EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000099860 (Gene tree)
Gene ID: 4616
Gene Symbol: GADD45B
Alias: GADD45BETA|DKFZP566B133|MYD118
Full Name: growth arrest and DNA damage inducible beta
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 2,138 bases
Position: chr19:2,476,122-2,478,259
Accession: 4096
RBP type: canonical RBP
Summary: This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The genes in this group respond to environmental stresses by mediating activation of the p38/JNK pathway. This activation is mediated via their proteins binding and activating MTK1/MEKK4 kinase, which is an upstream activator of both p38 and JNK MAPKs. The function of these genes or their protein products is involved in the regulation of growth and apoptosis. These genes are regulated by different mechanisms, but they are often coordinately expressed and can function cooperatively in inhibiting cell growth. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000215631	Ribosomal_L7Ae	PF01248.26	6.6e-18	1	1
ENSP00000467490	Ribosomal_L7Ae	PF01248.26	1.4e-17	1	1
ENSP00000468374	Ribosomal_L7Ae	PF01248.26	7.6e-08	1	1
ENSP00000468620	Ribosomal_L7Ae	PF01248.26	7.6e-08	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
28841715	Nuclease escape elements protect messenger RNA against cleavage by multiple viral endonucleases.	PLoS Pathog	2017 Aug 25	Muller M	doi: 10.1371/journal.ppat.1006593
31074668	Pretreatment with Salvia miltiorrhiza Polysaccharides Protects from Lipopolysaccharides/d-Galactosamine-Induced Liver Injury in Mice through Inhibiting TLR4/MyD88 Signaling Pathway.	J Interferon Cytokine Res	2019 May 10	Wang X	doi: 10.1089/jir.2018.0137
14703492	[Construction of subtracted cDNA library in human Jurkat T cell line induced by arsenic trioxide in vitro].	Zhonghua Yu Fang Yi Xue Za Zhi	2003 Nov	Zhang YX	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000215631	GADD45B-201	1373	-	ENSP00000215631	160 (aa)	-	O75293
ENST00000592937	GADD45B-206	2007	-	-	- (aa)	-	-
ENST00000587887	GADD45B-205	276	-	ENSP00000468620	66 (aa)	-	Q6IX74
ENST00000585359	GADD45B-202	750	-	ENSP00000466414	60 (aa)	-	K7EM97
ENST00000586759	GADD45B-203	517	-	-	- (aa)	-	-
ENST00000593043	GADD45B-207	373	-	ENSP00000468374	66 (aa)	-	Q6IX74
ENST00000587345	GADD45B-204	765	XM_017026822	ENSP00000467490	176 (aa)	XP_016882311	K7EPQ8

Gene Model

Click here to download ENSG00000099860's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa04010	MAPK signaling pathway	KEGG
hsa04064	NF-kappa B signaling pathway	KEGG
hsa04068	FoxO signaling pathway	KEGG
hsa04110	Cell cycle	KEGG
hsa04115	p53 signaling pathway	KEGG
hsa04210	Apoptosis	KEGG
hsa04218	Cellular senescence	KEGG
hsa05169	Epstein-Barr virus infection	KEGG
hsa05200	Pathways in cancer	KEGG
hsa05202	Transcriptional misregulation in cancer	KEGG
hsa05210	Colorectal cancer	KEGG
hsa05212	Pancreatic cancer	KEGG
hsa05213	Endometrial cancer	KEGG
hsa05214	Glioma	KEGG
hsa05216	Thyroid cancer	KEGG
hsa05217	Basal cell carcinoma	KEGG
hsa05218	Melanoma	KEGG
hsa05220	Chronic myeloid leukemia	KEGG
hsa05222	Small cell lung cancer	KEGG
hsa05223	Non-small cell lung cancer	KEGG
hsa05224	Breast cancer	KEGG
hsa05225	Hepatocellular carcinoma	KEGG
hsa05226	Gastric cancer	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000099860	Platelet Function Tests	2.7700000E-006	-

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000099860's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000099860	GADD45B	100	84.848	ENSAPOG00000012789	gadd45bb	100	68.125	Acanthochromis_polyacanthus
ENSG00000099860	GADD45B	91	73.333	ENSAPOG00000018531	-	100	56.250	Acanthochromis_polyacanthus
ENSG00000099860	GADD45B	100	74.242	ENSAPOG00000001477	-	92	63.014	Acanthochromis_polyacanthus
ENSG00000099860	GADD45B	100	68.182	ENSAPOG00000018522	-	100	59.310	Acanthochromis_polyacanthus
ENSG00000099860	GADD45B	100	66.667	ENSAPOG00000015769	gadd45ab	100	55.625	Acanthochromis_polyacanthus
ENSG00000099860	GADD45B	100	75.758	ENSAPOG00000017050	gadd45ga	100	57.669	Acanthochromis_polyacanthus
ENSG00000099860	GADD45B	100	63.636	ENSAPOG00000014659	gadd45aa	98	53.049	Acanthochromis_polyacanthus
ENSG00000099860	GADD45B	71	54.867	ENSAMEG00000003453	GADD45G	80	54.867	Ailuropoda_melanoleuca
ENSG00000099860	GADD45B	100	65.152	ENSAMEG00000004529	GADD45A	100	55.758	Ailuropoda_melanoleuca
ENSG00000099860	GADD45B	100	95.000	ENSAMEG00000005608	GADD45B	100	95.000	Ailuropoda_melanoleuca
ENSG00000099860	GADD45B	98	70.769	ENSACIG00000018053	-	87	63.194	Amphilophus_citrinellus
ENSG00000099860	GADD45B	91	48.333	ENSACIG00000006435	-	84	37.324	Amphilophus_citrinellus
ENSG00000099860	GADD45B	100	62.121	ENSACIG00000006400	-	99	53.378	Amphilophus_citrinellus
ENSG00000099860	GADD45B	100	68.182	ENSACIG00000009153	-	100	54.601	Amphilophus_citrinellus
ENSG00000099860	GADD45B	100	72.727	ENSACIG00000003856	gadd45ga	100	57.055	Amphilophus_citrinellus
ENSG00000099860	GADD45B	100	81.818	ENSACIG00000006455	gadd45bb	100	68.750	Amphilophus_citrinellus
ENSG00000099860	GADD45B	100	62.121	ENSACIG00000021153	gadd45aa	100	53.416	Amphilophus_citrinellus
ENSG00000099860	GADD45B	100	65.152	ENSACIG00000015677	gadd45ab	100	54.375	Amphilophus_citrinellus
ENSG00000099860	GADD45B	98	69.231	ENSACIG00000009254	-	100	56.250	Amphilophus_citrinellus
ENSG00000099860	GADD45B	97	67.188	ENSAOCG00000015489	-	88	59.712	Amphiprion_ocellaris
ENSG00000099860	GADD45B	100	75.758	ENSAOCG00000018886	gadd45ga	100	57.669	Amphiprion_ocellaris
ENSG00000099860	GADD45B	100	63.636	ENSAOCG00000007802	GADD45A	98	53.704	Amphiprion_ocellaris
ENSG00000099860	GADD45B	100	84.848	ENSAOCG00000006111	gadd45bb	100	68.750	Amphiprion_ocellaris
ENSG00000099860	GADD45B	91	73.333	ENSAOCG00000002770	-	100	55.625	Amphiprion_ocellaris
ENSG00000099860	GADD45B	100	65.152	ENSAOCG00000007893	gadd45ab	100	54.375	Amphiprion_ocellaris
ENSG00000099860	GADD45B	100	63.636	ENSAOCG00000019928	gadd45aa	98	53.704	Amphiprion_ocellaris
ENSG00000099860	GADD45B	100	84.848	ENSAPEG00000000894	gadd45bb	100	68.750	Amphiprion_percula
ENSG00000099860	GADD45B	91	73.333	ENSAPEG00000019619	-	100	55.625	Amphiprion_percula
ENSG00000099860	GADD45B	100	63.636	ENSAPEG00000015036	gadd45aa	100	53.704	Amphiprion_percula
ENSG00000099860	GADD45B	100	75.758	ENSAPEG00000006185	gadd45ga	100	57.669	Amphiprion_percula
ENSG00000099860	GADD45B	86	75.439	ENSAPEG00000019595	-	82	61.029	Amphiprion_percula
ENSG00000099860	GADD45B	100	65.152	ENSAPEG00000023576	gadd45ab	100	54.375	Amphiprion_percula
ENSG00000099860	GADD45B	100	62.121	ENSATEG00000018860	gadd45aa	98	54.658	Anabas_testudineus
ENSG00000099860	GADD45B	100	68.182	ENSATEG00000004993	-	91	56.757	Anabas_testudineus
ENSG00000099860	GADD45B	98	67.692	ENSATEG00000005086	-	100	56.250	Anabas_testudineus
ENSG00000099860	GADD45B	100	65.152	ENSATEG00000008812	gadd45ab	100	55.000	Anabas_testudineus
ENSG00000099860	GADD45B	100	71.212	ENSATEG00000008132	-	99	58.228	Anabas_testudineus
ENSG00000099860	GADD45B	100	75.758	ENSATEG00000017274	gadd45ga	100	58.896	Anabas_testudineus
ENSG00000099860	GADD45B	100	86.364	ENSATEG00000005592	gadd45bb	100	68.750	Anabas_testudineus
ENSG00000099860	GADD45B	100	66.667	ENSACAG00000012182	GADD45G	85	59.184	Anolis_carolinensis
ENSG00000099860	GADD45B	100	66.667	ENSACAG00000011832	GADD45A	100	58.125	Anolis_carolinensis
ENSG00000099860	GADD45B	100	99.375	ENSANAG00000033393	GADD45B	100	99.375	Aotus_nancymaae
