EuRBPDB

Description

Ensembl ID: ENSG00000095319 (Gene tree)
Gene ID: 23511
Gene Symbol: NUP188
Alias: KIAA0169
Full Name: nucleoporin 188
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 59,404 bases
Position: chr9:128,947,693-129,007,096
Accession: 17859
RBP type: non-canonical RBP
Summary: The nuclear pore complex (NPC) is found on the nuclear envelope and forms a gateway that regulates the flow of proteins and RNAs between the cytoplasm and nucleoplasm. The NPC is comprised of approximately 30 distinct proteins collectively known as nucleoporins. Nucleoporins are pore-complex-specific glycoproteins which often have cytoplasmically oriented O-linked N-acetylglucosamine residues and numerous repeats of the pentapeptide sequence XFXFG. However, the nucleoporin protein encoded by this gene does not contain the typical FG repeat sequences found in most vertebrate nucleoporins. This nucleoporin is thought to form part of the scaffold for the central channel of the nuclear pore. [provided by RefSeq, Jan 2013]

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000550219	NUP188-211	886	-	-	- (aa)	-	-
ENST00000485158	NUP188-206	392	-	-	- (aa)	-	-
ENST00000495726	NUP188-210	516	-	-	- (aa)	-	-
ENST00000491990	NUP188-209	381	-	-	- (aa)	-	-
ENST00000467044	NUP188-204	584	-	-	- (aa)	-	-
ENST00000464729	NUP188-202	408	-	-	- (aa)	-	-
ENST00000487952	NUP188-207	568	-	-	- (aa)	-	-
ENST00000465344	NUP188-203	400	-	-	- (aa)	-	-
ENST00000477069	NUP188-205	2941	-	-	- (aa)	-	-
ENST00000372577	NUP188-201	5689	-	ENSP00000361658	1749 (aa)	-	Q5SRE5
ENST00000491502	NUP188-208	534	-	-	- (aa)	-	-

Gene Model

Pathways

Pathway ID	Pathway Name	Source
hsa03013	RNA transport	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000095319	Arterial Pressure	3.6792609E-005	-

Protein-Protein Interaction (PPI)

* RBP PPI network refers to all genes directly bind to RBP

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005635	nuclear envelope	-	TAS	Component
GO:0006110	regulation of glycolytic process	-	TAS	Process
GO:0006406	mRNA export from nucleus	-	TAS	Process
GO:0006409	tRNA export from nucleus	-	TAS	Process
GO:0006606	protein import into nucleus	21873635.	IBA	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0016032	viral process	-	TAS	Process
GO:0016925	protein sumoylation	-	TAS	Process
GO:0017056	structural constituent of nuclear pore	21873635.	IBA	Function
GO:0019083	viral transcription	-	TAS	Process
GO:0043657	host cell	-	IEA	Component
GO:0044611	nuclear pore inner ring	21873635.	IBA	Component
GO:0060964	regulation of gene silencing by miRNA	-	TAS	Process
GO:0075733	intracellular transport of virus	-	TAS	Process
GO:1900034	regulation of cellular response to heat	-	TAS	Process