EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000099817 (Gene tree)
Gene ID: 5434
Gene Symbol: POLR2E
Alias: RPB5|RPABC1|XAP4|hRPB25|hsRPB5
Full Name: RNA polymerase II subunit E
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 8,814 bases
Position: chr19:1,086,579-1,095,392
Accession: 9192
RBP type: canonical RBP
Summary: This gene encodes the fifth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. This subunit is shared by the other two DNA-directed RNA polymerases and is present in two-fold molar excess over the other polymerase subunits. An interaction between this subunit and a hepatitis virus transactivating protein has been demonstrated, suggesting that interaction between transcriptional activators and the polymerase can occur through this subunit. A pseudogene is located on chromosome 11. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000479813	RNA_pol_Rpb5_N	PF03871.14	2.4e-33	1	1
ENSP00000464739	RNA_pol_Rpb5_N	PF03871.14	3e-33	1	1
ENSP00000478303	RNA_pol_Rpb5_N	PF03871.14	3e-33	1	1
ENSP00000485021	RNA_pol_Rpb5_N	PF03871.14	3e-33	1	1
ENSP00000480562	RNA_pol_Rpb5_C	PF01191.19	1.4e-34	1	1
ENSP00000464739	RNA_pol_Rpb5_C	PF01191.19	2.2e-34	1	1
ENSP00000478303	RNA_pol_Rpb5_C	PF01191.19	2.2e-34	1	1
ENSP00000485021	RNA_pol_Rpb5_C	PF01191.19	2.2e-34	1	1
ENSP00000479813	RNA_pol_Rpb5_C	PF01191.19	2.3e-30	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
30484156	The Yeast Prefoldin Bud27.	Adv Exp Med Biol	2018	Martinez-Fernandez V	doi: 10.1007/978-3-030-00737-9_8.
17179178	Functional organization of the Rpb5 subunit shared by the three yeast RNA polymerases.	Nucleic Acids Res	2007	Zaros C	-
23459708	The prefoldin bud27 mediates the assembly of the eukaryotic RNA polymerases in an rpb5-dependent manner.	PLoS Genet	2013	Miron-Garcia MC	doi: 10.1371/journal.pgen.1003297
30484154	Role of the Unconventional Prefoldin Proteins URI and UXT in Transcription Regulation.	Adv Exp Med Biol	2018	Thomas PA	doi: 10.1007/978-3-030-00737-9_6.
9819440	RMP, a novel RNA polymerase II subunit 5-interacting protein, counteracts transactivation by hepatitis B virus X protein.	Mol Cell Biol	1998 Dec	Dorjsuren D	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000591767	POLR2E-209	1214	-	ENSP00000465066	68 (aa)	-	K7EJ87
ENST00000589737	POLR2E-206	1105	-	ENSP00000467905	51 (aa)	-	K7EQN2
ENST00000615234	POLR2E-213	2831	-	ENSP00000478303	210 (aa)	-	P19388
ENST00000592597	POLR2E-210	440	-	-	- (aa)	-	-
ENST00000590060	POLR2E-207	1052	-	ENSP00000479560	83 (aa)	-	A0A087WVN5
ENST00000215587	POLR2E-201	1286	-	ENSP00000215587	204 (aa)	-	A0A0A0MQR7
ENST00000614705	POLR2E-212	589	-	-	- (aa)	-	-
ENST00000586746	POLR2E-204	1096	-	ENSP00000464739	210 (aa)	-	P19388
