EuRBPDB

Basic Information
Cancer Related Information

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000085224 (Gene tree)
Gene ID: 546
Gene Symbol: ATRX
Alias: XH2|XNP|RAD54|JMS|MRX52
Full Name: ATRX chromatin remodeler
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 281,392 bases
Position: chrX:77,504,878-77,786,269
Accession: 886
RBP type: non-canonical RBP
Summary: The protein encoded by this gene contains an ATPase/helicase domain, and thus it belongs to the SWI/SNF family of chromatin remodeling proteins. This protein is found to undergo cell cycle-dependent phosphorylation, which regulates its nuclear matrix and chromatin association, and suggests its involvement in the gene regulation at interphase and chromosomal segregation in mitosis. Mutations in this gene are associated with X-linked syndromes exhibiting cognitive disabilities as well as alpha-thalassemia (ATRX) syndrome. These mutations have been shown to cause diverse changes in the pattern of DNA methylation, which may provide a link between chromatin remodeling, DNA methylation, and gene expression in developmental processes. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2017]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
26577303	Postovulatory aging affects dynamics of mRNA, expression and localization of maternal effect proteins, spindle integrity and pericentromeric proteins in mouse oocytes.	Hum Reprod	2016 Jan	Trapphoff T	doi: 10.1093/humrep/dev279
23331137	A deleterious effect associated with UNH159 is attenuated in twin embryos of an inbred line of blue tilapia Oreochromis aureus.	J Fish Biol	2013 Jan	Shirak A	doi: 10.1111/j.1095-8649.2012.03474.x
27462434	Structural basis for Sfm1 functioning as a protein arginine methyltransferase.	Cell Discov	2015 Dec 29	Lv F	doi: 10.1038/celldisc.2015.37

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000623321	ATRX-211	1860	-	ENSP00000485127	528 (aa)	-	A0A096LNN3
ENST00000460639	ATRX-204	461	-	-	- (aa)	-	-
ENST00000623706	ATRX-212	7245	-	-	- (aa)	-	-
ENST00000493470	ATRX-207	2967	-	ENSP00000485408	293 (aa)	-	A0A096LP59
ENST00000625063	ATRX-219	593	-	ENSP00000485099	198 (aa)	-	A0A096LNL6
ENST00000637175	ATRX-223	100	-	-	- (aa)	-	-
ENST00000400866	ATRX-203	814	-	ENSP00000383663	198 (aa)	-	H0Y3T0
ENST00000623242	ATRX-209	725	-	ENSP00000485183	66 (aa)	-	A0A096LNR8
ENST00000636152	ATRX-221	100	-	-	- (aa)	-	-
ENST00000624166	ATRX-214	4272	-	ENSP00000485103	1351 (aa)	-	A0A096LNL9
ENST00000623316	ATRX-210	803	-	ENSP00000485274	175 (aa)	-	A0A096LNX6
ENST00000395603	ATRX-202	10218	XM_005262157	ENSP00000378967	2454 (aa)	XP_005262214	P46100
ENST00000624668	ATRX-217	583	-	ENSP00000485100	108 (aa)	-	A0A096LNL7
ENST00000624766	ATRX-218	580	-	-	- (aa)	-	-
ENST00000479487	ATRX-205	408	-	-	- (aa)	-	-
ENST00000622960	ATRX-208	628	-	ENSP00000485587	47 (aa)	-	A0A096LPG6
ENST00000624032	ATRX-213	3071	-	ENSP00000485253	954 (aa)	-	A0A096LNW1
ENST00000480283	ATRX-206	10455	-	ENSP00000480196	164 (aa)	-	A0A087WWG0
ENST00000624403	ATRX-216	583	-	-	- (aa)	-	-
ENST00000636868	ATRX-222	100	-	-	- (aa)	-	-
ENST00000373344	ATRX-201	11167	XM_005262153	ENSP00000362441	2492 (aa)	XP_005262210	P46100
ENST00000637959	ATRX-224	86	-	-	- (aa)	-	-
ENST00000635865	ATRX-220	100	-	ENSP00000490150	6 (aa)	-	UPI0007E52B90
ENST00000624193	ATRX-215	463	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000085224's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000085224's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000085224	ATRX	99	93.909	ENSMUSG00000031229	Atrx	100	93.333	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000212	meiotic spindle organization	-	IEA	Process
GO:0000780	condensed nuclear chromosome, centromeric region	-	IEA	Component
GO:0000784	nuclear chromosome, telomeric region	-	ISS	Component
GO:0000784	nuclear chromosome, telomeric region	-	ISS	Component
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003682	chromatin binding	27029610.	IDA	Function
GO:0004386	helicase activity	-	IEA	Function
GO:0005515	protein binding	10699177.12953102.17296936.22102817.22391447.24651726.25417162.26373281.26496610.27029610.	IPI	Function
GO:0005524	ATP binding	-	IEA	Function
GO:0005634	nucleus	7874112.	TAS	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005720	nuclear heterochromatin	10570185.	TAS	Component
GO:0005721	pericentric heterochromatin	-	ISS	Component
GO:0006281	DNA repair	-	IEA	Process
GO:0006306	DNA methylation	10742099.	TAS	Process
GO:0006334	nucleosome assembly	20651253.	IDA	Process
GO:0006336	DNA replication-independent nucleosome assembly	22391447.	IMP	Process
GO:0006338	chromatin remodeling	20651253.	IDA	Process
GO:0006355	regulation of transcription, DNA-templated	7697714.	TAS	Process
GO:0007283	spermatogenesis	-	IEA	Process
GO:0010571	positive regulation of nuclear cell cycle DNA replication	-	ISS	Process
GO:0015616	DNA translocase activity	12953102.	IDA	Function
GO:0016604	nuclear body	-	IDA	Component
GO:0016605	PML body	-	ISS	Component
GO:0030330	DNA damage response, signal transduction by p53 class mediator	-	ISS	Process
GO:0030900	forebrain development	-	IEA	Process
GO:0031297	replication fork processing	-	ISS	Process
GO:0031618	nuclear pericentric heterochromatin	-	IEA	Component
GO:0031933	telomeric heterochromatin	-	ISS	Component
GO:0032206	positive regulation of telomere maintenance	-	ISS	Process
GO:0035064	methylated histone binding	21421568.	IDA	Function
GO:0035128	post-embryonic forelimb morphogenesis	-	IEA	Process
GO:0035264	multicellular organism growth	-	IEA	Process
GO:0042393	histone binding	20211137.22391447.	IDA	Function
GO:0045944	positive regulation of transcription by RNA polymerase II	22391447.	IMP	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0060009	Sertoli cell development	-	IEA	Process
GO:0070087	chromo shadow domain binding	15882967.	IPI	Function
GO:0070192	chromosome organization involved in meiotic cell cycle	-	IEA	Process
GO:0070198	protein localization to chromosome, telomeric region	-	ISS	Process
GO:0072520	seminiferous tubule development	-	IEA	Process
GO:0072711	cellular response to hydroxyurea	-	ISS	Process
GO:1900112	regulation of histone H3-K9 trimethylation	27029610.	IMP	Process
GO:1901581	negative regulation of telomeric RNA transcription from RNA pol II promoter	-	ISS	Process
GO:1901582	positive regulation of telomeric RNA transcription from RNA pol II promoter	26055325.	IMP	Process
GO:1904908	negative regulation of maintenance of mitotic sister chromatid cohesion, telomeric	26373281.	IMP	Process
GO:1990707	nuclear subtelomeric heterochromatin	26055325.	IDA	Component

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
23391111	The genetics of neuroendocrine tumors.	Semin Oncol	2013 Feb	berg K	doi: 10.1053/j.seminoncol.2012.11.005.
27796734	Diagnostic revision of 206 adult gliomas (including 40 oligoastrocytomas) based on ATRX, IDH1/2 and 1p/19q status.	J Neurooncol	2017 Jan	Mellai M	doi: 10.1007/s11060-016-2296-5
28591701	DAXX/ATRX and MEN1 genes are strong prognostic markers in pancreatic neuroendocrine tumors.	Oncotarget	2017 Jul 25	Park JK	doi: 10.18632/oncotarget.17964.
23954140	Clinicopathologic significance of immunostaining of α-thalassemia/mental retardation syndrome X-linked protein and death domain-associated protein in neuroendocrine tumors.	Hum Pathol	2013 Oct	Chen SF	doi: 10.1016/j.humpath.2013.04.025
27869828	Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias.	Nat Genet	2017 Jan	Dunford A	doi: 10.1038/ng.3726
28062559	ATRX and DAXX: Mechanisms and Mutations.	Cold Spring Harb Perspect Med	2017 Mar 1	Dyer MA	doi: 10.1101/cshperspect.a026567.
27578458	Switch telomerase to ALT mechanism by inducing telomeric DNA damages and dysfunction of ATRX and DAXX.	Sci Rep	2016 Aug 31	Hu Y	doi: 10.1038/srep32280.
