EuRBPDB

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  • Description
  • RBPome
  • Expression
  • Transcripts
  • Gene Model
  • Pathways
  • Phenotypes
  • PPI
  • Orthologs
  • Gene Ontology
Description
Ensembl ID
ENSG00000101138 (Gene tree)
Gene ID
1477
Gene Symbol
CSTF1
Alias
N
Full Name
cleavage stimulation factor subunit 1
Gene Type
protein_coding
Species
Homo_sapiens
Status
putative
Strand
Plus strand
Length
13,999 bases
Position
chr20:56,392,371-56,406,369
Accession
2483
RBP type
non-canonical RBP
Summary
This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]
RNA binding proteome (RBPome)
PIDTitleMethod TimeAuthorDoi
22681889The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts4SURIC & HEK2932012 MayBaltz AGDOI: 10.1016/j.molcel.2012.05.021
30607034Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)OOPS & HEK2932019 Jan 3Queiroz RMLDOI: 10.1038/s41587-018-0001-2
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & HEK2932018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
29431736Capturing the interactome of newly transcribed RNAPolyT-RICK & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
29431736Capturing the interactome of newly transcribed RNARIC & Hela2018 Feb 12Bao XDOI: 10.1038/nmeth.4595
22658674Insights into RNA biology from an atlas of mammalian mRNA-binding proteinsRIC & Hela2012 May 31Castello ADOI: 10.1016/j.cell.2012.04.031
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & Hela2018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
30528433The Human RNA-Binding Proteome and Its Dynamics during Translational ArrestXRNAX & MCF72018 Dec 6Trendel JDOI: 10.1016/j.cell.2018.11.004
Expression
Transcripts
Transcript IDNameLengthRefSeq ID Protein IDLengthRefSeq IDUniportKB ID
ENST00000217109CSTF1-2014290XM_011528600ENSP00000217109431 (aa)XP_011526902Q05048
ENST00000493039CSTF1-2062234-ENSP0000047795859 (aa)-A0A087WV92
ENST00000498689CSTF1-207585--- (aa)--
ENST00000490539CSTF1-205929-ENSP0000047927359 (aa)-A0A087WV92
ENST00000452950CSTF1-2041233-ENSP00000409035345 (aa)-A0A0A0MSZ9
ENST00000415828CSTF1-2021236-ENSP00000387968345 (aa)-A0A0A0MSZ9
ENST00000613138CSTF1-208562--- (aa)--
ENST00000428552CSTF1-203554-ENSP00000405171142 (aa)-A3KFI9
Gene Model
Click here to download ENSG00000101138's gene model file
Pathways
Pathway IDPathway NameSource
hsa03015mRNA surveillance pathwayKEGG
Phenotypes
ensgIDTraitpValuePubmed ID
ENSG00000101138Platelet Function Tests2.2800000E-006-
Protein-Protein Interaction (PPI)

Clik here to download ENSG00000101138's network

* RBP PPI network refers to all genes directly bind to RBP
Orthologs identified by RBPome
Ensembl IDGene SymbolCoverageIdentiy OrthologGene SymbolCoverageIdentiy Species
ENSG00000101138CSTF1100100.000ENSMUSG00000027498Cstf1100100.000Mus_musculus
Gene Ontology
Go IDGo_termPubmedIDEvidenceCategory
GO:0000398mRNA splicing, via spliceosome-TASProcess
GO:0003723RNA binding22658674.22681889.HDAFunction
GO:0005515protein binding10477523.21903422.IPIFunction
GO:0005654nucleoplasm-IDAComponent
GO:0005654nucleoplasm-TASComponent
GO:0005848mRNA cleavage stimulating factor complex21873635.IBAComponent
GO:0006369termination of RNA polymerase II transcription-TASProcess
GO:0031124mRNA 3'-end processing-TASProcess

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