EuRBPDB

Description

RBDs

RBPome

PRI

Literatures

Expression

Transcripts

Gene Model

Pathways

Phenotypes

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000100836 (Gene tree)
Gene ID: 8106
Gene Symbol: PABPN1
Alias: PAB2|OPMD|PABP2
Full Name: poly(A) binding protein nuclear 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 5,998 bases
Position: chr14:23,320,188-23,326,185
Accession: 8565
RBP type: canonical RBP
Summary: This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene. [provided by RefSeq, Dec 2010]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000450724	RRM_1	PF00076.22	8.8e-15	1	1
ENSP00000451970	RRM_1	PF00076.22	1e-14	1	1
ENSP00000380446	RRM_1	PF00076.22	2.8e-14	1	1
ENSP00000216727	RRM_1	PF00076.22	2.9e-14	1	1
ENSP00000451592	RRM_1	PF00076.22	0.00036	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Protein-RNA interaction（RNA-Binding Site）

Click here to download all RNA binding sites

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
16642034	A Drosophila model of oculopharyngeal muscular dystrophy reveals intrinsic toxicity of PABPN1.	EMBO J	2006 May 17	Chartier A	-
23601051	PABPN1: molecular function and muscle disease.	FEBS J	2013 Sep	Banerjee A	doi: 10.1111/febs.12294
28977530	Nuclear poly(A) binding protein 1 (PABPN1) and Matrin3 interact in muscle cells and regulate RNA processing.	Nucleic Acids Res	2017 Oct 13	Banerjee A	doi: 10.1093/nar/gkx786.
19609631	Bortezomib induces the formation of nuclear poly(A) RNA granules enriched in Sam68 and PABPN1 in sensory ganglia neurons.	Neurotox Res	2010 Feb	Casafont I	doi: 10.1007/s12640-009-9086-1
23612654	The unresolved puzzle why alanine extensions cause disease.	Biol Chem	2013 Aug	Winter R	doi: 10.1515/hsz-2013-0112.
12853485	Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA.	EMBO J	2003 Jul 15	Kerwitz Y	-
12637556	The RNA binding domains of the nuclear poly(A)-binding protein.	J Biol Chem	2003 May 9	Kuhn U	-
17040985	pH-dependent self-assembly of polyalanine peptides.	Biophys J	2007 Jan 1	Giri K	-
21982546	RNA-binding proteins and gene regulation in myogenesis.	Trends Pharmacol Sci	2011 Nov	Apponi LH	doi: 10.1016/j.tips.2011.06.004
21808065	Arginine methylation of the nuclear poly(a) binding protein weakens the interaction with its nuclear import receptor, transportin.	J Biol Chem	2011 Sep 23	Fronz K	doi: 10.1074/jbc.M111.273912
25426070	Oculopharyngeal muscular dystrophy as a paradigm for muscle aging.	Front Aging Neurosci	2014 Nov 10	Raz Y	doi: 10.3389/fnagi.2014.00317
