EuRBPDB

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  • Description
  • RBDs
  • RBPome
  • Expression
  • Transcripts
  • Gene Model
  • PPI
  • Paralogs
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000096746 (Gene tree)
Gene ID
3189
Gene Symbol
HNRNPH3
Alias
2H9|HNRPH3
Full Name
heterogeneous nuclear ribonucleoprotein H3
Gene Type
protein_coding
Species
Homo_sapiens
Status
confidence
Strand
Plus strand
Length
12,023 bases
Position
chr10:68,331,174-68,343,196
Accession
5043
RBP type
canonical RBP
Summary
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is localized in nuclear bodies of the nucleus. This protein is involved in the splicing process and it also participates in early heat shock-induced splicing arrest by transiently leaving the hnRNP complexes. Several alternatively spliced transcript variants have been noted for this gene, however, not all are fully characterized. [provided by RefSeq, Jul 2008]
RNA binding domains(RBDs)
Protein IDDomain Pfam IDE-value Domain number Total number
ENSP00000346726RRM_1PF00076.223e-2112
ENSP00000346726RRM_1PF00076.223e-2122
ENSP00000265866RRM_1PF00076.223.5e-2112
ENSP00000265866RRM_1PF00076.223.5e-2122
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNANascentRICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & MCF10A2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & U2OS2019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
27453046Comprehensive Identification of RNA-Binding Domains in Human CellsRIC & Hela2016 Aug 18Castello ADOI: 10.1016/j.molcel.2016.06.029
30352994Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome captureRIC & Jurkat2018 Oct 23Perez-Perri JIDOI:10.1038/s41467-018-06557-8
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000486854HNRNPH3-209635--- (aa)--
ENST00000490442HNRNPH3-2101521--- (aa)--
ENST00000481819HNRNPH3-2082704--- (aa)--
ENST00000467249HNRNPH3-204566--- (aa)--
ENST00000461310HNRNPH3-203648--- (aa)--
ENST00000491200HNRNPH3-2112308--- (aa)--
ENST00000265866HNRNPH3-2012339-ENSP00000265866346 (aa)-P31942
ENST00000478698HNRNPH3-2061507--- (aa)--
ENST00000469172HNRNPH3-2053356--- (aa)--
ENST00000480987HNRNPH3-207752--- (aa)--
ENST00000354695HNRNPH3-2021332-ENSP00000346726331 (aa)-P31942
Gene Model
Click here to download ENSG00000096746's gene model file
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000096746's network

* RBP PPI network refers to all genes directly bind to RBP
Paralogs
Ensembl IDGene SymbolCoverageIdentiy ParalogGene SymbolCoverageIdentiy
ENSG00000096746HNRNPH37442.471ENSG00000132463GRSF15966.234
ENSG00000096746HNRNPH39159.940ENSG00000126945HNRNPH29357.522
ENSG00000096746HNRNPH39557.012ENSG00000169813HNRNPF9240.000
ENSG00000096746HNRNPH39959.673ENSG00000169045HNRNPH19581.579
Orthologs
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000096746HNRNPH38069.097ENSAPOG00000021843hnrnph39170.000Acanthochromis_polyacanthus
ENSG00000096746HNRNPH310099.422ENSAMEG00000018064HNRNPH310099.422Ailuropoda_melanoleuca
ENSG00000096746HNRNPH39166.207ENSACIG00000007244hnrnph39667.376Amphilophus_citrinellus
