EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Expression

Transcripts

Gene Model

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000095627 (Gene tree)
Gene ID: 56165
Gene Symbol: TDRD1
Alias: CT41.1
Full Name: tudor domain containing 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Plus strand
Length: 58,228 bases
Position: chr10:114,174,442-114,232,669
Accession: 11712
RBP type: canonical RBP
Summary: This gene encodes a protein containing a tudor domain that is thought to function in the suppression of transposable elements during spermatogenesis. The related protein in mouse forms a complex with piRNAs and Piwi proteins to promote methylation and silencing of target sequences. This gene was observed to be upregulated by ETS transcription factor ERG in prostate tumors. [provided by RefSeq, Sep 2018]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000251864	TUDOR	PF00567.24	6e-131	1	4
ENSP00000251864	TUDOR	PF00567.24	6e-131	2	4
ENSP00000251864	TUDOR	PF00567.24	6e-131	3	4
ENSP00000251864	TUDOR	PF00567.24	6e-131	4	4
ENSP00000358286	TUDOR	PF00567.24	1.4e-130	1	4
ENSP00000358286	TUDOR	PF00567.24	1.4e-130	2	4
ENSP00000358286	TUDOR	PF00567.24	1.4e-130	3	4
ENSP00000358286	TUDOR	PF00567.24	1.4e-130	4	4
ENSP00000358288	TUDOR	PF00567.24	1.5e-130	1	4
ENSP00000358288	TUDOR	PF00567.24	1.5e-130	2	4
ENSP00000358288	TUDOR	PF00567.24	1.5e-130	3	4
ENSP00000358288	TUDOR	PF00567.24	1.5e-130	4	4

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000369280	TDRD1-202	4062	XM_011539963	ENSP00000358286	1104 (aa)	XP_011538265	H9KV62
ENST00000251864	TDRD1-201	4510	XM_005269978	ENSP00000251864	1189 (aa)	XP_005270035	Q9BXT4
ENST00000369282	TDRD1-203	3705	XM_005269979	ENSP00000358288	1113 (aa)	XP_005270036	H9KV63

Gene Model

Click here to download ENSG00000095627's gene model file

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000095627	rs10160173	10	114215306	?	Adolescent idiopathic scoliosis	30019117			EFO_0005423

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000095627's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000095627	TDRD1	70	35.263	ENSG00000132972	RNF17	99	35.263

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000095627	TDRD1	88	34.839	ENSAPOG00000023199	tdrd1	90	34.940	Acanthochromis_polyacanthus
ENSG00000095627	TDRD1	100	86.957	ENSAMEG00000015182	TDRD1	99	86.957	Ailuropoda_melanoleuca
ENSG00000095627	TDRD1	87	34.708	ENSACIG00000010576	tdrd1	90	34.708	Amphilophus_citrinellus
ENSG00000095627	TDRD1	86	33.684	ENSAOCG00000007059	tdrd1	89	33.780	Amphiprion_ocellaris
ENSG00000095627	TDRD1	86	35.419	ENSAPEG00000017049	tdrd1	88	35.419	Amphiprion_percula
ENSG00000095627	TDRD1	86	35.070	ENSATEG00000021627	tdrd1	91	33.703	Anabas_testudineus
ENSG00000095627	TDRD1	87	67.568	ENSAPLG00000012609	TDRD1	98	67.568	Anas_platyrhynchos
ENSG00000095627	TDRD1	98	39.492	ENSACAG00000009854	TDRD1	99	39.492	Anolis_carolinensis
ENSG00000095627	TDRD1	99	92.453	ENSANAG00000035710	TDRD1	99	92.453	Aotus_nancymaae
ENSG00000095627	TDRD1	87	34.527	ENSACLG00000014107	tdrd1	88	33.364	Astatotilapia_calliptera
ENSG00000095627	TDRD1	84	35.360	ENSAMXG00000015146	tdrd1	83	35.360	Astyanax_mexicanus
ENSG00000095627	TDRD1	100	86.957	ENSBTAG00000006855	TDRD1	99	86.957	Bos_taurus
ENSG00000095627	TDRD1	98	95.556	ENSCJAG00000019270	TDRD1	99	95.556	Callithrix_jacchus
ENSG00000095627	TDRD1	99	86.957	ENSCAFG00000011266	TDRD1	100	86.957	Canis_familiaris
ENSG00000095627	TDRD1	100	86.957	ENSCAFG00020012373	TDRD1	100	88.889	Canis_lupus_dingo
ENSG00000095627	TDRD1	99	88.095	ENSCHIG00000012766	TDRD1	99	88.095	Capra_hircus
ENSG00000095627	TDRD1	100	90.698	ENSTSYG00000004935	TDRD1	96	90.698	Carlito_syrichta
ENSG00000095627	TDRD1	99	80.000	ENSCPOG00000004190	TDRD1	99	80.000	Cavia_porcellus
ENSG00000095627	TDRD1	99	97.778	ENSCCAG00000027375	TDRD1	100	97.778	Cebus_capucinus
ENSG00000095627	TDRD1	100	98.182	ENSCATG00000035999	TDRD1	100	98.182	Cercocebus_atys
ENSG00000095627	TDRD1	100	80.435	ENSCLAG00000003935	TDRD1	98	80.435	Chinchilla_lanigera
ENSG00000095627	TDRD1	100	97.778	ENSCSAG00000005071	TDRD1	98	97.778	Chlorocebus_sabaeus
ENSG00000095627	TDRD1	99	90.909	ENSCHOG00000001690	TDRD1	93	90.909	Choloepus_hoffmanni
ENSG00000095627	TDRD1	97	52.517	ENSCPBG00000003780	TDRD1	99	52.517	Chrysemys_picta_bellii
