EuRBPDB

Description

Ensembl ID: ENSG00000090273 (Gene tree)
Gene ID: 10726
Gene Symbol: NUDC
Alias: NudC
Full Name: nuclear distribution C, dynein complex regulator
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 46,634 bases
Position: chr1:26,900,238-26,946,871
Accession: 8045
RBP type: non-canonical RBP
Summary: This gene encodes a nuclear distribution protein that plays an essential role in mitosis and cytokinesis. The encoded protein is involved in spindle formation during mitosis and in microtubule organization during cytokinesis. Pseudogenes of this gene are found on chromosome 2. [provided by RefSeq, Feb 2012]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000452707	NUDC-203	816	-	ENSP00000400981	133 (aa)	-	A0A0A0MSS4
ENST00000435827	NUDC-202	821	-	ENSP00000404020	186 (aa)	-	A0A0A0MSU9
ENST00000321265	NUDC-201	1800	XM_011540530	ENSP00000319664	331 (aa)	XP_011538832	Q9Y266
ENST00000484772	NUDC-204	607	-	-	- (aa)	-	-

Gene Model

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000090273	rs182050989	1	26936054	T	Plateletcrit	27863252	[0.056-0.099] unit increase	0.07717716	EFO_0007985
ENSG00000090273	rs182050989	1	26936054	?	Systolic blood pressure	30595370			EFO_0006335

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000090273	NUDC	98	52.870	FBgn0021768	nudC	99	52.870	Drosophila_melanogaster
ENSG00000090273	NUDC	100	92.169	ENSMUSG00000028851	Nudc	100	91.867	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005515	protein binding	22159412.25036637.26638075.27173435.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	25468996.	IDA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0005874	microtubule	-	IEA	Component
GO:0006457	protein folding	21873635.	IBA	Process
GO:0007049	cell cycle	-	IEA	Process
GO:0007275	multicellular organism development	10210332.	TAS	Process
GO:0008283	cell proliferation	10210332.	TAS	Process
GO:0032502	developmental process	21873635.	IBA	Process
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0051082	unfolded protein binding	21873635.	IBA	Function
GO:0051301	cell division	-	IEA	Process