EuRBPDB

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000090621 (Gene tree)
Gene ID: 8761
Gene Symbol: PABPC4
Alias: iPABP|APP-1
Full Name: poly(A) binding protein cytoplasmic 4
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 16,037 bases
Position: chr1:39,560,813-39,576,849
Accession: 8557
RBP type: canonical RBP
Summary: Poly(A)-binding proteins (PABPs) bind to the poly(A) tail present at the 3-prime ends of most eukaryotic mRNAs. PABPC4 or IPABP (inducible PABP) was isolated as an activation-induced T-cell mRNA encoding a protein. Activation of T cells increased PABPC4 mRNA levels in T cells approximately 5-fold. PABPC4 contains 4 RNA-binding domains and proline-rich C terminus. PABPC4 is localized primarily to the cytoplasm. It is suggested that PABPC4 might be necessary for regulation of stability of labile mRNA species in activated T cells. PABPC4 was also identified as an antigen, APP1 (activated-platelet protein-1), expressed on thrombin-activated rabbit platelets. PABPC4 may also be involved in the regulation of protein translation in platelets and megakaryocytes or may participate in the binding or stabilization of polyadenylates in platelet dense granules. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000408559	PABP	PF00658.18	4.1e-31	1	1
ENSP00000398267	PABP	PF00658.18	4.7e-31	1	1
ENSP00000361953	PABP	PF00658.18	5.7e-31	1	1
ENSP00000361947	PABP	PF00658.18	6e-31	1	1
ENSP00000361948	PABP	PF00658.18	6.4e-31	1	1
ENSP00000361949	PABP	PF00658.18	6.8e-31	1	1
ENSP00000436407	PABP	PF00658.18	3.9e-19	1	1
ENSP00000361953	RRM_5	PF13893.6	1.6e-08	1	1
ENSP00000361947	RRM_5	PF13893.6	1.8e-08	1	1
ENSP00000361948	RRM_5	PF13893.6	2.1e-08	1	1
ENSP00000361949	RRM_5	PF13893.6	2.3e-08	1	1
ENSP00000398267	RRM_5	PF13893.6	1.6e-06	1	2
ENSP00000398267	RRM_5	PF13893.6	1.6e-06	2	2
ENSP00000361953	RRM_1	PF00076.22	1.3e-91	1	4
ENSP00000361953	RRM_1	PF00076.22	1.3e-91	2	4
ENSP00000361953	RRM_1	PF00076.22	1.3e-91	3	4
ENSP00000361953	RRM_1	PF00076.22	1.3e-91	4	4
ENSP00000361947	RRM_1	PF00076.22	1.5e-91	1	4
ENSP00000361947	RRM_1	PF00076.22	1.5e-91	2	4
ENSP00000361947	RRM_1	PF00076.22	1.5e-91	3	4
ENSP00000361947	RRM_1	PF00076.22	1.5e-91	4	4
ENSP00000361948	RRM_1	PF00076.22	1.7e-91	1	4
ENSP00000361948	RRM_1	PF00076.22	1.7e-91	2	4
ENSP00000361948	RRM_1	PF00076.22	1.7e-91	3	4
ENSP00000361948	RRM_1	PF00076.22	1.7e-91	4	4
ENSP00000361949	RRM_1	PF00076.22	1.9e-91	1	4
ENSP00000361949	RRM_1	PF00076.22	1.9e-91	2	4
ENSP00000361949	RRM_1	PF00076.22	1.9e-91	3	4
ENSP00000361949	RRM_1	PF00076.22	1.9e-91	4	4
ENSP00000398267	RRM_1	PF00076.22	1e-68	1	3
ENSP00000398267	RRM_1	PF00076.22	1e-68	2	3
ENSP00000398267	RRM_1	PF00076.22	1e-68	3	3
ENSP00000431383	RRM_1	PF00076.22	7.9e-37	1	2
ENSP00000431383	RRM_1	PF00076.22	7.9e-37	2	2
ENSP00000406675	RRM_1	PF00076.22	4.3e-28	1	2
ENSP00000406675	RRM_1	PF00076.22	4.3e-28	2	2
ENSP00000436566	RRM_1	PF00076.22	9.8e-20	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
9030741	Identification and structure of activated-platelet protein-1, a protein with RNA-binding domain motifs that is expressed by activated platelets.	Eur J Biochem	1997 Jan 15	Houng AK	-
8524242	iPABP, an inducible poly(A)-binding protein detected in activated human T cells.	Mol Cell Biol	1995 Dec	Yang H	-
14717712	Human PABP binds AU-rich RNA via RNA-binding domains 3 and 4.	Eur J Biochem	2004 Jan	Sladic RT	-
23938467	Linking spermatid ribonucleic acid (RNA) binding protein and retrogene diversity to reproductive success.	Mol Cell Proteomics	2013 Nov	Chapman KM	doi: 10.1074/mcp.M113.030585