ENST00000586215	POLR2E-203	756	-	-	- (aa)	-	-
ENST00000585838	POLR2E-202	487	XM_017026883	ENSP00000480562	134 (aa)	XP_016882372	A0A087WWX0
ENST00000586817	POLR2E-205	2441	-	-	- (aa)	-	-
ENST00000591709	POLR2E-208	685	-	-	- (aa)	-	-
ENST00000619917	POLR2E-214	932	-	ENSP00000479813	184 (aa)	-	A0A087WVZ9
ENST00000612655	POLR2E-211	1749	XM_011528070	ENSP00000485021	210 (aa)	XP_011526372	P19388

Gene Model

Click here to download ENSG00000099817's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03020	RNA polymerase	KEGG
hsa04623	Cytosolic DNA-sensing pathway	KEGG
hsa05016	Huntington disease	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000099817	Blood Pressure	2.2317604E-005	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000099817	rs3787016	19	1090804	?	Cortical amyloid beta load	29860282	[NR] unit increase	0.13	EFO_0007707

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000099817's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000099817	POLR2E	100	95.238	ENSAPOG00000002935	polr2eb	100	95.238	Acanthochromis_polyacanthus
ENSG00000099817	POLR2E	100	99.524	ENSAMEG00000003159	POLR2E	100	99.524	Ailuropoda_melanoleuca
ENSG00000099817	POLR2E	99	94.536	ENSACIG00000024371	polr2eb	100	94.536	Amphilophus_citrinellus
ENSG00000099817	POLR2E	100	95.238	ENSAOCG00000018166	polr2eb	100	95.238	Amphiprion_ocellaris
ENSG00000099817	POLR2E	100	95.238	ENSAPEG00000009000	polr2eb	100	95.238	Amphiprion_percula
ENSG00000099817	POLR2E	100	95.238	ENSATEG00000023760	polr2eb	100	95.238	Anabas_testudineus
ENSG00000099817	POLR2E	100	99.524	ENSANAG00000038488	POLR2E	100	99.524	Aotus_nancymaae
ENSG00000099817	POLR2E	100	95.714	ENSACLG00000005254	polr2eb	100	95.714	Astatotilapia_calliptera
ENSG00000099817	POLR2E	100	95.714	ENSAMXG00000018915	POLR2E	100	95.714	Astyanax_mexicanus
ENSG00000099817	POLR2E	100	99.524	ENSBTAG00000020776	POLR2E	100	99.524	Bos_taurus
ENSG00000099817	POLR2E	99	78.788	WBGene00019246	rpb-5	99	77.885	Caenorhabditis_elegans
ENSG00000099817	POLR2E	99	100.000	ENSCJAG00000007666	-	73	100.000	Callithrix_jacchus
ENSG00000099817	POLR2E	100	96.190	ENSCAFG00000019546	POLR2E	100	96.190	Canis_familiaris
ENSG00000099817	POLR2E	100	99.524	ENSCAFG00020017111	POLR2E	100	99.524	Canis_lupus_dingo
ENSG00000099817	POLR2E	100	99.524	ENSCHIG00000014151	POLR2E	100	99.524	Capra_hircus
ENSG00000099817	POLR2E	100	80.930	ENSTSYG00000026377	POLR2E	100	80.930	Carlito_syrichta
ENSG00000099817	POLR2E	99	100.000	ENSCAPG00000010843	POLR2E	93	99.479	Cavia_aperea
ENSG00000099817	POLR2E	100	99.524	ENSCPOG00000001542	POLR2E	100	99.524	Cavia_porcellus
ENSG00000099817	POLR2E	100	99.524	ENSCCAG00000025658	POLR2E	100	99.524	Cebus_capucinus
ENSG00000099817	POLR2E	100	99.524	ENSCATG00000008926	POLR2E	100	99.524	Cercocebus_atys
