	chr2	21015411	Missense_Mutation	NA	A1156V	0.17
KIRP	chr2	21015427	Missense_Mutation	NA	D1151N	0.35
KIRP	chr2	21004591	Missense_Mutation	rs777208936	Y3958C	0.25
KIRP	chr2	21002048	Frame_Shift_Ins	novel	*D4459Rfs20**	0.32
LAML	chr2	21012526	Missense_Mutation	NA	V1448I	0.36
LAML	chr2	21012574	Missense_Mutation	novel	D1432N	0.47
LGG	chr2	21010353	Missense_Mutation	novel	S2172F	0.11
LGG	chr2	21005596	Missense_Mutation	rs781117588	V3758F	0.17
LGG	chr2	21014569	Missense_Mutation	novel	A1241P	0.07
LGG	chr2	21011831	Silent	NA	G1679G	0.31
LGG	chr2	21015496	Missense_Mutation	rs72653076	R1128C	0.41
LGG	chr2	21027892	Missense_Mutation	rs755497502	P668L	0.21
LGG	chr2	21006956	Silent	novel	L3304L	0.23
LGG	chr2	21022926	Silent	rs72653068	H907H	0.35
LGG	chr2	21007471	Missense_Mutation	NA	P3133S	0.2
LGG	chr2	21019061	Missense_Mutation	rs149357946	A1018T	0.34
LGG	chr2	21003290	Silent	NA	R4044R	0.3
LGG	chr2	21004341	Silent	NA	A4005A	0.49
LGG	chr2	21007842	Missense_Mutation	NA	L3009Q	0.19
LGG	chr2	21040986	Missense_Mutation	novel	L112W	0.24
LGG	chr2	21008174	Silent	novel	L2898L	0.06
LGG	chr2	21013257	Silent	novel	Y1373Y	0.04
LGG	chr2	21015188	Missense_Mutation	novel	P1194H	0.34
LGG	chr2	21032397	Missense_Mutation	rs776786681	R437C	0.39
LGG	chr2	21005300	Silent	rs542175556	I3856I	0.47
LGG	chr2	21007547	Silent	rs72653101	N3107N	0.42
LGG	chr2	21005434	Missense_Mutation	NA	E3812Q	0.46
LGG	chr2	21007683	Nonsense_Mutation	NA	L3062*	0.08
LGG	chr2	21002269	Missense_Mutation	NA	R4385C	0.39
LGG	chr2	21008043	Missense_Mutation	novel	H2942R	0.07
LGG	chr2	21003285	Missense_Mutation	rs149273387	R4046Q	0.35
LIHC	chr2	21002641	Frame_Shift_Del	novel	*H4260Qfs10**	0.39
LIHC	chr2	21042447	Missense_Mutation	novel	K51E	0.42
LIHC	chr2	21005270	Frame_Shift_Del	novel	*I3862Lfs17**	0.39
LIHC	chr2	21013381	Missense_Mutation	novel	S1332C	0.35
LIHC	chr2	21032402	Missense_Mutation	novel	D435G	0.38
LIHC	chr2	21028367	Frame_Shift_Ins	novel	*I597Yfs53**	0.43
LIHC	chr2	21028475	Missense_Mutation	NA	A561S	0.43
LIHC	chr2	21009121	Frame_Shift_Ins	novel	*Q2583Gfs9**	0.43
LIHC	chr2	21006877	Missense_Mutation	NA	I3331V	0.38
LIHC	chr2	21026923	Silent	NA	A703A	0.52
LIHC	chr2	21005697	Missense_Mutation	novel	K3724R	0.39
LIHC	chr2	21012570	Nonsense_Mutation	NA	S1433*	0.26
LIHC	chr2	21013328	Frame_Shift_Ins	novel	*V1350Sfs45**	0.25
LIHC	chr2	21004284	Missense_Mutation	novel	F4024L	0.4
LIHC	chr2	21008198	Missense_Mutation	NA	F2890L	0.35
LIHC	chr2	21013356	Frame_Shift_Del	novel	*F1340Lfs17**	0.19
LIHC	chr2	21009585	Frame_Shift_Del	novel	*L2427Vfs3**	0.12
LIHC	chr2	21008164	Missense_Mutation	NA	S2902C	0.46
LIHC	chr2	21037123	Missense_Mutation	NA	P224S	0.11
LIHC	chr2	21011948	Frame_Shift_Ins	novel	*H1641Sfs23**	0.45
LIHC	chr2	21006508	Frame_Shift_Ins	novel	*V3454Cfs8**	0.33
LIHC	chr2	21033396	Nonsense_Mutation	novel	Q343*	0.44
LIHC	chr2	21005475	Missense_Mutation	NA	T3798R	0.21
LIHC	chr2	21008329	Frame_Shift_Ins	NA	*G2847Wfs5**	0.4
LIHC	chr2	21044013	5'UTR	novel		0.26
LIHC	chr2	21023536	Nonsense_Mutation	NA	E865*	0.63
LIHC	chr2	21026918	Missense_Mutation	NA	F705S	0.17
LIHC	chr2	21010833	Missense_Mutation	rs749146264	R2012Q	0.31
LIHC	chr2	21006647	Missense_Mutation	novel	E3407D	0.62
LIHC	chr2	21006641	Missense_Mutation	NA	S3409R	0.44
LIHC	chr2	21009253	Frame_Shift_Del	novel	V2539*	0.11
LIHC	chr2	21008198	Missense_Mutation	NA	F2890L	0.38
LIHC	chr2	21016548	Nonsense_Mutation	novel	*T1075Ffs2**	0.43
LIHC	chr2	21006617	Silent	NA	T3417T	0.25
LIHC	chr2	21011073	Frame_Shift_Del	novel	*L1932Rfs2**	0.09
LIHC	chr2	21008274	Frame_Shift_Del	novel	*N2865Ifs9**	0.14
LIHC	chr2	21005990	Silent	NA	T3626T	0.33
LIHC	chr2	21009709	Frame_Shift_Del	novel	*I2386Rfs4**	0.32
LIHC	chr2	21044060	5'UTR	novel		0.58
LIHC	chr2	21007069	Missense_Mutation	novel	M3267L	0.16
LIHC	chr2	21023018	Frame_Shift_Ins	novel	*P877Tfs20**	0.43
LUAD	chr2	21006525	Missense_Mutation	NA	T3448N	0.12
LUAD	chr2	21006703	Missense_Mutation	NA	R3389G	0.15
LUAD	chr2	21007058	Silent	rs138010392	F3270F	0.11
LUAD	chr2	21033432	Missense_Mutation	novel	E331K	0.09
LUAD	chr2	21015371	Splice_Region	rs141763789	Y1169Y	0.36
LUAD	chr2	21016639	Missense_Mutation	novel	Q1044H	0.18
LUAD	chr2	21011117	Silent	NA	L1917L	0.32
LUAD	chr2	21002176	Missense_Mutation	NA	V4416L	0.17
LUAD	chr2	21010349	Missense_Mutation	NA	Q2173H	0.16
LUAD	chr2	21012220	Missense_Mutation	NA	L1550M	0.11
LUAD	chr2	21004354	Missense_Mutation	novel	A4001E	0.24
LUAD	chr2	21007423	Missense_Mutation	NA	D3149Y	0.28
LUAD	chr2	21003289	Missense_Mutation	novel	V4045I	0.05
LUAD	chr2	21003291	Missense_Mutation	novel	R4044M	0.05
LUAD	chr2	21019109	Nonsense_Mutation	novel	E1002*	0.07
LUAD	chr2	21006605	Missense_Mutation	novel	M3421I	0.04
LUAD	chr2	21011288	Missense_Mutation	rs199585500	Q1860H	0.1
LUAD	chr2	21023626	Missense_Mutation	NA	A835P	0.18
LUAD	chr2	21019734	Silent	novel	T996T	0.38
LUAD	chr2	21005726	Silent	NA	P3714P	0.58
LUAD	chr2	21008046	Missense_Mutation	rs768600483	T2941I	0.55
LUAD	chr2	21022926	Silent	rs72653068	H907H	0.11
LUAD	chr2	21002734	Missense_Mutation	novel	Q4230K	0.23
LUAD	chr2	21011846	Missense_Mutation	NA	E1674D	0.19
LUAD	chr2	21008985	Missense_Mutation	novel	S2628L	0.17
LUAD	chr2	21011216	Missense_Mutation	novel	N1884K	0.16
LUAD	chr2	21012426	Missense_Mutation	novel	V1481D	0.25
LUAD	chr2	21015404	Silent	novel	G1158G	0.2
LUAD	chr2	21038018	Silent	novel	G159G	0.06
LUAD	chr2	21034891	Missense_Mutation	NA	G277R	0.17
LUAD	chr2	21003043	Missense_Mutation	rs769785870	D4127N	0.08
LUAD	chr2	21006726	Missense_Mutation	NA	L3381S	0.49
LUAD	chr2	21006509	Silent	novel	T3453T	0.13
LUAD	chr2	21005528	Silent	novel	A3780A	0.09
LUAD	chr2	21027925	Missense_Mutation	NA	G657V	0.11
LUAD	chr2	21010777	Missense_Mutation	novel	S2031C	0.22
LUAD	chr2	21019805	Missense_Mutation	NA	L973M	0.41
LUAD	chr2	21041037	Missense_Mutation	novel	S95I	0.12
LUAD	chr2	21009520	Missense_Mutation	novel	L2450V	0.46
LUAD	chr2	21006915	Missense_Mutation	novel	P3318Q	0.17
LUAD	chr2	21008119	Missense_Mutation	NA	G2917S	0.25
LUAD	chr2	21014510	Missense_Mutation	NA	E1260D	0.27
LUAD	chr2	21011174	Silent	NA	S1898S	0.11
LUAD	chr2	21019860	Silent	NA	P954P	0.09
LUAD	chr2	21004305	Silent	rs12713501	D4017D	0.23
LUAD	chr2	21008046	Missense_Mutation	novel	T2941K	0.19
LUAD	chr2	21029695	Missense_Mutation	novel	L521M	0.29
LUAD	chr2	21004345	Missense_Mutation	NA	P4004Q	0.18
LUAD	chr2	21028519	Missense_Mutation	NA	Q546L	0.21
LUAD	chr2	21012648	Missense_Mutation	novel	S1407F	0.18
LUAD	chr2	21010503	Missense_Mutation	NA	A2122D	0.47
LUAD	chr2	21007408	Frame_Shift_Del	novel	*E3154Kfs5**	0.32
LUAD	chr2	21011097	Missense_Mutation	NA	T1924N	0.3
LUAD	chr2	21028484	Silent	NA	R558R	0.34
LUAD	chr2	21027993	Silent	NA	S634S	0.32
LUAD	chr2	21010756	Missense_Mutation	NA	D2038N	0.33
LUAD	chr2	21027880	Missense_Mutation	NA	M672K	0.16
LUAD	chr2	21013371	Silent	novel	F1335F	0.24
LUAD	chr2	21010000	Nonsense_Mutation	NA	E2290*	0.44
LUAD	chr2	21010828	Missense_Mutation	novel	L2014M	0.14
LUAD	chr2	21012006	Missense_Mutation	novel	S1621Y	0.17
LUAD	chr2	21041034	Missense_Mutation	novel	Q96R	0.15
LUAD	chr2	21011153	Missense_Mutation	rs754036439	M1905I	0.21
LUAD	chr2	21003305	Missense_Mutation	NA	F4039L	0.38
LUAD	chr2	21016458	Missense_Mutation	novel	A1105S	0.06
LUAD	chr2	21006525	Missense_Mutation	NA	T3448N	0.07
LUAD	chr2	21010913	Silent	NA	T1985T	0.06
LUAD	chr2	21006722	Missense_Mutation	novel	E3382D	0.31
LUAD	chr2	21032493	Missense_Mutation	rs61745113	P405T	0.16
LUAD	chr2	21012029	Missense_Mutation	NA	S1613R	0.2
LUAD	chr2	21002583	Missense_Mutation	novel	A4280V	0.08
LUAD	chr2	21009149	Missense_Mutation	novel	W2573C	0.05
LUAD	chr2	21009524	Missense_Mutation	novel	Q2448H	0.2
LUAD	chr2	21032485	Silent	novel	L407L	0.09
LUAD	chr2	21006162	Missense_Mutation	novel	N3569T	0.21
LUAD	chr2	21023030	Missense_Mutation	NA	L873M	0.11
LUAD	chr2	21003110	Silent	rs754600839	L4104L	0.19
LUAD	chr2	21006954	Missense_Mutation	novel	P3305Q	0.2
LUAD	chr2	21013416	Silent	novel	A1320A	0.23
LUAD	chr2	21003146	Missense_Mutation	NA	H4092Q	0.13
LUAD	chr2	21010459	Missense_Mutation	NA	H2137D	0.11
LUAD	chr2	21034833	Missense_Mutation	novel	S296I	0.34
LUAD	chr2	21005895	Missense_Mutation	NA	H3658P	0.69
LUAD	chr2	21009173	Silent	NA	A2565A	0.21
LUAD	chr2	21028526	Missense_Mutation	NA	L544I	0.39
LUAD	chr2	21027916	Missense_Mutation	rs200533347	I660T	0.58
LUAD	chr2	21008266	Missense_Mutation	novel	E2868Q	0.15
