EuRBPDB

Basic Information
Cancer Related Information

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Description

Ensembl ID: ENSG00000101361 (Gene tree)
Gene ID: 10528
Gene Symbol: NOP56
Alias: SCA36|NOL5A
Full Name: NOP56 ribonucleoprotein
Gene Type: protein_coding
Species: Homo_sapiens
Status: confidence
Strand: Plus strand
Length: 6,249 bases
Position: chr20:2,652,145-2,658,393
Accession: 15911
RBP type: canonical RBP
Summary: Nop56p is a yeast nucleolar protein that is part of a complex with the nucleolar proteins Nop58p and fibrillarin. Nop56p is required for assembly of the 60S ribosomal subunit and is involved in pre-rRNA processing. The protein encoded by this gene is similar in sequence to Nop56p and is also found in the nucleolus. Expansion of a GGCCTG repeat from 3-8 copies to 1500-2500 copies in an intron of this gene results in spinocerebellar ataxia 36. Multiple transcript variants encoding several different isoforms have been found for this gene, but the full-length nature of most of them has not been determined. [provided by RefSeq, Jul 2016]

RNA binding domains(RBDs)

Protein ID	Domain	Pfam ID	E-value	Domain number	Total number
ENSP00000370589	Nop	PF01798.18	1.4e-86	1	1
ENSP00000403199	Nop	PF01798.18	6.9e-61	1	1
ENSP00000388497	Nop	PF01798.18	9.7e-12	1	1
ENSP00000388497	NOP5NT	PF08156.13	1.7e-17	1	1
ENSP00000370589	NOP5NT	PF08156.13	1.1e-16	1	1

RNA binding proteome (RBPome)

PID	Title	Method	Time	Author	Doi
22681889	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts	4SURIC & HEK293	2012 May	Baltz AG	DOI: 10.1016/j.molcel.2012.05.021
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & HEK293	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & HEK293	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
29431736	Capturing the interactome of newly transcribed RNA	NascentRICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	PolyT-RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RIC & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
29431736	Capturing the interactome of newly transcribed RNA	RICK & Hela	2018 Feb 12	Bao X	DOI: 10.1038/nmeth.4595
22658674	Insights into RNA biology from an atlas of mammalian mRNA-binding proteins	RIC & Hela	2012 May 31	Castello A	DOI: 10.1016/j.cell.2012.04.031
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & Hela	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & MCF10A	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
30528433	The Human RNA-Binding Proteome and Its Dynamics during Translational Arrest	XRNAX & MCF7	2018 Dec 6	Trendel J	DOI: 10.1016/j.cell.2018.11.004
30607034	Comprehensive identification of RNA protein interactions in any organism using orthogonal organic phase separation (OOPS)	OOPS & U2OS	2019 Jan 3	Queiroz RML	DOI: 10.1038/s41587-018-0001-2
27453046	Comprehensive Identification of RNA-Binding Domains in Human Cells	RIC & Hela	2016 Aug 18	Castello A	DOI: 10.1016/j.molcel.2016.06.029
30352994	Discovery of RNA-binding proteins and characterization of their dynamic responses by enhanced RNA interactome capture	RIC & Jurkat	2018 Oct 23	Perez-Perri JI	DOI:10.1038/s41467-018-06557-8

Literatures on RNA binding capacity

PID	Title	Article	Time	Author	Doi
11839271	Archaeal guide RNAs function in rRNA modification in the eukaryotic nucleus.	Curr Biol	2002 Feb 5	Speckmann WA	-
28505348	Implication of the box C/D snoRNP assembly factor Rsa1p in U3 snoRNP assembly.	Nucleic Acids Res	2017 Jul 7	Rothe B	doi: 10.1093/nar/gkx424.
10679243	Identification of casein kinase I substrates by in vitro expression cloning screening.	Biochem Biophys Res Commun	2000 Feb 16	Gao ZH	-
30625028	Compositional reorganization of the nucleolus in budding yeast mitosis.	Mol Biol Cell	2019 Mar 1	Girke P	doi: 10.1091/mbc.E18-08-0524
16949610	Assembly of the archaeal box C/D sRNP can occur via alternative pathways and requires temperature-facilitated sRNA remodeling.	J Mol Biol	2006 Oct 6	Gagnon KT	-

Expression

Transcripts

Transcript ID	Name	Length	RefSeq ID	Protein ID	Length	RefSeq ID	UniportKB ID
ENST00000467196	NOP56-207	1320	-	ENSP00000434317	252 (aa)	-	H0YDU4
ENST00000616692	NOP56-220	2662	-	-	- (aa)	-	-
ENST00000480992	NOP56-213	929	-	-	- (aa)	-	-
ENST00000329276	NOP56-201	2400	-	ENSP00000370589	594 (aa)	-	O00567
ENST00000470143	NOP56-210	663	-	-	- (aa)	-	-
ENST00000462630	NOP56-205	859	-	-	- (aa)	-	-
ENST00000466447	NOP56-206	1094	-	-	- (aa)	-	-
ENST00000469588	NOP56-209	950	-	-	- (aa)	-	-
ENST00000484998	NOP56-214	998	-	-	- (aa)	-	-
ENST00000492135	NOP56-216	1143	-	-	- (aa)	-	-
ENST00000494697	NOP56-217	919	-	-	- (aa)	-	-
ENST00000445139	NOP56-203	856	-	ENSP00000388497	281 (aa)	-	Q5JXT2
ENST00000471023	NOP56-211	592	-	-	- (aa)	-	-
ENST00000490753	NOP56-215	640	-	-	- (aa)	-	-
ENST00000415272	NOP56-202	1628	-	ENSP00000403199	219 (aa)	-	H0Y653
ENST00000467857	NOP56-208	735	-	-	- (aa)	-	-
ENST00000480447	NOP56-212	651	-	-	- (aa)	-	-
ENST00000460258	NOP56-204	837	-	-	- (aa)	-	-
ENST00000612233	NOP56-219	2980	-	-	- (aa)	-	-
ENST00000496775	NOP56-218	729	-	-	- (aa)	-	-

Gene Model

Click here to download ENSG00000101361's gene model file

Pathways

Pathway ID	Pathway Name	Source
hsa03008	Ribosome biogenesis in eukaryotes	KEGG

Protein-Protein Interaction (PPI)

Clik here to download ENSG00000101361's network

* RBP PPI network refers to all genes directly bind to RBP

Paralogs

Ensembl ID	Gene Symbol	Coverage	Identiy	Paralog	Gene Symbol	Coverage	Identiy
ENSG00000101361	NOP56	91	35.741	ENSG00000055044	NOP58	87	49.704