30226859	ATRX loss induces multiple hallmarks of the alternative lengthening of telomeres (ALT) phenotype in human glioma cell lines in a cell line-specific manner.	PLoS One	2018 Sep 18	Brosnan-Cashman JA	doi: 10.1371/journal.pone.0204159

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq
ACC	chrX	77683857	Nonsense_Mutation	novel	K467*	0.3
ACC	chrX	77620405	Missense_Mutation	NA	N1754K	0.37
ACC	chrX	77663409	Nonsense_Mutation	novel	E1365*	0.21
ACC	chrX	77683830	Nonsense_Mutation	novel	Q476*	0.29
BLCA	chrX	77683536	Missense_Mutation	novel	I574V	0.06
BLCA	chrX	77682699	Nonsense_Mutation	novel	E853*	0.05
BLCA	chrX	77684299	Missense_Mutation	NA	K319N	0.11
BLCA	chrX	77683059	Missense_Mutation	novel	E733K	0.91
BLCA	chrX	77557626	Missense_Mutation	novel	I2175T	0.26
BLCA	chrX	77682970	Missense_Mutation	novel	K762N	0.04
BLCA	chrX	77599443	Missense_Mutation	novel	N1975T	0.08
BLCA	chrX	77676254	Missense_Mutation	novel	D1261N	0.21
BLCA	chrX	77684114	Missense_Mutation	novel	S381L	0.32
BLCA	chrX	77681522	Missense_Mutation	novel	S1245L	0.24
BLCA	chrX	77633270	Missense_Mutation	NA	Q1691E	0.57
BLCA	chrX	77620501	Silent	novel	H1722H	0.9
BLCA	chrX	77681687	Missense_Mutation	novel	R1190K	0.89
BLCA	chrX	77574250	Missense_Mutation	novel	R2109T	0.92
BLCA	chrX	77684051	Missense_Mutation	novel	I402T	0.83
BLCA	chrX	77521426	Missense_Mutation	NA	L2350V	0.15
BLCA	chrX	77684040	Missense_Mutation	NA	H406D	0.47
BLCA	chrX	77681631	Nonsense_Mutation	novel	E1209*	0.21
BLCA	chrX	77681713	Silent	NA	V1181V	0.37
BLCA	chrX	77523303	Missense_Mutation	novel	L2266F	0.68
BLCA	chrX	77682074	Missense_Mutation	NA	S1061C	0.12
BLCA	chrX	77682540	Missense_Mutation	novel	D906N	0.14
BLCA	chrX	77663547	Missense_Mutation	NA	Q1319E	0.56
BLCA	chrX	77600555	Missense_Mutation	rs587778084	N1859S	0.06
BLCA	chrX	77558760	Missense_Mutation	NA	S2138F	0.67
BLCA	chrX	77508619	Missense_Mutation	NA	C2404S	0.42
BRCA	chrX	77683217	In_Frame_Del	novel	D678_E679del	0.13
BRCA	chrX	77681811	Missense_Mutation	novel	I1149V	0.11
BRCA	chrX	77684426	In_Frame_Ins	novel	V277delinsANII	0.11
BRCA	chrX	77684428	In_Frame_Ins	novel	L276delinsFT	0.05
BRCA	chrX	77684087	Missense_Mutation	rs367986587	R390H	0.39
BRCA	chrX	77507247	3'UTR	novel		0.32
BRCA	chrX	77684051	Missense_Mutation	NA	I402N	0.24
BRCA	chrX	77557501	Missense_Mutation	NA	D2217N	0.14
BRCA	chrX	77557561	Missense_Mutation	NA	R2197C	0.27
BRCA	chrX	77682570	Missense_Mutation	NA	D896H	0.33
BRCA	chrX	77693893	Frame_Shift_Del	NA	*D139Mfs14**	0.21
BRCA	chrX	77682269	Missense_Mutation	novel	S996L	0.04
BRCA	chrX	77683289	Missense_Mutation	NA	S656F	0.35
BRCA	chrX	77682827	Missense_Mutation	novel	T810N	0.12
BRCA	chrX	77634615	Missense_Mutation	NA	M1596I	0.2
BRCA	chrX	77684569	Silent	NA	L229L	0.19
BRCA	chrX	77656622	Missense_Mutation	NA	F1384L	0.36
BRCA	chrX	77684516	Missense_Mutation	rs797044865	N247S	0.4
BRCA	chrX	77523352	Missense_Mutation	novel	G2250E	0.04
BRCA	chrX	77682999	Missense_Mutation	NA	D753N	0.03
BRCA	chrX	77682469	Missense_Mutation	rs782283059	E929D	0.19
BRCA	chrX	77717140	Missense_Mutation	NA	Q42E	0.42
BRCA	chrX	77697625	Missense_Mutation	novel	S67F	0.04
BRCA	chrX	77620494	Nonsense_Mutation	novel	K1725*	0.1
BRCA	chrX	77593723	Missense_Mutation	NA	R2028P	0.14
BRCA	chrX	77676296	Missense_Mutation	NA	D1247H	0.3
BRCA	chrX	77717163	Missense_Mutation	novel	S34F	0.07
BRCA	chrX	77599800	Silent	NA	S1906S	0.12
BRCA	chrX	77636050	Nonsense_Mutation	NA	E1522*	0.22
BRCA	chrX	77681864	Missense_Mutation	NA	R1131I	0.22
BRCA	chrX	77682095	Missense_Mutation	NA	S1054F	0.16
BRCA	chrX	77682358	Missense_Mutation	rs138256318	E966D	0.13
BRCA	chrX	77683451	Missense_Mutation	NA	G602D	0.17
BRCA	chrX	77684022	Missense_Mutation	NA	D412Y	0.26
BRCA	chrX	77520894	Nonsense_Mutation	novel	*S2365delinsWLP**	0.05
BRCA	chrX	77693907	Missense_Mutation	novel	L134P	0.07
BRCA	chrX	77683100	Missense_Mutation	NA	S719C	0.28
BRCA	chrX	77681587	Silent	NA	E1223E	0.24
BRCA	chrX	77682736	Frame_Shift_Del	NA	*R840Nfs8**	0.33
BRCA	chrX	77717245	Splice_Site	novel	X7_splice	0.68
BRCA	chrX	77683148	Missense_Mutation	novel	S703C	0.07
CESC	chrX	77600658	Intron	NA		0.21
CESC	chrX	77558847	Splice_Site	NA	X2109_splice	0.63
CESC	chrX	77654139	Nonsense_Mutation	NA	R1426*	0.09
CESC	chrX	77618966	Missense_Mutation	NA	N1763I	0.28
CESC	chrX	77682705	Missense_Mutation	novel	E851K	0.39
CESC	chrX	77557450	Splice_Site	novel	X2233_splice	0.14
CESC	chrX	77505051	3'UTR	novel		0.09
CESC	chrX	77507266	3'UTR	novel		0.15
CESC	chrX	77523365	Missense_Mutation	novel	E2246K	0.06
CESC	chrX	77523366	Frame_Shift_Ins	novel	*K2245Nfs8**	0.06
CESC	chrX	77654118	Frame_Shift_Del	novel	*D1433Ifs57**	0.09
CESC	chrX	77682414	Frame_Shift_Ins	novel	*H948Tfs9**	0.04
CESC	chrX	77508475	Missense_Mutation	novel	Q2452R	0.15
CESC	chrX	77683469	Missense_Mutation	novel	S596F	0.15
CESC	chrX	77683024	Missense_Mutation	NA	M744I	0.28
CESC	chrX	77506196	3'UTR	novel		0.5
CESC	chrX	77507571	3'UTR	novel		0.25
CESC	chrX	77505384	3'UTR	novel		0.5
CESC	chrX	77681820	Missense_Mutation	novel	T1146S	0.3
CESC	chrX	77682232	Missense_Mutation	novel	Q1008H	0.24
CESC	chrX	77683383	Missense_Mutation	NA	E625Q	0.38
CESC	chrX	77683763	Missense_Mutation	NA	R498T	0.21
CESC	chrX	77557484	Missense_Mutation	novel	K2222N	0.2
CESC	chrX	77506661	3'UTR	novel		0.1
CESC	chrX	77505794	3'UTR	novel		0.37
CESC	chrX	77507267	3'UTR	rs782117234		0.36
CESC	chrX	77618841	Missense_Mutation	NA	H1805N	0.32
CESC	chrX	77523301	Missense_Mutation	NA	T2267N	0.4
CESC	chrX	77521486	Nonsense_Mutation	novel	Q2330*	0.28
CESC	chrX	77616499	Intron	novel		0.14
CESC	chrX	77636054	Splice_Region	NA	V1520V	0.58
CESC	chrX	77683181	Missense_Mutation	NA	S692L	0.57
CESC	chrX	77693837	Silent	NA	L157L	0.11
COAD	chrX	77684364	In_Frame_Del	NA	K297del	0.4
COAD	chrX	77684519	Missense_Mutation	NA	R246H	0.21
COAD	chrX	77683971	Missense_Mutation	NA	T429A	0.74
COAD	chrX	77685005	Missense_Mutation	novel	N199T	0.59
COAD	chrX	77786007	5'UTR	novel		0.21
COAD	chrX	77521410	Missense_Mutation	NA	S2355L	0.25
COAD	chrX	77634654	Missense_Mutation	NA	K1583N	0.33
COAD	chrX	77683716	Missense_Mutation	NA	D514Y	0.38
COAD	chrX	77684094	Missense_Mutation	NA	K388Q	0.46
COAD	chrX	77682110	Frame_Shift_Ins	NA	*I1049Nfs4**	0.15
COAD	chrX	77656621	Frame_Shift_Ins	NA	*Q1385Sfs6**	0.26
COAD	chrX	77521421	Missense_Mutation	NA	E2351D	0.79
COAD	chrX	77558764	Missense_Mutation	NA	A2137T	0.42
COAD	chrX	77696660	Missense_Mutation	NA	K96T	0.61
COAD	chrX	77663549	Frame_Shift_Del	NA	*N1318Ifs28**	0.39
COAD	chrX	77508410	Missense_Mutation	NA	R2474C	0.39
COAD	chrX	77683270	Silent	novel	T662T	0.05
COAD	chrX	77599821	Splice_Site	NA	X1900_splice	0.04
COAD	chrX	77654142	Missense_Mutation	NA	R1425G	0.44
COAD	chrX	77682944	Missense_Mutation	rs376906761	A771V	0.56
COAD	chrX	77593805	Missense_Mutation	NA	W2001R	0.45
COAD	chrX	77684146	Silent	rs371831155	Y370Y	0.41
COAD	chrX	77676249	Silent	rs782113542	D1262D	0.33
COAD	chrX	77557587	Missense_Mutation	NA	R2188P	0.18
COAD	chrX	77682357	Nonsense_Mutation	NA	K967*	0.14
COAD	chrX	77683246	Silent	novel	T670T	0.1
COAD	chrX	77599550	Missense_Mutation	novel	K1939N	0.09
COAD	chrX	77508381	Frame_Shift_Del	NA	*P2484Qfs16**	0.08
COAD	chrX	77593742	Missense_Mutation	NA	L2022I	0.32
COAD	chrX	77589836	Missense_Mutation	NA	K2072T	0.26
COAD	chrX	77682564	Missense_Mutation	NA	D898Y	0.36
COAD	chrX	77683047	Missense_Mutation	rs782110483	I737V	0.55
COAD	chrX	77696621	Missense_Mutation	NA	N109T	0.39
COAD	chrX	77593811	Missense_Mutation	NA	P1999S	0.3
COAD	chrX	77684418	Missense_Mutation	NA	C280S	0.24
COAD	chrX	77663395	Silent	NA	R1369R	0.08
COAD	chrX	77681864	Missense_Mutation	NA	R1131I	0.57
COAD	chrX	77523290	Silent	novel	R2271R	0.05
COAD	chrX	77682111	Frame_Shift_Del	NA	I1049*	0.07