ENSG00000099860	GADD45B	100	65.152	ENSANAG00000024828	GADD45A	100	55.758	Aotus_nancymaae
ENSG00000099860	GADD45B	100	68.182	ENSANAG00000021164	GADD45G	100	55.556	Aotus_nancymaae
ENSG00000099860	GADD45B	100	60.606	ENSACLG00000002727	-	98	52.229	Astatotilapia_calliptera
ENSG00000099860	GADD45B	100	65.152	ENSACLG00000026739	gadd45ab	93	55.479	Astatotilapia_calliptera
ENSG00000099860	GADD45B	91	48.333	ENSACLG00000002817	-	83	38.298	Astatotilapia_calliptera
ENSG00000099860	GADD45B	98	69.231	ENSACLG00000027709	-	100	56.250	Astatotilapia_calliptera
ENSG00000099860	GADD45B	100	66.667	ENSACLG00000027707	-	100	57.931	Astatotilapia_calliptera
ENSG00000099860	GADD45B	100	65.152	ENSACLG00000008451	gadd45aa	100	56.849	Astatotilapia_calliptera
ENSG00000099860	GADD45B	100	83.333	ENSACLG00000002682	gadd45bb	100	68.125	Astatotilapia_calliptera
ENSG00000099860	GADD45B	100	74.242	ENSACLG00000014490	gadd45ga	100	57.055	Astatotilapia_calliptera
ENSG00000099860	GADD45B	100	72.727	ENSACLG00000009408	-	66	61.644	Astatotilapia_calliptera
ENSG00000099860	GADD45B	100	83.333	ENSAMXG00000036454	gadd45ba	100	67.059	Astyanax_mexicanus
ENSG00000099860	GADD45B	100	69.697	ENSAMXG00000043110	-	100	56.250	Astyanax_mexicanus
ENSG00000099860	GADD45B	100	62.121	ENSAMXG00000009080	gadd45gb.1	100	53.103	Astyanax_mexicanus
ENSG00000099860	GADD45B	100	68.182	ENSAMXG00000005863	gadd45ga	100	55.280	Astyanax_mexicanus
ENSG00000099860	GADD45B	100	65.152	ENSAMXG00000039299	gadd45ab	98	56.250	Astyanax_mexicanus
ENSG00000099860	GADD45B	100	62.121	ENSAMXG00000039081	gadd45aa	100	49.390	Astyanax_mexicanus
ENSG00000099860	GADD45B	100	96.970	ENSBTAG00000025462	GADD45B	100	96.875	Bos_taurus
ENSG00000099860	GADD45B	100	65.152	ENSBTAG00000013860	GADD45A	100	55.152	Bos_taurus
ENSG00000099860	GADD45B	100	68.182	ENSBTAG00000003033	GADD45G	59	56.173	Bos_taurus
ENSG00000099860	GADD45B	100	98.485	ENSCJAG00000013616	GADD45B	100	96.875	Callithrix_jacchus
ENSG00000099860	GADD45B	100	68.182	ENSCJAG00000045850	GADD45G	100	55.556	Callithrix_jacchus
ENSG00000099860	GADD45B	100	65.152	ENSCJAG00000017502	GADD45A	100	55.152	Callithrix_jacchus
ENSG00000099860	GADD45B	100	98.485	ENSCAFG00000019386	GADD45B	100	98.125	Canis_familiaris
ENSG00000099860	GADD45B	100	66.667	ENSCAFG00000002174	GADD45G	100	54.938	Canis_familiaris
ENSG00000099860	GADD45B	100	65.152	ENSCAFG00000029474	GADD45A	100	55.152	Canis_familiaris
ENSG00000099860	GADD45B	100	65.152	ENSCAFG00020017438	GADD45A	100	55.152	Canis_lupus_dingo
ENSG00000099860	GADD45B	100	98.485	ENSCAFG00020018199	GADD45B	100	98.125	Canis_lupus_dingo
ENSG00000099860	GADD45B	100	66.667	ENSCAFG00020007172	GADD45G	100	54.938	Canis_lupus_dingo
ENSG00000099860	GADD45B	100	98.485	ENSCHIG00000011819	GADD45B	100	98.125	Capra_hircus
ENSG00000099860	GADD45B	100	68.182	ENSCHIG00000016621	GADD45G	100	55.556	Capra_hircus
ENSG00000099860	GADD45B	100	65.152	ENSCHIG00000025537	GADD45A	100	55.152	Capra_hircus
ENSG00000099860	GADD45B	100	66.667	ENSCPOG00000005810	GADD45A	100	56.790	Cavia_porcellus
ENSG00000099860	GADD45B	100	100.000	ENSCPOG00000034176	GADD45B	100	94.375	Cavia_porcellus
ENSG00000099860	GADD45B	92	65.574	ENSCPOG00000013394	GADD45G	85	52.980	Cavia_porcellus
ENSG00000099860	GADD45B	100	68.182	ENSCCAG00000035443	GADD45G	100	55.556	Cebus_capucinus
ENSG00000099860	GADD45B	100	100.000	ENSCCAG00000023859	GADD45B	100	100.000	Cebus_capucinus
ENSG00000099860	GADD45B	100	65.152	ENSCCAG00000037220	GADD45A	100	55.758	Cebus_capucinus
ENSG00000099860	GADD45B	100	100.000	ENSCATG00000039400	GADD45B	100	99.375	Cercocebus_atys
ENSG00000099860	GADD45B	100	68.182	ENSCATG00000041187	GADD45G	100	55.556	Cercocebus_atys
ENSG00000099860	GADD45B	100	65.152	ENSCATG00000040913	GADD45A	100	56.364	Cercocebus_atys
ENSG00000099860	GADD45B	100	96.970	ENSCLAG00000008923	GADD45B	100	93.750	Chinchilla_lanigera
ENSG00000099860	GADD45B	100	68.182	ENSCLAG00000000922	GADD45G	100	56.173	Chinchilla_lanigera
ENSG00000099860	GADD45B	67	56.881	ENSCLAG00000007279	GADD45A	100	56.881	Chinchilla_lanigera
ENSG00000099860	GADD45B	100	66.667	ENSCSAG00000007287	GADD45G	100	54.938	Chlorocebus_sabaeus
ENSG00000099860	GADD45B	100	100.000	ENSCSAG00000011516	GADD45B	100	99.375	Chlorocebus_sabaeus
ENSG00000099860	GADD45B	100	65.152	ENSCSAG00000001366	GADD45A	100	55.758	Chlorocebus_sabaeus
ENSG00000099860	GADD45B	100	66.667	ENSCHOG00000007482	GADD45G	100	59.551	Choloepus_hoffmanni
ENSG00000099860	GADD45B	68	87.156	ENSCHOG00000010573	GADD45B	99	87.156	Choloepus_hoffmanni
ENSG00000099860	GADD45B	65	74.419	ENSCHOG00000008456	GADD45A	77	57.812	Choloepus_hoffmanni
ENSG00000099860	GADD45B	100	69.697	ENSCPBG00000001491	GADD45A	100	60.000	Chrysemys_picta_bellii
ENSG00000099860	GADD45B	100	69.697	ENSCPBG00000005658	GADD45G	100	57.407	Chrysemys_picta_bellii
ENSG00000099860	GADD45B	100	87.879	ENSCPBG00000012367	GADD45B	100	82.500	Chrysemys_picta_bellii
ENSG00000099860	GADD45B	100	100.000	ENSCANG00000029710	GADD45B	100	99.375	Colobus_angolensis_palliatus
ENSG00000099860	GADD45B	100	65.152	ENSCANG00000041985	GADD45A	100	55.152	Colobus_angolensis_palliatus
ENSG00000099860	GADD45B	100	68.182	ENSCANG00000034521	GADD45G	100	62.366	Colobus_angolensis_palliatus
ENSG00000099860	GADD45B	100	66.667	ENSCGRG00001022826	GADD45A	100	56.970	Cricetulus_griseus_chok1gshd
ENSG00000099860	GADD45B	100	95.455	ENSCGRG00001024479	Gadd45b	100	93.750	Cricetulus_griseus_chok1gshd
ENSG00000099860	GADD45B	100	68.182	ENSCGRG00001021226	Gadd45g	100	54.938	Cricetulus_griseus_chok1gshd
ENSG00000099860	GADD45B	100	68.182	ENSCGRG00000002489	Gadd45g	100	54.938	Cricetulus_griseus_crigri
ENSG00000099860	GADD45B	100	95.455	ENSCGRG00000004613	Gadd45b	100	93.750	Cricetulus_griseus_crigri
ENSG00000099860	GADD45B	98	69.231	ENSCSEG00000003573	-	92	58.904	Cynoglossus_semilaevis
ENSG00000099860	GADD45B	100	74.242	ENSCSEG00000009227	-	100	57.669	Cynoglossus_semilaevis
ENSG00000099860	GADD45B	100	65.152	ENSCSEG00000016792	-	100	53.793	Cynoglossus_semilaevis
ENSG00000099860	GADD45B	100	62.121	ENSCSEG00000017865	gadd45aa	100	54.658	Cynoglossus_semilaevis
ENSG00000099860	GADD45B	100	71.212	ENSCSEG00000017525	gadd45ga	100	56.442	Cynoglossus_semilaevis
ENSG00000099860	GADD45B	100	78.788	ENSCSEG00000000436	GADD45B	96	63.125	Cynoglossus_semilaevis
ENSG00000099860	GADD45B	86	73.684	ENSCVAG00000022212	-	82	61.029	Cyprinodon_variegatus
ENSG00000099860	GADD45B	100	63.636	ENSCVAG00000012278	gadd45ab	100	49.375	Cyprinodon_variegatus
ENSG00000099860	GADD45B	100	74.242	ENSCVAG00000011001	gadd45ga	100	58.282	Cyprinodon_variegatus
ENSG00000099860	GADD45B	100	65.152	ENSCVAG00000004457	GADD45A	98	56.250	Cyprinodon_variegatus
ENSG00000099860	GADD45B	98	69.231	ENSCVAG00000022230	-	100	57.500	Cyprinodon_variegatus
ENSG00000099860	GADD45B	100	86.364	ENSCVAG00000012528	gadd45bb	99	69.811	Cyprinodon_variegatus
ENSG00000099860	GADD45B	100	69.697	ENSCVAG00000013417	-	100	59.375	Cyprinodon_variegatus
ENSG00000099860	GADD45B	100	78.788	ENSDARG00000013576	gadd45bb	100	69.565	Danio_rerio
ENSG00000099860	GADD45B	100	66.667	ENSDARG00000104571	gadd45ab	100	57.500	Danio_rerio
ENSG00000099860	GADD45B	100	60.606	ENSDARG00000043581	gadd45aa	100	55.000	Danio_rerio
ENSG00000099860	GADD45B	100	74.242	ENSDARG00000019417	gadd45ga	100	58.282	Danio_rerio
ENSG00000099860	GADD45B	97	68.750	ENSDARG00000016725	gadd45gb.1	100	54.375	Danio_rerio
ENSG00000099860	GADD45B	100	81.818	ENSDARG00000027744	gadd45ba	100	68.750	Danio_rerio