ENSG00000099817	POLR2E	100	99.048	ENSCLAG00000014874	-	100	99.048	Chinchilla_lanigera
ENSG00000099817	POLR2E	96	86.822	ENSCLAG00000009238	-	100	76.098	Chinchilla_lanigera
ENSG00000099817	POLR2E	100	99.524	ENSCSAG00000012336	POLR2E	100	99.524	Chlorocebus_sabaeus
ENSG00000099817	POLR2E	100	99.048	ENSCPBG00000009702	POLR2E	100	99.048	Chrysemys_picta_bellii
ENSG00000099817	POLR2E	100	85.714	ENSCING00000024933	-	99	85.714	Ciona_intestinalis
ENSG00000099817	POLR2E	60	85.000	ENSCSAVG00000007138	-	100	85.000	Ciona_savignyi
ENSG00000099817	POLR2E	100	99.524	ENSCANG00000025560	POLR2E	100	99.524	Colobus_angolensis_palliatus
ENSG00000099817	POLR2E	100	98.571	ENSCGRG00001022927	Polr2e	100	98.571	Cricetulus_griseus_chok1gshd
ENSG00000099817	POLR2E	100	92.093	ENSCGRG00000016441	Polr2e	100	92.093	Cricetulus_griseus_crigri
ENSG00000099817	POLR2E	100	94.286	ENSCSEG00000007107	polr2eb	100	92.896	Cynoglossus_semilaevis
ENSG00000099817	POLR2E	100	95.238	ENSCVAG00000019940	polr2eb	100	95.238	Cyprinodon_variegatus
ENSG00000099817	POLR2E	100	94.286	ENSDARG00000026183	polr2eb	100	94.286	Danio_rerio
ENSG00000099817	POLR2E	93	99.471	ENSDNOG00000044994	POLR2E	84	99.474	Dasypus_novemcinctus
ENSG00000099817	POLR2E	100	99.524	ENSDORG00000001154	Polr2e	100	99.524	Dipodomys_ordii
ENSG00000099817	POLR2E	99	85.606	FBgn0033571	Rpb5	99	85.167	Drosophila_melanogaster
ENSG00000099817	POLR2E	80	95.455	ENSEBUG00000010159	-	97	74.874	Eptatretus_burgeri
ENSG00000099817	POLR2E	99	100.000	ENSEASG00005021615	POLR2E	58	100.000	Equus_asinus_asinus
ENSG00000099817	POLR2E	100	98.039	ENSECAG00000011124	POLR2E	100	98.907	Equus_caballus
ENSG00000099817	POLR2E	100	93.810	ENSELUG00000005815	POLR2E	100	93.810	Esox_lucius
ENSG00000099817	POLR2E	100	92.857	ENSELUG00000020646	polr2e	100	92.857	Esox_lucius
ENSG00000099817	POLR2E	100	99.048	ENSFCAG00000007318	POLR2E	100	99.451	Felis_catus
ENSG00000099817	POLR2E	99	99.248	ENSFALG00000013986	POLR2E	99	98.958	Ficedula_albicollis
ENSG00000099817	POLR2E	100	99.524	ENSFDAG00000014539	POLR2E	100	99.524	Fukomys_damarensis
ENSG00000099817	POLR2E	100	95.238	ENSFHEG00000022398	polr2eb	100	95.238	Fundulus_heteroclitus
ENSG00000099817	POLR2E	100	93.810	ENSGMOG00000007615	polr2eb	100	93.810	Gadus_morhua
ENSG00000099817	POLR2E	100	99.048	ENSGALG00000002591	POLR2E	100	99.048	Gallus_gallus
ENSG00000099817	POLR2E	100	95.714	ENSGAFG00000005087	polr2eb	100	95.714	Gambusia_affinis
ENSG00000099817	POLR2E	100	93.810	ENSGACG00000013247	polr2eb	100	93.810	Gasterosteus_aculeatus
ENSG00000099817	POLR2E	100	99.048	ENSGAGG00000008356	POLR2E	100	99.048	Gopherus_agassizii
ENSG00000099817	POLR2E	100	99.524	ENSGGOG00000011267	POLR2E	100	99.524	Gorilla_gorilla
