EuRBPDB

Description

RBDs

Expression

Transcripts

Gene Model

Phenotypes

GWAS

PPI

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000101246 (Gene tree)
Gene ID: 10139
Gene Symbol: ARFRP1
Alias: ARP|Arp1|ARL18
Full Name: ADP ribosylation factor related protein 1
Gene Type: protein_coding
Species: Homo_sapiens
Status: putative
Strand: Minus strand
Length: 9,384 bases
Position: chr20:63,698,642-63,708,025
Accession: 662
RBP type: canonical RBP
Summary: The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, May 2012]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000479058	MMR_HSR1	PF01926.23	4.9e-07	1	1
ENSP00000479616	MMR_HSR1	PF01926.23	7.2e-07	1	1
ENSP00000479940	MMR_HSR1	PF01926.23	7.2e-07	1	1
ENSP00000483486	MMR_HSR1	PF01926.23	7.2e-07	1	1
ENSP00000483130	MMR_HSR1	PF01926.23	2.1e-06	1	1

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000614942	ARFRP1-210	2554	-	ENSP00000483130	121 (aa)	-	Q13795
ENST00000609537	ARFRP1-204	593	-	-	- (aa)	-	-
ENST00000618568	ARFRP1-211	1612	-	ENSP00000481446	121 (aa)	-	Q13795
ENST00000612256	ARFRP1-208	2974	-	ENSP00000484109	154 (aa)	-	Q13795
ENST00000610414	ARFRP1-205	1251	-	-	- (aa)	-	-
ENST00000618838	ARFRP1-212	1623	XM_011528482	ENSP00000479616	201 (aa)	XP_011526784	Q13795
ENST00000612157	ARFRP1-207	1698	-	ENSP00000479058	173 (aa)	-	Q13795
ENST00000610774	ARFRP1-206	5178	-	-	- (aa)	-	-
ENST00000619493	ARFRP1-213	2456	-	ENSP00000479940	201 (aa)	-	Q13795
ENST00000607873	ARFRP1-202	1061	-	ENSP00000476756	154 (aa)	-	Q13795
ENST00000622789	ARFRP1-214	2559	-	ENSP00000483486	201 (aa)	-	Q13795
ENST00000424545	ARFRP1-201	384	-	-	- (aa)	-	-
ENST00000612772	ARFRP1-209	1375	-	-	- (aa)	-	-
ENST00000609188	ARFRP1-203	225	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000101246's gene model file

Phenotypes

ensgID	Trait	pValue	Pubmed ID
ENSG00000101246	Body Height	3.3110000E-006	-

GWAS

ensgID	SNP	Chromosome	Position	SNP-risk	Trait	PubmedID	95% CI	Or or BEAT	EFO ID
ENSG00000101246	rs6062497	20	63704906	T	Diverticular disease	30177863	[NR] unit decrease	0.0025325	EFO_1001460
ENSG00000101246	rs6062498	20	63707707	G	Age of smoking initiation (MTAG)	30643251	[0.0069-0.013] unit decrease	0.00993772	EFO_0005670
ENSG00000101246	rs1758206	20	63704982	T	Estimated glomerular filtration rate	30604766	[0.17-0.92] ml/min/1.73m2 decrease	0.546	EFO_0005208

