EuRBPDB

Description

Ensembl ID: ENSG00000090615 (Gene tree)
Gene ID: 2802
Gene Symbol: GOLGA3
Alias: golgin-160|GCP170|MEA-2
Full Name: golgin A3
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 60,210 bases
Position: chr12:132,768,909-132,829,118
Accession: 4426
RBP type: non-canonical RBP
Summary: The Golgi apparatus, which participates in glycosylation and transport of proteins and lipids in the secretory pathway, consists of a series of stacked cisternae (flattened membrane sacs). Interactions between the Golgi and microtubules are thought to be important for the reorganization of the Golgi after it fragments during mitosis. This gene encodes a member of the golgin family of proteins which are localized to the Golgi. Its encoded protein has been postulated to play a role in nuclear transport and Golgi apparatus localization. Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene. [provided by RefSeq, Feb 2010]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000541013	GOLGA3-206	498	-	ENSP00000479170	84 (aa)	-	A0A087WV43
ENST00000204726	GOLGA3-201	9252	XM_024448940	ENSP00000204726	1498 (aa)	XP_024304708	Q08378
ENST00000456883	GOLGA3-203	5496	-	ENSP00000409303	1390 (aa)	-	Q08378
ENST00000537317	GOLGA3-205	298	-	-	- (aa)	-	-
ENST00000534967	GOLGA3-204	484	-	-	- (aa)	-	-
ENST00000545875	GOLGA3-207	3784	-	ENSP00000442603	1134 (aa)	-	Q08378
ENST00000450791	GOLGA3-202	8870	XM_005266164	ENSP00000410378	1498 (aa)	XP_005266221	Q08378

Gene Model

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000090615	Alcoholism	8.89163e-005	22978509
ENSG00000090615	Coronary Artery Disease	3.1560000E-005	-
ENSG00000090615	Triiodothyronine	1.8830000E-006	-
ENSG00000090615	Triiodothyronine	3.0150000E-005	-
ENSG00000090615	Glioma	4E-8	26424050
ENSG00000090615	Vaccine Potency	3E-7	22542470
ENSG00000090615	Glioma	4E-6	26424050

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000090615	rs199559944	12	132784756	?	Cognitive empathy	28584286	[0.069-0.172] unit decrease	0.1205	EFO_0009183
ENSG00000090615	rs55806229	12	132788599	T	Cognitive empathy	28584286	[0.096-0.241] unit decrease	0.1682	EFO_0009183
ENSG00000090615	rs55825300	12	132794637	?	Cognitive empathy	28584286	[0.1-0.25] unit decrease	0.1738	EFO_0009183
ENSG00000090615	rs111696067	12	132799954	A	Glioma	26424050	[1.08-1.20]	1.1235955	EFO_0000326
ENSG00000090615	rs111696067	12	132799954	A	Non-glioblastoma glioma	26424050	[1.12-1.27]	1.1904762	EFO_0000326
ENSG00000090615	rs74531549	12	132785584	A	Self-reported math ability	30038396	[0.013-0.024] unit decrease	0.0182	EFO_0004875
ENSG00000090615	rs77330849	12	132798319	T	Self-reported math ability (MTAG)	30038396	[0.011-0.022] unit increase	0.0165	EFO_0004875
ENSG00000090615	rs12282	12	132769223	?	Immune response to smallpox vaccine (IL-6)	22542470			EFO_0004645
ENSG00000090615	rs2291256	12	132816737	T	Smoking status (ever vs never smokers)	30643258	[0.014-0.028] unit increase	0.02076341	EFO_0004318
ENSG00000090615	rs11611651	12	132804204	A	Smoking initiation (ever regular vs never regular) (MTAG)	30643251	[0.0094-0.017] unit increase	0.0131882	EFO_0006527
ENSG00000090615	rs11611651	12	132804204	A	Smoking initiation (ever regular vs never regular)	30643251	[0.018-0.036] unit increase	0.027114276	EFO_0006527

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000139	Golgi membrane	9295333.	TAS	Component
GO:0005215	transporter activity	8315394.	NAS	Function
GO:0005515	protein binding	14522980.	IPI	Function
GO:0005634	nucleus	-	IDA	Component
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005730	nucleolus	-	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005794	Golgi apparatus	21873635.	IBA	Component
GO:0005794	Golgi apparatus	-	IDA	Component
GO:0005829	cytosol	14522980.	IDA	Component
GO:0006891	intra-Golgi vesicle-mediated transport	8315394.	NAS	Process
GO:0007283	spermatogenesis	-	IEA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0017119	Golgi transport complex	21873635.	IBA	Component
GO:0017119	Golgi transport complex	8315394.	IDA	Component
GO:0032580	Golgi cisterna membrane	-	IEA	Component
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0090498	extrinsic component of Golgi membrane	14522980.	IDA	Component