26005159	Gender-specific association between the cytoplasmic poly(A) binding protein 4 rs4660293 single nucleotide polymorphism and serum lipid levels.	Mol Med Rep	2015 Sep	Wu J	doi: 10.3892/mmr.2015.3823
22884093	Cytoplasmic poly(A) binding protein 4 is highly expressed in human colorectal cancer and correlates with better prognosis.	J Genet Genomics	2012 Aug 20	Liu D	doi: 10.1016/j.jgg.2012.05.007

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000531243	PABPC4-225	532	-	ENSP00000436698	4 (aa)	-	UPI0003F47D46
ENST00000525045	PABPC4-219	765	-	-	- (aa)	-	-
ENST00000482028	PABPC4-213	633	-	-	- (aa)	-	-
ENST00000468476	PABPC4-209	3592	-	-	- (aa)	-	-
ENST00000492519	PABPC4-217	323	-	-	- (aa)	-	-
ENST00000451091	PABPC4-207	898	-	ENSP00000406675	129 (aa)	-	B1ANR1
ENST00000470443	PABPC4-210	1212	-	ENSP00000436391	112 (aa)	-	H0YEQ8
ENST00000529216	PABPC4-223	317	-	-	- (aa)	-	-
ENST00000372856	PABPC4-201	3016	-	ENSP00000361947	631 (aa)	-	Q13310
ENST00000461578	PABPC4-208	193	-	-	- (aa)	-	-
ENST00000525751	PABPC4-221	556	-	-	- (aa)	-	-
ENST00000477556	PABPC4-212	413	-	-	- (aa)	-	-
ENST00000372862	PABPC4-204	2470	-	ENSP00000361953	615 (aa)	-	B1ANR0
ENST00000527718	PABPC4-222	746	-	ENSP00000436566	249 (aa)	-	H0YEU6
ENST00000530186	PABPC4-224	352	-	ENSP00000436407	68 (aa)	-	H0YER0
ENST00000421687	PABPC4-205	1663	-	ENSP00000398267	550 (aa)	-	H0Y5F5
ENST00000483770	PABPC4-214	476	-	-	- (aa)	-	-
ENST00000484555	PABPC4-215	450	-	-	- (aa)	-	-
ENST00000437136	PABPC4-206	876	-	ENSP00000408559	195 (aa)	-	H0Y6X6
ENST00000474378	PABPC4-211	591	-	ENSP00000431383	197 (aa)	-	H0YCC8
ENST00000372857	PABPC4-202	3048	-	ENSP00000361948	644 (aa)	-	Q13310
ENST00000513632	PABPC4-218	738	-	-	- (aa)	-	-
ENST00000492468	PABPC4-216	2257	-	-	- (aa)	-	-
ENST00000525669	PABPC4-220	582	-	-	- (aa)	-	-
ENST00000372858	PABPC4-203	2753	-	ENSP00000361949	660 (aa)	-	Q13310

Gene Model

Click here to download ENSG00000090621's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG
hsa03015	mRNA surveillance pathway	KEGG
hsa03018	RNA degradation	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000090621	Cholesterol, HDL	2.649e-005	19060910
ENSG00000090621	C-Reactive Protein	3E-15	27286809
ENSG00000090621	Cholesterol, HDL	3E-15	27286809
ENSG00000090621	Lung Volume Measurements	2E-16	28166213
ENSG00000090621	Diabetes Mellitus, Type 2	2E-9	27189021
ENSG00000090621	Cholesterol, HDL	3E-18	24097068
ENSG00000090621	Cholesterol, HDL	4E-10	20686565

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000090621	rs4660293	1	39562508	C	High density lipoprotein cholesterol levels	29615537	unit decrease	1.194	EFO_0004612
ENSG00000090621	rs4660293	1	39562508	A	C-reactive protein levels or HDL-cholesterol levels (pleiotropy)	27286809			EFO_0004458\|EFO_0004612
ENSG00000090621	rs3768321	1	39570256	T	Type 2 diabetes	27189021	[1.08-1.17]	1.13	EFO_0001360
ENSG00000090621	rs4660293	1	39562508	G	HDL cholesterol	24097068	[NR] unit decrease	0.035	EFO_0004612
ENSG00000090621	rs4660293	1	39562508	G	Diastolic blood pressure	27618448	[0.12-0.24] unit increase	0.18	EFO_0006336
ENSG00000090621	rs4660293	1	39562508	G	Mean arterial pressure	27618448	[0.19-0.41] unit increase	0.3012223	EFO_0006340
ENSG00000090621	rs3768321	1	39570256	T	Type 2 diabetes	29358691		1.118625	EFO_0001360
ENSG00000090621	rs41264487	1	39571682	?	Mean corpuscular hemoglobin	29403010	[0.02-0.043] unit decrease novel	0.0315	EFO_0004527