25896913	Poly(A) Polymerase and the Nuclear Poly(A) Binding Protein, PABPN1, Coordinate the Splicing and Degradation of a Subset of Human Pre-mRNAs.	Mol Cell Biol	2015 Jul	Muniz L	doi: 10.1128/MCB.00123-15
29939290	Post-transcriptional regulation of Pabpn1 by the RNA binding protein HuR.	Nucleic Acids Res	2018 Sep 6	Phillips BL	doi: 10.1093/nar/gky535.
29941967	Accumulation of poly(A) RNA in nuclear granules enriched in Sam68 in motor neurons from the SMNdelta7 mouse model of SMA.	Sci Rep	2018 Jun 25	Narcis JO	doi: 10.1038/s41598-018-27821-3.
30040867	Comparative proteomics of the two T. brucei PABPs suggests that PABP2 controls bulk mRNA.	PLoS Negl Trop Dis	2018 Jul 24	Zoltner M	doi: 10.1371/journal.pntd.0006679
11001936	Nuclear inclusions in oculopharyngeal muscular dystrophy consist of poly(A) binding protein 2 aggregates which sequester poly(A) RNA.	Hum Mol Genet	2000 Sep 22	Calado A	-
7852352	Poly(A) tail length control is caused by termination of processive synthesis.	J Biol Chem	1995 Feb 10	Wahle E	doi: 10.1074/jbc.270.6.2800.
10825302	Localization of poly(A)-binding protein 2 (PABP2) in nuclear speckles is independent of import into the nucleus and requires binding to poly(A) RNA.	J Cell Sci	2000 Jun	Calado A	-
19344311	Characterization of PRMT1 from Plasmodium falciparum.	Biochem J	2009 Jun 12	Fan Q	doi: 10.1042/BJ20090185.
23166521	Polyadenylation-dependent control of long noncoding RNA expression by the poly(A)-binding protein nuclear 1.	PLoS Genet	2012	Beaulieu YB	doi: 10.1371/journal.pgen.1003078
12749861	Nuclear poly(A)-binding protein PABPN1 is associated with RNA polymerase II during transcription and accompanies the released transcript to the nuclear pore.	Exp Cell Res	2003 Jun 10	Bear DG	-
18255312	Nuclear compartmentalization and dynamics of the poly(A)-binding protein nuclear 1 (PABPN1) inclusions in supraoptic neurons under physiological and osmotic stress conditions.	Mol Cell Neurosci	2008 Mar	Villagra NT	doi: 10.1016/j.mcn.2007.12.012
22046364	The fission yeast RNA binding protein Mmi1 regulates meiotic genes by controlling intron specific splicing and polyadenylation coupled RNA turnover.	PLoS One	2011	Chen HM	doi: 10.1371/journal.pone.0026804
21964252	Progressive myopathy in an inducible mouse model of oculopharyngeal muscular dystrophy.	Neurobiol Dis	2012 Jan	Mankodi A	doi: 10.1016/j.nbd.2011.09.010
20400847	Crossing the borders: poly(A)-binding proteins working on both sides of the fence.	RNA Biol	2010 May-Jun	Lemay JF	-
24146636	The human nuclear poly(a)-binding protein promotes RNA hyperadenylation and decay.	PLoS Genet	2013	Bresson SM	doi: 10.1371/journal.pgen.1003893

