EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000090905 (Gene tree)
Gene ID: 27327
Gene Symbol: TNRC6A
Alias: CAGH26|KIAA1460|GW182|TNRC6
Full Name: trinucleotide repeat containing adaptor 6A
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 217,424 bases
Position: chr16:24,610,209-24,827,632
Accession: 11969
RBP type: canonical RBP
Summary: This gene encodes a member of the trinucleotide repeat containing 6 protein family. The protein functions in post-transcriptional gene silencing through the RNA interference (RNAi) and microRNA pathways. The protein associates with messenger RNAs and Argonaute proteins in cytoplasmic bodies known as GW-bodies or P-bodies. Inhibiting expression of this gene delocalizes other GW-body proteins and impairs RNAi and microRNA-induced gene silencing. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000379144	Ago_hook	PF10427.9	1.2e-18	1	1
ENSP00000326900	Ago_hook	PF10427.9	1.3e-18	1	1
ENSP00000404278	Ago_hook	PF10427.9	1e-07	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
31037644	Viral Regulation of RNA Granules in Infected Cells.	Virol Sin	2019 Apr	Zhang Q	doi: 10.1007/s12250-019-00122-3
29726904	RNA-binding Protein Trinucleotide repeat-containing 6A Regulates the Formation of Circular RNA 0006916, with Important Functions in Lung Cancer Cells.	Carcinogenesis	2018 May 3	Dai X	doi: 10.1093/carcin/bgy061
16284622	Disruption of GW bodies impairs mammalian RNA interference.	Nat Cell Biol	2005 Dec	Jakymiw A	-
16177138	A crucial role for GW182 and the DCP1:DCP2 decapping complex in miRNA-mediated gene silencing.	RNA	2005 Nov	Rehwinkel J	-
14598044	Clinical and serological associations of autoantibodies to GW bodies and a novel cytoplasmic autoantigen GW182.	J Mol Med (Berl)	2003 Dec	Eystathioy T	-
17938239	Reiterated WG/GW motifs form functionally and evolutionarily conserved ARGONAUTE-binding platforms in RNAi-related components.	Genes Dev	2007 Oct 15	El-Shami M	-
20976148	The microRNA and messengerRNA profile of the RNA-induced silencing complex in human primary astrocyte and astrocytoma cells.	PLoS One	2010 Oct 18	Moser JJ	doi: 10.1371/journal.pone.0013445.
23535175	Role of Rck-Pat1b binding in assembly of processing-bodies.	RNA Biol	2013 Apr	Ozgur S	doi: 10.4161/rna.24086
29080206	Structural Dynamics of the GW182 Silencing Domain Including its RNA Recognition motif (RRM) Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry.	J Am Soc Mass Spectrom	2018 Jan	Cieplak-Rotowska MK	doi: 10.1007/s13361-017-1830-9
30997501	TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.	Nucleic Acids Res	2019 Jul 9	Li Y	doi: 10.1093/nar/gkz278.
31324450	Multidomain Convergence of Argonaute during RISC Assembly Correlates with the Formation of Internal Water Clusters.	Mol Cell	2019 Jun 27	Park MS	doi: 10.1016/j.molcel.2019.06.011

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000568903	TNRC6A-215	943	-	-	- (aa)	-	-
ENST00000477487	TNRC6A-206	2740	-	-	- (aa)	-	-
ENST00000569376	TNRC6A-217	610	-	ENSP00000459297	96 (aa)	-	I3L218
ENST00000568750	TNRC6A-213	609	-	ENSP00000457273	203 (aa)	-	H3BTQ1