ENSG00000099817	POLR2E	99	93.985	ENSHBUG00000011099	polr2eb	100	90.141	Haplochromis_burtoni
ENSG00000099817	POLR2E	99	100.000	ENSHGLG00000013330	POLR2E	100	98.571	Heterocephalus_glaber_female
ENSG00000099817	POLR2E	99	100.000	ENSHGLG00100011014	POLR2E	100	98.571	Heterocephalus_glaber_male
ENSG00000099817	POLR2E	100	93.810	ENSHCOG00000000906	polr2eb	100	93.810	Hippocampus_comes
ENSG00000099817	POLR2E	80	93.939	ENSHCOG00000012099	-	88	91.071	Hippocampus_comes
ENSG00000099817	POLR2E	100	95.238	ENSIPUG00000019801	polr2e	100	95.238	Ictalurus_punctatus
ENSG00000099817	POLR2E	100	99.524	ENSSTOG00000002853	POLR2E	100	99.524	Ictidomys_tridecemlineatus
ENSG00000099817	POLR2E	100	98.571	ENSJJAG00000016595	-	100	98.571	Jaculus_jaculus
ENSG00000099817	POLR2E	99	90.710	ENSJJAG00000003145	-	100	90.710	Jaculus_jaculus
ENSG00000099817	POLR2E	79	80.745	ENSJJAG00000015812	-	100	80.745	Jaculus_jaculus
ENSG00000099817	POLR2E	100	95.238	ENSKMAG00000005954	polr2eb	100	95.238	Kryptolebias_marmoratus
ENSG00000099817	POLR2E	100	95.238	ENSLBEG00000024802	polr2eb	100	95.238	Labrus_bergylta
ENSG00000099817	POLR2E	100	95.238	ENSLACG00000013686	POLR2E	100	95.238	Latimeria_chalumnae
ENSG00000099817	POLR2E	80	95.455	ENSLOCG00000004599	POLR2E	100	96.296	Lepisosteus_oculatus
ENSG00000099817	POLR2E	99	99.248	ENSLAFG00000025587	POLR2E	100	80.189	Loxodonta_africana
ENSG00000099817	POLR2E	100	99.524	ENSMFAG00000002884	POLR2E	100	99.524	Macaca_fascicularis
ENSG00000099817	POLR2E	100	99.524	ENSMMUG00000013927	POLR2E	100	99.524	Macaca_mulatta
ENSG00000099817	POLR2E	100	66.351	ENSMNEG00000033452	-	100	66.351	Macaca_nemestrina
ENSG00000099817	POLR2E	100	99.524	ENSMNEG00000034046	-	100	99.524	Macaca_nemestrina
ENSG00000099817	POLR2E	92	80.829	ENSMLEG00000012405	POLR2E	94	80.829	Mandrillus_leucophaeus
ENSG00000099817	POLR2E	100	95.238	ENSMAMG00000018703	polr2eb	100	95.238	Mastacembelus_armatus
ENSG00000099817	POLR2E	99	94.536	ENSMZEG00005010796	polr2eb	100	94.536	Maylandia_zebra
ENSG00000099817	POLR2E	99	99.248	ENSMGAG00000003769	POLR2E	100	97.630	Meleagris_gallopavo
ENSG00000099817	POLR2E	99	98.496	ENSMAUG00000010125	-	100	98.429	Mesocricetus_auratus
ENSG00000099817	POLR2E	86	86.957	ENSMAUG00000011003	-	100	67.143	Mesocricetus_auratus
ENSG00000099817	POLR2E	100	99.524	ENSMICG00000013063	POLR2E	100	99.524	Microcebus_murinus
ENSG00000099817	POLR2E	100	98.571	ENSMOCG00000013414	Polr2e	100	98.571	Microtus_ochrogaster
ENSG00000099817	POLR2E	99	84.211	ENSMMOG00000001167	polr2eb	88	85.864	Mola_mola
ENSG00000099817	POLR2E	99	92.350	ENSMMOG00000001161	polr2eb	100	92.350	Mola_mola
ENSG00000099817	POLR2E	100	99.048	ENSMODG00000005494	POLR2E	100	99.048	Monodelphis_domestica
ENSG00000099817	POLR2E	100	95.714	ENSMALG00000021888	polr2eb	100	95.714	Monopterus_albus