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000556809	PABPN1-206	969	-	-	- (aa)	-	-
ENST00000556821	PABPN1-207	1220	-	ENSP00000451970	178 (aa)	-	G3V4T2
ENST00000557702	PABPN1-208	778	-	ENSP00000450724	168 (aa)	-	B4DEH8
ENST00000553960	PABPN1-203	817	-	-	- (aa)	-	-
ENST00000555295	PABPN1-205	406	-	ENSP00000451592	96 (aa)	-	H0YJH9
ENST00000397276	PABPN1-202	2768	-	ENSP00000380446	296 (aa)	-	Q86U42
ENST00000216727	PABPN1-201	2001	-	ENSP00000216727	306 (aa)	-	Q86U42
ENST00000554062	PABPN1-204	589	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000100836's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03015	mRNA surveillance pathway	KEGG
hsa05164	Influenza A	KEGG

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000100836	Body Mass Index	3E-6	26865924

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000100836's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000100836	PABPN1	94	58.889	ENSG00000205022	PABPN1L	71	50.246

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000100836	PABPN1	94	81.548	ENSAPOG00000016425	pabpn1	86	82.039	Acanthochromis_polyacanthus
ENSG00000100836	PABPN1	100	100.000	ENSAMEG00000007048	BCL2L2-PABPN1	100	100.000	Ailuropoda_melanoleuca
ENSG00000100836	PABPN1	94	82.143	ENSACIG00000021744	pabpn1	94	82.143	Amphilophus_citrinellus
ENSG00000100836	PABPN1	94	81.548	ENSAOCG00000015805	pabpn1	86	82.039	Amphiprion_ocellaris
ENSG00000100836	PABPN1	94	81.548	ENSAPEG00000009623	pabpn1	86	82.039	Amphiprion_percula
ENSG00000100836	PABPN1	94	82.143	ENSATEG00000020531	pabpn1	86	82.524	Anabas_testudineus
ENSG00000100836	PABPN1	94	91.667	ENSACAG00000006185	-	74	87.560	Anolis_carolinensis
ENSG00000100836	PABPN1	100	100.000	ENSANAG00000024513	-	100	90.850	Aotus_nancymaae
ENSG00000100836	PABPN1	90	82.353	ENSACLG00000016374	pabpn1	66	80.905	Astatotilapia_calliptera
ENSG00000100836	PABPN1	94	83.929	ENSAMXG00000000452	pabpn1	94	83.929	Astyanax_mexicanus
ENSG00000100836	PABPN1	86	95.172	ENSBTAG00000050594	-	89	87.255	Bos_taurus
ENSG00000100836	PABPN1	100	100.000	ENSBTAG00000006884	PABPN1	100	99.346	Bos_taurus
ENSG00000100836	PABPN1	100	98.315	ENSBTAG00000053753	-	71	98.429	Bos_taurus
ENSG00000100836	PABPN1	78	62.879	WBGene00003904	pabp-2	91	53.886	Caenorhabditis_elegans
ENSG00000100836	PABPN1	100	100.000	ENSCJAG00000007960	-	100	100.000	Callithrix_jacchus
ENSG00000100836	PABPN1	100	98.315	ENSCJAG00000004407	-	89	98.315	Callithrix_jacchus
ENSG00000100836	PABPN1	100	100.000	ENSCAFG00000011482	PABPN1	100	97.059	Canis_familiaris
ENSG00000100836	PABPN1	100	100.000	ENSCAFG00020007298	-	100	100.000	Canis_lupus_dingo
ENSG00000100836	PABPN1	100	100.000	ENSCAFG00020006651	-	100	100.000	Canis_lupus_dingo
ENSG00000100836	PABPN1	100	100.000	ENSCHIG00000012184	PABPN1	100	99.673	Capra_hircus
ENSG00000100836	PABPN1	100	100.000	ENSTSYG00000033996	BCL2L2-PABPN1	100	100.000	Carlito_syrichta
ENSG00000100836	PABPN1	99	100.000	ENSCAPG00000009461	-	100	99.286	Cavia_aperea