ENSG00000095627	TDRD1	99	94.617	ENSCANG00000035172	TDRD1	100	94.617	Colobus_angolensis_palliatus
ENSG00000095627	TDRD1	97	73.119	ENSCGRG00001004632	Tdrd1	100	73.119	Cricetulus_griseus_chok1gshd
ENSG00000095627	TDRD1	99	77.551	ENSCGRG00000004981	Tdrd1	99	77.551	Cricetulus_griseus_crigri
ENSG00000095627	TDRD1	84	34.156	ENSCSEG00000006983	tdrd1	91	32.892	Cynoglossus_semilaevis
ENSG00000095627	TDRD1	80	33.589	ENSCVAG00000020980	tdrd1	92	33.589	Cyprinodon_variegatus
ENSG00000095627	TDRD1	81	38.361	ENSDARG00000007465	tdrd1	89	37.809	Danio_rerio
ENSG00000095627	TDRD1	99	84.783	ENSDNOG00000012114	TDRD1	98	84.783	Dasypus_novemcinctus
ENSG00000095627	TDRD1	99	76.596	ENSDORG00000009986	Tdrd1	99	76.596	Dipodomys_ordii
ENSG00000095627	TDRD1	88	70.588	ENSETEG00000020143	TDRD1	87	70.588	Echinops_telfairi
ENSG00000095627	TDRD1	100	85.106	ENSEASG00005014802	TDRD1	100	86.667	Equus_asinus_asinus
ENSG00000095627	TDRD1	100	84.783	ENSECAG00000009748	TDRD1	96	84.783	Equus_caballus
ENSG00000095627	TDRD1	100	75.231	ENSEEUG00000010076	TDRD1	100	75.231	Erinaceus_europaeus
ENSG00000095627	TDRD1	86	33.366	ENSELUG00000024364	tdrd1	88	33.366	Esox_lucius
ENSG00000095627	TDRD1	99	86.667	ENSFCAG00000000632	TDRD1	98	86.667	Felis_catus
ENSG00000095627	TDRD1	76	61.538	ENSFALG00000002237	TDRD1	91	61.538	Ficedula_albicollis
ENSG00000095627	TDRD1	99	82.979	ENSFDAG00000013225	TDRD1	99	82.979	Fukomys_damarensis
ENSG00000095627	TDRD1	82	30.946	ENSFHEG00000009203	tdrd1	91	30.649	Fundulus_heteroclitus
ENSG00000095627	TDRD1	73	37.963	ENSGMOG00000016797	-	69	37.963	Gadus_morhua
ENSG00000095627	TDRD1	91	44.667	ENSGALG00000046180	TDRD1	99	44.667	Gallus_gallus
ENSG00000095627	TDRD1	84	34.683	ENSGAFG00000002668	tdrd1	92	34.303	Gambusia_affinis
ENSG00000095627	TDRD1	79	36.054	ENSGACG00000006590	tdrd1	99	36.054	Gasterosteus_aculeatus
ENSG00000095627	TDRD1	100	100.000	ENSGGOG00000004250	TDRD1	100	100.000	Gorilla_gorilla
ENSG00000095627	TDRD1	85	34.420	ENSHBUG00000005216	tdrd1	86	33.333	Haplochromis_burtoni
ENSG00000095627	TDRD1	99	85.106	ENSHGLG00000010877	TDRD1	98	85.106	Heterocephalus_glaber_female
ENSG00000095627	TDRD1	95	77.113	ENSHGLG00100013857	TDRD1	99	77.281	Heterocephalus_glaber_male
ENSG00000095627	TDRD1	88	30.703	ENSHCOG00000002840	tdrd1	91	30.826	Hippocampus_comes
ENSG00000095627	TDRD1	82	35.814	ENSIPUG00000017232	tdrd1	90	36.030	Ictalurus_punctatus
ENSG00000095627	TDRD1	100	89.362	ENSSTOG00000003221	TDRD1	100	91.111	Ictidomys_tridecemlineatus
ENSG00000095627	TDRD1	98	75.554	ENSJJAG00000014720	Tdrd1	99	75.809	Jaculus_jaculus
ENSG00000095627	TDRD1	81	34.926	ENSKMAG00000018558	tdrd1	96	34.926	Kryptolebias_marmoratus
ENSG00000095627	TDRD1	87	35.135	ENSLBEG00000004161	tdrd1	86	35.135	Labrus_bergylta
ENSG00000095627	TDRD1	96	43.497	ENSLACG00000011559	TDRD1	100	43.497	Latimeria_chalumnae
ENSG00000095627	TDRD1	86	36.493	ENSLOCG00000012030	tdrd1	100	38.255	Lepisosteus_oculatus
ENSG00000095627	TDRD1	78	79.333	ENSLAFG00000011575	TDRD1	99	79.333	Loxodonta_africana
ENSG00000095627	TDRD1	100	98.182	ENSMFAG00000043487	TDRD1	100	98.182	Macaca_fascicularis
ENSG00000095627	TDRD1	100	98.182	ENSMMUG00000022517	TDRD1	100	98.182	Macaca_mulatta
ENSG00000095627	TDRD1	100	98.182	ENSMNEG00000031108	TDRD1	100	98.182	Macaca_nemestrina
ENSG00000095627	TDRD1	100	98.182	ENSMLEG00000032281	TDRD1	100	98.182	Mandrillus_leucophaeus
ENSG00000095627	TDRD1	85	34.241	ENSMAMG00000015287	tdrd1	91	35.325	Mastacembelus_armatus
ENSG00000095627	TDRD1	87	34.757	ENSMZEG00005025315	tdrd1	89	33.577	Maylandia_zebra
ENSG00000095627	TDRD1	87	56.410	ENSMGAG00000011067	TDRD1	99	56.410	Meleagris_gallopavo
ENSG00000095627	TDRD1	95	67.045	ENSMAUG00000012164	Tdrd1	97	67.045	Mesocricetus_auratus
ENSG00000095627	TDRD1	100	89.362	ENSMICG00000016190	TDRD1	99	89.362	Microcebus_murinus
ENSG00000095627	TDRD1	99	71.814	ENSMOCG00000022360	Tdrd1	99	72.133	Microtus_ochrogaster
ENSG00000095627	TDRD1	85	35.082	ENSMMOG00000014068	tdrd1	88	35.353	Mola_mola
ENSG00000095627	TDRD1	99	78.049	ENSMODG00000009788	TDRD1	99	78.049	Monodelphis_domestica
ENSG00000095627	TDRD1	87	34.692	ENSMALG00000022115	tdrd1	90	35.312	Monopterus_albus
ENSG00000095627	TDRD1	99	75.510	MGP_CAROLIEiJ_G0023095	Tdrd1	100	75.510	Mus_caroli
ENSG00000095627	TDRD1	99	71.429	ENSMUSG00000025081	Tdrd1	99	71.806	Mus_musculus