ENSG00000099860	GADD45B	100	86.364	ENSDNOG00000023662	GADD45B	100	89.247	Dasypus_novemcinctus
ENSG00000099860	GADD45B	100	68.182	ENSDNOG00000009368	GADD45G	100	54.938	Dasypus_novemcinctus
ENSG00000099860	GADD45B	100	65.152	ENSDNOG00000038488	GADD45A	100	55.758	Dasypus_novemcinctus
ENSG00000099860	GADD45B	100	98.485	ENSDORG00000025421	Gadd45b	100	94.375	Dipodomys_ordii
ENSG00000099860	GADD45B	100	65.152	ENSDORG00000011668	-	100	54.819	Dipodomys_ordii
ENSG00000099860	GADD45B	100	66.667	ENSDORG00000012168	Gadd45g	100	54.321	Dipodomys_ordii
ENSG00000099860	GADD45B	69	55.455	ENSETEG00000012115	GADD45G	100	44.444	Echinops_telfairi
ENSG00000099860	GADD45B	100	96.970	ENSETEG00000004478	GADD45B	100	91.250	Echinops_telfairi
ENSG00000099860	GADD45B	86	66.667	ENSETEG00000001297	GADD45A	100	55.469	Echinops_telfairi
ENSG00000099860	GADD45B	91	71.667	ENSEBUG00000001643	-	86	53.086	Eptatretus_burgeri
ENSG00000099860	GADD45B	100	55.224	ENSEBUG00000013807	gadd45aa	100	43.827	Eptatretus_burgeri
ENSG00000099860	GADD45B	91	71.667	ENSEBUG00000008240	-	100	52.174	Eptatretus_burgeri
ENSG00000099860	GADD45B	100	68.182	ENSEASG00005013974	GADD45G	100	54.938	Equus_asinus_asinus
ENSG00000099860	GADD45B	100	65.152	ENSEASG00005007877	GADD45A	100	55.758	Equus_asinus_asinus
ENSG00000099860	GADD45B	100	99.375	ENSEASG00005022021	GADD45B	100	99.375	Equus_asinus_asinus
ENSG00000099860	GADD45B	100	65.152	ENSECAG00000040631	GADD45A	100	55.758	Equus_caballus
ENSG00000099860	GADD45B	100	66.667	ENSECAG00000023399	GADD45G	100	54.321	Equus_caballus
ENSG00000099860	GADD45B	100	99.375	ENSECAG00000009168	GADD45B	74	99.375	Equus_caballus
ENSG00000099860	GADD45B	100	84.848	ENSELUG00000001451	gadd45ba	100	69.753	Esox_lucius
ENSG00000099860	GADD45B	91	75.000	ENSELUG00000011823	-	100	55.000	Esox_lucius
ENSG00000099860	GADD45B	100	65.152	ENSELUG00000011831	-	99	55.479	Esox_lucius
ENSG00000099860	GADD45B	100	63.636	ENSELUG00000019370	gadd45aa	98	55.000	Esox_lucius
ENSG00000099860	GADD45B	100	63.636	ENSELUG00000002845	gadd45ab	98	53.125	Esox_lucius
ENSG00000099860	GADD45B	100	71.212	ENSELUG00000002447	gadd45g	91	57.333	Esox_lucius
ENSG00000099860	GADD45B	100	99.187	ENSFCAG00000013046	GADD45B	66	99.187	Felis_catus
ENSG00000099860	GADD45B	100	68.182	ENSFCAG00000045577	GADD45G	100	55.556	Felis_catus
ENSG00000099860	GADD45B	100	65.152	ENSFCAG00000002987	GADD45A	100	55.758	Felis_catus
ENSG00000099860	GADD45B	88	87.931	ENSFALG00000002655	GADD45B	100	71.875	Ficedula_albicollis
ENSG00000099860	GADD45B	100	69.697	ENSFALG00000004751	GADD45G	100	56.173	Ficedula_albicollis
ENSG00000099860	GADD45B	100	68.182	ENSFDAG00000021114	GADD45G	100	55.556	Fukomys_damarensis
ENSG00000099860	GADD45B	100	71.212	ENSFHEG00000009822	-	100	59.375	Fundulus_heteroclitus
ENSG00000099860	GADD45B	100	63.636	ENSFHEG00000014191	gadd45ab	72	52.500	Fundulus_heteroclitus
ENSG00000099860	GADD45B	100	74.242	ENSFHEG00000018235	gadd45ga	100	57.669	Fundulus_heteroclitus
ENSG00000099860	GADD45B	100	86.364	ENSFHEG00000002520	gadd45bb	99	69.182	Fundulus_heteroclitus
ENSG00000099860	GADD45B	100	65.217	ENSFHEG00000014938	-	87	56.000	Fundulus_heteroclitus
ENSG00000099860	GADD45B	98	67.692	ENSFHEG00000014954	-	100	56.250	Fundulus_heteroclitus
ENSG00000099860	GADD45B	100	63.636	ENSFHEG00000017986	gadd45aa	98	55.625	Fundulus_heteroclitus
ENSG00000099860	GADD45B	98	69.231	ENSGMOG00000010053	-	100	56.489	Gadus_morhua
ENSG00000099860	GADD45B	100	71.212	ENSGMOG00000007651	gadd45ga	100	55.215	Gadus_morhua
ENSG00000099860	GADD45B	100	63.636	ENSGMOG00000017094	gadd45aa	100	53.704	Gadus_morhua
ENSG00000099860	GADD45B	100	63.636	ENSGMOG00000007698	gadd45ab	94	55.705	Gadus_morhua
ENSG00000099860	GADD45B	100	65.152	ENSGMOG00000010057	-	89	56.164	Gadus_morhua
ENSG00000099860	GADD45B	100	75.758	ENSGALG00000029968	GADD45B	85	72.109	Gallus_gallus
ENSG00000099860	GADD45B	100	68.182	ENSGALG00000025977	GADD45A	100	58.750	Gallus_gallus
ENSG00000099860	GADD45B	100	71.212	ENSGALG00000028005	GADD45G	89	61.111	Gallus_gallus
ENSG00000099860	GADD45B	100	65.152	ENSGAFG00000016554	gadd45ab	72	53.125	Gambusia_affinis
ENSG00000099860	GADD45B	100	74.242	ENSGAFG00000012217	gadd45ga	100	58.282	Gambusia_affinis
ENSG00000099860	GADD45B	100	71.212	ENSGAFG00000019140	-	92	61.644	Gambusia_affinis
ENSG00000099860	GADD45B	100	62.121	ENSGAFG00000017341	gadd45aa	98	53.750	Gambusia_affinis
ENSG00000099860	GADD45B	100	87.879	ENSGAFG00000011541	gadd45bb	99	70.440	Gambusia_affinis
ENSG00000099860	GADD45B	100	60.606	ENSGACG00000015621	gadd45aa	100	55.280	Gasterosteus_aculeatus
ENSG00000099860	GADD45B	100	72.727	ENSGACG00000006793	gadd45ga	100	55.758	Gasterosteus_aculeatus
ENSG00000099860	GADD45B	98	66.154	ENSGACG00000010706	-	91	57.718	Gasterosteus_aculeatus
ENSG00000099860	GADD45B	98	67.692	ENSGACG00000017938	-	100	54.375	Gasterosteus_aculeatus
ENSG00000099860	GADD45B	100	83.333	ENSGACG00000013618	gadd45bb	100	66.250	Gasterosteus_aculeatus
ENSG00000099860	GADD45B	100	63.636	ENSGACG00000004068	gadd45ab	100	55.625	Gasterosteus_aculeatus
ENSG00000099860	GADD45B	100	62.121	ENSGACG00000017943	-	88	53.793	Gasterosteus_aculeatus
ENSG00000099860	GADD45B	100	89.394	ENSGAGG00000013645	GADD45B	100	82.500	Gopherus_agassizii
ENSG00000099860	GADD45B	100	65.152	ENSGAGG00000011459	GADD45A	100	57.500	Gopherus_agassizii
ENSG00000099860	GADD45B	100	69.697	ENSGAGG00000023952	GADD45G	100	57.407	Gopherus_agassizii
ENSG00000099860	GADD45B	100	100.000	ENSGGOG00000028478	GADD45B	100	100.000	Gorilla_gorilla
ENSG00000099860	GADD45B	100	65.152	ENSGGOG00000010780	GADD45A	100	55.758	Gorilla_gorilla
ENSG00000099860	GADD45B	100	68.182	ENSGGOG00000005045	GADD45G	100	55.556	Gorilla_gorilla
ENSG00000099860	GADD45B	100	66.667	ENSHBUG00000012472	-	100	57.931	Haplochromis_burtoni
ENSG00000099860	GADD45B	100	65.152	ENSHBUG00000007603	gadd45aa	100	56.849	Haplochromis_burtoni
ENSG00000099860	GADD45B	100	72.727	ENSHBUG00000008113	-	92	62.329	Haplochromis_burtoni
ENSG00000099860	GADD45B	100	74.242	ENSHBUG00000003848	gadd45ga	100	57.055	Haplochromis_burtoni
ENSG00000099860	GADD45B	100	65.152	ENSHBUG00000011301	gadd45ab	93	55.479	Haplochromis_burtoni
ENSG00000099860	GADD45B	100	83.333	ENSHBUG00000012913	gadd45bb	100	68.750	Haplochromis_burtoni
ENSG00000099860	GADD45B	100	59.091	ENSHBUG00000021375	-	92	52.414	Haplochromis_burtoni
ENSG00000099860	GADD45B	98	69.231	ENSHBUG00000012482	-	100	56.250	Haplochromis_burtoni
ENSG00000099860	GADD45B	100	100.000	ENSHGLG00000015117	GADD45B	100	96.875	Heterocephalus_glaber_female
ENSG00000099860	GADD45B	100	66.667	ENSHGLG00000004470	GADD45A	100	56.790	Heterocephalus_glaber_female
ENSG00000099860	GADD45B	100	68.182	ENSHGLG00000006188	GADD45G	100	56.098	Heterocephalus_glaber_female
ENSG00000099860	GADD45B	100	100.000	ENSHGLG00100014393	GADD45B	100	96.250	Heterocephalus_glaber_male
ENSG00000099860	GADD45B	100	68.182	ENSHGLG00100004156	GADD45G	100	56.098	Heterocephalus_glaber_male
ENSG00000099860	GADD45B	91	70.000	ENSHCOG00000015442	-	97	53.049	Hippocampus_comes
ENSG00000099860	GADD45B	100	69.697	ENSHCOG00000013991	gadd45ga	100	54.601	Hippocampus_comes
ENSG00000099860	GADD45B	100	60.606	ENSHCOG00000016830	gadd45aa	100	54.375	Hippocampus_comes
ENSG00000099860	GADD45B	100	65.152	ENSHCOG00000011985	-	66	58.559	Hippocampus_comes
ENSG00000099860	GADD45B	91	71.667	ENSHCOG00000012028	-	99	53.416	Hippocampus_comes
ENSG00000099860	GADD45B	100	65.152	ENSIPUG00000011743	gadd45ab	75	55.000	Ictalurus_punctatus
