EuRBPDB

Description

RBDs

Literatures

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000100461 (Gene tree)
Gene ID: 55147
Gene Symbol: RBM23
Alias: FLJ10482|CAPERbeta|RNPC4
Full Name: RNA binding motif protein 23
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Minus strand
Length: 25,982 bases
Position: chr14:22,893,206-22,919,187
Accession: 20155
RBP type: canonical RBP
Summary: This gene encodes a member of the U2AF-like family of RNA binding proteins. This protein interacts with some steroid nuclear receptors, localizes to the promoter of a steroid- responsive gene, and increases transcription of steroid-responsive transcriptional reporters in a hormone-dependent manner. It is also implicated in the steroid receptor-dependent regulation of alternative splicing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000339220	RRM_1	PF00076.22	1.1e-34	1	2
ENSP00000339220	RRM_1	PF00076.22	1.1e-34	2	2
ENSP00000382806	RRM_1	PF00076.22	1.2e-34	1	2
ENSP00000382806	RRM_1	PF00076.22	1.2e-34	2	2
ENSP00000438504	RRM_1	PF00076.22	1.3e-34	1	2
ENSP00000438504	RRM_1	PF00076.22	1.3e-34	2	2
ENSP00000352956	RRM_1	PF00076.22	1.4e-34	1	2
ENSP00000352956	RRM_1	PF00076.22	1.4e-34	2	2
ENSP00000452602	RRM_1	PF00076.22	4.9e-23	1	1
ENSP00000451642	RRM_1	PF00076.22	6.6e-23	1	1
ENSP00000452171	RRM_1	PF00076.22	9.2e-14	1	1
ENSP00000450556	RRM_1	PF00076.22	2.5e-09	1	1

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
9678487	Physical association between the EBV protein EBNA-1 and P32/TAP/hyaluronectin.	J Biomed Sci	1998	Chen MR	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000557127	RBM23-226	472	-	-	- (aa)	-	-
ENST00000542016	RBM23-205	1743	XM_011536902	ENSP00000438504	269 (aa)	XP_011535204	G3XAP0
ENST00000399922	RBM23-204	2430	XM_011536892	ENSP00000382806	423 (aa)	XP_011535194	Q86U06
ENST00000554955	RBM23-214	690	-	-	- (aa)	-	-
ENST00000557464	RBM23-230	457	-	ENSP00000451403	66 (aa)	-	G3V3S8
ENST00000557245	RBM23-228	387	-	ENSP00000451838	82 (aa)	-	H0YJN4
ENST00000557571	RBM23-232	573	-	ENSP00000452382	91 (aa)	-	G3V5J5
ENST00000557227	RBM23-227	552	-	ENSP00000450423	21 (aa)	-	G3V225
ENST00000556838	RBM23-223	590	-	-	- (aa)	-	-
ENST00000557403	RBM23-229	826	-	ENSP00000452171	114 (aa)	-	G3V546
ENST00000555722	RBM23-219	602	-	ENSP00000450556	50 (aa)	-	G3V2B4
ENST00000556862	RBM23-224	569	-	ENSP00000452557	92 (aa)	-	G3V5W6
ENST00000554256	RBM23-212	581	-	ENSP00000452583	144 (aa)	-	G3V5Y2
ENST00000307814	RBM23-201	2320	-	-	- (aa)	-	-
ENST00000359890	RBM23-203	10040	XM_011536894	ENSP00000352956	439 (aa)	XP_011535196	Q86U06
ENST00000556186	RBM23-220	603	-	-	- (aa)	-	-
ENST00000553876	RBM23-208	267	-	ENSP00000450672	59 (aa)	-	G3V2H9
ENST00000556365	RBM23-221	549	-	-	- (aa)	-	-
ENST00000346528	RBM23-202	2361	XM_011536895	ENSP00000339220	405 (aa)	XP_011535197	Q86U06
ENST00000553902	RBM23-210	581	-	-	- (aa)	-	-
ENST00000553920	RBM23-211	556	-	-	- (aa)	-	-
ENST00000554618	RBM23-213	588	-	ENSP00000451448	75 (aa)	-	G3V3V3
ENST00000557667	RBM23-233	4240	-	-	- (aa)	-	-
ENST00000553884	RBM23-209	808	-	ENSP00000451642	214 (aa)	-	H0YJJ3
ENST00000557549	RBM23-231	582	-	ENSP00000450558	101 (aa)	-	G3V2B6
ENST00000555209	RBM23-215	2278	-	ENSP00000452602	189 (aa)	-	G3V5Z6
ENST00000553738	RBM23-206	619	-	-	- (aa)	-	-
ENST00000555714	RBM23-218	561	-	-	- (aa)	-	-
ENST00000555676	RBM23-216	583	-	ENSP00000451364	100 (aa)	-	A0A0B4J267
ENST00000555691	RBM23-217	571	-	ENSP00000452538	57 (aa)	-	G3V5V1
ENST00000553777	RBM23-207	328	-	-	- (aa)	-	-
ENST00000556687	RBM23-222	1124	-	-	- (aa)	-	-
ENST00000556984	RBM23-225	575	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000100461's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000100461	Education	9E-13	27225129

