EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000087995 (Gene tree)
Gene ID: 339175
Gene Symbol: METTL2A
Alias: FLJ12760|METTL2
Full Name: methyltransferase like 2A
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 26,956 bases
Position: chr17:62,423,867-62,450,822
Accession: 25755
RBP type: canonical RBP
Summary: (Methyltransferase Like 2A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include methyltransferase activity and tRNA (cytosine) methyltransferase activity. An important paralog of this gene is METTL2B.

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000309610	Methyltransf_31	PF13847.6	3.2e-09	1	1
ENSP00000479905	Methyltransf_31	PF13847.6	3.2e-09	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000311506	METTL2A-201	2537	XM_017024572	ENSP00000309610	378 (aa)	XP_016880061	Q96IZ6
ENST00000582027	METTL2A-203	572	-	-	- (aa)	-	-
ENST00000333483	METTL2A-202	1556	-	-	- (aa)	-	-
ENST00000616852	METTL2A-204	3150	-	ENSP00000479905	313 (aa)	-	A0A087WW35

Gene Model

Click here to download ENSG00000087995's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000087995's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000087995	METTL2A	100	98.722	ENSG00000165055	METTL2B	100	98.722

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000087995	METTL2A	99	67.638	ENSAPOG00000019825	mettl2a	90	66.667	Acanthochromis_polyacanthus
ENSG00000087995	METTL2A	100	87.335	ENSAMEG00000004032	-	100	87.335	Ailuropoda_melanoleuca
ENSG00000087995	METTL2A	99	62.581	ENSACIG00000009574	mettl2a	90	62.810	Amphilophus_citrinellus
ENSG00000087995	METTL2A	99	66.990	ENSAOCG00000012765	mettl2a	89	66.022	Amphiprion_ocellaris
ENSG00000087995	METTL2A	99	66.667	ENSAPEG00000003799	mettl2a	89	65.746	Amphiprion_percula
ENSG00000087995	METTL2A	99	65.696	ENSATEG00000000903	mettl2a	91	66.295	Anabas_testudineus
ENSG00000087995	METTL2A	97	68.167	ENSAPLG00000005374	-	96	65.470	Anas_platyrhynchos
ENSG00000087995	METTL2A	96	63.344	ENSACAG00000016823	-	95	63.836	Anolis_carolinensis
ENSG00000087995	METTL2A	96	65.781	ENSACLG00000001776	mettl2a	96	64.986	Astatotilapia_calliptera
ENSG00000087995	METTL2A	97	64.686	ENSAMXG00000015090	mettl2a	86	65.169	Astyanax_mexicanus
ENSG00000087995	METTL2A	99	85.577	ENSBTAG00000009458	METTL2A	99	85.224	Bos_taurus
ENSG00000087995	METTL2A	100	96.178	ENSCJAG00000033545	-	100	96.178	Callithrix_jacchus
ENSG00000087995	METTL2A	81	87.296	ENSCAFG00000013365	-	73	87.296	Canis_familiaris
ENSG00000087995	METTL2A	99	89.423	ENSCAFG00020026820	-	100	88.391	Canis_lupus_dingo
ENSG00000087995	METTL2A	98	82.468	ENSTSYG00000002783	-	99	82.468	Carlito_syrichta
ENSG00000087995	METTL2A	99	84.936	ENSCPOG00000003808	-	100	83.113	Cavia_porcellus
ENSG00000087995	METTL2A	100	97.771	ENSCATG00000007364	-	100	97.771	Cercocebus_atys
ENSG00000087995	METTL2A	99	84.295	ENSCLAG00000004955	-	97	83.113	Chinchilla_lanigera