LUAD	chr2	21032443	Silent	novel	P421P	0.28
LUAD	chr2	21011585	Silent	NA	G1761G	0.45
LUAD	chr2	21004367	Missense_Mutation	NA	I3997L	0.55
LUAD	chr2	21005695	Missense_Mutation	NA	V3725F	0.09
LUAD	chr2	21011586	Missense_Mutation	NA	G1761V	0.53
LUAD	chr2	21010796	Silent	novel	I2024I	0.14
LUAD	chr2	21006925	Missense_Mutation	novel	L3315I	0.19
LUAD	chr2	21008906	Missense_Mutation	novel	N2654K	0.18
LUAD	chr2	21006365	Missense_Mutation	NA	K3501N	0.24
LUAD	chr2	21010501	Missense_Mutation	novel	N2123Y	0.41
LUAD	chr2	21007525	Missense_Mutation	rs373369264	V3115I	0.15
LUAD	chr2	21005220	Missense_Mutation	novel	L3883Q	0.2
LUAD	chr2	21001838	Silent	NA	Y4528Y	0.22
LUAD	chr2	21008141	Missense_Mutation	NA	E2909D	0.09
LUAD	chr2	21006034	Missense_Mutation	novel	D3612N	0.23
LUAD	chr2	21002591	Silent	novel	S4277S	0.13
LUAD	chr2	21005688	Missense_Mutation	novel	A3727D	0.16
LUAD	chr2	21008530	Missense_Mutation	rs781756323	G2780R	0.69
LUAD	chr2	21025040	Missense_Mutation	novel	L777I	0.17
LUAD	chr2	21032546	Missense_Mutation	novel	Q387P	0.2
LUAD	chr2	21032547	Missense_Mutation	novel	Q387K	0.18
LUAD	chr2	21003049	Missense_Mutation	novel	D4125Y	0.21
LUAD	chr2	21002927	Missense_Mutation	NA	Q4165H	0.14
LUAD	chr2	21012206	Silent	NA	I1554I	0.16
LUAD	chr2	21040941	Missense_Mutation	novel	S127Y	0.36
LUAD	chr2	21012334	Missense_Mutation	NA	G1512C	0.14
LUAD	chr2	21007954	Missense_Mutation	novel	Q2972K	0.15
LUAD	chr2	21013217	Missense_Mutation	NA	A1387P	0.25
LUAD	chr2	21004655	Missense_Mutation	rs766656064	E3937K	0.2
LUAD	chr2	21008094	Missense_Mutation	NA	G2925V	0.17
LUAD	chr2	21011587	Missense_Mutation	NA	G1761S	0.2
LUAD	chr2	21010729	Missense_Mutation	novel	E2047K	0.21
LUAD	chr2	21002942	Silent	novel	G4160G	0.34
LUAD	chr2	21006762	Nonsense_Mutation	novel	S3369*	0.31
LUAD	chr2	21010466	Missense_Mutation	NA	Q2134H	0.1
LUAD	chr2	21009031	Missense_Mutation	NA	Q2613K	0.23
LUAD	chr2	21003325	Missense_Mutation	novel	D4033Y	0.41
LUAD	chr2	21011412	Missense_Mutation	novel	L1819Q	0.47
LUAD	chr2	21006061	Missense_Mutation	NA	H3603N	0.25
LUAD	chr2	21010433	Silent	NA	L2145L	0.37
LUAD	chr2	21002630	Missense_Mutation	NA	D4264E	0.16
LUAD	chr2	21019841	Missense_Mutation	novel	Q961K	0.25
LUAD	chr2	21005569	Missense_Mutation	NA	E3767K	0.17
LUAD	chr2	21012454	Missense_Mutation	NA	D1472Y	0.45
LUAD	chr2	21010822	Missense_Mutation	rs755811872	D2016Y	0.32
LUAD	chr2	21010760	Silent	novel	I2036I	0.17
LUAD	chr2	21011723	Missense_Mutation	novel	Q1715H	0.22
LUAD	chr2	21019038	Missense_Mutation	novel	E1025D	0.46
LUAD	chr2	21013304	Missense_Mutation	novel	L1358I	0.27
LUAD	chr2	21005350	Silent	NA	L3840L	0.07
LUAD	chr2	21019805	Missense_Mutation	NA	L973M	0.16
LUAD	chr2	21007334	Missense_Mutation	NA	K3178N	0.29
LUAD	chr2	21023525	Missense_Mutation	NA	N868K	0.25
LUAD	chr2	21037977	Missense_Mutation	NA	A173D	0.22
LUAD	chr2	21005780	Missense_Mutation	novel	I3696M	0.22
LUAD	chr2	21007578	Missense_Mutation	novel	K3097R	0.24
LUAD	chr2	21034854	Missense_Mutation	rs372790791	E289G	0.15
LUAD	chr2	21011791	Missense_Mutation	novel	H1693N	0.12
LUAD	chr2	21006403	Missense_Mutation	novel	Y3489H	0.06
LUAD	chr2	21007110	Missense_Mutation	novel	V3253A	0.25
LUAD	chr2	21012232	Missense_Mutation	NA	S1546P	0.53
LUAD	chr2	21006333	Missense_Mutation	rs145861016	T3512N	0.4
LUAD	chr2	21012286	Nonsense_Mutation	novel	Q1528*	0.36
LUAD	chr2	21011424	Missense_Mutation	NA	R1815L	0.37
LUAD	chr2	21013345	Missense_Mutation	novel	K1344M	0.35
LUAD	chr2	21022921	Nonsense_Mutation	NA	S909*	0.14
LUAD	chr2	21011570	Missense_Mutation	NA	F1766L	0.26
LUSC	chr2	21009872	Missense_Mutation	novel	E2332D	0.42
LUSC	chr2	21034813	Splice_Region	novel		0.35
LUSC	chr2	21015121	Silent	NA	V1216V	0.27
LUSC	chr2	21009793	Missense_Mutation	novel	D2359H	0.31
LUSC	chr2	21033313	Silent	NA	L370L	0.13
LUSC	chr2	21004404	Silent	NA	T3984T	0.17
LUSC	chr2	21008348	Silent	novel	G2840G	0.09
LUSC	chr2	21027943	Missense_Mutation	NA	A651V	0.14
LUSC	chr2	21032493	Missense_Mutation	novel	P405S	0.27
LUSC	chr2	21007186	Frame_Shift_Del	novel	*I3228Lfs38**	0.24
LUSC	chr2	21025104	Missense_Mutation	novel	M755I	0.23
LUSC	chr2	21009727	Silent	NA	L2381L	0.18
LUSC	chr2	21006452	Silent	NA	T3472T	0.28
LUSC	chr2	21010988	Silent	NA	I1960I	0.44
LUSC	chr2	21015094	Missense_Mutation	novel	H1225Q	0.19
LUSC	chr2	21009874	Missense_Mutation	NA	E2332K	0.12
LUSC	chr2	21008811	Nonsense_Mutation	NA	W2686*	0.18
LUSC	chr2	21024959	Missense_Mutation	rs749308859	R804C	0.14
LUSC	chr2	21010722	Missense_Mutation	novel	P2049R	0.08
LUSC	chr2	21010723	Missense_Mutation	novel	P2049A	0.09
LUSC	chr2	21019062	Missense_Mutation	novel	S1017R	0.19
LUSC	chr2	21002845	Missense_Mutation	novel	L4193V	0.22
LUSC	chr2	21003097	Missense_Mutation	novel	Q4109K	0.56
LUSC	chr2	21013184	Missense_Mutation	novel	D1398Y	0.27
LUSC	chr2	21013235	Missense_Mutation	novel	D1381H	0.19
LUSC	chr2	21009814	Nonsense_Mutation	novel	Q2352*	0.21
LUSC	chr2	21009815	Silent	novel	D2351D	0.22
LUSC	chr2	21022929	Silent	novel	F906F	0.16
LUSC	chr2	21012486	Missense_Mutation	novel	W1461L	0.21
LUSC	chr2	21006026	Silent	NA	P3614P	0.22
LUSC	chr2	21013353	Silent	NA	T1341T	0.29
LUSC	chr2	21004629	Silent	novel	T3945T	0.38
LUSC	chr2	21029939	Missense_Mutation	novel	D477H	0.05
LUSC	chr2	21011458	Missense_Mutation	NA	N1804D	0.14
LUSC	chr2	21006807	Missense_Mutation	novel	A3354D	0.18
LUSC	chr2	21009229	Missense_Mutation	novel	V2547L	0.18
LUSC	chr2	21016645	Silent	rs547789079	A1042A	0.15
LUSC	chr2	21005193	Missense_Mutation	novel	P3892L	0.34
LUSC	chr2	21005629	Missense_Mutation	NA	P3747A	0.19
LUSC	chr2	21019831	Nonsense_Mutation	novel	S964*	0.33
LUSC	chr2	21005962	Missense_Mutation	novel	E3636K	0.11
LUSC	chr2	21008725	Nonsense_Mutation	novel	E2715*	0.06
LUSC	chr2	21037230	Missense_Mutation	novel	T188I	0.5
LUSC	chr2	21011916	Missense_Mutation	novel	G1651V	0.3
LUSC	chr2	21009310	Nonsense_Mutation	rs746483297	R2520*	0.34
LUSC	chr2	21001647	3'UTR	novel		0.18
LUSC	chr2	21011147	Silent	rs755014418	I1907I	0.06
LUSC	chr2	21005503	Missense_Mutation	rs752262589	V3789I	0.18
LUSC	chr2	21003161	Missense_Mutation	NA	K4087N	0.34
LUSC	chr2	21033360	Silent	NA	L355L	0.51
LUSC	chr2	21008028	Missense_Mutation	rs183475426	S2947T	0.34
LUSC	chr2	21011443	Missense_Mutation	novel	T1809S	0.28
LUSC	chr2	21028441	Missense_Mutation	novel	A572E	0.26
LUSC	chr2	21010645	Missense_Mutation	novel	E2075Q	0.47
LUSC	chr2	21006314	Missense_Mutation	novel	N3518K	0.26
LUSC	chr2	21028488	Missense_Mutation	novel	D556E	0.27
LUSC	chr2	21012484	Missense_Mutation	NA	G1462R	0.1
LUSC	chr2	21025124	Missense_Mutation	novel	D749Y	0.22
LUSC	chr2	21011094	Missense_Mutation	novel	G1925V	0.08
LUSC	chr2	21003160	Missense_Mutation	novel	Y4088N	0.15
LUSC	chr2	21010005	Missense_Mutation	NA	H2288L	0.16
LUSC	chr2	21026862	Missense_Mutation	rs143425834	G724C	0.21
LUSC	chr2	21002847	Nonsense_Mutation	novel	S4192*	0.11
LUSC	chr2	21008009	Silent	NA	P2953P	0.12
LUSC	chr2	21009011	Silent	rs762465145	V2619V	0.24
LUSC	chr2	21007256	Missense_Mutation	NA	F3204L	0.17
LUSC	chr2	21014500	Missense_Mutation	novel	Q1264K	0.67
LUSC	chr2	21011563	Missense_Mutation	novel	K1769E	0.61
LUSC	chr2	21029723	Silent	rs1041952	L511L	0.11
LUSC	chr2	21009878	Silent	novel	V2330V	0.41
LUSC	chr2	21026830	Missense_Mutation	novel	L734F	0.45
LUSC	chr2	21002546	Silent	rs546024019	T4292T	0.26
LUSC	chr2	21009331	Nonsense_Mutation	rs146538280	R2513*	0.39
LUSC	chr2	21009652	Nonsense_Mutation	NA	E2406*	0.24
LUSC	chr2	21012026	Silent	novel	L1614L	0.24
LUSC	chr2	21025113	Silent	novel	N752N	0.19
LUSC	chr2	21007164	Missense_Mutation	NA	A3235D	0.32
LUSC	chr2	21002875	Missense_Mutation	novel	H4183N	0.22
LUSC	chr2	21025008	Silent	NA	A787A	0.28
LUSC	chr2	21041020	Missense_Mutation	novel	E101Q	0.39
LUSC	chr2	21010597	Missense_Mutation	rs757141693	V2091L	0.28
LUSC	chr2	21005361	Missense_Mutation	novel	A3836V	0.27
LUSC	chr2	21023552	Missense_Mutation	NA	K859N	0.11
LUSC	chr2	21011986	Missense_Mutation	novel	A1628S	0.45
LUSC	chr2	21012469	Missense_Mutation	novel	A1467P	0.18
LUSC	chr2	21025032	Silent	novel	I779I	0.26
LUSC	chr2	21029672	Silent	novel	I528I	0.23
LUSC	chr2	21010137	Missense_Mutation	NA	S2244I	0.33
LUSC	chr2	21029949	Silent	NA	Q473Q	0.15
LUSC	chr2	21002074	Missense_Mutation	novel	E4450K	0.18
LUSC	chr2	21005529	Missense_Mutation	NA	A3780D	0.31
LUSC	chr2	21005880	Missense_Mutation	rs267599179	G3663E	0.27
LUSC	chr2	21007608	Missense_Mutation	NA	W3087L	0.16
