EuRBPDB

Description

RBDs

RBPome

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000095485 (Gene tree)
Gene ID: 55280
Gene Symbol: CWF19L1
Alias: FLJ10998|hDrn1
Full Name: CWF19 like cell cycle control factor 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 35,386 bases
Position: chr10:100,232,296-100,267,681
Accession: 25613
RBP type: canonical RBP
Summary: This gene encodes a member of the CWF19 protein family. Mutations in this gene have been associated with autosomal recessive spinocerebellar ataxia-17 and mild cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000326411	CwfJ_C_1	PF04677.15	1.6e-33	1	1
ENSP00000326411	CwfJ_C_2	PF04676.14	1.9e-15	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000468709	CWF19L1-204	2402	-	ENSP00000492991	72 (aa)	-	A0A0S2Z5Q6
ENST00000482452	CWF19L1-207	1606	-	ENSP00000492899	96 (aa)	-	A0A286YEP9
ENST00000466408	CWF19L1-202	447	-	-	- (aa)	-	-
ENST00000496796	CWF19L1-208	727	-	-	- (aa)	-	-
ENST00000473842	CWF19L1-205	654	-	ENSP00000493150	193 (aa)	-	A0A286YF56
ENST00000466955	CWF19L1-203	659	-	-	- (aa)	-	-
ENST00000478047	CWF19L1-206	2694	-	-	- (aa)	-	-
ENST00000354105	CWF19L1-201	1815	-	ENSP00000326411	538 (aa)	-	Q69YN2

Gene Model

Click here to download ENSG00000095485's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000095485	Depressive Disorder, Major	4.613E-5	17728769
ENSG00000095485	Platelet Function Tests	3.4600000E-007	-
ENSG00000095485	Platelet Function Tests	3.6800000E-007	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000095485	rs12784396	10	100267650	C	High density lipoprotein cholesterol levels	29507422	unit decrease	0.014	EFO_0004612
ENSG00000095485	rs12784396	10	100267650	C	Total cholesterol levels	29507422	unit decrease	0.02	EFO_0004574
ENSG00000095485	rs12784396	10	100267650	C	Total cholesterol levels	29507422	unit decrease	0.021	EFO_0004574

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000095485's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000095485	CWF19L1	100	65.455	ENSAPOG00000015976	cwf19l1	100	65.455	Acanthochromis_polyacanthus
ENSG00000095485	CWF19L1	100	92.950	ENSAMEG00000006811	CWF19L1	100	92.950	Ailuropoda_melanoleuca
ENSG00000095485	CWF19L1	100	64.801	ENSACIG00000011436	cwf19l1	100	65.343	Amphilophus_citrinellus
ENSG00000095485	CWF19L1	100	65.091	ENSAOCG00000014777	cwf19l1	100	65.091	Amphiprion_ocellaris
ENSG00000095485	CWF19L1	100	64.545	ENSAPEG00000019618	cwf19l1	100	64.545	Amphiprion_percula
ENSG00000095485	CWF19L1	100	64.337	ENSATEG00000021314	cwf19l1	100	64.632	Anabas_testudineus