ENST00000563201	TNRC6A-210	276	-	-	- (aa)	-	-
ENST00000395799	TNRC6A-202	8438	XM_017023144	ENSP00000379144	1962 (aa)	XP_016878633	Q8NDV7
ENST00000569098	TNRC6A-216	587	-	ENSP00000456394	160 (aa)	-	H3BRT3
ENST00000462400	TNRC6A-204	2550	-	-	- (aa)	-	-
ENST00000450465	TNRC6A-203	3700	XM_005255257	ENSP00000404278	906 (aa)	XP_005255314	H7C269
ENST00000464539	TNRC6A-205	1853	-	-	- (aa)	-	-
ENST00000561726	TNRC6A-208	543	-	-	- (aa)	-	-
ENST00000491718	TNRC6A-207	7956	-	ENSP00000460688	40 (aa)	-	I3L3S5
ENST00000567232	TNRC6A-212	523	-	-	- (aa)	-	-
ENST00000562829	TNRC6A-209	277	-	-	- (aa)	-	-
ENST00000568806	TNRC6A-214	298	-	-	- (aa)	-	-
ENST00000566108	TNRC6A-211	454	-	-	- (aa)	-	-
ENST00000315183	TNRC6A-201	8303	XM_017023150	ENSP00000326900	1913 (aa)	XP_016878639	Q8NDV7
ENST00000569634	TNRC6A-218	552	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000090905's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000090905	Diabetes Mellitus, Type 2	5E-6	23386860

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000090905	rs8045064	16	24664268	?	Alzheimer's disease (cognitive decline)	23535033	unit decrease	0.21	EFO_0000249
ENSG00000090905	rs17177078	16	24799360	?	Type 2 diabetes (dietary heme iron intake interaction)	23386860	[NR] unit increase	0.83	EFO_0001360\|EFO_0008355
ENSG00000090905	rs11639856	16	24777324	A	Systolic blood pressure	27618448	[0.22-0.46] unit decrease	0.34	EFO_0006335
ENSG00000090905	rs11639856	16	24777324	A	Pulse pressure	27618448	[0.15-0.31] unit decrease	0.23	EFO_0005763
ENSG00000090905	rs34172651	16	24755520	T	Intelligence (MTAG)	29326435	[0.014-0.027] unit decrease	0.0205231	EFO_0004337
ENSG00000090905	rs7188873	16	24715743	A	Intelligence (MTAG)	29326435	[0.013-0.025] unit increase	0.01899372	EFO_0004337
ENSG00000090905	rs1862451	16	24792299	A	Cognitive performance	30038396	[0.014-0.026] unit decrease	0.0202	EFO_0008354
ENSG00000090905	rs28512462	16	24700485	C	Educational attainment (MTAG)	30038396	[0.009-0.014] unit increase	0.0115	EFO_0004784
ENSG00000090905	rs77989568	16	24680327	C	Self-reported math ability (MTAG)	30038396	[0.008-0.0162] unit decrease	0.0121	EFO_0004875
ENSG00000090905	rs28512462	16	24700485	C	Highest math class taken (MTAG)	30038396	[0.0074-0.014] unit increase	0.0107	EFO_0004875
ENSG00000090905	rs1862451	16	24792299	A	Cognitive performance (MTAG)	30038396	[0.013-0.023] unit decrease	0.0177	EFO_0008354
ENSG00000090905	rs7202252	16	24730365	T	Experiencing mood swings	29500382	z score decrease	5.46	EFO_0008475
ENSG00000090905	rs34172651	16	24755520	T	General cognitive ability	29844566	z-score decrease	6.059	EFO_0004337
ENSG00000090905	rs34172651	16	24755520	T	Intelligence	29942086	z-score decrease	7.122	EFO_0004337
ENSG00000090905	rs72768642	16	24699893	T	Intelligence	29942086	z-score decrease	5.667	EFO_0004337
ENSG00000090905	rs7188873	16	24715743	A	Intelligence	29942086	z-score increase	5.605	EFO_0004337
ENSG00000090905	rs28512462	16	24700485	C	Educational attainment (years of education)	30038396	[0.0085-0.0139] unit increase	0.0112	EFO_0004784