LUSC	chr2	21032573	Missense_Mutation	NA	T378I	0.47
LUSC	chr2	21013434	Missense_Mutation	novel	E1314D	0.47
LUSC	chr2	21005506	Missense_Mutation	rs13306191	E3788K	0.24
LUSC	chr2	21032575	Silent	novel	I377I	0.39
LUSC	chr2	21006961	Nonsense_Mutation	NA	E3303*	0.26
LUSC	chr2	21011705	Silent	rs536182427	V1721V	0.19
LUSC	chr2	21019731	Silent	NA	G997G	0.14
LUSC	chr2	21027992	Missense_Mutation	rs548108916	R635W	0.21
LUSC	chr2	21001858	Missense_Mutation	rs767091894	D4522Y	0.1
LUSC	chr2	21001859	Silent	novel	I4521I	0.11
LUSC	chr2	21027926	Missense_Mutation	novel	G657W	0.5
LUSC	chr2	21007285	Missense_Mutation	NA	E3195Q	0.23
LUSC	chr2	21011084	Silent	novel	Y1928Y	0.08
LUSC	chr2	21009049	Missense_Mutation	NA	L2607V	0.32
LUSC	chr2	21016448	Missense_Mutation	rs763870199	G1108D	0.67
LUSC	chr2	21011585	Silent	novel	G1761G	0.17
LUSC	chr2	21002753	Silent	novel	E4223E	0.2
LUSC	chr2	21028364	Missense_Mutation	novel	A598S	0.15
LUSC	chr2	21033487	Missense_Mutation	novel	S312R	0.5
LUSC	chr2	21015093	Missense_Mutation	novel	V1226L	0.15
LUSC	chr2	21009958	Missense_Mutation	NA	T2304A	0.11
LUSC	chr2	21011907	Missense_Mutation	novel	T1654N	0.21
LUSC	chr2	21001994	Silent	novel	I4476I	0.26
LUSC	chr2	21006996	Missense_Mutation	rs747787527	R3291H	0.26
LUSC	chr2	21007674	Missense_Mutation	novel	T3065I	0.35
LUSC	chr2	21006423	Missense_Mutation	novel	S3482N	0.14
LUSC	chr2	21034843	Missense_Mutation	novel	K293E	0.27
OV	chr2	21010641	Missense_Mutation	novel	T2076S	0.05
OV	chr2	21007084	Missense_Mutation	NA	P3262S	0.12
OV	chr2	21007606	Missense_Mutation	NA	Q3088K	0.55
OV	chr2	21012550	Missense_Mutation	NA	V1440L	0.13
OV	chr2	21009770	Silent	novel	H2366H	0.14
OV	chr2	21010772	Nonsense_Mutation	novel	*E2032Dfs7**	0.12
OV	chr2	21011204	Frame_Shift_Ins	novel	*S1889Afs52**	0.08
OV	chr2	21029652	In_Frame_Ins	novel	E535delinsANFNK	0.04
OV	chr2	21029653	Frame_Shift_Ins	novel	*E535Ffs4**	0.02
OV	chr2	21038042	Silent	NA	T151T	0.23
OV	chr2	21006456	Missense_Mutation	novel	S3471C	0.15
OV	chr2	21002356	Missense_Mutation	novel	L4356V	0.38
OV	chr2	21010961	Frame_Shift_Ins	novel	*S1969Rfs50**	0.08
OV	chr2	21010214	Silent	NA	I2218I	0.15
OV	chr2	21012613	Missense_Mutation	NA	T1419A	0.27
OV	chr2	21040992	In_Frame_Del	NA	N106_G109del	0.74
OV	chr2	21019024	Missense_Mutation	NA	V1030G	0.14
OV	chr2	21016603	Silent	rs760548142	Q1056Q	0.04
OV	chr2	21002085	Missense_Mutation	rs769871675	R4446T	0.18
OV	chr2	21011910	Missense_Mutation	NA	S1653Y	0.09
OV	chr2	21012288	Missense_Mutation	NA	L1527H	0.11
OV	chr2	21006524	Silent	rs13306193	T3448T	0.92
OV	chr2	21007201	Missense_Mutation	NA	Y3223H	0.09
OV	chr2	21002624	Missense_Mutation	NA	I4266M	0.18
OV	chr2	21007999	Missense_Mutation	NA	F2957I	0.11
OV	chr2	21003275	Missense_Mutation	NA	D4049E	0.21
OV	chr2	21005982	Missense_Mutation	novel	Q3629L	0.06
OV	chr2	21010328	Silent	NA	Q2180Q	0.42
OV	chr2	21035676	Silent	NA	S242S	0.11
OV	chr2	21003083	Frame_Shift_Del	NA	*R4105Sfs16**	0.41
OV	chr2	21002916	Missense_Mutation	NA	D4169V	0.47
OV	chr2	21009081	Missense_Mutation	NA	T2596S	0.27
OV	chr2	21037103	Silent	rs151096846	G230G	0.48
OV	chr2	21037163	Silent	NA	G210G	0.24
OV	chr2	21012292	Missense_Mutation	novel	Y1526H	0.12
OV	chr2	21016623	In_Frame_Del	novel	K1043_M1049del	0.04
OV	chr2	21007510	Nonsense_Mutation	novel	E3120*	0.07
OV	chr2	21013386	Frame_Shift_Ins	novel	*P1331Gfs27**	0.03
OV	chr2	21022874	Missense_Mutation	novel	I925F	0.05
OV	chr2	21003048	Missense_Mutation	novel	D4125V	0.27
OV	chr2	21032430	Missense_Mutation	novel	L426M	0.09
OV	chr2	21027898	Missense_Mutation	novel	Y666F	0.06
OV	chr2	21006635	Missense_Mutation	rs771372599	N3411K	0.04
OV	chr2	21007197	Frame_Shift_Ins	novel	*N3224Tfs50**	0.31
OV	chr2	21005987	Missense_Mutation	NA	K3627N	0.34
OV	chr2	21010283	Silent	NA	K2195K	0.16
OV	chr2	21002755	Missense_Mutation	NA	E4223Q	0.18
PAAD	chr2	21011675	Silent	rs775515832	V1731V	0.05
PAAD	chr2	21002797	Missense_Mutation	novel	G4209R	0.13
PAAD	chr2	21015472	Nonsense_Mutation	novel	E1136*	0.07
PAAD	chr2	21001847	Missense_Mutation	novel	I4525M	0.03
PAAD	chr2	21010394	Silent	novel	I2158I	0.28
PAAD	chr2	21010976	Silent	novel	L1964L	0.28
PAAD	chr2	21013248	Silent	novel	G1376G	0.24
PAAD	chr2	21015446	Silent	novel	A1144A	0.17
PAAD	chr2	21022909	Missense_Mutation	novel	A913D	0.1
PAAD	chr2	21027992	Missense_Mutation	rs548108916	R635W	0.16
PAAD	chr2	21028367	Missense_Mutation	novel	I597V	0.05
PAAD	chr2	21011037	Missense_Mutation	novel	H1944R	0.04
PAAD	chr2	21001691	3'UTR	novel		0.13
PAAD	chr2	21027991	Missense_Mutation	rs202001155	R635Q	0.21
PCPG	chr2	21006812	Silent	rs369022661	T3352T	0.39
PRAD	chr2	21029955	Missense_Mutation	NA	M471I	0.08
PRAD	chr2	21010030	Missense_Mutation	NA	H2280Y	0.29
PRAD	chr2	21010212	Missense_Mutation	rs200106845	R2219H	0.3
PRAD	chr2	21037125	Missense_Mutation	novel	S223N	0.08
PRAD	chr2	21037126	Missense_Mutation	novel	S223R	0.07
PRAD	chr2	21008439	Missense_Mutation	NA	A2810E	0.26
PRAD	chr2	21026902	Silent	novel	F710F	0.19
PRAD	chr2	21010834	Nonsense_Mutation	rs147863759	R2012*	0.23
PRAD	chr2	21005507	Silent	rs200979977	P3787P	0.47
PRAD	chr2	21003181	Missense_Mutation	novel	L4081I	0.47
PRAD	chr2	21009105	Missense_Mutation	rs781471544	P2588H	0.45
READ	chr2	21002723	Silent	rs56675344	S4233S	0.14
READ	chr2	21005956	Missense_Mutation	rs61744151	R3638W	0.21
READ	chr2	21009480	Missense_Mutation	NA	A2463V	0.23
READ	chr2	21013533	Splice_Region	rs72653079	S1281S	0.39
READ	chr2	21028401	Missense_Mutation	NA	Q585H	0.28
READ	chr2	21002068	Missense_Mutation	novel	L4452I	0.14
READ	chr2	21004616	Missense_Mutation	novel	A3950S	0.52
READ	chr2	21009330	Missense_Mutation	rs554045156	R2513Q	0.47
READ	chr2	21012330	Missense_Mutation	rs780817600	R1513Q	0.1
READ	chr2	21029651	Silent	rs763856498	E535E	0.27
READ	chr2	21001725	3'UTR	novel		0.04
READ	chr2	21009706	Missense_Mutation	novel	D2388Y	0.04
READ	chr2	21006196	Missense_Mutation	rs12713559	R3558C	0.83
READ	chr2	21008664	Missense_Mutation	novel	D2735A	0.36
READ	chr2	21005390	Silent	novel	T3826T	0.43
READ	chr2	21006355	Missense_Mutation	NA	L3505I	0.45
READ	chr2	21007761	Missense_Mutation	NA	S3036Y	0.46
READ	chr2	21010733	Silent	novel	A2045A	0.36
READ	chr2	21011252	Silent	NA	I1872I	0.42
READ	chr2	21013379	Nonsense_Mutation	rs121918383	R1333*	0.29
READ	chr2	21015138	Missense_Mutation	novel	L1211I	0.06
READ	chr2	21028484	Nonsense_Mutation	novel	R558*	0.36
READ	chr2	21042470	Missense_Mutation	NA	A43V	0.31
READ	chr2	21007858	Missense_Mutation	novel	A3004S	0.15
READ	chr2	21015464	Silent	rs140456702	L1138L	0.63
READ	chr2	21002300	Silent	novel	L4374L	0.08
READ	chr2	21002833	Missense_Mutation	NA	L4197M	0.39
READ	chr2	21003162	Missense_Mutation	NA	K4087M	0.26
READ	chr2	21007423	Missense_Mutation	NA	D3149Y	0.32
READ	chr2	21009109	Missense_Mutation	rs375855688	V2587L	0.28
READ	chr2	21011001	Missense_Mutation	NA	S1956Y	0.24
READ	chr2	21011245	Silent	NA	L1875L	0.21
READ	chr2	21019077	Silent	novel	E1012E	0.47
READ	chr2	21042446	Missense_Mutation	rs764776276	K51R	0.2
SARC	chr2	21009124	Frame_Shift_Del	novel	*E2582Sfs37**	0.92
SARC	chr2	21009126	Missense_Mutation	novel	V2581E	0.92
SARC	chr2	21025041	Nonsense_Mutation	novel	Y776*	0.32
SARC	chr2	21005624	Silent	rs72654406	T3748T	0.83
SARC	chr2	21011700	Missense_Mutation	rs570383610	S1723I	0.09
SARC	chr2	21006882	Missense_Mutation	novel	I3329T	0.15
SARC	chr2	21002379	Missense_Mutation	novel	L4348S	0.07
SARC	chr2	21011069	Silent	novel	L1933L	0.36
SARC	chr2	21012343	Missense_Mutation	NA	P1509S	0.32
SARC	chr2	21022872	Silent	NA	I925I	0.13
SARC	chr2	21011293	Missense_Mutation	rs770773955	V1859F	0.11
SARC	chr2	21005533	Missense_Mutation	novel	F3779L	0.5
SARC	chr2	21019720	Splice_Region	novel		0.72
SARC	chr2	21033360	Missense_Mutation	novel	L355M	0.19
SARC	chr2	21012322	Missense_Mutation	novel	G1516R	0.15
SARC	chr2	21015253	Silent	novel	E1172E	0.12
SARC	chr2	21023607	Missense_Mutation	novel	G841E	0.23
SKCM	chr2	21007728	Missense_Mutation	rs61742323	T3047M	0.23
SKCM	chr2	21008396	Silent	NA	L2824L	0.28
SKCM	chr2	21013214	Missense_Mutation	rs267599185	R1388C	0.34
SKCM	chr2	21032452	Silent	NA	I418I	0.26
SKCM	chr2	21002656	Missense_Mutation	rs61743313	E4256K	0.46
SKCM	chr2	21008254	Missense_Mutation	rs267599182	G2872R	0.5
SKCM	chr2	21012570	Missense_Mutation	rs200708197	S1433L	0.22
SKCM	chr2	21008281	Missense_Mutation	NA	E2863K	0.42
SKCM	chr2	21002807	Silent	rs202247483	P4205P	0.49
SKCM	chr2	21009032	Silent	NA	F2612F	0.19