ENSG00000095485	CWF19L1	85	72.588	ENSAPLG00000011370	CWF19L1	100	72.588	Anas_platyrhynchos
ENSG00000095485	CWF19L1	99	63.024	ENSACAG00000016026	CWF19L1	99	62.842	Anolis_carolinensis
ENSG00000095485	CWF19L1	100	97.398	ENSANAG00000023190	CWF19L1	100	97.398	Aotus_nancymaae
ENSG00000095485	CWF19L1	100	65.766	ENSACLG00000009159	cwf19l1	100	65.766	Astatotilapia_calliptera
ENSG00000095485	CWF19L1	100	66.065	ENSAMXG00000007302	cwf19l1	100	66.065	Astyanax_mexicanus
ENSG00000095485	CWF19L1	100	94.238	ENSBTAG00000007594	CWF19L1	99	94.238	Bos_taurus
ENSG00000095485	CWF19L1	100	42.336	WBGene00017534	F17A9.2	99	41.971	Caenorhabditis_elegans
ENSG00000095485	CWF19L1	100	95.911	ENSCJAG00000017176	CWF19L1	100	95.911	Callithrix_jacchus
ENSG00000095485	CWF19L1	100	94.238	ENSCAFG00000009624	CWF19L1	100	94.238	Canis_familiaris
ENSG00000095485	CWF19L1	100	94.238	ENSCAFG00020008275	CWF19L1	100	94.238	Canis_lupus_dingo
ENSG00000095485	CWF19L1	100	94.238	ENSCHIG00000022368	CWF19L1	99	94.238	Capra_hircus
ENSG00000095485	CWF19L1	100	88.848	ENSTSYG00000012364	CWF19L1	100	90.520	Carlito_syrichta
ENSG00000095485	CWF19L1	90	77.113	ENSCAPG00000011031	CWF19L1	100	76.860	Cavia_aperea
ENSG00000095485	CWF19L1	100	91.078	ENSCPOG00000010890	CWF19L1	100	91.078	Cavia_porcellus
ENSG00000095485	CWF19L1	100	97.584	ENSCCAG00000031321	CWF19L1	100	97.584	Cebus_capucinus
ENSG00000095485	CWF19L1	100	96.840	ENSCATG00000043079	-	100	96.840	Cercocebus_atys
ENSG00000095485	CWF19L1	100	80.617	ENSCATG00000034615	-	99	72.659	Cercocebus_atys
ENSG00000095485	CWF19L1	100	91.450	ENSCLAG00000007821	CWF19L1	100	91.450	Chinchilla_lanigera
ENSG00000095485	CWF19L1	100	95.176	ENSCSAG00000005656	CWF19L1	100	95.176	Chlorocebus_sabaeus
ENSG00000095485	CWF19L1	87	82.480	ENSCHOG00000013326	CWF19L1	87	82.480	Choloepus_hoffmanni
ENSG00000095485	CWF19L1	99	75.327	ENSCPBG00000015743	CWF19L1	99	75.327	Chrysemys_picta_bellii
ENSG00000095485	CWF19L1	96	46.992	ENSCING00000002739	-	99	45.971	Ciona_intestinalis
ENSG00000095485	CWF19L1	99	45.338	ENSCSAVG00000001169	-	99	44.689	Ciona_savignyi
ENSG00000095485	CWF19L1	100	96.654	ENSCANG00000037983	CWF19L1	100	96.654	Colobus_angolensis_palliatus
ENSG00000095485	CWF19L1	100	90.520	ENSCGRG00001015704	Cwf19l1	100	90.520	Cricetulus_griseus_chok1gshd
ENSG00000095485	CWF19L1	100	90.520	ENSCGRG00000003911	Cwf19l1	100	90.520	Cricetulus_griseus_crigri
ENSG00000095485	CWF19L1	99	62.050	ENSCSEG00000004325	cwf19l1	99	60.612	Cynoglossus_semilaevis
ENSG00000095485	CWF19L1	89	59.754	ENSCVAG00000005908	cwf19l1	91	59.267	Cyprinodon_variegatus