ENSG00000090621	rs3768321	1	39570256	T	Red cell distribution width	27863252	[0.028-0.045] unit increase	0.03667472	EFO_0005192
ENSG00000090621	rs17513135	1	39570014	T	Lung function (FEV1/FVC)	28166213	[0.028-0.048] unit decrease	0.038	EFO_0004713
ENSG00000090621	rs4660293	1	39562508	G	HDL cholesterol	20686565	[0.3-0.66] mg/dL decrease	0.48	EFO_0004612
ENSG00000090621	rs4660293	1	39562508	A	High density lipoprotein cholesterol levels	29507422	unit increase	0.035	EFO_0004612
ENSG00000090621	rs4660293	1	39562508	A	High density lipoprotein cholesterol levels	29507422	unit increase	0.037	EFO_0004612
ENSG00000090621	rs17513135	1	39570014	C	High density lipoprotein cholesterol levels	29507422	unit increase	0.037	EFO_0004612
ENSG00000090621	rs17513135	1	39570014	C	High density lipoprotein cholesterol levels	29507422	unit increase	0.039	EFO_0004612
ENSG00000090621	rs61743745	1	39571272	?	Body mass index	30595370			EFO_0004340
ENSG00000090621	rs17513135	1	39570014	?	Type 2 diabetes	30595370			EFO_0001360
ENSG00000090621	rs3768321	1	39570256	?	Red cell distribution width	30595370			EFO_0005192
ENSG00000090621	rs2293476	1	39571175	?	Lung function (FEV1/FVC)	30595370			EFO_0004713
ENSG00000090621	rs3768321	1	39570256	?	Mean corpuscular hemoglobin	30595370			EFO_0004527
ENSG00000090621	rs3768321	1	39570256	T	HDL cholesterol x physical activity interaction (2df test)	30670697			EFO_0007805\|EFO_0003940
ENSG00000090621	rs2293476	1	39571175	C	C-reactive protein levels	30388399	[0.022-0.038] unit increase	0.03	EFO_0004458
ENSG00000090621	rs2293476	1	39571175	C	C-reactive protein levels	30388399	[0.025-0.045] unit increase	0.035	EFO_0004458

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000090621's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000090621	PABPC4	73	31.111	ENSG00000159409	CELF3	69	35.714
ENSG00000090621	PABPC4	66	32.941	ENSG00000242875	RBMY1B	86	30.000
ENSG00000090621	PABPC4	62	30.328	ENSG00000076067	RBMS2	61	34.737
ENSG00000090621	PABPC4	97	33.824	ENSG00000196361	ELAVL3	92	33.735
ENSG00000090621	PABPC4	97	35.294	ENSG00000162374	ELAVL4	87	30.921
ENSG00000090621	PABPC4	97	31.356	ENSG00000078328	RBFOX1	62	35.135
ENSG00000090621	PABPC4	66	32.941	ENSG00000234414	RBMY1A1	86	30.000
ENSG00000090621	PABPC4	99	85.586	ENSG00000151846	PABPC3	99	72.671
ENSG00000090621	PABPC4	69	32.990	ENSG00000122566	HNRNPA2B1	61	33.696
ENSG00000090621	PABPC4	66	32.941	ENSG00000244395	RBMY1D	86	30.000
ENSG00000090621	PABPC4	82	32.692	ENSG00000131051	RBM39	73	38.750
ENSG00000090621	PABPC4	69	31.461	ENSG00000114503	NCBP2	64	31.818
ENSG00000090621	PABPC4	98	97.619	ENSG00000070756	PABPC1	99	100.000
ENSG00000090621	PABPC4	66	32.941	ENSG00000242389	RBMY1E	86	30.000
ENSG00000090621	PABPC4	97	36.765	ENSG00000066044	ELAVL1	81	33.065
ENSG00000090621	PABPC4	62	30.328	ENSG00000153250	RBMS1	76	34.483
ENSG00000090621	PABPC4	74	36.905	ENSG00000135486	HNRNPA1	66	34.831
ENSG00000090621	PABPC4	93	86.667	ENSG00000186288	PABPC1L2A	99	76.650
ENSG00000090621	PABPC4	62	36.986	ENSG00000161082	CELF5	66	39.130
ENSG00000090621	PABPC4	99	72.973	ENSG00000174740	PABPC5	100	64.319
ENSG00000090621	PABPC4	63	37.500	ENSG00000102317	RBM3	62	36.111
ENSG00000090621	PABPC4	99	34.783	ENSG00000151923	TIAL1	98	36.620
ENSG00000090621	PABPC4	67	32.184	ENSG00000099622	CIRBP	93	35.135
ENSG00000090621	PABPC4	61	32.911	ENSG00000161547	SRSF2	61	32.911
ENSG00000090621	PABPC4	65	32.143	ENSG00000076053	RBM7	67	34.247
ENSG00000090621	PABPC4	64	36.585	ENSG00000188529	SRSF10	59	35.714