SKCM	chr2	21008617	Missense_Mutation	rs201985284	E2751K	0.37
SKCM	chr2	21009499	Silent	NA	L2457L	0.34
SKCM	chr2	21011927	Missense_Mutation	NA	I1647M	0.4
SKCM	chr2	21012319	Missense_Mutation	NA	E1517K	0.2
SKCM	chr2	21013214	Missense_Mutation	rs267599185	R1388C	0.05
SKCM	chr2	21001813	Missense_Mutation	NA	E4537K	0.65
SKCM	chr2	21007023	Missense_Mutation	NA	S3282N	0.68
SKCM	chr2	21007929	Missense_Mutation	NA	S2980F	0.68
SKCM	chr2	21027935	Nonsense_Mutation	NA	K654*	0.67
SKCM	chr2	21008089	Missense_Mutation	NA	G2927W	0.34
SKCM	chr2	21009103	Missense_Mutation	novel	E2589K	0.2
SKCM	chr2	21009641	Frame_Shift_Del	novel	*F2409Lfs15**	0.3
SKCM	chr2	21014588	Missense_Mutation	novel	M1234I	0.32
SKCM	chr2	21015504	Missense_Mutation	novel	S1125F	0.15
SKCM	chr2	21035601	Silent	rs746672223	F267F	0.08
SKCM	chr2	21006807	Missense_Mutation	NA	A3354V	0.25
SKCM	chr2	21008944	Missense_Mutation	NA	P2642S	0.25
SKCM	chr2	21007399	Missense_Mutation	NA	G3157S	0.31
SKCM	chr2	21011108	Nonsense_Mutation	NA	W1920*	0.33
SKCM	chr2	21006813	Missense_Mutation	rs767624020	T3352I	0.28
SKCM	chr2	21008803	Missense_Mutation	NA	P2689S	0.31
SKCM	chr2	21011665	Missense_Mutation	NA	G1735R	0.35
SKCM	chr2	21006494	Missense_Mutation	NA	M3458I	0.43
SKCM	chr2	21009118	Missense_Mutation	novel	G2584R	0.46
SKCM	chr2	21008479	Missense_Mutation	NA	G2797R	0.33
SKCM	chr2	21009755	Silent	novel	K2371K	0.32
SKCM	chr2	21011123	Silent	NA	G1915G	0.43
SKCM	chr2	21013214	Missense_Mutation	rs267599185	R1388C	0.23
SKCM	chr2	21004297	Missense_Mutation	novel	S4020F	0.2
SKCM	chr2	21005441	Silent	rs770020211	P3809P	0.27
SKCM	chr2	21008561	Silent	NA	F2769F	0.23
SKCM	chr2	21015242	Missense_Mutation	novel	F1176S	0.42
SKCM	chr2	21005893	Missense_Mutation	NA	L3659F	0.37
SKCM	chr2	21012390	Missense_Mutation	NA	S1493F	0.17
SKCM	chr2	21002977	Nonsense_Mutation	novel	Q4149*	0.32
SKCM	chr2	21011192	Silent	novel	F1892F	0.33
SKCM	chr2	21008143	Missense_Mutation	rs200824333	E2909K	0.25
SKCM	chr2	21006351	Missense_Mutation	NA	S3506F	0.13
SKCM	chr2	21019058	Missense_Mutation	novel	T1019A	0.38
SKCM	chr2	21022929	Silent	novel	F906F	0.33
SKCM	chr2	21007804	Missense_Mutation	NA	D3022N	0.38
SKCM	chr2	21013392	Silent	NA	F1328F	0.33
SKCM	chr2	21028412	Missense_Mutation	NA	P582S	0.08
SKCM	chr2	21006178	Missense_Mutation	novel	E3564K	0.59
SKCM	chr2	21010088	Silent	NA	I2260I	0.61
SKCM	chr2	21008078	Missense_Mutation	NA	K2930N	0.45
SKCM	chr2	21008471	Silent	NA	S2799S	0.41
SKCM	chr2	21011432	Silent	NA	G1812G	0.3
SKCM	chr2	21011621	Missense_Mutation	NA	M1749I	0.43
SKCM	chr2	21010189	Missense_Mutation	NA	H2227Y	0.68
SKCM	chr2	21012476	Silent	NA	Q1464Q	0.68
SKCM	chr2	21007303	Missense_Mutation	NA	P3189S	0.23
SKCM	chr2	21022872	Silent	NA	I925I	0.22
SKCM	chr2	21009701	Silent	novel	Y2389Y	0.37
SKCM	chr2	21005686	Missense_Mutation	NA	D3728N	0.46
SKCM	chr2	21013392	Silent	NA	F1328F	0.44
SKCM	chr2	21001647	3'UTR	novel		0.23
SKCM	chr2	21002656	Missense_Mutation	rs61743313	E4256K	0.27
SKCM	chr2	21002804	Silent	NA	G4206G	0.29
SKCM	chr2	21002950	Nonsense_Mutation	novel	Q4158*	0.33
SKCM	chr2	21003070	Missense_Mutation	novel	G4118R	0.37
SKCM	chr2	21005704	Missense_Mutation	novel	P3722S	0.31
SKCM	chr2	21006578	Missense_Mutation	novel	K3430N	0.24
SKCM	chr2	21012110	Silent	NA	K1586K	0.38
SKCM	chr2	21028053	Silent	novel	L614L	0.08
SKCM	chr2	21002250	Missense_Mutation	rs544303971	P4391L	0.33
SKCM	chr2	21002566	Missense_Mutation	NA	A4286T	0.28
SKCM	chr2	21005124	Missense_Mutation	rs201990496	S3915F	0.29
SKCM	chr2	21006186	Missense_Mutation	NA	S3561F	0.29
SKCM	chr2	21006363	Missense_Mutation	NA	G3502D	0.33
SKCM	chr2	21006834	Missense_Mutation	rs746369330	S3345L	0.25
SKCM	chr2	21007045	Missense_Mutation	NA	P3275S	0.26
SKCM	chr2	21007136	Silent	NA	R3244R	0.23
SKCM	chr2	21007700	Silent	NA	L3056L	0.26
SKCM	chr2	21008022	Missense_Mutation	NA	T2949I	0.24
SKCM	chr2	21008501	Silent	rs149734450	I2789I	0.38
SKCM	chr2	21008705	Silent	rs754251948	F2721F	0.28
SKCM	chr2	21009684	Missense_Mutation	NA	G2395E	0.24
SKCM	chr2	21010213	Missense_Mutation	rs141641980	R2219C	0.18
SKCM	chr2	21010521	Missense_Mutation	NA	G2116E	0.27
SKCM	chr2	21010614	Missense_Mutation	rs376782361	R2085Q	0.22
SKCM	chr2	21010897	Missense_Mutation	NA	E1991K	0.26
SKCM	chr2	21011325	Missense_Mutation	NA	S1848L	0.1
SKCM	chr2	21011897	Silent	NA	T1657T	0.2
SKCM	chr2	21012019	Missense_Mutation	NA	G1617R	0.29
SKCM	chr2	21012460	Missense_Mutation	NA	H1470Y	0.25
SKCM	chr2	21012614	Silent	NA	F1418F	0.29
SKCM	chr2	21026842	Silent	NA	V730V	0.27
SKCM	chr2	21028473	Silent	NA	A561A	0.13
SKCM	chr2	21029928	Silent	NA	G480G	0.24
SKCM	chr2	21032534	Missense_Mutation	rs780083904	S391F	0.33
SKCM	chr2	21042373	Silent	NA	R75R	0.28
SKCM	chr2	21002648	Silent	NA	R4258R	0.24
SKCM	chr2	21005089	Missense_Mutation	NA	E3927K	0.26
SKCM	chr2	21007693	Missense_Mutation	rs146377316	R3059C	0.24
SKCM	chr2	21008662	Missense_Mutation	NA	L2736F	0.56
SKCM	chr2	21006253	Missense_Mutation	NA	D3539N	0.41
SKCM	chr2	21008944	Missense_Mutation	NA	P2642S	0.49
SKCM	chr2	21037256	Splice_Site	NA	X180_splice	0.42
SKCM	chr2	21007079	Silent	rs564227456	F3263F	0.21
SKCM	chr2	21038059	Missense_Mutation	NA	E146K	0.45
SKCM	chr2	21014554	Missense_Mutation	NA	P1246T	0.3
SKCM	chr2	21001695	3'UTR	novel		0.55
SKCM	chr2	21008013	Missense_Mutation	novel	G2952E	0.55
SKCM	chr2	21008534	Silent	rs142056660	G2778G	0.26
SKCM	chr2	21011034	Missense_Mutation	novel	D1945A	0.45
SKCM	chr2	21004288	Missense_Mutation	novel	N4023S	0.34
SKCM	chr2	21011325	Missense_Mutation	NA	S1848L	0.42
SKCM	chr2	21009267	Missense_Mutation	NA	R2534Q	0.25
SKCM	chr2	21025101	Silent	rs181882915	L756L	0.11
SKCM	chr2	21007929	Missense_Mutation	NA	S2980F	0.21
SKCM	chr2	21010633	Missense_Mutation	NA	E2079K	0.24
SKCM	chr2	21011465	Silent	rs149787297	L1801L	0.21
SKCM	chr2	21022944	Missense_Mutation	NA	M901I	0.37
SKCM	chr2	21023659	Missense_Mutation	NA	D824N	0.38
SKCM	chr2	21001999	Missense_Mutation	NA	E4475K	0.18
SKCM	chr2	21002986	Missense_Mutation	rs778195760	D4146N	0.24
SKCM	chr2	21008237	Silent	NA	I2877I	0.28
SKCM	chr2	21011449	Missense_Mutation	rs763043332	D1807N	0.31
SKCM	chr2	21011621	Missense_Mutation	NA	M1749I	0.3
SKCM	chr2	21012601	Missense_Mutation	NA	D1423N	0.32
SKCM	chr2	21005877	Missense_Mutation	novel	S3664F	0.56
SKCM	chr2	21007017	Missense_Mutation	NA	S3284F	0.33
SKCM	chr2	21007442	Silent	novel	I3142I	0.52
SKCM	chr2	21006067	Nonsense_Mutation	novel	Q3601*	0.33
SKCM	chr2	21009389	Silent	novel	I2493I	0.31
SKCM	chr2	21014528	Silent	novel	H1254H	0.36
SKCM	chr2	21038081	Silent	NA	G138G	0.17
SKCM	chr2	21004441	Missense_Mutation	NA	G3972E	0.37
SKCM	chr2	21016550	Missense_Mutation	NA	G1074E	0.36
SKCM	chr2	21028371	Silent	novel	S595S	0.31
SKCM	chr2	21006680	Silent	rs763860765	A3396A	0.37
SKCM	chr2	21009611	Silent	novel	F2419F	0.36
SKCM	chr2	21028010	Missense_Mutation	NA	D629N	0.27
SKCM	chr2	21002611	Missense_Mutation	NA	E4271K	0.71
SKCM	chr2	21002716	Missense_Mutation	NA	H4236Y	0.73
SKCM	chr2	21006987	Missense_Mutation	NA	S3294L	0.16
SKCM	chr2	21007203	Missense_Mutation	NA	S3222F	0.4
SKCM	chr2	21007501	Silent	rs770539788	L3123L	0.76
SKCM	chr2	21008081	Nonsense_Mutation	NA	W2929*	0.17
SKCM	chr2	21008940	Missense_Mutation	NA	S2643F	0.17
SKCM	chr2	21010634	Silent	NA	Q2078Q	0.77
SKCM	chr2	21038086	Missense_Mutation	NA	E137K	0.45
SKCM	chr2	21037171	Missense_Mutation	novel	D208N	0.38
SKCM	chr2	21012169	Missense_Mutation	rs570097888	E1567K	0.33
SKCM	chr2	21005936	Silent	NA	F3644F	0.35
SKCM	chr2	21012188	Silent	NA	S1560S	0.3
SKCM	chr2	21009963	Missense_Mutation	NA	G2302E	0.39
SKCM	chr2	21002724	Missense_Mutation	rs377125320	S4233L	0.09
SKCM	chr2	21007757	Silent	NA	L3037L	0.13
SKCM	chr2	21014544	Missense_Mutation	NA	Q1249P	0.24
SKCM	chr2	21016467	Missense_Mutation	NA	T1102S	0.62
SKCM	chr2	21010334	Missense_Mutation	NA	M2178I	0.22
SKCM	chr2	21012167	Silent	NA	E1567E	0.26
SKCM	chr2	21004317	Missense_Mutation	NA	M4013I	0.24
SKCM	chr2	21026951	Missense_Mutation	NA	G694E	0.3
SKCM	chr2	21013224	Silent	NA	S1384S	0.3
SKCM	chr2	21003175	Missense_Mutation	rs762211836	D4083N	0.15
SKCM	chr2	21008512	Missense_Mutation	rs373774326	E2786K	0.12
SKCM	chr2	21011236	Missense_Mutation	novel	A1878T	0.18
SKCM	chr2	21002930	Silent	NA	F4164F	0.27
SKCM	chr2	21006186	Missense_Mutation	NA	S3561F	0.21
SKCM	chr2	21007129	Nonsense_Mutation	NA	Q3247*	0.45
SKCM	chr2	21007471	Missense_Mutation	NA	P3133S	0.19
SKCM	chr2	21011643	Missense_Mutation	NA	M1742T	0.24