ENSG00000095485	CWF19L1	100	65.693	ENSDARG00000002128	cwf19l1	100	64.416	Danio_rerio
ENSG00000095485	CWF19L1	93	91.816	ENSDNOG00000036842	CWF19L1	97	92.225	Dasypus_novemcinctus
ENSG00000095485	CWF19L1	100	92.751	ENSDORG00000011967	Cwf19l1	100	92.751	Dipodomys_ordii
ENSG00000095485	CWF19L1	99	38.519	FBgn0033615	CG7741	99	38.148	Drosophila_melanogaster
ENSG00000095485	CWF19L1	100	65.198	ENSETEG00000008460	CWF19L1	73	87.234	Echinops_telfairi
ENSG00000095485	CWF19L1	100	43.929	ENSEBUG00000003141	-	99	45.721	Eptatretus_burgeri
ENSG00000095485	CWF19L1	100	94.796	ENSEASG00005009032	CWF19L1	100	94.796	Equus_asinus_asinus
ENSG00000095485	CWF19L1	100	95.911	ENSECAG00000016333	CWF19L1	100	95.911	Equus_caballus
ENSG00000095485	CWF19L1	100	81.413	ENSEEUG00000014324	CWF19L1	100	81.413	Erinaceus_europaeus
ENSG00000095485	CWF19L1	100	61.071	ENSELUG00000010739	cwf19l1	100	62.118	Esox_lucius
ENSG00000095485	CWF19L1	100	93.866	ENSFCAG00000010585	CWF19L1	100	93.866	Felis_catus
ENSG00000095485	CWF19L1	85	73.846	ENSFALG00000012841	CWF19L1	95	73.846	Ficedula_albicollis
ENSG00000095485	CWF19L1	100	92.007	ENSFDAG00000009400	CWF19L1	100	92.007	Fukomys_damarensis
ENSG00000095485	CWF19L1	100	63.849	ENSFHEG00000009449	cwf19l1	100	64.337	Fundulus_heteroclitus
ENSG00000095485	CWF19L1	99	62.202	ENSGMOG00000013248	cwf19l1	100	61.468	Gadus_morhua
ENSG00000095485	CWF19L1	100	63.043	ENSGAFG00000020887	cwf19l1	100	63.043	Gambusia_affinis
ENSG00000095485	CWF19L1	100	64.738	ENSGACG00000000738	cwf19l1	100	64.738	Gasterosteus_aculeatus
ENSG00000095485	CWF19L1	99	70.280	ENSGAGG00000013262	CWF19L1	99	69.533	Gopherus_agassizii
ENSG00000095485	CWF19L1	100	65.586	ENSHBUG00000006747	cwf19l1	100	65.586	Haplochromis_burtoni
ENSG00000095485	CWF19L1	100	91.078	ENSHGLG00000018918	CWF19L1	100	91.078	Heterocephalus_glaber_female
ENSG00000095485	CWF19L1	100	90.892	ENSHGLG00100006241	CWF19L1	100	90.892	Heterocephalus_glaber_male
ENSG00000095485	CWF19L1	100	62.591	ENSHCOG00000004362	cwf19l1	100	61.314	Hippocampus_comes
ENSG00000095485	CWF19L1	100	65.530	ENSIPUG00000016884	cwf19l1	100	65.530	Ictalurus_punctatus
ENSG00000095485	CWF19L1	100	93.309	ENSSTOG00000005784	CWF19L1	100	93.309	Ictidomys_tridecemlineatus
ENSG00000095485	CWF19L1	100	92.565	ENSJJAG00000015368	Cwf19l1	100	92.565	Jaculus_jaculus
ENSG00000095485	CWF19L1	100	63.784	ENSKMAG00000009649	cwf19l1	100	62.703	Kryptolebias_marmoratus
ENSG00000095485	CWF19L1	69	73.243	ENSLACG00000000333	-	100	70.811	Latimeria_chalumnae
ENSG00000095485	CWF19L1	100	68.066	ENSLOCG00000017035	cwf19l1	100	66.909	Lepisosteus_oculatus