COAD	chrX	77682295	Missense_Mutation	novel	K987N	0.31
COAD	chrX	77786046	5'UTR	novel		0.39
COAD	chrX	77682821	Missense_Mutation	NA	S812Y	0.41
COAD	chrX	77663525	Missense_Mutation	novel	S1326L	0.03
COAD	chrX	77633251	Missense_Mutation	NA	S1697N	0.73
COAD	chrX	77664778	Missense_Mutation	NA	R1270S	0.72
COAD	chrX	77681766	Missense_Mutation	NA	D1164N	0.32
COAD	chrX	77520831	Missense_Mutation	novel	R2386Q	0.37
COAD	chrX	77557484	Missense_Mutation	novel	K2222N	0.11
COAD	chrX	77683441	Silent	novel	C605C	0.3
COAD	chrX	77520807	Missense_Mutation	NA	V2394A	0.35
COAD	chrX	77682737	Frame_Shift_Ins	NA	*R840Kfs9**	0.36
COAD	chrX	77683753	Silent	novel	E501E	0.14
COAD	chrX	77693874	Missense_Mutation	novel	E145G	0.01
COAD	chrX	77682278	Frame_Shift_Del	NA	*K993Rfs10**	0.26
ESCA	chrX	77506271	3'UTR	novel		0.42
ESCA	chrX	77507185	3'UTR	novel		0.43
ESCA	chrX	77520847	Missense_Mutation	novel	E2381K	0.22
GBM	chrX	77682819	Missense_Mutation	novel	E813Q	0.12
GBM	chrX	77682578	Missense_Mutation	novel	G893V	0.11
GBM	chrX	77682388	Frame_Shift_Del	novel	*V957Yfs13**	0.93
GBM	chrX	77634658	Frame_Shift_Ins	NA	*T1582Nfs19**	0.44
GBM	chrX	77683163	Frame_Shift_Del	novel	*K698Rfs11**	0.48
GBM	chrX	77681746	Silent	NA	Q1170Q	0.48
GBM	chrX	77682834	Nonsense_Mutation	NA	R808*	0.8
GBM	chrX	77681619	Frame_Shift_Del	novel	*Q1213Rfs4**	0.94
GBM	chrX	77508451	Frame_Shift_Ins	novel	*Y2460Sfs38**	0.21
GBM	chrX	77663532	Missense_Mutation	novel	S1324P	0.09
GBM	chrX	77684469	Missense_Mutation	NA	W263R	0.93
GBM	chrX	77683526	Frame_Shift_Del	novel	*S576Nfs4**	0.25
GBM	chrX	77688885	Frame_Shift_Ins	novel	*Q176Pfs13**	0.13
GBM	chrX	77682202	Missense_Mutation	NA	K1018N	0.39
GBM	chrX	77683038	Nonsense_Mutation	novel	E740*	0.2
GBM	chrX	77663390	Missense_Mutation	NA	R1371T	0.26
GBM	chrX	77508617	Missense_Mutation	novel	V2405I	0.25
GBM	chrX	77520875	Silent	rs782703242	A2371A	0.31
GBM	chrX	77656570	Missense_Mutation	novel	P1402S	0.25
GBM	chrX	77676231	Silent	novel	E1268E	0.21
GBM	chrX	77682191	Missense_Mutation	rs781811015	R1022Q	0.31
GBM	chrX	77682737	Missense_Mutation	rs191682105	R840I	0.28
GBM	chrX	77684181	Silent	novel	L359L	0.24
GBM	chrX	77684508	Nonsense_Mutation	NA	R250*	0.52
GBM	chrX	77599564	Missense_Mutation	novel	K1935E	0.17
GBM	chrX	77688883	Nonsense_Mutation	NA	Q177*	0.85
GBM	chrX	77693829	Missense_Mutation	novel	R160H	0.28
GBM	chrX	77618846	Missense_Mutation	NA	R1803H	0.85
GBM	chrX	77684373	Frame_Shift_Del	novel	*N294Kfs7**	0.96
GBM	chrX	77633299	In_Frame_Del	novel	M1679_I1680del	0.85
GBM	chrX	77682136	Frame_Shift_Del	novel	*D1041Mfs9**	0.81
GBM	chrX	77682597	Frame_Shift_Del	NA	*E886Lfs18**	0.9
GBM	chrX	77558716	Missense_Mutation	NA	R2153C	0.68
GBM	chrX	77520818	Silent	novel	I2390I	0.22
GBM	chrX	77522291	Missense_Mutation	novel	L2316Q	0.06
GBM	chrX	77589891	Missense_Mutation	novel	L2054I	0.35
GBM	chrX	77697629	Missense_Mutation	novel	S66G	0.22
GBM	chrX	77618895	Missense_Mutation	novel	G1787S	0.15
GBM	chrX	77616650	Missense_Mutation	NA	Q1843H	0.75
GBM	chrX	77693858	Missense_Mutation	novel	S150R	0.1
GBM	chrX	77523340	Missense_Mutation	NA	H2254R	0.52
GBM	chrX	77664729	Frame_Shift_Del	novel	*D1287Mfs59**	0.43
GBM	chrX	77664714	Frame_Shift_Del	novel	*S1292Qfs54**	0.29
GBM	chrX	77616699	Frame_Shift_Del	NA	*L1827Cfs9**	0.3
GBM	chrX	77654143	Frame_Shift_Del	novel	*K1424Gfs65**	0.81
GBM	chrX	77593803	Frame_Shift_Del	NA	*W2001Cfs14**	0.74
GBM	chrX	77663418	Nonsense_Mutation	novel	E1362*	0.25
GBM	chrX	77682537	Nonsense_Mutation	NA	R907*	0.91
GBM	chrX	77618846	Missense_Mutation	NA	R1803H	0.95
GBM	chrX	77682607	Frame_Shift_Del	novel	*Q883Rfs13**	0.91
GBM	chrX	77620448	Nonsense_Mutation	NA	S1740*	0.86
HNSC	chrX	77682758	Missense_Mutation	novel	A833D	0.13
HNSC	chrX	77652338	Missense_Mutation	novel	E1445Q	0.5
HNSC	chrX	77683432	Silent	novel	V608V	0.33
HNSC	chrX	77684104	Missense_Mutation	novel	S384R	0.26
HNSC	chrX	77508348	3'UTR	novel		0.19
HNSC	chrX	77599482	Missense_Mutation	novel	S1962F	0.08
HNSC	chrX	77683142	Missense_Mutation	rs781804632	D705G	0.11
HNSC	chrX	77620501	Silent	novel	H1722H	0.83
HNSC	chrX	77634629	Missense_Mutation	novel	L1592F	0.73
HNSC	chrX	77520857	Silent	novel	Q2377Q	0.63
HNSC	chrX	77618932	Silent	novel	K1774K	0.41
HNSC	chrX	77633565	Splice_Site	novel	X1652_splice	0.38
HNSC	chrX	77633566	Splice_Region	novel	E1652E	0.38
HNSC	chrX	77664651	Missense_Mutation	novel	D1313N	0.42
HNSC	chrX	77682914	Missense_Mutation	novel	R781Q	0.51
HNSC	chrX	77616724	Missense_Mutation	novel	D1819H	0.19
HNSC	chrX	77618959	Missense_Mutation	novel	I1765M	0.17
HNSC	chrX	77681639	Missense_Mutation	novel	S1206C	0.05
HNSC	chrX	77682487	Missense_Mutation	novel	K923N	0.14
HNSC	chrX	77682054	Missense_Mutation	novel	T1068A	0.17
HNSC	chrX	77688830	Silent	novel	V194V	0.35
HNSC	chrX	77634649	Missense_Mutation	NA	S1585F	0.12
HNSC	chrX	77682590	Missense_Mutation	novel	S889F	0.08
HNSC	chrX	77683659	Missense_Mutation	novel	E533Q	0.57
HNSC	chrX	77688916	Missense_Mutation	novel	H166N	0.11
HNSC	chrX	77520898	Missense_Mutation	NA	L2364F	0.66
HNSC	chrX	77635957	Missense_Mutation	novel	H1553D	0.67
HNSC	chrX	77682717	Missense_Mutation	novel	F847I	0.37
HNSC	chrX	77558764	Missense_Mutation	NA	A2137T	0.14
HNSC	chrX	77683917	Missense_Mutation	NA	E447K	0.14
HNSC	chrX	77634686	Missense_Mutation	novel	D1573N	0.77
HNSC	chrX	77558786	Silent	novel	A2129A	0.72
HNSC	chrX	77520850	Nonsense_Mutation	novel	Q2380*	0.26
HNSC	chrX	77508605	Frame_Shift_Ins	novel	*L2409Ffs43**	0.03
HNSC	chrX	77508606	Frame_Shift_Ins	novel	*M2410Sfs7**	0.03
HNSC	chrX	77616613	Missense_Mutation	novel	G1856C	0.08
KICH	chrX	77681886	Frame_Shift_Del	novel	*S1124Lfs6**	0.29
KIRC	chrX	77599811	Missense_Mutation	NA	D1903N	0.3
KIRC	chrX	77683392	Missense_Mutation	NA	P622T	0.36
KIRC	chrX	77522310	Missense_Mutation	NA	P2310T	0.19
KIRC	chrX	77682952	Missense_Mutation	NA	K768N	0.08
KIRC	chrX	77683632	Missense_Mutation	NA	V542L	0.1
KIRC	chrX	77557595	Silent	rs781823496	L2185L	0.35
KIRC	chrX	77663549	Frame_Shift_Del	NA	*N1318Ifs28**	0.32
KIRC	chrX	77634694	Missense_Mutation	NA	F1570C	0.34
KIRC	chrX	77620441	Missense_Mutation	NA	R1742S	0.43
KIRC	chrX	77697624	Nonsense_Mutation	novel	*S68Efs2**	0.07
KIRC	chrX	77696681	Missense_Mutation	NA	Y89F	0.58
LAML	chrX	77683232	Missense_Mutation	novel	S675Y	0.08
LAML	chrX	77683176	Missense_Mutation	novel	P694A	0.04
LGG	chrX	77683437	Frame_Shift_Del	novel	*E607Kfs14**	0.36
LGG	chrX	77683564	Frame_Shift_Del	novel	*L563Yfs11**	0.24
LGG	chrX	77557591	Frame_Shift_Ins	novel	*F2187Lfs16**	0.41
LGG	chrX	77682249	Frame_Shift_Del	novel	*V1002Lfs30**	0.81
LGG	chrX	77664668	Frame_Shift_Del	novel	*N1307Mfs39**	0.49
LGG	chrX	77664690	Frame_Shift_Ins	novel	*K1300Efs9**	0.94
LGG	chrX	77654139	Nonsense_Mutation	NA	R1426*	0.34
LGG	chrX	77683981	Frame_Shift_Del	novel	*K425Rfs8**	0.73
LGG	chrX	77683895	Frame_Shift_Del	novel	*K454Rfs16**	0.53
LGG	chrX	77682278	Frame_Shift_Del	NA	*K993Rfs10**	0.14
LGG	chrX	77685008	Splice_Site	NA	X199_splice	0.15
LGG	chrX	77589834	Missense_Mutation	novel	G2073S	0.95
LGG	chrX	77681934	Frame_Shift_Del	novel	*S1108Hfs10**	0.76
LGG	chrX	77684997	Nonsense_Mutation	NA	K202*	0.87
LGG	chrX	77682779	Frame_Shift_Del	novel	*K826Efs4**	0.89
LGG	chrX	77522363	Frame_Shift_Del	novel	*P2292Qfs28**	0.85
LGG	chrX	77676250	Missense_Mutation	NA	D1262G	0.07
LGG	chrX	77600512	Frame_Shift_Ins	novel	*Q1874Pfs8**	0.6
LGG	chrX	77683091	Nonsense_Mutation	novel	S722*	0.04
LGG	chrX	77684004	Nonsense_Mutation	NA	R418*	0.52
LGG	chrX	77683296	Nonsense_Mutation	NA	R654*	0.35
LGG	chrX	77654139	Nonsense_Mutation	NA	R1426*	0.1
LGG	chrX	77682992	Frame_Shift_Del	novel	*N755Mfs13**	0.75
LGG	chrX	77682597	Frame_Shift_Del	NA	*E886Lfs18**	0.69
LGG	chrX	77664772	Silent	novel	A1272A	0.27
