EuRBPDB

Description

Ensembl ID: ENSG00000086712 (Gene tree)
Gene ID: 55787
Gene Symbol: TXLNG
Alias: FLJ11209|LSR5|FIAT|MGC126621|MGC126625|TXLNGX|CXorf15
Full Name: taxilin gamma
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 58,093 bases
Position: chrX:16,786,427-16,844,519
Accession: 18578
RBP type: non-canonical RBP
Summary: This gene encodes a member of the taxilin family. The encoded protein binds to the C-terminal coiled-coil region of syntaxin family members 1A, 3A and 4A, and may play a role in intracellular vesicle trafficking. This gene is up-regulated by lipopolysaccharide and the gene product may be involved in cell cycle regulation. The related mouse protein was also shown to inhibit activating transcription factor 4-mediated transcription and thus regulate bone mass accrual. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000485153	TXLNG-203	3231	-	-	- (aa)	-	-
ENST00000398155	TXLNG-202	3998	XM_017029631	ENSP00000381222	396 (aa)	XP_016885120	Q9NUQ3
ENST00000380122	TXLNG-201	4401	XM_024452398	ENSP00000369465	528 (aa)	XP_024308166	Q9NUQ3

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000086712	Prostate-Specific Antigen	3E-13	28139693

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000086712	rs5969745	X	16812550	?	Prostate-specific antigen levels (conditioned on lead SNPs)	28139693	unit increase	0.03	EFO_0004624

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005829	cytosol	-	ISS	Component
GO:0007049	cell cycle	-	IEA	Process
GO:0010564	regulation of cell cycle process	18068885.	IMP	Process
GO:0019905	syntaxin binding	-	IEA	Function
GO:0030500	regulation of bone mineralization	-	ISS	Process
GO:0031965	nuclear membrane	15911876.	IDA	Component
GO:0046982	protein heterodimerization activity	15911876.	IDA	Function
GO:0051726	regulation of cell cycle	-	ISS	Process