ENSG00000099817	POLR2E	100	98.571	MGP_CAROLIEiJ_G0015561	Polr2e	100	98.571	Mus_caroli
ENSG00000099817	POLR2E	100	98.571	ENSMUSG00000004667	Polr2e	100	98.571	Mus_musculus
ENSG00000099817	POLR2E	100	98.571	MGP_PahariEiJ_G0030974	Polr2e	100	98.571	Mus_pahari
ENSG00000099817	POLR2E	100	98.571	MGP_SPRETEiJ_G0016379	Polr2e	100	98.571	Mus_spretus
ENSG00000099817	POLR2E	100	98.571	ENSMPUG00000008953	POLR2E	100	98.571	Mustela_putorius_furo
ENSG00000099817	POLR2E	100	99.524	ENSMLUG00000013193	POLR2E	100	99.524	Myotis_lucifugus
ENSG00000099817	POLR2E	73	96.721	ENSMLUG00000006376	-	100	82.716	Myotis_lucifugus
ENSG00000099817	POLR2E	100	98.571	ENSNGAG00000001147	Polr2e	100	98.571	Nannospalax_galili
ENSG00000099817	POLR2E	88	73.743	ENSNGAG00000017344	-	96	73.743	Nannospalax_galili
ENSG00000099817	POLR2E	99	94.536	ENSNBRG00000022772	polr2eb	100	94.536	Neolamprologus_brichardi
ENSG00000099817	POLR2E	100	95.735	ENSNLEG00000001207	-	100	95.735	Nomascus_leucogenys
ENSG00000099817	POLR2E	100	76.667	ENSNLEG00000031364	-	100	76.667	Nomascus_leucogenys
ENSG00000099817	POLR2E	100	86.667	ENSOPRG00000008331	POLR2E	100	86.667	Ochotona_princeps
ENSG00000099817	POLR2E	99	73.822	ENSODEG00000011490	-	99	73.822	Octodon_degus
ENSG00000099817	POLR2E	100	99.524	ENSODEG00000013230	-	100	99.524	Octodon_degus
ENSG00000099817	POLR2E	91	88.710	ENSODEG00000007985	-	100	88.710	Octodon_degus
ENSG00000099817	POLR2E	100	95.238	ENSONIG00000002519	polr2eb	100	95.238	Oreochromis_niloticus
ENSG00000099817	POLR2E	100	95.714	ENSORLG00000015346	polr2eb	100	95.714	Oryzias_latipes
ENSG00000099817	POLR2E	100	95.714	ENSORLG00020020700	polr2e	100	95.714	Oryzias_latipes_hni
ENSG00000099817	POLR2E	100	95.714	ENSORLG00015016842	polr2e	100	95.714	Oryzias_latipes_hsok
ENSG00000099817	POLR2E	100	95.238	ENSOMEG00000002709	polr2eb	100	95.238	Oryzias_melastigma
ENSG00000099817	POLR2E	100	99.524	ENSOGAG00000012311	POLR2E	100	99.524	Otolemur_garnettii
ENSG00000099817	POLR2E	100	99.524	ENSOARG00000010994	POLR2E	100	99.524	Ovis_aries
ENSG00000099817	POLR2E	99	100.000	ENSPPAG00000003145	POLR2E	100	99.476	Pan_paniscus
ENSG00000099817	POLR2E	100	99.048	ENSPPRG00000000777	POLR2E	100	99.451	Panthera_pardus
ENSG00000099817	POLR2E	90	89.697	ENSPTIG00000012237	POLR2E	98	93.421	Panthera_tigris_altaica
ENSG00000099817	POLR2E	100	99.524	ENSPTRG00000010183	POLR2E	100	99.524	Pan_troglodytes
ENSG00000099817	POLR2E	100	99.524	ENSPANG00000018011	POLR2E	100	99.524	Papio_anubis
ENSG00000099817	POLR2E	100	94.286	ENSPKIG00000024123	POLR2E	100	94.286	Paramormyrops_kingsleyae
ENSG00000099817	POLR2E	100	94.286	ENSPKIG00000009607	POLR2E	100	94.286	Paramormyrops_kingsleyae
ENSG00000099817	POLR2E	99	99.248	ENSPSIG00000002870	POLR2E	99	95.122	Pelodiscus_sinensis
