EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000092978 (Gene tree)
Gene ID: 55105
Gene Symbol: GPATCH2
Alias: FLJ10252|CT110|PPP1R30|Pfa1|GPATC2
Full Name: G-patch domain containing 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 204,111 bases
Position: chr1:217,426,992-217,631,102
Accession: 25499
RBP type: canonical RBP
Summary: The gene encodes a nuclear factor that may play a role in spermatogenesis and in tumor growth during breast cancer. The encoded protein contains a G-patch domain with an RNA binding motif. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000355902	G-patch	PF01585.23	8e-15	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000485274	GPATCH2-204	343	-	-	- (aa)	-	-
ENST00000470014	GPATCH2-203	442	-	-	- (aa)	-	-
ENST00000489246	GPATCH2-205	715	-	-	- (aa)	-	-
ENST00000366934	GPATCH2-201	3218	XM_011509694	ENSP00000355901	376 (aa)	XP_011507996	Q9NW75
ENST00000366935	GPATCH2-202	5851	XM_011509689	ENSP00000355902	528 (aa)	XP_011507991	Q9NW75

Gene Model

Click here to download ENSG00000092978's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000092978	Heart Failure	2.4571534E-004	-
ENSG00000092978	beta Carotene	2.2750000E-005	-
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	5.2440000E-006	22837378
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	3.1240000E-006	22837378
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	3.2440000E-006	22837378
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	4.2730000E-006	22837378
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	4.9130000E-006	22837378
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	5.1880000E-006	22837378
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	5.1600000E-006	22837378
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	3.1960000E-006	22837378
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	3.3710000E-006	22837378
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	5.2230000E-006	22837378
ENSG00000092978	Pulmonary Disease, Chronic Obstructive	4.8750000E-006	22837378
ENSG00000092978	Adipose Tissue	6E-6	22589738
ENSG00000092978	Body Mass Index	6E-6	22589738
ENSG00000092978	Heart Rate	1E-11	27798624

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000092978	rs11454451	1	217549549	CT	Resting heart rate	27798624	[0.18-0.33] unit increase	0.2558	EFO_0004351
ENSG00000092978	rs2059397	1	217544790	G	Visceral adipose tissue adjusted for BMI	22589738			EFO_0004765\|EFO_0004340
ENSG00000092978	rs76358930	1	217588949	T	Familial lung cancer	29924316	[1.84-4.60]	2.91	EFO_0001071\|EFO_0006953
ENSG00000092978	rs12408022	1	217545447	T	Diastolic blood pressure	28135244	[0.14-0.26] unit increase	0.198	EFO_0006336
ENSG00000092978	rs7533141	1	217543535	?	Proliferative diabetic retinopathy (vs NPDR and no DR)	30487263	[NR]	1.47	EFO_0009322
ENSG00000092978	rs17046596	1	217549107	A	Diastolic blood pressure	27841878	unit decrease	0.151	EFO_0006336