ENSG00000087995	METTL2A	100	96.834	ENSCSAG00000003846	-	100	96.834	Chlorocebus_sabaeus
ENSG00000087995	METTL2A	98	68.158	ENSCPBG00000012298	-	97	68.895	Chrysemys_picta_bellii
ENSG00000087995	METTL2A	100	96.815	ENSCANG00000027777	-	100	96.815	Colobus_angolensis_palliatus
ENSG00000087995	METTL2A	100	80.739	ENSCGRG00001023089	Mettl2	98	80.739	Cricetulus_griseus_chok1gshd
ENSG00000087995	METTL2A	99	81.090	ENSCGRG00000003381	Mettl2	95	81.871	Cricetulus_griseus_crigri
ENSG00000087995	METTL2A	97	66.007	ENSCSEG00000016579	mettl2a	87	66.292	Cynoglossus_semilaevis
ENSG00000087995	METTL2A	97	66.997	ENSCVAG00000012179	mettl2a	91	66.292	Cyprinodon_variegatus
ENSG00000087995	METTL2A	97	66.885	ENSDARG00000008105	mettl2a	91	66.944	Danio_rerio
ENSG00000087995	METTL2A	99	86.218	ENSDNOG00000043251	-	100	84.697	Dasypus_novemcinctus
ENSG00000087995	METTL2A	83	84.674	ENSDORG00000028245	Mettl2	99	83.648	Dipodomys_ordii
ENSG00000087995	METTL2A	98	89.902	ENSEASG00005010594	-	97	87.968	Equus_asinus_asinus
ENSG00000087995	METTL2A	98	90.228	ENSECAG00000018804	-	97	88.235	Equus_caballus
ENSG00000087995	METTL2A	97	65.132	ENSELUG00000017635	mettl2a	89	65.826	Esox_lucius
ENSG00000087995	METTL2A	100	89.490	ENSFCAG00000010931	-	100	89.490	Felis_catus
ENSG00000087995	METTL2A	97	68.387	ENSFALG00000008097	-	97	68.035	Ficedula_albicollis
ENSG00000087995	METTL2A	99	83.121	ENSFDAG00000014414	-	99	83.121	Fukomys_damarensis
ENSG00000087995	METTL2A	97	65.064	ENSFHEG00000013086	mettl2a	89	64.658	Fundulus_heteroclitus
ENSG00000087995	METTL2A	97	64.686	ENSGMOG00000000193	mettl2a	96	64.265	Gadus_morhua
ENSG00000087995	METTL2A	98	67.412	ENSGALG00000000396	METTL2A	98	66.398	Gallus_gallus
ENSG00000087995	METTL2A	97	65.686	ENSGACG00000009023	mettl2a	93	66.571	Gasterosteus_aculeatus
ENSG00000087995	METTL2A	99	67.576	ENSGAGG00000000748	-	99	68.976	Gopherus_agassizii
ENSG00000087995	METTL2A	96	66.113	ENSHBUG00000023834	mettl2a	91	65.819	Haplochromis_burtoni
ENSG00000087995	METTL2A	97	66.337	ENSHCOG00000005928	mettl2a	91	66.667	Hippocampus_comes
ENSG00000087995	METTL2A	97	65.017	ENSIPUG00000024192	mettl2a	93	63.957	Ictalurus_punctatus
ENSG00000087995	METTL2A	100	86.053	ENSSTOG00000010289	-	100	86.053	Ictidomys_tridecemlineatus
ENSG00000087995	METTL2A	99	82.637	ENSJJAG00000017179	Mettl2	100	81.217	Jaculus_jaculus
ENSG00000087995	METTL2A	97	66.997	ENSKMAG00000020718	mettl2a	93	65.301	Kryptolebias_marmoratus
ENSG00000087995	METTL2A	97	68.167	ENSLOCG00000011314	mettl2a	92	67.033	Lepisosteus_oculatus
ENSG00000087995	METTL2A	98	85.993	ENSLAFG00000011224	-	97	86.072	Loxodonta_africana
ENSG00000087995	METTL2A	100	97.771	ENSMFAG00000007048	METTL2A	100	97.771	Macaca_fascicularis
ENSG00000087995	METTL2A	100	97.771	ENSMMUG00000009802	METTL2A	100	97.771	Macaca_mulatta