LGG	chrX	77684938	Splice_Site	novel	X221_splice	0.2
LGG	chrX	77684545	Frame_Shift_Ins	novel	*N237Kfs23**	0.49
LGG	chrX	77683109	Frame_Shift_Del	novel	*K715Afs4**	0.23
LGG	chrX	77593751	Missense_Mutation	NA	K2019E	0.81
LGG	chrX	77683855	Frame_Shift_Del	novel	*K467Tfs4**	0.63
LGG	chrX	77682110	Frame_Shift_Del	NA	*I1049Kfs69**	0.37
LGG	chrX	77682172	Frame_Shift_Del	novel	*E1017Dfs5**	0.73
LGG	chrX	77633633	Frame_Shift_Ins	novel	*T1630Nfs8**	0.44
LGG	chrX	77684469	Missense_Mutation	NA	W263R	0.52
LGG	chrX	77557467	Missense_Mutation	novel	T2228I	0.42
LGG	chrX	77683186	Frame_Shift_Del	novel	*K690Tfs10**	0.6
LGG	chrX	77684467	Nonsense_Mutation	NA	W263*	0.08
LGG	chrX	77664681	Frame_Shift_Del	novel	*R1302Lfs43**	0.97
LGG	chrX	77558842	Nonsense_Mutation	NA	R2111*	0.68
LGG	chrX	77682597	Frame_Shift_Del	NA	*E886Lfs18**	0.51
LGG	chrX	77654124	Nonsense_Mutation	novel	Q1431*	0.88
LGG	chrX	77684018	Frame_Shift_Del	novel	*L413Kfs20**	0.98
LGG	chrX	77664683	Frame_Shift_Ins	NA	*R1302Kfs7**	0.93
LGG	chrX	77682834	Nonsense_Mutation	NA	R808*	0.67
LGG	chrX	77634704	Splice_Site	NA	X1567_splice	0.22
LGG	chrX	77681985	Frame_Shift_Del	novel	*E1090Rfs27**	0.35
LGG	chrX	77558834	Frame_Shift_Del	novel	*F2113Lfs10**	0.86
LGG	chrX	77684174	Frame_Shift_Del	NA	*I360Rfs6**	0.37
LGG	chrX	77654155	Frame_Shift_Del	novel	*K1420Tfs9**	0.62
LGG	chrX	77684508	Nonsense_Mutation	NA	R250*	0.51
LGG	chrX	77683296	Nonsense_Mutation	NA	R654*	0.7
LGG	chrX	77682245	Frame_Shift_Del	novel	*I1003Kfs29**	0.41
LGG	chrX	77664690	Frame_Shift_Ins	novel	*K1300Efs9**	0.32
LGG	chrX	77684372	Frame_Shift_Del	novel	*K295Rfs4**	0.87
LGG	chrX	77684349	Nonsense_Mutation	novel	E303*	0.51
LGG	chrX	77683862	Nonsense_Mutation	novel	S465*	0.37
LGG	chrX	77684591	Nonsense_Mutation	NA	W222*	0.87
LGG	chrX	77682915	Nonsense_Mutation	NA	R781*	0.79
LGG	chrX	77683257	Frame_Shift_Del	novel	*T662Dfs4**	0.8
LGG	chrX	77684160	Frame_Shift_Del	novel	M366*	0.82
LGG	chrX	77599567	Frame_Shift_Del	novel	*G1934Efs7**	0.78
LGG	chrX	77599545	Frame_Shift_Del	NA	*D1940Vfs14**	0.38
LGG	chrX	77684181	Frame_Shift_Ins	novel	*L359Tfs3**	0.39
LGG	chrX	77633603	Frame_Shift_Del	novel	*K1640Sfs6**	0.82
LGG	chrX	77523328	Frame_Shift_Del	novel	*L2258Gfs10**	0.06
LGG	chrX	77574295	Nonsense_Mutation	NA	S2094*	0.13
LGG	chrX	77523370	Frame_Shift_Ins	novel	*H2244Rfs8**	0.78
LGG	chrX	77654139	Nonsense_Mutation	NA	R1426*	0.53
LGG	chrX	77663487	Frame_Shift_Del	NA	*H1338Qfs11**	0.84
LGG	chrX	77664735	Frame_Shift_Del	novel	*S1285Pfs61**	0.21
LGG	chrX	77683743	Nonsense_Mutation	NA	E505*	0.4
LGG	chrX	77654139	Nonsense_Mutation	NA	R1426*	0.75
LGG	chrX	77557644	Missense_Mutation	NA	G2169E	0.44
LGG	chrX	77633684	Nonsense_Mutation	NA	L1613*	0.28
LGG	chrX	77682537	Frame_Shift_Del	novel	*R907Dfs63**	0.14
LGG	chrX	77684115	Frame_Shift_Del	novel	*S381Qfs33**	0.77
LGG	chrX	77684048	Frame_Shift_Del	novel	*K403Rfs11**	0.64
LGG	chrX	77682537	Nonsense_Mutation	NA	R907*	0.83
LGG	chrX	77633234	Frame_Shift_Del	NA	*E1702Yfs22**	0.84
LGG	chrX	77681546	Nonsense_Mutation	NA	S1237*	0.74
LGG	chrX	77616491	Intron	novel		0.18
LGG	chrX	77664703	Nonsense_Mutation	novel	P1296*	0.47
LGG	chrX	77634614	Frame_Shift_Ins	novel	*G1597Yfs5**	0.29
LGG	chrX	77683162	Frame_Shift_Ins	novel	*D699Gfs2**	0.14
LGG	chrX	77633325	Nonsense_Mutation	NA	W1672*	0.51
LGG	chrX	77599549	Frame_Shift_Ins	novel	*D1940Rfs2**	0.83
LGG	chrX	77557635	Missense_Mutation	NA	E2172G	0.69
LGG	chrX	77663515	Frame_Shift_Del	novel	*E1330Nfs16**	0.09
LGG	chrX	77558842	Nonsense_Mutation	NA	R2111*	0.99
LGG	chrX	77634595	Missense_Mutation	NA	Q1603R	0.75
LGG	chrX	77682509	Frame_Shift_Del	novel	*A916Vfs54**	0.79
LGG	chrX	77683162	Frame_Shift_Ins	novel	*D699Gfs2**	0.67
LGG	chrX	77681985	Frame_Shift_Del	novel	*E1090Rfs27**	0.66
LGG	chrX	77684146	Nonsense_Mutation	novel	Y370*	0.34
LGG	chrX	77683285	Frame_Shift_Del	novel	*R658Vfs2**	0.8
LGG	chrX	77652159	Frame_Shift_Del	novel	*R1504Qfs5**	0.75
LGG	chrX	77620394	Splice_Site	NA	X1757_splice	0.19
LGG	chrX	77557611	Missense_Mutation	NA	V2180A	0.61
LGG	chrX	77663426	Frame_Shift_Del	novel	*K1359Sfs16**	0.36
LGG	chrX	77599550	Frame_Shift_Del	novel	*D1940Ifs15**	0.23
LGG	chrX	77684004	Nonsense_Mutation	NA	R418*	0.26
LGG	chrX	77557543	Nonsense_Mutation	NA	E2203*	0.44
LGG	chrX	77684205	Nonsense_Mutation	NA	E351*	0.36
LGG	chrX	77620443	Missense_Mutation	NA	R1742G	0.79
LGG	chrX	77589941	Splice_Site	NA	X2037_splice	0.77
LGG	chrX	77693925	Missense_Mutation	NA	V128A	0.29
LGG	chrX	77654147	Frame_Shift_Del	novel	*E1413Gfs67**	0.37
LGG	chrX	77684181	Frame_Shift_Ins	novel	*L359Tfs3**	0.41
LGG	chrX	77574322	Missense_Mutation	novel	R2085P	0.85
LGG	chrX	77618957	Frame_Shift_Del	novel	*K1766Rfs16**	0.36
LGG	chrX	77681589	Nonsense_Mutation	NA	E1223*	0.23
LGG	chrX	77558717	Nonsense_Mutation	NA	Y2152*	0.18
LGG	chrX	77688835	Nonsense_Mutation	novel	Q193*	0.19
LGG	chrX	77663548	Frame_Shift_Ins	novel	*N1318Kfs6**	0.91
LGG	chrX	77664684	Frame_Shift_Del	NA	*R1302Efs44**	0.48
LGG	chrX	77683848	Frame_Shift_Del	novel	*V469Ifs44**	0.35
LGG	chrX	77684391	Frame_Shift_Del	novel	*Q289Sfs10**	0.39
LGG	chrX	77684465	Frame_Shift_Del	novel	*Y264Ffs24**	0.7
LGG	chrX	77599571	Frame_Shift_Del	novel	*K1932Gfs21**	0.81
LGG	chrX	77508349	3'UTR	novel		0.14
LGG	chrX	77520875	Silent	rs782703242	A2371A	0.39
LGG	chrX	77620451	Missense_Mutation	NA	R1739Q	0.1
LGG	chrX	77652290	Missense_Mutation	rs782405215	E1461K	0.33
LGG	chrX	77663453	Missense_Mutation	novel	G1350E	0.48
LGG	chrX	77683101	Frame_Shift_Ins	novel	*S719Ifs2**	0.07
LGG	chrX	77684203	Missense_Mutation	novel	E351D	0.38
LGG	chrX	77654139	Nonsense_Mutation	NA	R1426*	0.34
LGG	chrX	77682253	Frame_Shift_Del	NA	V1002*	0.41
LGG	chrX	77685008	Splice_Site	NA	X199_splice	0.91
LGG	chrX	77688863	Frame_Shift_Del	NA	*D184Ifs22**	0.41
LGG	chrX	77683428	Nonsense_Mutation	NA	Q610*	0.73
LGG	chrX	77557587	Missense_Mutation	NA	R2188Q	0.46
LGG	chrX	77684030	Nonsense_Mutation	NA	L409*	0.8
LGG	chrX	77557605	Missense_Mutation	NA	K2182R	0.88
LGG	chrX	77676223	Splice_Region	novel		0.45
LGG	chrX	77634592	Splice_Site	NA	X1603_splice	0.34
LGG	chrX	77656614	Nonsense_Mutation	NA	S1387*	0.63
LGG	chrX	77508334	3'UTR	novel		0.16
LGG	chrX	77620532	Missense_Mutation	novel	G1712D	0.33
LGG	chrX	77682408	Nonsense_Mutation	NA	K950*	0.19
LGG	chrX	77683296	Silent	NA	R654R	0.15
LGG	chrX	77654157	Nonsense_Mutation	novel	K1420*	0.52
LGG	chrX	77508624	Silent	NA	I2402I	0.04
LGG	chrX	77654139	Nonsense_Mutation	NA	R1426*	0.26
LGG	chrX	77685000	Frame_Shift_Ins	novel	*F201Lfs2**	0.47
LGG	chrX	77558782	Nonsense_Mutation	novel	R2131*	0.86
LGG	chrX	77684595	Splice_Site	NA	X221_splice	0.3
LGG	chrX	77683070	Nonsense_Mutation	novel	S729*	0.67
LGG	chrX	77684998	Frame_Shift_Ins	novel	*K202Lfs5**	0.15
LGG	chrX	77682110	Frame_Shift_Ins	NA	*I1049Nfs4**	0.54
LGG	chrX	77682597	Frame_Shift_Del	NA	*E886Lfs18**	0.13
LGG	chrX	77508578	Missense_Mutation	novel	Y2418N	0.36
LGG	chrX	77684422	Frame_Shift_Del	novel	*T278Sfs3**	0.77
LGG	chrX	77684181	Frame_Shift_Ins	novel	*L359Tfs3**	0.4
LGG	chrX	77523304	Frame_Shift_Del	novel	L2266*	0.25
LGG	chrX	77574295	Nonsense_Mutation	NA	S2094*	0.86
LGG	chrX	77682605	Frame_Shift_Del	novel	*Q883Rfs21**	0.73
LGG	chrX	77599761	Frame_Shift_Del	novel	M1920*	0.81
LGG	chrX	77688817	Splice_Site	NA	X198_splice	0.19
LGG	chrX	77682253	Frame_Shift_Del	NA	V1002*	0.94
LGG	chrX	77684437	Frame_Shift_Ins	NA	*L273Ffs9**	0.7
LGG	chrX	77663432	Frame_Shift_Del	novel	*K1357Rfs18**	0.33
LGG	chrX	77696582	Frame_Shift_Del	novel	*P122Qfs5**	0.1
LGG	chrX	77684182	Frame_Shift_Del	NA	*K358Nfs2**	0.45
LGG	chrX	77684183	Missense_Mutation	novel	K358R	0.45
LGG	chrX	77683883	Nonsense_Mutation	novel	S458*	0.91
LGG	chrX	77682592	Frame_Shift_Ins	novel	*S889Lfs8**	0.71