ENSG00000099860	GADD45B	100	62.121	ENSIPUG00000021521	gadd45ga	100	49.697	Ictalurus_punctatus
ENSG00000099860	GADD45B	98	69.231	ENSIPUG00000004791	GADD45G	100	52.500	Ictalurus_punctatus
ENSG00000099860	GADD45B	100	63.636	ENSIPUG00000013944	GADD45A	100	55.000	Ictalurus_punctatus
ENSG00000099860	GADD45B	100	83.333	ENSIPUG00000007624	gadd45b	68	67.901	Ictalurus_punctatus
ENSG00000099860	GADD45B	53	77.143	ENSIPUG00000004787	-	98	53.153	Ictalurus_punctatus
ENSG00000099860	GADD45B	98	66.154	ENSIPUG00000014145	-	100	52.174	Ictalurus_punctatus
ENSG00000099860	GADD45B	100	100.000	ENSSTOG00000027321	GADD45B	100	95.625	Ictidomys_tridecemlineatus
ENSG00000099860	GADD45B	100	69.697	ENSSTOG00000027370	GADD45G	100	57.407	Ictidomys_tridecemlineatus
ENSG00000099860	GADD45B	100	65.152	ENSSTOG00000024503	GADD45A	100	56.364	Ictidomys_tridecemlineatus
ENSG00000099860	GADD45B	100	95.455	ENSJJAG00000020166	Gadd45b	100	93.750	Jaculus_jaculus
ENSG00000099860	GADD45B	100	66.667	ENSJJAG00000000083	Gadd45g	100	54.321	Jaculus_jaculus
ENSG00000099860	GADD45B	100	65.152	ENSJJAG00000016764	Gadd45a	100	55.422	Jaculus_jaculus
ENSG00000099860	GADD45B	97	70.312	ENSKMAG00000013838	-	92	55.034	Kryptolebias_marmoratus
ENSG00000099860	GADD45B	98	63.077	ENSKMAG00000002882	gadd45gb.1	100	53.125	Kryptolebias_marmoratus
ENSG00000099860	GADD45B	100	62.121	ENSKMAG00000001788	gadd45aa	98	54.375	Kryptolebias_marmoratus
ENSG00000099860	GADD45B	100	74.242	ENSKMAG00000022252	gadd45ga	100	58.282	Kryptolebias_marmoratus
ENSG00000099860	GADD45B	100	87.879	ENSKMAG00000018171	gadd45bb	100	70.345	Kryptolebias_marmoratus
ENSG00000099860	GADD45B	100	60.606	ENSKMAG00000004181	gadd45ab	100	52.500	Kryptolebias_marmoratus
ENSG00000099860	GADD45B	100	62.121	ENSLBEG00000005962	gadd45aa	98	54.037	Labrus_bergylta
ENSG00000099860	GADD45B	100	83.333	ENSLBEG00000004816	gadd45bb	100	67.500	Labrus_bergylta
ENSG00000099860	GADD45B	100	71.212	ENSLBEG00000022030	-	93	60.959	Labrus_bergylta
ENSG00000099860	GADD45B	100	71.212	ENSLBEG00000004255	gadd45ga	100	55.828	Labrus_bergylta
ENSG00000099860	GADD45B	100	68.182	ENSLBEG00000017680	-	100	58.621	Labrus_bergylta
ENSG00000099860	GADD45B	98	69.231	ENSLBEG00000017658	-	100	56.875	Labrus_bergylta
ENSG00000099860	GADD45B	100	63.636	ENSLBEG00000000664	gadd45ab	100	52.500	Labrus_bergylta
ENSG00000099860	GADD45B	100	84.848	ENSLACG00000009526	GADD45B	100	76.250	Latimeria_chalumnae
ENSG00000099860	GADD45B	100	71.212	ENSLACG00000004429	GADD45G	100	58.282	Latimeria_chalumnae
ENSG00000099860	GADD45B	100	60.606	ENSLACG00000003888	GADD45A	100	55.625	Latimeria_chalumnae
ENSG00000099860	GADD45B	100	65.152	ENSLOCG00000008149	-	78	51.875	Lepisosteus_oculatus
ENSG00000099860	GADD45B	100	65.152	ENSLOCG00000004532	gadd45aa	98	60.000	Lepisosteus_oculatus
ENSG00000099860	GADD45B	100	83.333	ENSLOCG00000000752	gadd45ba	100	75.000	Lepisosteus_oculatus
ENSG00000099860	GADD45B	100	68.182	ENSLAFG00000027458	GADD45G	100	54.938	Loxodonta_africana
ENSG00000099860	GADD45B	92	55.738	ENSLAFG00000009362	GADD45A	93	56.618	Loxodonta_africana
ENSG00000099860	GADD45B	100	96.970	ENSLAFG00000016948	GADD45B	100	95.625	Loxodonta_africana
ENSG00000099860	GADD45B	100	100.000	ENSMFAG00000042254	GADD45B	100	99.375	Macaca_fascicularis
ENSG00000099860	GADD45B	100	68.182	ENSMFAG00000039291	GADD45G	100	55.556	Macaca_fascicularis
ENSG00000099860	GADD45B	100	65.152	ENSMFAG00000043026	GADD45A	100	56.364	Macaca_fascicularis
ENSG00000099860	GADD45B	100	65.152	ENSMMUG00000038425	GADD45A	100	58.000	Macaca_mulatta
ENSG00000099860	GADD45B	100	100.000	ENSMMUG00000003468	GADD45B	100	99.375	Macaca_mulatta
ENSG00000099860	GADD45B	100	68.182	ENSMMUG00000048737	GADD45G	100	55.556	Macaca_mulatta
ENSG00000099860	GADD45B	100	100.000	ENSMNEG00000038733	GADD45B	100	99.375	Macaca_nemestrina
ENSG00000099860	GADD45B	100	68.182	ENSMNEG00000042753	GADD45G	100	55.556	Macaca_nemestrina
ENSG00000099860	GADD45B	100	65.152	ENSMNEG00000028909	GADD45A	100	56.364	Macaca_nemestrina
ENSG00000099860	GADD45B	100	100.000	ENSMLEG00000036112	GADD45B	100	99.375	Mandrillus_leucophaeus
ENSG00000099860	GADD45B	100	65.152	ENSMLEG00000033790	GADD45A	100	56.364	Mandrillus_leucophaeus
ENSG00000099860	GADD45B	100	68.182	ENSMLEG00000031770	GADD45G	100	55.556	Mandrillus_leucophaeus
ENSG00000099860	GADD45B	100	63.636	ENSMAMG00000007791	gadd45ab	100	53.750	Mastacembelus_armatus
ENSG00000099860	GADD45B	100	68.182	ENSMAMG00000000657	-	96	58.621	Mastacembelus_armatus
ENSG00000099860	GADD45B	100	75.758	ENSMAMG00000020783	gadd45ga	100	58.896	Mastacembelus_armatus
ENSG00000099860	GADD45B	100	71.212	ENSMAMG00000002554	-	100	59.375	Mastacembelus_armatus
ENSG00000099860	GADD45B	98	69.231	ENSMAMG00000000641	-	100	56.875	Mastacembelus_armatus
ENSG00000099860	GADD45B	100	62.121	ENSMAMG00000005463	gadd45aa	98	55.000	Mastacembelus_armatus
ENSG00000099860	GADD45B	100	84.848	ENSMAMG00000016179	gadd45bb	99	69.811	Mastacembelus_armatus
ENSG00000099860	GADD45B	100	74.242	ENSMZEG00005007026	gadd45ga	100	57.055	Maylandia_zebra
ENSG00000099860	GADD45B	100	51.515	ENSMZEG00005010391	gadd45ab	78	48.125	Maylandia_zebra
ENSG00000099860	GADD45B	98	69.231	ENSMZEG00005014453	-	100	56.250	Maylandia_zebra
ENSG00000099860	GADD45B	100	60.606	ENSMZEG00005003065	-	98	51.592	Maylandia_zebra
ENSG00000099860	GADD45B	100	83.333	ENSMZEG00005003049	gadd45bb	100	68.125	Maylandia_zebra
ENSG00000099860	GADD45B	100	72.727	ENSMZEG00005000203	-	92	62.329	Maylandia_zebra
ENSG00000099860	GADD45B	100	65.152	ENSMZEG00005004348	gadd45aa	100	56.849	Maylandia_zebra
ENSG00000099860	GADD45B	91	70.000	ENSMZEG00005014462	-	85	58.993	Maylandia_zebra
ENSG00000099860	GADD45B	91	48.333	ENSMZEG00005003101	-	83	38.298	Maylandia_zebra
ENSG00000099860	GADD45B	83	74.545	ENSMGAG00000011990	GADD45A	99	61.940	Meleagris_gallopavo
ENSG00000099860	GADD45B	100	95.455	ENSMAUG00000015240	Gadd45b	100	92.500	Mesocricetus_auratus
ENSG00000099860	GADD45B	100	66.667	ENSMAUG00000013029	Gadd45a	100	56.970	Mesocricetus_auratus
ENSG00000099860	GADD45B	100	68.182	ENSMAUG00000020102	Gadd45g	100	54.938	Mesocricetus_auratus
ENSG00000099860	GADD45B	100	98.485	ENSMICG00000031371	GADD45B	100	97.500	Microcebus_murinus
ENSG00000099860	GADD45B	100	68.182	ENSMICG00000030733	GADD45G	100	54.878	Microcebus_murinus
ENSG00000099860	GADD45B	100	65.152	ENSMICG00000037822	GADD45A	100	55.758	Microcebus_murinus
ENSG00000099860	GADD45B	100	68.182	ENSMOCG00000017058	Gadd45g	100	54.938	Microtus_ochrogaster
ENSG00000099860	GADD45B	100	66.667	ENSMOCG00000014496	Gadd45a	100	56.364	Microtus_ochrogaster
ENSG00000099860	GADD45B	100	95.455	ENSMOCG00000019277	Gadd45b	100	93.750	Microtus_ochrogaster
ENSG00000099860	GADD45B	100	75.758	ENSMMOG00000001205	gadd45ga	100	57.055	Mola_mola
ENSG00000099860	GADD45B	100	62.121	ENSMMOG00000017036	gadd45ab	98	53.125	Mola_mola
ENSG00000099860	GADD45B	100	62.121	ENSMMOG00000006189	gadd45aa	100	53.750	Mola_mola
ENSG00000099860	GADD45B	100	75.758	ENSMMOG00000007683	gadd45ba	63	53.020	Mola_mola
ENSG00000099860	GADD45B	98	64.615	ENSMMOG00000012032	-	100	54.601	Mola_mola
ENSG00000099860	GADD45B	100	71.212	ENSMMOG00000008700	-	87	58.219	Mola_mola
ENSG00000099860	GADD45B	98	66.154	ENSMMOG00000012135	-	100	56.250	Mola_mola
ENSG00000099860	GADD45B	100	65.152	ENSMODG00000000788	GADD45A	100	55.357	Monodelphis_domestica
ENSG00000099860	GADD45B	100	68.182	ENSMODG00000001225	GADD45G	100	53.086	Monodelphis_domestica
ENSG00000099860	GADD45B	100	93.939	ENSMODG00000004843	GADD45B	100	86.250	Monodelphis_domestica
