EuRBPDB

Description

Ensembl ID: ENSG00000092148 (Gene tree)
Gene ID: 25831
Gene Symbol: HECTD1
Alias: KIAA1131
Full Name: HECT domain E3 ubiquitin protein ligase 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 107,949 bases
Position: chr14:31,100,112-31,208,060
Accession: 20157
RBP type: non-canonical RBP
Summary: (HECT Domain E3 Ubiquitin Protein Ligase 1) is a Protein Coding gene. Among its related pathways are Class I MHC mediated antigen processing and presentation and Innate Immune System. Gene Ontology (GO) annotations related to this gene include binding and ubiquitin-protein transferase activity. An important paralog of this gene is TRIP12.

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000399332	HECTD1-201	9134	XM_011536622	ENSP00000382269	2610 (aa)	XP_011534924	Q9ULT8
ENST00000557369	HECTD1-217	554	-	ENSP00000452233	185 (aa)	-	H0YJV8
ENST00000554471	HECTD1-206	819	-	ENSP00000479695	212 (aa)	-	A0A087WVU6
ENST00000556474	HECTD1-215	1046	-	-	- (aa)	-	-
ENST00000555311	HECTD1-209	503	-	-	- (aa)	-	-
ENST00000556281	HECTD1-214	684	-	-	- (aa)	-	-
ENST00000557321	HECTD1-216	571	-	-	- (aa)	-	-
ENST00000553700	HECTD1-203	9080	XM_005267502	ENSP00000450697	2610 (aa)	XP_005267559	Q9ULT8
ENST00000554850	HECTD1-207	382	-	-	- (aa)	-	-
ENST00000611816	HECTD1-219	8980	-	ENSP00000484981	2614 (aa)	-	A0A087X2H1
ENST00000556004	HECTD1-212	595	-	-	- (aa)	-	-
ENST00000556224	HECTD1-213	3267	-	ENSP00000452015	926 (aa)	-	G3V4V5
ENST00000554027	HECTD1-205	556	-	-	- (aa)	-	-
ENST00000555843	HECTD1-210	4281	-	-	- (aa)	-	-
ENST00000553616	HECTD1-202	570	-	-	- (aa)	-	-
ENST00000553957	HECTD1-204	4395	-	ENSP00000451860	1465 (aa)	-	H0YJP0
ENST00000557695	HECTD1-218	524	-	-	- (aa)	-	-
ENST00000555915	HECTD1-211	775	-	ENSP00000450920	122 (aa)	-	H0YJ72
ENST00000554882	HECTD1-208	3748	-	ENSP00000451260	976 (aa)	-	H0YJD4

Gene Model

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Orthologs identified by RBPome

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000092148	HECTD1	100	99.028	ENSMUSG00000035247	Hectd1	100	98.927	Mus_musculus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003170	heart valve development	-	ISS	Process
GO:0003281	ventricular septum development	-	ISS	Process
GO:0004842	ubiquitin-protein transferase activity	-	IEA	Function
GO:0005515	protein binding	12421765.	IPI	Function
GO:0035904	aorta development	-	ISS	Process
GO:0046872	metal ion binding	-	IEA	Function
GO:0070534	protein K63-linked ubiquitination	21873635.	IBA	Process