EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000093167 (Gene tree)
Gene ID: 9209
Gene Symbol: LRRFIP2
Alias: HUFI-2
Full Name: LRR binding FLII interacting protein 2
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 131,064 bases
Position: chr3:37,052,626-37,183,689
Accession: 6703
RBP type: canonical RBP
Summary: The protein encoded by this gene, along with MYD88, binds to the cytosolic tail of toll-like receptor 4 (TLR4), which results in activation of nuclear factor kappa B signaling. The ubiquitin-like protein FAT10 prevents the interaction of the encoded protein and TLR4, thereby inactivating the nuclear factor kappa B signaling pathway. In addition, this protein can downregulate the NLRP3 inflammasome by recruiting the caspase-1 inhibitor Flightless-I to the inflammasome complex. [provided by RefSeq, Jan 2017]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000346349	LRRFIP	PF09738.9	9e-109	1	1
ENSP00000405480	LRRFIP	PF09738.9	1.2e-104	1	1
ENSP00000416364	LRRFIP	PF09738.9	1.2e-104	1	1
ENSP00000379705	LRRFIP	PF09738.9	2.6e-97	1	3
ENSP00000379705	LRRFIP	PF09738.9	2.6e-97	2	3
ENSP00000379705	LRRFIP	PF09738.9	2.6e-97	3	3
ENSP00000338727	LRRFIP	PF09738.9	5.2e-86	1	2
ENSP00000338727	LRRFIP	PF09738.9	5.2e-86	2	2
ENSP00000409574	LRRFIP	PF09738.9	2.1e-65	1	1
ENSP00000413026	LRRFIP	PF09738.9	4.8e-44	1	1
ENSP00000412206	LRRFIP	PF09738.9	6.3e-12	1	1
ENSP00000391360	LRRFIP	PF09738.9	7.6e-11	1	1
ENSP00000416013	LRRFIP	PF09738.9	7.6e-11	1	1
ENSP00000416907	LRRFIP	PF09738.9	7.6e-11	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000436858	LRRFIP2-207	389	-	ENSP00000416013	59 (aa)	-	C9JJC9
ENST00000483306	LRRFIP2-216	755	-	-	- (aa)	-	-
ENST00000460646	LRRFIP2-212	2857	-	-	- (aa)	-	-
ENST00000482466	LRRFIP2-215	462	-	-	- (aa)	-	-
ENST00000440230	LRRFIP2-209	1989	-	ENSP00000405480	424 (aa)	-	Q9Y608
ENST00000396428	LRRFIP2-203	1791	XM_005265551	ENSP00000379705	503 (aa)	XP_005265608	Q9Y608
ENST00000496479	LRRFIP2-219	3585	-	-	- (aa)	-	-
ENST00000438374	LRRFIP2-208	560	-	ENSP00000412206	67 (aa)	-	C9J0U5
ENST00000490597	LRRFIP2-218	1044	-	-	- (aa)	-	-
ENST00000481682	LRRFIP2-214	561	-	-	- (aa)	-	-
ENST00000452742	LRRFIP2-211	352	-	ENSP00000391360	59 (aa)	-	C9J321
ENST00000487246	LRRFIP2-217	644	-	-	- (aa)	-	-
ENST00000416425	LRRFIP2-204	961	-	ENSP00000409574	225 (aa)	-	C9JSU1
ENST00000496825	LRRFIP2-220	409	NR_145514	-	- (aa)	-	-
ENST00000461672	LRRFIP2-213	563	-	-	- (aa)	-	-
ENST00000354379	LRRFIP2-202	2821	XM_024453823	ENSP00000346349	400 (aa)	XP_024309591	Q9Y608
ENST00000440742	LRRFIP2-210	545	-	ENSP00000413026	182 (aa)	-	H7C3N9
ENST00000336686	LRRFIP2-201	3208	XM_005265539	ENSP00000338727	721 (aa)	XP_005265596	Q9Y608
ENST00000434749	LRRFIP2-206	718	-	ENSP00000416907	59 (aa)	-	C9JC17
ENST00000421276	LRRFIP2-205	2522	XM_006713400	ENSP00000416364	424 (aa)	XP_006713463	Q9Y608

Gene Model

Click here to download ENSG00000093167's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000093167	Platelet Function Tests	2.6384042E-006	-
ENSG00000093167	Platelet Function Tests	1.5278800E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000093167	rs6786857	3	37163524	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000093167's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000093167	LRRFIP2	100	77.966	ENSG00000124831	LRRFIP1	99	47.606

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000093167	LRRFIP2	83	55.182	ENSAPOG00000013642	-	89	55.182	Acanthochromis_polyacanthus
ENSG00000093167	LRRFIP2	100	91.525	ENSAPOG00000020575	lrrfip2	100	91.525	Acanthochromis_polyacanthus
ENSG00000093167	LRRFIP2	99	42.466	ENSAMEG00000008474	-	95	43.030	Ailuropoda_melanoleuca