SKCM	chr2	21011917	Missense_Mutation	rs748424949	G1651R	0.37
SKCM	chr2	21002121	Missense_Mutation	NA	S4434Y	0.15
SKCM	chr2	21006124	Missense_Mutation	NA	E3582K	0.09
SKCM	chr2	21033460	Silent	novel	Q321Q	0.55
SKCM	chr2	21002263	Missense_Mutation	NA	E4387K	0.3
SKCM	chr2	21007836	Missense_Mutation	rs772266350	G3011E	0.31
SKCM	chr2	21001695	3'UTR	novel		0.37
SKCM	chr2	21011470	Missense_Mutation	NA	D1800N	0.35
SKCM	chr2	21007903	Nonsense_Mutation	NA	Q2989*	0.32
SKCM	chr2	21006493	Missense_Mutation	novel	E3459K	0.26
SKCM	chr2	21006494	Missense_Mutation	NA	M3458I	0.28
SKCM	chr2	21008780	Silent	rs760919952	L2696L	0.22
SKCM	chr2	21007340	Silent	NA	Q3176Q	0.39
SKCM	chr2	21023014	Missense_Mutation	NA	S878F	0.49
SKCM	chr2	21001935	Missense_Mutation	novel	R4496K	0.43
SKCM	chr2	21005194	Missense_Mutation	novel	P3892S	0.39
SKCM	chr2	21008561	Silent	NA	F2769F	0.34
SKCM	chr2	21008774	Silent	novel	V2698V	0.4
SKCM	chr2	21013203	Missense_Mutation	NA	M1391I	0.34
SKCM	chr2	21007390	Missense_Mutation	NA	E3160K	0.25
SKCM	chr2	21012146	Silent	NA	T1574T	0.46
SKCM	chr2	21026914	Silent	NA	G706G	0.23
SKCM	chr2	21007083	Missense_Mutation	novel	P3262L	0.4
SKCM	chr2	21008688	Missense_Mutation	novel	N2727S	0.31
SKCM	chr2	21008945	Silent	NA	I2641I	0.48
SKCM	chr2	21022954	Missense_Mutation	NA	G898E	0.49
SKCM	chr2	21005807	Silent	NA	F3687F	0.26
SKCM	chr2	21016538	Missense_Mutation	NA	R1078K	0.31
SKCM	chr2	21002684	Silent	NA	F4246F	0.32
SKCM	chr2	21001528	3'UTR	novel		0.36
SKCM	chr2	21006176	Silent	NA	E3564E	0.08
SKCM	chr2	21007698	Missense_Mutation	NA	K3057I	0.07
SKCM	chr2	21005178	Missense_Mutation	rs750179992	T3897I	0.37
SKCM	chr2	21002804	Silent	NA	G4206G	0.3
SKCM	chr2	21012308	Silent	NA	L1520L	0.28
SKCM	chr2	21029778	Missense_Mutation	NA	G493E	0.28
SKCM	chr2	21006722	Silent	NA	E3382E	0.4
SKCM	chr2	21002691	Missense_Mutation	NA	S4244F	0.36
SKCM	chr2	21010921	Missense_Mutation	NA	L1983F	0.38
SKCM	chr2	21014469	Missense_Mutation	NA	P1274L	0.39
SKCM	chr2	21005509	Missense_Mutation	NA	P3787A	0.12
SKCM	chr2	21009890	Silent	rs542336755	G2326G	0.07
SKCM	chr2	21014477	Silent	novel	F1271F	0.08
SKCM	chr2	21015250	Silent	novel	K1173K	0.2
SKCM	chr2	21002805	Missense_Mutation	novel	G4206E	0.13
SKCM	chr2	21005686	Missense_Mutation	NA	D3728N	0.18
SKCM	chr2	21007236	Missense_Mutation	rs768051007	N3211S	0.5
SKCM	chr2	21007017	Missense_Mutation	NA	S3284F	0.43
SKCM	chr2	21004316	Missense_Mutation	NA	D4014N	0.25
SKCM	chr2	21008668	Missense_Mutation	NA	P2734S	0.12
SKCM	chr2	21005300	Silent	rs542175556	I3856I	0.09
SKCM	chr2	21011794	Missense_Mutation	novel	E1692K	0.21
SKCM	chr2	21002111	Silent	NA	S4437S	0.32
SKCM	chr2	21005495	Silent	NA	F3791F	0.4
SKCM	chr2	21002662	Missense_Mutation	NA	P4254S	0.36
SKCM	chr2	21008001	Missense_Mutation	NA	S2956F	0.18
SKCM	chr2	21007693	Missense_Mutation	rs146377316	R3059C	0.44
SKCM	chr2	21011123	Silent	NA	G1915G	0.35
SKCM	chr2	21007423	Missense_Mutation	rs759354804	D3149N	0.41
SKCM	chr2	21002691	Missense_Mutation	NA	S4244F	0.29
SKCM	chr2	21003105	Missense_Mutation	NA	R4106K	0.31
SKCM	chr2	21006946	Missense_Mutation	NA	H3308Y	0.04
SKCM	chr2	21009418	Silent	NA	L2484L	0.28
SKCM	chr2	21011647	Missense_Mutation	NA	D1741N	0.06
SKCM	chr2	21015190	Silent	rs267599187	F1193F	0.3
SKCM	chr2	21016459	Silent	rs780454824	V1104V	0.06
SKCM	chr2	21006067	Nonsense_Mutation	novel	Q3601*	0.23
SKCM	chr2	21015129	Missense_Mutation	novel	H1214Y	0.31
SKCM	chr2	21005259	Missense_Mutation	NA	S3870F	0.12
SKCM	chr2	21032363	Missense_Mutation	rs148167725	A448V	0.52
SKCM	chr2	21008635	Missense_Mutation	NA	H2745Y	0.15
SKCM	chr2	21007693	Missense_Mutation	rs146377316	R3059C	0.37
SKCM	chr2	21012489	Missense_Mutation	NA	S1460F	0.29
SKCM	chr2	21007408	Missense_Mutation	NA	E3154K	0.49
SKCM	chr2	21009539	Silent	novel	I2443I	0.23
SKCM	chr2	21002474	Silent	novel	Q4316Q	0.19
SKCM	chr2	21008644	Nonsense_Mutation	novel	Q2742*	0.26
SKCM	chr2	21016551	Missense_Mutation	rs72653074	G1074R	0.25
SKCM	chr2	21008082	Nonsense_Mutation	NA	W2929*	0.72
SKCM	chr2	21007462	Missense_Mutation	rs72653102	R3136C	0.4
SKCM	chr2	21006185	Silent	NA	S3561S	0.42
SKCM	chr2	21025029	Silent	NA	L780L	0.15
SKCM	chr2	21023608	Missense_Mutation	novel	G841R	0.4
SKCM	chr2	21027893	Missense_Mutation	NA	P668S	0.36
SKCM	chr2	21009796	Missense_Mutation	novel	M2358L	0.33
SKCM	chr2	21013214	Missense_Mutation	rs267599185	R1388C	0.41
SKCM	chr2	21002154	Missense_Mutation	novel	S4423F	0.5
SKCM	chr2	21005806	Silent	NA	L3688L	0.34
SKCM	chr2	21007233	Missense_Mutation	rs774659447	R3212K	0.34
SKCM	chr2	21006605	Missense_Mutation	NA	M3421I	0.3
SKCM	chr2	21007019	Silent	rs760902221	F3283F	0.03
SKCM	chr2	21005761	Missense_Mutation	rs777896608	R3703C	0.45
SKCM	chr2	21013174	Missense_Mutation	NA	S1401F	0.41
SKCM	chr2	21012443	Silent	novel	K1475K	0.39
SKCM	chr2	21028498	Missense_Mutation	NA	S553F	0.45
SKCM	chr2	21008143	Missense_Mutation	rs200824333	E2909K	0.21
SKCM	chr2	21002465	Silent	novel	E4319E	0.34
SKCM	chr2	21001682	3'UTR	novel		0.27
SKCM	chr2	21006614	Silent	rs781639766	T3418T	0.31
SKCM	chr2	21002691	Missense_Mutation	NA	S4244F	0.37
SKCM	chr2	21008064	Missense_Mutation	novel	R2935K	0.11
SKCM	chr2	21002892	Missense_Mutation	NA	R4177Q	0.23
SKCM	chr2	21006973	Silent	NA	L3299L	0.26
SKCM	chr2	21009058	Missense_Mutation	NA	L2604F	0.18
SKCM	chr2	21009306	Missense_Mutation	NA	D2521G	0.25
SKCM	chr2	21010315	Missense_Mutation	NA	I2185L	0.27
SKCM	chr2	21011465	Silent	rs149787297	L1801L	0.06
SKCM	chr2	21013388	Silent	NA	L1330L	0.08
SKCM	chr2	21024969	Silent	NA	L800L	0.08
SKCM	chr2	21029690	Missense_Mutation	novel	M522I	0.07
SKCM	chr2	21029778	Missense_Mutation	NA	G493E	0.19
SKCM	chr2	21029981	Silent	NA	L463L	0.06
SKCM	chr2	21037173	Missense_Mutation	NA	R207I	0.12
SKCM	chr2	21042379	Silent	NA	A73A	0.18
SKCM	chr2	21008512	Missense_Mutation	rs373774326	E2786K	0.31
SKCM	chr2	21022831	Missense_Mutation	NA	G939D	0.31
SKCM	chr2	21026951	Missense_Mutation	NA	G694E	0.32
SKCM	chr2	21003044	Silent	NA	I4126I	0.23
SKCM	chr2	21006548	Silent	rs762592684	F3440F	0.43
SKCM	chr2	21007408	Missense_Mutation	NA	E3154K	0.21
SKCM	chr2	21011035	Missense_Mutation	NA	D1945N	0.25
SKCM	chr2	21011208	Missense_Mutation	NA	S1887L	0.24
SKCM	chr2	21026906	Missense_Mutation	NA	G709E	0.24
SKCM	chr2	21016530	Missense_Mutation	NA	D1081N	0.45
SKCM	chr2	21006940	Missense_Mutation	novel	P3310S	0.52
SKCM	chr2	21005503	Missense_Mutation	rs752262589	V3789I	0.28
SKCM	chr2	21006927	Missense_Mutation	novel	K3314R	0.27
SKCM	chr2	21037981	Missense_Mutation	novel	E172K	0.08
SKCM	chr2	21002716	Missense_Mutation	NA	H4236Y	0.27
SKCM	chr2	21010633	Missense_Mutation	NA	E2079K	0.09
SKCM	chr2	21015258	Missense_Mutation	NA	E1171K	0.4
SKCM	chr2	21006434	Silent	NA	D3478D	0.25
SKCM	chr2	21025027	Missense_Mutation	novel	G781E	0.12
SKCM	chr2	21009040	Missense_Mutation	NA	A2610T	0.48
SKCM	chr2	21002130	Missense_Mutation	novel	N4431S	0.21
SKCM	chr2	21004397	Missense_Mutation	novel	H3987Y	0.3
SKCM	chr2	21005678	Silent	NA	F3730F	0.15
SKCM	chr2	21012591	Missense_Mutation	novel	L1426Q	0.17
SKCM	chr2	21002053	Missense_Mutation	rs183812948	D4457N	0.45
SKCM	chr2	21009289	Missense_Mutation	NA	D2527N	0.2
SKCM	chr2	21006396	Missense_Mutation	NA	S3491F	0.44
SKCM	chr2	21009823	Missense_Mutation	NA	E2349K	0.52
SKCM	chr2	21004441	Missense_Mutation	NA	G3972E	0.32
SKCM	chr2	21008645	Silent	rs773868517	F2741F	0.33
SKCM	chr2	21010411	Missense_Mutation	rs767731326	E2153K	0.56
SKCM	chr2	21033504	Missense_Mutation	rs770369582	G307S	0.36
SKCM	chr2	21005969	Nonsense_Mutation	NA	W3633*	0.31
SKCM	chr2	21007891	Missense_Mutation	NA	D2993N	0.29
SKCM	chr2	21007434	Missense_Mutation	NA	P3145L	0.17
SKCM	chr2	21004304	Missense_Mutation	NA	D4018N	0.61
SKCM	chr2	21008668	Missense_Mutation	NA	P2734S	0.59
SKCM	chr2	21010925	Nonsense_Mutation	NA	W1981*	0.62
SKCM	chr2	21005595	Missense_Mutation	NA	V3758A	0.29
SKCM	chr2	21007418	Silent	NA	F3150F	0.3
SKCM	chr2	21009277	Missense_Mutation	rs149358359	E2531K	0.28
SKCM	chr2	21007009	Missense_Mutation	novel	G3287S	0.46
SKCM	chr2	21007150	Missense_Mutation	rs769213768	D3240N	0.33
SKCM	chr2	21012006	Missense_Mutation	NA	S1621F	0.32
SKCM	chr2	21035616	Silent	rs780876397	K262K	0.78
SKCM	chr2	21002159	Silent	NA	F4421F	0.22
SKCM	chr2	21006282	Missense_Mutation	NA	S3529L	0.24
SKCM	chr2	21011717	Missense_Mutation	rs148451559	M1717I	0.3
SKCM	chr2	21012015	Missense_Mutation	novel	S1618L	0.37