Orthologs

Ensembl ID	Gene Symbol	Coverage	Identiy	Ortholog	Gene Symbol	Coverage	Identiy	Species
ENSG00000101361	NOP56	70	53.595	ENSAPOG00000002127	nop58	75	42.169	Acanthochromis_polyacanthus
ENSG00000101361	NOP56	100	69.504	ENSAPOG00000002789	nop56	99	67.636	Acanthochromis_polyacanthus
ENSG00000101361	NOP56	98	98.785	ENSAMEG00000011299	NOP56	99	93.792	Ailuropoda_melanoleuca
ENSG00000101361	NOP56	89	34.375	ENSAMEG00000013168	NOP58	73	43.627	Ailuropoda_melanoleuca
ENSG00000101361	NOP56	99	68.327	ENSACIG00000018402	nop56	81	79.954	Amphilophus_citrinellus
ENSG00000101361	NOP56	70	54.902	ENSACIG00000021773	nop58	85	43.133	Amphilophus_citrinellus
ENSG00000101361	NOP56	70	54.248	ENSAOCG00000002571	nop58	77	42.410	Amphiprion_ocellaris
ENSG00000101361	NOP56	70	54.248	ENSAPEG00000010178	nop58	75	42.410	Amphiprion_percula
ENSG00000101361	NOP56	100	68.794	ENSAPEG00000002707	nop56	100	69.391	Amphiprion_percula
ENSG00000101361	NOP56	70	54.902	ENSATEG00000009794	nop58	75	43.099	Anabas_testudineus
ENSG00000101361	NOP56	100	68.085	ENSATEG00000023695	nop56	87	69.310	Anabas_testudineus
ENSG00000101361	NOP56	70	54.248	ENSAPLG00000008524	NOP58	82	43.457	Anas_platyrhynchos
ENSG00000101361	NOP56	88	36.255	ENSACAG00000005194	NOP58	95	44.258	Anolis_carolinensis
ENSG00000101361	NOP56	100	72.242	ENSACAG00000005783	NOP56	92	73.346	Anolis_carolinensis
ENSG00000101361	NOP56	98	99.595	ENSANAG00000033253	NOP56	98	95.805	Aotus_nancymaae
ENSG00000101361	NOP56	91	35.361	ENSANAG00000037044	NOP58	85	44.203	Aotus_nancymaae
ENSG00000101361	NOP56	70	55.556	ENSACLG00000024979	nop58	77	43.133	Astatotilapia_calliptera
ENSG00000101361	NOP56	100	69.858	ENSACLG00000012153	nop56	77	81.591	Astatotilapia_calliptera
ENSG00000101361	NOP56	71	54.194	ENSAMXG00000005022	nop58	76	43.645	Astyanax_mexicanus
ENSG00000101361	NOP56	100	70.567	ENSAMXG00000008041	nop56	73	82.727	Astyanax_mexicanus
ENSG00000101361	NOP56	98	98.598	ENSBTAG00000018812	NOP56	97	93.945	Bos_taurus
ENSG00000101361	NOP56	91	35.361	ENSBTAG00000005517	NOP58	74	44.203	Bos_taurus
ENSG00000101361	NOP56	79	72.674	WBGene00010627	K07C5.4	89	59.132	Caenorhabditis_elegans
ENSG00000101361	NOP56	72	53.797	WBGene00020915	nol-5	83	43.675	Caenorhabditis_elegans
ENSG00000101361	NOP56	91	35.361	ENSCJAG00000004985	NOP58	85	44.203	Callithrix_jacchus
ENSG00000101361	NOP56	98	99.190	ENSCJAG00000020999	NOP56	100	95.470	Callithrix_jacchus
ENSG00000101361	NOP56	91	35.741	ENSCAFG00000012448	NOP58	74	44.444	Canis_familiaris
ENSG00000101361	NOP56	98	98.381	ENSCAFG00000006651	NOP56	100	93.645	Canis_familiaris
ENSG00000101361	NOP56	98	98.381	ENSCAFG00020003577	NOP56	100	93.645	Canis_lupus_dingo
ENSG00000101361	NOP56	91	35.741	ENSCAFG00020002394	-	74	44.444	Canis_lupus_dingo
ENSG00000101361	NOP56	98	98.598	ENSCHIG00000023450	NOP56	97	93.599	Capra_hircus
ENSG00000101361	NOP56	89	37.679	ENSTSYG00000006007	NOP58	84	43.672	Carlito_syrichta
ENSG00000101361	NOP56	98	98.785	ENSTSYG00000026366	NOP56	100	94.799	Carlito_syrichta
ENSG00000101361	NOP56	66	52.414	ENSCAPG00000013150	NOP58	76	43.750	Cavia_aperea
ENSG00000101361	NOP56	75	83.886	ENSCAPG00000009320	-	95	97.268	Cavia_aperea
ENSG00000101361	NOP56	53	99.130	ENSCAPG00000013438	-	90	99.130	Cavia_aperea
ENSG00000101361	NOP56	98	97.984	ENSCPOG00000015315	NOP56	97	96.838	Cavia_porcellus
ENSG00000101361	NOP56	66	54.483	ENSCPOG00000030510	NOP58	73	41.404	Cavia_porcellus
ENSG00000101361	NOP56	98	99.595	ENSCCAG00000023832	NOP56	100	95.638	Cebus_capucinus
ENSG00000101361	NOP56	89	39.305	ENSCCAG00000021573	NOP58	76	43.735	Cebus_capucinus
ENSG00000101361	NOP56	100	98.653	ENSCATG00000031167	NOP56	100	98.653	Cercocebus_atys
ENSG00000101361	NOP56	91	35.741	ENSCATG00000037684	NOP58	82	45.745	Cercocebus_atys
ENSG00000101361	NOP56	98	97.984	ENSCLAG00000013816	NOP56	97	93.092	Chinchilla_lanigera
ENSG00000101361	NOP56	89	37.963	ENSCLAG00000003819	NOP58	89	43.961	Chinchilla_lanigera
ENSG00000101361	NOP56	98	100.000	ENSCSAG00000010955	NOP56	99	98.651	Chlorocebus_sabaeus
ENSG00000101361	NOP56	91	35.741	ENSCSAG00000010496	NOP58	85	44.444	Chlorocebus_sabaeus
ENSG00000101361	NOP56	100	85.159	ENSCHOG00000001185	NOP56	99	79.530	Choloepus_hoffmanni
ENSG00000101361	NOP56	71	35.000	ENSCHOG00000011655	NOP58	69	30.214	Choloepus_hoffmanni
ENSG00000101361	NOP56	95	34.066	ENSCPBG00000011565	NOP58	77	42.892	Chrysemys_picta_bellii
ENSG00000101361	NOP56	80	89.143	ENSCPBG00000024420	NOP56	76	81.609	Chrysemys_picta_bellii
ENSG00000101361	NOP56	69	54.967	ENSCING00000005462	-	75	41.446	Ciona_intestinalis
ENSG00000101361	NOP56	80	76.617	ENSCING00000019946	-	79	68.172	Ciona_intestinalis
ENSG00000101361	NOP56	69	54.305	ENSCSAVG00000004558	-	95	39.050	Ciona_savignyi
ENSG00000101361	NOP56	100	98.990	ENSCANG00000039026	NOP56	100	98.990	Colobus_angolensis_palliatus
ENSG00000101361	NOP56	91	31.179	ENSCANG00000010294	NOP58	74	41.546	Colobus_angolensis_palliatus
ENSG00000101361	NOP56	89	37.610	ENSCGRG00001017869	Nop58	89	44.175	Cricetulus_griseus_chok1gshd
ENSG00000101361	NOP56	98	99.595	ENSCGRG00001019528	Nop56	100	90.285	Cricetulus_griseus_chok1gshd
ENSG00000101361	NOP56	89	37.610	ENSCGRG00000006262	Nop58	89	44.175	Cricetulus_griseus_crigri
ENSG00000101361	NOP56	99	86.786	ENSCGRG00000013341	-	94	96.825	Cricetulus_griseus_crigri
ENSG00000101361	NOP56	100	67.730	ENSCSEG00000007169	nop56	79	80.000	Cynoglossus_semilaevis
ENSG00000101361	NOP56	70	53.595	ENSCSEG00000004382	nop58	81	42.615	Cynoglossus_semilaevis
ENSG00000101361	NOP56	100	67.730	ENSCVAG00000017690	nop56	78	79.773	Cyprinodon_variegatus
ENSG00000101361	NOP56	70	54.902	ENSCVAG00000011580	nop58	89	43.767	Cyprinodon_variegatus
ENSG00000101361	NOP56	97	35.579	ENSDARG00000104353	nop58	88	40.984	Danio_rerio
ENSG00000101361	NOP56	83	87.500	ENSDARG00000012820	nop56	99	70.299	Danio_rerio
ENSG00000101361	NOP56	91	35.741	ENSDNOG00000002285	NOP58	75	44.068	Dasypus_novemcinctus
ENSG00000101361	NOP56	98	97.976	ENSDNOG00000042962	NOP56	97	91.275	Dasypus_novemcinctus
ENSG00000101361	NOP56	63	97.810	ENSDORG00000024850	-	94	96.639	Dipodomys_ordii
ENSG00000101361	NOP56	100	86.477	ENSDORG00000013918	-	97	96.443	Dipodomys_ordii
ENSG00000101361	NOP56	89	44.444	FBgn0026196	nop5	79	41.388	Drosophila_melanogaster
ENSG00000101361	NOP56	99	86.758	ENSETEG00000015951	NOP56	100	84.411	Echinops_telfairi
ENSG00000101361	NOP56	66	54.483	ENSETEG00000002057	NOP58	74	39.558	Echinops_telfairi