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000092978's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000092978	GPATCH2	100	94.508	ENSAMEG00000000532	GPATCH2	100	94.508	Ailuropoda_melanoleuca
ENSG00000092978	GPATCH2	97	50.364	ENSACIG00000017628	si:ch73-21k16.4	99	52.269	Amphilophus_citrinellus
ENSG00000092978	GPATCH2	92	50.000	ENSAOCG00000020838	si:ch73-21k16.4	99	50.000	Amphiprion_ocellaris
ENSG00000092978	GPATCH2	97	52.865	ENSAPEG00000007324	si:ch73-21k16.4	99	53.974	Amphiprion_percula
ENSG00000092978	GPATCH2	83	72.816	ENSATEG00000003701	si:ch73-21k16.4	99	72.816	Anabas_testudineus
ENSG00000092978	GPATCH2	93	77.846	ENSAPLG00000005559	GPATCH2	99	77.846	Anas_platyrhynchos
ENSG00000092978	GPATCH2	97	74.755	ENSACAG00000014945	GPATCH2	95	74.755	Anolis_carolinensis
ENSG00000092978	GPATCH2	100	96.970	ENSANAG00000032851	GPATCH2	100	96.970	Aotus_nancymaae
ENSG00000092978	GPATCH2	97	53.663	ENSACLG00000008706	si:ch73-21k16.4	99	55.210	Astatotilapia_calliptera
ENSG00000092978	GPATCH2	97	54.802	ENSAMXG00000001662	si:ch73-21k16.4	99	55.932	Astyanax_mexicanus
ENSG00000092978	GPATCH2	100	93.762	ENSBTAG00000001574	GPATCH2	100	93.762	Bos_taurus
ENSG00000092978	GPATCH2	100	97.727	ENSCJAG00000047537	GPATCH2	91	97.727	Callithrix_jacchus
ENSG00000092978	GPATCH2	100	94.508	ENSCAFG00000010781	GPATCH2	100	94.508	Canis_familiaris
ENSG00000092978	GPATCH2	100	93.384	ENSCHIG00000018042	GPATCH2	100	93.384	Capra_hircus
ENSG00000092978	GPATCH2	96	89.567	ENSCAPG00000007843	GPATCH2	99	89.567	Cavia_aperea
ENSG00000092978	GPATCH2	98	91.826	ENSCPOG00000003966	GPATCH2	99	89.943	Cavia_porcellus
ENSG00000092978	GPATCH2	100	98.295	ENSCCAG00000010195	GPATCH2	100	98.295	Cebus_capucinus
ENSG00000092978	GPATCH2	99	97.849	ENSCATG00000038238	GPATCH2	100	94.508	Cercocebus_atys
ENSG00000092978	GPATCH2	98	91.008	ENSCLAG00000009274	GPATCH2	99	89.943	Chinchilla_lanigera
ENSG00000092978	GPATCH2	97	77.495	ENSCPBG00000013037	GPATCH2	99	77.495	Chrysemys_picta_bellii
ENSG00000092978	GPATCH2	100	98.106	ENSCANG00000031261	GPATCH2	100	98.106	Colobus_angolensis_palliatus
ENSG00000092978	GPATCH2	96	88.409	ENSCGRG00001024577	Gpatch2	99	87.856	Cricetulus_griseus_chok1gshd
ENSG00000092978	GPATCH2	96	88.409	ENSCGRG00000015039	Gpatch2	99	88.409	Cricetulus_griseus_crigri
ENSG00000092978	GPATCH2	97	53.028	ENSCSEG00000002545	si:ch73-21k16.4	99	54.312	Cynoglossus_semilaevis
ENSG00000092978	GPATCH2	94	53.096	ENSCVAG00000006306	si:ch73-21k16.4	98	54.597	Cyprinodon_variegatus
ENSG00000092978	GPATCH2	97	54.406	ENSDARG00000101260	GPATCH2	99	55.747	Danio_rerio
ENSG00000092978	GPATCH2	54	92.308	ENSDNOG00000000826	GPATCH2	100	92.308	Dasypus_novemcinctus
ENSG00000092978	GPATCH2	98	93.767	ENSDORG00000030155	Gpatch2	100	93.517	Dipodomys_ordii
ENSG00000092978	GPATCH2	99	87.452	ENSETEG00000012316	GPATCH2	99	87.452	Echinops_telfairi
ENSG00000092978	GPATCH2	75	42.092	ENSEBUG00000014275	si:ch73-21k16.4	99	40.678	Eptatretus_burgeri
ENSG00000092978	GPATCH2	100	93.750	ENSEASG00005003507	GPATCH2	100	93.750	Equus_asinus_asinus
ENSG00000092978	GPATCH2	100	93.750	ENSECAG00000013263	GPATCH2	100	93.750	Equus_caballus