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000101246's network

* RBP PPI network refers to all genes directly bind to RBP

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000101246	ARFRP1	96	91.379	ENSAPOG00000010944	arfrp1	100	86.567	Acanthochromis_polyacanthus
ENSG00000101246	ARFRP1	100	97.015	ENSAMEG00000001741	ARFRP1	100	97.015	Ailuropoda_melanoleuca
ENSG00000101246	ARFRP1	96	91.379	ENSACIG00000009740	arfrp1	100	86.567	Amphilophus_citrinellus
ENSG00000101246	ARFRP1	96	91.379	ENSAOCG00000003286	arfrp1	100	86.567	Amphiprion_ocellaris
ENSG00000101246	ARFRP1	96	91.379	ENSAPEG00000003601	arfrp1	100	86.567	Amphiprion_percula
ENSG00000101246	ARFRP1	96	91.379	ENSATEG00000002756	arfrp1	100	86.070	Anabas_testudineus
ENSG00000101246	ARFRP1	100	91.908	ENSAPLG00000014398	ARFRP1	100	91.045	Anas_platyrhynchos
ENSG00000101246	ARFRP1	100	90.173	ENSACAG00000013752	ARFRP1	100	90.050	Anolis_carolinensis
ENSG00000101246	ARFRP1	100	99.422	ENSANAG00000036343	ARFRP1	100	99.174	Aotus_nancymaae
ENSG00000101246	ARFRP1	96	91.379	ENSACLG00000002442	arfrp1	97	86.070	Astatotilapia_calliptera
ENSG00000101246	ARFRP1	96	93.103	ENSAMXG00000042798	arfrp1	100	87.562	Astyanax_mexicanus
ENSG00000101246	ARFRP1	100	97.015	ENSBTAG00000007497	ARFRP1	100	97.015	Bos_taurus
ENSG00000101246	ARFRP1	100	41.618	WBGene00021841	Y54E10BR.2	96	39.572	Caenorhabditis_elegans
ENSG00000101246	ARFRP1	100	98.844	ENSCJAG00000010382	ARFRP1	100	98.507	Callithrix_jacchus
ENSG00000101246	ARFRP1	100	94.527	ENSCAFG00000030493	ARFRP1	100	94.527	Canis_familiaris
ENSG00000101246	ARFRP1	100	97.015	ENSCAFG00020001953	ARFRP1	100	97.015	Canis_lupus_dingo
ENSG00000101246	ARFRP1	100	97.015	ENSCHIG00000010007	ARFRP1	100	97.015	Capra_hircus
ENSG00000101246	ARFRP1	100	98.507	ENSTSYG00000033120	ARFRP1	100	98.507	Carlito_syrichta
ENSG00000101246	ARFRP1	100	96.020	ENSCPOG00000038193	ARFRP1	100	96.020	Cavia_porcellus
ENSG00000101246	ARFRP1	100	98.347	ENSCCAG00000022484	ARFRP1	100	98.347	Cebus_capucinus
ENSG00000101246	ARFRP1	100	100.000	ENSCATG00000039104	ARFRP1	100	100.000	Cercocebus_atys
ENSG00000101246	ARFRP1	100	96.020	ENSCLAG00000004200	ARFRP1	100	96.020	Chinchilla_lanigera
ENSG00000101246	ARFRP1	100	100.000	ENSCSAG00000016609	ARFRP1	100	100.000	Chlorocebus_sabaeus
ENSG00000101246	ARFRP1	100	91.908	ENSCPBG00000014731	ARFRP1	100	91.045	Chrysemys_picta_bellii
ENSG00000101246	ARFRP1	96	77.586	ENSCING00000024645	-	100	67.164	Ciona_intestinalis
ENSG00000101246	ARFRP1	73	79.545	ENSCSAVG00000003938	-	85	79.545	Ciona_savignyi
ENSG00000101246	ARFRP1	100	97.015	ENSCGRG00001001706	Arfrp1	100	97.015	Cricetulus_griseus_chok1gshd
ENSG00000101246	ARFRP1	100	97.015	ENSCGRG00000014284	Arfrp1	100	97.015	Cricetulus_griseus_crigri
ENSG00000101246	ARFRP1	96	91.379	ENSCSEG00000013577	arfrp1	100	86.070	Cynoglossus_semilaevis
ENSG00000101246	ARFRP1	96	93.103	ENSDARG00000057857	arfrp1	100	86.567	Danio_rerio
ENSG00000101246	ARFRP1	100	96.532	ENSDNOG00000001531	-	67	94.527	Dasypus_novemcinctus
ENSG00000101246	ARFRP1	100	97.110	ENSDORG00000013488	Arfrp1	100	96.517	Dipodomys_ordii
ENSG00000101246	ARFRP1	90	30.323	FBgn0038915	CG17819	88	30.233	Drosophila_melanogaster