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000100461	rs8005677	14	22907469	?	Cognitive ability (MTAG)	29186694	z score decrease	5.747	EFO_0004337\|EFO_0004784
ENSG00000100461	rs34344888	14	22918376	A	Educational attainment (years of education)	27225129	NR unit decrease	0.016260339	EFO_0004784
ENSG00000100461	rs1570342	14	22898976	?	Cortical amyloid beta load	29860282	[NR] unit increase	0.1	EFO_0007707
ENSG00000100461	rs10137343	14	22913431	A	Self-reported math ability	30038396	[0.008-0.0158] unit decrease	0.0119	EFO_0004875
ENSG00000100461	rs10137343	14	22913431	A	Highest math class taken	30038396	[0.01-0.019] unit decrease	0.0146	EFO_0004875
ENSG00000100461	rs4981446	14	22912204	A	Highest math class taken (MTAG)	30038396	[0.012-0.019] unit decrease	0.0156	EFO_0004875
ENSG00000100461	rs11557895	14	22919022	?	Red cell distribution width	30595370			EFO_0005192

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000100461's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000100461	RBM23	64	43.750	ENSG00000101104	PABPC1L	81	43.750
ENSG00000100461	RBM23	64	36.111	ENSG00000254535	PABPC4L	96	36.111
ENSG00000100461	RBM23	63	36.486	ENSG00000196361	ELAVL3	87	36.486
ENSG00000100461	RBM23	59	35.443	ENSG00000135486	HNRNPA1	65	40.385
ENSG00000100461	RBM23	66	34.694	ENSG00000143368	SF3B4	74	36.232
ENSG00000100461	RBM23	50	44.898	ENSG00000122566	HNRNPA2B1	55	44.898
ENSG00000100461	RBM23	72	40.278	ENSG00000090621	PABPC4	60	40.278
ENSG00000100461	RBM23	63	35.135	ENSG00000107105	ELAVL2	91	35.135
ENSG00000100461	RBM23	58	44.444	ENSG00000186288	PABPC1L2A	80	44.444
ENSG00000100461	RBM23	91	33.766	ENSG00000101489	CELF4	59	36.508
ENSG00000100461	RBM23	61	34.146	ENSG00000066044	ELAVL1	95	34.146
ENSG00000100461	RBM23	63	35.135	ENSG00000162374	ELAVL4	90	35.135
ENSG00000100461	RBM23	62	41.667	ENSG00000070756	PABPC1	84	47.059
ENSG00000100461	RBM23	96	33.333	ENSG00000153944	MSI2	82	36.667
ENSG00000100461	RBM23	57	34.328	ENSG00000138668	HNRNPD	69	34.328
ENSG00000100461	RBM23	58	44.444	ENSG00000184388	PABPC1L2B	80	44.444
ENSG00000100461	RBM23	66	37.500	ENSG00000151846	PABPC3	56	37.500
ENSG00000100461	RBM23	56	30.864	ENSG00000197451	HNRNPAB	57	30.864
ENSG00000100461	RBM23	100	90.476	ENSG00000131051	RBM39	88	80.556
ENSG00000100461	RBM23	57	43.243	ENSG00000179950	PUF60	62	39.394