ENSG00000092978	GPATCH2	96	84.540	ENSEEUG00000008748	GPATCH2	99	85.127	Erinaceus_europaeus
ENSG00000092978	GPATCH2	97	55.701	ENSELUG00000004934	si:ch73-21k16.4	99	55.701	Esox_lucius
ENSG00000092978	GPATCH2	100	94.886	ENSFCAG00000007129	GPATCH2	99	94.886	Felis_catus
ENSG00000092978	GPATCH2	97	76.367	ENSFALG00000012223	GPATCH2	99	76.367	Ficedula_albicollis
ENSG00000092978	GPATCH2	95	87.873	ENSFDAG00000011026	GPATCH2	99	87.873	Fukomys_damarensis
ENSG00000092978	GPATCH2	97	45.265	ENSFHEG00000008699	si:ch73-21k16.4	89	58.621	Fundulus_heteroclitus
ENSG00000092978	GPATCH2	82	55.882	ENSGMOG00000001595	si:ch73-21k16.4	81	61.029	Gadus_morhua
ENSG00000092978	GPATCH2	98	76.152	ENSGALG00000009627	GPATCH2	99	76.712	Gallus_gallus
ENSG00000092978	GPATCH2	94	52.820	ENSGAFG00000005041	si:ch73-21k16.4	97	53.947	Gambusia_affinis
ENSG00000092978	GPATCH2	97	54.991	ENSGACG00000013427	si:ch73-21k16.4	100	56.121	Gasterosteus_aculeatus
ENSG00000092978	GPATCH2	97	78.474	ENSGAGG00000013122	GPATCH2	99	78.474	Gopherus_agassizii
ENSG00000092978	GPATCH2	100	99.621	ENSGGOG00000009440	GPATCH2	100	99.621	Gorilla_gorilla
ENSG00000092978	GPATCH2	97	53.663	ENSHBUG00000014399	si:ch73-21k16.4	99	55.210	Haplochromis_burtoni
ENSG00000092978	GPATCH2	98	92.098	ENSHGLG00000019513	GPATCH2	99	90.892	Heterocephalus_glaber_female
ENSG00000092978	GPATCH2	98	92.098	ENSHGLG00100003689	GPATCH2	99	90.892	Heterocephalus_glaber_male
ENSG00000092978	GPATCH2	93	56.354	ENSHCOG00000011331	si:ch73-21k16.4	99	51.533	Hippocampus_comes
ENSG00000092978	GPATCH2	97	41.300	ENSIPUG00000012840	si:ch73-21k16.4	99	41.923	Ictalurus_punctatus
ENSG00000092978	GPATCH2	100	95.076	ENSSTOG00000024959	GPATCH2	100	95.076	Ictidomys_tridecemlineatus
ENSG00000092978	GPATCH2	94	90.935	ENSJJAG00000019244	Gpatch2	97	85.631	Jaculus_jaculus
ENSG00000092978	GPATCH2	97	53.565	ENSLBEG00000008187	si:ch73-21k16.4	99	54.662	Labrus_bergylta
ENSG00000092978	GPATCH2	97	73.777	ENSLACG00000013951	GPATCH2	99	73.777	Latimeria_chalumnae
ENSG00000092978	GPATCH2	97	63.353	ENSLOCG00000016058	si:ch73-21k16.4	99	63.353	Lepisosteus_oculatus
ENSG00000092978	GPATCH2	96	91.913	ENSLAFG00000003787	GPATCH2	99	91.913	Loxodonta_africana
ENSG00000092978	GPATCH2	100	98.674	ENSMFAG00000000617	GPATCH2	100	98.674	Macaca_fascicularis
ENSG00000092978	GPATCH2	100	98.674	ENSMMUG00000014946	GPATCH2	100	98.674	Macaca_mulatta
ENSG00000092978	GPATCH2	100	98.674	ENSMNEG00000034969	GPATCH2	100	98.674	Macaca_nemestrina
ENSG00000092978	GPATCH2	100	98.674	ENSMLEG00000032285	GPATCH2	100	98.674	Mandrillus_leucophaeus
ENSG00000092978	GPATCH2	97	52.930	ENSMAMG00000015684	si:ch73-21k16.4	99	54.113	Mastacembelus_armatus
ENSG00000092978	GPATCH2	97	53.663	ENSMZEG00005015040	si:ch73-21k16.4	99	55.210	Maylandia_zebra
ENSG00000092978	GPATCH2	61	75.232	ENSMGAG00000009428	GPATCH2	99	75.232	Meleagris_gallopavo
ENSG00000092978	GPATCH2	100	87.689	ENSMAUG00000004851	Gpatch2	100	87.689	Mesocricetus_auratus
ENSG00000092978	GPATCH2	100	96.402	ENSMICG00000037090	GPATCH2	100	96.402	Microcebus_murinus