ENSG00000095485	CWF19L1	100	92.379	ENSLAFG00000014975	CWF19L1	100	92.379	Loxodonta_africana
ENSG00000095485	CWF19L1	100	96.840	ENSMFAG00000031202	-	100	96.840	Macaca_fascicularis
ENSG00000095485	CWF19L1	100	90.892	ENSMFAG00000040442	-	100	90.335	Macaca_fascicularis
ENSG00000095485	CWF19L1	100	96.654	ENSMMUG00000018472	CWF19L1	100	96.654	Macaca_mulatta
ENSG00000095485	CWF19L1	100	91.078	ENSMMUG00000011382	-	100	90.520	Macaca_mulatta
ENSG00000095485	CWF19L1	87	97.938	ENSMNEG00000028051	-	100	97.938	Macaca_nemestrina
ENSG00000095485	CWF19L1	100	88.848	ENSMNEG00000036357	-	100	88.290	Macaca_nemestrina
ENSG00000095485	CWF19L1	100	89.405	ENSMLEG00000036355	CWF19L1	100	89.405	Mandrillus_leucophaeus
ENSG00000095485	CWF19L1	100	64.195	ENSMAMG00000019265	cwf19l1	100	64.195	Mastacembelus_armatus
ENSG00000095485	CWF19L1	100	65.766	ENSMZEG00005016021	cwf19l1	100	65.766	Maylandia_zebra
ENSG00000095485	CWF19L1	100	55.263	ENSMGAG00000002075	CWF19L1	100	68.683	Meleagris_gallopavo
ENSG00000095485	CWF19L1	99	89.811	ENSMAUG00000016480	Cwf19l1	100	89.811	Mesocricetus_auratus
ENSG00000095485	CWF19L1	100	94.052	ENSMICG00000034162	CWF19L1	100	94.052	Microcebus_murinus
ENSG00000095485	CWF19L1	100	90.335	ENSMOCG00000021513	Cwf19l1	100	90.335	Microtus_ochrogaster
ENSG00000095485	CWF19L1	99	61.261	ENSMMOG00000006088	cwf19l1	99	62.703	Mola_mola
ENSG00000095485	CWF19L1	100	81.970	ENSMODG00000010572	CWF19L1	100	82.189	Monodelphis_domestica
ENSG00000095485	CWF19L1	98	65.448	ENSMALG00000003265	cwf19l1	99	65.265	Monopterus_albus
ENSG00000095485	CWF19L1	100	90.335	MGP_CAROLIEiJ_G0022992	Cwf19l1	100	90.335	Mus_caroli
ENSG00000095485	CWF19L1	100	89.219	ENSMUSG00000025200	Cwf19l1	100	89.219	Mus_musculus
ENSG00000095485	CWF19L1	100	89.591	MGP_PahariEiJ_G0014482	Cwf19l1	100	89.591	Mus_pahari
ENSG00000095485	CWF19L1	100	89.777	MGP_SPRETEiJ_G0023913	Cwf19l1	100	89.777	Mus_spretus
ENSG00000095485	CWF19L1	100	93.866	ENSMPUG00000016977	CWF19L1	100	93.866	Mustela_putorius_furo
ENSG00000095485	CWF19L1	100	94.052	ENSMLUG00000016506	CWF19L1	100	94.052	Myotis_lucifugus
ENSG00000095485	CWF19L1	100	91.450	ENSNGAG00000021145	Cwf19l1	100	91.450	Nannospalax_galili
ENSG00000095485	CWF19L1	100	65.225	ENSNBRG00000014972	cwf19l1	100	65.225	Neolamprologus_brichardi
ENSG00000095485	CWF19L1	99	96.610	ENSNLEG00000014744	CWF19L1	99	96.610	Nomascus_leucogenys
ENSG00000095485	CWF19L1	80	85.000	ENSMEUG00000016348	CWF19L1	86	85.000	Notamacropus_eugenii
ENSG00000095485	CWF19L1	100	85.502	ENSOPRG00000005680	CWF19L1	100	85.502	Ochotona_princeps