ENSG00000096746HNRNPH38068.056ENSAOCG00000011957hnrnph39170.000Amphiprion_ocellaris
ENSG00000096746HNRNPH38068.056ENSAPEG00000006201hnrnph39170.000Amphiprion_percula
ENSG00000096746HNRNPH38067.931ENSATEG00000021208hnrnph39069.504Anabas_testudineus
ENSG00000096746HNRNPH39385.321ENSAPLG00000001116HNRNPH39190.312Anas_platyrhynchos
ENSG00000096746HNRNPH310089.914ENSACAG00000010365HNRNPH39190.536Anolis_carolinensis
ENSG00000096746HNRNPH39171.069ENSANAG00000024326HNRNPH39072.152Aotus_nancymaae
ENSG00000096746HNRNPH39667.018ENSACLG00000008447hnrnph39263.958Astatotilapia_calliptera
ENSG00000096746HNRNPH38069.825ENSAMXG00000021323hnrnph39171.223Astyanax_mexicanus
ENSG00000096746HNRNPH3100100.000ENSBTAG00000014316HNRNPH3100100.000Bos_taurus
ENSG00000096746HNRNPH3100100.000ENSCJAG00000019154HNRNPH3100100.000Callithrix_jacchus
ENSG00000096746HNRNPH3100100.000ENSCAFG00000013619HNRNPH3100100.000Canis_familiaris
ENSG00000096746HNRNPH3100100.000ENSCAFG00020026261HNRNPH3100100.000Canis_lupus_dingo
ENSG00000096746HNRNPH3100100.000ENSCHIG00000026467-100100.000Capra_hircus
ENSG00000096746HNRNPH3100100.000ENSTSYG00000005319-100100.000Carlito_syrichta
ENSG00000096746HNRNPH310086.705ENSCAPG00000013030HNRNPH310086.705Cavia_aperea
ENSG00000096746HNRNPH3100100.000ENSCPOG00000006397HNRNPH3100100.000Cavia_porcellus
ENSG00000096746HNRNPH3100100.000ENSCCAG00000028531HNRNPH3100100.000Cebus_capucinus
ENSG00000096746HNRNPH3100100.000ENSCATG00000039188HNRNPH3100100.000Cercocebus_atys
ENSG00000096746HNRNPH310099.711ENSCLAG00000010680HNRNPH310099.711Chinchilla_lanigera
ENSG00000096746HNRNPH3100100.000ENSCSAG00000007572HNRNPH3100100.000Chlorocebus_sabaeus
ENSG00000096746HNRNPH39596.753ENSCHOG00000012954HNRNPH310096.753Choloepus_hoffmanni
ENSG00000096746HNRNPH39192.767ENSCPBG00000019569HNRNPH39192.767Chrysemys_picta_bellii
ENSG00000096746HNRNPH3100100.000ENSCANG00000031750HNRNPH3100100.000Colobus_angolensis_palliatus
ENSG00000096746HNRNPH310098.266ENSCGRG00001024086Hnrnph310098.266Cricetulus_griseus_chok1gshd
ENSG00000096746HNRNPH310098.266ENSCGRG00000017341Hnrnph310098.266Cricetulus_griseus_crigri
ENSG00000096746HNRNPH39567.208ENSCSEG00000014207hnrnph39169.858Cynoglossus_semilaevis
ENSG00000096746HNRNPH38066.783ENSCVAG00000010461HNRNPH39066.308Cyprinodon_variegatus
ENSG00000096746HNRNPH38067.606ENSDARG00000039466hnrnph39568.293Danio_rerio
ENSG00000096746HNRNPH3100100.000ENSDNOG00000004881HNRNPH3100100.000Dasypus_novemcinctus
ENSG00000096746HNRNPH310098.844ENSDORG00000011470Hnrnph310098.844Dipodomys_ordii
ENSG00000096746HNRNPH3100100.000ENSEASG00005015382HNRNPH3100100.000Equus_asinus_asinus
ENSG00000096746HNRNPH3100100.000ENSECAG00000007190HNRNPH3100100.000Equus_caballus
ENSG00000096746HNRNPH38898.507ENSEEUG00000005025HNRNPH38298.507Erinaceus_europaeus
ENSG00000096746HNRNPH39568.440ENSELUG00000018424hnrnph39170.909Esox_lucius
ENSG00000096746HNRNPH3100100.000ENSFCAG00000032291HNRNPH3100100.000Felis_catus
ENSG00000096746HNRNPH39387.730ENSFALG00000012964HNRNPH39187.188Ficedula_albicollis
ENSG00000096746HNRNPH39171.000ENSFDAG00000014531-9070.000Fukomys_damarensis