ENSG00000090621	PABPC4	62	38.889	ENSG00000149187	CELF1	71	38.889
ENSG00000090621	PABPC4	94	30.556	ENSG00000115053	NCL	89	30.682
ENSG00000090621	PABPC4	62	35.211	ENSG00000140488	CELF6	67	38.636
ENSG00000090621	PABPC4	63	34.722	ENSG00000213516	RBMXL1	54	33.333
ENSG00000090621	PABPC4	68	34.118	ENSG00000153944	MSI2	67	34.118
ENSG00000090621	PABPC4	93	86.667	ENSG00000184388	PABPC1L2B	99	76.650
ENSG00000090621	PABPC4	100	76.744	ENSG00000254535	PABPC4L	99	75.405
ENSG00000090621	PABPC4	98	30.357	ENSG00000179950	PUF60	63	33.333
ENSG00000090621	PABPC4	97	35.294	ENSG00000107105	ELAVL2	89	34.940
ENSG00000090621	PABPC4	63	34.722	ENSG00000147274	RBMX	91	36.232
ENSG00000090621	PABPC4	63	30.952	ENSG00000144642	RBMS3	58	32.990
ENSG00000090621	PABPC4	62	35.211	ENSG00000101489	CELF4	60	31.959
ENSG00000090621	PABPC4	100	86.047	ENSG00000101104	PABPC1L	98	86.047
ENSG00000090621	PABPC4	60	40.278	ENSG00000100461	RBM23	72	40.278
ENSG00000090621	PABPC4	98	44.737	ENSG00000143368	SF3B4	75	46.237
ENSG00000090621	PABPC4	58	33.333	ENSG00000115875	SRSF7	52	35.616
ENSG00000090621	PABPC4	69	30.435	ENSG00000177733	HNRNPA0	50	31.788
ENSG00000090621	PABPC4	62	37.500	ENSG00000048740	CELF2	61	37.500
ENSG00000090621	PABPC4	94	34.314	ENSG00000116001	TIA1	88	35.766

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000090621	PABPC4	99	96.396	ENSAPOG00000001161	pabpc4	100	84.848	Acanthochromis_polyacanthus
ENSG00000090621	PABPC4	96	65.741	ENSAMEG00000015083	-	99	57.235	Ailuropoda_melanoleuca
ENSG00000090621	PABPC4	100	99.225	ENSAMEG00000011535	-	100	98.939	Ailuropoda_melanoleuca
ENSG00000090621	PABPC4	99	96.396	ENSACIG00000023343	pabpc4	100	84.810	Amphilophus_citrinellus
ENSG00000090621	PABPC4	99	96.396	ENSAOCG00000021529	pabpc4	100	90.583	Amphiprion_ocellaris
ENSG00000090621	PABPC4	99	96.396	ENSAPEG00000019196	pabpc4	100	85.008	Amphiprion_percula
ENSG00000090621	PABPC4	99	96.396	ENSATEG00000007402	pabpc4	100	84.713	Anabas_testudineus
ENSG00000090621	PABPC4	99	98.198	ENSAPLG00000009729	-	100	91.429	Anas_platyrhynchos
ENSG00000090621	PABPC4	98	100.000	ENSACAG00000002544	PABPC4	100	90.161	Anolis_carolinensis
ENSG00000090621	PABPC4	100	100.000	ENSANAG00000025079	PABPC4	100	99.848	Aotus_nancymaae
ENSG00000090621	PABPC4	99	96.396	ENSACLG00000019558	pabpc4	100	84.873	Astatotilapia_calliptera
ENSG00000090621	PABPC4	99	97.297	ENSAMXG00000018779	pabpc4	99	79.556	Astyanax_mexicanus
ENSG00000090621	PABPC4	100	100.000	ENSBTAG00000017125	PABPC4	100	98.915	Bos_taurus
ENSG00000090621	PABPC4	99	93.694	ENSBTAG00000048536	-	98	86.826	Bos_taurus
ENSG00000090621	PABPC4	86	87.727	ENSCJAG00000045953	-	92	90.123	Callithrix_jacchus
ENSG00000090621	PABPC4	100	100.000	ENSCJAG00000002512	-	100	99.697	Callithrix_jacchus
ENSG00000090621	PABPC4	100	100.000	ENSCAFG00000003081	PABPC4	100	99.208	Canis_familiaris
ENSG00000090621	PABPC4	100	100.000	ENSCAFG00020004161	PABPC4	100	99.091	Canis_lupus_dingo
ENSG00000090621	PABPC4	99	87.387	ENSCHIG00000023385	-	100	78.416	Capra_hircus
ENSG00000090621	PABPC4	100	100.000	ENSCHIG00000019398	-	100	98.939	Capra_hircus
ENSG00000090621	PABPC4	100	100.000	ENSTSYG00000006532	PABPC4	100	99.394	Carlito_syrichta
ENSG00000090621	PABPC4	99	100.000	ENSCAPG00000015984	PABPC4	100	99.392	Cavia_aperea
ENSG00000090621	PABPC4	100	100.000	ENSCPOG00000009552	PABPC4	100	99.394	Cavia_porcellus
ENSG00000090621	PABPC4	100	100.000	ENSCCAG00000037306	PABPC4	100	99.848	Cebus_capucinus
ENSG00000090621	PABPC4	100	100.000	ENSCATG00000042164	PABPC4	100	99.848	Cercocebus_atys