ENSG00000101361	NOP56	100	65.018	ENSEBUG00000004487	nop56	81	75.000	Eptatretus_burgeri
ENSG00000101361	NOP56	87	33.603	ENSEBUG00000010545	nop58	95	34.572	Eptatretus_burgeri
ENSG00000101361	NOP56	91	35.361	ENSEASG00005002393	NOP58	74	44.203	Equus_asinus_asinus
ENSG00000101361	NOP56	98	99.194	ENSEASG00005012996	NOP56	100	94.816	Equus_asinus_asinus
ENSG00000101361	NOP56	98	99.194	ENSECAG00000021299	NOP56	91	98.734	Equus_caballus
ENSG00000101361	NOP56	91	35.741	ENSECAG00000024696	NOP58	81	44.444	Equus_caballus
ENSG00000101361	NOP56	62	57.037	ENSEEUG00000015752	-	75	38.350	Erinaceus_europaeus
ENSG00000101361	NOP56	98	96.262	ENSEEUG00000001677	NOP56	97	90.261	Erinaceus_europaeus
ENSG00000101361	NOP56	100	68.794	ENSELUG00000010072	nop56	81	80.000	Esox_lucius
ENSG00000101361	NOP56	70	54.902	ENSELUG00000002860	nop58	87	43.584	Esox_lucius
ENSG00000101361	NOP56	98	98.785	ENSFCAG00000014450	NOP56	100	94.472	Felis_catus
ENSG00000101361	NOP56	91	35.361	ENSFCAG00000014093	NOP58	74	42.754	Felis_catus
ENSG00000101361	NOP56	87	36.032	ENSFALG00000004052	NOP58	79	43.478	Ficedula_albicollis
ENSG00000101361	NOP56	80	88.571	ENSFALG00000008947	NOP56	86	78.936	Ficedula_albicollis
ENSG00000101361	NOP56	61	30.133	ENSFDAG00000013317	-	73	30.319	Fukomys_damarensis
ENSG00000101361	NOP56	91	34.981	ENSFDAG00000010143	-	89	43.961	Fukomys_damarensis
ENSG00000101361	NOP56	98	97.581	ENSFDAG00000007422	NOP56	100	90.635	Fukomys_damarensis
ENSG00000101361	NOP56	100	68.085	ENSFHEG00000003342	nop56	81	81.087	Fundulus_heteroclitus
ENSG00000101361	NOP56	70	55.556	ENSFHEG00000008065	nop58	93	42.892	Fundulus_heteroclitus
ENSG00000101361	NOP56	68	56.376	ENSGMOG00000003570	nop58	75	44.226	Gadus_morhua
ENSG00000101361	NOP56	99	67.143	ENSGMOG00000008776	nop56	82	79.224	Gadus_morhua
ENSG00000101361	NOP56	100	73.310	ENSGALG00000032730	NOP56	94	80.716	Gallus_gallus
ENSG00000101361	NOP56	70	54.248	ENSGALG00000008454	NOP58	77	43.961	Gallus_gallus
ENSG00000101361	NOP56	100	68.085	ENSGAFG00000021506	nop56	82	80.227	Gambusia_affinis
ENSG00000101361	NOP56	70	54.902	ENSGAFG00000015066	nop58	87	37.108	Gambusia_affinis
ENSG00000101361	NOP56	70	54.248	ENSGACG00000013746	nop58	98	37.743	Gasterosteus_aculeatus
ENSG00000101361	NOP56	100	67.376	ENSGACG00000008815	nop56	82	78.636	Gasterosteus_aculeatus
ENSG00000101361	NOP56	100	73.665	ENSGAGG00000004324	NOP56	89	80.842	Gopherus_agassizii
ENSG00000101361	NOP56	95	35.055	ENSGAGG00000024049	NOP58	78	43.961	Gopherus_agassizii
ENSG00000101361	NOP56	100	99.327	ENSGGOG00000002886	NOP56	100	99.327	Gorilla_gorilla
ENSG00000101361	NOP56	91	31.698	ENSGGOG00000014545	-	66	36.705	Gorilla_gorilla
ENSG00000101361	NOP56	100	69.504	ENSHBUG00000021495	nop56	80	81.863	Haplochromis_burtoni
ENSG00000101361	NOP56	70	55.556	ENSHBUG00000021827	nop58	75	43.133	Haplochromis_burtoni
ENSG00000101361	NOP56	65	37.063	ENSHGLG00000019315	-	84	33.086	Heterocephalus_glaber_female
ENSG00000101361	NOP56	91	35.361	ENSHGLG00000011278	-	89	44.203	Heterocephalus_glaber_female
ENSG00000101361	NOP56	98	97.984	ENSHGLG00000015992	NOP56	100	91.611	Heterocephalus_glaber_female
ENSG00000101361	NOP56	89	33.575	ENSHGLG00000000430	-	74	38.686	Heterocephalus_glaber_female
ENSG00000101361	NOP56	66	47.945	ENSHGLG00100009239	-	74	38.200	Heterocephalus_glaber_male
ENSG00000101361	NOP56	91	35.361	ENSHGLG00100007782	-	89	44.203	Heterocephalus_glaber_male
ENSG00000101361	NOP56	65	37.500	ENSHGLG00100001097	-	75	33.251	Heterocephalus_glaber_male
ENSG00000101361	NOP56	98	97.984	ENSHGLG00100012337	NOP56	100	92.308	Heterocephalus_glaber_male
ENSG00000101361	NOP56	77	52.976	ENSHCOG00000012934	nop58	78	45.232	Hippocampus_comes
ENSG00000101361	NOP56	84	82.547	ENSHCOG00000012649	nop56	82	77.098	Hippocampus_comes
ENSG00000101361	NOP56	93	81.281	ENSIPUG00000011024	nop56	99	70.194	Ictalurus_punctatus
ENSG00000101361	NOP56	70	55.556	ENSIPUG00000020953	nop58	98	38.502	Ictalurus_punctatus
ENSG00000101361	NOP56	87	36.364	ENSSTOG00000006155	NOP58	89	44.203	Ictidomys_tridecemlineatus
ENSG00000101361	NOP56	98	98.785	ENSSTOG00000012503	NOP56	100	92.605	Ictidomys_tridecemlineatus
ENSG00000101361	NOP56	66	55.172	ENSJJAG00000018213	Nop58	73	42.029	Jaculus_jaculus
ENSG00000101361	NOP56	100	67.376	ENSKMAG00000019440	nop56	99	69.772	Kryptolebias_marmoratus
ENSG00000101361	NOP56	71	54.194	ENSKMAG00000000838	nop58	73	42.373	Kryptolebias_marmoratus
ENSG00000101361	NOP56	100	68.794	ENSLBEG00000000743	nop56	99	68.522	Labrus_bergylta
ENSG00000101361	NOP56	70	54.902	ENSLBEG00000009054	nop58	76	42.892	Labrus_bergylta
ENSG00000101361	NOP56	92	63.218	ENSLACG00000011293	NOP56	84	66.322	Latimeria_chalumnae
ENSG00000101361	NOP56	87	35.628	ENSLACG00000014882	NOP58	74	43.951	Latimeria_chalumnae
ENSG00000101361	NOP56	87	35.628	ENSLOCG00000010225	nop58	75	42.998	Lepisosteus_oculatus
ENSG00000101361	NOP56	98	97.166	ENSLAFG00000001406	NOP56	97	89.655	Loxodonta_africana
ENSG00000101361	NOP56	91	35.849	ENSLAFG00000015568	NOP58	76	44.552	Loxodonta_africana
ENSG00000101361	NOP56	91	35.741	ENSMFAG00000036935	NOP58	75	44.444	Macaca_fascicularis
ENSG00000101361	NOP56	100	98.822	ENSMFAG00000041293	NOP56	100	98.822	Macaca_fascicularis
ENSG00000101361	NOP56	100	98.822	ENSMMUG00000013888	NOP56	100	98.822	Macaca_mulatta
ENSG00000101361	NOP56	91	35.741	ENSMMUG00000000582	NOP58	85	44.444	Macaca_mulatta
ENSG00000101361	NOP56	91	35.741	ENSMNEG00000012760	NOP58	75	44.444	Macaca_nemestrina
ENSG00000101361	NOP56	100	98.653	ENSMNEG00000033186	NOP56	100	98.653	Macaca_nemestrina
ENSG00000101361	NOP56	100	98.822	ENSMLEG00000020816	NOP56	100	98.822	Mandrillus_leucophaeus
ENSG00000101361	NOP56	91	35.741	ENSMLEG00000038485	NOP58	85	43.902	Mandrillus_leucophaeus
ENSG00000101361	NOP56	80	86.286	ENSMAMG00000018655	nop56	76	80.685	Mastacembelus_armatus
ENSG00000101361	NOP56	87	34.694	ENSMAMG00000009967	nop58	75	43.341	Mastacembelus_armatus
ENSG00000101361	NOP56	100	69.858	ENSMZEG00005026863	nop56	77	81.591	Maylandia_zebra
ENSG00000101361	NOP56	70	55.556	ENSMZEG00005000668	nop58	77	43.133	Maylandia_zebra
ENSG00000101361	NOP56	70	54.248	ENSMGAG00000008189	NOP58	73	43.341	Meleagris_gallopavo
ENSG00000101361	NOP56	70	72.222	ENSMGAG00000007493	-	99	85.217	Meleagris_gallopavo
ENSG00000101361	NOP56	98	99.595	ENSMAUG00000021793	Nop56	100	89.262	Mesocricetus_auratus
ENSG00000101361	NOP56	87	35.968	ENSMAUG00000009734	Nop58	89	44.203	Mesocricetus_auratus