ENSG00000100836	PABPN1	100	99.438	ENSCPOG00000025574	PABPN1	100	98.366	Cavia_porcellus
ENSG00000100836	PABPN1	100	100.000	ENSCCAG00000033954	BCL2L2-PABPN1	100	100.000	Cebus_capucinus
ENSG00000100836	PABPN1	100	100.000	ENSCATG00000038536	BCL2L2-PABPN1	100	100.000	Cercocebus_atys
ENSG00000100836	PABPN1	97	100.000	ENSCLAG00000012423	PABPN1	57	98.026	Chinchilla_lanigera
ENSG00000100836	PABPN1	100	98.876	ENSCSAG00000016036	PABPN1	100	98.366	Chlorocebus_sabaeus
ENSG00000100836	PABPN1	94	91.018	ENSCHOG00000004798	BCL2L2-PABPN1	88	88.293	Choloepus_hoffmanni
ENSG00000100836	PABPN1	94	92.814	ENSCPBG00000026060	-	94	92.814	Chrysemys_picta_bellii
ENSG00000100836	PABPN1	98	64.848	ENSCING00000012468	-	84	65.174	Ciona_intestinalis
ENSG00000100836	PABPN1	100	60.674	ENSCSAVG00000002001	-	93	62.275	Ciona_savignyi
ENSG00000100836	PABPN1	100	100.000	ENSCANG00000009750	BCL2L2-PABPN1	100	100.000	Colobus_angolensis_palliatus
ENSG00000100836	PABPN1	97	90.323	ENSCANG00000030980	-	74	83.902	Colobus_angolensis_palliatus
ENSG00000100836	PABPN1	100	99.438	ENSCGRG00001019696	Pabpn1	100	99.438	Cricetulus_griseus_chok1gshd
ENSG00000100836	PABPN1	100	99.438	ENSCGRG00000011102	Pabpn1	100	99.438	Cricetulus_griseus_crigri
ENSG00000100836	PABPN1	94	81.548	ENSCSEG00000008774	pabpn1	89	80.476	Cynoglossus_semilaevis
ENSG00000100836	PABPN1	94	77.976	ENSCVAG00000003152	pabpn1	86	81.068	Cyprinodon_variegatus
ENSG00000100836	PABPN1	72	65.289	ENSDARG00000087996	pabpn1l	72	66.387	Danio_rerio
ENSG00000100836	PABPN1	94	83.333	ENSDARG00000045373	pabpn1	86	83.495	Danio_rerio
ENSG00000100836	PABPN1	100	100.000	ENSDNOG00000023682	PABPN1	100	100.000	Dasypus_novemcinctus
ENSG00000100836	PABPN1	100	98.876	ENSDORG00000028966	-	100	98.693	Dipodomys_ordii
ENSG00000100836	PABPN1	79	91.729	ENSDORG00000023928	-	85	91.803	Dipodomys_ordii
ENSG00000100836	PABPN1	100	61.236	FBgn0005648	Pabp2	82	63.351	Drosophila_melanogaster
ENSG00000100836	PABPN1	100	78.771	ENSEBUG00000002322	pabpn1	83	79.897	Eptatretus_burgeri
ENSG00000100836	PABPN1	100	100.000	ENSEASG00005011716	PABPN1	100	100.000	Equus_asinus_asinus
ENSG00000100836	PABPN1	99	100.000	ENSECAG00000011652	PABPN1	99	100.000	Equus_caballus
ENSG00000100836	PABPN1	97	91.398	ENSEEUG00000012973	-	72	93.365	Erinaceus_europaeus
ENSG00000100836	PABPN1	94	85.714	ENSELUG00000022654	pabpn1	85	85.437	Esox_lucius
ENSG00000100836	PABPN1	100	100.000	ENSFCAG00000031922	PABPN1	100	100.000	Felis_catus
ENSG00000100836	PABPN1	100	98.876	ENSFDAG00000018381	BCL2L2-PABPN1	100	98.876	Fukomys_damarensis
ENSG00000100836	PABPN1	94	75.595	ENSFHEG00000007215	pabpn1	86	80.097	Fundulus_heteroclitus
ENSG00000100836	PABPN1	92	83.333	ENSGMOG00000003922	pabpn1	66	83.505	Gadus_morhua
ENSG00000100836	PABPN1	94	88.166	ENSGALG00000052930	-	79	73.432	Gallus_gallus
ENSG00000100836	PABPN1	94	81.657	ENSGAFG00000017099	pabpn1	86	82.126	Gambusia_affinis
ENSG00000100836	PABPN1	97	75.532	ENSGACG00000002167	pabpn1	87	77.982	Gasterosteus_aculeatus
ENSG00000100836	PABPN1	100	100.000	ENSGGOG00000022683	-	100	100.000	Gorilla_gorilla