ENSG00000090621	PABPC4	100	100.000	ENSCLAG00000011899	PABPC4	100	99.091	Chinchilla_lanigera
ENSG00000090621	PABPC4	100	100.000	ENSCSAG00000001135	PABPC4	100	99.848	Chlorocebus_sabaeus
ENSG00000090621	PABPC4	99	99.029	ENSCHOG00000005327	PABPC4	81	97.361	Choloepus_hoffmanni
ENSG00000090621	PABPC4	100	98.450	ENSCPBG00000001038	PABPC4	100	91.746	Chrysemys_picta_bellii
ENSG00000090621	PABPC4	99	100.000	ENSCANG00000034177	PABPC4	100	99.693	Colobus_angolensis_palliatus
ENSG00000090621	PABPC4	100	100.000	ENSCGRG00001018166	Pabpc4	100	97.289	Cricetulus_griseus_chok1gshd
ENSG00000090621	PABPC4	99	100.000	ENSCGRG00000009777	Pabpc4	100	97.183	Cricetulus_griseus_crigri
ENSG00000090621	PABPC4	99	96.396	ENSCSEG00000000130	pabpc4	100	84.395	Cynoglossus_semilaevis
ENSG00000090621	PABPC4	99	96.396	ENSCVAG00000019246	pabpc4	100	85.413	Cyprinodon_variegatus
ENSG00000090621	PABPC4	99	97.297	ENSDARG00000059259	pabpc4	100	85.691	Danio_rerio
ENSG00000090621	PABPC4	99	100.000	ENSDNOG00000018444	-	100	99.464	Dasypus_novemcinctus
ENSG00000090621	PABPC4	99	71.642	ENSDNOG00000042887	-	100	68.817	Dasypus_novemcinctus
ENSG00000090621	PABPC4	97	77.273	ENSDNOG00000046918	-	100	65.079	Dasypus_novemcinctus
ENSG00000090621	PABPC4	100	100.000	ENSDORG00000011581	Pabpc4	100	99.379	Dipodomys_ordii
ENSG00000090621	PABPC4	100	100.000	ENSETEG00000018453	-	84	100.000	Echinops_telfairi
ENSG00000090621	PABPC4	98	70.800	ENSETEG00000009172	-	99	65.201	Echinops_telfairi
ENSG00000090621	PABPC4	99	96.396	ENSEBUG00000000992	pabpc4	99	80.346	Eptatretus_burgeri
ENSG00000090621	PABPC4	100	95.349	ENSEBUG00000013782	pabpc4	99	76.108	Eptatretus_burgeri
ENSG00000090621	PABPC4	100	100.000	ENSEASG00005014119	PABPC4	100	99.545	Equus_asinus_asinus
ENSG00000090621	PABPC4	100	100.000	ENSECAG00000009396	PABPC4	100	99.545	Equus_caballus
ENSG00000090621	PABPC4	100	100.000	ENSEEUG00000002962	PABPC4	100	96.212	Erinaceus_europaeus
ENSG00000090621	PABPC4	99	94.595	ENSELUG00000003195	pabpc4	99	83.201	Esox_lucius
ENSG00000090621	PABPC4	100	100.000	ENSFCAG00000015254	-	100	99.242	Felis_catus
ENSG00000090621	PABPC4	100	97.674	ENSFALG00000000543	PABPC4	100	90.952	Ficedula_albicollis
ENSG00000090621	PABPC4	96	72.093	ENSFDAG00000010581	-	100	63.361	Fukomys_damarensis
ENSG00000090621	PABPC4	100	100.000	ENSFDAG00000020016	-	100	99.394	Fukomys_damarensis
ENSG00000090621	PABPC4	99	96.396	ENSFHEG00000007548	pabpc4	99	87.123	Fundulus_heteroclitus
ENSG00000090621	PABPC4	99	96.396	ENSGMOG00000019025	pabpc4	99	83.438	Gadus_morhua
ENSG00000090621	PABPC4	100	97.674	ENSGALG00000003800	PABPC4	100	91.746	Gallus_gallus
ENSG00000090621	PABPC4	98	98.077	ENSGAFG00000018195	pabpc4	98	95.556	Gambusia_affinis
ENSG00000090621	PABPC4	99	96.396	ENSGACG00000007179	pabpc4	100	83.439	Gasterosteus_aculeatus
ENSG00000090621	PABPC4	100	97.674	ENSGAGG00000001888	PABPC4	100	91.587	Gopherus_agassizii
ENSG00000090621	PABPC4	100	100.000	ENSGGOG00000004002	PABPC4	100	100.000	Gorilla_gorilla
ENSG00000090621	PABPC4	99	98.507	ENSGGOG00000039139	-	91	85.354	Gorilla_gorilla
ENSG00000090621	PABPC4	99	96.396	ENSHBUG00000020206	pabpc4	100	85.032	Haplochromis_burtoni
ENSG00000090621	PABPC4	100	100.000	ENSHGLG00000011162	PABPC4	100	99.545	Heterocephalus_glaber_female
ENSG00000090621	PABPC4	100	100.000	ENSHGLG00100001580	PABPC4	100	99.534	Heterocephalus_glaber_male
ENSG00000090621	PABPC4	99	96.396	ENSHCOG00000012694	pabpc4	100	84.211	Hippocampus_comes
ENSG00000090621	PABPC4	100	96.899	ENSIPUG00000016620	pabpc4	99	83.176	Ictalurus_punctatus