SKCM	chr2	21002313	Missense_Mutation	novel	A4370V	0.53
SKCM	chr2	21008254	Missense_Mutation	rs267599182	G2872R	0.61
SKCM	chr2	21010334	Missense_Mutation	NA	M2178I	0.5
SKCM	chr2	21030011	Missense_Mutation	novel	H453Y	0.27
SKCM	chr2	21002386	Missense_Mutation	NA	K4346E	0.32
SKCM	chr2	21011974	Missense_Mutation	NA	G1632S	0.36
SKCM	chr2	21005504	Silent	NA	E3788E	0.35
SKCM	chr2	21008923	Missense_Mutation	NA	E2649K	0.38
SKCM	chr2	21010064	Missense_Mutation	NA	Q2268H	0.05
SKCM	chr2	21012343	Missense_Mutation	NA	P1509S	0.36
SKCM	chr2	21006380	Silent	NA	T3496T	0.9
SKCM	chr2	21001999	Missense_Mutation	NA	E4475K	0.6
SKCM	chr2	21002116	Missense_Mutation	novel	L4436F	0.28
SKCM	chr2	21007058	Silent	rs138010392	F3270F	0.53
SKCM	chr2	21009556	Missense_Mutation	NA	E2438K	0.44
SKCM	chr2	21025046	Missense_Mutation	novel	A775T	0.45
SKCM	chr2	21028372	Missense_Mutation	novel	S595F	0.45
SKCM	chr2	21035706	Splice_Region	NA	T232T	0.56
SKCM	chr2	21022883	Silent	novel	L922L	0.46
SKCM	chr2	21002471	Silent	NA	L4317L	0.47
SKCM	chr2	21006376	Missense_Mutation	NA	G3498R	0.39
SKCM	chr2	21005880	Missense_Mutation	rs267599179	G3663E	0.18
SKCM	chr2	21016576	Silent	NA	Q1065Q	0.16
SKCM	chr2	21002986	Missense_Mutation	rs778195760	D4146N	0.09
SKCM	chr2	21009277	Missense_Mutation	rs149358359	E2531K	0.46
SKCM	chr2	21008828	Silent	novel	L2680L	0.36
SKCM	chr2	21005495	Silent	NA	F3791F	0.1
STAD	chr2	21015203	Frame_Shift_Ins	NA	*M1189Nfs14**	0.22
STAD	chr2	21002251	Missense_Mutation	novel	P4391A	0.23
STAD	chr2	21033512	Missense_Mutation	NA	K304R	0.16
STAD	chr2	21009335	Silent	NA	K2511K	0.4
STAD	chr2	21005214	Missense_Mutation	NA	A3885V	0.2
STAD	chr2	21009963	Missense_Mutation	NA	G2302V	0.05
STAD	chr2	21010967	Missense_Mutation	NA	K1967N	0.15
STAD	chr2	21006880	Missense_Mutation	novel	F3330V	0.07
STAD	chr2	21007578	Missense_Mutation	NA	K3097T	0.07
STAD	chr2	21010041	Missense_Mutation	NA	I2276T	0.21
STAD	chr2	21005888	Silent	novel	D3660D	0.17
STAD	chr2	21008274	Frame_Shift_Del	novel	*N2865Ifs9**	0.17
STAD	chr2	21015203	Frame_Shift_Ins	NA	*M1189Nfs14**	0.24
STAD	chr2	21004435	Missense_Mutation	rs762783264	A3974V	0.1
STAD	chr2	21008003	Silent	novel	T2955T	0.11
STAD	chr2	21024969	Silent	novel	L800L	0.11
STAD	chr2	21009905	Silent	novel	V2321V	0.07
STAD	chr2	21012512	Silent	novel	L1452L	0.29
STAD	chr2	21014482	Missense_Mutation	NA	D1270Y	0.32
STAD	chr2	21007891	Missense_Mutation	NA	D2993N	0.29
STAD	chr2	21011288	Missense_Mutation	rs199585500	Q1860H	0.34
STAD	chr2	21010799	Frame_Shift_Ins	novel	*I2024Nfs2**	0.36
STAD	chr2	21019043	Missense_Mutation	NA	R1024G	0.38
STAD	chr2	21011151	Missense_Mutation	NA	T1906I	0.59
STAD	chr2	21003044	Silent	NA	I4126I	0.33
STAD	chr2	21006223	Missense_Mutation	NA	N3549H	0.37
STAD	chr2	21008923	Missense_Mutation	NA	E2649K	0.32
STAD	chr2	21010698	Missense_Mutation	NA	F2057C	0.34
STAD	chr2	21012570	Missense_Mutation	rs200708197	S1433L	0.35
STAD	chr2	21015453	Missense_Mutation	rs199859104	S1142L	0.28
STAD	chr2	21019905	Splice_Region	NA	G939G	0.29
STAD	chr2	21005461	Missense_Mutation	NA	P3803S	0.27
STAD	chr2	21008115	Missense_Mutation	novel	H2918R	0.47
STAD	chr2	21008757	Missense_Mutation	rs201874707	A2704V	0.39
STAD	chr2	21011413	Missense_Mutation	novel	L1819M	0.12
STAD	chr2	21022926	Silent	rs72653068	H907H	0.38
STAD	chr2	21007461	Missense_Mutation	rs199590149	R3136H	0.09
STAD	chr2	21008825	In_Frame_Ins	novel	N2681delinsKSRYF	0.04
STAD	chr2	21013421	Frame_Shift_Ins	novel	*P1319Cfs41**	0.06
STAD	chr2	21007857	Missense_Mutation	NA	A3004D	0.37
STAD	chr2	21002077	Missense_Mutation	NA	Q4449K	0.3
STAD	chr2	21008433	Missense_Mutation	novel	A2812E	0.06
STAD	chr2	21009143	Silent	NA	K2575K	0.05
STAD	chr2	21029676	Missense_Mutation	NA	A527V	0.22
STAD	chr2	21005616	Missense_Mutation	NA	V3751A	0.33
STAD	chr2	21008421	Missense_Mutation	novel	N2816T	0.18
STAD	chr2	21002804	Silent	NA	G4206G	0.35
STAD	chr2	21007578	Missense_Mutation	NA	K3097T	0.09
STAD	chr2	21003137	Silent	rs749245462	L4095L	0.25
STAD	chr2	21011939	Silent	rs200623857	A1643A	0.11
STAD	chr2	21006299	Silent	NA	S3523S	0.22
STAD	chr2	21042470	Missense_Mutation	NA	A43V	0.28
STAD	chr2	21001751	Silent	novel	G4557G	0.51
STAD	chr2	21002723	Silent	rs56675344	S4233S	0.5
STAD	chr2	21025043	Missense_Mutation	rs536328155	Y776H	0.15
STAD	chr2	21005580	Missense_Mutation	NA	L3763R	0.29
STAD	chr2	21012457	Missense_Mutation	NA	L1471V	0.15
STAD	chr2	21032448	Missense_Mutation	rs192004342	E420K	0.32
STAD	chr2	21029752	Missense_Mutation	rs767615659	L502V	0.14
STAD	chr2	21008144	Silent	rs755498745	N2908N	0.11
STAD	chr2	21015182	Missense_Mutation	NA	D1196A	0.21
STAD	chr2	21011012	Missense_Mutation	NA	H1952Q	0.04
STAD	chr2	21011870	Silent	NA	V1666V	0.05
STAD	chr2	21010655	Silent	NA	L2071L	0.25
STAD	chr2	21019062	Silent	rs558838327	S1017S	0.22
STAD	chr2	21015140	Missense_Mutation	NA	R1210T	0.05
STAD	chr2	21006139	Missense_Mutation	novel	F3577I	0.52
STAD	chr2	21004404	Silent	NA	T3984T	0.22
STAD	chr2	21037195	Missense_Mutation	NA	A200S	0.14
STAD	chr2	21007058	Silent	rs138010392	F3270F	0.08
STAD	chr2	21010340	Silent	NA	T2176T	0.26
STAD	chr2	21012595	Missense_Mutation	NA	S1425P	0.19
STAD	chr2	21011963	Missense_Mutation	NA	K1635N	0.37
STAD	chr2	21032387	Missense_Mutation	NA	A440V	0.25
STAD	chr2	21002970	Missense_Mutation	NA	L4151P	0.26
STAD	chr2	21003186	Missense_Mutation	NA	G4079E	0.24
STAD	chr2	21029954	Nonsense_Mutation	rs767495928	E472*	0.12
STAD	chr2	21026822	Missense_Mutation	novel	H737L	0.15
STAD	chr2	21008614	Missense_Mutation	novel	V2752L	0.22
STAD	chr2	21012076	Silent	rs760171163	L1598L	0.13
STAD	chr2	21005971	Missense_Mutation	NA	W3633R	0.32
STAD	chr2	21019900	Missense_Mutation	novel	T941R	0.25
STAD	chr2	21011337	Missense_Mutation	NA	S1844F	0.15
STAD	chr2	21010104	Missense_Mutation	novel	K2255T	0.1
STAD	chr2	21008698	Missense_Mutation	NA	P2724T	0.35
STAD	chr2	21022964	Missense_Mutation	rs371884333	A895T	0.1
STAD	chr2	21019741	Missense_Mutation	rs41288783	P994L	0.18
STAD	chr2	21030001	Missense_Mutation	NA	N456S	0.3
STAD	chr2	21042384	Missense_Mutation	NA	S72R	0.13
STAD	chr2	21027943	Missense_Mutation	NA	A651D	0.2
STAD	chr2	21009925	Nonsense_Mutation	novel	E2315*	0.2
TGCT	chr2	21008050	Missense_Mutation	NA	G2940R	0.29
TGCT	chr2	21016538	Missense_Mutation	novel	R1078T	0.14
THCA	chr2	21013293	Missense_Mutation	NA	N1361K	0.32
THCA	chr2	21013358	In_Frame_Ins	novel	T1339_F1340insAP	0.05
THCA	chr2	21008553	Missense_Mutation	NA	D2772V	0.06
THCA	chr2	21010159	Nonsense_Mutation	novel	I2236_D2237insPQ*	0.13
THCA	chr2	21007822	Nonsense_Mutation	NA	E3016*	0.29
THYM	chr2	21008754	Missense_Mutation	novel	R2705T	0.52
THYM	chr2	21002368	Missense_Mutation	novel	L4352V	0.11
THYM	chr2	21004650	Silent	novel	D3938D	0.09
THYM	chr2	21001516	3'UTR	novel		0.31
UCEC	chr2	21009391	Missense_Mutation	novel	I2493V	0.08
UCEC	chr2	21010734	Missense_Mutation	rs754379217	A2045V	0.23
UCEC	chr2	21001662	3'UTR	novel		0.26
UCEC	chr2	21002587	Nonsense_Mutation	NA	E4279*	0.31
UCEC	chr2	21006043	Missense_Mutation	NA	S3609T	0.38
UCEC	chr2	21009018	Missense_Mutation	NA	F2617C	0.21
UCEC	chr2	21011452	Missense_Mutation	NA	L1806M	0.36
UCEC	chr2	21011978	Silent	NA	I1630I	0.33
UCEC	chr2	21012072	Missense_Mutation	rs746414462	R1599H	0.36
UCEC	chr2	21012618	Missense_Mutation	rs200321839	T1417M	0.25
UCEC	chr2	21016525	Silent	NA	E1082E	0.3
UCEC	chr2	21019811	Missense_Mutation	NA	P971T	0.34
UCEC	chr2	21028498	Missense_Mutation	NA	S553Y	0.38
UCEC	chr2	21034826	Missense_Mutation	novel	F298L	0.04
UCEC	chr2	21002347	Missense_Mutation	novel	F4359L	0.19
UCEC	chr2	21003149	Silent	novel	E4091E	0.06
UCEC	chr2	21006343	Missense_Mutation	NA	Y3509D	0.31
UCEC	chr2	21007148	Silent	rs111899014	D3240D	0.32
UCEC	chr2	21007562	Missense_Mutation	NA	F3102L	0.34
UCEC	chr2	21008096	Silent	NA	S2924S	0.32
UCEC	chr2	21009357	Missense_Mutation	NA	S2504Y	0.05
UCEC	chr2	21011182	Missense_Mutation	NA	F1896I	0.35
UCEC	chr2	21033329	Missense_Mutation	NA	S365Y	0.29
UCEC	chr2	21005401	Missense_Mutation	novel	S3823A	0.37
UCEC	chr2	21007302	Missense_Mutation	novel	P3189H	0.28
UCEC	chr2	21010902	Missense_Mutation	novel	N1989S	0.3
UCEC	chr2	21011872	Missense_Mutation	novel	V1666M	0.1
UCEC	chr2	21019785	Silent	rs145649470	G979G	0.11
UCEC	chr2	21029903	Missense_Mutation	novel	L489M	0.32
UCEC	chr2	21005764	Missense_Mutation	NA	L3702I	0.48
UCEC	chr2	21009357	Missense_Mutation	NA	S2504Y	0.52
UCEC	chr2	21022876	Missense_Mutation	NA	F924C	0.54