ENSG00000099860	GADD45B	100	65.152	ENSMALG00000009801	-	100	57.931	Monopterus_albus
ENSG00000099860	GADD45B	100	62.121	ENSMALG00000001312	gadd45aa	98	55.280	Monopterus_albus
ENSG00000099860	GADD45B	98	69.231	ENSMALG00000009789	-	100	57.500	Monopterus_albus
ENSG00000099860	GADD45B	100	63.636	ENSMALG00000014425	gadd45ab	100	55.000	Monopterus_albus
ENSG00000099860	GADD45B	100	81.818	ENSMALG00000020506	gadd45bb	86	67.296	Monopterus_albus
ENSG00000099860	GADD45B	100	75.758	ENSMALG00000017568	gadd45ga	100	57.669	Monopterus_albus
ENSG00000099860	GADD45B	100	71.212	ENSMALG00000010171	-	97	57.962	Monopterus_albus
ENSG00000099860	GADD45B	100	65.152	MGP_CAROLIEiJ_G0028471	Gadd45a	100	56.364	Mus_caroli
ENSG00000099860	GADD45B	100	95.455	MGP_CAROLIEiJ_G0015612	Gadd45b	100	93.125	Mus_caroli
ENSG00000099860	GADD45B	100	68.182	MGP_CAROLIEiJ_G0018521	Gadd45g	100	55.556	Mus_caroli
ENSG00000099860	GADD45B	100	65.152	ENSMUSG00000036390	Gadd45a	100	56.364	Mus_musculus
ENSG00000099860	GADD45B	100	68.182	ENSMUSG00000021453	Gadd45g	100	55.556	Mus_musculus
ENSG00000099860	GADD45B	100	95.455	ENSMUSG00000015312	Gadd45b	100	93.793	Mus_musculus
ENSG00000099860	GADD45B	100	65.152	MGP_PahariEiJ_G0022207	Gadd45a	100	56.364	Mus_pahari
ENSG00000099860	GADD45B	100	68.182	MGP_PahariEiJ_G0019587	Gadd45g	100	55.556	Mus_pahari
ENSG00000099860	GADD45B	100	95.455	MGP_PahariEiJ_G0031025	Gadd45b	100	92.500	Mus_pahari
ENSG00000099860	GADD45B	100	68.182	MGP_SPRETEiJ_G0019402	Gadd45g	100	58.333	Mus_spretus
ENSG00000099860	GADD45B	100	95.455	MGP_SPRETEiJ_G0016430	Gadd45b	100	93.125	Mus_spretus
ENSG00000099860	GADD45B	100	65.152	MGP_SPRETEiJ_G0029476	Gadd45a	99	60.870	Mus_spretus
ENSG00000099860	GADD45B	100	65.152	ENSMPUG00000000798	GADD45A	100	55.758	Mustela_putorius_furo
ENSG00000099860	GADD45B	100	98.125	ENSMPUG00000006641	GADD45B	100	98.125	Mustela_putorius_furo
ENSG00000099860	GADD45B	100	66.667	ENSMPUG00000008466	GADD45G	100	54.938	Mustela_putorius_furo
ENSG00000099860	GADD45B	100	68.182	ENSMLUG00000011563	GADD45G	100	55.556	Myotis_lucifugus
ENSG00000099860	GADD45B	100	65.152	ENSMLUG00000004708	GADD45A	100	55.152	Myotis_lucifugus
ENSG00000099860	GADD45B	100	96.970	ENSMLUG00000009419	GADD45B	100	96.875	Myotis_lucifugus
ENSG00000099860	GADD45B	100	68.182	ENSNGAG00000006719	Gadd45g	100	54.938	Nannospalax_galili
ENSG00000099860	GADD45B	100	66.667	ENSNGAG00000010577	Gadd45a	100	56.364	Nannospalax_galili
ENSG00000099860	GADD45B	100	92.424	ENSNGAG00000021952	Gadd45b	100	90.625	Nannospalax_galili
ENSG00000099860	GADD45B	100	74.242	ENSNBRG00000014444	gadd45ga	100	56.442	Neolamprologus_brichardi
ENSG00000099860	GADD45B	100	60.606	ENSNBRG00000017336	-	95	54.483	Neolamprologus_brichardi
ENSG00000099860	GADD45B	100	66.667	ENSNBRG00000021837	-	95	57.931	Neolamprologus_brichardi
ENSG00000099860	GADD45B	100	65.152	ENSNBRG00000016121	gadd45ab	98	53.750	Neolamprologus_brichardi
ENSG00000099860	GADD45B	98	69.231	ENSNBRG00000021929	-	100	55.625	Neolamprologus_brichardi
ENSG00000099860	GADD45B	100	83.333	ENSNBRG00000017371	gadd45bb	100	68.750	Neolamprologus_brichardi
ENSG00000099860	GADD45B	100	65.152	ENSNBRG00000002246	gadd45aa	100	55.901	Neolamprologus_brichardi
ENSG00000099860	GADD45B	100	72.727	ENSNBRG00000021364	-	89	61.644	Neolamprologus_brichardi
ENSG00000099860	GADD45B	100	68.182	ENSNLEG00000000452	GADD45G	100	55.556	Nomascus_leucogenys
ENSG00000099860	GADD45B	100	65.152	ENSNLEG00000009242	GADD45A	100	55.758	Nomascus_leucogenys
ENSG00000099860	GADD45B	100	93.939	ENSMEUG00000009771	GADD45B	100	87.500	Notamacropus_eugenii
ENSG00000099860	GADD45B	100	68.182	ENSMEUG00000012351	GADD45G	99	53.704	Notamacropus_eugenii
ENSG00000099860	GADD45B	100	65.152	ENSMEUG00000014010	GADD45A	100	58.407	Notamacropus_eugenii
ENSG00000099860	GADD45B	100	65.152	ENSOPRG00000006440	GADD45A	100	55.758	Ochotona_princeps
ENSG00000099860	GADD45B	100	66.667	ENSOPRG00000014056	GADD45G	94	56.061	Ochotona_princeps
ENSG00000099860	GADD45B	100	93.125	ENSOPRG00000006940	GADD45B	100	93.125	Ochotona_princeps
ENSG00000099860	GADD45B	100	98.485	ENSODEG00000014386	GADD45B	100	96.250	Octodon_degus
ENSG00000099860	GADD45B	100	68.182	ENSODEG00000000725	GADD45G	100	56.173	Octodon_degus
ENSG00000099860	GADD45B	100	65.152	ENSODEG00000007377	GADD45A	100	56.173	Octodon_degus
ENSG00000099860	GADD45B	100	66.667	ENSONIG00000012803	-	100	57.931	Oreochromis_niloticus
ENSG00000099860	GADD45B	100	65.152	ENSONIG00000010543	gadd45aa	98	55.280	Oreochromis_niloticus
ENSG00000099860	GADD45B	100	83.333	ENSONIG00000007306	gadd45bb	100	68.750	Oreochromis_niloticus
ENSG00000099860	GADD45B	100	62.121	ENSONIG00000007304	-	84	54.483	Oreochromis_niloticus
ENSG00000099860	GADD45B	98	69.231	ENSONIG00000012799	-	100	56.875	Oreochromis_niloticus
ENSG00000099860	GADD45B	100	65.152	ENSONIG00000019233	gadd45ab	98	53.750	Oreochromis_niloticus
ENSG00000099860	GADD45B	100	72.727	ENSONIG00000001116	-	92	61.644	Oreochromis_niloticus
ENSG00000099860	GADD45B	100	74.242	ENSONIG00000015195	gadd45ga	98	56.024	Oreochromis_niloticus
ENSG00000099860	GADD45B	100	65.152	ENSOANG00000007766	-	50	54.938	Ornithorhynchus_anatinus
ENSG00000099860	GADD45B	100	89.394	ENSOANG00000013858	GADD45B	100	82.500	Ornithorhynchus_anatinus
ENSG00000099860	GADD45B	100	68.182	ENSOCUG00000013296	GADD45G	100	57.639	Oryctolagus_cuniculus
ENSG00000099860	GADD45B	100	65.152	ENSOCUG00000008954	GADD45A	100	55.758	Oryctolagus_cuniculus
ENSG00000099860	GADD45B	100	57.669	ENSORLG00000030080	gadd45ga	73	57.669	Oryzias_latipes
ENSG00000099860	GADD45B	100	84.848	ENSORLG00000025626	gadd45b	100	68.125	Oryzias_latipes
ENSG00000099860	GADD45B	100	62.121	ENSORLG00000005244	gadd45a	98	54.375	Oryzias_latipes
ENSG00000099860	GADD45B	100	63.636	ENSORLG00000022819	-	100	57.241	Oryzias_latipes
ENSG00000099860	GADD45B	98	64.615	ENSORLG00000014766	GADD45G	100	55.625	Oryzias_latipes
ENSG00000099860	GADD45B	100	71.212	ENSORLG00000022536	-	68	58.553	Oryzias_latipes
ENSG00000099860	GADD45B	100	71.212	ENSORLG00020014020	-	100	56.875	Oryzias_latipes_hni
ENSG00000099860	GADD45B	100	63.636	ENSORLG00020022159	gadd45aa	98	55.000	Oryzias_latipes_hni
ENSG00000099860	GADD45B	100	57.669	ENSORLG00020002528	gadd45ga	73	57.669	Oryzias_latipes_hni
ENSG00000099860	GADD45B	100	63.636	ENSORLG00020003179	-	80	57.931	Oryzias_latipes_hni
ENSG00000099860	GADD45B	100	84.848	ENSORLG00020002478	gadd45b	100	68.125	Oryzias_latipes_hni
ENSG00000099860	GADD45B	98	64.615	ENSORLG00020003167	GADD45G	100	55.625	Oryzias_latipes_hni
ENSG00000099860	GADD45B	98	63.077	ENSORLG00015016382	-	100	55.000	Oryzias_latipes_hsok
ENSG00000099860	GADD45B	100	71.212	ENSORLG00015012554	-	68	58.553	Oryzias_latipes_hsok
ENSG00000099860	GADD45B	100	84.848	ENSORLG00015021997	gadd45b	100	68.125	Oryzias_latipes_hsok
ENSG00000099860	GADD45B	100	63.636	ENSORLG00015005773	gadd45aa	52	55.000	Oryzias_latipes_hsok
ENSG00000099860	GADD45B	100	65.152	ENSORLG00015016388	GADD45G	100	58.621	Oryzias_latipes_hsok
ENSG00000099860	GADD45B	100	57.669	ENSORLG00015011140	gadd45ga	73	57.669	Oryzias_latipes_hsok
ENSG00000099860	GADD45B	100	60.606	ENSOMEG00000007023	-	100	55.862	Oryzias_melastigma
ENSG00000099860	GADD45B	100	57.669	ENSOMEG00000021130	gadd45ga	100	57.669	Oryzias_melastigma
ENSG00000099860	GADD45B	100	83.333	ENSOMEG00000015423	gadd45bb	50	67.500	Oryzias_melastigma
ENSG00000099860	GADD45B	100	71.212	ENSOMEG00000011414	-	94	58.784	Oryzias_melastigma