ENSG00000090621	PABPC4	100	100.000	ENSSTOG00000010416	PABPC4	100	99.379	Ictidomys_tridecemlineatus
ENSG00000090621	PABPC4	100	100.000	ENSJJAG00000007781	Pabpc4	100	97.050	Jaculus_jaculus
ENSG00000090621	PABPC4	99	96.396	ENSKMAG00000013597	pabpc4	99	85.072	Kryptolebias_marmoratus
ENSG00000090621	PABPC4	99	96.396	ENSLBEG00000013654	pabpc4	100	83.651	Labrus_bergylta
ENSG00000090621	PABPC4	100	97.674	ENSLACG00000011907	PABPC4	100	88.013	Latimeria_chalumnae
ENSG00000090621	PABPC4	99	98.198	ENSLOCG00000001877	pabpc4	99	86.142	Lepisosteus_oculatus
ENSG00000090621	PABPC4	100	100.000	ENSLAFG00000000151	PABPC4	100	99.187	Loxodonta_africana
ENSG00000090621	PABPC4	100	100.000	ENSMFAG00000041481	PABPC4	100	99.848	Macaca_fascicularis
ENSG00000090621	PABPC4	100	100.000	ENSMMUG00000007497	PABPC4	100	99.848	Macaca_mulatta
ENSG00000090621	PABPC4	100	100.000	ENSMNEG00000043054	PABPC4	100	99.697	Macaca_nemestrina
ENSG00000090621	PABPC4	100	100.000	ENSMLEG00000040716	PABPC4	100	99.848	Mandrillus_leucophaeus
ENSG00000090621	PABPC4	99	96.396	ENSMAMG00000010025	pabpc4	99	84.776	Mastacembelus_armatus
ENSG00000090621	PABPC4	99	96.396	ENSMZEG00005006141	pabpc4	100	84.713	Maylandia_zebra
ENSG00000090621	PABPC4	98	100.000	ENSMGAG00000005408	PABPC4	100	87.905	Meleagris_gallopavo
ENSG00000090621	PABPC4	99	97.500	ENSMAUG00000019763	-	84	95.413	Mesocricetus_auratus
ENSG00000090621	PABPC4	99	82.883	ENSMAUG00000004089	-	92	81.287	Mesocricetus_auratus
ENSG00000090621	PABPC4	74	89.423	ENSMAUG00000001295	-	97	89.423	Mesocricetus_auratus
ENSG00000090621	PABPC4	99	91.304	ENSMICG00000036729	-	100	85.740	Microcebus_murinus
ENSG00000090621	PABPC4	100	100.000	ENSMICG00000016633	-	100	99.267	Microcebus_murinus
ENSG00000090621	PABPC4	100	100.000	ENSMOCG00000006763	Pabpc4	100	97.741	Microtus_ochrogaster
ENSG00000090621	PABPC4	99	96.396	ENSMMOG00000002363	pabpc4	99	81.359	Mola_mola
ENSG00000090621	PABPC4	99	81.513	ENSMODG00000018051	-	91	73.729	Monodelphis_domestica
ENSG00000090621	PABPC4	99	38.261	ENSMODG00000019847	-	68	82.692	Monodelphis_domestica
ENSG00000090621	PABPC4	100	99.225	ENSMODG00000017657	-	100	88.788	Monodelphis_domestica
ENSG00000090621	PABPC4	99	96.396	ENSMALG00000011017	pabpc4	100	84.286	Monopterus_albus
ENSG00000090621	PABPC4	99	100.000	MGP_CAROLIEiJ_G0026435	-	100	100.000	Mus_caroli
ENSG00000090621	PABPC4	98	100.000	MGP_CAROLIEiJ_G0024864	-	100	84.696	Mus_caroli
ENSG00000090621	PABPC4	100	99.225	ENSMUSG00000011257	Pabpc4	100	99.405	Mus_musculus
ENSG00000090621	PABPC4	99	100.000	MGP_PahariEiJ_G0028765	Pabpc4	100	100.000	Mus_pahari
ENSG00000090621	PABPC4	99	99.099	MGP_SPRETEiJ_G0027415	Pabpc4	100	100.000	Mus_spretus
ENSG00000090621	PABPC4	100	100.000	ENSMPUG00000014414	-	100	99.242	Mustela_putorius_furo
ENSG00000090621	PABPC4	99	60.360	ENSMPUG00000006836	-	100	53.477	Mustela_putorius_furo
ENSG00000090621	PABPC4	100	100.000	ENSMLUG00000012068	PABPC4	100	99.187	Myotis_lucifugus
ENSG00000090621	PABPC4	100	100.000	ENSNGAG00000018292	Pabpc4	100	99.224	Nannospalax_galili
ENSG00000090621	PABPC4	99	96.396	ENSNBRG00000009708	pabpc4	97	96.667	Neolamprologus_brichardi
ENSG00000090621	PABPC4	56	92.105	ENSNBRG00000009692	-	95	60.145	Neolamprologus_brichardi
ENSG00000090621	PABPC4	69	86.441	ENSNBRG00000010047	-	75	86.441	Neolamprologus_brichardi
ENSG00000090621	PABPC4	100	100.000	ENSNLEG00000011928	PABPC4	100	99.845	Nomascus_leucogenys
ENSG00000090621	PABPC4	100	100.000	ENSOPRG00000011984	PABPC4	87	98.737	Ochotona_princeps