ENSG00000087995	METTL2A	100	97.452	ENSMLEG00000037621	-	100	97.452	Mandrillus_leucophaeus
ENSG00000087995	METTL2A	97	68.317	ENSMAMG00000022236	mettl2a	88	68.258	Mastacembelus_armatus
ENSG00000087995	METTL2A	96	65.781	ENSMZEG00005022838	mettl2a	91	65.537	Maylandia_zebra
ENSG00000087995	METTL2A	97	67.846	ENSMGAG00000001245	-	98	67.045	Meleagris_gallopavo
ENSG00000087995	METTL2A	100	81.217	ENSMAUG00000008120	Mettl2	98	81.217	Mesocricetus_auratus
ENSG00000087995	METTL2A	100	90.415	ENSMICG00000044781	-	100	90.415	Microcebus_murinus
ENSG00000087995	METTL2A	99	79.947	ENSMOCG00000017424	Mettl2	97	79.947	Microtus_ochrogaster
ENSG00000087995	METTL2A	99	77.460	ENSMODG00000010257	-	100	76.440	Monodelphis_domestica
ENSG00000087995	METTL2A	97	65.017	ENSMALG00000007761	mettl2a	89	65.730	Monopterus_albus
ENSG00000087995	METTL2A	100	78.307	MGP_CAROLIEiJ_G0017298	Mettl2	95	78.307	Mus_caroli
ENSG00000087995	METTL2A	100	79.420	ENSMUSG00000020691	Mettl2	95	79.420	Mus_musculus
ENSG00000087995	METTL2A	100	79.420	MGP_SPRETEiJ_G0018141	Mettl2	95	79.420	Mus_spretus
ENSG00000087995	METTL2A	99	87.781	ENSMLUG00000011972	-	99	85.185	Myotis_lucifugus
ENSG00000087995	METTL2A	96	65.894	ENSNBRG00000019764	mettl2a	91	65.634	Neolamprologus_brichardi
ENSG00000087995	METTL2A	99	98.071	ENSNLEG00000007529	-	100	98.071	Nomascus_leucogenys
ENSG00000087995	METTL2A	99	82.803	ENSODEG00000008990	-	100	82.803	Octodon_degus
ENSG00000087995	METTL2A	98	79.545	ENSODEG00000000055	-	99	79.545	Octodon_degus
ENSG00000087995	METTL2A	96	66.113	ENSONIG00000000977	mettl2a	91	65.537	Oreochromis_niloticus
ENSG00000087995	METTL2A	99	69.872	ENSOANG00000000934	-	97	66.667	Ornithorhynchus_anatinus
ENSG00000087995	METTL2A	96	81.215	ENSOCUG00000011591	-	96	81.215	Oryctolagus_cuniculus
ENSG00000087995	METTL2A	97	66.337	ENSORLG00000003321	mettl2a	91	66.011	Oryzias_latipes
ENSG00000087995	METTL2A	97	66.667	ENSORLG00020009352	mettl2a	91	66.011	Oryzias_latipes_hni
ENSG00000087995	METTL2A	97	66.667	ENSORLG00015002215	mettl2a	98	66.011	Oryzias_latipes_hsok
ENSG00000087995	METTL2A	97	66.447	ENSOMEG00000022489	-	94	65.429	Oryzias_melastigma
ENSG00000087995	METTL2A	99	90.385	ENSOGAG00000014790	-	100	88.918	Otolemur_garnettii
ENSG00000087995	METTL2A	99	83.905	ENSOARG00000012110	-	94	83.905	Ovis_aries
ENSG00000087995	METTL2A	99	88.462	ENSPPRG00000004162	-	99	88.462	Panthera_pardus
ENSG00000087995	METTL2A	99	88.710	ENSPTIG00000013790	-	98	88.673	Panthera_tigris_altaica
ENSG00000087995	METTL2A	100	98.148	ENSPTRG00000019664	-	100	98.148	Pan_troglodytes
ENSG00000087995	METTL2A	100	98.083	ENSPTRG00000009504	METTL2A	100	98.083	Pan_troglodytes
ENSG00000087995	METTL2A	100	97.452	ENSPANG00000021128	-	100	97.452	Papio_anubis
ENSG00000087995	METTL2A	83	83.684	ENSPSIG00000011888	-	94	83.684	Pelodiscus_sinensis
ENSG00000087995	METTL2A	97	65.260	ENSPMGG00000002653	mettl2a	92	63.904	Periophthalmus_magnuspinnatus