LGG	chrX	77663545	Frame_Shift_Del	novel	*Q1319Rfs4**	0.82
LGG	chrX	77593726	Missense_Mutation	NA	L2027P	0.66
LGG	chrX	77684152	Nonsense_Mutation	novel	*S369Pfs5**	0.84
LGG	chrX	77664683	Frame_Shift_Ins	NA	*R1302Kfs7**	0.73
LGG	chrX	77634634	Missense_Mutation	novel	C1590Y	0.94
LGG	chrX	77557585	Missense_Mutation	NA	V2189L	0.43
LGG	chrX	77684962	Silent	novel	S213S	0.49
LGG	chrX	77593726	Missense_Mutation	NA	L2027P	0.2
LGG	chrX	77684174	Frame_Shift_Del	NA	*I360Rfs6**	0.83
LGG	chrX	77682805	Nonsense_Mutation	novel	Y817*	0.41
LGG	chrX	77600496	Missense_Mutation	NA	L1879V	0.82
LGG	chrX	77618861	Frame_Shift_Ins	novel	*R1798Kfs12**	0.64
LGG	chrX	77684939	Missense_Mutation	NA	R221K	0.37
LGG	chrX	77681865	Missense_Mutation	novel	R1131G	0.47
LGG	chrX	77682537	Frame_Shift_Del	novel	*R907Dfs63**	0.82
LGG	chrX	77682960	Frame_Shift_Ins	novel	*D766Rfs10**	0.69
LGG	chrX	77599582	Splice_Site	novel	X1929_splice	0.77
LGG	chrX	77654160	Frame_Shift_Del	novel	*Q1416Ifs71**	0.22
LGG	chrX	77620452	Nonsense_Mutation	NA	R1739*	0.56
LGG	chrX	77664779	Splice_Site	novel	X1270_splice	0.48
LGG	chrX	77557635	Missense_Mutation	NA	E2172A	0.35
LGG	chrX	77682111	Frame_Shift_Del	NA	I1049*	0.86
LGG	chrX	77682112	Silent	novel	K1048K	0.86
LGG	chrX	77684472	Nonsense_Mutation	NA	Q262*	0.72
LGG	chrX	77683879	Frame_Shift_Ins	novel	*S460Vfs4**	0.27
LGG	chrX	77684064	Frame_Shift_Ins	novel	*V398Cfs4**	0.43
LIHC	chrX	77664690	Missense_Mutation	novel	K1300E	0.74
LIHC	chrX	77682278	Frame_Shift_Del	NA	*K993Rfs10**	0.76
LIHC	chrX	77521441	Missense_Mutation	NA	V2345M	0.45
LIHC	chrX	77682753	Nonsense_Mutation	NA	R835*	0.98
LIHC	chrX	77508282	3'UTR	novel		0.17
LIHC	chrX	77508217	3'UTR	novel		0.38
LIHC	chrX	77600565	Splice_Site	NA	X1856_splice	0.46
LIHC	chrX	77616685	Missense_Mutation	novel	E1832Q	0.87
LIHC	chrX	77682725	Missense_Mutation	NA	T844I	0.36
LIHC	chrX	77683228	Silent	novel	N676N	0.35
LUAD	chrX	77683226	Nonsense_Mutation	NA	S677*	0.28
LUAD	chrX	77683311	Nonsense_Mutation	NA	E649*	0.59
LUAD	chrX	77620479	Missense_Mutation	NA	A1730T	0.18
LUAD	chrX	77599456	Missense_Mutation	NA	D1971Y	0.63
LUAD	chrX	77634679	Missense_Mutation	novel	C1575F	0.19
LUAD	chrX	77683883	Nonsense_Mutation	novel	S458*	0.05
LUAD	chrX	77684473	Silent	NA	N261N	0.1
LUAD	chrX	77682577	Silent	NA	G893G	0.19
LUAD	chrX	77682212	Missense_Mutation	novel	G1015D	0.18
LUAD	chrX	77682839	Missense_Mutation	novel	K806T	0.07
LUAD	chrX	77664672	Missense_Mutation	novel	Q1306K	0.14
LUAD	chrX	77664731	Missense_Mutation	NA	S1286Y	0.17
LUAD	chrX	77717189	Silent	NA	S25S	0.68
LUAD	chrX	77599437	Missense_Mutation	novel	P1977H	0.31
LUAD	chrX	77697595	Missense_Mutation	novel	S77L	0.18
LUAD	chrX	77520856	Missense_Mutation	novel	A2378T	0.14
LUAD	chrX	77681922	Missense_Mutation	novel	T1112A	0.08
LUAD	chrX	77688919	Missense_Mutation	novel	L165V	0.13
LUAD	chrX	77664689	Missense_Mutation	NA	K1300R	0.46
LUAD	chrX	77599488	Nonsense_Mutation	novel	S1960*	0.04
LUAD	chrX	77664646	Missense_Mutation	novel	E1314D	0.23
LUAD	chrX	77664696	Nonsense_Mutation	NA	E1298*	0.31
LUAD	chrX	77684503	Missense_Mutation	NA	K251N	0.42
LUAD	chrX	77522299	Missense_Mutation	NA	L2313F	0.53
LUAD	chrX	77508487	Missense_Mutation	NA	P2448H	0.19
LUAD	chrX	77684002	Silent	NA	R418R	0.39
LUAD	chrX	77682585	Missense_Mutation	novel	A891T	0.35
LUAD	chrX	77652131	Nonsense_Mutation	NA	R1514*	0.13
LUAD	chrX	77682762	Missense_Mutation	NA	G832C	0.06
LUAD	chrX	77599533	Missense_Mutation	NA	G1945E	0.11
LUAD	chrX	77681589	Missense_Mutation	NA	E1223Q	0.07
LUAD	chrX	77652167	Nonsense_Mutation	NA	E1502*	0.46
LUAD	chrX	77683226	Nonsense_Mutation	novel	S677*	0.4
LUAD	chrX	77508274	3'UTR	novel		0.43
LUAD	chrX	77683959	Missense_Mutation	novel	K433E	0.47
LUAD	chrX	77633713	Splice_Site	novel	X1604_splice	0.18
LUAD	chrX	77697583	Missense_Mutation	NA	R81M	0.14
LUAD	chrX	77634666	Silent	NA	V1579V	0.16
LUAD	chrX	77633683	Missense_Mutation	novel	L1613F	0.33
LUAD	chrX	77620410	Missense_Mutation	NA	N1753D	0.15
LUAD	chrX	77652230	Silent	novel	R1481R	0.25
LUAD	chrX	77600475	Missense_Mutation	novel	P1886A	0.24
LUAD	chrX	77684106	Missense_Mutation	novel	S384C	0.65
LUAD	chrX	77620448	Nonsense_Mutation	NA	S1740*	0.17
LUAD	chrX	77634646	Missense_Mutation	NA	P1586Q	0.08
LUAD	chrX	77635985	Silent	NA	E1543E	0.59
LUSC	chrX	77616639	Missense_Mutation	NA	Y1847C	0.36
LUSC	chrX	77681853	Missense_Mutation	NA	R1135W	0.67
LUSC	chrX	77681854	Silent	novel	L1134L	0.49
LUSC	chrX	77599560	Missense_Mutation	NA	K1936T	0.2
LUSC	chrX	77681840	Missense_Mutation	novel	N1139I	0.86
LUSC	chrX	77599476	Missense_Mutation	NA	G1964A	0.05
LUSC	chrX	77520915	Nonsense_Mutation	novel	W2358*	0.11
LUSC	chrX	77683434	Missense_Mutation	NA	V608F	0.47
LUSC	chrX	77508366	Missense_Mutation	NA	Q2488H	0.31
LUSC	chrX	77652120	Silent	novel	L1517L	0.44
LUSC	chrX	77664677	Missense_Mutation	NA	G1304V	0.1
LUSC	chrX	77682680	Missense_Mutation	NA	G859V	0.09
LUSC	chrX	77683166	Missense_Mutation	NA	K697R	0.07
LUSC	chrX	77618918	Missense_Mutation	novel	R1779I	0.14
LUSC	chrX	77616683	Silent	novel	E1832E	0.14
LUSC	chrX	77683013	Missense_Mutation	novel	S748C	0.25
LUSC	chrX	77682691	Missense_Mutation	novel	H855Q	0.34
LUSC	chrX	77683198	Missense_Mutation	NA	K686N	0.3
LUSC	chrX	77684523	Missense_Mutation	novel	L245V	0.46
LUSC	chrX	77683181	Nonsense_Mutation	novel	S692*	0.21
LUSC	chrX	77682066	Missense_Mutation	NA	A1064T	0.1
LUSC	chrX	77682067	Silent	novel	Y1063Y	0.64
LUSC	chrX	77633683	Missense_Mutation	novel	L1613F	0.32
LUSC	chrX	77663557	Splice_Region	NA	E1315E	0.26
LUSC	chrX	77633688	Missense_Mutation	NA	L1612V	0.48
LUSC	chrX	77663491	Missense_Mutation	novel	R1337S	0.83
LUSC	chrX	77634687	Nonsense_Mutation	NA	W1572*	0.23
LUSC	chrX	77684194	Silent	novel	K354K	0.08
LUSC	chrX	77682756	Missense_Mutation	NA	A834T	0.04
MESO	chrX	77683256	Missense_Mutation	rs61752457	P667L	0.65
OV	chrX	77683954	Silent	novel	V434V	0.05
OV	chrX	77508213	3'UTR	novel		0.5
OV	chrX	77620447	Silent	novel	S1740S	0.07
OV	chrX	77663389	Frame_Shift_Del	novel	*R1371Kfs6**	0.17
OV	chrX	77681940	Missense_Mutation	novel	D1106Y	0.22
OV	chrX	77633341	Frame_Shift_Del	novel	*Y1667Sfs13**	0.04
OV	chrX	77654166	Silent	novel	R1417R	0.05
OV	chrX	77684576	Missense_Mutation	novel	G227A	0.03
OV	chrX	77697582	Splice_Site	novel	X81_splice	0.39
OV	chrX	77618939	Missense_Mutation	novel	S1772C	0.07
OV	chrX	77557632	Missense_Mutation	novel	D2173G	0.31
OV	chrX	77574273	Missense_Mutation	novel	E2101D	0.35
OV	chrX	77656563	Missense_Mutation	novel	T1404I	0.1
OV	chrX	77522369	Missense_Mutation	rs368498507	N2290S	0.13
OV	chrX	77684578	Silent	novel	G226G	0.6
OV	chrX	77681807	Missense_Mutation	novel	Q1150L	0.11
OV	chrX	77508625	Missense_Mutation	novel	I2402S	0.06
OV	chrX	77682110	Frame_Shift_Ins	NA	*I1049Nfs4**	0.39
OV	chrX	77684520	Missense_Mutation	rs122445105	R246C	0.46
OV	chrX	77681585	Missense_Mutation	novel	Q1224R	0.64
OV	chrX	77634603	Missense_Mutation	novel	K1600N	0.09
PAAD	chrX	77683463	Missense_Mutation	novel	S598F	0.26
PAAD	chrX	77683318	Silent	novel	L646L	0.06
PAAD	chrX	77683732	Silent	novel	N508N	0.22
PAAD	chrX	77523304	Missense_Mutation	novel	L2266W	0.97
PCPG	chrX	77522363	Frame_Shift_Del	novel	*P2292Qfs28**	0.74
PCPG	chrX	77683771	Frame_Shift_Del	novel	*K495Nfs19**	0.4
PCPG	chrX	77600474	Missense_Mutation	NA	P1886L	0.38
PCPG	chrX	77664683	Frame_Shift_Ins	NA	*R1302Kfs7**	0.63
PCPG	chrX	77682339	Frame_Shift_Del	novel	*D972Rfs30**	0.83
PRAD	chrX	77589902	Missense_Mutation	novel	I2050S	0.59
PRAD	chrX	77683454	Frame_Shift_Del	novel	*S598Rfs3**	0.42
PRAD	chrX	77599758	Missense_Mutation	novel	M1920I	0.41
PRAD	chrX	77635947	Missense_Mutation	NA	M1556T	0.75
READ	chrX	77682559	Silent	rs137974888	T899T	0.17
READ	chrX	77683925	Missense_Mutation	rs781932965	R444Q	0.27