ENSG00000093167	LRRFIP2	100	98.305	ENSAMEG00000017893	LRRFIP2	100	89.598	Ailuropoda_melanoleuca
ENSG00000093167	LRRFIP2	100	89.831	ENSACIG00000004319	lrrfip2	100	89.831	Amphilophus_citrinellus
ENSG00000093167	LRRFIP2	100	76.271	ENSAOCG00000009531	lrrfip1b	100	76.271	Amphiprion_ocellaris
ENSG00000093167	LRRFIP2	100	76.271	ENSAOCG00000009212	-	95	75.410	Amphiprion_ocellaris
ENSG00000093167	LRRFIP2	100	91.525	ENSAOCG00000004334	lrrfip2	100	91.525	Amphiprion_ocellaris
ENSG00000093167	LRRFIP2	100	76.271	ENSAPEG00000007555	lrrfip1b	97	75.410	Amphiprion_percula
ENSG00000093167	LRRFIP2	100	91.667	ENSAPEG00000024638	lrrfip2	100	91.525	Amphiprion_percula
ENSG00000093167	LRRFIP2	100	76.271	ENSAPEG00000002932	-	99	55.556	Amphiprion_percula
ENSG00000093167	LRRFIP2	100	72.881	ENSATEG00000007628	-	100	52.344	Anabas_testudineus
ENSG00000093167	LRRFIP2	100	91.525	ENSATEG00000013082	lrrfip2	100	91.525	Anabas_testudineus
ENSG00000093167	LRRFIP2	100	76.271	ENSATEG00000007942	-	80	60.135	Anabas_testudineus
ENSG00000093167	LRRFIP2	96	42.857	ENSAPLG00000004640	LRRFIP1	94	45.839	Anas_platyrhynchos
ENSG00000093167	LRRFIP2	100	96.610	ENSAPLG00000010430	LRRFIP2	100	77.393	Anas_platyrhynchos
ENSG00000093167	LRRFIP2	100	94.915	ENSACAG00000009967	LRRFIP2	100	78.049	Anolis_carolinensis
ENSG00000093167	LRRFIP2	96	39.234	ENSACAG00000015939	LRRFIP1	100	42.341	Anolis_carolinensis
ENSG00000093167	LRRFIP2	100	100.000	ENSANAG00000020666	LRRFIP2	100	99.057	Aotus_nancymaae
ENSG00000093167	LRRFIP2	99	42.326	ENSANAG00000021311	LRRFIP1	93	41.468	Aotus_nancymaae
ENSG00000093167	LRRFIP2	100	76.271	ENSACLG00000001232	-	99	58.163	Astatotilapia_calliptera
ENSG00000093167	LRRFIP2	96	73.438	ENSACLG00000014982	-	100	50.758	Astatotilapia_calliptera
ENSG00000093167	LRRFIP2	100	90.000	ENSACLG00000021229	lrrfip2	99	89.831	Astatotilapia_calliptera
ENSG00000093167	LRRFIP2	100	93.220	ENSAMXG00000003561	lrrfip2	100	82.609	Astyanax_mexicanus
ENSG00000093167	LRRFIP2	100	45.902	ENSAMXG00000013471	lrrfip1b	100	46.409	Astyanax_mexicanus
ENSG00000093167	LRRFIP2	100	71.186	ENSAMXG00000035379	lrrfip1a	99	51.982	Astyanax_mexicanus
ENSG00000093167	LRRFIP2	100	98.305	ENSBTAG00000016760	LRRFIP2	100	97.000	Bos_taurus
ENSG00000093167	LRRFIP2	100	77.966	ENSBTAG00000005354	LRRFIP1	99	48.271	Bos_taurus
ENSG00000093167	LRRFIP2	96	48.438	WBGene00018998	flap-1	98	30.250	Caenorhabditis_elegans
ENSG00000093167	LRRFIP2	100	97.000	ENSCJAG00000042879	-	100	97.000	Callithrix_jacchus
ENSG00000093167	LRRFIP2	100	98.795	ENSCJAG00000012550	-	100	97.217	Callithrix_jacchus
ENSG00000093167	LRRFIP2	100	77.966	ENSCJAG00000000491	LRRFIP1	90	57.618	Callithrix_jacchus
ENSG00000093167	LRRFIP2	100	98.507	ENSCAFG00000004793	LRRFIP2	100	94.632	Canis_familiaris
ENSG00000093167	LRRFIP2	99	42.466	ENSCAFG00000012303	-	96	44.296	Canis_familiaris
ENSG00000093167	LRRFIP2	100	98.667	ENSCAFG00020001365	LRRFIP2	100	96.698	Canis_lupus_dingo
ENSG00000093167	LRRFIP2	100	74.576	ENSCAFG00020024621	LRRFIP1	99	54.255	Canis_lupus_dingo
ENSG00000093167	LRRFIP2	100	99.398	ENSCHIG00000021299	LRRFIP2	100	96.934	Capra_hircus
ENSG00000093167	LRRFIP2	88	58.192	ENSCHIG00000006587	-	90	58.263	Capra_hircus
ENSG00000093167	LRRFIP2	99	42.791	ENSTSYG00000027367	-	99	43.471	Carlito_syrichta
ENSG00000093167	LRRFIP2	100	97.877	ENSTSYG00000005420	LRRFIP2	100	97.877	Carlito_syrichta
ENSG00000093167	LRRFIP2	99	73.861	ENSCAPG00000000393	-	79	94.872	Cavia_aperea
ENSG00000093167	LRRFIP2	100	72.881	ENSCPOG00000006777	-	99	71.667	Cavia_porcellus
ENSG00000093167	LRRFIP2	100	98.795	ENSCPOG00000038703	LRRFIP2	100	98.349	Cavia_porcellus
ENSG00000093167	LRRFIP2	100	98.507	ENSCCAG00000033053	-	100	99.492	Cebus_capucinus