ENSG00000090905	rs7188873	16	24715743	?	Educational attainment (years of education)	30595370			EFO_0004784
ENSG00000090905	rs112927956	16	24712680	?	Menarche (age at onset)	30595370			EFO_0004703
ENSG00000090905	rs7204281	16	24773154	?	Body mass index	30595370			EFO_0004340
ENSG00000090905	rs12708665	16	24716906	?	Macular thickness	30535121	[0.27-0.57] unit decrease	0.422	EFO_0008375
ENSG00000090905	rs7188873	16	24715743	A	Educational attainment (years of education)	30038396	[0.0082-0.0136] unit increase	0.0109	EFO_0004784
ENSG00000090905	rs72768626	16	24681727	A	Alcohol consumption (drinks per week)	30643258	[0.021-0.04] unit increase	0.030120945	EFO_0007878
ENSG00000090905	rs2188717	16	24718909	?	Systolic blood pressure	30595370			EFO_0006335
ENSG00000090905	rs7188873	16	24715743	?	Smoking status	30595370			EFO_0006527
ENSG00000090905	rs12930481	16	24764117	G	Age of smoking initiation (MTAG)	30643251	[0.0075-0.014] unit increase	0.0107512	EFO_0005670
ENSG00000090905	rs17177078	16	24799360	T	Alcohol consumption (drinks per week) (MTAG)	30643251	[0.017-0.027] unit decrease	0.0220624	EFO_0007878
ENSG00000090905	rs12708665	16	24716906	G	Smoking cessation (MTAG)	30643251	[0.0071-0.0138] unit increase	0.0104373	EFO_0004319
ENSG00000090905	rs200534	16	24741320	G	Pulse pressure	30578418	[0.12-0.23] mmHg increase	0.1758	EFO_0005763
ENSG00000090905	rs2188717	16	24718909	T	Systolic blood pressure	30578418	[0.24-0.42] mmHg decrease	0.3316	EFO_0006335
ENSG00000090905	rs200541	16	24721820	A	Systolic blood pressure	27841878	unit decrease	0.281	EFO_0006335
ENSG00000090905	rs200541	16	24721820	A	Pulse pressure	27841878	unit decrease	0.175	EFO_0005763
ENSG00000090905	rs7188873	16	24715743	G	Smoking initiation (ever regular vs never regular) (MTAG)	30643251	[0.0076-0.012] unit increase	0.00979102	EFO_0006527
ENSG00000090905	rs7188873	16	24715743	G	Smoking initiation (ever regular vs never regular)	30643251	[0.015-0.025] unit increase	0.020295778	EFO_0006527
ENSG00000090905	rs17177078	16	24799360	T	Alcohol consumption (drinks per week)	30643251	[0.016-0.028] unit decrease	0.02231549	EFO_0007878
ENSG00000090905	rs200528	16	24747810	?	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy)	30940143			EFO_0004325\|EFO_0000341

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000090905's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000090905	TNRC6A	99	65.000	ENSG00000078687	TNRC6C	98	44.295
ENSG00000090905	TNRC6A	100	50.617	ENSG00000100354	TNRC6B	94	45.399

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000090905	TNRC6A	98	96.554	ENSAMEG00000009333	TNRC6A	100	96.554	Ailuropoda_melanoleuca
ENSG00000090905	TNRC6A	100	92.547	ENSAPLG00000009978	TNRC6A	100	81.927	Anas_platyrhynchos
ENSG00000090905	TNRC6A	99	74.419	ENSACAG00000011857	TNRC6A	100	56.496	Anolis_carolinensis
ENSG00000090905	TNRC6A	100	98.675	ENSANAG00000025252	TNRC6A	100	98.675	Aotus_nancymaae
ENSG00000090905	TNRC6A	98	87.931	ENSAMXG00000019919	tnrc6a	99	56.818	Astyanax_mexicanus
ENSG00000090905	TNRC6A	100	95.452	ENSBTAG00000017999	TNRC6A	100	95.086	Bos_taurus