ENSG00000101361	NOP56	91	35.361	ENSMICG00000003539	-	85	44.203	Microcebus_murinus
ENSG00000101361	NOP56	66	44.138	ENSMICG00000028354	-	95	33.333	Microcebus_murinus
ENSG00000101361	NOP56	99	98.406	ENSMICG00000016553	NOP56	99	97.468	Microcebus_murinus
ENSG00000101361	NOP56	53	98.276	ENSMOCG00000018981	-	86	98.276	Microtus_ochrogaster
ENSG00000101361	NOP56	100	86.833	ENSMOCG00000004225	-	97	96.838	Microtus_ochrogaster
ENSG00000101361	NOP56	87	35.968	ENSMOCG00000007756	Nop58	89	43.961	Microtus_ochrogaster
ENSG00000101361	NOP56	99	65.836	ENSMMOG00000012293	nop56	79	75.418	Mola_mola
ENSG00000101361	NOP56	91	34.109	ENSMMOG00000004350	nop58	91	43.584	Mola_mola
ENSG00000101361	NOP56	91	34.884	ENSMODG00000016294	NOP58	74	44.010	Monodelphis_domestica
ENSG00000101361	NOP56	98	82.243	ENSMODG00000005184	NOP56	92	85.685	Monodelphis_domestica
ENSG00000101361	NOP56	70	54.902	ENSMALG00000013001	nop58	76	42.615	Monopterus_albus
ENSG00000101361	NOP56	94	70.076	ENSMALG00000001868	nop56	79	80.412	Monopterus_albus
ENSG00000101361	NOP56	87	35.968	MGP_CAROLIEiJ_G0014181	Nop58	85	48.780	Mus_caroli
ENSG00000101361	NOP56	99	98.624	MGP_CAROLIEiJ_G0024295	Nop56	99	97.674	Mus_caroli
ENSG00000101361	NOP56	99	98.624	ENSMUSG00000027405	Nop56	99	98.649	Mus_musculus
ENSG00000101361	NOP56	87	35.968	ENSMUSG00000026020	Nop58	93	46.486	Mus_musculus
ENSG00000101361	NOP56	87	35.968	MGP_PahariEiJ_G0027419	Nop58	85	48.780	Mus_pahari
ENSG00000101361	NOP56	98	98.598	MGP_PahariEiJ_G0025740	Nop56	97	96.443	Mus_pahari
ENSG00000101361	NOP56	87	35.968	MGP_SPRETEiJ_G0014988	Nop58	93	46.486	Mus_spretus
ENSG00000101361	NOP56	90	99.482	MGP_SPRETEiJ_G0025215	Nop56	97	96.443	Mus_spretus
ENSG00000101361	NOP56	91	35.361	ENSMPUG00000000351	NOP58	74	44.203	Mustela_putorius_furo
ENSG00000101361	NOP56	99	97.992	ENSMPUG00000009118	NOP56	100	93.467	Mustela_putorius_furo
ENSG00000101361	NOP56	91	34.848	ENSMLUG00000006896	NOP58	74	43.855	Myotis_lucifugus
ENSG00000101361	NOP56	99	97.222	ENSMLUG00000027085	NOP56	99	90.067	Myotis_lucifugus
ENSG00000101361	NOP56	87	35.968	ENSNGAG00000016443	Nop58	74	44.203	Nannospalax_galili
ENSG00000101361	NOP56	100	87.189	ENSNGAG00000020493	-	97	97.233	Nannospalax_galili
ENSG00000101361	NOP56	62	97.037	ENSNGAG00000019819	-	87	96.610	Nannospalax_galili
ENSG00000101361	NOP56	70	55.556	ENSNBRG00000002165	nop58	81	44.241	Neolamprologus_brichardi
ENSG00000101361	NOP56	100	69.504	ENSNBRG00000018384	nop56	99	68.924	Neolamprologus_brichardi
ENSG00000101361	NOP56	91	35.741	ENSNLEG00000007000	NOP58	75	44.444	Nomascus_leucogenys
ENSG00000101361	NOP56	100	99.158	ENSNLEG00000009178	NOP56	100	99.158	Nomascus_leucogenys
ENSG00000101361	NOP56	99	77.857	ENSMEUG00000002202	NOP56	81	89.387	Notamacropus_eugenii
ENSG00000101361	NOP56	98	99.190	ENSOPRG00000007520	NOP56	100	92.953	Ochotona_princeps
ENSG00000101361	NOP56	63	96.403	ENSODEG00000005708	-	92	78.927	Octodon_degus
ENSG00000101361	NOP56	100	87.544	ENSODEG00000005500	-	97	97.628	Octodon_degus
ENSG00000101361	NOP56	66	54.483	ENSODEG00000010151	NOP58	73	37.379	Octodon_degus
ENSG00000101361	NOP56	70	55.556	ENSONIG00000013196	nop58	75	43.133	Oreochromis_niloticus
ENSG00000101361	NOP56	100	69.504	ENSONIG00000020388	nop56	77	81.364	Oreochromis_niloticus
ENSG00000101361	NOP56	100	75.445	ENSOANG00000000505	NOP56	99	67.832	Ornithorhynchus_anatinus
ENSG00000101361	NOP56	98	98.785	ENSOCUG00000014960	NOP56	100	91.765	Oryctolagus_cuniculus
ENSG00000101361	NOP56	91	35.361	ENSOCUG00000003631	NOP58	76	44.096	Oryctolagus_cuniculus
ENSG00000101361	NOP56	100	68.794	ENSORLG00000008833	nop56	76	80.682	Oryzias_latipes
ENSG00000101361	NOP56	65	56.643	ENSORLG00000003162	nop58	74	43.176	Oryzias_latipes
ENSG00000101361	NOP56	100	68.794	ENSORLG00020008608	nop56	76	80.455	Oryzias_latipes_hni
ENSG00000101361	NOP56	65	56.643	ENSORLG00020021117	nop58	74	43.176	Oryzias_latipes_hni
ENSG00000101361	NOP56	65	56.643	ENSORLG00015020890	nop58	74	43.176	Oryzias_latipes_hsok
ENSG00000101361	NOP56	100	68.440	ENSORLG00015004262	nop56	92	68.245	Oryzias_latipes_hsok
ENSG00000101361	NOP56	70	54.902	ENSOMEG00000000641	nop58	91	40.194	Oryzias_melastigma
ENSG00000101361	NOP56	100	68.794	ENSOMEG00000002458	nop56	80	80.285	Oryzias_melastigma
ENSG00000101361	NOP56	91	35.741	ENSOGAG00000003906	NOP58	75	44.444	Otolemur_garnettii
ENSG00000101361	NOP56	98	91.903	ENSOGAG00000004681	NOP56	99	91.457	Otolemur_garnettii
ENSG00000101361	NOP56	98	96.813	ENSOARG00000006470	NOP56	97	92.955	Ovis_aries
ENSG00000101361	NOP56	91	35.361	ENSOARG00000017569	NOP58	74	44.096	Ovis_aries
ENSG00000101361	NOP56	100	98.990	ENSPPAG00000027513	NOP56	100	98.990	Pan_paniscus
ENSG00000101361	NOP56	91	35.741	ENSPPAG00000036626	NOP58	85	44.444	Pan_paniscus
ENSG00000101361	NOP56	91	35.741	ENSPPRG00000013837	NOP58	74	44.444	Panthera_pardus
ENSG00000101361	NOP56	98	98.785	ENSPPRG00000004623	NOP56	100	94.472	Panthera_pardus
ENSG00000101361	NOP56	98	98.381	ENSPTIG00000012828	NOP56	97	94.876	Panthera_tigris_altaica
ENSG00000101361	NOP56	91	35.741	ENSPTIG00000013131	NOP58	73	44.444	Panthera_tigris_altaica
ENSG00000101361	NOP56	100	98.822	ENSPTRG00000013179	NOP56	100	98.822	Pan_troglodytes
ENSG00000101361	NOP56	91	35.741	ENSPTRG00000012818	NOP58	75	44.444	Pan_troglodytes
ENSG00000101361	NOP56	91	35.741	ENSPANG00000005211	NOP58	91	44.211	Papio_anubis
ENSG00000101361	NOP56	100	98.822	ENSPANG00000023584	NOP56	100	98.822	Papio_anubis
ENSG00000101361	NOP56	71	54.194	ENSPKIG00000003585	nop58	76	43.584	Paramormyrops_kingsleyae
ENSG00000101361	NOP56	83	87.500	ENSPKIG00000017104	nop56	82	81.859	Paramormyrops_kingsleyae
ENSG00000101361	NOP56	83	68.269	ENSPKIG00000016095	-	94	61.877	Paramormyrops_kingsleyae
ENSG00000101361	NOP56	70	54.902	ENSPSIG00000011773	NOP58	69	44.562	Pelodiscus_sinensis
ENSG00000101361	NOP56	80	89.714	ENSPSIG00000006680	NOP56	87	83.144	Pelodiscus_sinensis
ENSG00000101361	NOP56	87	37.977	ENSPMGG00000015380	nop58	79	42.615	Periophthalmus_magnuspinnatus
ENSG00000101361	NOP56	80	87.429	ENSPMGG00000013259	nop56	87	81.280	Periophthalmus_magnuspinnatus
ENSG00000101361	NOP56	91	35.361	ENSPEMG00000021263	-	89	44.203	Peromyscus_maniculatus_bairdii
ENSG00000101361	NOP56	68	52.000	ENSPEMG00000023262	-	73	43.223	Peromyscus_maniculatus_bairdii
ENSG00000101361	NOP56	71	54.194	ENSPMAG00000007901	nop58	74	43.584	Petromyzon_marinus