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000100461	RBM23	100	100.000	ENSAMEG00000007322	RBM23	100	89.556	Ailuropoda_melanoleuca
ENSG00000100461	RBM23	100	100.000	ENSACAG00000001569	RBM23	96	73.742	Anolis_carolinensis
ENSG00000100461	RBM23	100	88.596	ENSANAG00000033790	-	100	72.406	Aotus_nancymaae
ENSG00000100461	RBM23	100	89.412	ENSANAG00000031466	-	99	80.000	Aotus_nancymaae
ENSG00000100461	RBM23	100	100.000	ENSBTAG00000038333	RBM23	100	85.097	Bos_taurus
ENSG00000100461	RBM23	100	100.000	ENSCJAG00000008482	RBM23	100	92.857	Callithrix_jacchus
ENSG00000100461	RBM23	100	100.000	ENSCAFG00000011217	RBM23	100	87.059	Canis_familiaris
ENSG00000100461	RBM23	100	100.000	ENSCAFG00020007711	RBM23	100	90.562	Canis_lupus_dingo
ENSG00000100461	RBM23	100	100.000	ENSCHIG00000025709	RBM23	100	85.529	Capra_hircus
ENSG00000100461	RBM23	100	100.000	ENSTSYG00000014755	RBM23	100	97.026	Carlito_syrichta
ENSG00000100461	RBM23	100	100.000	ENSCCAG00000025114	-	100	95.556	Cebus_capucinus
ENSG00000100461	RBM23	100	84.211	ENSCCAG00000028584	-	100	81.041	Cebus_capucinus
ENSG00000100461	RBM23	100	100.000	ENSCATG00000017832	RBM23	100	95.519	Cercocebus_atys
ENSG00000100461	RBM23	100	100.000	ENSCSAG00000016213	RBM23	100	95.249	Chlorocebus_sabaeus
ENSG00000100461	RBM23	100	96.491	ENSCHOG00000004460	-	51	97.468	Choloepus_hoffmanni
ENSG00000100461	RBM23	100	100.000	ENSCPBG00000026096	RBM23	96	70.071	Chrysemys_picta_bellii
ENSG00000100461	RBM23	100	100.000	ENSCANG00000001893	RBM23	100	94.541	Colobus_angolensis_palliatus
ENSG00000100461	RBM23	100	100.000	ENSDNOG00000032457	RBM23	100	86.937	Dasypus_novemcinctus
ENSG00000100461	RBM23	100	100.000	ENSDORG00000004926	-	100	96.654	Dipodomys_ordii
ENSG00000100461	RBM23	100	86.000	ENSETEG00000017915	-	95	80.000	Echinops_telfairi
ENSG00000100461	RBM23	100	100.000	ENSEASG00005011696	RBM23	95	89.070	Equus_asinus_asinus
ENSG00000100461	RBM23	100	100.000	ENSECAG00000009910	RBM23	100	87.788	Equus_caballus
ENSG00000100461	RBM23	100	100.000	ENSEEUG00000015560	RBM23	100	85.618	Erinaceus_europaeus
ENSG00000100461	RBM23	100	100.000	ENSFCAG00000006632	RBM23	100	90.268	Felis_catus
ENSG00000100461	RBM23	69	70.455	ENSGAGG00000003171	-	85	72.727	Gopherus_agassizii
ENSG00000100461	RBM23	100	100.000	ENSGGOG00000015707	RBM23	100	97.163	Gorilla_gorilla
ENSG00000100461	RBM23	100	95.238	ENSHGLG00100006114	RBM23	99	82.883	Heterocephalus_glaber_male
ENSG00000100461	RBM23	100	100.000	ENSSTOG00000010354	RBM23	100	96.654	Ictidomys_tridecemlineatus
ENSG00000100461	RBM23	100	100.000	ENSLAFG00000018567	RBM23	100	84.687	Loxodonta_africana
ENSG00000100461	RBM23	100	100.000	ENSMFAG00000037595	RBM23	100	95.540	Macaca_fascicularis
ENSG00000100461	RBM23	100	100.000	ENSMMUG00000018381	RBM23	100	94.836	Macaca_mulatta
ENSG00000100461	RBM23	100	100.000	ENSMNEG00000042442	RBM23	100	95.519	Macaca_nemestrina
ENSG00000100461	RBM23	100	100.000	ENSMLEG00000039954	RBM23	100	90.888	Mandrillus_leucophaeus
ENSG00000100461	RBM23	100	100.000	ENSMICG00000006364	RBM23	100	95.167	Microcebus_murinus
ENSG00000100461	RBM23	100	100.000	ENSMODG00000024448	RBM23	100	87.225	Monodelphis_domestica
ENSG00000100461	RBM23	100	100.000	ENSMPUG00000007151	RBM23	100	90.112	Mustela_putorius_furo
ENSG00000100461	RBM23	100	98.000	ENSMLUG00000012923	RBM23	100	84.650	Myotis_lucifugus
ENSG00000100461	RBM23	100	100.000	ENSNLEG00000014792	RBM23	100	94.366	Nomascus_leucogenys