ENSG00000101246	ARFRP1	96	74.138	FBgn0030088	Arfrp1	100	63.500	Drosophila_melanogaster
ENSG00000101246	ARFRP1	96	81.034	ENSEBUG00000013459	arfrp1	81	76.410	Eptatretus_burgeri
ENSG00000101246	ARFRP1	100	96.517	ENSECAG00000019636	ARFRP1	100	96.517	Equus_caballus
ENSG00000101246	ARFRP1	96	90.517	ENSELUG00000013412	arfrp1	100	84.577	Esox_lucius
ENSG00000101246	ARFRP1	100	97.512	ENSFCAG00000044777	ARFRP1	100	97.512	Felis_catus
ENSG00000101246	ARFRP1	100	91.329	ENSFALG00000005905	ARFRP1	100	90.547	Ficedula_albicollis
ENSG00000101246	ARFRP1	100	95.025	ENSFDAG00000002842	ARFRP1	100	95.025	Fukomys_damarensis
ENSG00000101246	ARFRP1	96	91.379	ENSFHEG00000000458	arfrp1	100	84.577	Fundulus_heteroclitus
ENSG00000101246	ARFRP1	96	92.241	ENSGMOG00000015683	arfrp1	100	86.567	Gadus_morhua
ENSG00000101246	ARFRP1	100	91.908	ENSGALG00000006101	ARFRP1	100	91.045	Gallus_gallus
ENSG00000101246	ARFRP1	96	88.793	ENSGAFG00000006962	arfrp1	100	83.582	Gambusia_affinis
ENSG00000101246	ARFRP1	96	88.793	ENSGACG00000011497	arfrp1	100	84.080	Gasterosteus_aculeatus
ENSG00000101246	ARFRP1	100	91.908	ENSGAGG00000019506	ARFRP1	100	91.045	Gopherus_agassizii
ENSG00000101246	ARFRP1	100	100.000	ENSGGOG00000004799	ARFRP1	100	100.000	Gorilla_gorilla
ENSG00000101246	ARFRP1	73	93.182	ENSHBUG00000006541	arfrp1	62	93.182	Haplochromis_burtoni
ENSG00000101246	ARFRP1	100	95.522	ENSHGLG00000012078	ARFRP1	100	95.522	Heterocephalus_glaber_female
ENSG00000101246	ARFRP1	100	95.522	ENSHGLG00100004198	ARFRP1	100	95.522	Heterocephalus_glaber_male
ENSG00000101246	ARFRP1	95	90.435	ENSHCOG00000005225	arfrp1	100	77.612	Hippocampus_comes
ENSG00000101246	ARFRP1	96	91.379	ENSIPUG00000024487	arfrp1	100	87.065	Ictalurus_punctatus
ENSG00000101246	ARFRP1	100	96.517	ENSSTOG00000011978	ARFRP1	100	96.517	Ictidomys_tridecemlineatus
ENSG00000101246	ARFRP1	100	96.532	ENSJJAG00000013827	Arfrp1	100	96.020	Jaculus_jaculus
ENSG00000101246	ARFRP1	96	92.241	ENSKMAG00000016837	arfrp1	100	87.065	Kryptolebias_marmoratus
ENSG00000101246	ARFRP1	96	90.517	ENSLBEG00000004752	arfrp1	100	85.075	Labrus_bergylta
ENSG00000101246	ARFRP1	98	84.874	ENSLACG00000001971	ARFRP1	98	87.826	Latimeria_chalumnae
ENSG00000101246	ARFRP1	96	92.241	ENSLOCG00000001677	arfrp1	100	80.392	Lepisosteus_oculatus
ENSG00000101246	ARFRP1	100	96.753	ENSLAFG00000010685	ARFRP1	100	96.517	Loxodonta_africana
ENSG00000101246	ARFRP1	100	100.000	ENSMFAG00000001321	ARFRP1	100	100.000	Macaca_fascicularis
ENSG00000101246	ARFRP1	100	100.000	ENSMMUG00000000169	ARFRP1	100	100.000	Macaca_mulatta
ENSG00000101246	ARFRP1	100	99.502	ENSMNEG00000036325	ARFRP1	100	99.502	Macaca_nemestrina
ENSG00000101246	ARFRP1	100	100.000	ENSMLEG00000034228	ARFRP1	100	100.000	Mandrillus_leucophaeus
ENSG00000101246	ARFRP1	96	90.517	ENSMAMG00000019501	arfrp1	100	85.075	Mastacembelus_armatus
ENSG00000101246	ARFRP1	96	91.379	ENSMZEG00005022808	arfrp1	100	86.070	Maylandia_zebra
ENSG00000101246	ARFRP1	100	91.908	ENSMGAG00000006829	ARFRP1	100	91.045	Meleagris_gallopavo
ENSG00000101246	ARFRP1	100	97.015	ENSMAUG00000006741	Arfrp1	100	97.015	Mesocricetus_auratus
ENSG00000101246	ARFRP1	100	99.005	ENSMICG00000008840	ARFRP1	100	99.005	Microcebus_murinus