ENSG00000099817	POLR2E	99	93.989	ENSPMGG00000014354	polr2eb	100	93.989	Periophthalmus_magnuspinnatus
ENSG00000099817	POLR2E	100	98.571	ENSPEMG00000023261	Polr2e	100	98.571	Peromyscus_maniculatus_bairdii
ENSG00000099817	POLR2E	100	91.509	ENSPCIG00000007312	POLR2E	84	91.509	Phascolarctos_cinereus
ENSG00000099817	POLR2E	100	95.714	ENSPFOG00000005734	polr2eb	100	95.714	Poecilia_formosa
ENSG00000099817	POLR2E	100	95.714	ENSPLAG00000014496	polr2eb	100	95.714	Poecilia_latipinna
ENSG00000099817	POLR2E	100	95.714	ENSPMEG00000008053	polr2eb	100	95.714	Poecilia_mexicana
ENSG00000099817	POLR2E	100	95.714	ENSPREG00000006489	polr2eb	100	95.714	Poecilia_reticulata
ENSG00000099817	POLR2E	100	91.943	ENSPPYG00000009305	POLR2E	100	91.943	Pongo_abelii
ENSG00000099817	POLR2E	83	100.000	ENSPCAG00000016605	POLR2E	100	100.000	Procavia_capensis
ENSG00000099817	POLR2E	100	99.524	ENSPCOG00000014491	POLR2E	100	99.524	Propithecus_coquereli
ENSG00000099817	POLR2E	65	100.000	ENSPVAG00000007718	-	55	99.138	Pteropus_vampyrus
ENSG00000099817	POLR2E	93	95.238	ENSPNYG00000019797	polr2eb	96	95.263	Pundamilia_nyererei
ENSG00000099817	POLR2E	100	95.238	ENSPNAG00000026263	POLR2E	100	95.238	Pygocentrus_nattereri
ENSG00000099817	POLR2E	100	98.571	ENSRNOG00000013545	Polr2e	100	98.571	Rattus_norvegicus
ENSG00000099817	POLR2E	100	73.460	ENSRBIG00000027259	-	100	73.460	Rhinopithecus_bieti
ENSG00000099817	POLR2E	100	99.524	ENSRBIG00000028726	-	100	99.524	Rhinopithecus_bieti
ENSG00000099817	POLR2E	100	99.524	ENSRROG00000043763	POLR2E	100	99.524	Rhinopithecus_roxellana
ENSG00000099817	POLR2E	99	51.515	YBR154C	RPB5	98	43.578	Saccharomyces_cerevisiae
ENSG00000099817	POLR2E	100	99.524	ENSSBOG00000027241	POLR2E	100	99.524	Saimiri_boliviensis_boliviensis
ENSG00000099817	POLR2E	100	99.048	ENSSHAG00000010690	POLR2E	100	99.048	Sarcophilus_harrisii
ENSG00000099817	POLR2E	100	95.238	ENSSFOG00015006073	polr2e	100	95.238	Scleropages_formosus
ENSG00000099817	POLR2E	100	95.238	ENSSMAG00000012782	polr2eb	100	95.238	Scophthalmus_maximus
ENSG00000099817	POLR2E	100	95.238	ENSSDUG00000003352	polr2eb	100	95.238	Seriola_dumerili
ENSG00000099817	POLR2E	100	95.238	ENSSLDG00000004965	polr2eb	100	95.238	Seriola_lalandi_dorsalis
ENSG00000099817	POLR2E	100	97.619	ENSSPUG00000006114	POLR2E	100	97.619	Sphenodon_punctatus
ENSG00000099817	POLR2E	100	95.238	ENSSPAG00000017556	polr2eb	100	95.238	Stegastes_partitus
ENSG00000099817	POLR2E	100	99.524	ENSSSCG00000021472	POLR2E	100	99.524	Sus_scrofa
ENSG00000099817	POLR2E	77	85.106	ENSTGUG00000000922	POLR2E	99	89.286	Taeniopygia_guttata
ENSG00000099817	POLR2E	99	94.737	ENSTRUG00000018238	polr2eb	100	93.989	Takifugu_rubripes
ENSG00000099817	POLR2E	100	95.238	ENSTNIG00000013187	polr2eb	100	95.238	Tetraodon_nigroviridis