ENSG00000092978	GPATCH2	94	90.141	ENSMOCG00000020821	Gpatch2	99	88.447	Microtus_ochrogaster
ENSG00000092978	GPATCH2	97	52.852	ENSMMOG00000015329	si:ch73-21k16.4	99	53.745	Mola_mola
ENSG00000092978	GPATCH2	97	82.192	ENSMODG00000004195	GPATCH2	96	80.798	Monodelphis_domestica
ENSG00000092978	GPATCH2	97	51.188	ENSMALG00000016801	si:ch73-21k16.4	99	51.554	Monopterus_albus
ENSG00000092978	GPATCH2	100	84.470	MGP_CAROLIEiJ_G0015030	Gpatch2	100	84.921	Mus_caroli
ENSG00000092978	GPATCH2	100	84.470	ENSMUSG00000039210	Gpatch2	100	84.921	Mus_musculus
ENSG00000092978	GPATCH2	100	85.606	MGP_PahariEiJ_G0028262	Gpatch2	100	86.111	Mus_pahari
ENSG00000092978	GPATCH2	100	84.659	MGP_SPRETEiJ_G0015830	Gpatch2	100	85.119	Mus_spretus
ENSG00000092978	GPATCH2	100	95.076	ENSMPUG00000004269	GPATCH2	100	95.076	Mustela_putorius_furo
ENSG00000092978	GPATCH2	99	86.828	ENSNGAG00000002207	Gpatch2	99	84.221	Nannospalax_galili
ENSG00000092978	GPATCH2	97	51.111	ENSNBRG00000020932	si:ch73-21k16.4	99	52.593	Neolamprologus_brichardi
ENSG00000092978	GPATCH2	100	99.432	ENSNLEG00000014201	GPATCH2	100	99.432	Nomascus_leucogenys
ENSG00000092978	GPATCH2	93	81.948	ENSMEUG00000012239	GPATCH2	99	74.067	Notamacropus_eugenii
ENSG00000092978	GPATCH2	100	88.826	ENSOPRG00000010126	GPATCH2	100	88.826	Ochotona_princeps
ENSG00000092978	GPATCH2	98	88.828	ENSODEG00000014927	GPATCH2	99	86.528	Octodon_degus
ENSG00000092978	GPATCH2	97	55.159	ENSONIG00000000570	si:ch73-21k16.4	100	56.742	Oreochromis_niloticus
ENSG00000092978	GPATCH2	92	79.480	ENSOANG00000008549	GPATCH2	99	75.047	Ornithorhynchus_anatinus
ENSG00000092978	GPATCH2	100	93.371	ENSOCUG00000014512	GPATCH2	100	93.371	Oryctolagus_cuniculus
ENSG00000092978	GPATCH2	97	53.102	ENSORLG00000016810	si:ch73-21k16.4	99	54.380	Oryzias_latipes
ENSG00000092978	GPATCH2	97	53.199	ENSORLG00020003127	si:ch73-21k16.4	99	54.479	Oryzias_latipes_hni
ENSG00000092978	GPATCH2	97	52.920	ENSORLG00015022304	si:ch73-21k16.4	99	54.197	Oryzias_latipes_hsok
ENSG00000092978	GPATCH2	97	52.930	ENSOMEG00000017809	si:ch73-21k16.4	99	52.930	Oryzias_melastigma
ENSG00000092978	GPATCH2	100	95.076	ENSOGAG00000004485	GPATCH2	100	95.076	Otolemur_garnettii
ENSG00000092978	GPATCH2	100	93.384	ENSOARG00000011440	GPATCH2	100	93.384	Ovis_aries
ENSG00000092978	GPATCH2	100	99.621	ENSPPAG00000038887	GPATCH2	100	99.621	Pan_paniscus
ENSG00000092978	GPATCH2	100	95.076	ENSPPRG00000013363	GPATCH2	99	95.076	Panthera_pardus
ENSG00000092978	GPATCH2	100	99.621	ENSPTRG00000001986	GPATCH2	100	99.621	Pan_troglodytes
ENSG00000092978	GPATCH2	100	98.674	ENSPANG00000020943	GPATCH2	100	98.674	Papio_anubis
ENSG00000092978	GPATCH2	97	58.869	ENSPKIG00000004245	si:ch73-21k16.4	99	58.674	Paramormyrops_kingsleyae
ENSG00000092978	GPATCH2	97	77.495	ENSPSIG00000005373	GPATCH2	99	77.495	Pelodiscus_sinensis
ENSG00000092978	GPATCH2	97	50.092	ENSPMGG00000000611	si:ch73-21k16.4	99	50.929	Periophthalmus_magnuspinnatus
ENSG00000092978	GPATCH2	96	89.587	ENSPEMG00000018364	Gpatch2	98	89.587	Peromyscus_maniculatus_bairdii