ENSG00000090621	PABPC4	99	97.015	ENSODEG00000017434	-	100	89.206	Octodon_degus
ENSG00000090621	PABPC4	99	83.784	ENSODEG00000013457	-	86	100.000	Octodon_degus
ENSG00000090621	PABPC4	100	100.000	ENSODEG00000006592	-	100	98.485	Octodon_degus
ENSG00000090621	PABPC4	97	80.423	ENSODEG00000013825	-	100	83.478	Octodon_degus
ENSG00000090621	PABPC4	99	96.396	ENSONIG00000008176	pabpc4	100	85.032	Oreochromis_niloticus
ENSG00000090621	PABPC4	99	98.198	ENSOANG00000010001	PABPC4	100	91.270	Ornithorhynchus_anatinus
ENSG00000090621	PABPC4	100	100.000	ENSOCUG00000000562	PABPC4	88	99.209	Oryctolagus_cuniculus
ENSG00000090621	PABPC4	99	98.000	ENSORLG00000017479	pabpc4	99	90.741	Oryzias_latipes
ENSG00000090621	PABPC4	99	98.000	ENSORLG00020018644	pabpc4	99	90.741	Oryzias_latipes_hni
ENSG00000090621	PABPC4	99	98.000	ENSORLG00015015042	pabpc4	99	90.741	Oryzias_latipes_hsok
ENSG00000090621	PABPC4	99	96.396	ENSOMEG00000014410	pabpc4	99	85.096	Oryzias_melastigma
ENSG00000090621	PABPC4	100	100.000	ENSOGAG00000004067	PABPC4	100	99.227	Otolemur_garnettii
ENSG00000090621	PABPC4	100	100.000	ENSOARG00000020060	PABPC4	100	98.939	Ovis_aries
ENSG00000090621	PABPC4	100	100.000	ENSPPAG00000043625	PABPC4	100	100.000	Pan_paniscus
ENSG00000090621	PABPC4	100	100.000	ENSPPRG00000024727	PABPC4	100	99.242	Panthera_pardus
ENSG00000090621	PABPC4	100	100.000	ENSPTIG00000005829	PABPC4	100	99.242	Panthera_tigris_altaica
ENSG00000090621	PABPC4	100	100.000	ENSPTRG00000000573	PABPC4	100	100.000	Pan_troglodytes
ENSG00000090621	PABPC4	100	100.000	ENSPANG00000009484	PABPC4	100	99.697	Papio_anubis
ENSG00000090621	PABPC4	99	97.297	ENSPKIG00000025356	pabpc4	99	85.443	Paramormyrops_kingsleyae
ENSG00000090621	PABPC4	100	98.450	ENSPSIG00000016892	PABPC4	100	91.746	Pelodiscus_sinensis
ENSG00000090621	PABPC4	99	96.396	ENSPMGG00000009073	pabpc4	99	82.419	Periophthalmus_magnuspinnatus
ENSG00000090621	PABPC4	100	100.000	ENSPEMG00000023569	-	99	97.273	Peromyscus_maniculatus_bairdii
ENSG00000090621	PABPC4	99	99.099	ENSPEMG00000024193	-	99	93.323	Peromyscus_maniculatus_bairdii
ENSG00000090621	PABPC4	99	96.429	ENSPMAG00000007885	pabpc4	100	73.265	Petromyzon_marinus
ENSG00000090621	PABPC4	100	95.349	ENSPMAG00000002836	pabpc4	100	73.601	Petromyzon_marinus
ENSG00000090621	PABPC4	100	99.225	ENSPCIG00000020674	PABPC4	100	93.571	Phascolarctos_cinereus
ENSG00000090621	PABPC4	100	94.574	ENSPFOG00000002682	pabpc4	100	85.008	Poecilia_formosa
ENSG00000090621	PABPC4	100	94.574	ENSPLAG00000010112	pabpc4	100	84.848	Poecilia_latipinna
ENSG00000090621	PABPC4	100	94.574	ENSPMEG00000019739	pabpc4	100	85.167	Poecilia_mexicana
ENSG00000090621	PABPC4	98	97.015	ENSPREG00000001589	pabpc4	100	84.848	Poecilia_reticulata
ENSG00000090621	PABPC4	100	100.000	ENSPPYG00000001506	PABPC4	100	100.000	Pongo_abelii
ENSG00000090621	PABPC4	100	100.000	ENSPCAG00000003341	PABPC4	100	94.242	Procavia_capensis
ENSG00000090621	PABPC4	99	95.522	ENSPCOG00000025882	-	95	94.059	Propithecus_coquereli
ENSG00000090621	PABPC4	100	100.000	ENSPCOG00000023725	-	100	99.546	Propithecus_coquereli
ENSG00000090621	PABPC4	99	100.000	ENSPVAG00000002187	PABPC4	100	98.655	Pteropus_vampyrus
ENSG00000090621	PABPC4	99	96.396	ENSPNYG00000006134	pabpc4	100	84.873	Pundamilia_nyererei
ENSG00000090621	PABPC4	99	96.396	ENSPNAG00000024355	pabpc4	100	84.494	Pygocentrus_nattereri
ENSG00000090621	PABPC4	100	100.000	ENSRNOG00000015642	Pabpc4	100	97.981	Rattus_norvegicus
ENSG00000090621	PABPC4	99	98.507	ENSRNOG00000028592	AABR07035074.1	100	95.807	Rattus_norvegicus