ENSG00000095627	TDRD1	98	72.658	MGP_PahariEiJ_G0014583	Tdrd1	99	72.658	Mus_pahari
ENSG00000095627	TDRD1	99	75.510	MGP_SPRETEiJ_G0024016	Tdrd1	100	75.510	Mus_spretus
ENSG00000095627	TDRD1	100	91.304	ENSMPUG00000001987	TDRD1	99	91.304	Mustela_putorius_furo
ENSG00000095627	TDRD1	99	78.723	ENSNGAG00000015231	Tdrd1	100	78.723	Nannospalax_galili
ENSG00000095627	TDRD1	82	33.696	ENSNBRG00000017920	tdrd1	85	33.696	Neolamprologus_brichardi
ENSG00000095627	TDRD1	100	94.545	ENSNLEG00000016228	TDRD1	100	94.545	Nomascus_leucogenys
ENSG00000095627	TDRD1	99	84.615	ENSMEUG00000007717	TDRD1	99	84.615	Notamacropus_eugenii
ENSG00000095627	TDRD1	99	80.435	ENSOPRG00000009180	TDRD1	99	80.435	Ochotona_princeps
ENSG00000095627	TDRD1	99	82.979	ENSODEG00000011965	TDRD1	97	82.979	Octodon_degus
ENSG00000095627	TDRD1	87	34.990	ENSONIG00000016382	tdrd1	88	33.109	Oreochromis_niloticus
ENSG00000095627	TDRD1	98	60.870	ENSOANG00000001562	TDRD1	99	60.870	Ornithorhynchus_anatinus
ENSG00000095627	TDRD1	98	82.979	ENSOCUG00000025327	TDRD1	99	82.979	Oryctolagus_cuniculus
ENSG00000095627	TDRD1	82	35.837	ENSORLG00000004833	tdrd1	86	34.853	Oryzias_latipes
ENSG00000095627	TDRD1	82	35.944	ENSORLG00020019231	tdrd1	97	34.067	Oryzias_latipes_hni
ENSG00000095627	TDRD1	82	35.845	ENSORLG00015017184	tdrd1	85	34.858	Oryzias_latipes_hsok
ENSG00000095627	TDRD1	81	36.022	ENSOMEG00000023637	tdrd1	82	35.127	Oryzias_melastigma
ENSG00000095627	TDRD1	100	89.362	ENSOGAG00000001370	TDRD1	100	89.362	Otolemur_garnettii
ENSG00000095627	TDRD1	99	81.633	ENSOARG00000014200	-	99	81.633	Ovis_aries
ENSG00000095627	TDRD1	100	100.000	ENSPPAG00000041621	TDRD1	100	100.000	Pan_paniscus
ENSG00000095627	TDRD1	99	86.667	ENSPPRG00000000191	TDRD1	98	86.667	Panthera_pardus
ENSG00000095627	TDRD1	100	86.667	ENSPTIG00000010264	TDRD1	100	86.364	Panthera_tigris_altaica
ENSG00000095627	TDRD1	100	100.000	ENSPTRG00000002958	TDRD1	100	100.000	Pan_troglodytes
ENSG00000095627	TDRD1	100	98.182	ENSPANG00000020752	TDRD1	100	98.182	Papio_anubis
ENSG00000095627	TDRD1	84	35.693	ENSPKIG00000010586	tdrd1	91	35.693	Paramormyrops_kingsleyae
ENSG00000095627	TDRD1	99	66.667	ENSPSIG00000014655	TDRD1	99	66.667	Pelodiscus_sinensis
ENSG00000095627	TDRD1	81	32.327	ENSPMGG00000018890	tdrd1	100	32.120	Periophthalmus_magnuspinnatus
ENSG00000095627	TDRD1	99	76.087	ENSPEMG00000004582	Tdrd1	99	76.087	Peromyscus_maniculatus_bairdii
ENSG00000095627	TDRD1	72	30.833	ENSPMAG00000004416	-	99	30.833	Petromyzon_marinus
ENSG00000095627	TDRD1	99	78.571	ENSPCIG00000009739	TDRD1	99	78.571	Phascolarctos_cinereus
ENSG00000095627	TDRD1	79	34.739	ENSPFOG00000002145	tdrd1	89	33.951	Poecilia_formosa
ENSG00000095627	TDRD1	87	34.043	ENSPLAG00000010241	tdrd1	89	33.270	Poecilia_latipinna
ENSG00000095627	TDRD1	87	34.277	ENSPMEG00000021893	tdrd1	87	34.277	Poecilia_mexicana
ENSG00000095627	TDRD1	87	33.871	ENSPREG00000022663	tdrd1	91	33.871	Poecilia_reticulata
ENSG00000095627	TDRD1	100	100.000	ENSPPYG00000002671	TDRD1	99	100.000	Pongo_abelii
ENSG00000095627	TDRD1	96	71.813	ENSPCAG00000006692	TDRD1	97	67.795	Procavia_capensis
ENSG00000095627	TDRD1	99	89.130	ENSPCOG00000026619	TDRD1	99	87.273	Propithecus_coquereli
ENSG00000095627	TDRD1	99	78.040	ENSPVAG00000003055	TDRD1	99	78.867	Pteropus_vampyrus
ENSG00000095627	TDRD1	82	33.465	ENSPNYG00000001706	tdrd1	84	33.465	Pundamilia_nyererei
ENSG00000095627	TDRD1	81	38.362	ENSPNAG00000005831	tdrd1	94	35.936	Pygocentrus_nattereri
ENSG00000095627	TDRD1	99	75.510	ENSRNOG00000017064	Tdrd1	99	75.510	Rattus_norvegicus
ENSG00000095627	TDRD1	100	91.855	ENSRBIG00000029668	TDRD1	98	94.811	Rhinopithecus_bieti
ENSG00000095627	TDRD1	100	94.958	ENSRROG00000043379	TDRD1	100	94.958	Rhinopithecus_roxellana
ENSG00000095627	TDRD1	99	92.453	ENSSBOG00000023561	TDRD1	99	92.453	Saimiri_boliviensis_boliviensis
ENSG00000095627	TDRD1	99	82.927	ENSSHAG00000014311	TDRD1	99	82.927	Sarcophilus_harrisii
ENSG00000095627	TDRD1	81	36.454	ENSSFOG00015022020	tdrd1	91	35.900	Scleropages_formosus
ENSG00000095627	TDRD1	82	35.244	ENSSMAG00000019271	tdrd1	88	34.638	Scophthalmus_maximus
ENSG00000095627	TDRD1	82	34.627	ENSSDUG00000022012	tdrd1	89	33.664	Seriola_dumerili
ENSG00000095627	TDRD1	82	34.177	ENSSLDG00000006423	tdrd1	89	33.234	Seriola_lalandi_dorsalis
ENSG00000095627	TDRD1	99	82.609	ENSSARG00000008828	TDRD1	83	82.609	Sorex_araneus