ENSG00000099860	GADD45B	98	64.615	ENSOMEG00000007009	-	100	55.000	Oryzias_melastigma
ENSG00000099860	GADD45B	100	63.636	ENSOMEG00000017064	gadd45aa	77	55.625	Oryzias_melastigma
ENSG00000099860	GADD45B	100	68.182	ENSOGAG00000002142	GADD45G	100	54.938	Otolemur_garnettii
ENSG00000099860	GADD45B	100	65.152	ENSOGAG00000032078	GADD45A	100	55.758	Otolemur_garnettii
ENSG00000099860	GADD45B	100	100.000	ENSOGAG00000000367	GADD45B	100	100.000	Otolemur_garnettii
ENSG00000099860	GADD45B	100	98.485	ENSOARG00000013671	GADD45B	100	98.125	Ovis_aries
ENSG00000099860	GADD45B	100	65.152	ENSOARG00000011356	GADD45A	100	55.152	Ovis_aries
ENSG00000099860	GADD45B	100	68.182	ENSOARG00000007786	GADD45G	100	55.556	Ovis_aries
ENSG00000099860	GADD45B	100	65.152	ENSPPAG00000042185	GADD45A	100	55.758	Pan_paniscus
ENSG00000099860	GADD45B	100	68.182	ENSPPAG00000028549	GADD45G	100	55.556	Pan_paniscus
ENSG00000099860	GADD45B	100	100.000	ENSPPAG00000043714	GADD45B	100	100.000	Pan_paniscus
ENSG00000099860	GADD45B	100	65.152	ENSPPRG00000009546	GADD45A	100	55.758	Panthera_pardus
ENSG00000099860	GADD45B	100	99.375	ENSPPRG00000013871	GADD45B	100	99.375	Panthera_pardus
ENSG00000099860	GADD45B	100	68.182	ENSPPRG00000023729	GADD45G	100	55.556	Panthera_pardus
ENSG00000099860	GADD45B	100	78.125	ENSPTIG00000014382	GADD45B	100	78.125	Panthera_tigris_altaica
ENSG00000099860	GADD45B	100	65.152	ENSPTIG00000002992	GADD45A	100	57.333	Panthera_tigris_altaica
ENSG00000099860	GADD45B	100	68.182	ENSPTRG00000021095	GADD45G	100	55.556	Pan_troglodytes
ENSG00000099860	GADD45B	100	65.152	ENSPTRG00000000842	GADD45A	100	55.758	Pan_troglodytes
ENSG00000099860	GADD45B	100	100.000	ENSPTRG00000044298	GADD45B	100	100.000	Pan_troglodytes
ENSG00000099860	GADD45B	100	68.182	ENSPANG00000024875	GADD45G	100	55.556	Papio_anubis
ENSG00000099860	GADD45B	100	100.000	ENSPANG00000022954	GADD45B	100	99.375	Papio_anubis
ENSG00000099860	GADD45B	100	65.152	ENSPANG00000005666	GADD45A	100	56.364	Papio_anubis
ENSG00000099860	GADD45B	98	64.615	ENSPKIG00000017577	-	100	51.875	Paramormyrops_kingsleyae
ENSG00000099860	GADD45B	98	64.615	ENSPKIG00000017590	-	100	51.875	Paramormyrops_kingsleyae
ENSG00000099860	GADD45B	100	63.636	ENSPKIG00000017605	-	89	52.941	Paramormyrops_kingsleyae
ENSG00000099860	GADD45B	100	83.333	ENSPKIG00000003412	gadd45ba	100	68.944	Paramormyrops_kingsleyae
ENSG00000099860	GADD45B	100	59.091	ENSPKIG00000005239	gadd45aa	98	55.000	Paramormyrops_kingsleyae
ENSG00000099860	GADD45B	100	72.727	ENSPKIG00000017614	gadd45ga	100	57.055	Paramormyrops_kingsleyae
ENSG00000099860	GADD45B	74	73.469	ENSPSIG00000005978	GADD45A	86	60.305	Pelodiscus_sinensis
ENSG00000099860	GADD45B	100	71.875	ENSPSIG00000012258	GADD45B	100	71.875	Pelodiscus_sinensis
ENSG00000099860	GADD45B	100	69.697	ENSPSIG00000013922	GADD45G	100	56.790	Pelodiscus_sinensis
ENSG00000099860	GADD45B	100	62.121	ENSPMGG00000002153	gadd45aa	100	53.049	Periophthalmus_magnuspinnatus
ENSG00000099860	GADD45B	100	77.273	ENSPMGG00000004238	gadd45bb	100	64.375	Periophthalmus_magnuspinnatus
ENSG00000099860	GADD45B	100	53.988	ENSPMGG00000022218	gadd45ga	100	53.988	Periophthalmus_magnuspinnatus
ENSG00000099860	GADD45B	69	52.252	ENSPMGG00000002782	-	93	52.252	Periophthalmus_magnuspinnatus
ENSG00000099860	GADD45B	98	68.657	ENSPMGG00000000923	-	97	57.718	Periophthalmus_magnuspinnatus
ENSG00000099860	GADD45B	100	65.152	ENSPMGG00000021717	gadd45ab	98	53.125	Periophthalmus_magnuspinnatus
ENSG00000099860	GADD45B	53	71.429	ENSPMGG00000022908	-	98	52.252	Periophthalmus_magnuspinnatus
ENSG00000099860	GADD45B	91	61.667	ENSPMGG00000022905	-	100	49.068	Periophthalmus_magnuspinnatus
ENSG00000099860	GADD45B	100	68.182	ENSPEMG00000020132	Gadd45g	100	54.938	Peromyscus_maniculatus_bairdii
ENSG00000099860	GADD45B	100	66.667	ENSPEMG00000022414	Gadd45a	100	56.970	Peromyscus_maniculatus_bairdii
ENSG00000099860	GADD45B	100	95.455	ENSPEMG00000021504	Gadd45b	100	93.125	Peromyscus_maniculatus_bairdii
ENSG00000099860	GADD45B	100	68.182	ENSPCIG00000024947	GADD45G	100	56.944	Phascolarctos_cinereus
ENSG00000099860	GADD45B	100	93.939	ENSPCIG00000009367	GADD45B	100	86.875	Phascolarctos_cinereus
ENSG00000099860	GADD45B	100	65.152	ENSPCIG00000028889	GADD45A	100	54.386	Phascolarctos_cinereus
ENSG00000099860	GADD45B	100	63.636	ENSPFOG00000002733	-	100	55.782	Poecilia_formosa
ENSG00000099860	GADD45B	100	65.152	ENSPFOG00000016368	gadd45ab	98	53.125	Poecilia_formosa
ENSG00000099860	GADD45B	98	64.615	ENSPFOG00000002787	-	99	54.375	Poecilia_formosa
ENSG00000099860	GADD45B	100	74.242	ENSPFOG00000008266	gadd45ga	99	58.282	Poecilia_formosa
ENSG00000099860	GADD45B	100	71.212	ENSPFOG00000014239	-	92	61.644	Poecilia_formosa
ENSG00000099860	GADD45B	100	62.121	ENSPFOG00000017519	gadd45aa	98	54.375	Poecilia_formosa
ENSG00000099860	GADD45B	100	87.879	ENSPFOG00000003529	gadd45bb	92	70.440	Poecilia_formosa
ENSG00000099860	GADD45B	100	87.879	ENSPLAG00000009592	gadd45bb	99	71.528	Poecilia_latipinna
ENSG00000099860	GADD45B	98	64.615	ENSPLAG00000019164	-	100	54.375	Poecilia_latipinna
ENSG00000099860	GADD45B	100	74.242	ENSPLAG00000016153	gadd45ga	100	57.669	Poecilia_latipinna
ENSG00000099860	GADD45B	100	71.212	ENSPLAG00000008005	-	92	61.644	Poecilia_latipinna
ENSG00000099860	GADD45B	94	64.516	ENSPLAG00000019196	-	88	58.209	Poecilia_latipinna
ENSG00000099860	GADD45B	100	62.121	ENSPLAG00000000096	gadd45aa	98	54.375	Poecilia_latipinna
ENSG00000099860	GADD45B	100	65.152	ENSPLAG00000018037	gadd45ab	100	53.125	Poecilia_latipinna
ENSG00000099860	GADD45B	100	71.212	ENSPMEG00000000043	-	92	61.644	Poecilia_mexicana
ENSG00000099860	GADD45B	94	66.129	ENSPMEG00000015435	-	91	56.738	Poecilia_mexicana
ENSG00000099860	GADD45B	98	64.615	ENSPMEG00000015391	-	100	54.375	Poecilia_mexicana
ENSG00000099860	GADD45B	100	65.152	ENSPMEG00000013880	gadd45ab	100	53.125	Poecilia_mexicana
ENSG00000099860	GADD45B	100	87.879	ENSPMEG00000004060	gadd45bb	99	70.440	Poecilia_mexicana
ENSG00000099860	GADD45B	100	62.121	ENSPMEG00000010865	gadd45aa	98	54.375	Poecilia_mexicana
ENSG00000099860	GADD45B	100	74.242	ENSPMEG00000002205	gadd45ga	100	58.282	Poecilia_mexicana
ENSG00000099860	GADD45B	98	66.154	ENSPREG00000001461	gadd45gb.1	92	52.555	Poecilia_reticulata
ENSG00000099860	GADD45B	100	62.121	ENSPREG00000008238	gadd45aa	98	54.375	Poecilia_reticulata
ENSG00000099860	GADD45B	100	71.212	ENSPREG00000010735	-	92	61.644	Poecilia_reticulata
ENSG00000099860	GADD45B	100	65.152	ENSPREG00000013887	gadd45ab	63	53.125	Poecilia_reticulata
ENSG00000099860	GADD45B	100	74.242	ENSPREG00000016178	gadd45ga	100	58.282	Poecilia_reticulata
ENSG00000099860	GADD45B	100	87.879	ENSPREG00000000843	gadd45bb	99	69.182	Poecilia_reticulata
ENSG00000099860	GADD45B	100	68.182	ENSPPYG00000019362	GADD45G	100	55.556	Pongo_abelii
ENSG00000099860	GADD45B	100	65.152	ENSPPYG00000001254	GADD45A	100	55.758	Pongo_abelii
ENSG00000099860	GADD45B	100	100.000	ENSPPYG00000009354	-	89	99.237	Pongo_abelii
ENSG00000099860	GADD45B	100	52.121	ENSPCAG00000014091	GADD45A	100	52.121	Procavia_capensis
ENSG00000099860	GADD45B	100	64.179	ENSPCAG00000016888	GADD45G	100	53.988	Procavia_capensis
ENSG00000099860	GADD45B	100	100.000	ENSPCAG00000006553	GADD45B	100	96.748	Procavia_capensis
ENSG00000099860	GADD45B	100	100.000	ENSPCOG00000013278	GADD45B	100	98.125	Propithecus_coquereli
ENSG00000099860	GADD45B	100	68.182	ENSPCOG00000021885	GADD45G	100	54.321	Propithecus_coquereli