READ	chrX	77688876	Missense_Mutation	rs398123425	N179S	0.63
READ	chrX	77654139	Nonsense_Mutation	NA	R1426*	0.07
READ	chrX	77681573	Missense_Mutation	NA	P1228H	0.79
READ	chrX	77508449	Missense_Mutation	novel	Q2461E	0.13
READ	chrX	77522300	Missense_Mutation	novel	L2313S	0.21
READ	chrX	77616701	Missense_Mutation	novel	F1826L	0.08
READ	chrX	77664753	Nonsense_Mutation	novel	E1279*	0.19
READ	chrX	77508137	3'UTR	novel		0.57
READ	chrX	77682000	Missense_Mutation	novel	A1086T	0.84
READ	chrX	77681612	Missense_Mutation	novel	S1215Y	0.81
READ	chrX	77681755	Missense_Mutation	novel	K1167N	0.07
READ	chrX	77682061	Missense_Mutation	novel	E1065D	0.8
READ	chrX	77682914	Missense_Mutation	novel	R781Q	0.81
READ	chrX	77683950	Missense_Mutation	novel	D436Y	0.81
READ	chrX	77633347	Missense_Mutation	NA	R1665I	0.87
READ	chrX	77683527	Missense_Mutation	NA	K577Q	0.22
READ	chrX	77683803	Missense_Mutation	novel	T485P	0.16
SARC	chrX	77682797	Frame_Shift_Del	novel	*E820Ifs10**	0.53
SARC	chrX	77682874	Frame_Shift_Ins	novel	*K796Qfs4**	0.85
SARC	chrX	77682186	Nonsense_Mutation	NA	E1024*	1
SARC	chrX	77620398	Missense_Mutation	novel	E1757Q	0.31
SARC	chrX	77506292	3'UTR	novel		0.23
SARC	chrX	77616617	Frame_Shift_Ins	novel	*L1854Ffs7**	0.54
SARC	chrX	77618804	Splice_Site	novel	X1816_splice	0.24
SARC	chrX	77682274	Frame_Shift_Del	novel	*K993Nfs9**	0.56
SARC	chrX	77656614	Nonsense_Mutation	NA	S1387*	0.5
SARC	chrX	77593714	Missense_Mutation	novel	E2031V	0.39
SARC	chrX	77683981	Frame_Shift_Del	novel	*K425Rfs8**	0.94
SARC	chrX	77676277	Nonsense_Mutation	novel	S1253*	0.67
SARC	chrX	77620452	Nonsense_Mutation	NA	R1739*	0.4
SARC	chrX	77681671	Frame_Shift_Del	novel	S1174*	0.24
SARC	chrX	77683089	Nonsense_Mutation	novel	E723*	0.62
SARC	chrX	77505759	3'UTR	novel		0.13
SARC	chrX	77600493	Missense_Mutation	novel	S1880C	0.19
SARC	chrX	77654169	Nonsense_Mutation	novel	Q1416*	0.58
SARC	chrX	77634637	Missense_Mutation	novel	G1589E	0.45
SARC	chrX	77684426	Frame_Shift_Ins	novel	*V277Gfs5**	0.54
SARC	chrX	77696595	Frame_Shift_Ins	novel	*M118Yfs19**	0.82
SARC	chrX	77558733	Missense_Mutation	novel	S2147I	0.29
SARC	chrX	77633240	Nonsense_Mutation	novel	K1701*	0.43
SARC	chrX	77654097	Splice_Site	novel	X1439_splice	0.62
SARC	chrX	77683906	Frame_Shift_Del	novel	*R444Lfs19**	0.87
SARC	chrX	77682774	Frame_Shift_Del	novel	M828*	0.8
SARC	chrX	77681557	Frame_Shift_Del	novel	*N1232Sfs15**	0.89
SARC	chrX	77683194	Nonsense_Mutation	novel	K688*	0.49
SARC	chrX	77558747	Frame_Shift_Del	novel	*S2142Mfs24**	0.39
SARC	chrX	77683515	Frame_Shift_Del	novel	*T579Sfs8**	0.93
SARC	chrX	77558798	Frame_Shift_Del	novel	*N2125Wfs2**	0.42
SARC	chrX	77633661	Frame_Shift_Del	novel	*D1618Gfs8**	0.72
SARC	chrX	77684205	Nonsense_Mutation	NA	E351*	0.22
SARC	chrX	77683926	Nonsense_Mutation	novel	R444*	0.92
SARC	chrX	77684467	Nonsense_Mutation	NA	W263*	0.42
SARC	chrX	77507529	3'UTR	novel		0.8
SARC	chrX	77634703	Missense_Mutation	novel	G1567D	0.71
SARC	chrX	77681919	Nonsense_Mutation	novel	E1113*	1
SARC	chrX	77684085	Nonsense_Mutation	novel	Q391*	0.43
SARC	chrX	77682839	Frame_Shift_Del	novel	*K806Rfs16**	0.59
SKCM	chrX	77558777	Silent	novel	V2132V	0.07
SKCM	chrX	77618885	Frame_Shift_Ins	novel	*A1790Vfs21**	0.33
SKCM	chrX	77683925	Missense_Mutation	rs781932965	R444Q	0.31
SKCM	chrX	77682265	Silent	NA	D997D	0.25
SKCM	chrX	77688874	Missense_Mutation	novel	H180Y	0.39
SKCM	chrX	77599447	Missense_Mutation	novel	G1974R	0.14
SKCM	chrX	77635940	Silent	novel	I1558I	0.13
SKCM	chrX	77558716	Missense_Mutation	NA	R2153C	0.8
SKCM	chrX	77683044	Missense_Mutation	novel	L738F	0.85
SKCM	chrX	77521477	Missense_Mutation	NA	E2333K	0.16
SKCM	chrX	77683100	Missense_Mutation	NA	S719F	0.16
SKCM	chrX	77522371	Silent	NA	F2289F	0.59
SKCM	chrX	77683529	Missense_Mutation	NA	S576L	0.2
SKCM	chrX	77682652	Silent	NA	L868L	0.29
SKCM	chrX	77634628	Missense_Mutation	novel	L1592R	0.19
SKCM	chrX	77681827	Silent	NA	K1143K	0.07
SKCM	chrX	77682171	Missense_Mutation	novel	P1029S	0.56
SKCM	chrX	77696658	Missense_Mutation	NA	P97S	0.66
SKCM	chrX	77600509	Missense_Mutation	novel	Q1874H	0.19
SKCM	chrX	77696634	Missense_Mutation	novel	E105K	0.42
SKCM	chrX	77676233	Nonsense_Mutation	NA	E1268*	0.31
SKCM	chrX	77589848	Missense_Mutation	NA	P2068L	0.78
SKCM	chrX	77684255	Missense_Mutation	NA	S334F	0.58
SKCM	chrX	77652212	Missense_Mutation	NA	D1487N	0.24
SKCM	chrX	77589846	Missense_Mutation	novel	L2069F	0.21
SKCM	chrX	77589847	Silent	rs782631268	P2068P	0.21
SKCM	chrX	77676246	Missense_Mutation	NA	D1263E	0.8
SKCM	chrX	77589873	Missense_Mutation	NA	E2060K	0.44
SKCM	chrX	77682984	Missense_Mutation	rs781875244	H758Y	0.07
SKCM	chrX	77656619	Silent	NA	Q1385Q	0.95
SKCM	chrX	77620404	Silent	rs782275081	L1755L	0.89
SKCM	chrX	77682482	Missense_Mutation	NA	S925F	0.85
SKCM	chrX	77557481	Silent	novel	K2223K	0.83
SKCM	chrX	77683695	Missense_Mutation	NA	P521S	0.88
SKCM	chrX	77682132	Missense_Mutation	rs782633384	G1042R	0.17
SKCM	chrX	77684231	Missense_Mutation	NA	S342F	0.41
SKCM	chrX	77652118	Missense_Mutation	novel	R1518K	0.88
SKCM	chrX	77593752	Silent	NA	G2018G	0.28
SKCM	chrX	77684291	Missense_Mutation	NA	S322L	0.19
SKCM	chrX	77664713	Missense_Mutation	NA	S1292L	0.28
STAD	chrX	77664684	Frame_Shift_Del	NA	*R1302Efs44**	0.15
STAD	chrX	77681574	Missense_Mutation	rs782743875	P1228S	0.22
STAD	chrX	77682453	Missense_Mutation	NA	E935K	0.16
STAD	chrX	77508293	3'UTR	novel		0.37
STAD	chrX	77684426	Missense_Mutation	NA	V277A	0.21
STAD	chrX	77599800	Silent	NA	S1906S	0.2
STAD	chrX	77682909	Missense_Mutation	NA	S783R	0.64
STAD	chrX	77684134	Frame_Shift_Ins	novel	*L374Ffs7**	0.14
STAD	chrX	77684219	Missense_Mutation	NA	L346P	0.07
STAD	chrX	77682089	Frame_Shift_Del	novel	*K1056Rfs62**	0.23
STAD	chrX	77633378	Missense_Mutation	novel	E1655K	0.38
STAD	chrX	77676241	Missense_Mutation	rs371187842	N1265S	0.16
STAD	chrX	77682277	Frame_Shift_Ins	novel	*K994Efs6**	0.46
STAD	chrX	77664707	Missense_Mutation	NA	D1294G	0.13
STAD	chrX	77508369	Silent	NA	S2487S	0.11
STAD	chrX	77574350	Frame_Shift_Ins	novel	*K2076Efs7**	0.2
STAD	chrX	77520912	Missense_Mutation	NA	K2359R	0.33
STAD	chrX	77652112	Splice_Site	novel	X1519_splice	0.34
STAD	chrX	77663432	Frame_Shift_Del	novel	*K1357Rfs18**	0.25
STAD	chrX	77682527	Missense_Mutation	NA	K910T	0.28
STAD	chrX	77620464	Missense_Mutation	NA	M1735V	0.11
STAD	chrX	77682689	Missense_Mutation	NA	S856N	0.09
STAD	chrX	77663455	Missense_Mutation	NA	D1349E	0.13
STAD	chrX	77684430	Missense_Mutation	NA	L276V	0.42
STAD	chrX	77663408	Missense_Mutation	NA	E1365A	0.13
STAD	chrX	77684478	Missense_Mutation	NA	N260H	0.11
STAD	chrX	77688866	Silent	rs375794120	Q182Q	0.61
STAD	chrX	77558670	Missense_Mutation	NA	Q2168R	0.35
STAD	chrX	77683017	Missense_Mutation	NA	S747G	0.19
THCA	chrX	77620527	Missense_Mutation	novel	D1714Y	0.3
THCA	chrX	77620463	In_Frame_Ins	novel	A1734_M1735insK	0.08
THCA	chrX	77620465	Frame_Shift_Ins	novel	*M1735Dfs21**	0.07
THCA	chrX	77684361	Missense_Mutation	NA	K299E	0.1
THYM	chrX	77505810	3'UTR	novel		0.74
THYM	chrX	77507318	3'UTR	novel		0.26
THYM	chrX	77508293	3'UTR	novel		0.4
UCEC	chrX	77635952	Silent	novel	R1554R	0.21
UCEC	chrX	77683415	Missense_Mutation	NA	G614D	0.62
UCEC	chrX	77652282	Silent	NA	E1463E	0.47
UCEC	chrX	77635975	Nonsense_Mutation	NA	E1547*	0.36
UCEC	chrX	77681699	Missense_Mutation	novel	R1186I	0.24
UCEC	chrX	77682119	Missense_Mutation	NA	S1046I	0.23
UCEC	chrX	77682697	Missense_Mutation	NA	E853D	0.29
UCEC	chrX	77652284	Missense_Mutation	rs782295246	E1463K	0.33
UCEC	chrX	77505099	3'UTR	novel		0.4
UCEC	chrX	77558688	Missense_Mutation	NA	V2162A	0.13
UCEC	chrX	77683503	Nonsense_Mutation	NA	E585*	0.19
UCEC	chrX	77684477	Missense_Mutation	novel	N260S	0.39
UCEC	chrX	77688836	Silent	novel	L192L	0.21
UCEC	chrX	77507185	3'UTR	novel		0.42