ENSG00000093167	LRRFIP2	100	77.966	ENSCCAG00000003358	LRRFIP1	90	57.064	Cebus_capucinus
ENSG00000093167	LRRFIP2	100	85.000	ENSCCAG00000031402	-	99	92.593	Cebus_capucinus
ENSG00000093167	LRRFIP2	100	77.966	ENSCATG00000040003	LRRFIP1	99	48.714	Cercocebus_atys
ENSG00000093167	LRRFIP2	100	99.764	ENSCATG00000043657	LRRFIP2	100	99.764	Cercocebus_atys
ENSG00000093167	LRRFIP2	88	59.259	ENSCLAG00000002231	-	96	59.318	Chinchilla_lanigera
ENSG00000093167	LRRFIP2	100	99.111	ENSCLAG00000003180	LRRFIP2	100	99.057	Chinchilla_lanigera
ENSG00000093167	LRRFIP2	100	98.305	ENSCSAG00000014156	LRRFIP2	100	95.027	Chlorocebus_sabaeus
ENSG00000093167	LRRFIP2	99	42.326	ENSCSAG00000006108	-	94	57.981	Chlorocebus_sabaeus
ENSG00000093167	LRRFIP2	100	98.795	ENSCHOG00000002646	LRRFIP2	100	74.064	Choloepus_hoffmanni
ENSG00000093167	LRRFIP2	97	42.654	ENSCPBG00000010749	LRRFIP1	95	46.793	Chrysemys_picta_bellii
ENSG00000093167	LRRFIP2	100	96.610	ENSCPBG00000013573	LRRFIP2	100	96.610	Chrysemys_picta_bellii
ENSG00000093167	LRRFIP2	93	65.455	ENSCING00000013021	-	99	41.309	Ciona_intestinalis
ENSG00000093167	LRRFIP2	100	99.764	ENSCANG00000039614	LRRFIP2	100	99.764	Colobus_angolensis_palliatus
ENSG00000093167	LRRFIP2	99	42.791	ENSCANG00000039607	LRRFIP1	97	45.547	Colobus_angolensis_palliatus
ENSG00000093167	LRRFIP2	100	96.889	ENSCGRG00001011695	Lrrfip2	100	95.755	Cricetulus_griseus_chok1gshd
ENSG00000093167	LRRFIP2	86	58.289	ENSCGRG00001024654	-	100	58.289	Cricetulus_griseus_chok1gshd
ENSG00000093167	LRRFIP2	88	59.115	ENSCGRG00000010555	-	96	59.173	Cricetulus_griseus_crigri
ENSG00000093167	LRRFIP2	100	96.889	ENSCGRG00000001645	Lrrfip2	100	95.755	Cricetulus_griseus_crigri
ENSG00000093167	LRRFIP2	100	91.525	ENSCSEG00000017449	lrrfip2	100	91.525	Cynoglossus_semilaevis
ENSG00000093167	LRRFIP2	97	71.930	ENSCSEG00000009064	-	100	43.237	Cynoglossus_semilaevis
ENSG00000093167	LRRFIP2	100	91.667	ENSCVAG00000000131	lrrfip2	100	91.525	Cyprinodon_variegatus
ENSG00000093167	LRRFIP2	100	79.661	ENSCVAG00000000923	-	99	79.661	Cyprinodon_variegatus
ENSG00000093167	LRRFIP2	89	43.006	ENSCVAG00000004618	-	84	43.923	Cyprinodon_variegatus
ENSG00000093167	LRRFIP2	100	91.525	ENSDARG00000010400	lrrfip2	100	91.525	Danio_rerio
ENSG00000093167	LRRFIP2	100	72.881	ENSDARG00000030012	lrrfip1a	91	72.131	Danio_rerio
ENSG00000093167	LRRFIP2	100	72.881	ENSDARG00000095170	lrrfip1b	100	55.556	Danio_rerio
ENSG00000093167	LRRFIP2	88	57.292	ENSDNOG00000045810	LRRFIP1	91	57.364	Dasypus_novemcinctus
ENSG00000093167	LRRFIP2	100	97.590	ENSDNOG00000018861	LRRFIP2	100	89.247	Dasypus_novemcinctus
ENSG00000093167	LRRFIP2	100	98.667	ENSDORG00000005832	Lrrfip2	100	98.592	Dipodomys_ordii
ENSG00000093167	LRRFIP2	88	59.103	ENSDORG00000013588	-	96	59.162	Dipodomys_ordii
ENSG00000093167	LRRFIP2	99	43.099	FBgn0030699	CG8578	98	43.099	Drosophila_melanogaster
ENSG00000093167	LRRFIP2	100	96.610	ENSETEG00000014928	LRRFIP2	90	78.308	Echinops_telfairi
ENSG00000093167	LRRFIP2	97	42.095	ENSEBUG00000017057	lrrfip2	99	42.135	Eptatretus_burgeri
ENSG00000093167	LRRFIP2	100	76.271	ENSEBUG00000008369	lrrfip2	99	75.000	Eptatretus_burgeri
ENSG00000093167	LRRFIP2	100	77.966	ENSEASG00005007354	LRRFIP1	95	58.261	Equus_asinus_asinus
ENSG00000093167	LRRFIP2	100	97.590	ENSEASG00005007395	LRRFIP2	100	90.323	Equus_asinus_asinus
ENSG00000093167	LRRFIP2	100	98.193	ENSECAG00000021270	LRRFIP2	98	96.610	Equus_caballus
ENSG00000093167	LRRFIP2	100	98.795	ENSEEUG00000013415	LRRFIP2	100	86.011	Erinaceus_europaeus
ENSG00000093167	LRRFIP2	100	79.661	ENSELUG00000009514	lrrfip1a	99	47.995	Esox_lucius
ENSG00000093167	LRRFIP2	100	93.333	ENSELUG00000012027	lrrfip2	100	93.220	Esox_lucius