ENSG00000095485	CWF19L1	100	90.706	ENSODEG00000017213	CWF19L1	100	90.706	Octodon_degus
ENSG00000095485	CWF19L1	99	65.580	ENSONIG00000009944	cwf19l1	99	64.130	Oreochromis_niloticus
ENSG00000095485	CWF19L1	100	78.625	ENSOANG00000002486	CWF19L1	100	78.625	Ornithorhynchus_anatinus
ENSG00000095485	CWF19L1	100	93.002	ENSOCUG00000013130	CWF19L1	100	91.697	Oryctolagus_cuniculus
ENSG00000095485	CWF19L1	100	63.834	ENSORLG00000017287	cwf19l1	100	63.357	Oryzias_latipes
ENSG00000095485	CWF19L1	100	64.029	ENSORLG00015005168	cwf19l1	100	63.538	Oryzias_latipes_hsok
ENSG00000095485	CWF19L1	100	64.144	ENSOMEG00000023197	cwf19l1	100	63.653	Oryzias_melastigma
ENSG00000095485	CWF19L1	100	87.132	ENSOGAG00000013425	CWF19L1	100	86.949	Otolemur_garnettii
ENSG00000095485	CWF19L1	100	92.421	ENSOARG00000014114	CWF19L1	99	92.052	Ovis_aries
ENSG00000095485	CWF19L1	100	98.885	ENSPPAG00000031948	CWF19L1	100	98.885	Pan_paniscus
ENSG00000095485	CWF19L1	100	93.680	ENSPPRG00000005516	CWF19L1	100	93.680	Panthera_pardus
ENSG00000095485	CWF19L1	100	93.494	ENSPTIG00000009695	CWF19L1	100	93.494	Panthera_tigris_altaica
ENSG00000095485	CWF19L1	100	99.071	ENSPTRG00000002843	CWF19L1	100	99.071	Pan_troglodytes
ENSG00000095485	CWF19L1	100	88.104	ENSPANG00000010712	-	100	88.104	Papio_anubis
ENSG00000095485	CWF19L1	100	96.840	ENSPANG00000021205	-	100	96.840	Papio_anubis
ENSG00000095485	CWF19L1	100	66.302	ENSPKIG00000009086	cwf19l1	100	66.849	Paramormyrops_kingsleyae
ENSG00000095485	CWF19L1	99	73.557	ENSPSIG00000006990	CWF19L1	99	72.439	Pelodiscus_sinensis
ENSG00000095485	CWF19L1	99	63.519	ENSPMGG00000004881	cwf19l1	100	62.222	Periophthalmus_magnuspinnatus
ENSG00000095485	CWF19L1	100	90.520	ENSPEMG00000013069	Cwf19l1	100	90.520	Peromyscus_maniculatus_bairdii
ENSG00000095485	CWF19L1	66	54.987	ENSPMAG00000002331	-	99	53.100	Petromyzon_marinus
ENSG00000095485	CWF19L1	100	80.483	ENSPCIG00000022698	CWF19L1	100	80.519	Phascolarctos_cinereus
ENSG00000095485	CWF19L1	100	64.130	ENSPFOG00000016594	cwf19l1	100	64.130	Poecilia_formosa
ENSG00000095485	CWF19L1	99	63.553	ENSPLAG00000005289	cwf19l1	99	63.553	Poecilia_latipinna
ENSG00000095485	CWF19L1	100	64.130	ENSPMEG00000017406	cwf19l1	100	64.130	Poecilia_mexicana
ENSG00000095485	CWF19L1	100	64.065	ENSPREG00000021583	cwf19l1	100	64.065	Poecilia_reticulata
ENSG00000095485	CWF19L1	100	97.955	ENSPPYG00000002563	CWF19L1	100	97.955	Pongo_abelii
ENSG00000095485	CWF19L1	100	77.093	ENSPCAG00000012404	CWF19L1	84	90.431	Procavia_capensis
ENSG00000095485	CWF19L1	100	94.610	ENSPCOG00000019363	CWF19L1	100	94.610	Propithecus_coquereli