ENSG00000095627	TDRD1	92	49.182	ENSSPUG00000005015	TDRD1	99	49.182	Sphenodon_punctatus
ENSG00000095627	TDRD1	86	33.702	ENSSPAG00000018805	tdrd1	89	32.574	Stegastes_partitus
ENSG00000095627	TDRD1	99	85.714	ENSSSCG00000021075	TDRD1	99	85.714	Sus_scrofa
ENSG00000095627	TDRD1	75	58.974	ENSTGUG00000010905	TDRD1	98	58.974	Taeniopygia_guttata
ENSG00000095627	TDRD1	82	34.747	ENSTRUG00000012142	tdrd1	99	34.120	Takifugu_rubripes
ENSG00000095627	TDRD1	80	46.377	ENSTNIG00000018898	tdrd1	100	34.988	Tetraodon_nigroviridis
ENSG00000095627	TDRD1	76	86.957	ENSTBEG00000014978	-	55	86.957	Tupaia_belangeri
ENSG00000095627	TDRD1	100	89.130	ENSTBEG00000014417	-	99	89.130	Tupaia_belangeri
ENSG00000095627	TDRD1	100	84.783	ENSTTRG00000010147	TDRD1	98	85.417	Tursiops_truncatus
ENSG00000095627	TDRD1	100	91.304	ENSUAMG00000009025	TDRD1	100	91.111	Ursus_americanus
ENSG00000095627	TDRD1	100	91.304	ENSUMAG00000000705	TDRD1	100	91.111	Ursus_maritimus
ENSG00000095627	TDRD1	100	89.130	ENSVPAG00000004000	TDRD1	98	89.130	Vicugna_pacos
ENSG00000095627	TDRD1	100	89.130	ENSVVUG00000009750	TDRD1	100	89.130	Vulpes_vulpes
ENSG00000095627	TDRD1	71	36.100	ENSXCOG00000006412	tdrd1	97	36.100	Xiphophorus_couchianus
ENSG00000095627	TDRD1	84	34.881	ENSXMAG00000008104	tdrd1	97	34.213	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0005737	cytoplasm	-	ISS	Component
GO:0007275	multicellular organism development	-	IEA	Process
GO:0007281	germ cell development	-	ISS	Process
GO:0007283	spermatogenesis	-	ISS	Process
GO:0031047	gene silencing by RNA	-	ISS	Process
GO:0033391	chromatoid body	-	IEA	Component
GO:0034587	piRNA metabolic process	-	ISS	Process
GO:0043046	DNA methylation involved in gamete generation	-	ISS	Process
GO:0043186	P granule	-	ISS	Component
GO:0046872	metal ion binding	-	IEA	Function
GO:0051321	meiotic cell cycle	-	IEA	Process
GO:0071546	pi-body	-	ISS	Component

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
23319146	Identification of TDRD1 as a direct target gene of ERG in primary prostate cancer.	Int J Cancer	2013 Jul 15	Boormans JL	doi: 10.1002/ijc.28025
23555854	ERG induces epigenetic activation of Tudor domain-containing protein 1 (TDRD1) in ERG rearrangement-positive prostate cancer.	PLoS One	2013	Kacprzyk LA	doi: 10.1371/journal.pone.0059976

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr10	114221428	Missense_Mutation	rs765732209	E948K	0.14	TUDOR
BLCA	chr10	114203427	Missense_Mutation	rs138005760	V281M	0.42
BLCA	chr10	114220652	Missense_Mutation	novel	R860T	0.28
BLCA	chr10	114226132	Missense_Mutation	NA	E1031K	0.28	TUDOR
BLCA	chr10	114188107	Silent	NA	I92I	0.18
BLCA	chr10	114210702	Silent	novel	H502H	0.1
BLCA	chr10	114204835	Silent	novel	V413V	0.29
BLCA	chr10	114210966	Splice_Region	novel	S553S	0.39
BLCA	chr10	114203099	Missense_Mutation	novel	E242K	0.35
BLCA	chr10	114218560	Nonsense_Mutation	NA	Q824*	0.2
BLCA	chr10	114202251	Missense_Mutation	NA	E217K	0.28
BLCA	chr10	114187831	5'UTR	novel		0.16
BLCA	chr10	114203128	Missense_Mutation	rs770791214	M251I	0.24
BRCA	chr10	114214079	Missense_Mutation	novel	P726L	0.03
BRCA	chr10	114221363	Missense_Mutation	NA	S926C	0.2
BRCA	chr10	114203440	Missense_Mutation	novel	S285F	0.06
BRCA	chr10	114214098	Silent	NA	H732H	0.33
BRCA	chr10	114220595	Missense_Mutation	novel	S841Y	0.35
BRCA	chr10	114227160	Silent	NA	V1088V	0.35
BRCA	chr10	114227099	Missense_Mutation	NA	S1068C	0.33
BRCA	chr10	114204738	Missense_Mutation	NA	V381A	0.27
BRCA	chr10	114220577	Missense_Mutation	novel	S835C	0.19
BRCA	chr10	114213525	Missense_Mutation	novel	G671C	0.06
BRCA	chr10	114228166	Intron	novel		0.28
BRCA	chr10	114210726	Missense_Mutation	NA	F510L	0.11
BRCA	chr10	114218432	Missense_Mutation	NA	R781H	0.11
BRCA	chr10	114220754	Missense_Mutation	novel	V894A	0.07
BRCA	chr10	114214097	Nonsense_Mutation	novel	V733*	0.04
CESC	chr10	114228035	Splice_Region	rs745846290		0.36
CESC	chr10	114214039	Missense_Mutation	NA	D713N	0.42
CESC	chr10	114211966	Silent	novel	L587L	0.22
CESC	chr10	114187876	Frame_Shift_Del	novel	*E16Kfs7**	0.41
CESC	chr10	114187877	Missense_Mutation	NA	E16K	0.41
CESC	chr10	114199172	Splice_Site	novel	X129_splice	0.1
CESC	chr10	114187988	Missense_Mutation	novel	F53V	0.37
CESC	chr10	114199309	Missense_Mutation	novel	G174D	0.29
CESC	chr10	114210749	Splice_Site	novel	X518_splice	0.4