ENSG00000101361	NOP56	100	67.138	ENSPMAG00000003197	nop56	94	71.316	Petromyzon_marinus
ENSG00000101361	NOP56	98	81.377	ENSPCIG00000005997	NOP56	81	89.041	Phascolarctos_cinereus
ENSG00000101361	NOP56	87	35.887	ENSPCIG00000008839	NOP58	75	44.010	Phascolarctos_cinereus
ENSG00000101361	NOP56	100	68.440	ENSPFOG00000009713	nop56	82	80.410	Poecilia_formosa
ENSG00000101361	NOP56	70	54.902	ENSPFOG00000004114	nop58	82	42.615	Poecilia_formosa
ENSG00000101361	NOP56	70	54.902	ENSPLAG00000004466	nop58	90	42.410	Poecilia_latipinna
ENSG00000101361	NOP56	100	68.440	ENSPLAG00000012463	nop56	82	80.410	Poecilia_latipinna
ENSG00000101361	NOP56	100	68.440	ENSPMEG00000015210	nop56	82	80.410	Poecilia_mexicana
ENSG00000101361	NOP56	70	54.902	ENSPMEG00000007061	nop58	90	42.410	Poecilia_mexicana
ENSG00000101361	NOP56	100	68.440	ENSPREG00000021077	nop56	83	80.182	Poecilia_reticulata
ENSG00000101361	NOP56	70	54.902	ENSPREG00000014125	nop58	89	41.928	Poecilia_reticulata
ENSG00000101361	NOP56	91	35.741	ENSPPYG00000013084	NOP58	76	44.624	Pongo_abelii
ENSG00000101361	NOP56	100	98.990	ENSPPYG00000010838	NOP56	100	98.990	Pongo_abelii
ENSG00000101361	NOP56	91	30.888	ENSPCAG00000006910	NOP58	76	40.385	Procavia_capensis
ENSG00000101361	NOP56	100	85.053	ENSPCAG00000012869	NOP56	79	96.632	Procavia_capensis
ENSG00000101361	NOP56	98	99.190	ENSPCOG00000024681	NOP56	100	94.324	Propithecus_coquereli
ENSG00000101361	NOP56	52	30.719	ENSPCOG00000006096	-	84	57.292	Propithecus_coquereli
ENSG00000101361	NOP56	98	96.761	ENSPVAG00000017030	NOP56	96	91.652	Pteropus_vampyrus
ENSG00000101361	NOP56	68	53.691	ENSPVAG00000002307	NOP58	75	34.783	Pteropus_vampyrus
ENSG00000101361	NOP56	70	55.556	ENSPNYG00000019200	nop58	75	43.133	Pundamilia_nyererei
ENSG00000101361	NOP56	100	69.858	ENSPNYG00000003860	nop56	99	70.175	Pundamilia_nyererei
ENSG00000101361	NOP56	100	70.567	ENSPNAG00000023364	nop56	99	70.506	Pygocentrus_nattereri
ENSG00000101361	NOP56	87	35.223	ENSPNAG00000022346	nop58	76	43.128	Pygocentrus_nattereri
ENSG00000101361	NOP56	98	98.598	ENSRNOG00000007128	Nop56	96	91.901	Rattus_norvegicus
ENSG00000101361	NOP56	87	35.968	ENSRNOG00000016486	Nop58	89	43.961	Rattus_norvegicus
ENSG00000101361	NOP56	91	35.741	ENSRBIG00000043924	NOP58	55	38.768	Rhinopithecus_bieti
ENSG00000101361	NOP56	98	100.000	ENSRBIG00000030689	NOP56	99	98.047	Rhinopithecus_bieti
ENSG00000101361	NOP56	100	98.990	ENSRROG00000020071	NOP56	100	98.990	Rhinopithecus_roxellana
ENSG00000101361	NOP56	91	35.741	ENSRROG00000038002	NOP58	75	44.444	Rhinopithecus_roxellana
ENSG00000101361	NOP56	79	65.143	YLR197W	NOP56	87	54.214	Saccharomyces_cerevisiae
ENSG00000101361	NOP56	92	35.249	YOR310C	NOP58	83	42.369	Saccharomyces_cerevisiae
ENSG00000101361	NOP56	91	32.692	ENSSBOG00000020494	NOP58	73	43.066	Saimiri_boliviensis_boliviensis
ENSG00000101361	NOP56	98	99.595	ENSSBOG00000023623	NOP56	100	95.805	Saimiri_boliviensis_boliviensis
ENSG00000101361	NOP56	67	54.422	ENSSHAG00000011398	NOP58	73	43.250	Sarcophilus_harrisii
ENSG00000101361	NOP56	100	80.071	ENSSHAG00000017162	NOP56	92	85.282	Sarcophilus_harrisii
ENSG00000101361	NOP56	100	69.611	ENSSFOG00015010930	nop56	78	80.045	Scleropages_formosus
ENSG00000101361	NOP56	70	55.556	ENSSFOG00015017870	nop58	76	44.444	Scleropages_formosus
ENSG00000101361	NOP56	100	68.085	ENSSMAG00000009454	nop56	80	80.392	Scophthalmus_maximus
ENSG00000101361	NOP56	91	35.156	ENSSMAG00000000270	nop58	76	43.826	Scophthalmus_maximus
ENSG00000101361	NOP56	91	34.109	ENSSDUG00000008035	nop58	90	43.133	Seriola_dumerili
ENSG00000101361	NOP56	100	69.149	ENSSDUG00000022526	nop56	99	69.097	Seriola_dumerili
ENSG00000101361	NOP56	100	69.149	ENSSLDG00000018177	nop56	99	69.097	Seriola_lalandi_dorsalis
ENSG00000101361	NOP56	91	33.333	ENSSLDG00000020773	nop58	84	42.892	Seriola_lalandi_dorsalis
ENSG00000101361	NOP56	91	35.271	ENSSARG00000013004	NOP58	71	43.152	Sorex_araneus
ENSG00000101361	NOP56	74	79.426	ENSSARG00000009970	-	57	92.222	Sorex_araneus
ENSG00000101361	NOP56	100	73.310	ENSSPUG00000001535	NOP56	86	82.692	Sphenodon_punctatus
ENSG00000101361	NOP56	70	54.248	ENSSPUG00000003921	NOP58	77	45.093	Sphenodon_punctatus
ENSG00000101361	NOP56	70	54.902	ENSSPAG00000022513	nop58	91	37.876	Stegastes_partitus
ENSG00000101361	NOP56	100	68.440	ENSSPAG00000018480	nop56	99	69.217	Stegastes_partitus
ENSG00000101361	NOP56	98	99.190	ENSSSCG00000027676	NOP56	96	93.588	Sus_scrofa
ENSG00000101361	NOP56	91	35.361	ENSSSCG00000022225	NOP58	77	44.203	Sus_scrofa
ENSG00000101361	NOP56	87	36.437	ENSTGUG00000010124	NOP58	77	43.720	Taeniopygia_guttata
ENSG00000101361	NOP56	100	68.440	ENSTRUG00000015355	nop56	84	80.340	Takifugu_rubripes
ENSG00000101361	NOP56	70	54.248	ENSTRUG00000005053	nop58	90	42.615	Takifugu_rubripes
ENSG00000101361	NOP56	100	68.794	ENSTNIG00000010675	nop56	78	80.000	Tetraodon_nigroviridis
ENSG00000101361	NOP56	100	86.833	ENSTBEG00000011249	NOP56	100	87.752	Tupaia_belangeri
ENSG00000101361	NOP56	90	35.115	ENSTBEG00000006153	NOP58	85	34.625	Tupaia_belangeri
ENSG00000101361	NOP56	98	98.780	ENSTTRG00000003451	NOP56	97	91.003	Tursiops_truncatus
ENSG00000101361	NOP56	89	37.968	ENSTTRG00000006018	NOP58	75	43.961	Tursiops_truncatus
ENSG00000101361	NOP56	88	34.661	ENSUAMG00000025100	NOP58	68	45.745	Ursus_americanus
ENSG00000101361	NOP56	98	99.190	ENSUAMG00000006010	NOP56	92	93.289	Ursus_americanus
ENSG00000101361	NOP56	91	35.741	ENSUMAG00000021875	NOP58	92	39.915	Ursus_maritimus
ENSG00000101361	NOP56	98	99.190	ENSUMAG00000002172	NOP56	97	93.471	Ursus_maritimus
ENSG00000101361	NOP56	72	94.709	ENSVPAG00000006173	NOP56	75	94.709	Vicugna_pacos
ENSG00000101361	NOP56	91	31.179	ENSVPAG00000006715	NOP58	73	36.473	Vicugna_pacos
ENSG00000101361	NOP56	91	35.741	ENSVVUG00000018258	NOP58	73	44.444	Vulpes_vulpes
ENSG00000101361	NOP56	98	98.381	ENSVVUG00000025634	NOP56	100	93.478	Vulpes_vulpes
ENSG00000101361	NOP56	67	56.463	ENSXETG00000022073	nop58	83	42.512	Xenopus_tropicalis
ENSG00000101361	NOP56	99	71.071	ENSXETG00000014962	nop56	99	78.588	Xenopus_tropicalis
ENSG00000101361	NOP56	70	54.902	ENSXCOG00000020520	nop58	90	42.651	Xiphophorus_couchianus
ENSG00000101361	NOP56	80	86.286	ENSXCOG00000009216	nop56	93	80.332	Xiphophorus_couchianus
ENSG00000101361	NOP56	100	68.794	ENSXMAG00000001317	nop56	82	80.455	Xiphophorus_maculatus
ENSG00000101361	NOP56	70	54.902	ENSXMAG00000013666	nop58	97	38.185	Xiphophorus_maculatus

