EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000084733 (Gene tree)
Gene ID: 10890
Gene Symbol: RAB10
Alias: -
Full Name: RAB10, member RAS oncogene family
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 103,595 bases
Position: chr2:26,033,860-26,137,454
Accession: 9759
RBP type: non-canonical RBP
Summary: RAB10 belongs to the RAS (see HRAS; MIM 190020) superfamily of small GTPases. RAB proteins localize to exocytic and endocytic compartments and regulate intracellular vesicle trafficking (Bao et al., 1998 [PubMed 9918381]).[supplied by OMIM, Mar 2009]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000264710	RAB10-201	3535	XM_024452565	ENSP00000264710	200 (aa)	XP_024308333	P61026
ENST00000462003	RAB10-202	584	-	-	- (aa)	-	-
ENST00000473035	RAB10-203	571	-	-	- (aa)	-	-
ENST00000495146	RAB10-204	1292	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000084733's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04144	Endocytosis	KEGG
hsa04152	AMPK signaling pathway	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000084733	Vaccine Potency	8E-6	22542470

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000084733	rs28699126	2	26134425	T	Mean corpuscular hemoglobin	27863252	[0.022-0.039] unit decrease	0.03093029	EFO_0004527
ENSG00000084733	rs2243834	2	26134879	T	Mean corpuscular volume	27863252	[0.017-0.034] unit decrease	0.02553421	EFO_0004526
ENSG00000084733	rs13388915	2	26049733	?	Immune response to smallpox vaccine (IL-6)	22542470			EFO_0004645
ENSG00000084733	rs2384322	2	26068277	?	Mean corpuscular hemoglobin	30595370			EFO_0004527

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000084733's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000139	Golgi membrane	-	IEA	Component
GO:0000145	exocyst	-	ISS	Component
GO:0003924	GTPase activity	21873635.	IBA	Function
GO:0005515	protein binding	25416956.26824392.30021884.	IPI	Function
GO:0005525	GTP binding	20937701.	IDA	Function
GO:0005768	endosome	21873635.	IBA	Component
GO:0005768	endosome	20576682.	IDA	Component
GO:0005789	endoplasmic reticulum membrane	23263280.	IDA	Component
GO:0005794	Golgi apparatus	21873635.	IBA	Component
GO:0005794	Golgi apparatus	23263280.	IDA	Component
GO:0005802	trans-Golgi network	-	ISS	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005886	plasma membrane	21873635.	IBA	Component
GO:0005886	plasma membrane	22908308.	IDA	Component
GO:0005886	plasma membrane	-	TAS	Component
GO:0005913	cell-cell adherens junction	25468996.	HDA	Component
GO:0005925	focal adhesion	21423176.	HDA	Component
GO:0005929	cilium	20576682.	IDA	Component
GO:0006886	intracellular protein transport	21873635.	IBA	Process
GO:0006893	Golgi to plasma membrane transport	-	ISS	Process
GO:0006904	vesicle docking involved in exocytosis	21873635.	IBA	Process
GO:0007409	axonogenesis	-	ISS	Process
GO:0008021	synaptic vesicle	21873635.	IBA	Component
GO:0009306	protein secretion	21873635.	IBA	Process
GO:0016192	vesicle-mediated transport	-	ISS	Process
GO:0016197	endosomal transport	16641372.	IMP	Process
GO:0017157	regulation of exocytosis	21873635.	IBA	Process
GO:0019003	GDP binding	20937701.	IDA	Function
GO:0019882	antigen processing and presentation	19717423.	IMP	Process
GO:0030659	cytoplasmic vesicle membrane	-	TAS	Component
GO:0030667	secretory granule membrane	-	TAS	Component
GO:0030670	phagocytic vesicle membrane	-	IEA	Component
GO:0030859	polarized epithelial cell differentiation	-	ISS	Process
GO:0031489	myosin V binding	22908308.	IPI	Function
GO:0032482	Rab protein signal transduction	21873635.	IBA	Process
GO:0032593	insulin-responsive compartment	21873635.	IBA	Component
GO:0032593	insulin-responsive compartment	22908308.	IDA	Component
GO:0032869	cellular response to insulin stimulus	21873635.	IBA	Process
GO:0032869	cellular response to insulin stimulus	-	ISS	Process
GO:0043001	Golgi to plasma membrane protein transport	-	ISS	Process
GO:0043312	neutrophil degranulation	-	TAS	Process
GO:0045200	establishment of neuroblast polarity	-	ISS	Process
GO:0048471	perinuclear region of cytoplasm	-	ISS	Component
GO:0055037	recycling endosome	21873635.	IBA	Component
GO:0055037	recycling endosome	16641372.	IDA	Component
GO:0055038	recycling endosome membrane	-	IEA	Component
GO:0070062	extracellular exosome	19056867.20458337.23533145.	HDA	Component
GO:0070382	exocytic vesicle	18504258.	IDA	Component
GO:0071782	endoplasmic reticulum tubular network	23263280.	IDA	Component
GO:0071786	endoplasmic reticulum tubular network organization	23263280.24891604.	IMP	Process
GO:0072659	protein localization to plasma membrane	21873635.	IBA	Process
GO:0072659	protein localization to plasma membrane	-	ISS	Process
GO:0090150	establishment of protein localization to membrane	24006491.	IMP	Process
GO:0097051	establishment of protein localization to endoplasmic reticulum membrane	23263280.	IMP	Process
GO:0098609	cell-cell adhesion	-	IEA	Process
GO:0098641	cadherin binding involved in cell-cell adhesion	25468996.	HDA	Function
GO:1903361	protein localization to basolateral plasma membrane	-	ISS	Process