ENSG00000093167	LRRFIP2	100	73.770	ENSELUG00000002824	-	97	73.016	Esox_lucius
ENSG00000093167	LRRFIP2	100	77.966	ENSFCAG00000012725	-	99	76.667	Felis_catus
ENSG00000093167	LRRFIP2	100	98.795	ENSFCAG00000001374	LRRFIP2	100	95.991	Felis_catus
ENSG00000093167	LRRFIP2	99	73.585	ENSFALG00000012219	LRRFIP2	100	80.622	Ficedula_albicollis
ENSG00000093167	LRRFIP2	93	46.903	ENSFALG00000012789	LRRFIP1	95	46.812	Ficedula_albicollis
ENSG00000093167	LRRFIP2	88	59.682	ENSFDAG00000016768	-	96	59.737	Fukomys_damarensis
ENSG00000093167	LRRFIP2	100	98.585	ENSFDAG00000014737	-	100	98.585	Fukomys_damarensis
ENSG00000093167	LRRFIP2	100	66.750	ENSFDAG00000006567	-	100	67.250	Fukomys_damarensis
ENSG00000093167	LRRFIP2	100	89.831	ENSFHEG00000019301	lrrfip2	100	84.615	Fundulus_heteroclitus
ENSG00000093167	LRRFIP2	96	40.865	ENSGMOG00000011245	-	71	53.412	Gadus_morhua
ENSG00000093167	LRRFIP2	100	89.831	ENSGMOG00000016309	lrrfip2	100	62.550	Gadus_morhua
ENSG00000093167	LRRFIP2	100	43.250	ENSGMOG00000015295	lrrfip1b	100	43.250	Gadus_morhua
ENSG00000093167	LRRFIP2	100	96.610	ENSGALG00000033102	LRRFIP2	100	96.610	Gallus_gallus
ENSG00000093167	LRRFIP2	100	76.271	ENSGALG00000003862	LRRFIP1	100	47.530	Gallus_gallus
ENSG00000093167	LRRFIP2	100	76.271	ENSGAFG00000000049	lrrfip1b	100	76.271	Gambusia_affinis
ENSG00000093167	LRRFIP2	100	89.831	ENSGAFG00000017819	lrrfip2	100	89.831	Gambusia_affinis
ENSG00000093167	LRRFIP2	100	76.271	ENSGAFG00000011211	lrrfip1a	99	46.583	Gambusia_affinis
ENSG00000093167	LRRFIP2	100	76.271	ENSGACG00000001620	-	95	75.410	Gasterosteus_aculeatus
ENSG00000093167	LRRFIP2	100	88.136	ENSGACG00000003611	lrrfip2	100	86.667	Gasterosteus_aculeatus
ENSG00000093167	LRRFIP2	100	66.102	ENSGACG00000015498	-	100	51.244	Gasterosteus_aculeatus
ENSG00000093167	LRRFIP2	100	94.915	ENSGAGG00000025455	LRRFIP2	100	94.915	Gopherus_agassizii
ENSG00000093167	LRRFIP2	100	99.764	ENSGGOG00000001784	LRRFIP2	100	99.764	Gorilla_gorilla
ENSG00000093167	LRRFIP2	88	55.307	ENSGGOG00000008411	LRRFIP1	90	55.402	Gorilla_gorilla
ENSG00000093167	LRRFIP2	100	52.340	ENSHBUG00000015052	-	100	50.758	Haplochromis_burtoni
ENSG00000093167	LRRFIP2	100	76.271	ENSHBUG00000001453	-	78	52.542	Haplochromis_burtoni
ENSG00000093167	LRRFIP2	100	89.831	ENSHBUG00000010983	lrrfip2	99	89.831	Haplochromis_burtoni
ENSG00000093167	LRRFIP2	100	98.305	ENSHGLG00000003324	-	100	95.500	Heterocephalus_glaber_female
ENSG00000093167	LRRFIP2	100	74.576	ENSHGLG00000003183	-	99	59.485	Heterocephalus_glaber_female
ENSG00000093167	LRRFIP2	100	89.831	ENSHGLG00000001426	-	100	89.831	Heterocephalus_glaber_female
ENSG00000093167	LRRFIP2	100	81.500	ENSHGLG00000000781	-	100	81.500	Heterocephalus_glaber_female
ENSG00000093167	LRRFIP2	88	57.937	ENSHGLG00100003840	-	96	58.005	Heterocephalus_glaber_male
ENSG00000093167	LRRFIP2	100	83.750	ENSHGLG00100000305	-	100	83.750	Heterocephalus_glaber_male
ENSG00000093167	LRRFIP2	100	89.831	ENSHGLG00100013430	-	82	90.217	Heterocephalus_glaber_male
ENSG00000093167	LRRFIP2	100	81.750	ENSHGLG00100006585	-	100	81.750	Heterocephalus_glaber_male
ENSG00000093167	LRRFIP2	100	98.305	ENSHGLG00100012760	-	100	95.181	Heterocephalus_glaber_male
ENSG00000093167	LRRFIP2	100	77.966	ENSHCOG00000010534	LRRFIP1	99	56.349	Hippocampus_comes
ENSG00000093167	LRRFIP2	100	88.136	ENSHCOG00000004180	lrrfip2	100	88.136	Hippocampus_comes
ENSG00000093167	LRRFIP2	100	76.271	ENSIPUG00000012031	-	97	75.410	Ictalurus_punctatus
ENSG00000093167	LRRFIP2	100	93.333	ENSIPUG00000014421	lrrfip2	91	91.667	Ictalurus_punctatus
ENSG00000093167	LRRFIP2	88	60.053	ENSSTOG00000028433	-	96	60.209	Ictidomys_tridecemlineatus
ENSG00000093167	LRRFIP2	100	98.667	ENSSTOG00000023775	LRRFIP2	100	97.642	Ictidomys_tridecemlineatus