ENSG00000099817	POLR2E	100	99.048	ENSTTRG00000001484	POLR2E	100	99.048	Tursiops_truncatus
ENSG00000099817	POLR2E	99	98.361	ENSUAMG00000009166	POLR2E	100	98.361	Ursus_americanus
ENSG00000099817	POLR2E	100	99.524	ENSVVUG00000022818	POLR2E	54	99.524	Vulpes_vulpes
ENSG00000099817	POLR2E	100	97.143	ENSXETG00000003291	polr2e	100	97.143	Xenopus_tropicalis
ENSG00000099817	POLR2E	99	94.536	ENSXCOG00000009197	polr2eb	100	94.536	Xiphophorus_couchianus
ENSG00000099817	POLR2E	100	95.714	ENSXMAG00000026495	polr2eb	100	95.714	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0001054	RNA polymerase I activity	21873635.	IBA	Function
GO:0001055	RNA polymerase II activity	21873635.	IBA	Function
GO:0001056	RNA polymerase III activity	21873635.	IBA	Function
GO:0003677	DNA binding	-	IEA	Function
GO:0003899	DNA-directed 5'-3' RNA polymerase activity	21873635.	IBA	Function
GO:0005515	protein binding	12737519.15923622.	IPI	Function
GO:0005634	nucleus	9852112.	IDA	Component
GO:0005654	nucleoplasm	-	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005665	RNA polymerase II, core complex	21873635.	IBA	Component
GO:0005665	RNA polymerase II, core complex	9852112.	IDA	Component
GO:0005666	RNA polymerase III complex	21873635.	IBA	Component
GO:0005736	RNA polymerase I complex	21873635.	IBA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006283	transcription-coupled nucleotide-excision repair	-	TAS	Process
GO:0006351	transcription, DNA-templated	-	TAS	Process
GO:0006361	transcription initiation from RNA polymerase I promoter	-	TAS	Process
GO:0006362	transcription elongation from RNA polymerase I promoter	-	TAS	Process
GO:0006363	termination of RNA polymerase I transcription	-	TAS	Process
GO:0006366	transcription by RNA polymerase II	9852112.	IDA	Process
GO:0006366	transcription by RNA polymerase II	-	TAS	Process
GO:0006367	transcription initiation from RNA polymerase II promoter	-	TAS	Process
GO:0006368	transcription elongation from RNA polymerase II promoter	-	TAS	Process
GO:0006370	7-methylguanosine mRNA capping	-	TAS	Process
GO:0006383	transcription by RNA polymerase III	-	IEA	Process
GO:0008543	fibroblast growth factor receptor signaling pathway	-	TAS	Process
GO:0016032	viral process	-	IEA	Process
GO:0016070	RNA metabolic process	-	TAS	Process
GO:0032481	positive regulation of type I interferon production	-	TAS	Process
GO:0035019	somatic stem cell population maintenance	-	TAS	Process
GO:0042795	snRNA transcription by RNA polymerase II	-	TAS	Process
GO:0045815	positive regulation of gene expression, epigenetic	-	TAS	Process
GO:0050434	positive regulation of viral transcription	-	TAS	Process
GO:0060964	regulation of gene silencing by miRNA	-	TAS	Process