ENSG00000092978	GPATCH2	100	81.285	ENSPCIG00000027888	GPATCH2	100	81.285	Phascolarctos_cinereus
ENSG00000092978	GPATCH2	97	52.834	ENSPFOG00000008062	si:ch73-21k16.4	99	54.098	Poecilia_formosa
ENSG00000092978	GPATCH2	97	52.834	ENSPLAG00000022219	si:ch73-21k16.4	99	54.098	Poecilia_latipinna
ENSG00000092978	GPATCH2	97	52.834	ENSPMEG00000010687	si:ch73-21k16.4	99	54.286	Poecilia_mexicana
ENSG00000092978	GPATCH2	99	49.631	ENSPREG00000011915	si:ch73-21k16.4	99	52.641	Poecilia_reticulata
ENSG00000092978	GPATCH2	98	99.455	ENSPPYG00000000216	GPATCH2	100	93.371	Pongo_abelii
ENSG00000092978	GPATCH2	93	80.857	ENSPCAG00000013998	GPATCH2	100	74.037	Procavia_capensis
ENSG00000092978	GPATCH2	98	91.129	ENSPVAG00000010649	GPATCH2	99	90.038	Pteropus_vampyrus
ENSG00000092978	GPATCH2	97	53.663	ENSPNYG00000014144	si:ch73-21k16.4	99	55.210	Pundamilia_nyererei
ENSG00000092978	GPATCH2	100	98.106	ENSRROG00000012833	GPATCH2	100	98.106	Rhinopithecus_roxellana
ENSG00000092978	GPATCH2	100	97.348	ENSSBOG00000028891	GPATCH2	100	97.348	Saimiri_boliviensis_boliviensis
ENSG00000092978	GPATCH2	91	81.739	ENSSHAG00000015123	GPATCH2	98	75.800	Sarcophilus_harrisii
ENSG00000092978	GPATCH2	94	60.080	ENSSFOG00015000674	gpatch2	97	59.363	Scleropages_formosus
ENSG00000092978	GPATCH2	97	52.190	ENSSMAG00000009585	si:ch73-21k16.4	99	53.467	Scophthalmus_maximus
ENSG00000092978	GPATCH2	97	53.114	ENSSDUG00000011998	si:ch73-21k16.4	99	54.396	Seriola_dumerili
ENSG00000092978	GPATCH2	97	53.297	ENSSLDG00000025385	si:ch73-21k16.4	99	54.579	Seriola_lalandi_dorsalis
ENSG00000092978	GPATCH2	96	88.605	ENSSARG00000013063	GPATCH2	100	88.605	Sorex_araneus
ENSG00000092978	GPATCH2	97	53.297	ENSSPAG00000023569	si:ch73-21k16.4	99	54.662	Stegastes_partitus
ENSG00000092978	GPATCH2	100	91.682	ENSSSCG00000027207	GPATCH2	100	91.682	Sus_scrofa
ENSG00000092978	GPATCH2	97	56.182	ENSTRUG00000015569	si:ch73-21k16.4	99	56.000	Takifugu_rubripes
ENSG00000092978	GPATCH2	93	56.513	ENSTNIG00000016304	si:ch73-21k16.4	96	55.766	Tetraodon_nigroviridis
ENSG00000092978	GPATCH2	60	100.000	ENSTBEG00000012337	-	62	100.000	Tupaia_belangeri
ENSG00000092978	GPATCH2	83	100.000	ENSTTRG00000003739	GPATCH2	83	100.000	Tursiops_truncatus
ENSG00000092978	GPATCH2	100	94.886	ENSUMAG00000020588	GPATCH2	100	94.886	Ursus_maritimus
ENSG00000092978	GPATCH2	98	92.412	ENSVPAG00000005192	GPATCH2	100	89.036	Vicugna_pacos
ENSG00000092978	GPATCH2	100	94.508	ENSVVUG00000012998	GPATCH2	100	94.508	Vulpes_vulpes
ENSG00000092978	GPATCH2	98	71.346	ENSXETG00000021194	gpatch2	99	71.346	Xenopus_tropicalis
ENSG00000092978	GPATCH2	94	51.044	ENSXCOG00000007145	si:ch73-21k16.4	99	51.941	Xiphophorus_couchianus
ENSG00000092978	GPATCH2	97	52.007	ENSXMAG00000004679	si:ch73-21k16.4	99	53.091	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003676	nucleic acid binding	-	IEA	Function
GO:0005730	nucleolus	-	IEA	Component
GO:0010923	negative regulation of phosphatase activity	21873635.	IBA	Process
GO:0010923	negative regulation of phosphatase activity	19389623.	IDA	Process
GO:0016607	nuclear speck	-	IDA	Component