UCEC	chr2	21026842	Silent	NA	V730V	0.48
UCEC	chr2	21037138	Missense_Mutation	rs145661815	R219C	0.27
UCEC	chr2	21037236	Missense_Mutation	NA	C186F	0.27
UCEC	chr2	21003192	Missense_Mutation	rs758921822	A4077V	0.34
UCEC	chr2	21005548	Silent	novel	L3774L	0.28
UCEC	chr2	21007224	Missense_Mutation	novel	A3215V	0.07
UCEC	chr2	21007434	Missense_Mutation	novel	P3145H	0.36
UCEC	chr2	21011957	Silent	rs776739789	N1637N	0.29
UCEC	chr2	21028423	Missense_Mutation	novel	V578A	0.36
UCEC	chr2	21037120	Missense_Mutation	novel	L225F	0.45
UCEC	chr2	21038097	Missense_Mutation	novel	L133P	0.3
UCEC	chr2	21012330	Missense_Mutation	rs780817600	R1513Q	0.16
UCEC	chr2	21008452	Missense_Mutation	NA	F2806V	0.44
UCEC	chr2	21009573	Missense_Mutation	NA	Y2432C	0.39
UCEC	chr2	21028040	Missense_Mutation	NA	L619M	0.47
UCEC	chr2	21012439	Frame_Shift_Ins	novel	*Q1477Dfs46**	0.04
UCEC	chr2	21035706	Splice_Region	NA	T232T	0.37
UCEC	chr2	21002914	Missense_Mutation	novel	N4170D	0.35
UCEC	chr2	21007058	Silent	rs138010392	F3270F	0.33
UCEC	chr2	21011152	Missense_Mutation	novel	T1906A	0.33
UCEC	chr2	21005946	Missense_Mutation	novel	S3641F	0.34
UCEC	chr2	21012272	Silent	novel	Q1532Q	0.13
UCEC	chr2	21001599	3'UTR	novel		0.41
UCEC	chr2	21002547	Missense_Mutation	novel	T4292I	0.2
UCEC	chr2	21005558	Silent	novel	I3770I	0.1
UCEC	chr2	21007365	Nonsense_Mutation	novel	S3168*	0.19
UCEC	chr2	21009122	Silent	novel	E2582E	0.26
UCEC	chr2	21011766	Missense_Mutation	novel	G1701V	0.15
UCEC	chr2	21010733	Silent	rs746559574	A2045A	0.41
UCEC	chr2	21005364	Missense_Mutation	novel	I3835S	0.19
UCEC	chr2	21009713	Silent	rs763218698	K2385K	0.33
UCEC	chr2	21007562	Missense_Mutation	NA	F3102L	0.19
UCEC	chr2	21005448	Frame_Shift_Del	NA	L3807*	0.13
UCEC	chr2	21010692	In_Frame_Ins	novel	V2058_K2059insIMRESKCQRFCFQQEFTIVAFV	0.01
UCEC	chr2	21028453	Missense_Mutation	novel	S568I	0.06
UCEC	chr2	21026891	Missense_Mutation	rs779427901	S714I	0.38
UCEC	chr2	21011190	Frame_Shift_Ins	novel	*S1893Kfs40**	0.07
UCEC	chr2	21011519	In_Frame_Ins	novel	T1783_V1784insFV	0.08
UCEC	chr2	21012569	Silent	rs376103623	S1433S	0.35
UCEC	chr2	21002045	Frame_Shift_Ins	novel	*D4459Efs22**	0.07
UCEC	chr2	21006463	Silent	NA	L3469L	0.21
UCEC	chr2	21007694	In_Frame_Ins	novel	V3058_R3059insLC	0.14
UCEC	chr2	21008134	Frame_Shift_Ins	novel	*T2912Lfs5**	0.11
UCEC	chr2	21016641	Nonsense_Mutation	novel	Q1044*	0.12
UCEC	chr2	21016642	Frame_Shift_Ins	novel	*K1043Nfs10**	0.12
UCEC	chr2	21027959	Missense_Mutation	NA	P646S	0.23
UCEC	chr2	21032408	Missense_Mutation	rs13306190	A433V	0.22
UCEC	chr2	21034857	Missense_Mutation	NA	L288R	0.11
UCEC	chr2	21012438	Missense_Mutation	novel	Q1477P	0.06
UCEC	chr2	21010088	Silent	novel	I2260I	0.38
UCEC	chr2	21003044	Silent	NA	I4126I	0.34
UCEC	chr2	21006500	Silent	NA	S3456S	0.34
UCEC	chr2	21008338	Missense_Mutation	NA	L2844M	0.53
UCEC	chr2	21009309	Missense_Mutation	rs199852015	R2520Q	0.4
UCEC	chr2	21011824	Missense_Mutation	rs140858817	M1682V	0.47
UCEC	chr2	21015372	Missense_Mutation	NA	Y1169C	0.47
UCEC	chr2	21025082	Missense_Mutation	NA	K763E	0.53
UCEC	chr2	21028015	Missense_Mutation	novel	V627G	0.42
UCEC	chr2	21033318	Nonsense_Mutation	novel	Q369*	0.16
UCEC	chr2	21022970	Missense_Mutation	novel	D893Y	0.4
UCEC	chr2	21004437	Frame_Shift_Del	novel	*A3974Rfs33**	0.14
UCEC	chr2	21009045	Missense_Mutation	rs767180578	Q2608R	0.19
UCEC	chr2	21009559	Frame_Shift_Ins	novel	*D2437Sfs13**	0.06
UCEC	chr2	21009507	Missense_Mutation	novel	I2454N	0.03
UCEC	chr2	21001713	3'UTR	novel		0.44
UCEC	chr2	21008855	Missense_Mutation	novel	K2671N	0.18
UCEC	chr2	21013186	Missense_Mutation	novel	V1397A	0.41
UCEC	chr2	21014575	Nonsense_Mutation	novel	Q1239*	0.53
UCEC	chr2	21015175	Silent	rs138243977	S1198S	0.38
UCEC	chr2	21027874	Missense_Mutation	novel	K674R	0.51
UCEC	chr2	21028415	Missense_Mutation	novel	L581I	0.4
UCEC	chr2	21002388	Missense_Mutation	novel	F4345C	0.37
UCEC	chr2	21003231	Missense_Mutation	novel	S4064Y	0.17
UCEC	chr2	21005240	Silent	novel	V3876V	0.08
UCEC	chr2	21006471	Missense_Mutation	novel	S3466Y	0.34
UCEC	chr2	21007019	Missense_Mutation	novel	F3283L	0.24
UCEC	chr2	21007562	Missense_Mutation	NA	F3102L	0.38
UCEC	chr2	21008232	Missense_Mutation	novel	N2879I	0.31
UCEC	chr2	21008916	Missense_Mutation	novel	T2651N	0.4
UCEC	chr2	21011697	Missense_Mutation	novel	K1724T	0.35
UCEC	chr2	21011837	Silent	novel	L1677L	0.36
UCEC	chr2	21014517	Missense_Mutation	novel	L1258R	0.42
UCEC	chr2	21016483	Silent	novel	I1096I	0.31
UCEC	chr2	21027835	Missense_Mutation	novel	L687R	0.35
UCEC	chr2	21027931	Missense_Mutation	novel	I655T	0.43
UCEC	chr2	21007958	Silent	NA	V2970V	0.32
UCEC	chr2	21008330	Frame_Shift_Del	novel	*F2846Lfs28**	0.27
UCEC	chr2	21025040	Missense_Mutation	novel	L777I	0.31
UCEC	chr2	21012039	Missense_Mutation	novel	R1610M	0.39
UCEC	chr2	21032390	Missense_Mutation	rs61742990	R439Q	0.17
UCEC	chr2	21025000	Missense_Mutation	novel	H790R	0.4
UCEC	chr2	21001662	3'UTR	novel		0.33
UCEC	chr2	21005930	Silent	novel	S3646S	0.4
UCEC	chr2	21009701	Silent	novel	Y2389Y	0.33
UCEC	chr2	21034831	Missense_Mutation	rs766376456	R297C	0.37
UCEC	chr2	21015377	Nonsense_Mutation	NA	W1167*	0.24
UCEC	chr2	21033315	Silent	NA	L370L	0.31
UCEC	chr2	21025036	Missense_Mutation	rs201595604	R778H	0.27
UCEC	chr2	21008971	Missense_Mutation	NA	F2633L	0.38
UCEC	chr2	21010998	Missense_Mutation	NA	R1957M	0.36
UCEC	chr2	21011991	Nonsense_Mutation	novel	L1626*	0.55
UCEC	chr2	21029942	Missense_Mutation	novel	D476N	0.95
UCEC	chr2	21005558	Silent	novel	I3770I	0.37
UCEC	chr2	21008027	Missense_Mutation	novel	S2947R	0.09
UCEC	chr2	21027920	Missense_Mutation	novel	L659I	0.42
UCEC	chr2	21007564	Missense_Mutation	novel	F3102V	0.36
UCEC	chr2	21012570	Missense_Mutation	rs200708197	S1433L	0.29
UCEC	chr2	21007235	Frame_Shift_Ins	NA	*N3211Kfs14**	0.26
UCEC	chr2	21011167	Missense_Mutation	novel	A1901T	0.29
UCEC	chr2	21011266	Missense_Mutation	novel	L1868I	0.52
UCEC	chr2	21012331	Missense_Mutation	rs139621265	R1513W	0.38
UCEC	chr2	21030013	Missense_Mutation	novel	Y452C	0.4
UCEC	chr2	21037248	Missense_Mutation	novel	V182A	0.43
UCEC	chr2	21042465	Nonsense_Mutation	NA	R45*	0.46
UCEC	chr2	21012352	Nonsense_Mutation	novel	Q1506*	0.13
UCEC	chr2	21005956	Missense_Mutation	rs61744151	R3638W	0.47
UCEC	chr2	21006140	Silent	NA	L3576L	0.41
UCEC	chr2	21006842	Silent	novel	S3342S	0.58
UCEC	chr2	21028426	Missense_Mutation	novel	I577S	0.49
UCEC	chr2	21037142	Silent	novel	P217P	0.46
UCEC	chr2	21002063	Missense_Mutation	novel	S4453R	0.42
UCEC	chr2	21005839	Missense_Mutation	novel	L3677I	0.27
UCEC	chr2	21027893	Missense_Mutation	NA	P668S	0.32
UCEC	chr2	21011415	Nonsense_Mutation	novel	*P1818Lfs6**	0.04
UCEC	chr2	21002023	Missense_Mutation	NA	A4467S	0.1
UCEC	chr2	21003274	Missense_Mutation	novel	E4050Q	0.08
UCEC	chr2	21003275	Frame_Shift_Ins	novel	*D4049Efs6**	0.08
UCEC	chr2	21005644	Missense_Mutation	NA	S3742A	0.32
UCEC	chr2	21007562	Missense_Mutation	NA	F3102L	0.35
UCEC	chr2	21010331	Missense_Mutation	NA	I2179M	0.45
UCEC	chr2	21012439	Frame_Shift_Ins	novel	*Q1477Vfs15**	0.1
UCEC	chr2	21007557	Missense_Mutation	novel	A3104V	0.24
UCEC	chr2	21012546	Frame_Shift_Ins	novel	*E1441Gfs19**	0.3
UCEC	chr2	21016453	Silent	NA	L1106L	0.36
UCEC	chr2	21003044	Silent	NA	I4126I	0.35
UCEC	chr2	21005638	Missense_Mutation	NA	L3744I	0.28
UCEC	chr2	21005946	Missense_Mutation	novel	S3641Y	0.42
UCEC	chr2	21006144	Missense_Mutation	novel	G3575D	0.45
UCEC	chr2	21006300	Missense_Mutation	novel	S3523F	0.47
UCEC	chr2	21007544	Missense_Mutation	novel	E3108D	0.5
UCEC	chr2	21008367	Missense_Mutation	novel	Y2834C	0.45
UCEC	chr2	21008919	Missense_Mutation	novel	F2650C	0.33
UCEC	chr2	21009332	Missense_Mutation	novel	F2512L	0.35
UCEC	chr2	21015371	Nonsense_Mutation	novel	Y1169*	0.43
UCEC	chr2	21040965	Missense_Mutation	novel	S119Y	0.29
UCEC	chr2	21003310	Missense_Mutation	novel	I4038V	0.2
UCEC	chr2	21005609	Missense_Mutation	novel	F3753L	0.07
UCEC	chr2	21007161	Missense_Mutation	novel	E3236G	0.39
UCEC	chr2	21008549	Silent	novel	A2773A	0.47
UCEC	chr2	21015204	Frame_Shift_Del	NA	M1189*	0.24
UCEC	chr2	21002762	Missense_Mutation	novel	F4220L	0.12
UCEC	chr2	21014574	Missense_Mutation	NA	Q1239R	0.3
UCEC	chr2	21002004	Missense_Mutation	novel	A4473D	0.12
UCEC	chr2	21006075	Missense_Mutation	novel	A3598D	0.2
UCEC	chr2	21007857	Missense_Mutation	NA	A3004D	0.14
UCEC	chr2	21010234	Missense_Mutation	novel	L2212I	0.24
UCEC	chr2	21011705	Silent	rs536182427	V1721V	0.09