ENSG00000099860	GADD45B	100	65.152	ENSPCOG00000023251	GADD45A	100	55.758	Propithecus_coquereli
ENSG00000099860	GADD45B	100	65.152	ENSPVAG00000013527	GADD45A	100	55.758	Pteropus_vampyrus
ENSG00000099860	GADD45B	100	68.182	ENSPVAG00000015037	GADD45G	100	54.938	Pteropus_vampyrus
ENSG00000099860	GADD45B	100	96.970	ENSPVAG00000014560	GADD45B	100	95.625	Pteropus_vampyrus
ENSG00000099860	GADD45B	100	74.242	ENSPNYG00000015744	gadd45ga	100	57.055	Pundamilia_nyererei
ENSG00000099860	GADD45B	100	72.727	ENSPNYG00000013073	-	92	62.329	Pundamilia_nyererei
ENSG00000099860	GADD45B	100	83.333	ENSPNYG00000000960	gadd45bb	100	68.750	Pundamilia_nyererei
ENSG00000099860	GADD45B	98	69.231	ENSPNYG00000016524	-	100	56.250	Pundamilia_nyererei
ENSG00000099860	GADD45B	100	65.152	ENSPNYG00000002467	gadd45aa	98	55.901	Pundamilia_nyererei
ENSG00000099860	GADD45B	100	59.091	ENSPNYG00000001014	-	98	50.955	Pundamilia_nyererei
ENSG00000099860	GADD45B	100	65.152	ENSPNYG00000021665	gadd45ab	100	53.750	Pundamilia_nyererei
ENSG00000099860	GADD45B	91	70.000	ENSPNYG00000016538	-	85	58.993	Pundamilia_nyererei
ENSG00000099860	GADD45B	100	65.152	ENSPNAG00000027296	gadd45aa	100	56.250	Pygocentrus_nattereri
ENSG00000099860	GADD45B	100	60.606	ENSPNAG00000015407	-	100	54.483	Pygocentrus_nattereri
ENSG00000099860	GADD45B	100	63.636	ENSPNAG00000001129	gadd45ab	98	54.375	Pygocentrus_nattereri
ENSG00000099860	GADD45B	100	86.364	ENSPNAG00000023900	gadd45ba	100	70.625	Pygocentrus_nattereri
ENSG00000099860	GADD45B	100	69.697	ENSPNAG00000023902	gadd45ga	100	56.442	Pygocentrus_nattereri
ENSG00000099860	GADD45B	100	72.727	ENSPNAG00000003011	-	100	59.375	Pygocentrus_nattereri
ENSG00000099860	GADD45B	91	70.000	ENSPNAG00000015424	-	100	55.625	Pygocentrus_nattereri
ENSG00000099860	GADD45B	100	65.152	ENSRNOG00000005615	Gadd45a	100	56.364	Rattus_norvegicus
ENSG00000099860	GADD45B	100	95.455	ENSRNOG00000019822	Gadd45b	100	92.500	Rattus_norvegicus
ENSG00000099860	GADD45B	100	68.182	ENSRNOG00000013090	Gadd45g	100	55.556	Rattus_norvegicus
ENSG00000099860	GADD45B	100	65.152	ENSRBIG00000042903	GADD45A	100	55.758	Rhinopithecus_bieti
ENSG00000099860	GADD45B	100	100.000	ENSRBIG00000035225	GADD45B	100	99.375	Rhinopithecus_bieti
ENSG00000099860	GADD45B	100	68.182	ENSRBIG00000036234	GADD45G	100	55.556	Rhinopithecus_bieti
ENSG00000099860	GADD45B	100	65.152	ENSRROG00000032533	GADD45A	100	55.758	Rhinopithecus_roxellana
ENSG00000099860	GADD45B	100	100.000	ENSRROG00000041780	GADD45B	100	99.375	Rhinopithecus_roxellana
ENSG00000099860	GADD45B	100	68.182	ENSRROG00000039055	GADD45G	100	58.333	Rhinopithecus_roxellana
ENSG00000099860	GADD45B	100	68.182	ENSSBOG00000026492	GADD45G	100	55.556	Saimiri_boliviensis_boliviensis
ENSG00000099860	GADD45B	100	65.152	ENSSBOG00000026960	GADD45A	100	55.758	Saimiri_boliviensis_boliviensis
ENSG00000099860	GADD45B	100	98.750	ENSSBOG00000026150	GADD45B	100	98.750	Saimiri_boliviensis_boliviensis
ENSG00000099860	GADD45B	100	68.182	ENSSHAG00000004260	GADD45G	100	54.321	Sarcophilus_harrisii
ENSG00000099860	GADD45B	100	93.939	ENSSHAG00000008384	GADD45B	100	86.875	Sarcophilus_harrisii
ENSG00000099860	GADD45B	100	78.788	ENSSFOG00015021979	-	96	59.119	Scleropages_formosus
ENSG00000099860	GADD45B	100	63.636	ENSSFOG00015011449	gadd45a	100	57.500	Scleropages_formosus
ENSG00000099860	GADD45B	89	72.881	ENSSFOG00015006839	GADD45G	100	52.500	Scleropages_formosus
ENSG00000099860	GADD45B	100	75.758	ENSSFOG00015006860	gadd45ga	100	59.509	Scleropages_formosus
ENSG00000099860	GADD45B	100	66.667	ENSSFOG00015006812	GADD45G	85	53.797	Scleropages_formosus
ENSG00000099860	GADD45B	100	83.333	ENSSFOG00015017631	gadd45bb	100	70.625	Scleropages_formosus
ENSG00000099860	GADD45B	100	84.848	ENSSFOG00015021958	gadd45b	100	70.807	Scleropages_formosus
ENSG00000099860	GADD45B	100	83.333	ENSSMAG00000017069	gadd45bb	100	68.323	Scophthalmus_maximus
ENSG00000099860	GADD45B	100	62.121	ENSSMAG00000006526	gadd45aa	98	53.012	Scophthalmus_maximus
ENSG00000099860	GADD45B	100	71.212	ENSSMAG00000014704	-	95	60.265	Scophthalmus_maximus
ENSG00000099860	GADD45B	100	74.242	ENSSMAG00000002971	gadd45ga	71	57.669	Scophthalmus_maximus
ENSG00000099860	GADD45B	100	59.091	ENSSMAG00000003286	gadd45ab	100	53.125	Scophthalmus_maximus
ENSG00000099860	GADD45B	98	70.769	ENSSDUG00000002354	-	100	58.125	Seriola_dumerili
ENSG00000099860	GADD45B	100	62.121	ENSSDUG00000012043	gadd45aa	98	54.658	Seriola_dumerili
ENSG00000099860	GADD45B	100	63.636	ENSSDUG00000022494	gadd45ab	100	55.000	Seriola_dumerili
ENSG00000099860	GADD45B	100	84.848	ENSSDUG00000020891	gadd45bb	100	68.750	Seriola_dumerili
ENSG00000099860	GADD45B	100	68.182	ENSSDUG00000002371	-	100	55.828	Seriola_dumerili
ENSG00000099860	GADD45B	100	75.758	ENSSDUG00000002744	gadd45ga	100	59.509	Seriola_dumerili
ENSG00000099860	GADD45B	100	68.182	ENSSDUG00000012698	-	92	60.274	Seriola_dumerili
ENSG00000099860	GADD45B	98	72.308	ENSSLDG00000016220	-	100	58.750	Seriola_lalandi_dorsalis
ENSG00000099860	GADD45B	100	75.758	ENSSLDG00000019027	gadd45ga	100	59.509	Seriola_lalandi_dorsalis
ENSG00000099860	GADD45B	100	62.121	ENSSLDG00000016856	gadd45aa	98	54.658	Seriola_lalandi_dorsalis
ENSG00000099860	GADD45B	91	70.000	ENSSLDG00000016268	-	83	55.147	Seriola_lalandi_dorsalis
ENSG00000099860	GADD45B	97	68.750	ENSSLDG00000022607	-	96	60.839	Seriola_lalandi_dorsalis
ENSG00000099860	GADD45B	100	63.636	ENSSLDG00000019947	gadd45ab	76	55.000	Seriola_lalandi_dorsalis
ENSG00000099860	GADD45B	100	84.848	ENSSLDG00000013918	gadd45bb	100	68.750	Seriola_lalandi_dorsalis
ENSG00000099860	GADD45B	69	56.897	ENSSARG00000014580	GADD45A	70	56.897	Sorex_araneus
ENSG00000099860	GADD45B	100	69.697	ENSSPUG00000009715	GADD45G	84	58.784	Sphenodon_punctatus
ENSG00000099860	GADD45B	100	83.333	ENSSPUG00000006949	GADD45B	100	79.310	Sphenodon_punctatus
ENSG00000099860	GADD45B	100	65.152	ENSSPUG00000015111	GADD45A	100	58.621	Sphenodon_punctatus
ENSG00000099860	GADD45B	100	83.333	ENSSPAG00000019883	gadd45bb	100	68.750	Stegastes_partitus
ENSG00000099860	GADD45B	100	72.727	ENSSPAG00000018093	-	91	58.667	Stegastes_partitus
ENSG00000099860	GADD45B	100	63.636	ENSSPAG00000008793	gadd45ab	100	54.375	Stegastes_partitus
ENSG00000099860	GADD45B	100	62.121	ENSSPAG00000000582	gadd45aa	98	52.439	Stegastes_partitus
ENSG00000099860	GADD45B	100	75.758	ENSSPAG00000006377	gadd45ga	100	57.669	Stegastes_partitus
ENSG00000099860	GADD45B	91	70.000	ENSSPAG00000005713	-	90	59.712	Stegastes_partitus
ENSG00000099860	GADD45B	100	65.152	ENSSSCG00000037066	GADD45A	100	54.545	Sus_scrofa
ENSG00000099860	GADD45B	100	98.485	ENSSSCG00000022689	GADD45B	100	98.125	Sus_scrofa
ENSG00000099860	GADD45B	100	68.182	ENSSSCG00000035249	GADD45G	100	56.790	Sus_scrofa
ENSG00000099860	GADD45B	76	74.000	ENSTGUG00000000433	GADD45G	100	65.217	Taeniopygia_guttata
ENSG00000099860	GADD45B	100	66.667	ENSTRUG00000012938	-	100	53.750	Takifugu_rubripes
ENSG00000099860	GADD45B	50	78.788	ENSTRUG00000012876	-	98	55.856	Takifugu_rubripes
ENSG00000099860	GADD45B	100	80.303	ENSTRUG00000010851	gadd45ba	100	65.000	Takifugu_rubripes
ENSG00000099860	GADD45B	100	62.121	ENSTRUG00000021774	gadd45aa	98	55.000	Takifugu_rubripes
ENSG00000099860	GADD45B	100	66.667	ENSTRUG00000020226	-	92	59.589	Takifugu_rubripes
ENSG00000099860	GADD45B	100	72.727	ENSTRUG00000024662	gadd45ga	100	57.669	Takifugu_rubripes
ENSG00000099860	GADD45B	98	63.077	ENSTNIG00000003192	gadd45gb.1	100	52.500	Tetraodon_nigroviridis