UCEC	chrX	77682111	Frame_Shift_Del	NA	I1049*	0.44
UCEC	chrX	77558767	Missense_Mutation	NA	D2136N	0.35
UCEC	chrX	77589914	Missense_Mutation	NA	S2046Y	0.33
UCEC	chrX	77683195	Silent	NA	E687E	0.43
UCEC	chrX	77684269	Missense_Mutation	novel	K329N	0.07
UCEC	chrX	77505880	3'UTR	novel		0.5
UCEC	chrX	77506276	3'UTR	rs782655614		0.32
UCEC	chrX	77684096	Missense_Mutation	novel	T387I	0.33
UCEC	chrX	77717163	Missense_Mutation	novel	S34Y	0.12
UCEC	chrX	77681946	Missense_Mutation	novel	R1104G	0.14
UCEC	chrX	77520898	Missense_Mutation	NA	L2364I	0.24
UCEC	chrX	77620451	Missense_Mutation	NA	R1739Q	0.45
UCEC	chrX	77681744	Missense_Mutation	NA	R1171I	0.17
UCEC	chrX	77683672	Missense_Mutation	NA	I528M	0.41
UCEC	chrX	77685007	Splice_Site	NA	X199_splice	0.44
UCEC	chrX	77717182	Nonsense_Mutation	NA	E28*	0.43
UCEC	chrX	77682205	Silent	novel	E1017E	0.36
UCEC	chrX	77507770	3'UTR	novel		0.48
UCEC	chrX	77508319	3'UTR	novel		0.28
UCEC	chrX	77599747	Missense_Mutation	NA	S1924F	0.46
UCEC	chrX	77523290	Missense_Mutation	rs122445112	R2271G	0.45
UCEC	chrX	77682101	Missense_Mutation	novel	K1052T	0.31
UCEC	chrX	77664773	Missense_Mutation	novel	A1272D	0.38
UCEC	chrX	77682914	Missense_Mutation	novel	R781Q	0.42
UCEC	chrX	77683954	Silent	novel	V434V	0.4
UCEC	chrX	77684205	Nonsense_Mutation	NA	E351*	0.37
UCEC	chrX	77688845	Silent	novel	H189H	0.37
UCEC	chrX	77505264	3'UTR	novel		0.19
UCEC	chrX	77507547	3'UTR	novel		0.17
UCEC	chrX	77508610	Missense_Mutation	novel	R2407Q	0.32
UCEC	chrX	77593739	Missense_Mutation	novel	L2023I	0.34
UCEC	chrX	77620416	Missense_Mutation	novel	L1751F	0.08
UCEC	chrX	77681659	Missense_Mutation	novel	D1199E	0.11
UCEC	chrX	77682900	Missense_Mutation	novel	S786P	0.19
UCEC	chrX	77507955	3'UTR	novel		0.38
UCEC	chrX	77574302	Missense_Mutation	novel	A2092T	0.46
UCEC	chrX	77593781	Missense_Mutation	novel	A2009T	0.45
UCEC	chrX	77599542	Missense_Mutation	novel	S1942N	0.43
UCEC	chrX	77786133	5'UTR	novel		0.41
UCEC	chrX	77507455	3'UTR	novel		0.24
UCEC	chrX	77636050	Nonsense_Mutation	NA	E1522*	0.2
UCEC	chrX	77682542	Missense_Mutation	novel	R905I	0.12
UCEC	chrX	77683381	Missense_Mutation	novel	E625D	0.34
UCEC	chrX	77574271	Missense_Mutation	NA	F2102C	0.47
UCEC	chrX	77599499	Missense_Mutation	novel	K1956N	0.27
UCEC	chrX	77682007	Missense_Mutation	novel	K1083N	0.32
UCEC	chrX	77697607	Missense_Mutation	novel	S73F	0.09
UCEC	chrX	77589855	Missense_Mutation	novel	D2066Y	0.04
UCEC	chrX	77682256	Missense_Mutation	NA	K1000N	0.2
UCEC	chrX	77684401	Silent	novel	E285E	0.05
UCEC	chrX	77558814	Missense_Mutation	NA	G2120E	0.18
UCEC	chrX	77663455	Silent	rs199625659	D1349D	0.21
UCEC	chrX	77786157	5'UTR	novel		0.2
UCEC	chrX	77683886	Missense_Mutation	NA	I457N	0.49
UCEC	chrX	77593729	Missense_Mutation	NA	I2026T	0.4
UCEC	chrX	77635974	Missense_Mutation	NA	E1547G	0.23
UCEC	chrX	77652335	Nonsense_Mutation	NA	E1446*	0.17
UCEC	chrX	77654135	Missense_Mutation	rs781849044	R1427H	0.12
UCEC	chrX	77664769	Silent	NA	K1273K	0.25
UCEC	chrX	77681592	Missense_Mutation	rs782520515	D1222N	0.11
UCEC	chrX	77682560	Missense_Mutation	rs782757975	T899M	0.15
UCEC	chrX	77683617	Missense_Mutation	rs782760045	D547N	0.33
UCEC	chrX	77682152	Missense_Mutation	novel	I1035S	0.15
UCEC	chrX	77682268	Silent	novel	S996S	0.17
UCEC	chrX	77684383	Silent	novel	L291L	0.16
UCEC	chrX	77698584	Missense_Mutation	novel	S60N	0.18
UCEC	chrX	77682537	Nonsense_Mutation	NA	R907*	0.31
UCEC	chrX	77507993	3'UTR	novel		0.16
UCEC	chrX	77682564	Missense_Mutation	novel	D898N	0.26
UCEC	chrX	77593796	Missense_Mutation	NA	D2004Y	0.49
UCEC	chrX	77616693	Missense_Mutation	NA	P1829L	0.39
UCEC	chrX	77558768	Silent	rs148659669	F2135F	0.35
UCEC	chrX	77682838	Missense_Mutation	novel	K806N	0.4
UCEC	chrX	77683207	Missense_Mutation	novel	E683D	0.45
UCEC	chrX	77682738	Frame_Shift_Del	novel	*R840Efs29**	0.26
UCEC	chrX	77681851	Frame_Shift_Ins	novel	*E1136Tfs13**	0.07
UCEC	chrX	77507185	3'UTR	novel		0.6
UCEC	chrX	77508202	3'UTR	novel		0.44
UCEC	chrX	77506388	3'UTR	novel		0.42
UCEC	chrX	77558733	Missense_Mutation	novel	S2147I	0.08
UCEC	chrX	77616509	Intron	novel		0.46
UCEC	chrX	77618843	Missense_Mutation	NA	A1804V	0.46
UCEC	chrX	77681728	Missense_Mutation	novel	K1176N	0.49
UCEC	chrX	77682767	Missense_Mutation	novel	K830T	0.37
UCEC	chrX	77682914	Missense_Mutation	novel	R781Q	0.4
UCEC	chrX	77683120	Silent	novel	K712K	0.38
UCEC	chrX	77683295	Missense_Mutation	NA	R654Q	0.67
UCEC	chrX	77683700	Missense_Mutation	novel	S519Y	0.46
UCEC	chrX	77683894	Missense_Mutation	novel	K454N	0.35
UCEC	chrX	77786158	5'UTR	novel		0.27
UCEC	chrX	77505005	3'UTR	novel		0.13
UCEC	chrX	77506377	3'UTR	novel		0.41
UCEC	chrX	77507986	3'UTR	novel		0.14
UCEC	chrX	77508329	3'UTR	novel		0.38
UCEC	chrX	77681612	Missense_Mutation	novel	S1215Y	0.35
UCEC	chrX	77683747	Missense_Mutation	novel	Q503H	0.14
UCEC	chrX	77506983	3'UTR	novel		0.33
UCEC	chrX	77522298	Missense_Mutation	novel	G2314R	0.29
UCEC	chrX	77664743	Missense_Mutation	novel	A1282V	0.17
UCEC	chrX	77683284	Missense_Mutation	novel	R658C	0.37
UCEC	chrX	77683783	Silent	novel	G491G	0.37
UCEC	chrX	77504997	3'UTR	novel		0.28
UCEC	chrX	77523317	Nonsense_Mutation	novel	E2262*	0.23
UCEC	chrX	77505580	3'UTR	rs188467001		0.32
UCEC	chrX	77506735	3'UTR	novel		0.33
UCEC	chrX	77522294	Missense_Mutation	novel	A2315V	0.35
UCEC	chrX	77633248	Missense_Mutation	novel	R1698Q	0.42
UCEC	chrX	77656611	Missense_Mutation	novel	G1388E	0.26
UCEC	chrX	77683859	Missense_Mutation	novel	R466I	0.4
UCEC	chrX	77786195	5'UTR	novel		0.13
UCEC	chrX	77684223	Missense_Mutation	rs149249195	A345T	0.29
UCEC	chrX	77506636	3'UTR	novel		0.41
UCEC	chrX	77505676	3'UTR	novel		0.39
UCEC	chrX	77507307	3'UTR	novel		0.17
UCEC	chrX	77507727	3'UTR	novel		0.14
UCEC	chrX	77521462	Missense_Mutation	novel	A2338T	0.31
UCEC	chrX	77684394	Nonsense_Mutation	NA	E288*	0.48
UCEC	chrX	77507101	3'UTR	novel		0.8
UCEC	chrX	77558768	Silent	rs148659669	F2135F	0.14
UCEC	chrX	77574340	Missense_Mutation	novel	R2079Q	0.4
UCEC	chrX	77633242	Missense_Mutation	novel	L1700R	0.47
UCEC	chrX	77633575	Missense_Mutation	novel	E1649D	0.29
UCEC	chrX	77652160	Missense_Mutation	novel	R1504Q	0.38
UCEC	chrX	77654139	Nonsense_Mutation	NA	R1426*	0.24
UCEC	chrX	77684114	Missense_Mutation	novel	S381L	0.33
UCEC	chrX	77506223	3'UTR	novel		0.25
UCEC	chrX	77507255	3'UTR	novel		0.46
UCEC	chrX	77557482	Missense_Mutation	novel	K2223T	0.4
UCEC	chrX	77682951	Missense_Mutation	novel	T769P	0.37
UCEC	chrX	77684342	Missense_Mutation	novel	S305N	0.37
UCEC	chrX	77684182	Frame_Shift_Del	NA	*K358Nfs2**	0.38
UCEC	chrX	77508183	3'UTR	novel		0.31
UCEC	chrX	77618879	Missense_Mutation	NA	S1792Y	0.4
UCEC	chrX	77633256	Silent	novel	V1695V	0.41
UCEC	chrX	77634652	Missense_Mutation	novel	K1584T	0.44
UCEC	chrX	77652306	Missense_Mutation	novel	E1455D	0.57
UCEC	chrX	77682775	Silent	novel	S827S	0.45
UCEC	chrX	77683503	Nonsense_Mutation	NA	E585*	0.3
UCEC	chrX	77507937	3'UTR	novel		0.49
UCEC	chrX	77508283	3'UTR	novel		0.2
UCEC	chrX	77681873	Missense_Mutation	novel	R1128I	0.29
UCEC	chrX	77618847	Missense_Mutation	NA	R1803C	0.45
UCEC	chrX	77683717	Silent	novel	L513L	0.45
UCEC	chrX	77508202	3'UTR	rs782769672		0.53
UCEC	chrX	77558768	Silent	rs148659669	F2135F	0.43
UCEC	chrX	77618879	Missense_Mutation	NA	S1792Y	0.3
UCEC	chrX	77654156	Missense_Mutation	NA	K1420T	0.45
UCEC	chrX	77682382	Missense_Mutation	NA	Q958H	0.2
UCEC	chrX	77683503	Nonsense_Mutation	NA	E585*	0.44
UCEC	chrX	77684161	Missense_Mutation	NA	N365K	0.2
UCEC	chrX	77697592	Missense_Mutation	NA	R78Q	0.35
UCEC	chrX	77618890	Silent	novel	Q1788Q	0.06
UCEC	chrX	77682029	Missense_Mutation	NA	S1076C	0.43
UCEC	chrX	77507272	3'UTR	novel		0.32
UCEC	chrX	77507700	3'UTR	novel		0.24
UCEC	chrX	77508503	Missense_Mutation	novel	N2443H	0.27