ENSG00000090905	TNRC6A	100	98.780	ENSCJAG00000020677	TNRC6A	100	98.780	Callithrix_jacchus
ENSG00000090905	TNRC6A	99	96.585	ENSCAFG00000017531	TNRC6A	100	96.585	Canis_familiaris
ENSG00000090905	TNRC6A	98	94.488	ENSCAFG00020021160	TNRC6A	99	95.079	Canis_lupus_dingo
ENSG00000090905	TNRC6A	100	95.034	ENSCHIG00000019448	TNRC6A	100	95.224	Capra_hircus
ENSG00000090905	TNRC6A	100	96.840	ENSTSYG00000012711	TNRC6A	100	96.840	Carlito_syrichta
ENSG00000090905	TNRC6A	99	96.128	ENSCPOG00000036684	TNRC6A	100	96.128	Cavia_porcellus
ENSG00000090905	TNRC6A	100	98.981	ENSCCAG00000033664	TNRC6A	100	98.981	Cebus_capucinus
ENSG00000090905	TNRC6A	99	98.896	ENSCATG00000019284	TNRC6A	99	98.896	Cercocebus_atys
ENSG00000090905	TNRC6A	100	92.002	ENSCLAG00000010217	TNRC6A	100	91.898	Chinchilla_lanigera
ENSG00000090905	TNRC6A	100	99.185	ENSCSAG00000006561	TNRC6A	100	99.185	Chlorocebus_sabaeus
ENSG00000090905	TNRC6A	100	95.000	ENSCHOG00000009374	TNRC6A	95	91.627	Choloepus_hoffmanni
ENSG00000090905	TNRC6A	100	92.500	ENSCPBG00000001881	TNRC6A	99	82.390	Chrysemys_picta_bellii
ENSG00000090905	TNRC6A	100	99.032	ENSCANG00000041549	TNRC6A	100	99.032	Colobus_angolensis_palliatus
ENSG00000090905	TNRC6A	100	94.723	ENSCGRG00001015021	Tnrc6a	100	94.619	Cricetulus_griseus_chok1gshd
ENSG00000090905	TNRC6A	100	94.375	ENSCGRG00000013351	Tnrc6a	99	93.410	Cricetulus_griseus_crigri
ENSG00000090905	TNRC6A	100	79.375	ENSDARG00000079688	tnrc6a	99	57.015	Danio_rerio
ENSG00000090905	TNRC6A	100	93.168	ENSDNOG00000013989	TNRC6A	99	93.538	Dasypus_novemcinctus
ENSG00000090905	TNRC6A	94	97.351	ENSETEG00000014658	TNRC6A	99	85.371	Echinops_telfairi
ENSG00000090905	TNRC6A	100	96.587	ENSEASG00005017693	TNRC6A	100	96.944	Equus_asinus_asinus
ENSG00000090905	TNRC6A	100	96.587	ENSECAG00000025056	TNRC6A	100	96.944	Equus_caballus
ENSG00000090905	TNRC6A	98	89.504	ENSEEUG00000004530	TNRC6A	99	89.504	Erinaceus_europaeus
ENSG00000090905	TNRC6A	100	95.107	ENSFCAG00000025236	TNRC6A	100	94.954	Felis_catus
ENSG00000090905	TNRC6A	100	92.547	ENSFALG00000003757	TNRC6A	99	79.829	Ficedula_albicollis
ENSG00000090905	TNRC6A	100	92.547	ENSGALG00000006068	TNRC6A	99	82.767	Gallus_gallus
ENSG00000090905	TNRC6A	100	92.547	ENSGAGG00000023209	TNRC6A	99	81.886	Gopherus_agassizii
ENSG00000090905	TNRC6A	99	99.384	ENSGGOG00000005137	TNRC6A	99	99.384	Gorilla_gorilla
ENSG00000090905	TNRC6A	100	72.466	ENSHGLG00000007368	-	99	71.996	Heterocephalus_glaber_female
ENSG00000090905	TNRC6A	99	94.022	ENSHGLG00000012474	-	100	93.970	Heterocephalus_glaber_female
ENSG00000090905	TNRC6A	99	93.498	ENSHGLG00100012496	-	100	93.445	Heterocephalus_glaber_male
ENSG00000090905	TNRC6A	99	96.589	ENSSTOG00000023394	TNRC6A	99	96.589	Ictidomys_tridecemlineatus
ENSG00000090905	TNRC6A	100	83.125	ENSLACG00000006277	TNRC6A	100	70.258	Latimeria_chalumnae
ENSG00000090905	TNRC6A	100	85.625	ENSLOCG00000005517	tnrc6a	93	83.223	Lepisosteus_oculatus
ENSG00000090905	TNRC6A	100	94.375	ENSLAFG00000004209	TNRC6A	99	94.641	Loxodonta_africana
ENSG00000090905	TNRC6A	100	95.000	ENSMFAG00000003824	TNRC6A	99	97.815	Macaca_fascicularis
