EuRBPDB

Description

RBPome

Expression

Transcripts

Gene Model

PPI

Gene Ontology

Description

Ensembl ID: ENSG00000090061 (Gene tree)
Gene ID: 8812
Gene Symbol: CCNK
Alias: CPR4
Full Name: cyclin K
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 53,876 bases
Position: chr14:99,481,169-99,535,044
Accession: 1596
RBP type: non-canonical RBP
Summary: The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities. [provided by RefSeq, Jul 2008]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000556641	CCNK-207	747	-	-	- (aa)	-	-
ENST00000557441	CCNK-209	936	-	ENSP00000450792	227 (aa)	-	G3V2Q3
ENST00000389879	CCNK-201	3524	XM_005268154	ENSP00000374529	580 (aa)	XP_005268211	O75909
ENST00000553636	CCNK-202	546	-	-	- (aa)	-	-
ENST00000557165	CCNK-208	955	-	-	- (aa)	-	-
ENST00000555842	CCNK-205	811	-	ENSP00000450440	109 (aa)	-	G3V235
ENST00000555049	CCNK-204	1606	-	ENSP00000452307	378 (aa)	-	G3V5E1
ENST00000555942	CCNK-206	206	-	-	- (aa)	-	-
ENST00000553865	CCNK-203	5627	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000090061's gene model file

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000090061's network

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000079	regulation of cyclin-dependent protein serine/threonine kinase activity	9632813.	TAS	Process
GO:0002944	cyclin K-CDK12 complex	22012619.	IPI	Component
GO:0002945	cyclin K-CDK13 complex	22012619.	IPI	Component
GO:0004693	cyclin-dependent protein serine/threonine kinase activity	9632813.	IDA	Function
GO:0005515	protein binding	16189514.16713569.25416956.26748711.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0006357	regulation of transcription by RNA polymerase II	21873635.	IBA	Process
GO:0006366	transcription by RNA polymerase II	-	TAS	Process
GO:0006368	transcription elongation from RNA polymerase II promoter	-	TAS	Process
GO:0006468	protein phosphorylation	-	IEA	Process
GO:0006974	cellular response to DNA damage stimulus	22012619.	IMP	Process
GO:0007049	cell cycle	-	IEA	Process
GO:0008024	cyclin/CDK positive transcription elongation factor complex	21873635.	IBA	Component
GO:0008353	RNA polymerase II CTD heptapeptide repeat kinase activity	9632813.	IDA	Function
GO:0016538	cyclin-dependent protein serine/threonine kinase regulator activity	21873635.	IBA	Function
GO:0019901	protein kinase binding	22012619.	IPI	Function
GO:0032786	positive regulation of DNA-templated transcription, elongation	21873635.	IBA	Process
GO:0042795	snRNA transcription by RNA polymerase II	-	TAS	Process
GO:0044828	negative regulation by host of viral genome replication	21555514.	IDA	Process
GO:0045737	positive regulation of cyclin-dependent protein serine/threonine kinase activity	-	IEA	Process
GO:0045944	positive regulation of transcription by RNA polymerase II	-	TAS	Process
GO:0051301	cell division	-	IEA	Process
GO:0061575	cyclin-dependent protein serine/threonine kinase activator activity	21873635.	IBA	Function
GO:0071157	negative regulation of cell cycle arrest	9632813.	IGI	Process
GO:2001165	positive regulation of phosphorylation of RNA polymerase II C-terminal domain serine 2 residues	22988298.	IMP	Process