ENSG00000093167	LRRFIP2	100	96.934	ENSJJAG00000014566	Lrrfip2	100	96.934	Jaculus_jaculus
ENSG00000093167	LRRFIP2	100	89.831	ENSKMAG00000008669	lrrfip2	100	89.831	Kryptolebias_marmoratus
ENSG00000093167	LRRFIP2	100	76.271	ENSLBEG00000027720	lrrfip1a	99	58.810	Labrus_bergylta
ENSG00000093167	LRRFIP2	99	66.298	ENSLBEG00000007127	-	98	46.596	Labrus_bergylta
ENSG00000093167	LRRFIP2	100	93.220	ENSLBEG00000013227	lrrfip2	100	91.803	Labrus_bergylta
ENSG00000093167	LRRFIP2	100	93.220	ENSLACG00000008329	LRRFIP2	100	73.933	Latimeria_chalumnae
ENSG00000093167	LRRFIP2	100	74.576	ENSLACG00000009375	-	90	56.742	Latimeria_chalumnae
ENSG00000093167	LRRFIP2	100	93.220	ENSLOCG00000004883	lrrfip2	100	70.366	Lepisosteus_oculatus
ENSG00000093167	LRRFIP2	100	76.271	ENSLOCG00000004973	lrrfip1b	73	76.271	Lepisosteus_oculatus
ENSG00000093167	LRRFIP2	100	98.795	ENSLAFG00000016834	LRRFIP2	100	89.320	Loxodonta_africana
ENSG00000093167	LRRFIP2	99	41.096	ENSLAFG00000015782	-	92	48.301	Loxodonta_africana
ENSG00000093167	LRRFIP2	100	77.966	ENSMFAG00000035972	LRRFIP1	99	47.814	Macaca_fascicularis
ENSG00000093167	LRRFIP2	100	99.764	ENSMFAG00000032193	LRRFIP2	100	99.764	Macaca_fascicularis
ENSG00000093167	LRRFIP2	100	77.966	ENSMMUG00000003386	LRRFIP1	99	47.196	Macaca_mulatta
ENSG00000093167	LRRFIP2	100	99.556	ENSMMUG00000022539	LRRFIP2	100	99.528	Macaca_mulatta
ENSG00000093167	LRRFIP2	100	77.966	ENSMNEG00000034659	LRRFIP1	99	47.469	Macaca_nemestrina
ENSG00000093167	LRRFIP2	100	99.764	ENSMNEG00000044558	LRRFIP2	100	99.764	Macaca_nemestrina
ENSG00000093167	LRRFIP2	100	99.764	ENSMLEG00000043789	LRRFIP2	100	99.764	Mandrillus_leucophaeus
ENSG00000093167	LRRFIP2	99	42.791	ENSMLEG00000038517	LRRFIP1	97	45.693	Mandrillus_leucophaeus
ENSG00000093167	LRRFIP2	100	72.881	ENSMAMG00000022660	lrrfip1b	100	47.640	Mastacembelus_armatus
ENSG00000093167	LRRFIP2	100	90.000	ENSMAMG00000015529	lrrfip2	100	89.831	Mastacembelus_armatus
ENSG00000093167	LRRFIP2	100	89.831	ENSMZEG00005010968	lrrfip2	99	89.831	Maylandia_zebra
ENSG00000093167	LRRFIP2	100	76.271	ENSMZEG00005013703	-	99	48.163	Maylandia_zebra
ENSG00000093167	LRRFIP2	100	96.610	ENSMGAG00000012175	LRRFIP2	100	77.254	Meleagris_gallopavo
ENSG00000093167	LRRFIP2	97	42.723	ENSMGAG00000003145	LRRFIP1	94	46.299	Meleagris_gallopavo
ENSG00000093167	LRRFIP2	100	77.966	ENSMAUG00000008054	-	99	76.667	Mesocricetus_auratus
ENSG00000093167	LRRFIP2	100	98.222	ENSMAUG00000014279	Lrrfip2	100	96.226	Mesocricetus_auratus
ENSG00000093167	LRRFIP2	100	98.821	ENSMICG00000048972	LRRFIP2	100	98.821	Microcebus_murinus
ENSG00000093167	LRRFIP2	100	79.661	ENSMICG00000031882	-	99	48.370	Microcebus_murinus
ENSG00000093167	LRRFIP2	100	77.966	ENSMOCG00000017590	-	99	76.667	Microtus_ochrogaster
ENSG00000093167	LRRFIP2	100	98.222	ENSMOCG00000015703	Lrrfip2	100	96.250	Microtus_ochrogaster
ENSG00000093167	LRRFIP2	100	91.525	ENSMMOG00000008513	lrrfip2	98	91.525	Mola_mola
ENSG00000093167	LRRFIP2	100	74.576	ENSMMOG00000019255	LRRFIP1	99	54.878	Mola_mola
ENSG00000093167	LRRFIP2	100	98.305	ENSMODG00000013326	LRRFIP2	100	80.583	Monodelphis_domestica
ENSG00000093167	LRRFIP2	100	72.881	ENSMALG00000001510	lrrfip1b	96	72.131	Monopterus_albus
ENSG00000093167	LRRFIP2	100	91.525	ENSMALG00000007335	lrrfip2	100	91.525	Monopterus_albus
ENSG00000093167	LRRFIP2	100	98.795	MGP_CAROLIEiJ_G0032754	-	100	99.123	Mus_caroli
ENSG00000093167	LRRFIP2	100	77.966	MGP_CAROLIEiJ_G0014414	Lrrfip1	99	62.061	Mus_caroli
ENSG00000093167	LRRFIP2	100	77.966	ENSMUSG00000026305	Lrrfip1	99	61.827	Mus_musculus
ENSG00000093167	LRRFIP2	100	98.795	ENSMUSG00000032497	Lrrfip2	100	99.123	Mus_musculus
ENSG00000093167	LRRFIP2	100	77.966	MGP_PahariEiJ_G0027650	Lrrfip1	99	62.295	Mus_pahari