ENSG00000090905	TNRC6A	100	98.930	ENSMMUG00000020428	TNRC6A	100	98.930	Macaca_mulatta
ENSG00000090905	TNRC6A	100	98.882	ENSMNEG00000034854	TNRC6A	100	98.882	Macaca_nemestrina
ENSG00000090905	TNRC6A	100	95.113	ENSMLEG00000042737	TNRC6A	99	95.113	Mandrillus_leucophaeus
ENSG00000090905	TNRC6A	100	92.547	ENSMGAG00000006455	TNRC6A	99	80.586	Meleagris_gallopavo
ENSG00000090905	TNRC6A	100	94.410	ENSMAUG00000012750	Tnrc6a	100	94.410	Mesocricetus_auratus
ENSG00000090905	TNRC6A	100	97.910	ENSMICG00000030685	TNRC6A	100	97.910	Microcebus_murinus
ENSG00000090905	TNRC6A	100	94.929	ENSMOCG00000000152	Tnrc6a	100	94.668	Microtus_ochrogaster
ENSG00000090905	TNRC6A	100	81.183	ENSMODG00000016348	TNRC6A	99	81.805	Monodelphis_domestica
ENSG00000090905	TNRC6A	100	95.000	MGP_CAROLIEiJ_G0030425	Tnrc6a	100	94.639	Mus_caroli
ENSG00000090905	TNRC6A	100	95.000	ENSMUSG00000052707	Tnrc6a	99	94.996	Mus_musculus
ENSG00000090905	TNRC6A	100	95.000	MGP_PahariEiJ_G0013635	Tnrc6a	100	95.282	Mus_pahari
ENSG00000090905	TNRC6A	100	95.000	MGP_SPRETEiJ_G0031539	Tnrc6a	100	94.996	Mus_spretus
ENSG00000090905	TNRC6A	100	94.375	ENSMPUG00000012324	TNRC6A	100	83.959	Mustela_putorius_furo
ENSG00000090905	TNRC6A	100	95.000	ENSMLUG00000002701	TNRC6A	100	92.662	Myotis_lucifugus
ENSG00000090905	TNRC6A	99	95.659	ENSNGAG00000020702	Tnrc6a	100	95.607	Nannospalax_galili
ENSG00000090905	TNRC6A	98	96.968	ENSNLEG00000011851	TNRC6A	99	96.968	Nomascus_leucogenys
ENSG00000090905	TNRC6A	100	93.750	ENSMEUG00000015959	-	77	89.480	Notamacropus_eugenii
ENSG00000090905	TNRC6A	96	99.254	ENSOPRG00000005819	TNRC6A	96	99.254	Ochotona_princeps
ENSG00000090905	TNRC6A	100	93.125	ENSODEG00000012802	TNRC6A	99	89.610	Octodon_degus
ENSG00000090905	TNRC6A	100	93.750	ENSOANG00000007672	TNRC6A	99	83.139	Ornithorhynchus_anatinus
ENSG00000090905	TNRC6A	100	93.168	ENSOCUG00000004325	TNRC6A	100	92.981	Oryctolagus_cuniculus
ENSG00000090905	TNRC6A	99	97.072	ENSOGAG00000006666	TNRC6A	100	97.072	Otolemur_garnettii
ENSG00000090905	TNRC6A	100	94.375	ENSOARG00000017950	TNRC6A	98	95.981	Ovis_aries
ENSG00000090905	TNRC6A	99	99.542	ENSPPAG00000028379	TNRC6A	100	99.542	Pan_paniscus
ENSG00000090905	TNRC6A	100	95.107	ENSPPRG00000005861	TNRC6A	100	94.954	Panthera_pardus
ENSG00000090905	TNRC6A	100	95.000	ENSPTIG00000006346	TNRC6A	99	94.595	Panthera_tigris_altaica
ENSG00000090905	TNRC6A	99	97.852	ENSPTRG00000007898	TNRC6A	99	97.852	Pan_troglodytes
ENSG00000090905	TNRC6A	100	96.743	ENSPANG00000018523	TNRC6A	100	96.743	Papio_anubis
ENSG00000090905	TNRC6A	100	80.625	ENSPKIG00000012859	tnrc6a	96	79.459	Paramormyrops_kingsleyae
ENSG00000090905	TNRC6A	100	92.547	ENSPSIG00000003965	TNRC6A	100	77.635	Pelodiscus_sinensis
ENSG00000090905	TNRC6A	100	95.000	ENSPEMG00000016318	Tnrc6a	100	94.505	Peromyscus_maniculatus_bairdii
ENSG00000090905	TNRC6A	100	93.750	ENSPCIG00000012106	TNRC6A	100	83.708	Phascolarctos_cinereus
ENSG00000090905	TNRC6A	99	98.981	ENSPPYG00000007202	TNRC6A	100	98.981	Pongo_abelii
ENSG00000090905	TNRC6A	95	100.000	ENSPCAG00000008260	TNRC6A	94	100.000	Procavia_capensis
ENSG00000090905	TNRC6A	100	95.668	ENSPCOG00000010134	TNRC6A	100	95.668	Propithecus_coquereli