ENSG00000099860	GADD45B	100	62.121	ENSTNIG00000006973	gadd45aa	100	55.625	Tetraodon_nigroviridis
ENSG00000099860	GADD45B	100	68.182	ENSTNIG00000017186	-	91	59.589	Tetraodon_nigroviridis
ENSG00000099860	GADD45B	100	72.727	ENSTNIG00000016668	gadd45ga	100	55.215	Tetraodon_nigroviridis
ENSG00000099860	GADD45B	95	76.190	ENSTNIG00000003213	gadd45bb	100	58.750	Tetraodon_nigroviridis
ENSG00000099860	GADD45B	100	65.152	ENSTBEG00000003869	GADD45A	100	55.758	Tupaia_belangeri
ENSG00000099860	GADD45B	100	69.697	ENSTBEG00000001835	GADD45G	100	57.317	Tupaia_belangeri
ENSG00000099860	GADD45B	100	98.485	ENSTTRG00000007080	GADD45B	100	97.500	Tursiops_truncatus
ENSG00000099860	GADD45B	100	65.152	ENSTTRG00000015059	GADD45A	100	55.152	Tursiops_truncatus
ENSG00000099860	GADD45B	100	65.152	ENSUAMG00000027260	GADD45A	100	57.333	Ursus_americanus
ENSG00000099860	GADD45B	100	98.485	ENSUAMG00000013221	GADD45B	100	97.931	Ursus_americanus
ENSG00000099860	GADD45B	100	66.667	ENSUAMG00000016320	GADD45G	95	54.930	Ursus_americanus
ENSG00000099860	GADD45B	61	54.369	ENSUMAG00000006834	GADD45A	100	54.369	Ursus_maritimus
ENSG00000099860	GADD45B	100	98.485	ENSUMAG00000006840	GADD45B	100	98.125	Ursus_maritimus
ENSG00000099860	GADD45B	100	63.636	ENSVVUG00000008309	GADD45A	99	56.000	Vulpes_vulpes
ENSG00000099860	GADD45B	100	98.485	ENSVVUG00000002785	GADD45B	100	98.125	Vulpes_vulpes
ENSG00000099860	GADD45B	100	63.636	ENSXETG00000012392	gadd45a	98	56.250	Xenopus_tropicalis
ENSG00000099860	GADD45B	100	75.758	ENSXETG00000003717	gadd45b	100	61.875	Xenopus_tropicalis
ENSG00000099860	GADD45B	100	72.727	ENSXETG00000026537	gadd45g	100	56.790	Xenopus_tropicalis
ENSG00000099860	GADD45B	98	66.154	ENSXCOG00000006693	-	84	56.818	Xiphophorus_couchianus
ENSG00000099860	GADD45B	100	62.121	ENSXCOG00000007270	gadd45aa	100	54.375	Xiphophorus_couchianus
ENSG00000099860	GADD45B	100	62.121	ENSXCOG00000006708	-	77	53.279	Xiphophorus_couchianus
ENSG00000099860	GADD45B	100	71.212	ENSXCOG00000014180	-	81	56.522	Xiphophorus_couchianus
ENSG00000099860	GADD45B	100	87.879	ENSXCOG00000007175	gadd45bb	99	69.182	Xiphophorus_couchianus
ENSG00000099860	GADD45B	100	65.152	ENSXCOG00000004256	gadd45ab	98	53.125	Xiphophorus_couchianus
ENSG00000099860	GADD45B	100	74.242	ENSXCOG00000006660	gadd45ga	100	58.750	Xiphophorus_couchianus
ENSG00000099860	GADD45B	100	63.636	ENSXMAG00000016542	-	93	55.479	Xiphophorus_maculatus
ENSG00000099860	GADD45B	100	71.212	ENSXMAG00000028113	-	95	60.667	Xiphophorus_maculatus
ENSG00000099860	GADD45B	100	74.242	ENSXMAG00000015952	gadd45ga	100	58.282	Xiphophorus_maculatus
ENSG00000099860	GADD45B	98	66.154	ENSXMAG00000025959	-	100	55.000	Xiphophorus_maculatus
ENSG00000099860	GADD45B	100	65.152	ENSXMAG00000003091	gadd45ab	72	53.125	Xiphophorus_maculatus
ENSG00000099860	GADD45B	100	87.879	ENSXMAG00000013033	gadd45bb	99	69.182	Xiphophorus_maculatus
ENSG00000099860	GADD45B	100	62.121	ENSXMAG00000022990	gadd45aa	98	54.375	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000185	activation of MAPKKK activity	21873635.	IBA	Process
GO:0000185	activation of MAPKKK activity	9827804.	IDA	Process
GO:0000186	activation of MAPKK activity	-	IEA	Process
GO:0005515	protein binding	12052864.16256071.25314077.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	9827804.	IDA	Component
GO:0005737	cytoplasm	21873635.	IBA	Component
GO:0005737	cytoplasm	9827804.	IDA	Component
GO:0006469	negative regulation of protein kinase activity	-	IEA	Process
GO:0006915	apoptotic process	-	IEA	Process
GO:0007275	multicellular organism development	-	IEA	Process
GO:0030154	cell differentiation	-	IEA	Process
GO:0043065	positive regulation of apoptotic process	9827804.	IDA	Process
GO:0046330	positive regulation of JNK cascade	9827804.	IDA	Process
GO:0051726	regulation of cell cycle	21873635.	IBA	Process
GO:1900745	positive regulation of p38MAPK cascade	9827804.	IDA	Process

Cancer associated literatures

PID	Title	Article	Time	Author	Doi
29356020	Matrine inhibits the progression of prostate cancer by promoting expression of GADD45B.	Prostate	2018 Apr	Huang H	doi: 10.1002/pros.23469
24104471	Gadd45 in modulation of solid tumors and leukemia.	Adv Exp Med Biol	2013	Hoffman B	doi: 10.1007/978-1-4614-8289-5_2.
21810943	Identification of growth arrest and DNA-damage-inducible gene beta (GADD45beta) as a novel tumor suppressor in pituitary gonadotrope tumors.	Endocrinology	2011 Oct	Michaelis KA	doi: 10.1210/en.2011-0109
28870783	19p13.3-GADD45B common variants and 19q13.3-PPP1R13L and 19q13.3-CD3EAP in lung cancer risk among Chinese.	Chem Biol Interact	2017 Nov 1	Hou W	doi: 10.1016/j.cbi.2017.08.018
26993769	Genetic variants of GADD45A, GADD45B and MAPK14 predict platinum-based chemotherapy-induced toxicities in Chinese patients with non-small cell lung cancer.	Oncotarget	2016 May 3	Jia M	doi: 10.18632/oncotarget.8052.
29279355	GADD45β Loss Ablates Innate Immunosuppression in Cancer.	Cancer Res	2018 Mar 1	Verzella D	doi: 10.1158/0008-5472.CAN-17-1833

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
BLCA	chr19	2476429	Intron	novel		0.53
BRCA	chr19	2476298	5'UTR	novel		0.21
CESC	chr19	2477541	Silent	novel	Y141Y	0.13
CESC	chr19	2476135	5'UTR	novel		0.33
CESC	chr19	2476587	Missense_Mutation	NA	R35C	0.34	Ribosomal_L7Ae
CESC	chr19	2477089	Silent	NA	I69I	0.11
DLBC	chr19	2476604	Silent	rs544016078	V40V	0.17
GBM	chr19	2477593	Missense_Mutation	NA	E159Q	0.11
GBM	chr19	2476505	Intron	novel		0.22
HNSC	chr19	2477212	Silent	novel	G110G	0.19
HNSC	chr19	2476209	5'UTR	novel		0.26
HNSC	chr19	2476210	5'UTR	novel		0.25
KIRC	chr19	2477621	3'UTR	novel		0.22
KIRC	chr19	2476513	Intron	novel		0.25
KIRC	chr19	2477620	3'UTR	novel		0.33
KIRP	chr19	2477523	Missense_Mutation	novel	L135F	0.5
KIRP	chr19	2477584	Missense_Mutation	NA	S156T	0.31
LGG	chr19	2476507	Intron	novel		0.29
LIHC	chr19	2476229	5'UTR	novel		0.14
LUAD	chr19	2477069	Missense_Mutation	novel	E63K	0.13
LUSC	chr19	2476150	5'UTR	rs536955297		0.41
LUSC	chr19	2477494	Missense_Mutation	NA	H126Y	0.43
SKCM	chr19	2477117	Nonsense_Mutation	NA	Q79*	0.22
SKCM	chr19	2476341	5'UTR	novel		0.2
STAD	chr19	2476308	5'UTR	novel		0.11
STAD	chr19	2476176	5'UTR	novel		0.27
STAD	chr19	2477071	Missense_Mutation	NA	E63D	0.29
THCA	chr19	2476181	5'UTR	novel		0.47
UCEC	chr19	2477499	Silent	rs751565252	T127T	0.2
UCEC	chr19	2477179	Silent	novel	A99A	0.3

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
KIRP	DEL	0.0521	0.058467
LIHC	DEL	0.1865	4.7028e-08
PAAD	DEL	0.1467	0.0060878
READ	DEL	0.1333	0.23023
STAD	DEL	0.2721	1.5798e-05
THCA	DEL	0.014	0.10598
UCS	DEL	0.7679	8.0449e-14

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.0073	Kaplan-Meier Survival Analysis
STAD	0.0057	Kaplan-Meier Survival Analysis
SARC	0.009	Kaplan-Meier Survival Analysis
SKCM	0.0008	Kaplan-Meier Survival Analysis
LUSC	0.0058	Kaplan-Meier Survival Analysis
ESCA	0.016	Kaplan-Meier Survival Analysis
COAD	0.011	Kaplan-Meier Survival Analysis
BLCA	0.047	Kaplan-Meier Survival Analysis
READ	0.012	Kaplan-Meier Survival Analysis
KICH	0.015	Kaplan-Meier Survival Analysis
UCEC	0.04	Kaplan-Meier Survival Analysis
GBM	0.0072	Kaplan-Meier Survival Analysis
LIHC	0.0016	Kaplan-Meier Survival Analysis
LGG	0.0071	Kaplan-Meier Survival Analysis
THCA	0.024	Kaplan-Meier Survival Analysis
UVM	0.033	Kaplan-Meier Survival Analysis
OV	0.0097	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

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Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742