ENSG00000101246	ARFRP1	100	97.015	ENSMOCG00000003005	Arfrp1	100	97.015	Microtus_ochrogaster
ENSG00000101246	ARFRP1	96	92.241	ENSMMOG00000009657	arfrp1	100	86.567	Mola_mola
ENSG00000101246	ARFRP1	100	90.173	ENSMODG00000017011	ARFRP1	100	90.050	Monodelphis_domestica
ENSG00000101246	ARFRP1	100	97.015	MGP_CAROLIEiJ_G0024805	Arfrp1	100	97.015	Mus_caroli
ENSG00000101246	ARFRP1	100	97.015	ENSMUSG00000038671	Arfrp1	100	97.015	Mus_musculus
ENSG00000101246	ARFRP1	100	97.015	MGP_PahariEiJ_G0026253	Arfrp1	100	97.015	Mus_pahari
ENSG00000101246	ARFRP1	100	97.015	MGP_SPRETEiJ_G0025731	Arfrp1	100	97.015	Mus_spretus
ENSG00000101246	ARFRP1	100	94.805	ENSMPUG00000008452	ARFRP1	100	93.532	Mustela_putorius_furo
ENSG00000101246	ARFRP1	100	96.104	ENSMLUG00000005259	ARFRP1	100	96.020	Myotis_lucifugus
ENSG00000101246	ARFRP1	100	96.517	ENSNGAG00000014373	Arfrp1	100	96.517	Nannospalax_galili
ENSG00000101246	ARFRP1	100	100.000	ENSNLEG00000010131	ARFRP1	100	100.000	Nomascus_leucogenys
ENSG00000101246	ARFRP1	100	90.751	ENSMEUG00000011934	ARFRP1	100	90.547	Notamacropus_eugenii
ENSG00000101246	ARFRP1	100	95.522	ENSOPRG00000003002	-	100	95.522	Ochotona_princeps
ENSG00000101246	ARFRP1	100	96.104	ENSODEG00000006629	ARFRP1	100	96.020	Octodon_degus
ENSG00000101246	ARFRP1	96	91.379	ENSONIG00000005124	arfrp1	100	86.070	Oreochromis_niloticus
ENSG00000101246	ARFRP1	100	91.329	ENSOANG00000004933	ARFRP1	63	90.547	Ornithorhynchus_anatinus
ENSG00000101246	ARFRP1	100	84.416	ENSORLG00000010647	arfrp1	100	84.080	Oryzias_latipes
ENSG00000101246	ARFRP1	100	84.416	ENSORLG00020004500	arfrp1	100	84.080	Oryzias_latipes_hni
ENSG00000101246	ARFRP1	100	83.766	ENSORLG00015022049	arfrp1	100	83.582	Oryzias_latipes_hsok
ENSG00000101246	ARFRP1	100	84.577	ENSOMEG00000001352	arfrp1	100	84.577	Oryzias_melastigma
ENSG00000101246	ARFRP1	100	99.422	ENSOGAG00000026673	ARFRP1	100	99.005	Otolemur_garnettii
ENSG00000101246	ARFRP1	100	97.015	ENSOARG00000010188	ARFRP1	100	97.015	Ovis_aries
ENSG00000101246	ARFRP1	100	100.000	ENSPPAG00000023993	ARFRP1	100	100.000	Pan_paniscus
ENSG00000101246	ARFRP1	100	97.512	ENSPPRG00000024309	ARFRP1	100	97.512	Panthera_pardus
ENSG00000101246	ARFRP1	100	97.110	ENSPTIG00000021097	ARFRP1	100	97.015	Panthera_tigris_altaica
ENSG00000101246	ARFRP1	100	99.502	ENSPTRG00000013747	ARFRP1	100	99.502	Pan_troglodytes
ENSG00000101246	ARFRP1	100	99.502	ENSPTRG00000044739	-	100	99.502	Pan_troglodytes
ENSG00000101246	ARFRP1	100	100.000	ENSPANG00000025599	ARFRP1	100	100.000	Papio_anubis
ENSG00000101246	ARFRP1	96	91.379	ENSPKIG00000006104	arfrp1	97	87.065	Paramormyrops_kingsleyae
ENSG00000101246	ARFRP1	100	90.260	ENSPSIG00000014774	ARFRP1	100	90.050	Pelodiscus_sinensis
ENSG00000101246	ARFRP1	96	91.379	ENSPMGG00000019041	arfrp1	100	86.567	Periophthalmus_magnuspinnatus
ENSG00000101246	ARFRP1	100	90.751	ENSPCIG00000017923	ARFRP1	100	90.547	Phascolarctos_cinereus
ENSG00000101246	ARFRP1	96	90.517	ENSPFOG00000003764	arfrp1	100	84.080	Poecilia_formosa
ENSG00000101246	ARFRP1	96	90.517	ENSPLAG00000022207	arfrp1	100	84.080	Poecilia_latipinna
ENSG00000101246	ARFRP1	96	90.517	ENSPMEG00000013451	arfrp1	100	84.080	Poecilia_mexicana