CESC	chr10	114214116	Splice_Site	NA	X738_splice	0.45
CESC	chr10	114231546	3'UTR	novel		0.24
CESC	chr10	114227233	Missense_Mutation	NA	D1113H	0.19
CESC	chr10	114213492	Missense_Mutation	NA	H660D	0.16
CESC	chr10	114204173	Missense_Mutation	novel	R361T	0.13
CESC	chr10	114187916	Missense_Mutation	NA	E29Q	0.11
CESC	chr10	114213516	Missense_Mutation	NA	L668I	0.55
COAD	chr10	114188030	Missense_Mutation	novel	F67V	0.27
COAD	chr10	114204085	Missense_Mutation	novel	A332S	0.27
COAD	chr10	114187851	Missense_Mutation	novel	F7C	0.1
COAD	chr10	114213444	Silent	novel	L644L	0.17
COAD	chr10	114217615	Missense_Mutation	novel	F761L	0.29
COAD	chr10	114227217	Silent	novel	G1107G	0.05
COAD	chr10	114202273	Missense_Mutation	novel	T224I	0.07
COAD	chr10	114199204	Frame_Shift_Ins	NA	*L142Tfs13**	0.26
COAD	chr10	114227121	Missense_Mutation	novel	L1075F	0.5
COAD	chr10	114228177	Intron	novel		0.07
COAD	chr10	114202292	Silent	novel	N230N	0.22
COAD	chr10	114190979	Missense_Mutation	novel	P115Q	0.23
COAD	chr10	114203178	Splice_Site	novel	X267_splice	0.09
COAD	chr10	114213579	Nonsense_Mutation	NA	E689*	0.17
COAD	chr10	114214084	Missense_Mutation	NA	E728K	0.27
COAD	chr10	114218494	In_Frame_Ins	novel	N802delinsTFPFYRH	0.05
ESCA	chr10	114227121	Frame_Shift_Del	novel	*N1077Ifs4**	0.4
ESCA	chr10	114227129	Missense_Mutation	novel	F1078C	0.35
ESCA	chr10	114221410	Missense_Mutation	rs376481564	I942V	0.3	TUDOR
ESCA	chr10	114204128	Missense_Mutation	novel	V346A	0.45
GBM	chr10	114213524	Silent	novel	A670A	0.1
GBM	chr10	114220743	Missense_Mutation	novel	D890E	0.31
GBM	chr10	114204881	Missense_Mutation	novel	L429M	0.15
GBM	chr10	114210607	Missense_Mutation	novel	T471A	0.37
GBM	chr10	114211917	Missense_Mutation	novel	S571Y	0.17
GBM	chr10	114213375	Missense_Mutation	novel	P621S	0.43
GBM	chr10	114228038	Missense_Mutation	rs766881742	V1151I	0.23
GBM	chr10	114228152	Intron	rs759591914		0.21
GBM	chr10	114201432	Nonsense_Mutation	novel	C184*	0.06
GBM	chr10	114213508	Missense_Mutation	novel	K665I	0.31
GBM	chr10	114203460	Missense_Mutation	novel	M292L	0.1
GBM	chr10	114218484	Silent	novel	V798V	0.2
GBM	chr10	114227144	Missense_Mutation	novel	N1083I	0.05
HNSC	chr10	114210714	Silent	novel	P506P	0.46
HNSC	chr10	114187987	Silent	novel	N52N	0.12
HNSC	chr10	114227283	Missense_Mutation	novel	Q1129H	0.21
HNSC	chr10	114213371	Nonsense_Mutation	novel	W619*	0.33
HNSC	chr10	114202286	Silent	novel	E228E	0.32
HNSC	chr10	114214001	Missense_Mutation	novel	V700A	0.24
HNSC	chr10	114211928	Missense_Mutation	novel	G575R	0.29
HNSC	chr10	114210922	Missense_Mutation	novel	D539N	0.24
HNSC	chr10	114226151	Missense_Mutation	novel	R1037K	0.21	TUDOR
HNSC	chr10	114218485	Missense_Mutation	novel	D799Y	0.21
HNSC	chr10	114220620	Silent	novel	Q849Q	0.05
HNSC	chr10	114218499	Silent	rs748563814	I803I	0.16
HNSC	chr10	114226114	Missense_Mutation	novel	A1025P	0.15	TUDOR
KIRC	chr10	114213344	Splice_Site	NA	X611_splice	0.14
KIRP	chr10	114188045	Nonsense_Mutation	novel	Q72*	0.46
KIRP	chr10	114204852	Missense_Mutation	novel	E419V	0.39
KIRP	chr10	114218472	Missense_Mutation	NA	K794N	0.07
KIRP	chr10	114187871	In_Frame_Del	novel	N14_L15del	0.43
LAML	chr10	114201421	Missense_Mutation	novel	C181R	0.37
LAML	chr10	114227279	Missense_Mutation	novel	R1128T	0.23
LGG	chr10	114202284	Missense_Mutation	novel	E228K	0.39
LGG	chr10	114204781	Silent	novel	C395C	0.71
LIHC	chr10	114228335	Intron	novel		0.4
LIHC	chr10	114227240	Missense_Mutation	NA	L1115R	0.33
LIHC	chr10	114217650	Splice_Site	novel	X775_splice	0.13
LIHC	chr10	114206281	Nonsense_Mutation	novel	Y445*	0.72
LIHC	chr10	114226178	Missense_Mutation	NA	L1046P	0.38	TUDOR
LIHC	chr10	114188048	Missense_Mutation	NA	T73S	0.85
LIHC	chr10	114227916	Missense_Mutation	NA	M1137T	0.24
LIHC	chr10	114199270	Missense_Mutation	NA	L161S	0.53
LUAD	chr10	114226067	Missense_Mutation	novel	R1009H	0.07	TUDOR
LUAD	chr10	114210881	Missense_Mutation	rs753980626	A525E	0.38
LUAD	chr10	114203427	Missense_Mutation	novel	V281L	0.18
LUAD	chr10	114203567	Splice_Region	novel	Q327Q	0.3
LUAD	chr10	114210877	Nonsense_Mutation	NA	Q524*	0.18
LUAD	chr10	114217628	Missense_Mutation	NA	G766R	0.29
LUAD	chr10	114211878	Nonsense_Mutation	NA	W558*	0.13
LUAD	chr10	114213446	Missense_Mutation	novel	L644F	0.17
LUAD	chr10	114227156	Missense_Mutation	NA	S1087F	0.36
LUAD	chr10	114227921	Missense_Mutation	NA	R1139G	0.11