Gene Ontology

Go ID	Go_term	PubmedID	Evidence	Category
GO:0001650	fibrillar center	-	IDA	Component
GO:0003723	RNA binding	22658674.22681889.	HDA	Function
GO:0005515	protein binding	17636026.	IPI	Function
GO:0005654	nucleoplasm	-	TAS	Component
GO:0005730	nucleolus	9372940.	TAS	Component
GO:0005732	small nucleolar ribonucleoprotein complex	17636026.	IDA	Component
GO:0005737	cytoplasm	-	IEA	Component
GO:0006364	rRNA processing	-	TAS	Process
GO:0016020	membrane	19946888.	HDA	Component
GO:0030515	snoRNA binding	21873635.	IBA	Function
GO:0030515	snoRNA binding	17636026.	IDA	Function
GO:0031428	box C/D snoRNP complex	21873635.	IBA	Component
GO:0031428	box C/D snoRNP complex	17636026.	NAS	Component
GO:0032040	small-subunit processome	21873635.	IBA	Component
GO:0045296	cadherin binding	25468996.	HDA	Function
GO:0070761	pre-snoRNP complex	17636026.	IDA	Component
GO:1990226	histone methyltransferase binding	17636026.	IPI	Function

Differential Expression

Expression in 33 cancers

Mutations

Cancer	Chr	Position	Mutation Type	dbSNP	Protein-change	Allele Freq	RBD
ACC	chr20	2656864	Missense_Mutation	novel	N417I	0.46
BLCA	chr20	2657952	Missense_Mutation	novel	K481N	0.22
BLCA	chr20	2654242	Intron	novel		0.17
BLCA	chr20	2654871	Missense_Mutation	NA	D165H	0.52
BLCA	chr20	2655198	Intron	novel		0.47
BLCA	chr20	2657152	Missense_Mutation	novel	K451N	0.4
BLCA	chr20	2656646	Intron	novel		0.16
BLCA	chr20	2655358	Silent	NA	V201V	0.15
BLCA	chr20	2656142	Intron	rs756884147		0.15
BLCA	chr20	2656458	Silent	novel	F356F	0.11
BLCA	chr20	2658154	Missense_Mutation	novel	E549K	0.43
BLCA	chr20	2658180	Missense_Mutation	novel	K557N	0.28
BLCA	chr20	2658114	Silent	novel	K535K	0.36
BRCA	chr20	2654838	Missense_Mutation	NA	R154C	0.32
BRCA	chr20	2655428	Missense_Mutation	NA	E225K	0.22
BRCA	chr20	2656949	Intron	NA		0.48
BRCA	chr20	2657673	Intron	novel		0.11
BRCA	chr20	2656874	Silent	novel	V420V	0.08
BRCA	chr20	2657204	Missense_Mutation	NA	P469A	0.18
BRCA	chr20	2655478	Silent	rs141739953	A241A	0.09
BRCA	chr20	2655415	Silent	NA	R220R	0.18
CESC	chr20	2656278	Intron	NA		0.33
CESC	chr20	2656964	Intron	NA		0.22
CESC	chr20	2654879	Missense_Mutation	NA	M167I	0.52
CESC	chr20	2656531	Nonsense_Mutation	novel	R381*	0.36
CESC	chr20	2655203	Intron	NA		0.45
CESC	chr20	2655114	Intron	novel		0.41
CHOL	chr20	2657870	Intron	novel		0.46
COAD	chr20	2653376	Missense_Mutation	NA	A64V	0.16	Nop
COAD	chr20	2657179	Silent	NA	A460A	0.09
COAD	chr20	2656793	Silent	rs146878231	F393F	0.4
COAD	chr20	2657217	Missense_Mutation	NA	E473G	0.3
COAD	chr20	2657523	Intron	novel		0.33
COAD	chr20	2657209	Silent	NA	E470E	0.22
COAD	chr20	2654930	Silent	NA	T184T	0.52
COAD	chr20	2657172	Missense_Mutation	rs763810400	A458V	0.5
COAD	chr20	2656964	Intron	novel		0.2
COAD	chr20	2657995	Missense_Mutation	novel	M496L	0.09
COAD	chr20	2658150	Silent	rs546429113	P547P	0.11
COAD	chr20	2657934	Missense_Mutation	rs541896402	M475I	0.26
COAD	chr20	2658036	Silent	NA	K509K	0.28
COAD	chr20	2655629	Silent	rs147425088	I264I	0.17
COAD	chr20	2652801	Intron	novel		0.29
ESCA	chr20	2657091	Missense_Mutation	rs766864927	A431V	0.22
ESCA	chr20	2658215	Missense_Mutation	novel	S569I	0.14
ESCA	chr20	2658344	3'UTR	novel		0.24
GBM	chr20	2654422	Missense_Mutation	novel	H73Y	0.06
GBM	chr20	2657738	Intron	novel		0.41
GBM	chr20	2656494	Silent	novel	I368I	0.45
GBM	chr20	2656858	Missense_Mutation	rs138219120	R415Q	0.1
GBM	chr20	2652906	Missense_Mutation	NA	E23V	0.15	Nop
HNSC	chr20	2658167	Missense_Mutation	novel	R553K	0.19
HNSC	chr20	2656508	Missense_Mutation	novel	A373V	0.42
HNSC	chr20	2657892	Intron	novel		0.06
HNSC	chr20	2654267	Intron	novel		0.47
HNSC	chr20	2655675	Missense_Mutation	novel	S280G	0.1
KIRC	chr20	2657078	Splice_Region	NA		0.29
KIRC	chr20	2656845	Missense_Mutation	NA	G411R	0.12
KIRC	chr20	2658306	3'UTR	novel		0.22
KIRP	chr20	2655114	Intron	novel		0.41
KIRP	chr20	2655158	Intron	novel		0.31
KIRP	chr20	2652837	Splice_Region	novel		0.24
KIRP	chr20	2655164	Intron	novel		0.58
LAML	chr20	2655173	Intron	novel		0.08
LGG	chr20	2657177	Missense_Mutation	rs374043080	A460T	0.46
LIHC	chr20	2654865	Missense_Mutation	novel	R163W	0.3
LIHC	chr20	2653320	Missense_Mutation	rs759607127	I45M	0.15	Nop
LIHC	chr20	2654812	Missense_Mutation	NA	Q145R	0.42
LIHC	chr20	2654795	Silent	novel	L139L	0.38
LIHC	chr20	2656675	Intron	novel		0.4
LIHC	chr20	2654561	Missense_Mutation	NA	A119G	0.33
LUAD	chr20	2657993	Missense_Mutation	novel	G495E	0.34
LUAD	chr20	2655595	Missense_Mutation	NA	G253V	0.11
LUAD	chr20	2653120	Intron	novel		0.18
LUAD	chr20	2657963	Missense_Mutation	NA	Q485P	0.38
LUAD	chr20	2655727	Nonsense_Mutation	NA	S297*	0.15
LUAD	chr20	2655973	Frame_Shift_Del	novel	*N317Tfs23**	0.14
LUAD	chr20	2656839	Missense_Mutation	NA	E409Q	0.18
LUAD	chr20	2656018	Missense_Mutation	NA	E332K	0.44
LUSC	chr20	2655128	Intron	novel		0.16
LUSC	chr20	2656175	Intron	novel		0.32
LUSC	chr20	2657955	Missense_Mutation	novel	K482N	0.09
LUSC	chr20	2658151	Missense_Mutation	NA	E548Q	0.25
LUSC	chr20	2654530	Missense_Mutation	NA	G109R	0.2
LUSC	chr20	2656179	Intron	novel		0.18