ENSG00000100836	PABPN1	97	82.796	ENSGGOG00000025919	-	98	84.459	Gorilla_gorilla
ENSG00000100836	PABPN1	97	83.871	ENSGGOG00000039675	-	72	84.536	Gorilla_gorilla
ENSG00000100836	PABPN1	94	82.143	ENSHBUG00000019523	pabpn1	86	82.524	Haplochromis_burtoni
ENSG00000100836	PABPN1	93	80.120	ENSHGLG00000018588	-	71	81.429	Heterocephalus_glaber_female
ENSG00000100836	PABPN1	94	76.048	ENSHGLG00000009842	-	93	76.048	Heterocephalus_glaber_female
ENSG00000100836	PABPN1	100	99.438	ENSHGLG00000002927	-	100	98.366	Heterocephalus_glaber_female
ENSG00000100836	PABPN1	93	80.120	ENSHGLG00100015565	-	72	81.429	Heterocephalus_glaber_male
ENSG00000100836	PABPN1	100	99.438	ENSHGLG00100006673	-	100	99.438	Heterocephalus_glaber_male
ENSG00000100836	PABPN1	97	87.629	ENSHGLG00100018935	-	94	88.304	Heterocephalus_glaber_male
ENSG00000100836	PABPN1	94	76.647	ENSHCOG00000004655	pabpn1	86	81.553	Hippocampus_comes
ENSG00000100836	PABPN1	94	79.762	ENSIPUG00000000180	-	86	81.313	Ictalurus_punctatus
ENSG00000100836	PABPN1	94	82.738	ENSIPUG00000008085	PABPN1	86	83.010	Ictalurus_punctatus
ENSG00000100836	PABPN1	100	100.000	ENSSTOG00000029847	BCL2L2-PABPN1	100	100.000	Ictidomys_tridecemlineatus
ENSG00000100836	PABPN1	100	100.000	ENSJJAG00000023507	Gm20521	100	100.000	Jaculus_jaculus
ENSG00000100836	PABPN1	94	81.065	ENSKMAG00000018748	pabpn1	86	81.643	Kryptolebias_marmoratus
ENSG00000100836	PABPN1	94	82.143	ENSLBEG00000027266	pabpn1	86	82.524	Labrus_bergylta
ENSG00000100836	PABPN1	99	81.053	ENSLACG00000000646	pabpn1	79	89.560	Latimeria_chalumnae
ENSG00000100836	PABPN1	100	65.363	ENSLOCG00000004694	pabpn1l	95	65.700	Lepisosteus_oculatus
ENSG00000100836	PABPN1	92	83.974	ENSLOCG00000000796	pabpn1	69	84.021	Lepisosteus_oculatus
ENSG00000100836	PABPN1	97	98.925	ENSLAFG00000031227	-	100	99.338	Loxodonta_africana
ENSG00000100836	PABPN1	97	90.323	ENSMFAG00000031355	-	99	92.908	Macaca_fascicularis
ENSG00000100836	PABPN1	100	100.000	ENSMFAG00000032183	BCL2L2-PABPN1	100	100.000	Macaca_fascicularis
ENSG00000100836	PABPN1	97	90.323	ENSMMUG00000048382	-	68	83.333	Macaca_mulatta
ENSG00000100836	PABPN1	100	100.000	ENSMMUG00000014747	BCL2L2-PABPN1	100	100.000	Macaca_mulatta
ENSG00000100836	PABPN1	97	90.323	ENSMNEG00000035750	-	99	92.908	Macaca_nemestrina
ENSG00000100836	PABPN1	100	100.000	ENSMNEG00000045065	BCL2L2-PABPN1	100	100.000	Macaca_nemestrina
ENSG00000100836	PABPN1	97	87.097	ENSMLEG00000034623	-	99	90.780	Mandrillus_leucophaeus
ENSG00000100836	PABPN1	100	100.000	ENSMLEG00000043862	BCL2L2-PABPN1	100	100.000	Mandrillus_leucophaeus
ENSG00000100836	PABPN1	92	82.051	ENSMAMG00000007979	pabpn1	68	81.773	Mastacembelus_armatus
ENSG00000100836	PABPN1	92	82.051	ENSMZEG00005011904	pabpn1	66	82.474	Maylandia_zebra
ENSG00000100836	PABPN1	100	99.438	ENSMAUG00000007383	Gm20521	99	97.342	Mesocricetus_auratus
ENSG00000100836	PABPN1	100	100.000	ENSMICG00000010002	BCL2L2-PABPN1	100	99.673	Microcebus_murinus
ENSG00000100836	PABPN1	100	98.876	ENSMOCG00000018557	Gm20521	100	97.059	Microtus_ochrogaster