LUAD	chr10	114213485	Missense_Mutation	NA	E657D	0.39
LUAD	chr10	114222681	Silent	rs767859168	D995D	0.22
LUAD	chr10	114204199	Missense_Mutation	novel	D370Y	0.4
LUAD	chr10	114222671	Missense_Mutation	novel	R992T	0.21	TUDOR
LUAD	chr10	114190987	Missense_Mutation	NA	E118K	0.36
LUAD	chr10	114213425	Silent	novel	T637T	0.18
LUAD	chr10	114204109	Nonsense_Mutation	novel	Q340*	0.14
LUSC	chr10	114218555	Missense_Mutation	NA	P822L	0.18
LUSC	chr10	114218501	Missense_Mutation	novel	E804G	0.09
LUSC	chr10	114221463	Silent	rs144170696	P959P	0.12
LUSC	chr10	114201481	Missense_Mutation	NA	A201S	0.08
LUSC	chr10	114227199	Missense_Mutation	NA	E1101D	0.26
LUSC	chr10	114227287	Missense_Mutation	novel	A1131S	0.4
LUSC	chr10	114210679	Missense_Mutation	novel	E495K	0.14
LUSC	chr10	114214022	Missense_Mutation	NA	W707L	0.38
LUSC	chr10	114211991	Nonsense_Mutation	novel	K596*	0.34
LUSC	chr10	114188132	Missense_Mutation	NA	G101R	0.48
LUSC	chr10	114188134	Silent	NA	G101G	0.47
LUSC	chr10	114204762	Missense_Mutation	novel	G389E	0.15
LUSC	chr10	114210951	Silent	NA	C548C	0.16
LUSC	chr10	114202251	Missense_Mutation	novel	E217Q	0.07
LUSC	chr10	114231546	3'UTR	novel		0.44
LUSC	chr10	114203404	Missense_Mutation	NA	F273C	0.31
LUSC	chr10	114220620	Missense_Mutation	NA	Q849H	0.2
MESO	chr10	114231628	3'UTR	rs576030952		0.6
OV	chr10	114202273	Missense_Mutation	novel	T224I	0.08
OV	chr10	114199226	Silent	NA	V146V	0.31
OV	chr10	114227249	Missense_Mutation	novel	F1118Y	0.27
OV	chr10	114221385	Silent	novel	T933T	0.06
OV	chr10	114227249	Frame_Shift_Ins	novel	*F1118Lfs22**	0.17
OV	chr10	114218569	Missense_Mutation	NA	R827W	0.4
OV	chr10	114203095	Silent	novel	T240T	0.15
OV	chr10	114202273	Missense_Mutation	novel	T224I	0.17
OV	chr10	114220844	Splice_Site	NA	X924_splice	0.41
OV	chr10	114188018	Missense_Mutation	novel	K63E	0.04
OV	chr10	114220648	Missense_Mutation	NA	A859P	0.78
PAAD	chr10	114210922	Missense_Mutation	novel	D539Y	0.26
PAAD	chr10	114226137	Silent	novel	T1032T	0.2
PRAD	chr10	114211931	Missense_Mutation	NA	Y576H	0.07
PRAD	chr10	114222681	Silent	rs767859168	D995D	0.41
READ	chr10	114228142	Intron	novel		0.18
READ	chr10	114226181	Missense_Mutation	rs576653939	A1047V	0.35	TUDOR
READ	chr10	114188146	Frame_Shift_Ins	novel	*P107Afs12**	0.14
READ	chr10	114203162	Missense_Mutation	novel	T263A	0.2
READ	chr10	114203487	Nonsense_Mutation	novel	E301*	0.44
READ	chr10	114228152	Intron	rs759591914		0.5
READ	chr10	114217552	Missense_Mutation	NA	K740N	0.46
READ	chr10	114220825	Missense_Mutation	NA	H918N	0.32
SARC	chr10	114204836	Missense_Mutation	novel	D414N	0.45
SARC	chr10	114203090	Missense_Mutation	novel	V239I	0.39
SKCM	chr10	114203508	Missense_Mutation	NA	E308K	0.97
SKCM	chr10	114203167	Missense_Mutation	NA	M264I	0.2
SKCM	chr10	114213995	Missense_Mutation	NA	G698E	0.35
SKCM	chr10	114211958	Missense_Mutation	NA	L585F	0.29
SKCM	chr10	114226186	Missense_Mutation	NA	P1049S	0.24	TUDOR
SKCM	chr10	114220695	Silent	rs748452799	T874T	0.28
SKCM	chr10	114228038	Missense_Mutation	novel	V1151F	0.11
SKCM	chr10	114213537	Missense_Mutation	novel	G675R	0.42
SKCM	chr10	114231494	Missense_Mutation	novel	S1183A	0.48
SKCM	chr10	114206315	Missense_Mutation	NA	E457K	0.37
SKCM	chr10	114188006	Missense_Mutation	NA	E59K	0.31
SKCM	chr10	114210884	Missense_Mutation	novel	S526F	0.42
SKCM	chr10	114218524	Nonsense_Mutation	NA	R812*	0.28
SKCM	chr10	114204173	Missense_Mutation	NA	R361K	0.23
SKCM	chr10	114213370	Nonsense_Mutation	NA	W619*	0.17
SKCM	chr10	114227079	Missense_Mutation	NA	M1061I	0.23
SKCM	chr10	114221385	Silent	rs199767512	T933T	0.49
SKCM	chr10	114210935	Missense_Mutation	NA	A543V	0.97
SKCM	chr10	114188132	Missense_Mutation	NA	G101R	0.37
SKCM	chr10	114218446	Missense_Mutation	novel	E786K	0.51
SKCM	chr10	114211957	Silent	NA	I584I	0.33
SKCM	chr10	114188132	Missense_Mutation	NA	G101R	0.22
SKCM	chr10	114210943	Missense_Mutation	NA	D546N	0.09
SKCM	chr10	114199302	Missense_Mutation	novel	R172C	0.29
SKCM	chr10	114222676	Missense_Mutation	novel	G994R	0.33	TUDOR
SKCM	chr10	114214007	Missense_Mutation	NA	P702L	0.69
SKCM	chr10	114202251	Missense_Mutation	NA	E217K	0.43
SKCM	chr10	114213457	Missense_Mutation	rs780473726	S648F	0.45
SKCM	chr10	114227121	Frame_Shift_Del	novel	*N1077Ifs4**	0.5
SKCM	chr10	114211957	Silent	NA	I584I	0.23
SKCM	chr10	114199234	Missense_Mutation	NA	S149F	0.29