ENSG00000096746HNRNPH3100100.000ENSFDAG00000008155-100100.000Fukomys_damarensis
ENSG00000096746HNRNPH39466.783ENSFHEG00000010727HNRNPH39066.308Fundulus_heteroclitus
ENSG00000096746HNRNPH38069.718ENSGMOG00000012413hnrnph39666.787Gadus_morhua
ENSG00000096746HNRNPH39387.730ENSGALG00000003947HNRNPH39187.188Gallus_gallus
ENSG00000096746HNRNPH38066.084ENSGAFG00000005286HNRNPH39265.299Gambusia_affinis
ENSG00000096746HNRNPH39967.247ENSGACG00000016118hnrnph38967.972Gasterosteus_aculeatus
ENSG00000096746HNRNPH39192.079ENSGAGG00000003144HNRNPH39192.079Gopherus_agassizii
ENSG00000096746HNRNPH3100100.000ENSGGOG00000025378HNRNPH3100100.000Gorilla_gorilla
ENSG00000096746HNRNPH39669.024ENSHBUG00000018007hnrnph39164.982Haplochromis_burtoni
ENSG00000096746HNRNPH38689.123ENSHGLG00000008716-9585.809Heterocephalus_glaber_female
ENSG00000096746HNRNPH3100100.000ENSHGLG00000011321-100100.000Heterocephalus_glaber_female
ENSG00000096746HNRNPH38689.123ENSHGLG00100000514-9585.809Heterocephalus_glaber_male
ENSG00000096746HNRNPH3100100.000ENSHGLG00100017813-100100.000Heterocephalus_glaber_male
ENSG00000096746HNRNPH39466.431ENSHCOG00000014335hnrnph39164.875Hippocampus_comes
ENSG00000096746HNRNPH37969.825ENSIPUG00000016015hnrnph39071.326Ictalurus_punctatus
ENSG00000096746HNRNPH3100100.000ENSSTOG00000011676HNRNPH3100100.000Ictidomys_tridecemlineatus
ENSG00000096746HNRNPH310099.094ENSJJAG00000022736-10099.094Jaculus_jaculus
ENSG00000096746HNRNPH39968.990ENSKMAG00000020517hnrnph39168.817Kryptolebias_marmoratus
ENSG00000096746HNRNPH36062.222ENSLBEG00000001661hnrnph37962.222Labrus_bergylta
ENSG00000096746HNRNPH39765.744ENSLBEG00000008709hnrnph38869.149Labrus_bergylta
ENSG00000096746HNRNPH39168.153ENSLACG00000013291HNRNPH37867.732Latimeria_chalumnae
ENSG00000096746HNRNPH39370.606ENSLOCG00000009247hnrnph39571.166Lepisosteus_oculatus
ENSG00000096746HNRNPH310099.135ENSLAFG00000012955HNRNPH310099.135Loxodonta_africana
ENSG00000096746HNRNPH3100100.000ENSMFAG00000039598HNRNPH3100100.000Macaca_fascicularis
ENSG00000096746HNRNPH3100100.000ENSMMUG00000009792HNRNPH3100100.000Macaca_mulatta
ENSG00000096746HNRNPH3100100.000ENSMNEG00000038866HNRNPH3100100.000Macaca_nemestrina
ENSG00000096746HNRNPH310099.711ENSMLEG00000038699HNRNPH310099.711Mandrillus_leucophaeus
ENSG00000096746HNRNPH39668.966ENSMAMG00000020155hnrnph39068.794Mastacembelus_armatus
ENSG00000096746HNRNPH39669.024ENSMZEG00005011374hnrnph39167.376Maylandia_zebra
ENSG00000096746HNRNPH39381.902ENSMGAG00000003795HNRNPH39181.818Meleagris_gallopavo
ENSG00000096746HNRNPH310099.711ENSMAUG00000022233Hnrnph310099.711Mesocricetus_auratus
ENSG00000096746HNRNPH3100100.000ENSMICG00000007581HNRNPH3100100.000Microcebus_murinus
ENSG00000096746HNRNPH310098.266ENSMOCG00000008138Hnrnph310098.266Microtus_ochrogaster
ENSG00000096746HNRNPH39867.483ENSMMOG00000015374hnrnph37969.176Mola_mola
ENSG00000096746HNRNPH310097.892ENSMODG00000017283HNRNPH310097.892Monodelphis_domestica
ENSG00000096746HNRNPH38565.862ENSMALG00000005779hnrnph38866.667Monopterus_albus
ENSG00000096746HNRNPH310099.422MGP_CAROLIEiJ_G0015396Hnrnph310099.422Mus_caroli