ENSG00000093167	LRRFIP2	100	98.795	MGP_PahariEiJ_G0015621	Lrrfip2	100	99.123	Mus_pahari
ENSG00000093167	LRRFIP2	100	98.222	MGP_SPRETEiJ_G0033902	Lrrfip2	100	99.123	Mus_spretus
ENSG00000093167	LRRFIP2	100	77.966	MGP_SPRETEiJ_G0015218	Lrrfip1	99	62.061	Mus_spretus
ENSG00000093167	LRRFIP2	100	98.795	ENSMPUG00000002904	LRRFIP2	100	85.753	Mustela_putorius_furo
ENSG00000093167	LRRFIP2	100	77.966	ENSMPUG00000000081	-	100	45.640	Mustela_putorius_furo
ENSG00000093167	LRRFIP2	100	99.398	ENSMLUG00000003572	LRRFIP2	100	92.956	Myotis_lucifugus
ENSG00000093167	LRRFIP2	99	41.395	ENSMLUG00000002001	-	94	44.523	Myotis_lucifugus
ENSG00000093167	LRRFIP2	100	97.778	ENSNGAG00000018995	Lrrfip2	100	97.170	Nannospalax_galili
ENSG00000093167	LRRFIP2	100	76.271	ENSNGAG00000010993	-	99	61.124	Nannospalax_galili
ENSG00000093167	LRRFIP2	100	89.831	ENSNBRG00000016274	lrrfip2	99	89.831	Neolamprologus_brichardi
ENSG00000093167	LRRFIP2	100	99.556	ENSNLEG00000004992	LRRFIP2	100	99.528	Nomascus_leucogenys
ENSG00000093167	LRRFIP2	99	43.256	ENSNLEG00000011097	-	97	45.693	Nomascus_leucogenys
ENSG00000093167	LRRFIP2	93	96.667	ENSMEUG00000012294	LRRFIP2	100	74.341	Notamacropus_eugenii
ENSG00000093167	LRRFIP2	100	98.305	ENSOPRG00000010712	LRRFIP2	100	76.838	Ochotona_princeps
ENSG00000093167	LRRFIP2	96	77.023	ENSODEG00000000022	-	99	74.413	Octodon_degus
ENSG00000093167	LRRFIP2	100	98.305	ENSODEG00000006044	-	100	98.113	Octodon_degus
ENSG00000093167	LRRFIP2	100	76.271	ENSONIG00000016777	LRRFIP1	99	45.034	Oreochromis_niloticus
ENSG00000093167	LRRFIP2	98	34.389	ENSONIG00000019178	-	67	47.511	Oreochromis_niloticus
ENSG00000093167	LRRFIP2	100	86.667	ENSONIG00000010248	lrrfip2	100	86.441	Oreochromis_niloticus
ENSG00000093167	LRRFIP2	100	74.576	ENSOANG00000011499	-	99	46.667	Ornithorhynchus_anatinus
ENSG00000093167	LRRFIP2	100	96.610	ENSOANG00000015304	LRRFIP2	100	77.992	Ornithorhynchus_anatinus
ENSG00000093167	LRRFIP2	97	42.308	ENSOCUG00000027499	-	94	45.389	Oryctolagus_cuniculus
ENSG00000093167	LRRFIP2	100	98.305	ENSOCUG00000003169	LRRFIP2	100	91.123	Oryctolagus_cuniculus
ENSG00000093167	LRRFIP2	100	88.333	ENSORLG00000023564	lrrfip2	100	88.136	Oryzias_latipes
ENSG00000093167	LRRFIP2	100	77.966	ENSORLG00000024134	-	99	50.311	Oryzias_latipes
ENSG00000093167	LRRFIP2	100	88.333	ENSORLG00020005708	lrrfip2	100	88.136	Oryzias_latipes_hni
ENSG00000093167	LRRFIP2	100	77.966	ENSORLG00020010638	-	99	50.311	Oryzias_latipes_hni
ENSG00000093167	LRRFIP2	100	88.333	ENSORLG00015020925	lrrfip2	100	88.136	Oryzias_latipes_hsok
ENSG00000093167	LRRFIP2	100	75.000	ENSORLG00015011013	-	98	53.030	Oryzias_latipes_hsok
ENSG00000093167	LRRFIP2	100	77.966	ENSORLG00015006650	-	99	45.530	Oryzias_latipes_hsok
ENSG00000093167	LRRFIP2	100	77.966	ENSOMEG00000013282	-	99	77.966	Oryzias_melastigma
ENSG00000093167	LRRFIP2	100	72.881	ENSOMEG00000007133	-	94	72.131	Oryzias_melastigma
ENSG00000093167	LRRFIP2	100	88.136	ENSOMEG00000017368	lrrfip2	100	88.136	Oryzias_melastigma
ENSG00000093167	LRRFIP2	100	98.305	ENSOGAG00000008423	LRRFIP2	100	94.036	Otolemur_garnettii
ENSG00000093167	LRRFIP2	98	43.396	ENSOGAG00000013001	-	94	45.739	Otolemur_garnettii
ENSG00000093167	LRRFIP2	100	99.398	ENSOARG00000016501	LRRFIP2	100	90.846	Ovis_aries
ENSG00000093167	LRRFIP2	88	58.192	ENSOARG00000019011	LRRFIP1	90	58.263	Ovis_aries
ENSG00000093167	LRRFIP2	99	42.326	ENSPPAG00000027436	LRRFIP1	97	45.547	Pan_paniscus
ENSG00000093167	LRRFIP2	100	99.764	ENSPPAG00000039105	LRRFIP2	100	99.764	Pan_paniscus
ENSG00000093167	LRRFIP2	96	42.788	ENSPPRG00000005304	-	93	44.978	Panthera_pardus
ENSG00000093167	LRRFIP2	100	98.507	ENSPPRG00000012905	LRRFIP2	100	95.519	Panthera_pardus