ENSG00000087995	METTL2A	99	81.613	ENSPEMG00000011277	Mettl2	98	81.167	Peromyscus_maniculatus_bairdii
ENSG00000087995	METTL2A	96	59.532	ENSPMAG00000007098	mettl2a	91	58.357	Petromyzon_marinus
ENSG00000087995	METTL2A	97	68.421	ENSPFOG00000009811	mettl2a	92	67.787	Poecilia_formosa
ENSG00000087995	METTL2A	97	68.092	ENSPLAG00000022249	mettl2a	92	67.507	Poecilia_latipinna
ENSG00000087995	METTL2A	97	68.421	ENSPMEG00000002599	mettl2a	92	67.507	Poecilia_mexicana
ENSG00000087995	METTL2A	100	98.681	ENSPPYG00000008952	-	100	98.681	Pongo_abelii
ENSG00000087995	METTL2A	100	90.415	ENSPCOG00000022425	-	100	90.415	Propithecus_coquereli
ENSG00000087995	METTL2A	100	88.391	ENSPVAG00000005571	-	100	88.391	Pteropus_vampyrus
ENSG00000087995	METTL2A	96	66.113	ENSPNYG00000011885	mettl2a	90	65.819	Pundamilia_nyererei
ENSG00000087995	METTL2A	93	79.944	ENSRNOG00000006131	Mettl2b	100	79.944	Rattus_norvegicus
ENSG00000087995	METTL2A	100	97.771	ENSRBIG00000033312	-	100	97.771	Rhinopithecus_bieti
ENSG00000087995	METTL2A	100	97.771	ENSRROG00000033706	-	100	97.771	Rhinopithecus_roxellana
ENSG00000087995	METTL2A	99	77.143	ENSSHAG00000002924	-	100	75.393	Sarcophilus_harrisii
ENSG00000087995	METTL2A	97	65.347	ENSSFOG00015023376	mettl2a	89	65.027	Scleropages_formosus
ENSG00000087995	METTL2A	96	65.449	ENSSMAG00000009808	mettl2a	91	63.760	Scophthalmus_maximus
ENSG00000087995	METTL2A	98	67.320	ENSSDUG00000022754	mettl2a	94	67.131	Seriola_dumerili
ENSG00000087995	METTL2A	98	66.993	ENSSLDG00000002078	mettl2a	90	66.852	Seriola_lalandi_dorsalis
ENSG00000087995	METTL2A	97	70.701	ENSSPUG00000009791	-	85	70.845	Sphenodon_punctatus
ENSG00000087995	METTL2A	98	66.667	ENSSPAG00000015837	mettl2a	89	66.111	Stegastes_partitus
ENSG00000087995	METTL2A	99	87.781	ENSSSCG00000033421	-	99	87.781	Sus_scrofa
ENSG00000087995	METTL2A	97	66.775	ENSTGUG00000003112	-	99	66.864	Taeniopygia_guttata
ENSG00000087995	METTL2A	98	64.610	ENSTRUG00000016340	mettl2a	91	64.543	Takifugu_rubripes
ENSG00000087995	METTL2A	97	67.105	ENSTNIG00000011723	mettl2a	88	66.947	Tetraodon_nigroviridis
ENSG00000087995	METTL2A	99	89.103	ENSTTRG00000012619	-	100	87.863	Tursiops_truncatus
ENSG00000087995	METTL2A	95	80.992	ENSUAMG00000022066	-	76	80.992	Ursus_americanus
ENSG00000087995	METTL2A	71	92.825	ENSUMAG00000016063	-	99	92.825	Ursus_maritimus
ENSG00000087995	METTL2A	99	89.711	ENSVVUG00000005506	-	80	88.360	Vulpes_vulpes
ENSG00000087995	METTL2A	97	63.487	ENSXETG00000007856	mettl2b	82	63.333	Xenopus_tropicalis
ENSG00000087995	METTL2A	97	67.105	ENSXMAG00000008640	mettl2a	88	64.516	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0016427	tRNA (cytosine) methyltransferase activity	-	ISS	Function
GO:0030488	tRNA methylation	-	ISS	Process
GO:0052735	tRNA (cytosine-3-)-methyltransferase activity	21873635.	IBA	Function