ENSG00000096746HNRNPH310099.422ENSMUSG00000020069Hnrnph310099.422Mus_musculus
ENSG00000096746HNRNPH310098.844MGP_PahariEiJ_G0030812Hnrnph310098.844Mus_pahari
ENSG00000096746HNRNPH310099.422MGP_SPRETEiJ_G0016207Hnrnph310099.422Mus_spretus
ENSG00000096746HNRNPH39399.690ENSMPUG00000011997HNRNPH39199.690Mustela_putorius_furo
ENSG00000096746HNRNPH3100100.000ENSMLUG00000000143HNRNPH3100100.000Myotis_lucifugus
ENSG00000096746HNRNPH310099.422ENSNGAG00000011731Hnrnph310099.422Nannospalax_galili
ENSG00000096746HNRNPH39670.000ENSNBRG00000004383hnrnph39168.085Neolamprologus_brichardi
ENSG00000096746HNRNPH3100100.000ENSNLEG00000011843HNRNPH3100100.000Nomascus_leucogenys
ENSG00000096746HNRNPH310096.254ENSMEUG00000013139HNRNPH310096.254Notamacropus_eugenii
ENSG00000096746HNRNPH310099.422ENSOPRG00000014850HNRNPH39999.422Ochotona_princeps
ENSG00000096746HNRNPH310099.133ENSODEG00000004517HNRNPH310099.133Octodon_degus
ENSG00000096746HNRNPH39668.621ENSONIG00000017042hnrnph39167.730Oreochromis_niloticus
ENSG00000096746HNRNPH310097.289ENSOANG00000002260HNRNPH310097.289Ornithorhynchus_anatinus
ENSG00000096746HNRNPH3100100.000ENSOCUG00000004443HNRNPH3100100.000Oryctolagus_cuniculus
ENSG00000096746HNRNPH39568.182ENSORLG00000010499hnrnph39164.413Oryzias_latipes
ENSG00000096746HNRNPH39668.881ENSORLG00020003778hnrnph39167.730Oryzias_latipes_hni
ENSG00000096746HNRNPH39568.531ENSORLG00015001985hnrnph39167.376Oryzias_latipes_hsok
ENSG00000096746HNRNPH39669.231ENSOMEG00000005017hnrnph39167.021Oryzias_melastigma
ENSG00000096746HNRNPH310099.711ENSOGAG00000012493HNRNPH310099.711Otolemur_garnettii
ENSG00000096746HNRNPH310099.711ENSOARG00000004981HNRNPH310099.711Ovis_aries
ENSG00000096746HNRNPH3100100.000ENSPPAG00000033764HNRNPH3100100.000Pan_paniscus
ENSG00000096746HNRNPH3100100.000ENSPPRG00000004134HNRNPH3100100.000Panthera_pardus
ENSG00000096746HNRNPH3100100.000ENSPTIG00000011896HNRNPH3100100.000Panthera_tigris_altaica
ENSG00000096746HNRNPH3100100.000ENSPTRG00000002553HNRNPH3100100.000Pan_troglodytes
ENSG00000096746HNRNPH3100100.000ENSPANG00000022105HNRNPH3100100.000Papio_anubis
ENSG00000096746HNRNPH37868.914ENSPKIG00000008373HNRNPH38869.549Paramormyrops_kingsleyae
ENSG00000096746HNRNPH39192.409ENSPSIG00000007332HNRNPH39192.409Pelodiscus_sinensis
ENSG00000096746HNRNPH37868.727ENSPMGG00000001373hnrnph39667.636Periophthalmus_magnuspinnatus
ENSG00000096746HNRNPH3100100.000ENSPEMG00000017748Hnrnph3100100.000Peromyscus_maniculatus_bairdii
ENSG00000096746HNRNPH310096.988ENSPCIG00000014462HNRNPH310096.988Phascolarctos_cinereus
ENSG00000096746HNRNPH38966.434ENSPFOG00000015322HNRNPH39067.384Poecilia_formosa
ENSG00000096746HNRNPH39466.434ENSPLAG00000008895-9067.384Poecilia_latipinna
ENSG00000096746HNRNPH38965.854ENSPMEG00000008778-8966.308Poecilia_mexicana
ENSG00000096746HNRNPH39466.784ENSPREG00000009812HNRNPH39067.384Poecilia_reticulata
ENSG00000096746HNRNPH310099.711ENSPPYG00000002397HNRNPH310099.711Pongo_abelii
ENSG00000096746HNRNPH310091.092ENSPCAG00000000111HNRNPH310091.092Procavia_capensis
ENSG00000096746HNRNPH3100100.000ENSPCOG00000028162HNRNPH3100100.000Propithecus_coquereli