ENSG00000093167	LRRFIP2	100	98.305	ENSPTIG00000007303	LRRFIP2	100	85.576	Panthera_tigris_altaica
ENSG00000093167	LRRFIP2	100	77.966	ENSPTRG00000013077	LRRFIP1	99	47.743	Pan_troglodytes
ENSG00000093167	LRRFIP2	100	99.764	ENSPTRG00000014745	LRRFIP2	100	99.764	Pan_troglodytes
ENSG00000093167	LRRFIP2	100	99.764	ENSPANG00000017239	LRRFIP2	100	99.764	Papio_anubis
ENSG00000093167	LRRFIP2	100	77.966	ENSPANG00000017841	LRRFIP1	99	48.087	Papio_anubis
ENSG00000093167	LRRFIP2	100	94.915	ENSPKIG00000021339	lrrfip2	93	94.915	Paramormyrops_kingsleyae
ENSG00000093167	LRRFIP2	100	93.220	ENSPSIG00000011795	LRRFIP2	100	71.081	Pelodiscus_sinensis
ENSG00000093167	LRRFIP2	86	58.602	ENSPSIG00000016774	LRRFIP1	98	45.049	Pelodiscus_sinensis
ENSG00000093167	LRRFIP2	100	89.831	ENSPMGG00000022091	lrrfip2	100	88.333	Periophthalmus_magnuspinnatus
ENSG00000093167	LRRFIP2	100	96.610	ENSPEMG00000023258	Lrrfip2	100	93.285	Peromyscus_maniculatus_bairdii
ENSG00000093167	LRRFIP2	100	77.966	ENSPEMG00000022605	-	99	60.780	Peromyscus_maniculatus_bairdii
ENSG00000093167	LRRFIP2	77	56.044	ENSPMAG00000009592	lrrfip1b	96	41.991	Petromyzon_marinus
ENSG00000093167	LRRFIP2	99	50.000	ENSPMAG00000004338	lrrfip2	100	52.743	Petromyzon_marinus
ENSG00000093167	LRRFIP2	100	96.610	ENSPCIG00000021630	LRRFIP2	100	96.610	Phascolarctos_cinereus
ENSG00000093167	LRRFIP2	100	77.966	ENSPCIG00000021565	-	99	48.365	Phascolarctos_cinereus
ENSG00000093167	LRRFIP2	96	43.902	ENSPFOG00000011768	-	90	56.724	Poecilia_formosa
ENSG00000093167	LRRFIP2	88	41.020	ENSPFOG00000005385	lrrfip1b	99	42.380	Poecilia_formosa
ENSG00000093167	LRRFIP2	100	91.525	ENSPFOG00000013393	lrrfip2	91	69.849	Poecilia_formosa
ENSG00000093167	LRRFIP2	100	91.525	ENSPLAG00000021877	lrrfip2	100	91.525	Poecilia_latipinna
ENSG00000093167	LRRFIP2	100	76.271	ENSPLAG00000009833	-	96	76.271	Poecilia_latipinna
ENSG00000093167	LRRFIP2	100	91.525	ENSPMEG00000020774	lrrfip2	100	91.525	Poecilia_mexicana
ENSG00000093167	LRRFIP2	88	48.169	ENSPMEG00000011611	lrrfip1b	97	45.290	Poecilia_mexicana
ENSG00000093167	LRRFIP2	100	91.667	ENSPREG00000001389	lrrfip2	100	91.525	Poecilia_reticulata
ENSG00000093167	LRRFIP2	100	77.966	ENSPPYG00000013313	-	90	58.261	Pongo_abelii
ENSG00000093167	LRRFIP2	100	98.305	ENSPPYG00000014020	LRRFIP2	100	95.565	Pongo_abelii
ENSG00000093167	LRRFIP2	89	93.333	ENSPCAG00000006660	LRRFIP2	100	72.715	Procavia_capensis
ENSG00000093167	LRRFIP2	100	92.217	ENSPCOG00000017954	LRRFIP2	100	91.981	Propithecus_coquereli
ENSG00000093167	LRRFIP2	100	79.661	ENSPCOG00000024174	-	99	48.630	Propithecus_coquereli
ENSG00000093167	LRRFIP2	100	98.193	ENSPVAG00000005088	LRRFIP2	100	87.795	Pteropus_vampyrus
ENSG00000093167	LRRFIP2	100	90.000	ENSPNYG00000012284	lrrfip2	99	89.831	Pundamilia_nyererei
ENSG00000093167	LRRFIP2	100	77.966	ENSPNAG00000009198	lrrfip1b	100	53.425	Pygocentrus_nattereri
ENSG00000093167	LRRFIP2	100	93.220	ENSPNAG00000007040	lrrfip2	99	93.220	Pygocentrus_nattereri
ENSG00000093167	LRRFIP2	100	74.576	ENSPNAG00000000441	-	99	55.610	Pygocentrus_nattereri
ENSG00000093167	LRRFIP2	100	96.610	ENSRNOG00000021047	Lrrfip2	100	88.101	Rattus_norvegicus
ENSG00000093167	LRRFIP2	100	98.507	ENSRBIG00000044613	LRRFIP2	100	96.934	Rhinopithecus_bieti
ENSG00000093167	LRRFIP2	99	42.326	ENSRBIG00000041081	LRRFIP1	73	58.571	Rhinopithecus_bieti
ENSG00000093167	LRRFIP2	100	99.556	ENSRROG00000032750	LRRFIP2	100	99.528	Rhinopithecus_roxellana
ENSG00000093167	LRRFIP2	99	42.326	ENSRROG00000004323	LRRFIP1	94	45.627	Rhinopithecus_roxellana
ENSG00000093167	LRRFIP2	88	57.939	ENSSBOG00000021844	LRRFIP1	90	58.011	Saimiri_boliviensis_boliviensis