ENSG00000100836	PABPN1	94	82.738	ENSMMOG00000005405	pabpn1	86	83.010	Mola_mola
ENSG00000100836	PABPN1	99	96.988	ENSMODG00000004535	-	99	96.700	Monodelphis_domestica
ENSG00000100836	PABPN1	92	82.051	ENSMALG00000019612	pabpn1	67	81.773	Monopterus_albus
ENSG00000100836	PABPN1	100	97.753	MGP_CAROLIEiJ_G0019276	Gm20521	57	97.884	Mus_caroli
ENSG00000100836	PABPN1	100	97.753	MGP_CAROLIEiJ_G0019277	Pabpn1	100	97.753	Mus_caroli
ENSG00000100836	PABPN1	100	98.315	ENSMUSG00000092232	Gm20521	57	98.413	Mus_musculus
ENSG00000100836	PABPN1	100	98.315	ENSMUSG00000022194	Pabpn1	100	98.315	Mus_musculus
ENSG00000100836	PABPN1	100	98.315	MGP_PahariEiJ_G0030294	Gm20521	57	98.413	Mus_pahari
ENSG00000100836	PABPN1	100	98.315	MGP_PahariEiJ_G0030295	Pabpn1	100	98.315	Mus_pahari
ENSG00000100836	PABPN1	100	98.315	MGP_SPRETEiJ_G0020166	Pabpn1	100	98.315	Mus_spretus
ENSG00000100836	PABPN1	100	98.315	MGP_SPRETEiJ_G0020165	Gm20521	57	98.413	Mus_spretus
ENSG00000100836	PABPN1	100	100.000	ENSMPUG00000006775	-	100	100.000	Mustela_putorius_furo
ENSG00000100836	PABPN1	97	93.548	ENSMLUG00000028677	-	75	94.634	Myotis_lucifugus
ENSG00000100836	PABPN1	94	93.491	ENSMLUG00000012452	-	70	92.958	Myotis_lucifugus
ENSG00000100836	PABPN1	100	98.876	ENSMLUG00000003800	-	100	97.884	Myotis_lucifugus
ENSG00000100836	PABPN1	100	100.000	ENSNGAG00000019529	Gm20521	57	100.000	Nannospalax_galili
ENSG00000100836	PABPN1	94	82.143	ENSNBRG00000023955	pabpn1	94	82.143	Neolamprologus_brichardi
ENSG00000100836	PABPN1	95	67.033	ENSNLEG00000035292	-	99	72.973	Nomascus_leucogenys
ENSG00000100836	PABPN1	100	100.000	ENSNLEG00000015007	-	75	100.000	Nomascus_leucogenys
ENSG00000100836	PABPN1	97	77.419	ENSNLEG00000030598	-	79	81.991	Nomascus_leucogenys
ENSG00000100836	PABPN1	100	99.438	ENSODEG00000002083	BCL2L2-PABPN1	100	98.366	Octodon_degus
ENSG00000100836	PABPN1	100	87.079	ENSODEG00000011555	-	89	86.826	Octodon_degus
ENSG00000100836	PABPN1	97	83.871	ENSODEG00000003739	-	75	86.425	Octodon_degus
ENSG00000100836	PABPN1	92	82.051	ENSONIG00000008112	pabpn1	66	82.474	Oreochromis_niloticus
ENSG00000100836	PABPN1	97	94.624	ENSOANG00000009218	-	100	96.575	Ornithorhynchus_anatinus
ENSG00000100836	PABPN1	100	98.876	ENSOCUG00000016174	PABPN1	100	96.711	Oryctolagus_cuniculus
ENSG00000100836	PABPN1	92	82.692	ENSORLG00000027900	pabpn1	84	79.902	Oryzias_latipes
ENSG00000100836	PABPN1	87	84.932	ENSORLG00020004681	pabpn1	67	82.266	Oryzias_latipes_hni
ENSG00000100836	PABPN1	94	82.738	ENSORLG00015000018	pabpn1	86	83.010	Oryzias_latipes_hsok
ENSG00000100836	PABPN1	92	82.051	ENSOMEG00000016618	pabpn1	68	83.684	Oryzias_melastigma
ENSG00000100836	PABPN1	100	100.000	ENSOGAG00000008710	PABPN1	100	100.000	Otolemur_garnettii
ENSG00000100836	PABPN1	100	100.000	ENSOARG00000019336	BCL2L2-PABPN1	52	100.000	Ovis_aries
ENSG00000100836	PABPN1	94	83.234	ENSPPAG00000039421	-	93	83.234	Pan_paniscus
ENSG00000100836	PABPN1	100	100.000	ENSPPAG00000028984	BCL2L2-PABPN1	100	100.000	Pan_paniscus