ENSG00000090905	TNRC6A	89	71.126	ENSPVAG00000012066	TNRC6A	99	70.955	Pteropus_vampyrus
ENSG00000090905	TNRC6A	100	95.000	ENSRNOG00000024737	Tnrc6a	100	94.314	Rattus_norvegicus
ENSG00000090905	TNRC6A	99	99.018	ENSRBIG00000014222	TNRC6A	100	99.018	Rhinopithecus_bieti
ENSG00000090905	TNRC6A	100	98.879	ENSRROG00000032360	TNRC6A	100	98.879	Rhinopithecus_roxellana
ENSG00000090905	TNRC6A	98	97.755	ENSSBOG00000036197	TNRC6A	100	99.356	Saimiri_boliviensis_boliviensis
ENSG00000090905	TNRC6A	100	82.947	ENSSHAG00000008811	TNRC6A	99	84.160	Sarcophilus_harrisii
ENSG00000090905	TNRC6A	100	84.375	ENSSFOG00015008920	tnrc6a	99	63.759	Scleropages_formosus
ENSG00000090905	TNRC6A	99	77.434	ENSSARG00000002479	TNRC6A	89	83.333	Sorex_araneus
ENSG00000090905	TNRC6A	100	90.000	ENSSPUG00000010525	TNRC6A	100	78.835	Sphenodon_punctatus
ENSG00000090905	TNRC6A	100	98.675	ENSSSCG00000038870	TNRC6A	100	97.659	Sus_scrofa
ENSG00000090905	TNRC6A	100	93.125	ENSTGUG00000006142	TNRC6A	100	80.135	Taeniopygia_guttata
ENSG00000090905	TNRC6A	100	93.125	ENSTBEG00000014965	TNRC6A	100	94.575	Tupaia_belangeri
ENSG00000090905	TNRC6A	100	95.000	ENSTTRG00000002008	TNRC6A	93	98.058	Tursiops_truncatus
ENSG00000090905	TNRC6A	90	97.222	ENSUAMG00000006656	-	93	95.687	Ursus_americanus
ENSG00000090905	TNRC6A	99	98.564	ENSUMAG00000008274	TNRC6A	100	97.349	Ursus_maritimus
ENSG00000090905	TNRC6A	90	94.444	ENSVPAG00000010764	-	57	85.493	Vicugna_pacos
ENSG00000090905	TNRC6A	99	96.608	ENSVVUG00000005380	TNRC6A	100	96.591	Vulpes_vulpes
ENSG00000090905	TNRC6A	100	84.375	ENSXETG00000030437	TNRC6A	99	65.965	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000932	P-body	21873635.	IBA	Component
GO:0000932	P-body	20616046.	IDA	Component
GO:0003723	RNA binding	22681889.	HDA	Function
GO:0005515	protein binding	19167051.19324964.19383768.19716330.21063388.21840310.21981923.22484317.23090477.24768540.25416956.26134560.28546213.28877994.	IPI	Function
GO:0005654	nucleoplasm	21873635.	IBA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005794	Golgi apparatus	-	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0007223	Wnt signaling pathway, calcium modulating pathway	-	TAS	Process
GO:0009267	cellular response to starvation	-	IEA	Process
GO:0010628	positive regulation of gene expression	-	TAS	Process
GO:0010629	negative regulation of gene expression	-	TAS	Process
GO:0035068	micro-ribonucleoprotein complex	21873635.	IBA	Component
GO:0035068	micro-ribonucleoprotein complex	17671087.	IDA	Component
GO:0035194	posttranscriptional gene silencing by RNA	-	TAS	Process
GO:0035195	gene silencing by miRNA	21873635.	IBA	Process
GO:0035195	gene silencing by miRNA	23172285.	IMP	Process
GO:0035278	miRNA mediated inhibition of translation	17671087.	IDA	Process
GO:0043231	intracellular membrane-bounded organelle	-	IDA	Component
GO:0045652	regulation of megakaryocyte differentiation	-	TAS	Process
GO:0060213	positive regulation of nuclear-transcribed mRNA poly(A) tail shortening	21873635.	IBA	Process
GO:0060964	regulation of gene silencing by miRNA	-	TAS	Process