ENSG00000095485	CWF19L1	100	93.309	ENSPVAG00000008028	CWF19L1	100	93.309	Pteropus_vampyrus
ENSG00000095485	CWF19L1	100	65.704	ENSPNYG00000010443	cwf19l1	100	65.704	Pundamilia_nyererei
ENSG00000095485	CWF19L1	100	66.065	ENSPNAG00000017936	cwf19l1	99	66.426	Pygocentrus_nattereri
ENSG00000095485	CWF19L1	100	89.777	ENSRNOG00000012763	Cwf19l1	100	89.777	Rattus_norvegicus
ENSG00000095485	CWF19L1	100	96.654	ENSRBIG00000033458	CWF19L1	100	96.654	Rhinopithecus_bieti
ENSG00000095485	CWF19L1	100	96.654	ENSRROG00000043660	CWF19L1	100	96.654	Rhinopithecus_roxellana
ENSG00000095485	CWF19L1	100	97.212	ENSSBOG00000027396	CWF19L1	100	97.212	Saimiri_boliviensis_boliviensis
ENSG00000095485	CWF19L1	100	81.111	ENSSHAG00000001813	CWF19L1	100	80.297	Sarcophilus_harrisii
ENSG00000095485	CWF19L1	99	67.647	ENSSFOG00015023080	cwf19l1	99	67.463	Scleropages_formosus
ENSG00000095485	CWF19L1	100	63.588	ENSSMAG00000010056	cwf19l1	100	63.943	Scophthalmus_maximus
ENSG00000095485	CWF19L1	100	62.877	ENSSDUG00000013998	cwf19l1	100	63.167	Seriola_dumerili
ENSG00000095485	CWF19L1	100	62.633	ENSSLDG00000017696	cwf19l1	100	62.745	Seriola_lalandi_dorsalis
ENSG00000095485	CWF19L1	78	94.444	ENSSARG00000014052	CWF19L1	86	94.444	Sorex_araneus
ENSG00000095485	CWF19L1	99	72.744	ENSSPUG00000000988	CWF19L1	99	72.744	Sphenodon_punctatus
ENSG00000095485	CWF19L1	100	60.364	ENSSPAG00000010818	cwf19l1	100	60.364	Stegastes_partitus
ENSG00000095485	CWF19L1	100	95.539	ENSSSCG00000010550	CWF19L1	100	95.539	Sus_scrofa
ENSG00000095485	CWF19L1	100	62.903	ENSTRUG00000005661	cwf19l1	100	62.791	Takifugu_rubripes
ENSG00000095485	CWF19L1	100	63.978	ENSTNIG00000018723	cwf19l1	100	64.452	Tetraodon_nigroviridis
ENSG00000095485	CWF19L1	100	75.836	ENSTBEG00000016735	CWF19L1	100	75.836	Tupaia_belangeri
ENSG00000095485	CWF19L1	100	89.963	ENSTTRG00000011886	CWF19L1	100	89.963	Tursiops_truncatus
ENSG00000095485	CWF19L1	100	93.680	ENSUMAG00000022786	CWF19L1	100	93.680	Ursus_maritimus
ENSG00000095485	CWF19L1	56	94.040	ENSVPAG00000010096	CWF19L1	100	94.040	Vicugna_pacos
ENSG00000095485	CWF19L1	100	94.424	ENSVVUG00000024848	CWF19L1	100	94.424	Vulpes_vulpes
ENSG00000095485	CWF19L1	99	69.663	ENSXETG00000003719	cwf19l1	99	69.663	Xenopus_tropicalis
ENSG00000095485	CWF19L1	100	62.222	ENSXCOG00000011764	cwf19l1	100	62.222	Xiphophorus_couchianus
ENSG00000095485	CWF19L1	99	62.970	ENSXMAG00000009283	cwf19l1	99	62.970	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003674	molecular_function	-	ND	Function
GO:0005575	cellular_component	-	ND	Component
GO:0008150	biological_process	-	ND	Process