UCEC	chrX	77574306	Silent	novel	T2090T	0.36
UCEC	chrX	77682905	Missense_Mutation	novel	S784Y	0.2
UCEC	chrX	77683452	Missense_Mutation	novel	G602C	0.37
UCEC	chrX	77684533	Missense_Mutation	novel	K241N	0.38
UCEC	chrX	77717216	Missense_Mutation	novel	Q16H	0.58
UCEC	chrX	77505569	3'UTR	novel		0.5
UCEC	chrX	77505863	3'UTR	novel		0.23
UCEC	chrX	77506696	3'UTR	novel		0.45
UCEC	chrX	77507185	3'UTR	novel		0.52
UCEC	chrX	77508202	3'UTR	novel		0.43
UCEC	chrX	77558800	Missense_Mutation	novel	N2125D	0.34
UCEC	chrX	77618868	Missense_Mutation	novel	D1796N	0.12
UCEC	chrX	77652288	Silent	novel	E1461E	0.33
UCEC	chrX	77618848	Frame_Shift_Del	NA	*K1802Nfs10**	0.09
UCEC	chrX	77507185	3'UTR	novel		0.53
UCEC	chrX	77506222	3'UTR	novel		0.3
UCEC	chrX	77506565	3'UTR	novel		0.2
UCEC	chrX	77507058	3'UTR	novel		0.38
UCEC	chrX	77507897	3'UTR	novel		0.15
UCEC	chrX	77508296	3'UTR	novel		0.24
UCEC	chrX	77558720	Silent	novel	V2151V	0.4
UCEC	chrX	77620492	Missense_Mutation	novel	K1725N	0.33
UCEC	chrX	77656585	Missense_Mutation	rs782228142	E1397K	0.13
UCEC	chrX	77681848	Missense_Mutation	novel	E1136D	0.08
UCEC	chrX	77684102	Missense_Mutation	novel	S385Y	0.14
UCEC	chrX	77507185	3'UTR	novel		0.41
UCEC	chrX	77506219	3'UTR	novel		0.37
UCEC	chrX	77663472	Missense_Mutation	novel	K1344E	0.39
UCEC	chrX	77505580	3'UTR	novel		0.35
UCEC	chrX	77681579	Missense_Mutation	NA	I1226T	0.42
UCEC	chrX	77684419	Silent	novel	A279A	0.08
UCEC	chrX	77599821	Splice_Site	novel	X1900_splice	0.1
UCEC	chrX	77508306	3'UTR	novel		0.36
UCEC	chrX	77558768	Silent	rs148659669	F2135F	0.4
UCEC	chrX	77593802	Missense_Mutation	novel	Y2002H	0.33
UCEC	chrX	77663478	Missense_Mutation	rs781810958	R1342W	0.28
UCEC	chrX	77681941	Missense_Mutation	novel	Q1105H	0.23
UCEC	chrX	77682360	Nonsense_Mutation	novel	E966*	0.21
UCEC	chrX	77683542	Nonsense_Mutation	novel	G572*	0.24
UCEC	chrX	77574280	Missense_Mutation	novel	A2099G	0.09
UCEC	chrX	77574282	Nonsense_Mutation	novel	W2098*	0.09
UCEC	chrX	77505671	3'UTR	novel		0.47
UCEC	chrX	77506177	3'UTR	novel		0.29
UCEC	chrX	77506758	3'UTR	novel		0.35
UCEC	chrX	77574341	Nonsense_Mutation	NA	R2079*	0.33
UCEC	chrX	77652160	Missense_Mutation	novel	R1504Q	0.35
UCEC	chrX	77664679	Silent	novel	T1303T	0.38
UCEC	chrX	77682929	Missense_Mutation	novel	K776T	0.26
UCEC	chrX	77684087	Missense_Mutation	rs367986587	R390H	0.25
UCEC	chrX	77684500	Missense_Mutation	novel	E252D	0.39
UCEC	chrX	77717195	Silent	NA	A23A	0.49
UCEC	chrX	77557526	Silent	novel	Y2208Y	0.39
UCEC	chrX	77505137	3'UTR	novel		0.4
UCEC	chrX	77507550	3'UTR	novel		0.08
UCEC	chrX	77616701	Missense_Mutation	novel	F1826L	0.11
UCEC	chrX	77682560	Missense_Mutation	rs782757975	T899M	0.31
UCEC	chrX	77507321	3'UTR	novel		0.21
UCEC	chrX	77507970	3'UTR	novel		0.45
UCEC	chrX	77620451	Missense_Mutation	NA	R1739Q	0.43
UCEC	chrX	77508202	3'UTR	novel		0.33
UCEC	chrX	77506073	3'UTR	novel		0.47
UCEC	chrX	77506303	3'UTR	novel		0.42
UCEC	chrX	77508274	3'UTR	novel		0.33
UCEC	chrX	77558781	Missense_Mutation	rs122445101	R2131Q	0.44
UCEC	chrX	77656626	Missense_Mutation	NA	D1383A	0.47
UCEC	chrX	77681917	Missense_Mutation	novel	E1113D	0.04
UCEC	chrX	77682720	Missense_Mutation	NA	D846Y	0.43
UCEC	chrX	77682891	Missense_Mutation	novel	D789Y	0.05
UCEC	chrX	77683503	Nonsense_Mutation	NA	E585*	0.06
UCEC	chrX	77717138	Missense_Mutation	NA	Q42H	0.22
UCEC	chrX	77505878	3'UTR	novel		0.33
UCEC	chrX	77506591	3'UTR	novel		0.24
UCEC	chrX	77636050	Nonsense_Mutation	NA	E1522*	0.11
UCEC	chrX	77652230	Missense_Mutation	NA	R1481W	0.1
UCEC	chrX	77682102	Missense_Mutation	novel	K1052Q	0.14
UCEC	chrX	77697616	Missense_Mutation	novel	K70T	0.11
UCEC	chrX	77684224	Silent	rs143491422	S344S	0.48
UCEC	chrX	77558815	Nonsense_Mutation	novel	G2120*	0.29
UCEC	chrX	77681831	Nonsense_Mutation	novel	S1142*	0.19
UCEC	chrX	77717136	Missense_Mutation	NA	N43S	0.2
UCEC	chrX	77599757	Missense_Mutation	novel	S1921C	0.1
UCEC	chrX	77682515	Missense_Mutation	NA	A914V	0.3
UCEC	chrX	77504926	3'UTR	novel		0.23
UCEC	chrX	77507459	3'UTR	novel		0.42
UCEC	chrX	77620474	Silent	novel	V1731V	0.33
UCEC	chrX	77681978	Missense_Mutation	novel	R1093M	0.24
UCEC	chrX	77682196	Silent	novel	P1020P	0.14
UCEC	chrX	77508228	3'UTR	novel		0.31
UCEC	chrX	77574327	Silent	novel	Y2083Y	0.3
UCEC	chrX	77600472	Missense_Mutation	novel	W1887R	0.38
UCEC	chrX	77682725	Missense_Mutation	NA	T844I	0.43
UCEC	chrX	77656605	Missense_Mutation	novel	S1390T	0.26
UCEC	chrX	77656606	Missense_Mutation	novel	S1390C	0.27
UCEC	chrX	77633678	Missense_Mutation	NA	D1615G	0.5
UCEC	chrX	77652221	Missense_Mutation	NA	L1484I	0.39
UCEC	chrX	77654137	Silent	NA	R1426R	0.42
UCEC	chrX	77664696	Nonsense_Mutation	NA	E1298*	0.45
UCEC	chrX	77682657	Missense_Mutation	NA	N867H	0.15
UCEC	chrX	77682849	Missense_Mutation	NA	I803L	0.42
UCEC	chrX	77682914	Missense_Mutation	novel	R781Q	0.38
UCEC	chrX	77633608	Silent	NA	F1638F	0.12
UCEC	chrX	77683435	Missense_Mutation	NA	E607D	0.26
UCEC	chrX	77599550	Frame_Shift_Del	novel	*D1940Ifs15**	0.23
UCEC	chrX	77616465	Intron	novel		0.38
UCEC	chrX	77633317	Missense_Mutation	NA	D1675G	0.3
UCEC	chrX	77634649	Missense_Mutation	novel	S1585Y	0.05
UCEC	chrX	77664683	Missense_Mutation	NA	R1302I	0.27
UCEC	chrX	77682815	Missense_Mutation	NA	S814Y	0.33
UCEC	chrX	77693837	Silent	novel	L157L	0.32
UCEC	chrX	77681553	Silent	NA	L1235L	0.03
UCEC	chrX	77508306	3'UTR	novel		0.31
UCEC	chrX	77557454	Silent	NA	P2232P	0.3
UCEC	chrX	77620532	Missense_Mutation	novel	G1712D	0.12
UCEC	chrX	77508446	Missense_Mutation	novel	P2462S	0.34
UCEC	chrX	77682022	Missense_Mutation	novel	E1078D	0.39
UCEC	chrX	77505000	3'UTR	novel		0.39
UCEC	chrX	77507891	3'UTR	novel		0.47
UCEC	chrX	77681825	Missense_Mutation	novel	R1144I	0.42
UCEC	chrX	77684274	Nonsense_Mutation	novel	E328*	0.32
UCEC	chrX	77682630	Missense_Mutation	novel	S876P	0.4
UCEC	chrX	77684088	Missense_Mutation	rs150484080	R390C	0.45
UCEC	chrX	77507185	3'UTR	novel		0.69
UCEC	chrX	77507652	3'UTR	novel		0.28
UCEC	chrX	77616715	Missense_Mutation	NA	A1822T	0.28
UCEC	chrX	77683139	Missense_Mutation	NA	S706N	0.13
UCEC	chrX	77684181	Frame_Shift_Ins	novel	*L359Tfs3**	0.41
UCEC	chrX	77508535	Missense_Mutation	NA	T2432I	0.25
UCEC	chrX	77507342	3'UTR	novel		0.46
UCEC	chrX	77507661	3'UTR	novel		0.32
UCEC	chrX	77599747	Missense_Mutation	NA	S1924F	0.45
UCEC	chrX	77682253	Missense_Mutation	novel	K1001N	0.39
UCEC	chrX	77684315	Missense_Mutation	novel	R314K	0.42
UCEC	chrX	77506423	3'UTR	novel		0.38
UCEC	chrX	77681738	Missense_Mutation	novel	S1173L	0.3
UCEC	chrX	77682914	Missense_Mutation	novel	R781Q	0.33
UCEC	chrX	77683910	Missense_Mutation	novel	P449H	0.39
UCEC	chrX	77684351	Missense_Mutation	novel	S302I	0.42
UCEC	chrX	77684584	Silent	rs782223625	A224A	0.36
UCEC	chrX	77688879	Missense_Mutation	novel	V178A	0.55
UCS	chrX	77633637	Missense_Mutation	novel	N1629D	0.39
UCS	chrX	77557536	Missense_Mutation	novel	T2205N	0.15
UCS	chrX	77633249	Missense_Mutation	novel	R1698W	0.14
UCS	chrX	77652130	Missense_Mutation	novel	R1514Q	0.09

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
LGG	DEL	0.0643	1.4358e-07
SARC	DEL	0.3307	2.7116e-16
THCA	DEL	0	0.21991

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0001	Kaplan-Meier Survival Analysis
ACC	0.025	Kaplan-Meier Survival Analysis
SKCM	0.00011	Kaplan-Meier Survival Analysis
BRCA	0.033	Kaplan-Meier Survival Analysis
ESCA	0.0017	Kaplan-Meier Survival Analysis
PCPG	0.041	Kaplan-Meier Survival Analysis
KICH	0.026	Kaplan-Meier Survival Analysis
UCEC	0.036	Kaplan-Meier Survival Analysis
LIHC	0.019	Kaplan-Meier Survival Analysis
LGG	0.027	Kaplan-Meier Survival Analysis
OV	0.034	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBPome

Literatures

Expression

Transcripts

Gene Model

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742