LUSC	chr20	2658272	Missense_Mutation	NA	H588R	0.31
OV	chr20	2658246	Missense_Mutation	NA	S579R	0.3
OV	chr20	2655398	Nonsense_Mutation	NA	Q215*	0.34
OV	chr20	2657708	Intron	novel		0.42
OV	chr20	2655502	Silent	NA	R249R	0.3
OV	chr20	2654233	Intron	NA		0.27
OV	chr20	2655502	Silent	NA	R249R	0.09
OV	chr20	2655378	Missense_Mutation	novel	A208G	0.11
OV	chr20	2658000	Missense_Mutation	NA	E497D	0.19
PAAD	chr20	2655430	Missense_Mutation	novel	E225D	0.2
PAAD	chr20	2655629	Silent	rs147425088	I264I	0.19
PAAD	chr20	2655992	Missense_Mutation	novel	A323V	0.16
PAAD	chr20	2658296	3'UTR	novel		0.16
READ	chr20	2657986	Nonsense_Mutation	NA	E493*	0.26
READ	chr20	2658104	Missense_Mutation	novel	P532H	0.26
READ	chr20	2656194	Intron	novel		0.47
READ	chr20	2656537	Missense_Mutation	NA	D383N	0.52
READ	chr20	2657136	Missense_Mutation	rs143140440	R446H	0.33
READ	chr20	2653309	Missense_Mutation	novel	F42V	0.11	Nop
SKCM	chr20	2655629	Silent	rs147425088	I264I	0.16
SKCM	chr20	2656124	Intron	rs775814004		0.11
SKCM	chr20	2653342	Missense_Mutation	rs374705763	P53S	0.3	Nop
SKCM	chr20	2656061	Intron	novel		0.18
SKCM	chr20	2655442	Silent	rs750390428	E229E	0.32
SKCM	chr20	2657176	Silent	rs757065627	L459L	0.2
SKCM	chr20	2655643	Missense_Mutation	novel	S269I	0.13
SKCM	chr20	2658013	Frame_Shift_Del	novel	*F503Pfs14**	0.17
SKCM	chr20	2654864	Silent	NA	N162N	0.39
SKCM	chr20	2657009	Intron	novel		0.25
SKCM	chr20	2654793	Silent	novel	L139L	0.41
SKCM	chr20	2656055	Intron	novel		0.26
SKCM	chr20	2655449	Missense_Mutation	NA	E232K	0.5
SKCM	chr20	2657976	Silent	novel	E489E	0.26
SKCM	chr20	2657977	Missense_Mutation	novel	V490I	0.25
SKCM	chr20	2656547	Missense_Mutation	NA	S386Y	0.42
SKCM	chr20	2656033	Missense_Mutation	NA	R337G	0.2
SKCM	chr20	2655364	Silent	NA	I203I	0.39
SKCM	chr20	2658073	Missense_Mutation	NA	L522F	0.34
STAD	chr20	2656102	Intron	rs771132481		0.09
STAD	chr20	2654271	Intron	novel		0.28
STAD	chr20	2654940	Missense_Mutation	rs780014888	R188C	0.18
STAD	chr20	2654209	Intron	novel		0.31
STAD	chr20	2656789	Missense_Mutation	novel	V392A	0.23
STAD	chr20	2656965	Intron	rs778409906		0.09
STAD	chr20	2656783	Missense_Mutation	novel	T390M	0.13
STAD	chr20	2656466	Missense_Mutation	rs774972076	R359Q	0.39
STAD	chr20	2658371	3'UTR	novel		0.11
STAD	chr20	2656782	Missense_Mutation	NA	T390A	0.17
STAD	chr20	2656824	Nonsense_Mutation	NA	R404*	0.26
UCEC	chr20	2657709	Intron	novel		0.42
UCEC	chr20	2657000	Intron	NA		0.36
UCEC	chr20	2658349	3'UTR	novel		0.35
UCEC	chr20	2657842	Intron	novel		0.36
UCEC	chr20	2658084	Silent	rs140030798	T525T	0.43
UCEC	chr20	2654838	Missense_Mutation	NA	R154C	0.34
UCEC	chr20	2656806	Nonsense_Mutation	NA	R398*	0.37
UCEC	chr20	2658220	Missense_Mutation	NA	G571W	0.52
UCEC	chr20	2654832	Missense_Mutation	novel	Y152H	0.39
UCEC	chr20	2655433	Silent	novel	D226D	0.38
UCEC	chr20	2656453	Missense_Mutation	novel	T355A	0.36
UCEC	chr20	2657768	Intron	novel		0.38
UCEC	chr20	2654479	Missense_Mutation	rs766330217	L92I	0.36
UCEC	chr20	2653376	Missense_Mutation	NA	A64V	0.4	Nop
UCEC	chr20	2656537	Missense_Mutation	NA	D383N	0.28
UCEC	chr20	2657158	Silent	rs760995038	R453R	0.1
UCEC	chr20	2656208	Intron	novel		0.38
UCEC	chr20	2656209	Intron	novel		0.23
UCEC	chr20	2658388	3'UTR	novel		0.11
UCEC	chr20	2657092	Silent	rs765250821	A431A	0.19
UCEC	chr20	2655721	Missense_Mutation	NA	S295N	0.47
UCEC	chr20	2656806	Nonsense_Mutation	NA	R398*	0.54
UCEC	chr20	2658321	3'UTR	novel		0.33
UCEC	chr20	2656545	Silent	novel	F385F	0.48
UCEC	chr20	2658018	Missense_Mutation	novel	F503L	0.07
UCEC	chr20	2654238	Intron	novel		0.19
UCEC	chr20	2655334	Silent	novel	Y193Y	0.53
UCEC	chr20	2656824	Nonsense_Mutation	NA	R404*	0.42
UCEC	chr20	2654510	Missense_Mutation	NA	A102V	0.32
UCEC	chr20	2654511	Silent	rs144743768	A102A	0.33
UCEC	chr20	2657091	Missense_Mutation	rs766864927	A431V	0.55
UCEC	chr20	2657785	Intron	novel		0.41
UCEC	chr20	2657709	Intron	novel		0.26
UCEC	chr20	2655952	Missense_Mutation	rs370765506	A310T	0.43
UCEC	chr20	2656490	Missense_Mutation	novel	R367H	0.28
UCEC	chr20	2656464	Silent	novel	G358G	0.23
UCEC	chr20	2655638	Missense_Mutation	novel	F267L	0.27
UCEC	chr20	2656773	Splice_Site	novel	X387_splice	0.15
UCEC	chr20	2657135	Missense_Mutation	novel	R446C	0.48
UCEC	chr20	2657199	Missense_Mutation	NA	S467N	0.16
UCEC	chr20	2656646	Intron	novel		0.49
UCEC	chr20	2656824	Nonsense_Mutation	NA	R404*	0.43
UCEC	chr20	2656637	Intron	novel		0.3
UCEC	chr20	2655630	Missense_Mutation	novel	E265K	0.63
UCEC	chr20	2657159	Silent	novel	L454L	0.4
UCEC	chr20	2656983	Intron	novel		0.27
UCEC	chr20	2654754	Missense_Mutation	NA	R126C	0.42
UCEC	chr20	2655188	Intron	novel		0.38
UCEC	chr20	2654512	Missense_Mutation	rs781343694	A103T	0.14
UCEC	chr20	2655745	Missense_Mutation	rs756525659	A303V	0.32
UCEC	chr20	2656821	Nonsense_Mutation	novel	E403*	0.56
UCEC	chr20	2657428	Intron	novel		0.21
UCEC	chr20	2657667	Intron	novel		0.13
UCEC	chr20	2655388	Silent	novel	C211C	0.27
UCEC	chr20	2654865	Silent	novel	R163R	0.38
UCEC	chr20	2655500	Missense_Mutation	novel	R249W	0.42
UCEC	chr20	2658006	Silent	novel	P499P	0.38
UCS	chr20	2658041	Missense_Mutation	NA	S511Y	0.37