ENSG00000096746HNRNPH386100.000ENSPVAG00000008037HNRNPH386100.000Pteropus_vampyrus
ENSG00000096746HNRNPH39669.360ENSPNYG00000016363hnrnph39167.730Pundamilia_nyererei
ENSG00000096746HNRNPH38069.580ENSPNAG00000000466hnrnph39170.863Pygocentrus_nattereri
ENSG00000096746HNRNPH310099.422ENSRNOG00000048193Hnrnph310099.422Rattus_norvegicus
ENSG00000096746HNRNPH3100100.000ENSRBIG00000028004HNRNPH3100100.000Rhinopithecus_bieti
ENSG00000096746HNRNPH3100100.000ENSRROG00000031653HNRNPH3100100.000Rhinopithecus_roxellana
ENSG00000096746HNRNPH3100100.000ENSSBOG00000022722HNRNPH3100100.000Saimiri_boliviensis_boliviensis
ENSG00000096746HNRNPH310095.965ENSSHAG00000010909HNRNPH310095.965Sarcophilus_harrisii
ENSG00000096746HNRNPH39969.675ENSSFOG00015015000hnrnph39071.119Scleropages_formosus
ENSG00000096746HNRNPH38366.319ENSSMAG00000004504hnrnph39067.972Scophthalmus_maximus
ENSG00000096746HNRNPH38069.896ENSSDUG00000000160hnrnph38470.567Seriola_dumerili
ENSG00000096746HNRNPH38069.896ENSSLDG00000025679hnrnph39070.567Seriola_lalandi_dorsalis
ENSG00000096746HNRNPH310085.549ENSSARG00000013863HNRNPH310085.549Sorex_araneus
ENSG00000096746HNRNPH39190.566ENSSPUG00000001687-9190.566Sphenodon_punctatus
ENSG00000096746HNRNPH36876.871ENSSPUG00000009577-8170.866Sphenodon_punctatus
ENSG00000096746HNRNPH38068.056ENSSPAG00000013124hnrnph38670.357Stegastes_partitus
ENSG00000096746HNRNPH3100100.000ENSSSCG00000010238HNRNPH3100100.000Sus_scrofa
ENSG00000096746HNRNPH39387.730ENSTGUG00000003609HNRNPH39187.188Taeniopygia_guttata
ENSG00000096746HNRNPH39665.449ENSTRUG00000023443hnrnph36780.000Takifugu_rubripes
ENSG00000096746HNRNPH37870.609ENSTNIG00000013788hnrnph39869.534Tetraodon_nigroviridis
ENSG00000096746HNRNPH310094.220ENSTBEG00000006114HNRNPH310094.220Tupaia_belangeri
ENSG00000096746HNRNPH310099.711ENSTTRG00000013322HNRNPH310099.711Tursiops_truncatus
ENSG00000096746HNRNPH39399.381ENSUAMG00000011846HNRNPH39899.381Ursus_americanus
ENSG00000096746HNRNPH310099.698ENSUMAG00000007264HNRNPH310099.698Ursus_maritimus
ENSG00000096746HNRNPH3100100.000ENSVPAG00000011814HNRNPH3100100.000Vicugna_pacos
ENSG00000096746HNRNPH3100100.000ENSVVUG00000020145HNRNPH3100100.000Vulpes_vulpes
ENSG00000096746HNRNPH39678.221ENSXETG00000023567hnrnph39577.570Xenopus_tropicalis
ENSG00000096746HNRNPH39465.672ENSXCOG00000012095hnrnph39165.299Xiphophorus_couchianus
ENSG00000096746HNRNPH38066.434ENSXMAG00000014775HNRNPH39067.384Xiphophorus_maculatus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000398mRNA splicing, via spliceosome10858537.NASProcess
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0003723RNA binding10858537.NASFunction
GO:0005515protein binding22365833.22446626.22720776.26496610.IPIFunction
GO:0005634nucleus22720776.IDAComponent
GO:0005654nucleoplasm-IDAComponent
GO:0005681spliceosomal complex10858537.NASComponent
GO:0005681spliceosomal complex8999868.TASComponent
GO:0006396RNA processing8999868.TASProcess
GO:0008380RNA splicing8999868.TASProcess
GO:0030855epithelial cell differentiation21492153.IEPProcess

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