ENSG00000101246	ARFRP1	96	90.517	ENSPREG00000019667	arfrp1	100	84.080	Poecilia_reticulata
ENSG00000101246	ARFRP1	100	100.000	ENSPPYG00000011245	ARFRP1	100	100.000	Pongo_abelii
ENSG00000101246	ARFRP1	100	93.064	ENSPCAG00000001846	ARFRP1	100	92.386	Procavia_capensis
ENSG00000101246	ARFRP1	100	99.005	ENSPCOG00000024163	ARFRP1	100	99.005	Propithecus_coquereli
ENSG00000101246	ARFRP1	100	94.805	ENSPVAG00000013488	ARFRP1	100	94.527	Pteropus_vampyrus
ENSG00000101246	ARFRP1	96	93.103	ENSPNAG00000003438	arfrp1	100	88.060	Pygocentrus_nattereri
ENSG00000101246	ARFRP1	100	97.015	ENSRNOG00000013992	Arfrp1	100	97.015	Rattus_norvegicus
ENSG00000101246	ARFRP1	100	100.000	ENSRBIG00000044065	ARFRP1	100	100.000	Rhinopithecus_bieti
ENSG00000101246	ARFRP1	100	100.000	ENSRROG00000010121	ARFRP1	100	100.000	Rhinopithecus_roxellana
ENSG00000101246	ARFRP1	100	48.276	YPL051W	-	98	48.223	Saccharomyces_cerevisiae
ENSG00000101246	ARFRP1	100	98.052	ENSSBOG00000021962	ARFRP1	100	97.512	Saimiri_boliviensis_boliviensis
ENSG00000101246	ARFRP1	100	90.751	ENSSHAG00000017842	ARFRP1	100	90.050	Sarcophilus_harrisii
ENSG00000101246	ARFRP1	96	92.241	ENSSFOG00015020500	arfrp1	100	87.065	Scleropages_formosus
ENSG00000101246	ARFRP1	96	88.793	ENSSMAG00000001351	arfrp1	89	84.577	Scophthalmus_maximus
ENSG00000101246	ARFRP1	96	89.655	ENSSDUG00000007121	arfrp1	100	85.572	Seriola_dumerili
ENSG00000101246	ARFRP1	96	89.655	ENSSLDG00000020044	arfrp1	100	85.572	Seriola_lalandi_dorsalis
ENSG00000101246	ARFRP1	100	90.173	ENSSPUG00000018502	ARFRP1	99	90.000	Sphenodon_punctatus
ENSG00000101246	ARFRP1	100	96.517	ENSSSCG00000035304	ARFRP1	100	96.517	Sus_scrofa
ENSG00000101246	ARFRP1	100	91.329	ENSTGUG00000007096	ARFRP1	100	90.547	Taeniopygia_guttata
ENSG00000101246	ARFRP1	96	92.241	ENSTRUG00000009319	arfrp1	100	86.070	Takifugu_rubripes
ENSG00000101246	ARFRP1	100	89.256	ENSTNIG00000005278	arfrp1	100	89.256	Tetraodon_nigroviridis
ENSG00000101246	ARFRP1	100	94.527	ENSTTRG00000012222	ARFRP1	100	94.527	Tursiops_truncatus
ENSG00000101246	ARFRP1	96	89.655	ENSXCOG00000009364	arfrp1	88	84.393	Xiphophorus_couchianus
ENSG00000101246	ARFRP1	96	89.655	ENSXMAG00000002627	arfrp1	100	84.080	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0003924	GTPase activity	8530503.	TAS	Function
GO:0005515	protein binding	11438518.	IPI	Function
GO:0005525	GTP binding	-	IEA	Function
GO:0005794	Golgi apparatus	21873635.	IBA	Component
GO:0005794	Golgi apparatus	19224922.	IDA	Component
GO:0005802	trans-Golgi network	16129887.	IDA	Component
GO:0005829	cytosol	-	TAS	Component
GO:0006886	intracellular protein transport	21873635.	IBA	Process
GO:0007165	signal transduction	8530503.	TAS	Process
GO:0007369	gastrulation	-	IEA	Process
GO:0016020	membrane	8530503.	TAS	Component
GO:0032588	trans-Golgi network membrane	-	TAS	Component
GO:0033365	protein localization to organelle	21873635.	IBA	Process
GO:0034067	protein localization to Golgi apparatus	19224922.	IMP	Process
GO:0042147	retrograde transport, endosome to Golgi	16129887.	IMP	Process
GO:0043001	Golgi to plasma membrane protein transport	21873635.	IBA	Process
GO:0043001	Golgi to plasma membrane protein transport	16129887.19224922.	IMP	Process