ENSG00000100461	RBM23	97	99.099	ENSMEUG00000014548	-	60	97.080	Notamacropus_eugenii
ENSG00000100461	RBM23	100	95.238	ENSOPRG00000001092	RBM23	100	87.387	Ochotona_princeps
ENSG00000100461	RBM23	100	48.052	ENSOANG00000008908	-	100	52.244	Ornithorhynchus_anatinus
ENSG00000100461	RBM23	100	100.000	ENSOCUG00000002006	RBM23	100	89.910	Oryctolagus_cuniculus
ENSG00000100461	RBM23	100	100.000	ENSOGAG00000014794	RBM23	100	81.778	Otolemur_garnettii
ENSG00000100461	RBM23	100	100.000	ENSOARG00000019398	RBM23	100	84.665	Ovis_aries
ENSG00000100461	RBM23	100	100.000	ENSPPAG00000037922	RBM23	100	98.122	Pan_paniscus
ENSG00000100461	RBM23	100	100.000	ENSPPRG00000023344	RBM23	100	90.024	Panthera_pardus
ENSG00000100461	RBM23	100	100.000	ENSPTIG00000007831	RBM23	100	89.051	Panthera_tigris_altaica
ENSG00000100461	RBM23	100	100.000	ENSPTRG00000006151	RBM23	100	97.653	Pan_troglodytes
ENSG00000100461	RBM23	100	100.000	ENSPANG00000001324	RBM23	100	96.324	Papio_anubis
ENSG00000100461	RBM23	100	100.000	ENSPCIG00000027773	RBM23	100	86.463	Phascolarctos_cinereus
ENSG00000100461	RBM23	100	100.000	ENSPPYG00000005649	RBM23	100	96.454	Pongo_abelii
ENSG00000100461	RBM23	100	80.412	ENSPCAG00000006669	RBM23	100	68.692	Procavia_capensis
ENSG00000100461	RBM23	100	100.000	ENSPCOG00000018564	RBM23	100	97.026	Propithecus_coquereli
ENSG00000100461	RBM23	100	100.000	ENSPVAG00000013785	RBM23	100	87.640	Pteropus_vampyrus
ENSG00000100461	RBM23	100	100.000	ENSRBIG00000039276	RBM23	100	94.366	Rhinopithecus_bieti
ENSG00000100461	RBM23	100	100.000	ENSRROG00000044026	RBM23	100	94.366	Rhinopithecus_roxellana
ENSG00000100461	RBM23	100	78.070	ENSSBOG00000034977	-	99	64.747	Saimiri_boliviensis_boliviensis
ENSG00000100461	RBM23	100	100.000	ENSSBOG00000023037	-	100	94.604	Saimiri_boliviensis_boliviensis
ENSG00000100461	RBM23	100	100.000	ENSSHAG00000012932	RBM23	100	86.681	Sarcophilus_harrisii
ENSG00000100461	RBM23	100	100.000	ENSSARG00000005165	RBM23	100	88.565	Sorex_araneus
ENSG00000100461	RBM23	100	100.000	ENSSPUG00000000489	RBM23	96	71.460	Sphenodon_punctatus
ENSG00000100461	RBM23	100	100.000	ENSSSCG00000026700	RBM23	100	90.069	Sus_scrofa
ENSG00000100461	RBM23	100	100.000	ENSTBEG00000011543	RBM23	100	83.885	Tupaia_belangeri
ENSG00000100461	RBM23	100	100.000	ENSTTRG00000001500	RBM23	100	87.919	Tursiops_truncatus
ENSG00000100461	RBM23	100	100.000	ENSUAMG00000008524	RBM23	100	90.135	Ursus_americanus
ENSG00000100461	RBM23	100	100.000	ENSUMAG00000014075	RBM23	100	90.135	Ursus_maritimus
ENSG00000100461	RBM23	100	100.000	ENSVPAG00000000599	-	57	97.714	Vicugna_pacos
ENSG00000100461	RBM23	100	100.000	ENSVVUG00000019815	RBM23	100	90.787	Vulpes_vulpes
ENSG00000100461	RBM23	100	96.000	ENSXETG00000022623	rbm23	100	64.786	Xenopus_tropicalis

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003723	RNA binding	21873635.	IBA	Function
GO:0003729	mRNA binding	21873635.	IBA	Function
GO:0005515	protein binding	22365833.23455924.23602568.25416956.	IPI	Function
GO:0005634	nucleus	21873635.	IBA	Component
GO:0005634	nucleus	-	IEA	Component
GO:0006397	mRNA processing	-	IEA	Process
GO:0010494	cytoplasmic stress granule	21873635.	IBA	Component
GO:0016020	membrane	19946888.	HDA	Component
GO:0061158	3'-UTR-mediated mRNA destabilization	21873635.	IBA	Process
GO:1990446	U1 snRNP binding	21873635.	IBA	Function
GO:1990904	ribonucleoprotein complex	21873635.	IBA	Component