SKCM	chr10	114226144	Missense_Mutation	rs141065182	L1035F	0.29	TUDOR
SKCM	chr10	114210650	Missense_Mutation	NA	P485L	0.83
SKCM	chr10	114231585	3'UTR	novel		0.29
SKCM	chr10	114203535	Missense_Mutation	NA	E317K	0.22
SKCM	chr10	114204760	Silent	NA	E388E	0.58
SKCM	chr10	114188140	Silent	NA	R103R	0.27
SKCM	chr10	114228084	Missense_Mutation	NA	T1166I	0.8
SKCM	chr10	114213364	Missense_Mutation	NA	G617E	0.69
SKCM	chr10	114187985	Missense_Mutation	NA	N52D	0.06
SKCM	chr10	114226186	Missense_Mutation	NA	P1049S	0.34	TUDOR
SKCM	chr10	114211944	Missense_Mutation	rs267602371	G580E	0.68
SKCM	chr10	114201413	Missense_Mutation	NA	S178L	0.22
SKCM	chr10	114213395	Missense_Mutation	novel	M627I	0.3
SKCM	chr10	114204173	Missense_Mutation	NA	R361K	0.52
SKCM	chr10	114210884	Missense_Mutation	novel	S526F	0.6
SKCM	chr10	114226066	Missense_Mutation	NA	R1009C	0.17	TUDOR
SKCM	chr10	114218431	Missense_Mutation	novel	R781C	0.26
SKCM	chr10	114220696	Missense_Mutation	rs770914554	D875N	0.56
STAD	chr10	114217551	Missense_Mutation	novel	K740T	0.15
STAD	chr10	114227121	Frame_Shift_Del	novel	*N1077Ifs4**	0.22
STAD	chr10	114210747	Splice_Region	NA	G517G	0.13
STAD	chr10	114202277	Silent	rs776710570	K225K	0.39
STAD	chr10	114212016	Missense_Mutation	novel	A604V	0.1
STAD	chr10	114211968	Missense_Mutation	NA	M588T	0.31
STAD	chr10	114203552	Missense_Mutation	NA	K322N	0.05
STAD	chr10	114221399	Missense_Mutation	NA	V938A	0.25	TUDOR
STAD	chr10	114199276	Missense_Mutation	NA	P163L	0.22
STAD	chr10	114199295	Silent	NA	T169T	0.29
STAD	chr10	114206275	Missense_Mutation	NA	M443I	0.08
STAD	chr10	114227259	Frame_Shift_Del	NA	*N1123Tfs10**	0.27
STAD	chr10	114228110	Frame_Shift_Del	novel	*K1176Nfs3**	0.29
STAD	chr10	114210924	Frame_Shift_Del	novel	*Y541Ifs37**	0.36
STAD	chr10	114213406	Missense_Mutation	NA	V631A	0.25
STAD	chr10	114210922	Missense_Mutation	novel	D539Y	0.81
STAD	chr10	114188140	Frame_Shift_Ins	novel	*L106Ifs13**	0.35
STAD	chr10	114220823	Missense_Mutation	NA	V917A	0.22
UCEC	chr10	114210963	Silent	NA	F552F	0.36
UCEC	chr10	114227211	Missense_Mutation	NA	E1105D	0.34
UCEC	chr10	114231550	3'UTR	novel		0.35
UCEC	chr10	114231567	3'UTR	novel		0.29
UCEC	chr10	114227219	Missense_Mutation	novel	T1108I	0.26
UCEC	chr10	114231559	3'UTR	novel		0.17
UCEC	chr10	114187866	Missense_Mutation	NA	R12I	0.36
UCEC	chr10	114217624	Missense_Mutation	rs750552691	E764D	0.37
UCEC	chr10	114221389	Nonsense_Mutation	NA	E935*	0.45
UCEC	chr10	114213589	Splice_Site	novel	X692_splice	0.55
UCEC	chr10	114220604	Missense_Mutation	novel	A844V	0.35
UCEC	chr10	114221384	Missense_Mutation	rs755901940	T933M	0.26
UCEC	chr10	114231588	3'UTR	novel		0.2
UCEC	chr10	114217552	Missense_Mutation	NA	K740N	0.34
UCEC	chr10	114218500	Missense_Mutation	novel	E804K	0.51
UCEC	chr10	114228035	Splice_Region	rs745846290		0.38
UCEC	chr10	114218500	Missense_Mutation	novel	E804K	0.38
UCEC	chr10	114211975	Silent	novel	L590L	0.37
UCEC	chr10	114213352	Missense_Mutation	novel	K613M	0.37
UCEC	chr10	114220766	Missense_Mutation	NA	A898V	0.43
UCEC	chr10	114203418	Missense_Mutation	novel	D278Y	0.5
UCEC	chr10	114202261	Nonsense_Mutation	NA	S220*	0.44
UCEC	chr10	114220696	Missense_Mutation	rs770914554	D875N	0.32
UCEC	chr10	114212023	Silent	NA	K606K	0.25
UCEC	chr10	114220766	Missense_Mutation	NA	A898V	0.22
UCEC	chr10	114227244	Silent	NA	V1116V	0.1
UCEC	chr10	114210607	In_Frame_Ins	novel	I476_V477insYHQWLDKNQSVEATENNI	0.02
UCEC	chr10	114202276	Missense_Mutation	NA	K225T	0.48
UCEC	chr10	114203426	Silent	rs145466216	Y280Y	0.23
UCEC	chr10	114213482	Silent	NA	S656S	0.18
UCEC	chr10	114213553	Missense_Mutation	NA	V680A	0.2
UCEC	chr10	114190999	Missense_Mutation	novel	P122S	0.04
UCEC	chr10	114199192	Missense_Mutation	rs149031282	R135H	0.21
UCEC	chr10	114203076	Missense_Mutation	novel	D234G	0.18
UCEC	chr10	114204724	Splice_Region	novel	A376A	0.15
UCEC	chr10	114213388	Missense_Mutation	novel	C625Y	0.18
UCEC	chr10	114187846	Silent	rs138882204	S5S	0.37
UCEC	chr10	114228152	Intron	rs759591914		0.31
UCEC	chr10	114187868	Missense_Mutation	NA	N13H	0.39
UCEC	chr10	114211978	Silent	novel	C591C	0.19
UCEC	chr10	114210628	Missense_Mutation	NA	V478I	0.53
UCEC	chr10	114214034	Missense_Mutation	rs774487353	G711D	0.13
UCEC	chr10	114203162	Missense_Mutation	novel	T263A	0.38
UCEC	chr10	114231575	3'UTR	novel		0.41