ENSG00000100836	PABPN1	100	100.000	ENSPPRG00000010567	PABPN1	100	100.000	Panthera_pardus
ENSG00000100836	PABPN1	100	100.000	ENSPTIG00000001063	BCL2L2-PABPN1	100	100.000	Panthera_tigris_altaica
ENSG00000100836	PABPN1	97	78.495	ENSPTRG00000047273	-	90	66.548	Pan_troglodytes
ENSG00000100836	PABPN1	100	100.000	ENSPTRG00000006167	BCL2L2	100	100.000	Pan_troglodytes
ENSG00000100836	PABPN1	97	90.323	ENSPANG00000023326	-	99	92.908	Papio_anubis
ENSG00000100836	PABPN1	100	100.000	ENSPANG00000021100	BCL2L2-PABPN1	100	100.000	Papio_anubis
ENSG00000100836	PABPN1	93	83.439	ENSPKIG00000018052	pabpn1	86	82.524	Paramormyrops_kingsleyae
ENSG00000100836	PABPN1	94	83.929	ENSPKIG00000008144	-	67	82.266	Paramormyrops_kingsleyae
ENSG00000100836	PABPN1	100	61.453	ENSPKIG00000008340	pabpn1l	92	63.131	Paramormyrops_kingsleyae
ENSG00000100836	PABPN1	73	91.429	ENSPSIG00000011959	-	86	87.179	Pelodiscus_sinensis
ENSG00000100836	PABPN1	92	81.410	ENSPMGG00000022027	pabpn1	69	81.959	Periophthalmus_magnuspinnatus
ENSG00000100836	PABPN1	100	99.438	ENSPEMG00000008332	Gm20521	100	97.386	Peromyscus_maniculatus_bairdii
ENSG00000100836	PABPN1	77	86.923	ENSPMAG00000006212	pabpn1	84	76.355	Petromyzon_marinus
ENSG00000100836	PABPN1	100	97.191	ENSPCIG00000027751	-	100	96.732	Phascolarctos_cinereus
ENSG00000100836	PABPN1	94	78.107	ENSPFOG00000010351	pabpn1	86	80.676	Poecilia_formosa
ENSG00000100836	PABPN1	92	80.892	ENSPLAG00000022696	pabpn1	68	80.882	Poecilia_latipinna
ENSG00000100836	PABPN1	94	78.107	ENSPMEG00000020856	pabpn1	86	80.676	Poecilia_mexicana
ENSG00000100836	PABPN1	94	78.107	ENSPREG00000011278	pabpn1	86	81.159	Poecilia_reticulata
ENSG00000100836	PABPN1	100	100.000	ENSPPYG00000005663	PABPN1	100	94.257	Pongo_abelii
ENSG00000100836	PABPN1	96	98.913	ENSPCAG00000005902	PABPN1	72	85.308	Procavia_capensis
ENSG00000100836	PABPN1	100	100.000	ENSPCOG00000028047	BCL2L2-PABPN1	100	99.673	Propithecus_coquereli
ENSG00000100836	PABPN1	100	97.753	ENSPVAG00000005270	PABPN1	100	97.059	Pteropus_vampyrus
ENSG00000100836	PABPN1	94	82.143	ENSPNYG00000013182	pabpn1	86	82.524	Pundamilia_nyererei
ENSG00000100836	PABPN1	100	62.011	ENSPNAG00000021666	pabpn1l	94	64.179	Pygocentrus_nattereri
ENSG00000100836	PABPN1	94	83.929	ENSPNAG00000023526	pabpn1	86	83.981	Pygocentrus_nattereri
ENSG00000100836	PABPN1	100	98.876	ENSRNOG00000042195	Pabpn1	100	97.059	Rattus_norvegicus
ENSG00000100836	PABPN1	97	91.398	ENSRBIG00000039547	-	75	85.366	Rhinopithecus_bieti
ENSG00000100836	PABPN1	100	100.000	ENSRBIG00000040762	BCL2L2-PABPN1	55	100.000	Rhinopithecus_bieti
ENSG00000100836	PABPN1	95	88.125	ENSRBIG00000042811	-	90	86.636	Rhinopithecus_bieti
ENSG00000100836	PABPN1	92	82.143	ENSRROG00000036409	-	67	82.949	Rhinopithecus_roxellana
ENSG00000100836	PABPN1	97	91.398	ENSRROG00000040409	-	75	85.854	Rhinopithecus_roxellana
ENSG00000100836	PABPN1	100	100.000	ENSRROG00000045535	BCL2L2-PABPN1	100	100.000	Rhinopithecus_roxellana
ENSG00000100836	PABPN1	100	100.000	ENSSBOG00000026930	BCL2L2-PABPN1	100	100.000	Saimiri_boliviensis_boliviensis