Copy Number Variations (CNVs)

Cancer	Type	Freq	Q-value
ACC	DEL	0.1556	0.030954
LUAD	DEL	0.2016	0.15188
OV	AMP	0.4974	0.059168
TGCT	DEL	0.1867	0.14117

Survival Analysis

Cancer	P-value	Q-value
KIRC	0.00011	Kaplan-Meier Survival Analysis
STAD	0.023	Kaplan-Meier Survival Analysis
SARC	0.00042	Kaplan-Meier Survival Analysis
MESO	0.0067	Kaplan-Meier Survival Analysis
ACC	0.0018	Kaplan-Meier Survival Analysis
SKCM	0.05	Kaplan-Meier Survival Analysis
ESCA	0.043	Kaplan-Meier Survival Analysis
KIRP	0.00021	Kaplan-Meier Survival Analysis
PCPG	0.018	Kaplan-Meier Survival Analysis
READ	0.013	Kaplan-Meier Survival Analysis
KICH	0.018	Kaplan-Meier Survival Analysis
UCEC	0.00014	Kaplan-Meier Survival Analysis
LIHC	0.00011	Kaplan-Meier Survival Analysis
UVM	0.00071	Kaplan-Meier Survival Analysis

Drugs

EuRBPDB

Description

RBDs

RBPome

Literatures

Expression

Transcripts

Gene Model

Pathways

PPI

Paralogs

Orthologs

Gene Ontology

Select Dataset :

Input Drug :

Input Cell Line :

Eesembl ID

Cell lines and drugs in GSE70138 or GSE92742