UCEC	chr2	21033502	Silent	novel	G307G	0.44
UCEC	chr2	21006945	Missense_Mutation	novel	H3308R	0.42
UCEC	chr2	21014473	Missense_Mutation	novel	I1273V	0.45
UCEC	chr2	21002447	Silent	novel	L4325L	0.3
UCEC	chr2	21037124	Silent	novel	S223S	0.38
UCEC	chr2	21002388	Missense_Mutation	novel	F4345C	0.3
UCEC	chr2	21002517	Missense_Mutation	novel	L4302P	0.34
UCEC	chr2	21008419	Missense_Mutation	novel	P2817S	0.39
UCEC	chr2	21014459	Silent	novel	L1277L	0.27
UCEC	chr2	21019100	Missense_Mutation	novel	L1005M	0.31
UCEC	chr2	21033329	Missense_Mutation	NA	S365Y	0.46
UCEC	chr2	21042470	Missense_Mutation	NA	A43V	0.31
UCEC	chr2	21012166	Missense_Mutation	NA	L1568M	0.32
UCEC	chr2	21001904	Silent	novel	L4506L	0.36
UCEC	chr2	21002532	Missense_Mutation	rs375701380	R4297H	0.34
UCEC	chr2	21006079	Missense_Mutation	novel	S3597T	0.37
UCEC	chr2	21007086	Missense_Mutation	novel	S3261Y	0.44
UCEC	chr2	21007761	Missense_Mutation	NA	S3036Y	0.18
UCEC	chr2	21008596	Silent	novel	L2758L	0.44
UCEC	chr2	21009258	Missense_Mutation	NA	S2537Y	0.4
UCEC	chr2	21015451	Missense_Mutation	rs72653077	P1143S	0.33
UCEC	chr2	21033501	Missense_Mutation	novel	L308I	0.35
UCEC	chr2	21037168	Missense_Mutation	novel	L209M	0.34
UCEC	chr2	21019062	Silent	rs558838327	S1017S	0.17
UCEC	chr2	21001946	Silent	rs771143412	H4492H	0.15
UCEC	chr2	21002368	Missense_Mutation	novel	L4352I	0.14
UCEC	chr2	21004596	Silent	NA	A3956A	0.05
UCEC	chr2	21002004	Missense_Mutation	novel	A4473D	0.33
UCEC	chr2	21003187	Missense_Mutation	novel	G4079W	0.43
UCEC	chr2	21009271	Missense_Mutation	novel	Q2533K	0.46
UCEC	chr2	21010085	Missense_Mutation	novel	Q2261H	0.46
UCEC	chr2	21010427	Missense_Mutation	novel	K2147N	0.58
UCEC	chr2	21013349	Missense_Mutation	novel	P1343T	0.35
UCEC	chr2	21026887	Silent	novel	V715V	0.55
UCEC	chr2	21005974	Missense_Mutation	NA	R3632G	0.37
UCEC	chr2	21010340	Silent	NA	T2176T	0.36
UCEC	chr2	21011147	Silent	rs755014418	I1907I	0.45
UCEC	chr2	21019873	Missense_Mutation	rs187506285	T950M	0.33
UCEC	chr2	21011704	Missense_Mutation	rs757793421	D1722N	0.5
UCEC	chr2	21001884	Missense_Mutation	NA	F4513C	0.35
UCEC	chr2	21002724	Missense_Mutation	rs377125320	S4233L	0.2
UCEC	chr2	21006093	Missense_Mutation	NA	S3592F	0.27
UCEC	chr2	21006845	Missense_Mutation	NA	F3341L	0.33
UCEC	chr2	21007116	Missense_Mutation	NA	Y3251C	0.28
UCEC	chr2	21008358	Missense_Mutation	rs776427191	T2837M	0.14
UCEC	chr2	21009977	Silent	novel	L2297L	0.07
UCEC	chr2	21011162	Silent	rs145277222	P1902P	0.3
UCEC	chr2	21011705	Silent	rs536182427	V1721V	0.22
UCEC	chr2	21012570	Missense_Mutation	rs200708197	S1433L	0.32
UCEC	chr2	21010353	Missense_Mutation	novel	S2172Y	0.15
UCEC	chr2	21010650	Missense_Mutation	novel	F2073C	0.13
UCEC	chr2	21022931	Missense_Mutation	novel	F906V	0.19
UCEC	chr2	21038028	Missense_Mutation	novel	I156S	0.08
UCEC	chr2	21015382	Missense_Mutation	novel	A1166T	0.3
UCEC	chr2	21008272	Missense_Mutation	NA	T2866A	0.25
UCEC	chr2	21010326	Missense_Mutation	novel	F2181C	0.06
UCEC	chr2	21032375	Missense_Mutation	rs769425660	A444V	0.38
UCEC	chr2	21011190	Frame_Shift_Ins	novel	*S1893Kfs40**	0.22
UCEC	chr2	21029755	Nonsense_Mutation	novel	Q501*	0.13
UCEC	chr2	21009116	Silent	novel	G2584G	0.44
UCEC	chr2	21033334	Silent	novel	V363V	0.43
UCEC	chr2	21002004	Missense_Mutation	novel	A4473V	0.07
UCEC	chr2	21012300	Nonsense_Mutation	novel	*N1523Ifs12**	0.05
UCEC	chr2	21010107	Missense_Mutation	novel	T2254N	0.06
UCEC	chr2	21032363	Missense_Mutation	rs148167725	A448V	0.39
UCEC	chr2	21009268	Nonsense_Mutation	rs145143533	R2534*	0.11
UCEC	chr2	21026836	Missense_Mutation	novel	K732N	0.2
UCEC	chr2	21008305	In_Frame_Ins	novel	S2854_N2855insLRLRVGIMNSGIAIEGKS	0.04
UCEC	chr2	21026901	Missense_Mutation	rs746180039	F711L	0.11
UCEC	chr2	21001664	3'UTR	novel		0.17
UCEC	chr2	21010868	Silent	rs774954310	N2000N	0.37
UCEC	chr2	21015203	Frame_Shift_Ins	NA	*M1189Nfs14**	0.21
UCEC	chr2	21029985	Missense_Mutation	novel	Q461H	0.31
UCEC	chr2	21003204	Missense_Mutation	novel	N4073S	0.31
UCEC	chr2	21007708	Missense_Mutation	novel	G3054W	0.2
UCEC	chr2	21008084	Silent	novel	S2928S	0.12
UCEC	chr2	21009559	Frame_Shift_Ins	novel	*D2437Sfs13**	0.13
UCEC	chr2	21015218	Frame_Shift_Ins	novel	*V1184Dfs7**	0.06
UCEC	chr2	21011286	Missense_Mutation	NA	G1861V	0.15
UCEC	chr2	21002067	Missense_Mutation	NA	L4452H	0.11
UCEC	chr2	21005210	Silent	rs757728731	R3886R	0.12
UCEC	chr2	21006302	Missense_Mutation	novel	N3522K	0.13
UCEC	chr2	21007561	Missense_Mutation	NA	S3103A	0.47
UCEC	chr2	21008659	Missense_Mutation	NA	H2737N	0.15
UCEC	chr2	21009018	Missense_Mutation	NA	F2617C	0.28
UCEC	chr2	21012095	Missense_Mutation	novel	F1591L	0.09
UCEC	chr2	21013402	Missense_Mutation	NA	S1325Y	0.44
UCEC	chr2	21007761	Missense_Mutation	NA	S3036Y	0.37
UCEC	chr2	21013533	Splice_Region	rs72653079	S1281S	0.28
UCEC	chr2	21007562	Missense_Mutation	NA	F3102L	0.25
UCEC	chr2	21010527	Missense_Mutation	novel	A2114V	0.57
UCEC	chr2	21002596	Missense_Mutation	NA	L4276V	0.29
UCEC	chr2	21004270	Missense_Mutation	novel	Q4029L	0.08
UCEC	chr2	21008971	Missense_Mutation	NA	F2633V	0.3
UCEC	chr2	21012412	Frame_Shift_Ins	novel	*I1486Ffs40**	0.05
UCEC	chr2	21012413	Frame_Shift_Ins	novel	*I1486Dfs2**	0.02
UCEC	chr2	21013440	Frame_Shift_Del	novel	R1308*	0.07
UCEC	chr2	21014459	Silent	NA	L1277L	0.27
UCEC	chr2	21027964	Missense_Mutation	rs147173587	S644Y	0.12
UCEC	chr2	21011357	Silent	novel	K1837K	0.34
UCEC	chr2	21005261	Missense_Mutation	NA	F3869L	0.37
UCEC	chr2	21011146	Missense_Mutation	rs751368655	D1908N	0.3
UCEC	chr2	21012126	Missense_Mutation	novel	F1581S	0.06
UCEC	chr2	21002740	Missense_Mutation	novel	L4228M	0.29
UCEC	chr2	21005747	Silent	novel	A3707A	0.39
UCEC	chr2	21006592	Missense_Mutation	rs753767897	A3426T	0.16
UCEC	chr2	21008669	Silent	novel	V2733V	0.52
UCEC	chr2	21011872	Missense_Mutation	novel	V1666M	0.33
UCEC	chr2	21015151	Missense_Mutation	novel	M1206I	0.35
UCEC	chr2	21016552	Silent	rs750588820	L1073L	0.46
UCEC	chr2	21019734	Silent	rs137875230	T996T	0.27
UCEC	chr2	21026821	Silent	rs746446519	H737H	0.14
UCEC	chr2	21027970	Missense_Mutation	novel	S642F	0.15
UCEC	chr2	21037219	Missense_Mutation	rs200662943	V192I	0.41
UCEC	chr2	21005761	Missense_Mutation	novel	R3703S	0.5
UCEC	chr2	21006476	Silent	rs754870552	F3464F	0.18
UCEC	chr2	21032363	Missense_Mutation	rs148167725	A448V	0.59
UCEC	chr2	21009237	Missense_Mutation	novel	S2544I	0.33
UCEC	chr2	21007235	Frame_Shift_Ins	NA	*N3211Kfs14**	0.28
UCEC	chr2	21038106	Missense_Mutation	rs759513027	E130G	0.41
UCEC	chr2	21008425	Missense_Mutation	NA	S2815T	0.17
UCEC	chr2	21009258	Missense_Mutation	NA	S2537Y	0.27
UCEC	chr2	21010573	Missense_Mutation	NA	L2099M	0.22
UCEC	chr2	21014565	Missense_Mutation	NA	S1242Y	0.11
UCEC	chr2	21027860	Missense_Mutation	NA	A679T	0.28
UCEC	chr2	21008791	Frame_Shift_Ins	novel	*L2693Ifs5**	0.07
UCEC	chr2	21007038	Missense_Mutation	novel	A3277V	0.39
UCEC	chr2	21002536	Silent	novel	L4296L	0.37
UCEC	chr2	21012570	Missense_Mutation	rs200708197	S1433L	0.35
UCEC	chr2	21016566	Missense_Mutation	novel	F1069V	0.46
UCEC	chr2	21026842	Silent	novel	V730V	0.39
UCEC	chr2	21005361	Missense_Mutation	novel	A3836V	0.31
UCEC	chr2	21007458	Missense_Mutation	novel	L3137R	0.44
UCEC	chr2	21009372	Missense_Mutation	novel	A2499V	0.43
UCEC	chr2	21010309	Missense_Mutation	novel	D2187N	0.42
UCEC	chr2	21037181	Silent	novel	S204S	0.27
UCEC	chr2	21041001	Missense_Mutation	novel	P107H	0.37
UCS	chr2	21023012	Missense_Mutation	rs564030306	V879M	0.36
UCS	chr2	21033457	Silent	rs755978246	A322A	0.43
UCS	chr2	21002724	Missense_Mutation	rs377125320	S4233L	0.28
UCS	chr2	21007761	Missense_Mutation	NA	S3036Y	0.29
UCS	chr2	21006278	Silent	novel	V3530V	0.51

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
CESC	AMP	0.2305	0.099937
KIRP	DEL	0.0243	0.08832
LUSC	DEL	0.0379	0.20634
OV	DEL	0.1382	0.087942
PAAD	DEL	0.0978	0.2014
TGCT	AMP	0.28	0.0050216
UCEC	DEL	0.026	0.18809

Survival Analysis

Cancer	P-value	Q-value
STAD	0.039	Kaplan-Meier Survival Analysis
SARC	0.023	Kaplan-Meier Survival Analysis
UCS	0.05	Kaplan-Meier Survival Analysis
HNSC	0.012	Kaplan-Meier Survival Analysis
PRAD	0.045	Kaplan-Meier Survival Analysis
KIRP	0.0088	Kaplan-Meier Survival Analysis
GBM	0.013	Kaplan-Meier Survival Analysis
LIHC	0.011	Kaplan-Meier Survival Analysis
LGG	0.00014	Kaplan-Meier Survival Analysis
LUAD	0.022	Kaplan-Meier Survival Analysis
OV	0.032	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742