ENSG00000093167	LRRFIP2	100	99.556	ENSSBOG00000022125	LRRFIP2	100	99.292	Saimiri_boliviensis_boliviensis
ENSG00000093167	LRRFIP2	100	98.305	ENSSHAG00000003269	LRRFIP2	100	79.363	Sarcophilus_harrisii
ENSG00000093167	LRRFIP2	88	58.592	ENSSHAG00000007814	-	90	58.659	Sarcophilus_harrisii
ENSG00000093167	LRRFIP2	100	91.525	ENSSFOG00015007418	lrrfip2	100	90.000	Scleropages_formosus
ENSG00000093167	LRRFIP2	100	74.576	ENSSMAG00000000018	-	90	43.478	Scophthalmus_maximus
ENSG00000093167	LRRFIP2	100	91.525	ENSSMAG00000012190	lrrfip2	100	91.525	Scophthalmus_maximus
ENSG00000093167	LRRFIP2	100	76.271	ENSSMAG00000018506	lrrfip1a	99	47.814	Scophthalmus_maximus
ENSG00000093167	LRRFIP2	100	74.576	ENSSDUG00000003894	-	100	49.242	Seriola_dumerili
ENSG00000093167	LRRFIP2	100	91.525	ENSSDUG00000004919	lrrfip2	100	91.525	Seriola_dumerili
ENSG00000093167	LRRFIP2	100	76.271	ENSSDUG00000006643	-	95	75.410	Seriola_dumerili
ENSG00000093167	LRRFIP2	100	91.525	ENSSLDG00000023448	lrrfip2	100	91.525	Seriola_lalandi_dorsalis
ENSG00000093167	LRRFIP2	100	76.271	ENSSLDG00000020928	LRRFIP1	95	75.410	Seriola_lalandi_dorsalis
ENSG00000093167	LRRFIP2	100	74.576	ENSSLDG00000009468	lrrfip1b	100	53.731	Seriola_lalandi_dorsalis
ENSG00000093167	LRRFIP2	94	85.481	ENSSARG00000014379	LRRFIP2	98	85.481	Sorex_araneus
ENSG00000093167	LRRFIP2	100	76.271	ENSSPUG00000015429	LRRFIP1	99	76.271	Sphenodon_punctatus
ENSG00000093167	LRRFIP2	100	96.610	ENSSPUG00000015906	LRRFIP2	100	96.610	Sphenodon_punctatus
ENSG00000093167	LRRFIP2	100	76.271	ENSSPAG00000022636	-	99	54.400	Stegastes_partitus
ENSG00000093167	LRRFIP2	100	91.525	ENSSPAG00000021836	lrrfip2	100	67.666	Stegastes_partitus
ENSG00000093167	LRRFIP2	100	77.966	ENSSSCG00000016330	-	96	77.049	Sus_scrofa
ENSG00000093167	LRRFIP2	100	98.795	ENSSSCG00000027738	LRRFIP2	100	97.170	Sus_scrofa
ENSG00000093167	LRRFIP2	96	43.062	ENSTGUG00000003797	LRRFIP1	95	46.501	Taeniopygia_guttata
ENSG00000093167	LRRFIP2	100	98.305	ENSTGUG00000001878	-	100	72.099	Taeniopygia_guttata
ENSG00000093167	LRRFIP2	69	41.270	ENSTRUG00000008570	-	98	54.435	Takifugu_rubripes
ENSG00000093167	LRRFIP2	100	89.831	ENSTRUG00000017714	lrrfip2	100	89.831	Takifugu_rubripes
ENSG00000093167	LRRFIP2	100	80.328	ENSTNIG00000013102	lrrfip2	100	78.870	Tetraodon_nigroviridis
ENSG00000093167	LRRFIP2	98	45.972	ENSTNIG00000017845	-	96	45.495	Tetraodon_nigroviridis
ENSG00000093167	LRRFIP2	100	94.915	ENSTBEG00000008370	LRRFIP2	100	87.517	Tupaia_belangeri
ENSG00000093167	LRRFIP2	100	99.398	ENSTTRG00000014884	LRRFIP2	100	89.736	Tursiops_truncatus
ENSG00000093167	LRRFIP2	99	79.558	ENSUAMG00000027636	-	100	96.154	Ursus_americanus
ENSG00000093167	LRRFIP2	100	98.667	ENSUMAG00000006338	LRRFIP2	100	95.047	Ursus_maritimus
ENSG00000093167	LRRFIP2	88	56.171	ENSUMAG00000011956	LRRFIP1	91	56.020	Ursus_maritimus
ENSG00000093167	LRRFIP2	100	84.337	ENSVPAG00000006829	LRRFIP2	100	86.900	Vicugna_pacos
ENSG00000093167	LRRFIP2	86	57.527	ENSVVUG00000001547	LRRFIP1	92	44.706	Vulpes_vulpes
ENSG00000093167	LRRFIP2	100	98.667	ENSVVUG00000006679	LRRFIP2	100	96.250	Vulpes_vulpes
ENSG00000093167	LRRFIP2	98	43.602	ENSXETG00000032269	LRRFIP1	97	48.472	Xenopus_tropicalis
ENSG00000093167	LRRFIP2	100	93.220	ENSXETG00000004994	lrrfip2	100	93.220	Xenopus_tropicalis
ENSG00000093167	LRRFIP2	100	90.000	ENSXMAG00000008181	lrrfip2	100	89.831	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	-	ISA	Function
GO:0005515	protein binding	15677333.25416956.	IPI	Function
GO:0005575	cellular_component	-	ND	Component
GO:0006357	regulation of transcription by RNA polymerase II	-	IEA	Process
GO:0008150	biological_process	-	ND	Process
GO:0016055	Wnt signaling pathway	-	IEA	Process
GO:0030275	LRR domain binding	10366446.	IPI	Function