UCEC	chr10	114199234	Missense_Mutation	NA	S149F	0.3
UCEC	chr10	114204887	Missense_Mutation	novel	N431H	0.38
UCEC	chr10	114214084	Nonsense_Mutation	novel	E728*	0.53
UCEC	chr10	114217552	Missense_Mutation	NA	K740N	0.38
UCEC	chr10	114227120	Missense_Mutation	novel	L1075S	0.43
UCEC	chr10	114188108	Missense_Mutation	novel	N93D	0.15
UCEC	chr10	114214024	Missense_Mutation	novel	V708I	0.4
UCEC	chr10	114218465	Missense_Mutation	rs377385869	H792R	0.26
UCEC	chr10	114221384	Missense_Mutation	rs755901940	T933M	0.33
UCEC	chr10	114204836	Missense_Mutation	novel	D414N	0.36
UCEC	chr10	114188044	Silent	novel	E71E	0.34
UCEC	chr10	114218432	Missense_Mutation	NA	R781H	0.33
UCEC	chr10	114228232	Intron	novel		0.42
UCEC	chr10	114203552	Missense_Mutation	novel	K322N	0.45
UCEC	chr10	114204836	Missense_Mutation	novel	D414N	0.45
UCEC	chr10	114206317	Silent	novel	E457E	0.47
UCEC	chr10	114214095	Silent	novel	C731C	0.48
UCEC	chr10	114213513	Missense_Mutation	novel	L667I	0.09
UCEC	chr10	114221394	Silent	novel	L936L	0.44
UCEC	chr10	114228195	Intron	novel		0.31
UCEC	chr10	114188008	Missense_Mutation	rs781068186	E59D	0.45
UCEC	chr10	114214088	Missense_Mutation	novel	F729C	0.26
UCEC	chr10	114218453	Missense_Mutation	novel	L788S	0.39
UCEC	chr10	114226181	Missense_Mutation	rs576653939	A1047V	0.22	TUDOR
UCEC	chr10	114206321	In_Frame_Ins	novel	A459delinsGQRRRT	0.09
UCEC	chr10	114213579	Nonsense_Mutation	NA	E689*	0.2
UCEC	chr10	114210910	Missense_Mutation	novel	P535S	0.18
UCEC	chr10	114210911	Frame_Shift_Ins	novel	*P536Ffs43**	0.15
UCEC	chr10	114206321	In_Frame_Ins	novel	A459delinsGQRRRT	0.1
UCEC	chr10	114204157	Missense_Mutation	novel	I356L	0.37
UCEC	chr10	114222681	Silent	rs767859168	D995D	0.12
UCEC	chr10	114188038	Silent	novel	L69L	0.52
UCEC	chr10	114210684	Missense_Mutation	novel	F496L	0.43
UCEC	chr10	114228087	Missense_Mutation	novel	N1167T	0.4
UCEC	chr10	114206321	Frame_Shift_Ins	novel	*A459Gfs13**	0.06
UCEC	chr10	114206322	Frame_Shift_Ins	novel	*D460Efs14**	0.06
UCEC	chr10	114211946	Missense_Mutation	novel	N581Y	0.05
UCEC	chr10	114217552	Missense_Mutation	NA	K740N	0.09
UCEC	chr10	114210628	Missense_Mutation	NA	V478I	0.46
UCEC	chr10	114202284	Missense_Mutation	novel	E228K	0.08
UCEC	chr10	114213482	Silent	rs368173748	S656S	0.28
UCEC	chr10	114226182	Silent	rs748715176	A1047A	0.44
UCEC	chr10	114228037	Splice_Site	novel	X1151_splice	0.4
UCEC	chr10	114199177	Missense_Mutation	NA	P130L	0.36
UCEC	chr10	114203392	Missense_Mutation	rs369155631	T269M	0.28
UCEC	chr10	114201492	Silent	NA	I204I	0.39
UCEC	chr10	114199205	Frame_Shift_Del	NA	*K141Nfs2**	0.26
UCEC	chr10	114227258	Frame_Shift_Ins	NA	*N1123Kfs17**	0.31
UCEC	chr10	114228042	Frame_Shift_Del	novel	*K1153Nfs10**	0.52
UCEC	chr10	114204173	Missense_Mutation	NA	R361I	0.23
UCEC	chr10	114204872	Nonsense_Mutation	NA	E426*	0.37
UCEC	chr10	114187845	Missense_Mutation	rs146228512	S5L	0.4
UCEC	chr10	114211884	Missense_Mutation	novel	R560H	0.2
UCEC	chr10	114222682	Missense_Mutation	rs199536592	A996T	0.19	TUDOR
UCEC	chr10	114231604	3'UTR	novel		0.18
UCEC	chr10	114226104	Missense_Mutation	novel	E1021D	0.14	TUDOR
UCEC	chr10	114187903	Silent	novel	E24E	0.08
UCEC	chr10	114206264	Missense_Mutation	NA	L440F	0.28
UCEC	chr10	114213487	Missense_Mutation	rs371770651	T658M	0.27
UCEC	chr10	114211884	Missense_Mutation	novel	R560H	0.38
UCEC	chr10	114204895	Splice_Site	novel	X433_splice	0.39
UCEC	chr10	114213395	Frame_Shift_Ins	novel	*L630Tfs25**	0.34
UCEC	chr10	114226067	Missense_Mutation	novel	R1009H	0.37	TUDOR
UCEC	chr10	114201410	Missense_Mutation	NA	G177E	0.43
UCEC	chr10	114210703	Missense_Mutation	novel	I503V	0.39
UCS	chr10	114221401	Missense_Mutation	novel	D939Y	0.45	TUDOR

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1	0.19593
CHOL	DEL	0.2778	0.048655
COAD	DEL	0.1596	9.4741e-07
LIHC	DEL	0.2514	5.7505e-06
MESO	DEL	0.2759	0.00015289
OV	DEL	0.3178	5.3759e-12
PAAD	DEL	0.1141	0.169
READ	DEL	0.2121	0.014135
THYM	DEL	0.0325	0.10563
UCS	DEL	0.2857	0.1218

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.019	Kaplan-Meier Survival Analysis
HNSC	0.012	Kaplan-Meier Survival Analysis
KIRP	0.016	Kaplan-Meier Survival Analysis
GBM	0.026	Kaplan-Meier Survival Analysis
LIHC	0.0085	Kaplan-Meier Survival Analysis
CHOL	0.018	Kaplan-Meier Survival Analysis
LUAD	0.0038	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742