ENSG00000100836	PABPN1	97	80.645	ENSSHAG00000007707	-	89	74.408	Sarcophilus_harrisii
ENSG00000100836	PABPN1	100	97.191	ENSSHAG00000014841	-	87	97.354	Sarcophilus_harrisii
ENSG00000100836	PABPN1	94	81.548	ENSSFOG00015014718	pabpn1	86	82.039	Scleropages_formosus
ENSG00000100836	PABPN1	98	64.894	ENSSFOG00015015833	pabpn1l	87	63.918	Scleropages_formosus
ENSG00000100836	PABPN1	94	82.143	ENSSFOG00015012565	pabpn1	90	81.553	Scleropages_formosus
ENSG00000100836	PABPN1	94	82.143	ENSSMAG00000020157	pabpn1	86	82.524	Scophthalmus_maximus
ENSG00000100836	PABPN1	92	82.051	ENSSDUG00000020582	pabpn1	67	81.773	Seriola_dumerili
ENSG00000100836	PABPN1	94	82.143	ENSSLDG00000007118	pabpn1	86	82.524	Seriola_lalandi_dorsalis
ENSG00000100836	PABPN1	94	91.617	ENSSPUG00000018308	-	94	91.617	Sphenodon_punctatus
ENSG00000100836	PABPN1	94	82.143	ENSSPAG00000021658	pabpn1	86	82.524	Stegastes_partitus
ENSG00000100836	PABPN1	95	79.245	ENSSSCG00000034805	-	73	72.581	Sus_scrofa
ENSG00000100836	PABPN1	99	55.114	ENSSSCG00000038472	-	91	54.491	Sus_scrofa
ENSG00000100836	PABPN1	100	100.000	ENSSSCG00000002023	PABPN1	100	100.000	Sus_scrofa
ENSG00000100836	PABPN1	94	82.738	ENSTRUG00000023664	pabpn1	86	83.010	Takifugu_rubripes
ENSG00000100836	PABPN1	93	82.278	ENSTNIG00000005369	pabpn1	93	79.710	Tetraodon_nigroviridis
ENSG00000100836	PABPN1	100	100.000	ENSUAMG00000024460	PABPN1	100	99.346	Ursus_americanus
ENSG00000100836	PABPN1	100	100.000	ENSUMAG00000014288	BCL2L2-PABPN1	57	100.000	Ursus_maritimus
ENSG00000100836	PABPN1	100	100.000	ENSVVUG00000019912	BCL2L2-PABPN1	76	98.446	Vulpes_vulpes
ENSG00000100836	PABPN1	94	89.820	ENSXETG00000014597	pabpn1	66	92.893	Xenopus_tropicalis
ENSG00000100836	PABPN1	97	69.714	ENSXCOG00000005158	pabpn1	89	81.579	Xiphophorus_couchianus
ENSG00000100836	PABPN1	94	78.698	ENSXMAG00000006196	pabpn1	86	81.643	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0000165	MAPK cascade	-	ISS	Process
GO:0000398	mRNA splicing, via spliceosome	-	TAS	Process
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	11371506.15169763.19515850.20467437.23665581.23788676.27871484.	IPI	Function
GO:0005634	nucleus	19364924.27209344.	IDA	Component
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0006369	termination of RNA polymerase II transcription	-	TAS	Process
GO:0006396	RNA processing	9462747.	TAS	Process
GO:0006936	muscle contraction	9462747.	TAS	Process
GO:0016607	nuclear speck	-	IEA	Component
GO:0016973	poly(A)+ mRNA export from nucleus	19364924.	IMP	Process
GO:0031124	mRNA 3'-end processing	-	TAS	Process
GO:0042405	nuclear inclusion body	27209344.	IDA	Component
GO:0046778	modification by virus of host mRNA processing	-	TAS	Process
GO:0070063	RNA polymerase binding	-	ISS	Function
GO:0071222	cellular response to lipopolysaccharide	-	ISS	Process
GO:1904247	positive regulation of polynucleotide adenylyltransferase activity	-	ISS	Process
GO:1990904	ribonucleoprotein complex	17289661.	IDA	Component