ENSG00000090621	PABPC4	100	100.000	ENSRBIG00000039761	PABPC4	100	99.848	Rhinopithecus_bieti
ENSG00000090621	PABPC4	100	100.000	ENSRROG00000033355	PABPC4	100	99.848	Rhinopithecus_roxellana
ENSG00000090621	PABPC4	100	100.000	ENSSBOG00000026193	PABPC4	100	99.697	Saimiri_boliviensis_boliviensis
ENSG00000090621	PABPC4	100	99.225	ENSSHAG00000018139	PABPC4	100	92.063	Sarcophilus_harrisii
ENSG00000090621	PABPC4	98	99.038	ENSSFOG00015023514	pabpc4	99	85.714	Scleropages_formosus
ENSG00000090621	PABPC4	99	96.396	ENSSMAG00000009007	pabpc4	99	84.677	Scophthalmus_maximus
ENSG00000090621	PABPC4	99	96.396	ENSSDUG00000012683	pabpc4	100	84.395	Seriola_dumerili
ENSG00000090621	PABPC4	99	96.396	ENSSLDG00000013025	pabpc4	100	84.395	Seriola_lalandi_dorsalis
ENSG00000090621	PABPC4	99	100.000	ENSSARG00000000310	PABPC4	100	91.970	Sorex_araneus
ENSG00000090621	PABPC4	100	97.674	ENSSPUG00000003204	PABPC4	100	90.385	Sphenodon_punctatus
ENSG00000090621	PABPC4	99	96.396	ENSSPAG00000009252	pabpc4	98	89.625	Stegastes_partitus
ENSG00000090621	PABPC4	99	53.731	ENSSSCG00000036170	-	96	51.730	Sus_scrofa
ENSG00000090621	PABPC4	100	100.000	ENSSSCG00000003660	-	100	99.091	Sus_scrofa
ENSG00000090621	PABPC4	100	97.674	ENSTGUG00000001266	PABPC4	100	87.595	Taeniopygia_guttata
ENSG00000090621	PABPC4	99	96.396	ENSTRUG00000005907	pabpc4	99	84.135	Takifugu_rubripes
ENSG00000090621	PABPC4	99	96.396	ENSTNIG00000016902	pabpc4	99	79.516	Tetraodon_nigroviridis
ENSG00000090621	PABPC4	99	100.000	ENSTBEG00000009035	PABPC4	100	88.571	Tupaia_belangeri
ENSG00000090621	PABPC4	99	100.000	ENSTTRG00000014340	PABPC4	100	87.059	Tursiops_truncatus
ENSG00000090621	PABPC4	100	100.000	ENSUAMG00000000303	PABPC4	100	99.049	Ursus_americanus
ENSG00000090621	PABPC4	100	100.000	ENSUMAG00000019585	PABPC4	100	99.057	Ursus_maritimus
ENSG00000090621	PABPC4	98	100.000	ENSVPAG00000010041	PABPC4	77	97.872	Vicugna_pacos
ENSG00000090621	PABPC4	100	100.000	ENSVVUG00000005215	PABPC4	100	99.208	Vulpes_vulpes
ENSG00000090621	PABPC4	100	85.271	ENSXETG00000010946	pabpc4	100	83.333	Xenopus_tropicalis
ENSG00000090621	PABPC4	100	97.674	ENSXETG00000027221	-	100	97.024	Xenopus_tropicalis
ENSG00000090621	PABPC4	98	98.462	ENSXCOG00000013190	pabpc4	96	89.623	Xiphophorus_couchianus
ENSG00000090621	PABPC4	100	94.574	ENSXMAG00000019007	pabpc4	100	84.689	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003730	mRNA 3'-UTR binding	21873635.	IBA	Function
GO:0005515	protein binding	11369516.27871484.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	21940797.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	8524242.21940797.	IDA	Component
GO:0005829	cytosol	21873635.	IBA	Component
GO:0005829	cytosol	-	IDA	Component
GO:0006396	RNA processing	8524242.	TAS	Process
GO:0006401	RNA catabolic process	8524242.	TAS	Process
GO:0006412	translation	8524242.	TAS	Process
GO:0007596	blood coagulation	9030741.	TAS	Process
GO:0008143	poly(A) binding	21873635.	IBA	Function
GO:0008143	poly(A) binding	8524242.	IDA	Function
GO:0008266	poly(U) RNA binding	21873635.	IBA	Function
GO:0008266	poly(U) RNA binding	8524242.	IDA	Function
GO:0010494	cytoplasmic stress granule	21873635.	IBA	Component
GO:0010494	cytoplasmic stress granule	21940797.	IDA	Component
GO:0017130	poly(C) RNA binding	8524242.	IDA	Function
GO:0043488	regulation of mRNA stability	-	IEA	Process
GO:0061515	myeloid cell development	-	IEA	Process
GO:1990904	ribonucleoprotein complex	21873635.	IBA	Component
GO:1990904	ribonucleoprotein complex	17289661.	IDA	Component